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Journal articles on the topic 'Bacteria infection'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Tae-Bong, Kang, Hisham Yasmin, Lee Youngmin, Jhun Hyunjhung, Kim Joohee, and Kim Soohyun. "Diabetes and bacterial infection." International Journal of Clinical Endocrinology and Metabolism 8, no. 1 (2022): 001–8. http://dx.doi.org/10.17352/ijcem.000054.

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People with diabetes are at increased risk of infection and are worried about biological agents such as bacteria. Particularly, foot infections, urinary tract infections, pneumonia, and skin diseases are due to bacterial infections that make diabetic patients suffer from clinical difficulties. Although antibiotics, one of the bacterial therapies, have been used, the emergence of multidrug-resistant bacteria is now in demand for alternative therapies. Although, many studies reported that antibiotic-resistant for bacterial infections and their rate have increased significantly in the diabetic pa

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Preveden, Tomislav. "Bacterial infections in patients with liver cirrhosis." Medical review 68, no. 5-6 (2015): 187–91. http://dx.doi.org/10.2298/mpns1506187p.

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Introduction. Liver cirrhosis is characterized by a reduced defensive reaction to bacterial infections and patients with cirrhosis are at increased risk of developing infections, sepsis and death. The most common bacterial infections in these patients are spontaneous bacterial peritonitis, urinary tract infection, pneumonia, skin and soft tissue infection and bacteremia. The most common causes are Gram negative bacteria. The aim of this study was to determine the prevalence, localization and etiology of bacterial infections in hospitalized patients with liver cirrhosis. Material and Methods. T

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Zegadło, Katarzyna, Monika Gieroń, Paulina Żarnowiec, et al. "Bacterial Motility and Its Role in Skin and Wound Infections." International Journal of Molecular Sciences 24, no. 2 (2023): 1707. http://dx.doi.org/10.3390/ijms24021707.

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Skin and wound infections are serious medical problems, and the diversity of bacteria makes such infections difficult to treat. Bacteria possess many virulence factors, among which motility plays a key role in skin infections. This feature allows for movement over the skin surface and relocation into the wound. The aim of this paper is to review the type of bacterial movement and to indicate the underlying mechanisms than can serve as a target for developing or modifying antibacterial therapies applied in wound infection treatment. Five types of bacterial movement are distinguished: appendage-

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Ali, Zainab Haider, Wurood Hamzah Muttaleb, and Lubna Abdulazeem. "Anti-Bacterial Action of Silver Nanoparticles Against MDR Bacteria Isolated from Hospital." International Journal of Medical Science and Dental Health 10, no. 10 (2024): 93–99. http://dx.doi.org/10.55640/ijmsdh-10-10-11.

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Hospital-associated infections (HAIs) are considered to be a major source of infections in patients, especially in patients with permanently impaired immunity. There is alarming increase of multi drug resistant (MDR) bacteria and Antibacterial medication resistance has been deemed a serious hazard to public health by the World Health Organisation (WHO). The study aimed to isolate and identify main bacteria caused nosocomial infection, and trying to treatments by using nanoparticles. By measuring the antibacterial activity of the synthesised AgNPs using the agar disc diffusion technique, AgNPs

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Duhaniuc, Alexandru, Diana Păduraru, Eduard-Vasile Nastase, et al. "Multidrug-Resistant Bacteria in Immunocompromised Patients." Pharmaceuticals 17, no. 9 (2024): 1151. http://dx.doi.org/10.3390/ph17091151.

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The increasing incidence of antibiotic resistance in bacteria is a major problem in terms of therapeutic options, especially in immunocompromised patients, such as patients from intensive care units (ICUs), HIV-positive patients, patients with malignancies or transplant patients. Commensal bacteria, especially anaerobes, serve to maintain microbial stability by preventing overpopulation with pathogenic bacteria. In immunocompromised patients, microbiota imbalance caused by antibiotic therapy and decreased host immunity favors intestinal overpopulation with pathogenic species, leading to increa

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Shruti, Sinha, and Srivastava* Soumya. "Bacteriophage and Phage-Therapy: An Alternative to Antibiotics." eLifePress 1, no. 1 (2020): 21–27. https://doi.org/10.5281/zenodo.4307923.

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Bacteriophages are known for a century but their use in therapy to cure bacterial infection is still unknown. The working on bacteriophage investigation started about a century ago with their discovery by the English microbiologist Twort in 1915. The continuous growth of resistance in bacteria for various diseases and infections has caused renewing in bacteriophage therapy against bacterial infections. Lytic bacteriophages are those bacteriophages that can kill bacteria that are resistant to antibiotics by the end of their lytic cycle. Bacteriophages use proteins for the lysis of bacteria, ter

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Yoon, Taekeun, and Sang Wha Kim. "Negative-Pressure Wound Therapy in a Patient with Osteomyelitis Caused by Multidrug-Resistant Bacterial Infection: A Case Report." Journal of Wound Management and Research 17, no. 3 (2021): 193–97. http://dx.doi.org/10.22467/jwmr.2021.01746.

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Uncontrolled infection, especially with multidrug-resistant bacteria, may significantly inhibit wound healing. Although negative-pressure wound therapy can help prevent infection, it is contraindicated in patients with untreated infections, including osteomyelitis. Here, we report successful wound healing by negative-pressure wound therapy in a patient with refractory osteomyelitis due to multiple multidrug-resistant bacterial infections. Soft tissue infection and osteomyelitis progressed deeply through subcutaneous tunneling; hence, bacteria were not excreted from the affected area. Negative-

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Nagasawa, Yasuyuki, Taro Misaki, Seigo Ito, et al. "Title IgA Nephropathy and Oral Bacterial Species Related to Dental Caries and Periodontitis." International Journal of Molecular Sciences 23, no. 2 (2022): 725. http://dx.doi.org/10.3390/ijms23020725.

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A relationship between IgA nephropathy (IgAN) and bacterial infection has been suspected. As IgAN is a chronic disease, bacteria that could cause chronic infection in oral areas might be pathogenetic bacteria candidates. Oral bacterial species related to dental caries and periodontitis should be candidates because these bacteria are well known to be pathogenic in chronic dental disease. Recently, several reports have indicated that collagen-binding protein (cnm)-(+) Streptococcs mutans is relate to the incidence of IgAN and the progression of IgAN. Among periodontal bacteria, Treponema dentico

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Pigozzo, Alexandre Bittencourt, Gilson Costa Macedo, Rodrigo Weber dos Santos, and Marcelo Lobosco. "Computational Modeling of Microabscess Formation." Computational and Mathematical Methods in Medicine 2012 (2012): 1–16. http://dx.doi.org/10.1155/2012/736394.

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Bacterial infections can be of two types: acute or chronic. The chronic bacterial infections are characterized by being a large bacterial infection and/or an infection where the bacteria grows rapidly. In these cases, the immune response is not capable of completely eliminating the infection which may lead to the formation of a pattern known as microabscess (or abscess). The microabscess is characterized by an area comprising fluids, bacteria, immune cells (mainly neutrophils), and many types of dead cells. This distinct pattern of formation can only be numerically reproduced and studied by mo

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Ichsanto Permadi, Adeh Mahardika, and Misriyani. "Case Report: A 52-year-old female with Bacterial Infection and Drug Allergy." World Journal of Advanced Research and Reviews 25, no. 30 (2025): 238–51. https://doi.org/10.30574/wjarr.2025.25.3.0679.

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This bacterial infection has a major impact on public health. There are many bacteria that are able to adapt to survive in water, soil, food, and various other places. The development of bacterial infection to cause disease is influenced by several factors including the infectivity of the organism, the pathogenicity of infectious organisms, the ability of pathogenic bacteria to avoid the body's immunity, virulence factors of pathogenic bacteria, and the role of human immunity cells themselves. In the treatment of patients with bacterial infections there are some real challenges in the use of d

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Thomas, Christian A., Yongmei Li, Tatsuhiko Kodama, Hiroshi Suzuki, Samuel C. Silverstein, and Joseph El Khoury. "Protection from Lethal Gram-Positive Infection by Macrophage Scavenger Receptor–Dependent Phagocytosis." Journal of Experimental Medicine 191, no. 1 (2000): 147–56. http://dx.doi.org/10.1084/jem.191.1.147.

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Infections with gram-positive bacteria are a major cause of morbidity and mortality in humans. Opsonin-dependent phagocytosis plays a major role in protection against and recovery from gram-positive infections. Inborn and acquired defects in opsonin generation and/or recognition by phagocytes are associated with an increased susceptibility to bacterial infections. In contrast, the physiological significance of opsonin-independent phagocytosis is unknown. Type I and II class A scavenger receptors (SR-AI/II) recognize a variety of polyanions including bacterial cell wall products such as lipopol

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Toyyibah, Ilma Dzurriyyatan, Musofa Rusli, and Juniastuti Juniastuti. "BACTERIAL PATTERN AMONG SEPSIS PATIENTS IN INTERNAL MEDICINE INPATIENT WARD DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN 2017-2019." Majalah Biomorfologi 32, no. 2 (2022): 52–58. http://dx.doi.org/10.20473/mbiom.v32i1.2022.52-58.

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Highlights:1. Bacteria remain a major cause of bacterial sepsis.2. The most common causal agent in bacterial septicaemia was the gram-positive bacterium. Abstract: Background: Bacteria remain the primary cause of bacterial sepsis. Gram-negative bacteria are the most commonly isolated from sepsis patients. However, gram-positive bacterial infections have also increased recently. Objective: To identify the pattern of bacterial infection in sepsis patients in Internal Medicine inpatient ward Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Material and Method: This retrospective study

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Manandhar, Ruchee, Bijendra Raj Raghubanshi, Moni Mahato, Sweekrity Neupane, and Rajni Lama. "Bacteriological Profile and Antimicrobial Susceptibility Patterns of Urine Culture Isolates from Patients in a Tertiary Care Centre in Lalitpur." Birat Journal of Health Sciences 5, no. 1 (2020): 881–85. http://dx.doi.org/10.3126/bjhs.v5i1.29602.

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Introduction: Urinary tract infection (UTI) is a microbial infection of the urinary system involving the urinary tract anywhere from kidney to urethra. It is one of the most common bacterial infections affecting men and women in developing countries with a high rate of morbidity and financial cost. Objectives: The objective of our study is to study the prevalence of UTI in patients attending KIST Medical College & Teaching Hospital (KISTMCTH), and determine the antimicrobial susceptibility pattern of bacteria thus isolated. Methodology: A total of 3742 urine samples from patien

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Wendling, Carolin C., Henry Goehlich, and Olivia Roth. "The structure of temperate phage–bacteria infection networks changes with the phylogenetic distance of the host bacteria." Biology Letters 14, no. 11 (2018): 20180320. http://dx.doi.org/10.1098/rsbl.2018.0320.

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With their ability to integrate into the bacterial chromosome and thereby transfer virulence or drug-resistance genes across bacterial species, temperate phage play a key role in bacterial evolution. Thus, it is paramount to understand who infects whom to be able to predict the movement of DNA across the prokaryotic world and ultimately the emergence of novel (drug-resistant) pathogens. We empirically investigated lytic infection patterns among Vibrio spp. from distinct phylogenetic clades and their derived temperate phage. We found that across distantly related clades, infections occur prefer

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Santos-Matos, Gonçalo, Nicky Wybouw, Nelson E. Martins, et al. "Tetranychus urticae mites do not mount an induced immune response against bacteria." Proceedings of the Royal Society B: Biological Sciences 284, no. 1856 (2017): 20170401. http://dx.doi.org/10.1098/rspb.2017.0401.

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The genome of the spider mite Tetranychus urticae , a herbivore, is missing important elements of the canonical Drosophila immune pathways necessary to fight bacterial infections. However, it is not known whether spider mites can mount an immune response and survive bacterial infection. In other chelicerates, bacterial infection elicits a response mediated by immune effectors leading to the survival of infected organisms. In T. urticae , infection by either Escherichia coli or Bacillus megaterium did not elicit a response as assessed through genome-wide transcriptomic analysis. In line with th

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Schubert, Pawel T., Deidre Mason, Roosacelis Martines, Marlene Deleon-Carnes, Sherif R. Zaki, and Drucilla J. Roberts. "Spectrum of Changes Seen With Placental Intravascular Organisms." Pediatric and Developmental Pathology 22, no. 3 (2018): 229–35. http://dx.doi.org/10.1177/1093526618801616.

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Fetal bacterial infections are a common cause of fetal/neonatal morbidity and mortality. The pathologic correlates of congenital bacterial infection include acute chorioamnionitis, acute villitis, and acute intervillositis. The strength of the association of congenital bacterial infection differs among these pathologies. Acute chorioamnionitis results usually from an ascending infection, and damage to the fetus is thought to be cytokine driven rather than damage secondary to bacteremia. Acute villitis is strongly associated with fetal sepsis due to congenital infections. A much less common var

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El Baroudy, Nevine R., Amira S. El Rifay, Tamer A. Abdel Hamid, Dina M. Hassan, May S. Soliman, and Lobna Sherif. "Respiratory Viruses and Atypical Bacteria Co-Infection in Children with Acute Respiratory Infection." Open Access Macedonian Journal of Medical Sciences 6, no. 9 (2018): 1588–93. http://dx.doi.org/10.3889/oamjms.2018.332.

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BACKGROUND: Acute respiratory infections (ARI) are one of the prevalent pediatric diseases. Coinfections of respiratory viruses and atypical bacterial respiratory pathogens are common.AIM: This study aimed to determine the prevalence of co-infection between respiratory pathogens including viruses, bacteria and atypical bacteria in a sample of Egyptian children presenting with symptoms of acute respiratory tract infection.METHODS: This one-year prospective cohort study conducted in Abo El Rish Pediatric Hospital, Cairo University over one year included children presenting with symptoms of acute

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Chokshi, Shivan N., George Golovko, Juquan Song, et al. "115 Analyzing Temporal Trends and Outcomes Associated with High Prevalence Bacterial Infections in Burn Patients." Journal of Burn Care & Research 43, Supplement_1 (2022): S74—S75. http://dx.doi.org/10.1093/jbcr/irac012.117.

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Abstract Introduction Bacterial infections are a leading cause of complications in burn patients. However, ambiguity remains around the most common infectious etiologies and their resulting complications. Our study identifies which bacterial infections will lead to specific complications and tracks infection rates of these bacteria over time. Methods Burn patients diagnosed with a bacterial infection within 6 months of burn were identified in the TriNetX database using ICD-10 codes; those with bacterial infections prior to injury were excluded. Occurrence of the following outcomes within 12 mo

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Sabra, Sherifa. "Elimination Virulent-pathogenic-biofilm Bacteria Using Highland-wild Salvia officinalis Preserve Bacterial-infection-control." Biotechnology and Bioprocessing 2, no. 2 (2021): 01–04. http://dx.doi.org/10.31579/2766-2314/021.

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This work for this title "Elimination Virulent-pathogenic-biofilm (VPB) Bacteria Using Highland-wild (HLW) Salvia officinalis (S. officinalis) Preserve Bacterial-infection-control (BIC)"; the aim was to prove the importance of HLW S. officinalis extracts have therapeutic herbal importance. Through its effected on the isolated VPB bacteria caused infection diseases that may preserve BIC for individuals, which proved the effectiveness of the HLW S. officinalis daily use or therapeutic use. S. officinalis specimens were collected during the flowering period from HLW, Taif, KSA. Essential oils (EO

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Paukner, Susanne, Gregory J. Moran, Christian Sandrock, et al. "A plain language summary of how lefamulin alone can be used to treat pneumonia caught outside of the hospital due to common bacterial causes, including drug-resistant bacteria." Future Microbiology 17, no. 6 (2022): 397–410. http://dx.doi.org/10.2217/fmb-2021-0276.

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What is this summary about? Bacterial pneumonia is an infection of the lung caused by bacteria that is potentially deadly, costly, and affects millions of people worldwide every year. Treatment is becoming more challenging—many current treatments no longer work well because some strains of bacteria that cause pneumonia have become resistant to current antibiotics. Many of the antibiotics that do still work have undesirable side effects. Therefore, new antibiotics that work differently are needed to treat bacterial pneumonia. Lefamulin (brand name, Xenleta®) is an antibiotic that was approved t

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Abedon, Stephen T. "Phage-Antibiotic Combination Treatments: Antagonistic Impacts of Antibiotics on the Pharmacodynamics of Phage Therapy?" Antibiotics 8, no. 4 (2019): 182. http://dx.doi.org/10.3390/antibiotics8040182.

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Bacteria can evolve resistance to antibiotics. Even without changing genetically, bacteria also can display tolerance to antibiotic treatments. Many antibiotics are also broadly acting, as can result in excessive modifications of body microbiomes. Particularly for antibiotics of last resort or in treating extremely ill patients, antibiotics furthermore can display excessive toxicities. Antibiotics nevertheless remain the standard of care for bacterial infections, and rightly so given their long track records of both antibacterial efficacy and infrequency of severe side effects. Antibiotics do

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Liu, Shengbi, Chao Yu, Qin Tu, et al. "Bacterial co-infection in COVID-19: a call to stay vigilant." PeerJ 12 (September 19, 2024): e18041. http://dx.doi.org/10.7717/peerj.18041.

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Co-infection with diverse bacteria is commonly seen in patients infected with the novel coronavirus, SARS-CoV-2. This type of co-infection significantly impacts the occurrence and development of novel coronavirus infection. Bacterial co-pathogens are typically identified in the respiratory system and blood culture, which complicates the diagnosis, treatment, and prognosis of COVID-19, and even exacerbates the severity of disease symptoms and increases mortality rates. However, the status and impact of bacterial co-infections during the COVID-19 pandemic have not been properly studied. Recently

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Klimpel, G. R., R. Shaban, and D. W. Niesel. "Bacteria-infected fibroblasts have enhanced susceptibility to the cytotoxic action of tumor necrosis factor." Journal of Immunology 145, no. 2 (1990): 711–17. http://dx.doi.org/10.4049/jimmunol.145.2.711.

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Abstract The susceptibility of bacteria-infected fibroblasts to the cytotoxic action of tumor necrosis factor was investigated. L cells infected with Shigella flexneri, Salmonella typhimurium, or Listeria monocytogenes, had an enhanced susceptibility to the cytotoxic activity of TNF-alpha. This enhanced susceptibility was dependent upon the challenge dose of bacteria, the concentration of TNF, and upon the exposure time of bacteria-infected cells to TNF. L cells infected with S. flexneri were susceptible to the cytotoxic action of TNF at 2 to 6 h after bacterial infection. In contrast, L cells

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Hill, Harry R. "Granulocyte Transfusions in Neonates." Pediatrics In Review 12, no. 10 (1991): 298–302. http://dx.doi.org/10.1542/pir.12.10.298.

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Human neonates, especially those born prematurely, are prone to developing overwhelming infections in response to bacterial pathogens. It is estimated that 1 to 8 per 1000 live births are complicated by such infections. Moreover, almost 30% of neonatal mortality and morbidity can be attributed to neonatal infection. Thus, in spite of all of the support measures offered in neonatal intensive care units and the use of new, potent antimicrobial agents, we continue to lose far too many infants to overwhelming infections. It is likely that we have come as far as we can with these accepted regimens

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Keith, James W., and Eric G. Pamer. "Enlisting commensal microbes to resist antibiotic-resistant pathogens." Journal of Experimental Medicine 216, no. 1 (2018): 10–19. http://dx.doi.org/10.1084/jem.20180399.

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The emergence of antibiotic-resistant bacterial pathogens is an all-too-common consequence of antibiotic use. Although antibiotic resistance among virulent bacterial pathogens is a growing concern, the highest levels of antibiotic resistance occur among less pathogenic but more common bacteria that are prevalent in healthcare settings. Patient-to-patient transmission of these antibiotic-resistant bacteria is a perpetual concern in hospitals. Many of these resistant microbes, such as vancomycin-resistant Enterococcus faecium and carbapenem-resistant Klebsiella pneumoniae, emerge from the intest

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Dow, Steven W., Robert L. Jones, and William S. Adney. "Anaerobic bacterial infections and response to treatment in dogs and cats: 36 cases (1983–1985)." Journal of the American Veterinary Medical Association 189, no. 8 (1986): 930–34. https://doi.org/10.2460/javma.1986.189.08.930.

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SUMMARY Anaerobic bacteria have been increasingly implicated as important pathogens in animals. To determine the prevalence of anaerobic bacterial infection, the results of anaerobic bacteriologic culture of 599 specimens obtained from dogs and cats hospitalized at the Colorado State University Veterinary Teaching Hospital were reviewed. Obligate anaerobic bacteria were isolated from 35% of properly submitted specimens; Bacteroides spp and Fusobacterium spp were the organisms most commonly isolated. Infections most often containing anaerobes were abscesses, pleuropulmonary infections, and abdo

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Aljanaby, Ahmed Abduljabbar Jaloob, and Israa Abduljabbar Jaloob Aljanaby. "Prevalence of aerobic pathogenic bacteria isolated from patients with burn infection and their antimicrobial susceptibility patterns in Al-Najaf City, Iraq- a three-year cross-sectional study." F1000Research 7 (July 30, 2018): 1157. http://dx.doi.org/10.12688/f1000research.15088.1.

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Background: Burn infections are one of the most common serious illnesses caused by pathogens, mainly by both gram-negative and gram-positive bacteria. The aim of this study was to detect of the prevalence of multi-drug resistant and extended-spectrum β-lactamase-producing (ESBL) bacteria isolated from inpatients with burn infection and the antimicrobials sensitivity patterns of all bacterial isolates during three years. Methods: This cross-sectional study was performed in Al-Najaf Central Hospital in Al-Najaf City, Iraq from January 2015 to December 2017. A total of 295 burns swabs were collec

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Myckatyn, Terence M., Jesus M. Duran Ramirez, Jennifer N. Walker, and Blake M. Hanson. "Management of Biofilm with Breast Implant Surgery." Plastic & Reconstructive Surgery 152, no. 5 (2023): 919e—942e. http://dx.doi.org/10.1097/prs.0000000000010791.

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Learning Objectives: After studying this article, the participant should be able to: 1. Understand how bacteria negatively impact aesthetic and reconstructive breast implants. 2. Understand how bacteria infect breast implants. 3. Understand the evidence associated with common implant infection-prevention strategies, and their limitations. 4. Understand why implementation of bacteria-mitigation strategies such as antibiotic administration or “no-touch” techniques may not indefinitely prevent breast implant infection. Summary: Bacterial infection of aesthetic and reconstructive breast implants i

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Hashim Morad, Dalia Sudad, Sarah Hashim Oubid, Nour Abdulehsan Dhannoon, and Ali M. Saadi. "Aetiology of urinary tract infection: A review." International Journal of Medical and All Body Health Research 5, no. 3 (2024): 01–07. http://dx.doi.org/10.54660/ijmbhr.2024.5.3.01-07.

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Urinary tract infection is one of the common conditions all over the world, in this review the most important infections of urinary tract infection, as many people suffer from this infection continuously. One of the most important causes of infection are fungal, viral and bacterial pathogens, including Eschericia coli bacteria, coliforms and enterocci, common bacterial causes of UTIs, which are present in numbers.

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Kodet, Ondřej. "Bacterial skin infection II. - infection induced by gram-negative bacteria." Dermatologie pro praxi 18, no. 1 (2024): 5–9. http://dx.doi.org/10.36290/der.2024.001.

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Vallet-Regí, María, Blanca González, and Isabel Izquierdo-Barba. "Nanomaterials as Promising Alternative in the Infection Treatment." International Journal of Molecular Sciences 20, no. 15 (2019): 3806. http://dx.doi.org/10.3390/ijms20153806.

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Both the prevalence of antibiotic resistance and the increased biofilm-associated infections are boosting the demand for new advanced and more effective treatment for such infections. In this sense, nanotechnology offers a ground-breaking platform for addressing this challenge. This review shows the current progress in the field of antimicrobial inorganic-based nanomaterials and their activity against bacteria and bacterial biofilm. Herein, nanomaterials preventing the bacteria adhesion and nanomaterials treating the infection once formed are presented through a classification based on their f

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Burkaltseva, Maria V., A. V. Lazareva, E. A. Pleteneva, et al. "Imaging of the bacterial interactions in lung co-infection in cystic fibrosis patients." Clinical Microbiology and Antimicrobial Chemotherapy 22, no. 2 (2020): 155–60. http://dx.doi.org/10.36488/cmac.2020.2.155-160.

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Objective. To identify bacterial interactions at the site of infection in cystic fibrosis patients and to assess their possible effects on the course of infection. Materials and Methods. The following strains were used in this study: Alcaligenes faecalis LGBP strain, isolated from the environment; clinical isolates of Pseudomonas aeruginosa; Achromobacter xylosoxidans, Acinetobacter baumannii, Alcaligenes faecalis, and Bacillus subtilis strains; the standard laboratory P. aeruginosa PAO1 strain and its lysogens by temperate bacteriophages of various species, and its phageresistant mutants. Ima

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Jakobsen, Tim Holm, Julius Bier Kirkegaard, Mads Lichtenberg, et al. "Detection limitations of bacteria in tissue samples." Bone & Joint Research 14, no. 6 (2025): 560–67. https://doi.org/10.1302/2046-3758.146.bjr-2024-0410.r1.

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AimsSuccessful identification of bacteria in tissue samples requires careful consideration of multiple factors, including sample type and quality, the type of bacteria being detected, and the sensitivity and specificity of the detection method. Here, we address the issues of detecting a small number of bacteria, often found in biofilms and heterogeneously distributed in a large volume (the surgical site with suspected infection). Specifically, the study seeks to address the difficulties in detecting small numbers of bacteria, and to evaluate the impact of bacterial aggregation on the probabili

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Stanković, Stefan, and Irena Đunić. "Bacterial infections in patients in allogenic stem cell transplantation programs." Srpski medicinski casopis Lekarske komore 3, no. 1 (2022): 45–54. http://dx.doi.org/10.5937/smclk3-35312.

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Introduction: Bacterial infections are common in patients enrolled in allogenic hematopoietic stem cell transplantation. Infections are the most common cause of illness and mortality in transplanted patients. The most common pathogens are Staphylococcus and Enterobacteriaceae, causing 25% of bacterial infections, each, followed by Enterococcus andP. aeruginosa. Aim: The aim of the paper is calculating the frequency of bacterial infections in patients enrolled in allogenic hematopoietic stem cell transplantation, at the Clinic for Hematology of the University Clinical Center of Serbia, as well

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Secor, Patrick R., Lia A. Michaels, Anina Ratjen, Laura K. Jennings, and Pradeep K. Singh. "Entropically driven aggregation of bacteria by host polymers promotes antibiotic tolerance inPseudomonas aeruginosa." Proceedings of the National Academy of Sciences 115, no. 42 (2018): 10780–85. http://dx.doi.org/10.1073/pnas.1806005115.

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Bacteria causing chronic infections are generally observed living in cell aggregates suspended in polymer-rich host secretions, and bacterial phenotypes induced by aggregated growth may be key factors in chronic infection pathogenesis. Bacterial aggregation is commonly thought of as a consequence of biofilm formation; however the mechanisms producing aggregation in vivo remain unclear. Here we show that polymers that are abundant at chronic infection sites cause bacteria to aggregate by the depletion aggregation mechanism, which does not require biofilm formation functions. Depletion aggregati

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Yang, Yang, Qingfang Zhang, Haitao Hu, Wenyun Zhang, and Taohong Lu. "Bloodstream infection caused by Bacteroides caccae in a patient with renal hypertension: a case report." Journal of International Medical Research 49, no. 10 (2021): 030006052110472. http://dx.doi.org/10.1177/03000605211047277.

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Bacteroides caccae is an anaerobic bacterium with a reportedly high isolation rate; however, it rarely causes bloodstream infections. Patients with hypertension are at increased risk of developing anaerobic bacterial infection. In this study, we report a case of bacteremia caused by B. caccae in a patient with renal hypertension and gastrointestinal hemorrhage. This study describes the clinical manifestations of bloodstream infection involving B. caccae to provide guidance for laboratory technicians and clinicians. A 42-year-old Chinese man was admitted for gastrointestinal hemorrhage and subs

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Wieczorkiewicz, Klara, Anna Jarząbek, Estera Bakinowska, Kajetan Kiełbowski, and Andrzej Pawlik. "Microbial Dynamics in Endodontic Pathology—From Bacterial Infection to Therapeutic Interventions—A Narrative Review." Pathogens 14, no. 1 (2024): 12. https://doi.org/10.3390/pathogens14010012.

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Endodontic infection is a penetration of microorganisms into the dental pulp. Bacteria are the most common entities that induce an infection. This state is associated with significant pain and discomfort. Therapeutic intervention involves removal of infected pulp from the tooth and roots, which eliminates viable tissue, thus creating a tooth less resistant to mechanical pressure. Studies suggest that there are several types of bacteria most commonly associated with endodontic infections. Furthermore, it is considered that different types of pathogens could play a major role in primary and seco

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Zou, Pengfei, Wen-Ting Chen, Tongyi Sun, Yuanyuan Gao, Li-Li Li, and Hao Wang. "Recent advances: peptides and self-assembled peptide-nanosystems for antimicrobial therapy and diagnosis." Biomaterials Science 8, no. 18 (2020): 4975–96. http://dx.doi.org/10.1039/d0bm00789g.

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Bacterial infections, especially the refractory treatment of drug-resistant bacteria, are one of the greatest threats to human health. Self-assembling peptide-based strategies can specifically detect the bacteria at the site of infection in the body and kill it.

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Pallmer, K., S. Timeus, and R. Laoun. "P500 The use of budesonide results in lower risk for infections compared to systemic glucocorticoids." Journal of Crohn's and Colitis 16, Supplement_1 (2022): i462—i463. http://dx.doi.org/10.1093/ecco-jcc/jjab232.627.

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Abstract Background We analysed the occurrence of infections with individuals treated with either budenoside (locally acting) or systemically available glucocorticoids (GC); prednisolone, prednisone and methylprednisolone. The risk of infection was divided according to the origin; viruses, bacteria, fungi and parasites and we assessed which virus and bacterium caused the most side-effects between locally and systemically acting GC. Methods In this analysis, infection reported outcomes with GC drugs reported to FAERS (USA) were extracted and compared to approximately 25’000 drugs in the databas

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Abebe, Tigist, Zelalem Teklemariam, Tadesse Shume, Surafel Mekuria, Kedir Urgesa, and Fitsum Weldegebreal. "Bacterial Profile of External Ocular Infections, Its Associated Factors, and Antimicrobial Susceptibility Pattern among Patients Attending Karamara Hospital, Jigjiga, Eastern Ethiopia." International Journal of Microbiology 2023 (March 10, 2023): 1–9. http://dx.doi.org/10.1155/2023/8961755.

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Background. External ocular infection is a global public health problem. Frequently, bacteria cause an ocular infection that ranges from morbidity to loss of vision. The increasing bacterial resistance in ocular infections leads to the risk of treatment failure with possibly serious consequences. Objective. The study aimed to assess the bacterial profile of external ocular infections, their associated factors, and antimicrobial susceptibility pattern among patients admitted to Karamara hospital, Jigjiga, Eastern Ethiopia. Method. Institutional-basedcross-sectional study was conducted on 288 co

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Lovewell, Rustin R., Yash R. Patankar, and Brent Berwin. "Mechanisms of phagocytosis and host clearance ofPseudomonas aeruginosa." American Journal of Physiology-Lung Cellular and Molecular Physiology 306, no. 7 (2014): L591—L603. http://dx.doi.org/10.1152/ajplung.00335.2013.

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Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a high incidence of acute and chronic pulmonary infection. These infections are particularly prevalent in patients with chronic obstructive pulmonary disease and cystic fibrosis: much of the morbidity and pathophysiology associated with these diseases is due to a hypersusceptibility to bacterial infection. Innate immunity, primarily through inflammatory cytokine production, cellular recruitment, and phagocytic clearance by neutrophils and macrophages, is the key to endogenous control of P. aeruginosa infection. In th

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Khaliq, Tayyaba, and Muhammad Imran Qadir. "Phage Therapy as an alternative to Antibiotic Therapy against Urinary Tract Infections to Combat Antibiotic Resistance." JOURNAL OF MICROBIOLOGY AND MOLECULAR GENETICS 2, no. 2 (2021): 9–21. http://dx.doi.org/10.52700/jmmg.v2i2.30.

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Urinary tract infection is the global health problem being 2nd most common bacterial infection. The abuse of antibiotics without bacterial characterization during its treatment results in emergence of highly antibiotic-resistant bacteria. Some biofilm forming bacterial strains are hard to treat using antibiotics. So, an alternative therapy is urgently needed. Phage therapy offers promising results for treatment of these infections in which virulent or lytic phages are used to lyse infection-causing bacterial cells. This review emphasizes several ways in which phage therapy can be carried out a

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Kamolvit, Witchuda, Vera Nilsén, Silvia Zambrana, et al. "Lupinus mutabilis Edible Beans Protect against Bacterial Infection in Uroepithelial Cells." Evidence-Based Complementary and Alternative Medicine 2018 (December 16, 2018): 1–8. http://dx.doi.org/10.1155/2018/1098015.

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Lupinus mutabilis is a South American herb with edible beans, known to reduce serum glucose levels in diabetic patients. Furthermore, L. mutabilis contains phytochemicals known to decrease bacterial load. Based on the increased urinary tract infections experienced among patients with diabetes, we investigated the effect of L. mutabilis on bladder epithelial cells in the protection of E. coli infection during normal and high glucose concentrations. We did not observe any direct antibacterial effect by L. mutabilis extract. Instead we observed an influence on the host cells, with indirect impact

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Lan, Nguyen, Dau Lieu, Tran Anh, Le Thuong, Tran Tuong, and Mai Bang. "Characteristics and Related Factors of Bacterial Infection Among Patients With Cirrhosis." Materia Socio Medica 36, no. 1 (2024): 90. http://dx.doi.org/10.5455/msm.2024.36.90-96.

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Background: Infection causes cirrhosis to decompensate, affecting liver function and resulting in several complications, including esophageal variceal hemorrhage, hepatic encephalopathy, and hepatorenal syndrome. Objective: This study aimed to identify the prevalence, essential features, and related factors of bacterial infection among patients with cirrhosis in Vietnam. Methods: This retrospective study included 317 patients diagnosed with cirrhosis, who were divided into two groups: group 1 including 125 patients with bacterial infection and group 2 including 192 patients without bacterial i

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Partida-Sanchez, Santiago, Hanna Cortado, Dennis Horvath, Rollin Li, Emilio Flaño, and Sheryl Justice. "Nonclassical monocyte-derived macrophages are essential for preventing pyelonephritis upon urinary tract infection in mice (P4229)." Journal of Immunology 190, no. 1_Supplement (2013): 130.14. http://dx.doi.org/10.4049/jimmunol.190.supp.130.14.

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Abstract Phagocytes protect the urinary tract from bacterial infections (UTI). Neutrophils are required early upon infection for clearing off bacteria, however much less is known regarding the function of monocyte-derived macrophages during UTI. Two main subsets of blood monocytes can be distinguished by differential expression of the chemokine receptors CCR2 and CX3CR1. To determine the functional role of monocyte-derived phagocytes, we used CX3CR1 and CCR2 deficient mice and monitored the trafficking of monocyte-derived macrophages during the course of uropathogenic Escherichia coli (UPEC) i

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Gage, Daniel J. "Analysis of Infection Thread Development Using Gfp- and DsRed-Expressing Sinorhizobium meliloti." Journal of Bacteriology 184, no. 24 (2002): 7042–46. http://dx.doi.org/10.1128/jb.184.24.7042-7046.2002.

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ABSTRACT Sinorhizobium meliloti growth inside infection threads was monitored after inoculation of alfalfa with red- or green-tagged bacteria. Most threads were populated with single bacterial types. Mixed infections were present but gave mixed nodules less often than expected. These patterns are explained by a model describing bacterial growth during infection.

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Gao, Jian, Lindsie Jeffries, Kathleen E. Mach, et al. "A Multiplex Electrochemical Biosensor for Bloodstream Infection Diagnosis." SLAS TECHNOLOGY: Translating Life Sciences Innovation 22, no. 4 (2016): 466–74. http://dx.doi.org/10.1177/2211068216651232.

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Accurate and timely detection of bacterial pathogens will improve the clinical management of infections. Herein, we demonstrate an electrochemical biosensor that directly detects bacteria in human blood samples, resulting in the rapid diagnosis of a bloodstream infection. The multiplex biosensor detects the species-specific sequences of the 16S ribosomal RNA of bacteria for pathogen identification in physiological samples without preamplification. The analytical performance characteristics of the biosensor, including the limit of detection and probe cross-reactivity, are evaluated systematical

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Özdemir, Burcu, İpek Mumcuoğlu, Esragül Akıncı, İlkem Acar Kaya, Ahmet Sertçelik, and Hürrem Bodur. "Anaerop İnfeksiyon Saptanan Vakaların Klinik Özellikleri, Etkenlerin Tür Düzeyinde Dağılımı ve Anaerop Bakteremilerde Fatalite." Flora the Journal of Infectious Diseases and Clinical Microbiology 25, no. 4 (2020): 506–15. http://dx.doi.org/10.5578/flora.69469.

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Introduction: This study aimed to determine the distribution of anaerobic bacteria species, which are the causative agents of infection, in order to investigate the epidemiological and clinical characteristics of the cases and evaluate fatality in cases with an aerobic bacteremia. Materials and Methods: One hundred and twenty-five cases who were determined with 148 isolates of anaerobic bacteria were included into this study at Ankara Numune Training and Research Hospital Medical Microbiology Laboratory between January 2014-February 2018. The specimens requested to undergo anaerobic evaluation

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Yee, Rebecca, Yuting Yuan, Andreina Tarff, et al. "Eradication of Staphylococcus aureus Biofilm Infection by Persister Drug Combination." Antibiotics 11, no. 10 (2022): 1278. http://dx.doi.org/10.3390/antibiotics11101278.

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Staphylococcus aureus can cause a variety of infections, including persistent biofilm infections, which are difficult to eradicate with current antibiotic treatments. Here, we demonstrate that combining drugs that have robust anti-persister activity, such as clinafloxacin or oritavancin, in combination with drugs that have high activity against growing bacteria, such as vancomycin or meropenem, could completely eradicate S. aureus biofilm bacteria in vitro. In contrast, single or two drugs, including the current treatment doxycycline plus rifampin for persistent S. aureus infection, failed to

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LIU, CUICUI, and YUEQING GU. "NONINVASIVE OPTICAL IMAGING OF STAPHYLOCOCCUS AUREUS INFECTION IN VIVO USING AN ANTIMICROBIAL PEPTIDE FRAGMENT BASED NEAR-INFRARED FLUORESCENT PROBES." Journal of Innovative Optical Health Sciences 06, no. 03 (2013): 1350026. http://dx.doi.org/10.1142/s1793545813500260.

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The diagnosis of bacterial infections remains a major challenge in medicine. Optical imaging of bacterial infection in living animals is usually conducted with genetic reporters such as light-emitting enzymes or fluorescent proteins. However, there are many circumstances where genetic reporters are not applicable, and there is an urgent need for exogenous synthetic probes that can selectively target bacteria. Optical imaging of bacteria in vivo is much less developed than methods such as radioimaging and MRI. Furthermore near-infrared (NIR) dyes with emission wavelengths in the region of 650–9

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