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1

Graham, Ian, Therese Cooney, and Dirk De Bacquer. Risk stratification and risk assessment. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656653.003.0005.

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Cardiovascular disease (CVD) is the biggest cause of death worldwide. The underlying atherosclerosis starts in childhood and is often advanced when it becomes clinically apparent many years later. CVD is manageable: in countries where it has reduced this is due to changes in lifestyle and risk factors and to therapy. Risk factor management reduces mortality and morbidity. In apparently healthy people CVD risk is most frequently the result of multiple interacting risk factors and a risk estimation system such as SCORE can assist in making logical management decisions. In younger people a low ab
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2

Krochmal, Robert. Nutritional Support and Addiction. Edited by Shahla J. Modir and George E. Muñoz. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190275334.003.0017.

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Nutrition occupies a central position in the treatment of SUDs. Given the paradox that food can have apparently opposing effects in either causing addiction or in influencing its remedy, it is important to clarify this difference. Evidence is mounting that diseases such as obesity, heart disease, diabetes, and mental health disorders including addiction have a common root cause related to the increase in sugar and processed food consumption rather than fat consumption as has been commonly held. In addition to new integrative approach models encompassing a holistic perspective, new developments
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3

Mahon, Anthony D. Aerobic training. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199232482.003.0039.

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Aerobic training is defined as exercise training that involves whole body endurance activity that is sustained for a sufficient length of time and at a sufficient intensity in order to improve cardiorespiratory fitness.1 The effect of aerobic training on physiological function in children has been investigated for nearly four decades. Some of this research has focused on the health-related benefits of this type of training on children and adolescents and for good reason. With increasing rates of obesity, type 2 diabetes, metabolic syndrome, and many other physical inactivity-related disorders,
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4

Hage, Fadi G., Ayman Farag, and Gilbert J. Zoghbi. Screening Asymptomatic Subjects. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0016.

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Cardiovascular disease is the leading cause of death in the United States and accounts for more deaths than all cancers combined. Many apparently healthy adults first present to the health system with a myocardial infarction or sudden cardiac death. It is therefore imperative to assess the risk of cardiovascular events among currently asymptomatic individuals to try and intervene early in the disease process to prevent future events. Risk factors for the development of coronary artery disease in particular, and cardiovascular disease in general, have been identified from epidemiological studie
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5

Ferreira, Isabel, and Jos WR Twisk. Physical activity, cardiorespiratory fitness, and cardiovascular health. Edited by Neil Armstrong and Willem van Mechelen. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198757672.003.0017.

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It is now recognized that cardiovascular disease (CVD) is partly a paediatric problem, i.e. the onset begins in childhood, although clinical symptoms may not become apparent until later in life. Therefore, from a primary prevention point of view, the extent to which physical activity or physical fitness in childhood may deter this process is of utmost importance. Although physical activity and CRF at a young age have not been directly linked to the incidence of CVD, evidence thus far supports cardiovascular health benefits of early higher physical activity and CRF levels on cardiometabolic ris
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6

Currow, David C., and Stein Kaasa. Policy in palliative care. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0004.

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Hospice and palliative care services have developed in very different ways around the world. Most have been built on the momentum of visionary clinicians and funders who have responded to perceived needs from health-care providers, patients, families, and communities rather than in response to well-formed national policies with an adequately funded planning and development phase. This chapter describes the work that is being done at pan-national, national, and sub-national levels to create effective policies that can further the key work of hospice/palliative care, often after a large number o
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7

Thielman, Samuel B., and Glenn Goss. Ethical Considerations for Mental Health Providers Responding to Disasters and Emergencies. Edited by John R. Peteet, Mary Lynn Dell, and Wai Lun Alan Fung. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190681968.003.0019.

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Ethical considerations in psychiatry may have spiritual dimensions that are not always apparent to mental health providers. The ethical issues faced by responders to disasters and emergencies can be particularly thorny because ethical guidelines from professional bodies frequently do not address particular situations that arise in disaster settings. This chapter discusses the issue of dual agency in disaster situations. It also addresses concerns about psychiatric competencies in disaster response, especially where no guidelines exist. It addresses concerns raised by the need for documentation
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8

Carmona, Richard H., and Mark Liponis, eds. Integrative Preventive Medicine. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190241254.001.0001.

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As the preventable disease and economic burden continues to mount for the United States and the world, it is becoming apparent that embracing prevention strategies is essential. Simply continuing on the same course and infrastructure will not suffice. The future we will leave our children is unsustainable without change. Amid all the partisan political chaos, integrative preventive medicine (IPM) practices are strongly entering the public consciousness, as many are dissatisfied with their traditional health (sick) care delivery systems and the scientific validity of IPM is increasing rapidly.
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9

Sprouse, Adrienne. Toxins (DRAFT). Edited by Madeleine M. Castellanos. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190225889.003.0010.

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This chapter describes the categories of 300+ environmental chemicals measured in the blood and urine of Americans by the US Centers for Disease Control and Prevention. Some are endocrine-disrupting chemicals (EDCs) and substitute for endogenous hormones in a variety of metabolic processes affecting sexual health, obesity, diabetes, and behavior. The Monotonic Dose-Response (linear dose-response) is inappropriate when evaluating the health consequences of EDCs. Nonmonotonic Dose-Response Curves are better for considering the affinity of the ligand for the receptor, receptor saturation, ligand
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10

Trautmann, Sebastian, and Hans-Ulrich Wittchen. Trauma and PTSD in Europe. Edited by Charles B. Nemeroff and Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0008.

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The chapter gives an overview about the epidemiological studies of traumatic events and post-traumatic stress disorder (PTSD) in European countries with a focus on data from recent cross-national research initiatives. About two-thirds of the European population have experienced at least one traumatic event in their lifetime. Between 1% and 3% of the European population, however, have developed PTSD suffering from symptoms during the past year; this corresponds to about 7.7 million people. The PTSD prevalence varies considerably between European countries, with differences regarding trauma expo
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11

First, Michael B. Factors in the development of psychiatric epidemics. Edited by Kenneth S. Kendler and Josef Parnas. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198796022.003.0017.

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The term “epidemic” is broadly employed to refer to any occurrence of illness that is clearly in excess of normal expectancy. Whenever there is an apparent increase in the number of cases over a relatively short time, there are three possibilities: (1) a true epidemic in which the actual incidence of the disorder is increasing; (2) an increase in the number of previously undiagnosed individuals coming to clinical attention; or (3) a broadening of diagnostic definitions over time. Although reports of greatly increased rates of some psychiatric disorders in the past 30 years suggest possible “ep
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12

Lippmann, Morton, and Richard B. Schlesinger. Introduction and Historical Perspective. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190688622.003.0001.

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Literature relevant to chemical contamination, especially to the adverse effects of occupational exposures, extends back to ancient Greece, Middle Age Europe and Japan, and the dawn of the industrial age. For air pollution, the adverse effects of coal burning effluents were recognized in London in the thirteenth century and became acute over 150 years ago. The feasibility of control of drinking water pollution due to communicable diseases agents was not adequately demonstrated until early in the twentieth century. By the middle of the twentieth century, it became apparent that chemical contami
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13

Haunton, Victoria, Aung Sett, Amit Mistri, and Martin Fotherby. Stroke. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0227.

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The World Health Organization defines stroke as ‘a clinical syndrome consisting of rapidly developing clinical signs of focal (at times global) disturbance of cerebral function lasting greater than 24 hours (or leading to death) with no apparent cause other than that of vascular origin’. Transient ischaemic attack (TIA) is defined as a rapid presentation of neurological deficit with complete recovery within 24 hours of the onset of symptoms. However, the 24-hour cut-off is arbitrary, has no biological basis, and is of limited use clinically. A shorter duration is now regarded as more appropria
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14

Bashford, Alison, and Philippa Levine, eds. The Oxford Handbook of the History of Eugenics. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195373141.001.0001.

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The Oxford Handbook of the History of Eugenics covers the nineteenth century to the post-World War II era and dispels for uninitiated readers the automatic and apparently exclusive link between eugenics and the Holocaust. It provides a world history of eugenics. Eugenic thought and practice swept the world from the late nineteenth to the mid-twentieth century in a remarkable transnational phenomenon. Eugenics informed social and scientific policy across the political spectrum, from liberal welfare measures in emerging social-democratic states to feminist ambitions for birth control, from publi
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15

Letheby, Chris. Philosophy of Psychedelics. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198843122.001.0001.

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Philosophy of Psychedelics is the first scholarly monograph in English devoted to the philosophical analysis of psychedelic drugs. Its central focus is the apparent conflict between the growing use of psychedelics in psychiatry and the philosophical worldview of naturalism, which holds that the natural world is all that exists. The book reviews scientific evidence that psychedelics such as lysergic acid diethylamide (LSD) and psilocybin can be given safely in controlled conditions, and can cause lasting psychological benefits with one or two administrations. Supervised psychedelic sessions can
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