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1

Valor, Cristhian. "3-Amino-2-Piperidinequinoline A Novel Natural Product-Inspiried Synthetic Compound with Antimalarial Activity." Honors in the Major Thesis, University of Central Florida, 2014. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1652.

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Malaria afflicts about 500 million people worldwide thus causing significant global economic toll. The drugs available to treat the disease are rapidly losing their efficacy because of widespread prevalence of drug resistant parasites. Thus there is an urgent need to discover novel malaria therapeutics. This research is focused on to study the properties of a novel naturallike synthetic scaffold and analyze its selectivity, and cellular mechanism of action in Plasmodium falciparum. We have identified a novel compound, 3-amino-2-piperidinequinoline (APQ), which we termed UCF401. APQ demonstrate
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2

Wu, Hanxiang. "Amino acid and glucose conjugates of a phenylpyrrole compound : synthesis, systemicity and biological properties." Thesis, Poitiers, 2017. http://www.theses.fr/2017POIT2261/document.

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Le but de notre travail est de développer une stratégie de vectorisation pour conférer la mobilité phloémienne aux produits agrochimiques en appliquant le concept de prodrogue dans l'élaboration de composés phytopharmaceutiques. Le fenpiclonil, fongicide non systémique de la famille des phénylpyrroles, a été choisi comme composé parent modèle et modifié en l'associant à un acide alpha-aminé ou à un monosaccharide.La mobilité phloémienne des conjugués entre le fenpiclonil et les acides L ou D-glutamique ou le D-glucose (D-GFC) a été évaluée chez des plantules de ricin. Le test de systémie a mon
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3

Ellis, Greg. "Compound-Specific Stable Isotopic Analysis of Protein Amino Acids: Ecological Applications in Modern and Ancient Systems." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4035.

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Stable isotopic analysis of the major biochemically important elements is an increasingly utilized tool in the study of ecology. Patterns of isotopic fractionation in carbon and nitrogen are used to determine trophic linkages, nutrient pathways, and sources of primary production in numerous contexts. Traditional techniques rely on measurements made of bulk samples such as tissue, but emerging methods using individual chemical compounds provide a means of achieving deeper understanding in a variety of inquiries. Amino acids, as the building blocks of proteins, are the dominant nitrogen-bearing
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4

Lee, Aejin. "Investigation of the efficacy of a novel amino acid compound in the treatment of Diabetes Mellitus." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1563380264792334.

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5

McKinnon, Alexander. "The impact of amino acids on growth performance and major volatile compound formation by industrial wine yeast." Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/85797.

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Thesis (MSc)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: Nitrogen composition of grape must is highly variable and impacts on the health of the fermenting yeast population as well as the formation of aroma and flavour compounds in wine. Insufficient yeast assimilable nitrogen (YAN), mostly consisting of amino acids and ammonium, can lead to stuck or sluggish fermentations as well as the formation of undesirable compounds such as H2S. Furthermore, it is well established that the total concentration of YAN and the specific amino acid composition have a significant impact on the fin
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6

Koike, Ryo. "Studise on Separation of Closely Related Compounds by Capillary Electrophoresis." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/77976.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(工学)<br>甲第14634号<br>工博第3102号<br>新制||工||1461(附属図書館)<br>26986<br>UT51-2009-D346<br>京都大学大学院工学研究科材料化学専攻<br>(主査)教授 大塚 浩二, 教授 木村 俊作, 教授 松原 誠二郎<br>学位規則第4条第1項該当
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7

Kugler, Florian [Verfasser]. "Studies into the Betalain Patterns, Free Amino Compound Profiles, and Functional Properties of Betalains in Fruits, Vegetables, and Flowers / Florian Kugler." Aachen : Shaker, 2007. http://d-nb.info/1164339400/34.

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8

Honch, Noah V. "The Palaeodietary Implications of Amino Acid Stable Isotope Analysis : Developments in the Application of Compound Specific Isotope Techniques to Archaeological Bone Collagen." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508412.

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9

Gaudin, Jean-Marc. "Synthèses sélectives à l'aide de complexes du Palladium(0) : élaboration de chaine latérale de stéroïde (glaucastérol), phéromones et alpha-amino esters d'intérêts biologiques." Paris 6, 1986. http://www.theses.fr/1986PA066536.

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Ce travail porte sur l'utilisation de complexe du palladium (0) en catalyse homogène pour la synthèse de molécules d'intérêts biologiques. Trois applications y sont décrites: - la synthèse d'une phéromone secrétée par la reine des abeilles et d'une hormone végétale : l'acide traumatique. La construction du squelette carbone de ces molécules est basée sur une double alkylation d'une bis (aryl sulfonyl) méthane, l'une d'entre elles faisant intervenir un complexe eta (3) allyl palladien fonctionnalisé ; - la synthèse d'alpha-amino esters susceptibles d'être utilisés comme inhibiteur d'enzyme. Cec
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10

Fournel, Jean-Louis. "Synthèse et étude de nouveaux agonistes dopaminergiques : les amino hydroxy tetrahydro quinoléines." Rouen, 1986. http://www.theses.fr/1986ROUES029.

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Synthèse d'hydroxy- ou dihydroxy amino-3 tetrahydro-1,2,3,4 quinoléines par réduction par NABH4 ou par hydrogénations sur palladium d'amino-3 quinoléines ; études de relation structure activité ; calculs MNDO et CNDO
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11

Er-Rhaimini, Abderrahman. "Hétérocycles azotes N-benziles : synthèse de dérivés N-benziles de l'adénine : étude de la photoélimination de substituants benzyliques." Angers, 1986. http://www.theses.fr/1986ANGE0002.

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Synthèse des cinq N-(dimethoxy-3,5 benzyl) adénines. Photolyse de ces compose en solution aqueuse. Tentative de synthèse de l'(imidazo (1,2-a) pyridinyl-6methyl)-1 adénine. Ce travail montre que des substituants benzyliques photoéliminables peuvent être utilisés comme groupes protecteurs dans des synthèses mettant en jeu l'adénine et ses dérivés.
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12

Pignon, Antoine. "Réactions multicomposants aux organométalliques : nouveaux développements et application à la préparation d'hétérocycles azotés." Thesis, Paris Est, 2014. http://www.theses.fr/2014PEST1035.

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Les réactions multicomposants sont des réactions faisant intervenir au minimum trois composés pour la préparation d'un produit contenant la majeure partie des atomes de départ. Elles constituent l'un des procédés les plus performants en synthèse organique. En diminuant les coûts et les rejets par rapport aux réactions classiques de chimie organique, elles sont également plus économes et plus respectueuses de l'environnement. De plus, en permettant la formation rapide et efficace d'une large librairie de molécules complexes à partir de substrats simples, elles représentent un outil à forte vale
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13

Gravena, Renan. "Respostas bioquímicas e fisiológicas de plantas de citros atingidas pelo glyphosate." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/11/11136/tde-24082006-153348/.

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O objetivo deste trabalho foi investigar o comportamento fisiológico e bioquímico de plantas de citros (Citrus spp.) submetidas à aplicação do herbicida glyphosate. Para tanto, foram realizados quatro estudos. No primeiro, avaliou-se o efeito de glyphosate (doses entre 0 e 720 g e.a.ha-1, aplicadas sobre a parte aérea das plantas) nas concentrações foliares de chiquimato, aminoácidos livres totais e fenóis e na fotossíntese de plantas de citros em condições controladas. Foram testadas mudas de limão ‘Cravo’ (Citrus limonia L. Osbeck), com 4 meses de idade, e mudas de ‘Valência’ (Citrus sinensi
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14

Procopio, Susanne Verfasser], Thomas [Akademischer Betreuer] [Gutachter] Becker, and Thomas F. [Gutachter] [Hofmann. "The impact of amino acid availability and gene transcription on aroma compound profiling in Saccharomyces yeast / Susanne Procopio ; Gutachter: Thomas F. Hofmann, Thomas Becker ; Betreuer: Thomas Becker." München : Universitätsbibliothek der TU München, 2016. http://d-nb.info/1124590889/34.

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15

Peschard, Olivier. "Déconjugaison par protonation énantioselective : application à la synthèse de la vinylglycine." Rouen, 1989. http://www.theses.fr/1989ROUES017.

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16

An, Yan. "The Potential of Bulk and Amino-Acid Specific Isotope Ratio Mass Spectrometry of Human Hair in Forensic and Clinical Applications." Ohio University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1363701887.

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17

Demonchaux, Patrice. "Recherche d'agents radioprotecteurs : synthèse et mécanisme d'action de composés de type intercalant-aminothiol." Grenoble 1, 1988. http://www.theses.fr/1988GRE10016.

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Les intercalants utilises sont des amino-9 chloro-6 methoxy-2 acridines des amino-4 chloro-7 quinoleines et des amino-4 chloro-7 methyl-1 quinoleiniums sur lesquels ont ete introduites des chaines analogues a celles de la cysteamine et du wr 2727; etude de l'affinite de ces composes avec l'adn
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18

Jacquelin, Jean-Marie. "Fonctionnalisation par métallation d'amino et d'hydroxy quinoléines : applications à la synthèse de furo quinoléines." Rouen, 1987. http://www.theses.fr/1987ROUES033.

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L'amino-2 quinoléine est fonctionnalisée par métallation en position 3. Les amino-3 et -4 quinoléines ont également été métallées respectivement sur les sommets 2 et 8 mais n'ont pu être fonctionnalisées par des électrophiles carbonés. Les hydroxy-2, -3 et -4 quinoléines masquées sous forme de carbamates sont lithiés régiosélectivement sur les carbones 3, 4 et 3 respectivement. Les dérivés ortho substitués préparés par réaction d'aldéhydes sur les intermédiaires lithiés sont utilisés pour la synthèse de furo-quinoléines
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19

Maddaluno, Jacques. "Synthèse énantiosélective de composés d'intérêt biologique : approche de polyols vicinaux par aldolisation stéréocontrôlée, approche de bêta-amino esters par addition de Michael stéréocontrôlée sous haute pression." Paris 6, 1986. http://www.theses.fr/1986PA066240.

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La réaction d'aldolisation des benzoylaryacetates avec l'acétaldéhyde fait ressortir la capacité de ce synthon à effectuer un transfert d'asymétrie. Etude de la réactivité des alcoxy-3 acroléines. L'addition d'amines primaire sur des crotonates à haute pression permettent d'obtenir de meilleures sélectivités
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20

Epstein, Simon. "Asymmetric synthesis of #alpha#-amino carbonyl compounds." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393570.

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21

CAPET, MARC. "Synthese d'amines allyliques : oxydation de sulfones." Paris 6, 1986. http://www.theses.fr/1986PA066547.

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L'amination allylique des olefines est catalysee par le cuivre ; application a la synthese de la gabaculine en 4 etapes. Les regio- et stereoselectivite de cette reaction sont comparees a celles de l'acetoxylation de kharasch et de sosnovsky. Des sulfones sont oxydees par des complexes peroxydique du molybdene en hydroxysulfones a squelette carbone symetrique
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22

Gardner, Helen. "New methods for the synthesis of amino compounds." Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357640.

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23

Church, Nicola Jane. "Preparation of biologically useful compounds from aziridine-2-carboxylates." Thesis, University of Sussex, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238957.

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24

Chiu, Chun-ming Jack, and 趙鎮明. "Synthesis and NMR studies of N-15 labelled iminopyrans and theirsalts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1985. http://hub.hku.hk/bib/B31207212.

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25

Chiu, Chun-ming Jack. "Synthesis and NMR studies of N-15 labelled iminopyrans and their salts /." [Hong Kong : University of Hong Kong], 1985. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12267338.

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26

Birch, D. J. "The synthesis of biologically active compounds." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233498.

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27

El-Hamruni, Salima Maherize. "Organometallic compounds containing the (dimethylaminodimethylsilyl)bis(trimethylsilyl) methyl ligand." Thesis, University of Sussex, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326949.

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28

Panchanan, Subrata. "Studies on coordination compounds of dioxouranium(VI) and molybdenum with ligands derived from amino acids especially with emidazole, amine and amide r groups." Thesis, University of North Bengal, 1993. http://hdl.handle.net/123456789/739.

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29

Robey, Stephanie. "Reactions of Platinum(II) Compounds with Selenium Containing Amino Acids." TopSCHOLAR®, 2013. http://digitalcommons.wku.edu/theses/1252.

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Platinum(II) anticancer medications essentially react with DNA forming kinks inthe double helix of DNA and causing apoptosis. It has also been noted that theseanticancer medications react with methionine and cysteine in the body. With the new discoveries of selenium containing amino acids including selenomethionine and selenocysteine, new research is ongoing to see what types of products can be formed from these amino acids. Our research reacts [Pt(Met-S,N)Cl2] 2+ with selenomethionine to determine what types of products are produced. Monochelates including [Pt(SeMet-Se,N)Cl2] 2+ have formed t
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30

Fabiano, E. "Synthesis and reactions of amino compounds relating to natural products." Thesis, University of Newcastle Upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373890.

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31

Dubois, Joëlle. "Contribution a l'etude du mecanisme de la carboxylation dependant de la vitamine k." Paris 6, 1987. http://www.theses.fr/1987PA066346.

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32

Delamare, Madeleine. "Nouvelles voies de synthèse d'hétérocycles polyazanaphtalènes en vue de leur application en pharmacie, en agro-industrie et en phytochimie." Rouen, 1998. http://www.theses.fr/1998ROUES024.

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L'activité de produits imidazolés vis-à-vis de l'inhibition de la farnésyl transférase a conduit au développement d'un programme de recherche industriel ayant pour base d'une part un azole et d'autre part un hétérocycle permettant une reconnaissance enzymatique spécifique. Dans le cadre de ce programme, nous nous sommes intéressés aux synthèses de divers hétérocycles de structures polyazanaphtalènes. Ainsi, des 6-acylisoquinol-1(2H)-ones, des 6- et 7-formyl-1,8-naphtyridin-2-ones et des 6- et 7-formyl-1,5-naphtyridin-2-ones, pouvant être substituées en position 3 par un groupe méthyle et en po
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33

Barmettler, Peter. "Säurekatalysierte Amino-Claisen-Umlagerungen von 2, 6-Disubstituierten N-Propargylanilinen." [Fribourg, Switzerland] : Institut für Organische Chemie, Universität Freiburg (Schweiz), 1985. http://catalog.hathitrust.org/api/volumes/oclc/21856572.html.

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34

Ellenberger, Suzanne Ray. "Total synthesis of selected deoxyamino sugars /." Full text open access at:, 1986. http://content.ohsu.edu/u?/etd,110.

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35

Gremyachinskiy, Dmitriy. "Total synthesis of aminomethyl c-glycosides." Scholarly Commons, 2000. https://scholarlycommons.pacific.edu/uop_etds/544.

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36

Boukraa, Sadok. "Préparation, réactivité et étude des propriétés fongistatiques et immunostimulantes d'amino-2 thiazoles et d'imidazo-(2,1-B) thiazoles." Besançon, 1987. http://www.theses.fr/1987BESA2030.

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Le travail se divise en deux grandes parties : la premiere concerne la preparation d'aryl-6 imidazo(2,1-b) thiazoles substitues en 3 par des chaines de type acetate d'ethyle, aroylmethyle. (beta -hydroxy beta -aryl)ethyle te arylethyle. Pour ce faire, il a ete necessaire de preparer les amino-2 thiazoles corespondants substitues par ces memes chaines en 4 afin de las opposer a des acetophenones omega -bromees. L'influence des substituants presents est discutee en vue d'aprehender l'evolution des reactions. La seconde partie concerne des essais en tant que fongistatiques et/ou immunostimulants
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37

Doyle, Alison. "The uptake and metabolism of sulphur compounds by saccharomyces cerevisiae." Thesis, Heriot-Watt University, 1996. http://hdl.handle.net/10399/730.

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38

Li, Jian-Jun. "Platinum(II) hydroxo, oxo, amido, imido and hydrazido complexes /." free to MU campus, to others for purchase, 1996. http://wwwlib.umi.com/cr/mo/fullcit?p9720553.

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39

Foley, Mark Kneale. "Characterisation of the interactions between amino acid derivatives and phenolic compounds." Thesis, Bangor University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443633.

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40

Freeman, James D. "Amino acid ligand mimics : synthons for supramolecular self-assembled coordination compounds." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398796.

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41

Ma, Li. "Soil Organic Nitrogen - Investigation of Soil Amino Acids and Proteinaceous Compounds." Diss., Virginia Tech, 2015. http://hdl.handle.net/10919/51960.

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Soil carbon (C) and nitrogen (N) are predominantly in organic form. Proteins/ peptides, as an important organic form of N, constitute a substantial part of soil organic matter. On one hand, proteins/peptides are an important N source for plants and microorganisms, particularly in soils where inorganic N is limited. On the other hand, their stabilization in soils by forming organo-mineral associates or macromolecule complex reduces the C loss as CO2 into the atmosphere. Therefore, studies on the turnover, abundance, composition, and stability of proteins/peptides are of crucial importance to ag
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42

Gravelle, Philip W. (Philip Wyn). "Part 1. Investigation of Aluminum Amino Acid Complexes; Part 2. Structural Studies of Aluminum Chalcogen Bonds." Thesis, University of North Texas, 1996. https://digital.library.unt.edu/ark:/67531/metadc277846/.

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Five different complexes of aluminum and amino acids have been synthesized and characterized. Reaction between aluminum halides and amino acids that do not contain either a carboxylate or a hydroxy group in the side chain produce complexes of the general formula, [Al(amino acid)_n(halide)_3-n]_m. The most prevalent form of this form of complex is where n = 2, and an example of this in which the halide is replaced by hydroxide ligand has been structurally characterized. The complex for which n = 3 may be obtained by employing a large excess of acid, and that for which n = 1 may be obtained by e
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43

Kuchenbeiser, Glenn Richard. "Reactivity of bis(amino)cyclopropenylidenes (BACs) and cyclic (alkyl)(amino)carbenes (CAACs) coordination chemistry, catalysis, and small molecule activation /." Diss., [Riverside, Calif.] : University of California, Riverside, 2009. http://proquest.umi.com/pqdweb?index=0&did=1899480521&SrchMode=2&sid=4&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1269286714&clientId=48051.

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Thesis (Ph. D.)--University of California, Riverside, 2009.<br>Includes abstract. Available via ProQuest Digital Dissertations. Title from first page of PDF file (viewed March 10, 2010). Includes bibliographical references. Also issued in print.
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44

IZNADEN, MOHAMMED. "Esters d'acides 2h-perfluores : synthese et reactivite." Reims, 1989. http://www.theses.fr/1989REIMS001.

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Les esters d'acides hydro-2 perfluores sont prepares par defluoration photoreductive des esters perfluores correspondants dans l'hexamethylphosphorotriamide. Les proprietes acides de l'hydrogene porte par le carbone-2 ont ete exploitees et des syntheses a haut rendement de composes polyfluores multifonctionnels ont ete realisees: enaminoesters, iminoesters, cetoesters, composes heterocycliques
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45

渠瑾 and Jin Qu. "Novel helices, reversed turns and cyclic peptides containing alpha-aminoxy acids." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B3124225X.

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46

Qu, Jin. "Novel helices, reversed turns and cyclic peptides containing alpha-aminoxy acids /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22713360.

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47

Choi, Mei-yuk. "Synthesis and characterization of some organoruthenium complexes with macrocyclic amine ligands /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20667978.

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48

Jing, Lin. "Chiral Ý-amino sulfoxides and chiral sultams in asymmetric synthesis." HKBU Institutional Repository, 2000. http://repository.hkbu.edu.hk/etd_ra/261.

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49

Wu, Wai Shing. "Measurements of amino acids and aliphatic amines in ambient aerosols /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?CHEM%202003%20WU.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 226-231). Also available in electronic version. Access restricted to campus users.
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50

Salman, Noori Yousif. "Kinetics of oxidation of amino-acids by chloramine-T and related compounds." Thesis, University of Surrey, 1988. http://epubs.surrey.ac.uk/847982/.

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Studies of the kinetics and mechanism of the oxidation of amino-acids by chloramine-T, bromamine-T, di-chloramine-T, N-chlorosuccinimide and N-bromosuccinimide in the range pH 2-9 at 25 or 30&deg;C in aqueous solution are described in this thesis. The effects of added p-toluenesulphonamide, chloride ion, or bromide ion on the rates have been studied. All the previous work on the chloramine-T oxidations of amino-acids was carried out at either pH 9 and the reactions were followed by iodometric titration. In the present work, UV spectrophotometry was used successfully to follow the reactions of
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