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Dissertations / Theses on the topic 'Bactera/phage interactions'

Author: Grafiati
Published: 25 January 2025
Last updated: 31 July 2025

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1

Bou, habib Michèle. "Développement et analyse d'un modèle dynamique d'attaque de phages lors de l'acidification du lait pour la fabrication du fromage." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASB061.

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Avec l'augmentation de la demande pour les produits fromagers, l'optimisation des procédés de production est devenue essentielle. L'une des premières étapes de la fabrication du fromage est l'acidification du lait, qui influence fortement les propriétés organoleptiques, la texture et la sécurité du produit final. Elle consiste à convertir le lactose, sucre du lait, en acide lactique par des bactéries lactiques. Cependant, ces bactéries sont sensibles aux attaques de virus appelés bactériophages. Ces attaques peuvent entraîner la lyse bactérienne, retardant ou arrêtant l'acidification, ce qui e
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2

Bankier, Claire. "Coevolutionary interactions between bacteria and phage in natural environments." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/44556.

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Bacteria and their viruses (bacteriophage, phage) are the most abundant and diverse taxonomic groups, but ecological and evolutionary research on bacteria-phage interactions has largely focused on studies of simplified communities using a few model organisms. The goal of the thesis is to understand how bacteria and phage interact within natural environments, and how these interactions impact the patterns of phage infectivity and bacterial resistance. Here I investigate the effects of natural environments on the coevolutionary patterns of bacteria (Pseudomonas fluorescens) and phage (SBW25Φ2).
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3

Marcinkiewicz, Ashley. "Bacterial and phage interactions influencing Vibrio parahaemolyticus ecology." Thesis, University of New Hampshire, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10127507.

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<p> <i>Vibrio parahaemolyticus,</i> a human pathogenic bacterium, is a naturally occurring member of the microbiome of the Eastern oyster. As the nature of this symbiosis in unknown, the oyster presents the opportunity to investigate how microbial communities interact with a host as part of the ecology of an emergent pathogen of importance. To define how members of the oyster bacterial microbiome correlate with <i>V. parahaemolyticus,</i> I performed marker-based metagenetic sequencing analyses to identify and quantify the bacterial community in individual oysters after culturally-quantifying
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4

Gonzalez, Floricel. "Investigation of flagellotropic phage interactions with their motile host bacteria." Diss., Virginia Tech, 2021. http://hdl.handle.net/10919/103940.

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Bacteriophages cohabit with their bacterial hosts and shape microbial communities. To initiate infection, phages use bacterial components as receptors to recognize and attach to hosts. Flagellotropic phages utilize bacterial flagella as receptors. Studies focused on uncovering mechanistic details of flagellotropic phage infection are lacking. As the number of phage-based applications grows, it is important to understand these details to predict the potential outcomes of phage therapy. To this end, we studied two flagellotropic phages: Agrobacterium phage 7-7-1 and bacteriophage χ. Phage 7-7-1
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5

Räisänen, L. (Liisa). "Phage-host interactions in Lactobacillus delbrueckii: host recognition and transcription of early phage genes." Doctoral thesis, University of Oulu, 2007. http://urn.fi/urn:isbn:9789514284250.

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Abstract The scope of this study includes aspects of phage evolution and antagonistic/mutualistic coevolution between a phage and its host. As a basic study it may provide tools for developing phage resistant starters and offer regulatory elements and factors for biotechnological applications. The LL-H anti-receptor was characterized by isolation of spontaneous LL-H host range mutants and subsequent sequencing of candidate genes. All LL-H host range mutants carried a single point mutation at the 3' end of a minor tail protein encoding gene g71. The genomic location of g71 is congruent with th
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6

McLean, Hector Alexander. "Application of phage display to the study of toxin-receptor interactions." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301779.

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7

Flores, Garcia César O. "Phage--Bacteria Infection networks: from nestedness to modularity and back again." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53007.

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Bacteriophages (viruses that infect bacteria) are the most abundant biological life-forms on Earth. However, very little is known regarding the structure of phage-bacteria infections. In a recent study we showed that phage-bacteria infection assay datasets are statistically nested in small scale communities while modularity is not statistically present. We predicted that at large macroevolutionary scales, phage-bacteria infection assay datasets should be typified by a modular structure, even if there is nested structure at smaller scales. We evaluate and confirm this hypothesis using the large
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8

Mansos, Lourenço Marta. "Deciphering in vivo efficacy of virulent phages in the mammalian gut." Electronic Thesis or Diss., Sorbonne université, 2019. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2019SORUS260.pdf.

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L'intestin des mammifères est peuplé de nombreux et divers microbes comprenant des bactéries et leurs prédateurs viraux, des bactériophages (phages). Les interactions entre les phages et les bactéries intestinales sont encore mal comprises. Des expériences indépendantes ont montré que les phages virulents n’avaient aucun effet majeur sur l’abondance des bactéries intestinales ciblées, en dépit de leur amplification durable. Cela suggère que des facteurs encore inconnus de l'environnement intestinal modulent ces interactions. À l’aide d’une analyse transcriptomique comparative de la bactérie Es
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9

Hosseinidoust, Zeinab. "An investigation of bacteriophage-bacteria interactions: development of phage resistance and associated variations in virulence and biofilm formation." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114443.

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The rise of antibiotic resistance has rekindled interest in the development of alternative antimicrobial agents. Bacteriophages, bacteria's obligate parasites, have drawn a lot of interest from the scientific community and from the industry due to their many advantages. However, there are various challenges hindering the use of bacteriophages as antimicrobial agents. In this dissertation, a number of these challenges have been addressed. After a brief introduction on the advantages and drawbacks of using phage in chapter one, the inherent limitation of using immobilized phage for antimicrobial
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10

Feichtmayer, Judith [Verfasser], Christian [Akademischer Betreuer] Griebler, Wolfgang [Gutachter] Liebl, and Christian [Gutachter] Griebler. "Bacteria-phage interactions: Insights into quorum sensing-induced anti-phage defense, phage therapy and the pulmonary human virome composition / Judith Feichtmayer ; Gutachter: Wolfgang Liebl, Christian Griebler ; Betreuer: Christian Griebler." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/1193650429/34.

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11

Howard-Varona, Cristina. "Phage Fate: Infection Dynamics and Outcomes in a Marine Virus - Host System." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/556856.

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Viruses infecting bacteria (phages) are the most abundant and ubiquitous entities on Earth and likely critical to any ecosystem, as they influence nutrient cycling, mortality and evolution. Ultimately, their impact depends on whether phage—host interactions lead to intracellular phage coexistence (temperate phage) or cell death (lytic phage). Temperate phages in the lysogenic cycle replicate their genome (either integrated into the host chromosome or extrachromosomally), until induced to become lytic, when they create and release progeny via cell lysis. While knowledge on lytic versus lysogeni
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12

Katsamba, Panayiota. "Biophysics of helices : devices, bacteria and viruses." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/283006.

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A prevalent morphology in the microscopic world of artificial microswimmers, bacteria and viruses is that of a helix. The intriguingly different physics at play at the small scale level make it necessary for bacteria to employ swimming strategies different from our everyday experience, such as the rotation of a helical filament. Bio-inspired microswimmers that mimic bacterial locomotion achieve propulsion at the microscale level using magnetically actuated, rotating helical filaments. A promising application of these artificial microswimmers is in non-invasive medicine, for drug delivery to tu
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13

Bröker, Nina Kristin. "Die Erkennung komplexer Kohlenhydrate durch das Tailspike Protein aus dem Bakteriophagen HK620." Phd thesis, Universität Potsdam, 2012. http://opus.kobv.de/ubp/volltexte/2012/6036/.

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Kohlenhydrate stellen aufgrund der strukturellen Vielfalt und ihrer oft exponierten Lage auf Zelloberflächen wichtige Erkennungsstrukturen dar. Die Wechselwirkungen von Proteinen mit diesen Kohlenhydraten vermitteln einen spezifischen Informationsaustausch. Protein-Kohlenhydrat-Interaktionen und ihre Triebkräfte sind bislang nur teilweise verstanden, da nur wenig strukturelle Daten von Proteinen im Komplex mit vorwiegend kleinen Kohlenhydraten erhältlich sind. Mit der vorliegenden Promotionsarbeit soll ein Beitrag zum Verständnis von Protein-Kohlenhydrat-Wechselwirkungen durch Analysen struktu
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14

Angardi, Vahideh. "Bioprocess Development For Thermostable Glucose Isomerase Production." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613909/index.pdf.

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In this study, process development for glucose isomerase (GI) was aimed. In this context, firstly, thermostable xyl genes, PCR amplified from Thermus thermophilus and Pyrococcus furiosus cells, were recombined to the E.coli BL21 (DE3) and P.pastoris strains, respectively. But significant increase in the term of GI activity compared with wild type cells only detected in recombinant E.coli strain so this strain was selected for further experiments. Then, the effect of different natural and artificial inducers on the production of rGI under control of LacUV5 promoter was investigated in laborator
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15

(9243635), Ikenna O. Okekeogbu. "GLOBAL PROTEOME INVESTIGATION OF MYCOBACTERIOPHAGE OCHI17-MYCOBACTERIUM SMEGMATIS INTERACTIONS." Thesis, 2020.

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<p>Bacteriophages (phages) have broad applications in diverse areas including phage therapy, agriculture, food safety, and environmental protection. In order to fully realize the potential for phage applications, it is critical to understand phage-bacteria interactions and characterize bacterial responses/targets to phage infection. Previous studies have largely focused on other classes of phages other than mycobacteriophages. This research provides the first global proteome investigation of the dynamic relationship between a mycobacteriophage and a mycobacterial host. Mycobacteriophages are v
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16

Duarte, Ana Catarina Leal. "Interaction of phages with biofilms of single and mixed multidrug resistant species involved in pneumonia infections." Master's thesis, 2018. http://hdl.handle.net/1822/59144.

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Dissertação de mestrado em Biotechnology<br>Pseudomonas aeruginosa and Acinetobacter baumannii are two Gram-negative pathogens frequently involved in hospital infections, including pneumonia or cystic fibrosis. Most infections caused by these bacteria are difficult to treat because of their low susceptibility to antibiotics, which is often associated with their ability to adhere to surfaces and form biofilms. Therefore, the World Health Organization has classified these microorganisms as top priority bacteria that urgently require the development of novel therapeutic approaches. Bacteriophages
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