Academic literature on the topic 'Anti-arrhythmic strategy'

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Journal articles on the topic "Anti-arrhythmic strategy"

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NAKAZATO, YUJI. "Current Strategy of Anti-arrhythmic Drug Therapy for Persistent Atrial Fibrillation." Juntendo Medical Journal 63, no. 5 (2017): 373–77. http://dx.doi.org/10.14789/jmj.63.373.

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Bond, Richard, Brian Olshansky, and Paulus Kirchhof. "Recent advances in rhythm control for atrial fibrillation." F1000Research 6 (October 3, 2017): 1796. http://dx.doi.org/10.12688/f1000research.11061.1.

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Atrial fibrillation (AF) remains a difficult management problem. The restoration and maintenance of sinus rhythm—rhythm control therapy—can markedly improve symptoms and haemodynamics for patients who have paroxysmal or persistent AF, but some patients fare well with rate control alone. Sinus rhythm can be achieved with anti-arrhythmic drugs or electrical cardioversion, but the maintenance of sinus rhythm without recurrence is more challenging. Catheter ablation of the AF triggers is more effective than anti-arrhythmic drugs at maintaining sinus rhythm. Whilst pulmonary vein isolation is an ef
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Wagner, Michael, Mirna S. Sadek, Nataliya Dybkova, et al. "Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression." International Journal of Molecular Sciences 22, no. 9 (2021): 4816. http://dx.doi.org/10.3390/ijms22094816.

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Background: Phosphodiesterases (PDE) critically regulate myocardial cAMP and cGMP levels. PDE2 is stimulated by cGMP to hydrolyze cAMP, mediating a negative crosstalk between both pathways. PDE2 upregulation in heart failure contributes to desensitization to β-adrenergic overstimulation. After isoprenaline (ISO) injections, PDE2 overexpressing mice (PDE2 OE) were protected against ventricular arrhythmia. Here, we investigate the mechanisms underlying the effects of PDE2 OE on susceptibility to arrhythmias. Methods: Cellular arrhythmia, ion currents, and Ca2+-sparks were assessed in ventricular
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Mezache, Louisa, Gerard Nuovo, and Rengasayee Veeraraghavan. "A Multipronged Microscopy Approach Identifies Common Anti-Arrhythmic Strategy for Atrial Fibrillation and Myocardial Infarction." Microscopy and Microanalysis 27, S1 (2021): 572–73. http://dx.doi.org/10.1017/s1431927621002476.

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Ng, F. S., A. R. Lyon, I. T. Shadi, et al. "D Modulation of gap junctional coupling as an anti-arrhythmic strategy to prevent reperfusion ventricular arrhythmias." Heart 96, Suppl 1 (2010): A2.2—A3. http://dx.doi.org/10.1136/hrt.2010.196113.17.

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Mezache, Louisa, Gerard Nuovo, and Rengasayee Veeraraghavan. "B-PO04-138 VASCULAR BARRIER PROTECTION: A COMMON ANTI-ARRHYTHMIC STRATEGY FOR ATRIAL FIBRILLATION AND MYOCARDIAL INFARCTION." Heart Rhythm 18, no. 8 (2021): S335—S336. http://dx.doi.org/10.1016/j.hrthm.2021.06.832.

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Huang, Weiting, Felix YJ Keng, and Chi Keong Ching. "Rate or Rhythm Control of Atrial Fibrillation – Pearls for the Internist." Annals of the Academy of Medicine, Singapore 46, no. 11 (2017): 433–38. http://dx.doi.org/10.47102/annals-acadmedsg.v46n11p433.

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Atrial fibrillation is an epidemic in Asia that is increasingly prevalent. Apart from stroke risk stratification and management of anticoagulation, physicians managing this group of patients also need to determine an optimal strategy in terms of rate or rhythm control. With new techniques of catheter ablation to maintain patients in sinus rhythm, patients with atrial fibrillation now have more options for treatment, on top of pharmacological methods. This paper aims to review the current evidence for rate and rhythm control in both general patients and subgroups of interest commonly encountere
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Brizzi, Antonella, Alfonso Trezza, Ottavia Spiga, et al. "2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: Synthesis, In Silico Analysis and In Vitro Pharmacological Evaluation." Molbank 2021, no. 3 (2021): M1258. http://dx.doi.org/10.3390/m1258.

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Quercetin and ferulic acid are two phytochemicals extensively represented in the plant kingdom and daily consumed in considerable amounts through diets. Due to a common phenolic structure, these two molecules share several pharmacological properties, e.g., antioxidant and free radical scavenging, anti-cancer, anti-inflammatory, anti-arrhythmic, and vasorelaxant. The aim of the present work was the combination of the two molecules in a single chemical entity, conceivably endowed with more efficacious vasorelaxant activity. Preliminary in silico studies herein described suggested that the new hy
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Migliore, Federico, Giulia Mattesi, Alessandro Zorzi, et al. "Arrhythmogenic Cardiomyopathy—Current Treatment and Future Options." Journal of Clinical Medicine 10, no. 13 (2021): 2750. http://dx.doi.org/10.3390/jcm10132750.

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Arrhythmogenic cardiomyopathy (ACM) is an inheritable heart muscle disease characterised pathologically by fibrofatty myocardial replacement and clinically by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). Although, in its original description, the disease was believed to predominantly involve the right ventricle, biventricular and left-dominant variants, in which the myocardial lesions affect in parallel or even mostly the left ventricle, are nowadays commonly observed. The clinical management of these patients has two main purposes: the prevention of SCD and the control of arr
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Palazzuoli, Alberto, Matteo Beltrami, and Peter A. McCullough. "Acute COVID-19 Management in Heart Failure Patients: A Specific Setting Requiring Detailed Inpatient and Outpatient Hospital Care." Biomedicines 11, no. 3 (2023): 790. http://dx.doi.org/10.3390/biomedicines11030790.

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The relationship existing between heart failure (HF) and COVID-19 remains questioned and poorly elucidated. Many reports suggest that HF events are reduced during pandemics, although other studies have demonstrated higher mortality and sudden death in patients affected by HF. Several vascular, thrombotic, and respiratory features may deteriorate stable HF patients; therefore, the infection may directly cause direct myocardial damage, leading to cardiac function deterioration. Another concern is related to the possibility that antiviral, anti-inflammatory, and corticosteroid agents commonly emp
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Dissertations / Theses on the topic "Anti-arrhythmic strategy"

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Steccanella, Federica. "The relevance of L-type calcium channel gating properties to cardiac arrhythmia and differential modulation of L-type CaV channels by the α2δ-1 auxiliary subunit". Doctoral thesis, 2019. http://hdl.handle.net/11562/998380.

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L-type voltage-dependent calcium (Ca2+) channels (CaV1.2) initiate cardiac excitation-contraction coupling producing a rapid Ca2+ current (peak ICa,L) that triggers Ca2+ release from the intracellular stores, and a persistent current (late ICa,L) that flows towards the end of the action potential (AP). Peak and late ICa,L shape the plateau phase of the AP, counterbalancing potassium currents. An exaggerated activation of the late ICa,L during AP repolarization can cause transient membrane potential depolarizations called Early Afterdepolarizations (EADs), that can trigger lethal arrhythmias. T
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Book chapters on the topic "Anti-arrhythmic strategy"

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Pullaiah, Chitikela P., Vinod K. Nelson, T. S. Mohamed Saleem, et al. "Andrographolide and its Analogs as Cardioprotective Agents." In Andrographolide and its Analogs: Botanical Sources, Phytochemistry, Pharmacology, and Biotechnology. BENTHAM SCIENCE PUBLISHERS, 2024. https://doi.org/10.2174/9789815256567124010014.

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Myocardial infarction is a sudden and fatal disease that causes a significant number of deaths in the world. The current treatment strategy for MI is only for symptomatic relief and cannot cure or reverse the disease condition. Hence, there is a need to identify novel, definitive, and minimal toxic drugs to treat MI. Phytochemicals always draw attention as an alternative and upgraded choice to combat various ailments. Photochemical compounds are non-nutritive biologically active secondary metabolites abundantly found in plants. Andrographolide and its derivatives obtained from a medicinal herb
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