Academic literature on the topic 'Autoimmune Uveitis'

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Journal articles on the topic "Autoimmune Uveitis"

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Verma, Ashutosh, S. R. Rathinam, C. Gowri Priya, V. R. Muthukkaruppan, Brian Stevenson, and John F. Timoney. "LruA and LruB Antibodies in Sera of Humans with Leptospiral Uveitis." Clinical and Vaccine Immunology 15, no. 6 (2008): 1019–23. http://dx.doi.org/10.1128/cvi.00203-07.

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ABSTRACT Uveitis can be a serious complication of leptospirosis. Previous studies indicated that the leptospiral lipoproteins LruA and LruB are expressed in the eyes of uveitic horses and that antibodies directed against those proteins show in vitro cross-reactivity with components of equine lens, ciliary body, and/or retina. We now demonstrate that sera from a significant proportion of humans who have leptospiral uveitis also contain antibodies against LruA and LruB. Different categories of nonleptospiral uveitis and autoimmune uveitis were also screened; patients diagnosed with Fuchs uveitis
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Lorenz, Lea, Barbara Amann, Sieglinde Hirmer, Roxane L. Degroote, Stefanie M. Hauck, and Cornelia A. Deeg. "NEU1 is more abundant in uveitic retina with concomitant desialylation of retinal cells." Glycobiology 31, no. 7 (2021): 873–83. http://dx.doi.org/10.1093/glycob/cwab014.

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Abstract Desialylation of cell surface glycoproteins carried out by sialidases affects various immunological processes. However, the role of neuraminidase 1 (NEU1), one of the four mammalian sialidases, in inflammation and autoimmune disease is not completely unraveled to date. In this study, we analyzed the retinal expression of NEU1 in equine recurrent uveitis (ERU), a spontaneous animal model for autoimmune uveitis. Mass spectrometry revealed significantly higher abundance of NEU1 in retinal Müller glial cells (RMG) of ERU-diseased horses compared to healthy controls. Immunohistochemistry u
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Plekhanov, A. N., A. S. Fomina, O. P. Sverkunova, and J. V. Ivanova. "Autoimmune Uveitis. Review." Ophthalmology in Russia 16, no. 1 (2019): 5–11. http://dx.doi.org/10.18008/1816-5095-2019-1-5-11.

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For many years in ophthalmology there is a complex intractable problem associated with inflammation of the vascular membrane of the eye, the so-called uveitis. Experts around the world are trying to understand this heterogeneous pathology of the visual organ, in a short time, which can lead to a sharp decrease in visual acuity, the development of severe complications and further disability. The number of patients with inflammation of the vascular tract is growing rapidly every year, the age is younger. The clinical picture of this pathology has changed slightly. Often began to manifest itself
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Commodaro, Alessandra Gonçalves, Luciana de Deus Vieira de Moraes, Denise Vilarinho Tambourgi, Rubens Belfort Jr., Osvaldo Augusto Sant’Anna, and Luiz Vicente Rizzo. "Autoimmune uveitis: study of treatment therapies." Einstein (São Paulo) 8, no. 1 (2010): 117–21. http://dx.doi.org/10.1590/s1679-45082010rb1416.

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ABSTRACT Experimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues. Inflammation in experimental autoimmune uveitis may be induced in rodents by immunization with retinal antigens, such as interphotoreceptor retinoid-binding protein. We present a review of experimental studies that correlate primary immunobiological functions with this chronic disease and the possible use of molecules for the treatment of autoimmune uveitis.
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Muntean, Laura, and Simona Rednic. "TREATMENT OF UVEITIS ASSOCIATED WITH SYSTEMIC AUTOIMMUNE DISEASES IN ADULTS: A CONCISE OVERVIEW." Romanian Journal of Rheumatology 26, no. 4 (2017): 154–59. http://dx.doi.org/10.37897/rjr.2017.4.3.

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Uveitis represents a heterogenous group of inflammatory ocular diseases which may cause vision loss. Association of uveitis with arthritis may occur in many systemic autoimmune diseases, including spondyloarthritis, juvenile idiopathic arthritis, Behҫet’s disease and sarcoidosis. Recent advances in the field of autoimmune diseases have provided new insights and developments of diverse therapies for noninfectious uveitis. However, the optimal treatment strategy for patients with uveitis remains to be defined. Topical and/or systemic corticosteroids are the first-line therapy of autoimmune uveit
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Alawneh, Khaldoon M., Omar A. Saleh, Mahmoud M. Smadi, et al. "Pattern of Uveitis in a Tertiary Hospital in North Jordan and the Impact of Behcet’s Disease." Journal of Ophthalmology 2023 (August 8, 2023): 1–6. http://dx.doi.org/10.1155/2023/2076728.

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Aim. The purpose of this study is to assess the prevalence of autoimmune-mediated uveitis in relation to other diseases and to describe the clinical patterns of uveitis in a single tertiary hospital in north Jordan. Methods. A cross-sectional retrospective review was performed. We included all patients diagnosed with uveitis in King Abdullah University Hospital (KAUH) ophthalmology clinic and/or patients referred to KAUH rheumatology clinics for evaluation of suspected autoimmune mediated uveitis or for difficult to treat uveitis. This included patients from January 2015 to January 2019. Data
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Ruggieri, Simona, Maria Antonia Frassanito, Rosanna Dammacco, and Silvana Guerriero. "TregLymphocytes in Autoimmune Uveitis." Ocular Immunology and Inflammation 20, no. 4 (2012): 255–61. http://dx.doi.org/10.3109/09273948.2012.681830.

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Horai, Reiko, and Rachel R. Caspi. "Cytokines in Autoimmune Uveitis." Journal of Interferon & Cytokine Research 31, no. 10 (2011): 733–44. http://dx.doi.org/10.1089/jir.2011.0042.

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WHITCUP, SCOTT M., and ROBERT B. NUSSENBLATT. "Treatment of Autoimmune Uveitis." Annals of the New York Academy of Sciences 696, no. 1 (2006): 307–18. http://dx.doi.org/10.1111/j.1749-6632.1993.tb17166.x.

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Caspi, Rachel R. "Mechanisms Underlying Autoimmune Uveitis." Drug Discovery Today: Disease Mechanisms 3, no. 2 (2006): 199–206. http://dx.doi.org/10.1016/j.ddmec.2006.05.006.

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Dissertations / Theses on the topic "Autoimmune Uveitis"

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Dua, Harminder Singh. "Immunomodulation of experimental autoimmune uveitis." Thesis, University of Aberdeen, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317710.

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Chronic posterior uveitis is a relatively common clinical disorder and an importance cause of visual impairment in young adults. Experimental autoimmune uveitis (EAU) and its associated experimental autoimmune pinealitis (EAP) induced by retinal autoantigens are predominantly CD4+ T cell mediated (auto) immune disease of the retina and uveal tract of the eye and the pineal gland respectively. EAU bears a close clinical and pathological resemblance to chronic posterior uveitis in humans and seves as a good animal model for the study of posterior uveitis. The EAU model was used to study means of
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Minas, Konstantinos. "New approaches to autoimmune therapy through gene analysis." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources. Restricted no access until May 19, 2011. Online version available for University member only until May 19, 2012, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25620.

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Read, Russell W. "The role of complement in experimental autoimmune uveitis." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. https://www.mhsl.uab.edu/dt/2007p/read.pdf.

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Morgan, James. "Analysis of candidate retinal autoantigens in autoimmune uveitis." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415718.

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Zhao, Zi-Shan. "T cell effector mechanisms in experimental autoimmune uveitis (EAU)." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294788.

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Klaska, Izabela. "Dendritic cell-based therapy of experimental autoimmune uveoretinitis." Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=196130.

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Recently, there has been considerable interest in developing specific cell-based immunotherapies using dendritic cells (DCs). Here the mechanisms underlying the tolerogenic properties of DCs in the suppression of experimental autoimmune uveoretinitis (EAU), the mouse model of human sight threatening autoimmune uveitis, were examined. Immature DCs have the ability to promote immune tolerance to self antigens and to prevent the development of autoimmune disorders including EAU. However there is a risk that immature DCs placed in the inflammatory environment would undergo maturation and instead o
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Hoey, Sharon. "Cytokine-induced nitric oxide mediates tissue damage in experimental autoimmune uveitis." Thesis, University of Aberdeen, 1999. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602036.

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The large amounts of nitric oxide (NO) produced by the inducible nitric oxide synthase (iNOS) has been described as a double-edged sword eliciting pro- or anti inflammatory effects in different immune situations. The aim of this study was to investigate the role of NO in ocular inflammation. Rat RPE cells were shown to produce NO in vitro in response to inflammatory stimuli but in vivo the RPE expressed little or no iNOS enzyme in the normal Lewis rat eye. However, expression of the iNOS enzyme was closely associated with disease activity in experimental autoimmune uveoretinitis (EAU), a model
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Kaufmann, Ulrike. "Immunoregulation of monophasic and relapsing experimental autoimmune uveitis in the rat model." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-176686.

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Kaufmann, Ulrike [Verfasser], and Gerhild [Akademischer Betreuer] Wildner. "Immunoregulation of monophasic and relapsing experimental autoimmune uveitis in the rat model / Ulrike Kaufmann. Betreuer: Gerhild Wildner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/106287739X/34.

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Greiner, Kathrin Heike. "Medical treatment of autoimmune uveitis : clinical and laboratory investigations into new therapies for non-infectious posterior segment intraocular inflammation." Thesis, University of Aberdeen, 2004. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU486816.

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The studies in this thesis were aimed at developing new treatment concepts for PSII based on the understanding of the immunological mechanisms characterised in basic research. The intensity and prognosis of inflammatory disease determine the intensity of immunosuppressive therapy. In addition to clinical features, markers of effective immunosuppression are required to guide the immunosuppressive treatment in PSII patients, especially in those patients with opaque media. A secondary aim of this thesis was, hence, the evaluation of laboratory markers, notably CD4+ T cell phenotype markers, for t
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Books on the topic "Autoimmune Uveitis"

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Haghighi, Afshin Borhani, and Bernadette Kalman. Other Proven and Putative Autoimmune Disorders of the CNS. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0094.

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Behcet’s Disease (BD) is a multiorgan disorder characterized by oral and genital ulceration, uveitis, and dermatological symptoms. BD is most prevalent in the Mediterranean countries and East Asia, but also occurs in Europe and North America. The etiology remains unknown. Evidence suggests that BD is an autoimmune disorder with complex traits. Neuro-Behcet’s Syndome (NBS) develops in about 5% to 30% of patients with BD and presents with parenchymal or nonparenchymal pathology. The course of NBS is highly variable. Treatment strategies include modulations of the immune response and tissue degen
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Segall, Liviu, and Adrian Covic. Immune-mediated tubulointerstitial nephritis. Edited by Adrian Covic. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0093_update_001.

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Immune-mediated tubulointerstitial nephritides (TINs) are generally encountered in the context of systemic or extrarenal autoimmune diseases, such as sarcoidosis, Sjögren syndrome, systemic lupus erythematosus, inflammatory bowel disease, TIN and uveitis (TINU) syndrome, and immunoglobulin G4-related disease. The pathogenesis of these TINs is complex and more or less unclear; it usually involves leucocyte activation, autoantibodies, immune complex deposition, complement activation, and release of inflammatory cytokines and growth factors. Tubulointerstitial inflammation most commonly has a chr
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Book chapters on the topic "Autoimmune Uveitis"

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de Andrade, Francisco Assis, Ivan Foeldvari, and Roger A. Levy. "Autoimmune Uveitis." In Diagnostic Criteria in Autoimmune Diseases. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-285-8_85.

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Adán, Alfredo. "Autoimmune Uveitis." In Autoimmune Disease Diagnosis. Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-69895-8_93.

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Armbrust, Karen R., Maggie M. Wei, Brett G. Jeffrey, and H. Nida Sen. "Autoimmune Retinopathy." In The Uveitis Atlas. Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-2410-5_104.

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Armbrust, Karen R., Maggie M. Wei, Brett G. Jeffrey, and H. Nida Sen. "Autoimmune Retinopathy." In The Uveitis Atlas. Springer India, 2016. http://dx.doi.org/10.1007/978-81-322-2506-5_104-1.

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Wildner, G., and S. R. Thurau. "Oral Tolerance in Autoimmune Uveitis." In Uveitis Update. KARGER, 1999. http://dx.doi.org/10.1159/000060757.

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Zhang, Meifen, and Bo Wan. "Uveitis and Autoimmune Diseases." In Integrative Ophthalmology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7896-6_31.

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Huang, Zhaohao, Wenli Li, and Wenru Su. "Tregs in Autoimmune Uveitis." In Advances in Experimental Medicine and Biology. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-6407-9_11.

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Kielczewski, Jennifer L., and Rachel R. Caspi. "Animal Models of Autoimmune Uveitis." In Animal Models of Ophthalmic Diseases. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19434-9_6.

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Nussenblatt, Robert B. "Immune Therapy for Autoimmune Uveitis." In Immunopharmacology in Autoimmune Diseases and Transplantation. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4899-1167-4_26.

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Agarwal, Rajeev K., Phyllis B. Silver, and Rachel R. Caspi. "Rodent Models of Experimental Autoimmune Uveitis." In Methods in Molecular Biology. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-60761-720-4_22.

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Conference papers on the topic "Autoimmune Uveitis"

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Silva, Vitória Pimentel da, Lucas Immich Gonçalves, Giordani Rodrigues dos Passos, Maísa Kappel, Mayumi Charão, and Jefferson Becker. "Vogt-Koyanagi-Harada Syndrome: case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.637.

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Context: Red eye complaints are common in medical practice. Trauma, infection and autoimmune disorders are possible causes. It is essential to diagnose early to avoid sequelae. Case report: Female, 58 years old, 30 days of progression of bilateral frontal and retro-orbital headache associated with red eye and decreased visual acuity in both eyes, otalgia and tinnitus in the left ear. No trauma history. She started treatment in another hospital with acyclovir for suspected viral meningitis and was referred for evaluation after 10 days due to the lack of improvement. In our evaluation, the patie
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Schnabel, Anja, Elisabeth Unger, Normi Bruck, et al. "FRI0574 CLINICAL RESPONSE TO HIGH-DOSE INTRAVENOUS METHYLPREDNISOLONE IN CHILDHOOD AUTOIMMUNE UVEITIS: A RETROSPECTIVE ANALYSIS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.2495.

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Cezar Araujo, Leticia, Fernanda Lourenço Macagnani, Camila Ávila Megda Cabianca, et al. "Do we need immunobiologic drugs for treating autoimmune anterior uveitis in a tertiary referral center?" In SBR 2021 Congresso Brasileiro de Reumatologia. Sociedade Brasileira de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2021.1772.

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Teixeira, Rebecca Vieira, André Luiz Guimarães de Queiroz, Louis Fernando Marques de Almeida, Érico Induzzi Borges, Herval Ribeiro Soares Neto, and Sônia Maria Cesar de Azevedo Silva. "Adalimumab treatment in a patient with severe presentation of VogtKoyanagi-Harada." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.491.

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Context: Vogt-Koyanagi-Harada syndrome (VKH) is a rare, multisystemic, autoimmune disease mediated by a Th1 response against melanocytes in the eye, inner ear, central nervous system, skin and hair. In this article, we report a case of VKH with severe visual impairment and discuss the therapeutic response to corticotherapy followed by the use of Adalimumab, a tumor necrosis factor (TNFα) inhibitor. Case report: A 61-year-old black woman started bilateral frontal headache of severe intensity, associated with bilateral eye pain, hyperemia and watery eyes, progressing with visual turbidity with g
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