Academic literature on the topic 'Anti fire hazard'

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Journal articles on the topic "Anti fire hazard"

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Stahler, Arndt, Dominik Paul Modest, Sebastian Stintzing, et al. "Consensus molecular subtypes (CMS) as prognostic and predictive biomarkers of RAS wild-type (WT) metastatic colorectal cancer (mCRC): Pooled analysis of the randomized trials FIRE-1, FIRE-3, XELAVIRI, and PanaMa." Journal of Clinical Oncology 42, no. 16_suppl (2024): 3529. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.3529.

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3529 Background: CMS were associated with prognostic relevance in RAS WT mCRC, while their role as predictive biomarker is debatable. We aimed to assess the predictive impact of CMS on treatment with anti-EGFR vs. anti-VEGF antibodies vs. cytotoxic treatment alone in a pooled analysis. Methods: Available CMS data (called by predictedCMS method) of the randomized controlled trials FIRE-1 (FUFIRI vs. mIrOx); FIRE-3 (FOLFIRI+ cetuximab vs. bevacizumab), XELAVIRI (sequential vs. initially combined FOLFIRI+bevacizumab) and PanaMa (FOLFOX+panitumumab followed by FU/FA +/- panitumumab) of RAS WT mCRC
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Politi, Nadia, Diamando Vlachogiannis, and Athanasios Sfetsos. "A Statistical Analysis of Drought and Fire Weather Indicators in the Context of Climate Change: The Case of the Attica Region, Greece." Climate 12, no. 9 (2024): 135. http://dx.doi.org/10.3390/cli12090135.

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As warmer and drier conditions associated with global warming are projected to increase in southern Europe, the Mediterranean countries are currently the most prone to wildfire danger. In the present study, we investigated the statistical relationship between drought and fire weather risks in the context of climate change using drought index and fire weather-related indicators. We focused on the vulnerable and long-suffering area of the Attica region using high-resolution gridded climate datasets. Concerning fire weather components and fire hazard days, the majority of Attica consistently prod
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Wang, Jingyuan, Joshua Millstein, Fotios Loupakis, et al. "Genetic variants involved in the lipid metabolism pathway to predict outcome in patients (pts) with metastatic colorectal cancer (mCRC): Data from FIRE-3 and MAVERICC trials." Journal of Clinical Oncology 39, no. 3_suppl (2021): 118. http://dx.doi.org/10.1200/jco.2021.39.3_suppl.118.

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118 Background: Antiangiogenic drug (AAD)-triggered oxygen and nutrient depletion through suppression of angiogenesis switches the glucose-dependent metabolism to lipid-dependent metabolism. Blocking fatty acid oxidation can enhance AAD-mediated anti-tumor effects in colorectal cancer. Previous reports suggested that polymorphisms of the lipid metabolism-related genes are associated with the increased risk of CRC and poor clinical outcome in CRC. Therefore, we hypothesized that genetic variants in the lipid metabolism pathway may predict first-line treatment outcome in mCRC pts. Methods: Genom
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Modest, Dominik P., Sebastian Stintzing, Ludwig Fischer von Weikersthal, et al. "Impact of Subsequent Therapies on Outcome of the FIRE-3/AIO KRK0306 Trial: First-Line Therapy With FOLFIRI Plus Cetuximab or Bevacizumab in Patients With KRAS Wild-Type Tumors in Metastatic Colorectal Cancer." Journal of Clinical Oncology 33, no. 32 (2015): 3718–26. http://dx.doi.org/10.1200/jco.2015.61.2887.

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Purpose We investigated choice and efficacy of subsequent treatment, with special focus on second-line therapy, in the FIRE-3 trial (FOLFIRI plus cetuximab [arm A] or bevacizumab [arm B]) for patients with KRAS wild-type metastatic colorectal cancer. Patients and Methods Start of subsequent-line (second or third) therapy was defined as use of an antitumor drug that was not part of the previous regimen. We evaluated choice, duration, and efficacy of subsequent therapy and determined the impact of subsequent-line treatment on outcome of patients in FIRE-3. Results Of 592 patients in the intent-t
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Rizal Mi’raz, Ade Irma Wantini, and Ganis Sanhaji. "Internet of Things Menggunakan Platform Realtime Data base Berbasis Aplikasi Android dan Google Voice Asistant untuk Alarm Anti Begal." TEMATIK 10, no. 1 (2023): 34–40. http://dx.doi.org/10.38204/tematik.v10i1.1288.

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 Recently there have been many cases of spoliation and motorbike theft in various cities throughout Indonesia. Spoliation occurs regardless of time and place. One of the preventive efforts is to create a system that can improve the motorcycle security system by using the Internet of Things (IoT). This article will discuss the use of IoT technology to help the safety and security of motorists, as well as motorbikes by designing an anti-theft alarm prototype. This alarm has the intelligence to force perpetrators of motorcycle robbery or theft to thwart their actions with vibration
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Modest, Dominik Paul, Sebastian Stintzing, Ludwig Fischer von Weikersthal, et al. "Time-course evaluation of survival and treatment in FIRE-3 (AIO KRK0306, first-line therapy of KRAS wild-type metastatic colorectal cancer with FOLFIRI plus cetuximab or bevacizumab)." Journal of Clinical Oncology 34, no. 4_suppl (2016): 617. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.617.

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617 Background: FIRE-3 reported overall survival (OS) difference in favour of arm A (FOLFIRI plus cetuximab, N= 297 pts.) compared to arm B (FOLFIRI plus bevacizumab, N= 295 pts.) in the absence of significant differences in progression-free survival and response rate. Methods: We subdivided the study into six-month time intervals, starting at the time point of randomisation and evaluated OS in a time-wise fashion. Within each interval, OS was analyzed by Cox regression. Furthermore, systemic treatment and local interventions were investigated in the respective time-frames. Results: The time-c
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Yamazaki, Kentaro, Yuriko Takeda, Toshihiro Misumi, et al. "Optimal molecular-targeted therapies as first-line treatment for RAS wild-type, right-sided metastatic colorectal cancer from the Analysis and Research in Cancers of the Digestive System (ARCAD) database." Journal of Clinical Oncology 41, no. 16_suppl (2023): 3588. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.3588.

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3588 Background: Although anti-EGFR antibody plus doublet chemotherapy has become the standard of first-line treatment for RAS wild-type (wt), left sided metastatic colorectal cancer (mCRC), the optimal molecular-targeted therapy for RAS wt, right-sided mCRC is not clear. Methods: To evaluate the efficacy between anti-EGFR antibody vs. bevacizumab combination therapy, from 40,889 Individual patient (pt) data from 59 studies in ARCAD mCRC database, 723 pts with RAS wt, right-sided mCRC who received a first-line molecular-targeted therapy with backbone chemotherapy (FOLFOX/FOLFIRI when anti-EGFR
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Гойкалов, Г. Г., А. А. Абашкин, Д. В. Ушаков, and С. Г. Панфилов. "Issues of ensuring timely evacuation of people from buildings of educational organizations." Pozharnaia bezopasnost`, no. 3(104) (October 5, 2021): 71–79. http://dx.doi.org/10.37657/vniipo.pb.2021.28.94.008.

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Статья посвящена проблеме противопожарной защиты объектов просвещения с учетом требований Федерального закона «Технический регламент о требованиях пожарной безопасности», постановления Правительства Российской Федерации, которым утверждены Правила проведения расчетов по оценке пожарного риска. Рассмотрены вопросы определения необходимого времени эвакуации людей из общеобразовательных организаций при пожаре. Проанализированы требования нормативных правовых документов в области пожарной безопасности. The article is devoted to the actual topic of providing conditions for the safe evacuation of pe
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Гойкалов, Г. Г., А. А. Абашкин, Д. В. Ушаков, and С. Г. Панфилов. "Issues of ensuring timely evacuation of people from buildings of educational organizations." Pozharnaia bezopasnost`, no. 3(104) (October 5, 2021): 71–79. http://dx.doi.org/10.37657/vniipo.pb.2021.28.94.008.

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Статья посвящена проблеме противопожарной защиты объектов просвещения с учетом требований Федерального закона «Технический регламент о требованиях пожарной безопасности», постановления Правительства Российской Федерации, которым утверждены Правила проведения расчетов по оценке пожарного риска. Рассмотрены вопросы определения необходимого времени эвакуации людей из общеобразовательных организаций при пожаре. Проанализированы требования нормативных правовых документов в области пожарной безопасности. The article is devoted to the actual topic of providing conditions for the safe evacuation of pe
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Kim, Teak-Keon, Seul-Kee Kim, and Jae-Myung Lee. "Dynamic Response of Drill Floor Considering Propagation of Blast Pressure Subsequent to Blowout." Applied Sciences 10, no. 24 (2020): 8841. http://dx.doi.org/10.3390/app10248841.

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Explosions and fire have very critical safety hazard impacts on offshore oil and gas facilities since they are mostly located in remote areas and could induce serious environmental issues. Explosion risk assessment and structure blast analysis are essential for these production facilities, and research studies have been carried out. Explosion due to blowout during drilling operation is also a critical risk for drilling units, and this has not been researched much until the accident of the drilling unit in the Gulf of Mexico in 2010. This paper provides the risk and evaluation of explosion and
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Dissertations / Theses on the topic "Anti fire hazard"

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Gregory, Bolotov, Болотов Григорій Іванович, Болотов Григорий Иванович, et al. "Problems and anti fire hazard fire resistance of high-rise buildings." Thesis, НАУ, 2017. http://er.nau.edu.ua/handle/NAU/28277.

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Considered structuring of existing approaches to solving problems in combating fire hazards and fire high-rise buildings, resistance to progressive collapse of buildings that justified tendency security construction projects for people and the environment. Ensuring trouble-free operation of existing and construction of tall buildings requires the ability to predict their behavior in the event of an emergency (partial loss of the bearing capacity, fire, earthquake and etc).
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Conference papers on the topic "Anti fire hazard"

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Zhang, Xueshuang, Li Fan, Lijian Cai, and Qianwen Liu. "Study on Protection Against Large Commercial Aircraft Crash of HPR1000." In 2018 26th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/icone26-81397.

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Protection against large commercial aircraft crash is a new design requirement for international advanced nuclear power plants, and gradually becomes one of important advance characteristics. The study follows the principle of balance of safety, economy, and mature achievable engineering technology, conducted by design extension condition and realistic analysis inapplicable to single failure criterion, adopts Anti-Plane Crash (APC) shell protection + redundant features physical isolation to fulfill the safety acceptance criteria, and results in the HPR1000 design scheme withdraw large commerci
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