Academic literature on the topic 'Autopsy brain'

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Journal articles on the topic "Autopsy brain"

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Swerdlow, Russell H., Mony J. de Leon, and David L. Marcus. "Betahydroxybutyrate Consumption in Autopsy Brain Tissue from Alzheimer’s Disease Subjects." Journal of Alzheimer's Disease Reports 5, no. 1 (2021): 135–41. http://dx.doi.org/10.3233/adr-210002.

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Background: Alzheimer’s disease (AD) features perturbed brain glucose utilization, which could contribute to brain bioenergetic failure. This led some to consider using ketone bodies to enhance AD brain bioenergetics and treat AD. Objective: We evaluated the rate at which brain homogenates from persons with Alzheimer’s disease (AD) metabolize D-β-hydroxybutyrate (BHB). Methods: We homogenized pieces of temporal cortex from frozen autopsy brains obtained from recently deceased AD subjects (n = 4), and age-matched subjects that did not have clinical AD (n = 3). Measuring the rate of CO2 producti
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Kibayashi, Kazuhiko, Paul M. Ng’walali, Martin P. Mbonde, et al. "Neuropathology of Human Immunodeficiency Virus 1 Infection." Archives of Pathology & Laboratory Medicine 123, no. 6 (1999): 519–23. http://dx.doi.org/10.5858/1999-123-0519-nohivi.

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Abstract Objective.—In sub-Saharan Africa, only a few studies of neurologic complications of human immunodeficiency virus 1 (HIV-1) infection have been done. The authors studied neuropathology of HIV-1 infection in Tanzania. Design.—Forensic autopsy study at Dar es Salaam, Tanzania. Setting.—A joint research project between Dar es Salaam, Tanzania, and Kumamoto, Japan. Patients.—Thirty patients with risk factors for HIV-1 infection. Main Outcome Measures.—Human immunodeficiency virus 1 infection was evaluated by HIV-1 antibody test on postmortem serum samples. The brains of HIV-1–infected pers
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Salami, A., M. Ajani, I. Orhorho, et al. "Brain weights in adult africans." Journal of Morphological Sciences 34, no. 04 (2017): 223–25. http://dx.doi.org/10.4322/jms.106316.

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Abstract Introduction: The average brain weight of adult humans, using Caucasian figures, is said to be between 1300g to 1400g. Few studies have however been done to make actual evaluations of brain weights in adult Africans. This study seeks to examine the weight of brains from people of African descent with respect to variations in sex and age in decades using autopsy specimens. Materials and Methods: Analysis of the weight of brains removed from both male and female adult patients during fresh autopsy of their bodies in our center over a ten year period was done. The study criteria required
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Kandel, Jwala, and Dikshanta Pokharel. "Mean Brain Weight among Autopsy Cases at the Department of Forensic Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study." Journal of Nepal Medical Association 60, no. 247 (2022): 274–77. http://dx.doi.org/10.31729/jnma.7162.

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Introduction: Weight of the brain is an important diagnostic criterion during autopsy. Normal variations in brain weight among various population demands for population-specific study. The aim of this study was to find the mean brain weight among autopsy cases at a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among autopsy cases in the Department of Forensic Medicine of a tertiary care hospital from July 2019 to July 2021. The approval for the study was obtained from the Institutional Review Committee (Reference number: 550/2019). Convenience sampling was do
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Klinken, L., and P. Arlien-Søborg. "Brain autopsy in organic solvent syndrome." Acta Neurologica Scandinavica 87, no. 5 (2009): 371–75. http://dx.doi.org/10.1111/j.1600-0404.1993.tb04120.x.

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Provias, John, and Brian Jeynes. "Immunohistochemical Detection of Receptor-Associated Protein in Normal Human Brain and Alzheimer's Disease." Pathology Research International 2010 (December 20, 2010): 1–5. http://dx.doi.org/10.4061/2010/173496.

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This study is one of the few to characterize immunohistochemically the distribution and localization of Receptor-Associated Protein (RAP) in human autopsy brain. The results show prominent cortical neuronal localization. RAP is clearly identified in large neuronal dendritic/axonal processes. RAP is expressed in both large pyramidal and smaller interneurons. Occasional, much less frequent RAP is detectable in glial cells in white matter, which appear to be predominantly astrocytic. Although RAP is detectable immunohistochemically in Alzheimer's disease autopsy brain, the level of expression app
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Carlos, Durão H., Veiga G. Marcos, Nina Pedro, Gonçalves M. Manuela, and Frederico Pedrosa. "Sudden death associated with melanoma brain metastases." Journal of Pathology of Nepal 8, no. 2 (2018): 1412–15. http://dx.doi.org/10.3126/jpn.v8i2.20896.

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A 48-year-old male Caucasian, with no relevant medical history except for a mild depression, was found by the partner, passed out on the bedroom floor. Since he was found in cardiac arrest, cardiopulmonary resuscitation was attempted, without success. Initially, it was suspected to be a suicide attempt and autopsy findings revealed coronary atherosclerosis of about 40%, with no other recoverable cardiac findings.The brain showed multiple probable neoplastic lesions, associated with cerebral and cerebellar hemorrhage. The primary tumor was not identified, but the victim had multiple cutaneous n
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Conces, Miriam R., Anna Hughes, and Christopher R. Pierson. "Neuropathology of Mowat–Wilson Syndrome." Pediatric and Developmental Pathology 23, no. 4 (2020): 322–25. http://dx.doi.org/10.1177/1093526620903956.

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Mowat–Wilson syndrome (MWS) is a syndromic form of Hirschsprung disease that is characterized by variable degrees of intellectual disability, characteristic facial dysmorphism, and a diverse set of other congenital malformations due to haploinsufficiency of ZEB2. A variety of brain malformations have been described in neuroimaging studies of MWS patients, and the role of ZEB2 in the brain has been studied in a multitude of genetically engineered mouse models that are now available. However, a paucity of autopsy information limits our ability to correlate data from neuroimaging studies and anim
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Sonnemans, Lianne J. P., Bela Kubat, Mathias Prokop, and Willemijn M. Klein. "Can virtual autopsy with postmortem CT improve clinical diagnosis of cause of death? A retrospective observational cohort study in a Dutch tertiary referral centre." BMJ Open 8, no. 3 (2018): e018834. http://dx.doi.org/10.1136/bmjopen-2017-018834.

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ObjectiveTo investigate whether virtual autopsy with postmortem CT (PMCT) improves clinical diagnosis of the immediate cause of death.DesignRetrospective observational cohort study. Inclusion criteria: inhospital and out-of-hospital deaths over the age of 1 year in whom virtual autopsy with PMCT and conventional autopsy were performed. Exclusion criteria: forensic cases, postmortal organ donors and cases with incomplete scanning procedures. Cadavers were examined by virtual autopsy with PMCT prior to conventional autopsy. The clinically determined cause of death was recorded before virtual aut
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Minami, Seigo, Hideyasu Okada, Shoichi Ihara, Hiromi Tsuji, Misaki Yamadera, and Hironao Yasuoka. "Pembrolizumab-Induced Meningoencephalitis: A Brain Autopsy Case." Journal of Medical Cases 12, no. 9 (2021): 359–65. http://dx.doi.org/10.14740/jmc3748.

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Dissertations / Theses on the topic "Autopsy brain"

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Ighodaro, Eseosa T. "STUDYING VASCULAR MORPHOLOGIES IN THE AGED HUMAN BRAIN USING LARGE AUTOPSY DATASETS." UKnowledge, 2018. https://uknowledge.uky.edu/neurobio_etds/19.

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Cerebrovascular disease is a major cause of dementia in elderly individuals, especially Black/African Americans. Within my dissertation, we focused on two vascular morphologies that affect small vessels: brain arteriolosclerosis (B-ASC) and multi-vascular profiles (MVPs). B-ASC is characterized by degenerative thickening of the wall of brain arterioles. The risk factors, cognitive sequelae, and co-pathologies of B-ASC are not fully understood. To address this, we used multimodal data from the National Alzheimer’s Coordinating Center, Alzheimer’s Disease Neuroimaging Initiative, and brain-banke
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Vera, Montecinos América. "Proteomic profile in postmortem brain in chronic schizopfrenia." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/673434.

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Schizophrenia is a complex psychiatric disorder involving dysregulation of multiple pathways. In the last decades, the cortico-cerebellar-thalamo-cortical circuit has been proposed to play a key role in cognitive impairments in schizophrenia. The cerebellum is a brain area that forms part of this circuit that modulates synaptic responses of cortical regions, it has been proposed to play an important role in schizophrenia pathophysiology. Furthermore, the cerebellum, in connection with the dorsolateral prefrontal cortex, is involved in executive and working memory function. Thus, we hypothesize
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Abboud, Sherine. "Susceptibility genes in ischemic stroke and intracranial atherosclerosis: clinical and autopsy studies." Doctoral thesis, Universite Libre de Bruxelles, 2009. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210290.

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Stroke is the third leading cause of death and the most common cause of disability in the world. To relieve the heavy burden of stroke, we need to understand the mechanisms that will form the basis of improved prevention and treatment. Epidemiological studies have found evidence for a genetic influence on the common form of stroke. However the genetic of stroke is still in its infancy. Subclinical intracranial atherosclerosis is sometime a predisposing factor for ischemic stroke (IS). This study was carried out to elucidate genetic factors influencing the complex phenotype of IS and subclinica
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SHIBAMOTO, YUTA, YOSHIMASA MORI, MASAMI ASAI, et al. "Gamma Knife Radiosurgery of Brain Metastasis from Malignant Pleural Mesothelioma : Report of Three Cases with Autopsy Study in a Case." Nagoya University School of Medicine, 2014. http://hdl.handle.net/2237/19497.

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Marutle, Amelia. "Neuronal nicotinic receptor subtypes in normal ageing, Alzheimer's disease and schizophrenia : influences of neuropathological mechanisms as studied in human autopsy brain and transgenic mice /." Stockholm : [Karolinska institutets bibl.], 2002. http://diss.kib.ki.se/2002/91-7349-133-0.

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Books on the topic "Autopsy brain"

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Dean, Brian, Joel E. Kleinman, and Thomas M. Hyde. Using CNS autopsy tissue in psychiatric research: A practical guide. Harwood Academic Publishers, 1999.

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Massimini, Marcello, and Giulio Tononi. A Brain in Your Hand. Translated by Frances Anderson. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198728443.003.0001.

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This chapter introduces the problem of the relationships between matter and consciousness by asking the reader to step in the shoes of a medical student who is given a human brain to hold during an autopsy. From this perspective, the brain is just another worldly object. A thing with mass and borders. How can this be? Holding a brain, feeling its texture and weight, must be like seeing the Earth from the Moon as a tiny blue dot. It is a sublime experience, and it is both a source of mental anguish and liberation. In this way, the reader is presented with basic scientific questions that have an
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Abel, E. Lawrence. A Finger in Lincoln’s Brain. ABC-CLIO, LLC, 2015. http://dx.doi.org/10.5040/9798400651434.

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This intriguing book examines Lincoln's assassination from a behavioral and medical sciences perspective, providing new insights into everything from ballistics and forensics to the medical intervention to save his life, the autopsy results, his compromised embalming, and the final odyssey of his bodily remains. In this book, E. Lawrence Abel sheds much-needed light on the fascinating details surrounding the death of Abraham Lincoln, including John Wilkes Booth's illness that turned him into an assassin, the medical treatment the president is alleged to have received after he was shot, and the
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Miletich, John J., and Tia Laura Lindstrom. An Introduction to the Work of a Medical Examiner. ABC-CLIO, LLC, 2010. http://dx.doi.org/10.5040/9798400672156.

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Medical examiners play an increasingly important role in society as unexpected and violent deaths increase, not only due to crime, but also due to new toxins in the environment, emerging diseases crossing from animals to humans, bizarre suicides, sadistic sexual practices, and other non-natural causes. John Miletich and Tia Lindstrom take us into the world of these medical detectives. Biological clues from bite marks and skin abnormalities to blood chemical levels and brain oxygenation are just some factors exposed in their quest for truth and justice. We learn the basics of death determinatio
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Book chapters on the topic "Autopsy brain"

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Zülch, Klaus J. "Autopsy Techniques." In Brain Tumors. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-68178-3_14.

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Mould, Richard F. "Autopsy on Lenin’s Brain." In Mould's Medical Anecdotes. Routledge, 2018. http://dx.doi.org/10.1201/9780203746448-278.

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Sugiyama, Kazuhiko, Asao Hirano, Josefina F. Llena, et al. "Incidental Meningiomas in Autopsy Cases in Computed Tomography and Magnetic Resonance Imaging Era." In Brain Tumor. Springer Japan, 1996. http://dx.doi.org/10.1007/978-4-431-66887-9_9.

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Gold, Gabriel, François Herrmann, Constantin Bouras, Eniko Kövari, and Aikaterini Xekardaki. "Decrease in Amyloid Deposition in Aging Brain—An Autopsy Study." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08939-3_5.

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Sonnen, Joshua A. "Autopsy Human Brain Dissection Protocol for Common Age-Related Neurodegenerative Disorders." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2409-8_16.

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Nagashima, Goro, R. Suzuki, J. I. Asai, M. Noda, M. Fujimoto, and T. Fujimoto. "Tissue reconstruction process in the area of peri-tumoural oedema caused by glioblastoma — immunohistochemical and graphical analysis using brain obtained at autopsy." In Brain Edema XII. Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-0651-8_104.

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Tasker, R. R., M. Yoshida, A. A. F. Sima, and J. Deck. "Stimulation Mapping of the Periventricular-Periaqueductal Gray (PVG-PAG) in Man — an Autopsy Study." In Surgery in and around the Brain Stem and the Third Ventricle. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71240-1_16.

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Fu, YuHong, Onur Tanglay, Hongyun Li, and Glenda M. Halliday. "The Role of Alpha-Synuclein Pathology." In Neuromethods. Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-4083-8_2.

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AbstractAlpha-synuclein (αSyn) is a conformationally flexible protein that is known to be involved in key neuronal biological processes and the pathogenesis of Parkinson’s disease (PD). The aggregation of αSyn in the brain is not only the neuropathological hallmark of PD but also characterizes other primary synucleinopathies, including dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). These disorders share common clinical motor symptoms, namely, parkinsonism, which is associated with the loss of nigral dopaminergic neurons. Pathologically the selective neurodegeneration in syn
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Rambeck, B., R. Schnabel, T. May, U. Jürgens, and R. Vlllagrán. "Distribution of Phenytoin in Different Regions of the Brain and in the Serum: Analysis of Autopsy Specimens from 25 Epileptic Patients." In Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology. CRC Press, 2023. http://dx.doi.org/10.1201/9781003418153-63.

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Croskerry, Pat. "The Misunderstood Matelot." In The Cognitive Autopsy, edited by Pat Croskerry. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190088743.003.0023.

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This case describes a pleasant, elderly naval veteran who presents to the emergency department on several occasions with some troubling symptoms that are of concern to his family. A consensus develops among his physicians that he is showing signs of dementia, probably due to organicity caused by a lifetime of drinking alcohol. Although he may have incurred some damage to his liver–brain axis through drinking alcohol, the true cause of his recent deterioration lies elsewhere.
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Conference papers on the topic "Autopsy brain"

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Janz, David R., Ty W. Abel, and Eugene W. Ely. "Neuropathological Abnormalities On Brain Autopsy Findings Of Previously Delirious ICU Patients." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6700.

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Qi, Lin, Baxter A. Patricia, Kogiso Mari, et al. "Abstract 1450: Autopsy derived orthotopic xenograft (ADOX) mouse models for terminal pediatric brain tumors." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1450.

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Belwadi, Aditya, and King H. Yang. "Near Side Lateral Impacts and Aortic Injury: A Parametric Study." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-54019.

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Traumatic rupture of the aorta (TRA) remains the second most common cause of death associated with motor vehicle crashes after brain injury. On an average, nearly 8,000 people die annually in the United States due to blunt injury to the aorta. It is observed that more than 80% of occupants who suffer an aortic injury die at the scene due to exsanguination into the chest cavity. TRA and blunt aortic injury (BAI) are leading causes of death in high-speed blunt impact trauma. More specific injuries that fall under these classifications include myocardial contusion (MC), traumatic aortic disruptio
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Wang, Chenzhi, Jae Bum Pahk, Carey D. Balaban, et al. "Biomechanical Assessment of the Bridging Vein Rupture of Blast-Induced Traumatic Brain Injury Using the Finite Element Human Head Model." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-88739.

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The incidence of the blast-induced traumatic brain injury (bTBI) among American troops in battle environments is dramatically high in recent years. Shock wave, a production of detonation, is a brief and acute overpressure wave that travels supersonically with a magnitude which can be several times higher than atmospheric pressure. Primary bTBI means that human exposure to shock wave itself without any other impact of solid objects can still result in the impairment of cerebral tissues. The mechanism of this type of brain injury is different from that of the conventional TBI, and has not been f
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Barbosa, Mateus Gonçalves de Sena, Ghaspar Gomes de Oliveira Alves Francisco, Rafaela Luiza Vilela de Souza, João Marcos Alcântara de Souza, and Nicollas Nunes Rabelo. "Chronic traumatic encephalopathy in military and sportsists: a factual problem?: a systematic review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.324.

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Background: Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to tau protein associated with recurrent brain trauma, clinically marked by mood, personality, cognitive and behavioral changes. Objectives: The objective of the study was to demonstrate whether athletes and military personnel can really be victims of CTE and to elucidate this same pathology. Design and setting: This is a systematic review, based on the PRISMA guidelines and a literature review with a summary of the evidence found. Methods: Articles were selected, published from 1934 to 2020, i
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SHEN, M. C., S. H. CHEN, and K. S. LIN. "TWO CASES OF NEONATAL PURPURA FULMINANS HOMOZYGOUS FOR PROTEIN C DEFICIENCY IN A CHINESE FAMILY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644308.

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Protein C (PC) deficiency associated with hereditary venous thromboembolic disease was first reported in 1981 and is inherited as an autosomal dominant disorder. The prevalence of heterozygous PC deficiency is estimated to be 1 to 4% in venous thrombotic diseases. The homozygous PC deficiency is even rare, and has been reported in only about 10 families througout the world. It usually presents in newborn infants as purpura fulminans or severe thrombotic disease. We herein report two newborn brothers in a Chinese family, who manifested with purpura fulminans soon after birth and died at age of
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Oh, Hye-rim, Kaipeng Jing, Soyeon Shin, et al. "Abstract 1985: Omega-3 polyunsaturated fatty acids induce cell cytotoxicity through apoptosis and autophgy in brain cancer in vitro and in vivo." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1985.

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