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1

Anoun, Jihed, Mariem Ajmi, Salma Riahi, et al. "Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in bacterial infections: contributions to diagnostic strategies in a tertiary care hospital in Tunisia." F1000Research 13 (September 25, 2024): 978. http://dx.doi.org/10.12688/f1000research.146952.2.

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Background Bacterial infections continue to pose a global health challenge, driven by antibiotic resistance and septicemia. This study aimed to assess the diagnostic utility of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in bacterial infections versus non-infectious causes of inflammation. Methods A prospective study included 164 adult patients who were divided into two groups: a group of patients with confirmed bacterial infections and a second group of patients with other diagnoses (inflammatory pathologies, neoplasms, venous thromboembolic diseases, etc.). NL
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2

Anoun, Jihed, Mariem Ajmi, Salma Riahi, et al. "Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in bacterial infections: contributions to diagnostic strategies in a tertiary care hospital in Tunisia." F1000Research 13 (August 29, 2024): 978. http://dx.doi.org/10.12688/f1000research.146952.1.

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Background Bacterial infections continue to pose a global health challenge, driven by antibiotic resistance and septicemia. This study aimed to assess the diagnostic utility of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in bacterial infections versus non-infectious causes of inflammation. Methods A prospective study included 164 adult patients who were divided into two groups: a group of patients with confirmed bacterial infections and a second group of patients with other diagnoses (inflammatory pathologies, neoplasms, venous thromboembolic diseases, etc.). NL
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3

Markovic-Zivkovic, Bojana, Goran Bjelakovic, Aleksandar Nagorni, et al. "Bacterial infections in patients with liver cirrhosis and ascites." Srpski arhiv za celokupno lekarstvo 142, no. 9-10 (2014): 551–56. http://dx.doi.org/10.2298/sarh1410551m.

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Introduction. Bacterial infections are common complications and the cause of death in patients with cirrhosis and ascites. There is no standard method for a rapid and low-cost diagnosis, and its prognosis is poor. Objective. The aim of this study was to determine the etiology and frequency of bacterial infections in patients with liver cirrhosis of different etiology, and the influence of bacterial infections on the prognosis in patients with liver cirrhosis and ascites. Methods. Sixty-four patients with cirrhosis and ascites were included in the study. The diagnosis of spontaneous bacterial p
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4

AbdelRahman, Mona, Karim Selim, and Amany Adel. "Comparative Study Between the Sequencing of 16sRNA gene and Traditional Identification Methods of Some Bacterial Pathogens Associated with A Systemic Bacterial Infections from Diseased Poultry Flocks." Alexandria Journal of Veterinary Sciences 74, no. 1 (2022): 24. http://dx.doi.org/10.5455/ajvs.24347.

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Poultry health problems of chickens are usually accompanied by bacterial systemic infections causing severe losses in flocks, sick birds were systemically could be infected by several bacteria regardless of the clinical signs. 16s RNA sequence is a modern approach for the diagnosis of bacterial infection, especially of multiple causative agents. Ten field cases suffering from systemic infections have been examined for bacterial causes, using conventional isolation and 16S rRNA sequencing, The ten sequenced samples were compatible with the results of isolation; six samples were similar to E.col
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5

Liu, Benjamin M., Natella Y. Rakhmanina, Zhilong Yang, and Michael I. Bukrinsky. "Mpox (Monkeypox) Virus and Its Co-Infection with HIV, Sexually Transmitted Infections, or Bacterial Superinfections: Double Whammy or a New Prime Culprit?" Viruses 16, no. 5 (2024): 784. http://dx.doi.org/10.3390/v16050784.

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Epidemiologic studies have established that mpox (formerly known as monkeypox) outbreaks worldwide in 2022–2023, due to Clade IIb mpox virus (MPXV), disproportionately affected gay, bisexual, and other men who have sex with men. More than 35% and 40% of the mpox cases suffer from co-infection with HIV and sexually transmitted infections (STIs) (e.g., Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum, and herpes simplex virus), respectively. Bacterial superinfection can also occur. Co-infection of MPXV and other infectious agents may enhance disease severity, deteriorate outcomes
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Xu, Yin, Kelsi A. Smith, Ayako Hiyoshi, Fredrik Piehl, Tomas Olsson, and Scott Montgomery. "Hospital-diagnosed infections before age 20 and risk of a subsequent multiple sclerosis diagnosis." Brain 144, no. 8 (2021): 2390–400. http://dx.doi.org/10.1093/brain/awab100.

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Abstract The involvement of specific viral and bacterial infections as risk factors for multiple sclerosis has been studied extensively. However, whether this extends to infections in a broader sense is less clear and little is known about whether risk of a multiple sclerosis diagnosis is associated with other types and sites of infections such as the CNS. This study aims to assess if hospital-diagnosed infections by type and site before age 20 years are associated with risk of a subsequent multiple sclerosis diagnosis and whether this association is explained entirely by infectious mononucleo
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7

Nakamura, Shota, Norihiro Maeda, Ionut Mihai Miron, et al. "Metagenomic Diagnosis of Bacterial Infections." Emerging Infectious Diseases 14, no. 11 (2008): 1784–86. http://dx.doi.org/10.3201/eid1411.080589.

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8

Mukherjee, Adrish Kumar, Shivangi Baral, Smrutishree Mohapatro, Soumya Nayak, and Basanti Kumari Pathi. "Automated microbiological diagnosis of bloodstream infections." Journal of Integrative Medicine and Research 2, no. 4 (2024): 211–14. http://dx.doi.org/10.4103/jimr.jimr_7_24.

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Abstract: The term “bloodstream infection” (BSI) describes the existence of live microorganisms in the blood that have the potential to alter hemodynamic and clinical features, trigger an inflammatory response in the host, and have significant repercussions. Although viruses, fungi, bacteria, and protozoa can all cause bloodstream infections (BSIs), bacteria are the primary cause. When treating patients, it is critical to identify the bacteriological agent and its antibiotic susceptibility pattern as soon as possible. Blood samples from suspected BSI patients are run through automated culture
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9

Fernández, Javier, Juan Acevedo, Reiner Wiest, et al. "Bacterial and fungal infections in acute-on-chronic liver failure: prevalence, characteristics and impact on prognosis." Gut 67, no. 10 (2017): 1870–80. http://dx.doi.org/10.1136/gutjnl-2017-314240.

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Bacterial infection is a frequent trigger of acute-on-chronic liver failure (ACLF), syndrome that could also increase the risk of infection. This investigation evaluated prevalence and characteristics of bacterial and fungal infections causing and complicating ACLF, predictors of follow-up bacterial infections and impact of bacterial infections on survival.Patients407 patients with ACLF and 235 patients with acute decompensation (AD).Results152 patients (37%) presented bacterial infections at ACLF diagnosis; 46%(n=117) of the remaining 255 patients with ACLF developed bacterial infections duri
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10

Bendig, Donald W. "The Differential Diagnosis of Sterile Pyuria in Pediatric Patients: A Review." Global Pediatric Health 8 (January 2021): 2333794X2199371. http://dx.doi.org/10.1177/2333794x21993712.

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Sterile pyuria is a common finding in pediatric patients. Literature describing the diagnoses as well as clinical characteristics of children with sterile pyuria is lacking. This review was performed to establish an evidence-based approach to the differential diagnosis by way of an extensive literature search. The definition of pyuria is inconsistent. The various causes of pediatric sterile pyuria identified were classified as either Infectious or Non-Infectious. Sub-categories of Infectious causes include: Viral Infection, Bacterial Infection, Other Infections (tuberculosis, fungal, parasitic
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11

Hung, Yuan-Pin, Yu-Fon Chen, Pei-Jane Tsai, I.-Hsiu Huang, Wen-Chien Ko, and Jeng-Shiung Jan. "Advances in the Application of Nanomaterials as Treatments for Bacterial Infectious Diseases." Pharmaceutics 13, no. 11 (2021): 1913. http://dx.doi.org/10.3390/pharmaceutics13111913.

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Bacteria-targeting nanomaterials have been widely used in the diagnosis and treatment of bacterial infectious diseases. These nanomaterials show great potential as antimicrobial agents due to their broad-spectrum antibacterial capacity and relatively low toxicity. Recently, nanomaterials have improved the accurate detection of pathogens, provided therapeutic strategies against nosocomial infections and facilitated the delivery of antigenic protein vaccines that induce humoral and cellular immunity. Biomaterial implants, which have traditionally been hindered by bacterial colonization, benefit
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12

Zou, Pengfei, Wen-Ting Chen, Tongyi Sun, Yuanyuan Gao, Li-Li Li, and Hao Wang. "Recent advances: peptides and self-assembled peptide-nanosystems for antimicrobial therapy and diagnosis." Biomaterials Science 8, no. 18 (2020): 4975–96. http://dx.doi.org/10.1039/d0bm00789g.

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Bacterial infections, especially the refractory treatment of drug-resistant bacteria, are one of the greatest threats to human health. Self-assembling peptide-based strategies can specifically detect the bacteria at the site of infection in the body and kill it.
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13

Stetsko, T. I. "BACTERIAL INTESTINAL INFECTIONS OF SWINE." Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology 23, no. 1 (2022): 161–83. http://dx.doi.org/10.36359/scivp.2022-23-1.23.

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Bacterial intestinal infections are one of the main diseases in pigs of different ages. Bacterial diseases of the pig digestive tract lead to significant economic losses due to high mortality, reduced growth, treatment and prevention costs.
 The main bacterial intestinal infections of pigs are anaerobic enterotoxemia (clostridiosis), colibacillosis, intestinal salmonellosis, dysentery, proliferative enteropathy (ileitis).
 Anaerobic enterotoxemia of pigs is an acute toxic-infectious disease mainly of newborn piglets, caused by pathogenic bacteria of the genus Clostridium and characte
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14

Milhem, Zaki, Paul Chiroi, Andreea Nutu, et al. "Non-Coding RNAs and Reactive Oxygen Species–Symmetric Players of the Pathogenesis Associated with Bacterial and Viral Infections." Symmetry 13, no. 7 (2021): 1307. http://dx.doi.org/10.3390/sym13071307.

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Infections can be triggered by a wide range of pathogens. However, there are few strains of bacteria that cause illness, but some are quite life-threatening. Likewise, viral infections are responsible for many human diseases, usually characterized by high contagiousness. Hence, as bacterial and viral infections can both cause similar symptoms, it can be difficult to determine the exact cause of a specific infection, and this limitation is critical. However, recent scientific advances have geared us up with the proper tools required for better diagnoses. Recent discoveries have confirmed the in
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15

Shamaileh, Lelas, Sirui Ma, and Matthew Weinstock. "Infectious Complications in Patients with Hemophagocytic Lymphohistiocytosis: A Single Center Experience." Blood 144, Supplement 1 (2024): 5367. https://doi.org/10.1182/blood-2024-194180.

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Background: Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome characterized by fever, cytopenias, and activated macrophages in hemopoietic organs. HLH is commonly associated with underlying conditions such as infection, autoimmune disease, malignancy, or immunosuppressive therapy. Management of HLH includes treatment directed at the specific trigger, suppression of maladaptive cytokines, and inhibition of T cell and macrophage proliferation. While there has been a dramatically improved survival rate with the HLH-94 protocol, mortality remains high, with reports rang
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16

Stanković, Stefan, and Irena Đunić. "Bacterial infections in patients in allogenic stem cell transplantation programs." Srpski medicinski casopis Lekarske komore 3, no. 1 (2022): 45–54. http://dx.doi.org/10.5937/smclk3-35312.

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Introduction: Bacterial infections are common in patients enrolled in allogenic hematopoietic stem cell transplantation. Infections are the most common cause of illness and mortality in transplanted patients. The most common pathogens are Staphylococcus and Enterobacteriaceae, causing 25% of bacterial infections, each, followed by Enterococcus andP. aeruginosa. Aim: The aim of the paper is calculating the frequency of bacterial infections in patients enrolled in allogenic hematopoietic stem cell transplantation, at the Clinic for Hematology of the University Clinical Center of Serbia, as well
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17

Gao, Jian, Lindsie Jeffries, Kathleen E. Mach, et al. "A Multiplex Electrochemical Biosensor for Bloodstream Infection Diagnosis." SLAS TECHNOLOGY: Translating Life Sciences Innovation 22, no. 4 (2016): 466–74. http://dx.doi.org/10.1177/2211068216651232.

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Accurate and timely detection of bacterial pathogens will improve the clinical management of infections. Herein, we demonstrate an electrochemical biosensor that directly detects bacteria in human blood samples, resulting in the rapid diagnosis of a bloodstream infection. The multiplex biosensor detects the species-specific sequences of the 16S ribosomal RNA of bacteria for pathogen identification in physiological samples without preamplification. The analytical performance characteristics of the biosensor, including the limit of detection and probe cross-reactivity, are evaluated systematical
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18

Jaffe, Ian S., Anja K. Jaehne, Eugenia Quackenbush, et al. "1218. Comparing the Diagnostic Accuracy of Clinician Judgement to a Novel Host Response Diagnostic for Acute Respiratory Illness." Open Forum Infectious Diseases 7, Supplement_1 (2020): S630. http://dx.doi.org/10.1093/ofid/ofaa439.1403.

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Abstract Background Discriminating bacterial and viral infections remains clinically challenging. The resulting antibacterial misuse contributes to antimicrobial resistance. Host gene expression-based tests are a promising strategy to discriminate of bacterial and viral infections, but their potential clinical utility has not yet been evaluated. Methods A host gene expression biosignature was measured using either qRT-PCR or microarray in 683 ED subjects with suspected infection. Based on chart reviews, we recorded clinical diagnosis as defined both by the provider assessment and by the provid
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19

Jia, Huiqiong, Mohamed S. Draz, and Zhi Ruan. "Functional Nanomaterials for the Detection and Control of Bacterial Infections." Current Topics in Medicinal Chemistry 19, no. 27 (2019): 2449–75. http://dx.doi.org/10.2174/1568026619666191023123407.

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Infections with multidrug-resistant bacteria that are difficult to treat with commonly used antibiotics have spread globally, raising serious public health concerns. Conventional bacterial detection techniques are time-consuming, which may delay treatment for critically ill patients past the optimal time. There is an urgent need for rapid and sensitive diagnosis and effective treatments for multidrug-resistant pathogenic bacterial infections. Advances in nanotechnology have made it possible to design and build nanomaterials with therapeutic and diagnostic capabilities. Functional nanomaterials
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Budzyńska, Anna, Agnieszka Kaczmarek, and Eugenia Gospodarek. "Molecular diagnosis of bacterial bloodstream infections." Forum Zakażeń 4, no. 2 (2013): 111–17. http://dx.doi.org/10.15374/fz2013025.

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21

Deepthi, KrishnanNair Geetha, and Solai Ramatchandirane Prabagaran. "Ocular bacterial infections: Pathogenesis and diagnosis." Microbial Pathogenesis 145 (August 2020): 104206. http://dx.doi.org/10.1016/j.micpath.2020.104206.

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22

Noviello, Stephanie, and David Huang. "The Basics and the Advancements in Diagnosis of Bacterial Lower Respiratory Tract Infections." Diagnostics 9, no. 2 (2019): 37. http://dx.doi.org/10.3390/diagnostics9020037.

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Lower respiratory tract infections (LRTIs) are the leading infectious cause of death and the sixth-leading cause of death overall worldwide. Streptococcus pneumoniae, with more than 90 serotypes, remains the most common identified cause of community-acquired acute bacterial pneumonia. Antibiotics treat LRTIs with a bacterial etiology. With the potential for antibiotic-resistant bacteria, defining the etiology of the LRTI is imperative for appropriate patient treatment. C-reactive protein and procalcitonin are point-of-care tests that may differentiate bacterial versus viral etiologies of LRTIs
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23

Wang, Weiying, and Shu Hua Li. "Use of common blood parameters for the differential diagnosis of childhood infections." PLOS ONE 17, no. 9 (2022): e0273236. http://dx.doi.org/10.1371/journal.pone.0273236.

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Background Routine laboratory investigations are not rapidly available to assist clinicians in the diagnosis of pediatric acute infections. Our objective was to evaluate some common blood parameters and use them for the differential diagnosis of childhood infections. Methods This retrospective study was conducted between October 2019 and September 2020 at Guangzhou Women and Children’s Medical Center, China. We performed blood tests in patients infected with DNA viruses (n = 402), RNA viruses (n = 602), gram-positive organisms (G+; n = 421), gram-negative organisms (G−; n = 613), or Mycoplasma
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Mahboobi, Bashir Ahmad, Zarghoon Tareen, Sharafudin Resha, Bilal Ahmad Rahimi, and Enayattullah Mohammadi. "Sensitivity Pattern in Children Respiratory Bacterial Infections." Razi International Medical Journal 4, no. 2 (2024): 65–79. https://doi.org/10.56101/rimj.v4i2.161.

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Background: Bacterial respiratory infections are a major health concern, especially in underdeveloped and developing countries. This study aims to evaluate the prevalence of Gram-negative and Gram-positive bacteria in respiratory infections and assess the efficacy of antibiotics. Methods: A prospective, observational study was conducted from July 2010 to July 2011. Patients with respiratory infections were categorized by age, bacterial pathogen, disease type, and season of infection. Diagnostic methods, including throat swabs, blood cultures, and antibiograms, were used to identify pathogens a
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Gleeson, David. "Bacterial skin infections." InnovAiT: Education and inspiration for general practice 12, no. 8 (2019): 454–58. http://dx.doi.org/10.1177/1755738019849079.

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Every year, around 24% of the population consults their GP about a skin problem. Bacterial skin infections, especially in the paediatric and elderly populations, are common and some are potentially life-threatening. The most common bacterial pathogens associated with skin infections are Staphylococcus aureus and Staphylococcus pyogenes. This article will cover diagnosis and management of the most common skin infections, high-lighting important features of potentially lethal presentations requiring hospitalisation. Infections affecting superficial layers of the skin, deeper layers, and accessor
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Focak, M., E. Haskovic, D. Suljevic, and A. Zahirovic. "Comparative Evaluation of Biochemical Parameters During Urinary Infection in Maltese and Belgian Shepherd Dogs." Cercetari Agronomice in Moldova 50, no. 3 (2017): 107–14. http://dx.doi.org/10.1515/cerce-2017-0030.

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Abstract Urinary tract infections can be uncomfortable, painful and even dangerous for most dog breeds. Clinical signs are often nonspecific and insufficient for diagnosis. Urinalysis in combination with biochemical parameters and urine culture is the best combination of clinical findings for diagnosis of urinary tract infections. The incidence of urinary tract infections in dogs population is growing and 27% of dogs develop an urinary tract infection through their life. Urinary infections occur more often in the elderly than in younger dogs. More than 70% of all urinary tract infections are i
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Rankin, Danielle A., Nikhil K. Khankari, Zaid Haddadin, et al. "Antibiotic use for respiratory syncytial virus in the Middle East: A surveillance study in hospitalized Jordanian children." PLOS ONE 16, no. 11 (2021): e0260473. http://dx.doi.org/10.1371/journal.pone.0260473.

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Introduction In developing countries where point-of-care testing is limited, providers rely on clinical judgement to discriminate between viral and bacterial respiratory infections. We performed a cross-sectional cohort study of hospitalized Jordanian children to evaluate antibiotic use for respiratory syncytial virus (RSV) infections. Materials and methods Admitting diagnoses from a prior viral surveillance cohort of hospitalized Jordanian children were dichotomized into suspected viral-like, non-pulmonary bacterial-like, and pulmonary bacterial-like infection. Stratifying by sex, we performe
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Malakhov, Alexander B., Alena Iu Sedova, Natalia G. Kolosova, Pavel V. Berezhanskiy, and Tatiana A. Gutyrchik. "Viral and bacterial lung infections in children: algorithms for diagnosis and therapy. A review." Consilium Medicum 25, no. 8 (2023): 505–11. http://dx.doi.org/10.26442/20751753.2023.8.202345.

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Community-acquired pneumonia is among the most common lower respiratory infections. The main etiological factors of lower respiratory infections are bacteria, viruses, and combinations. Pediatricians are increasingly faced with the problem of treating patients with infections caused by multidrug-resistant bacteria and viral lung infections; therefore, differential diagnosis of viral and bacterial lung infections in children is relevant. Significant progress has been made in diagnosing, treating, and preventing pneumonia in children; however, some issues require improvement in approaches to the
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Mbuvi, Christine Musungi, Boniface Nzioki Musila, and Anthony Kebira Nyamache. "Urogenital Infections Among Women Attending Mwingi Hospital, Kitui County, Kenya: Safeguarding Antibiotics Through Microbiological Diagnosis." East African Health Research Journal 8, no. 1 (2024): 99–105. https://doi.org/10.24248/eahrj.v8i1.764.

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ABSTRACT Background: Urogenital infections pose a considerable public health threat, as almost half of women will experience urinary and reproductive system infections at some point in their lives. However, the urogenital infection burden is often not clear in some regions. Nevertheless, the misuse of antimicrobial agents, including self-prescription, has increased widespread antimicrobial resistance, limiting treatment benefits. Therefore, this study aimed to identify the various urogenital infections, associated risk factors, and profile the bacterial isolates, and assess their antibiotic re
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Fischer, Petra, Stanca Pandrea, Crina Grigoras, et al. "Blood Metabolomic Signatures to Identify Bacterial Infection in Patients with Decompensated Cirrhosis." Journal of Gastrointestinal and Liver Diseases 31, no. 1 (2022): 40–47. http://dx.doi.org/10.15403/jgld-4034.

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Background and Aims: Bacterial infections are associated with high mortality rates in patients with decompensated cirrhosis. Early diagnosis with the available diagnostic tools is challenging. Metabolomics is a novel technique with a widespread application in hepatology. The aims of our study were to find new biomarkers for decompensated cirrhosis and for those with overlapping bacterial infections.
 Methods: 43 patients with compensated and 54 patients with decompensated cirrhosis were enrolled in the study. In patients with decompensation, a complete infectious workup was performed at a
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Mariana, Partida Rodríguez, Saldaña Peña Sergio, Alin Franco Espinosa Karen, Barrios Vázquez Michelle, and Arias Mendoza Alejandro. "Impetigo: Diagnosis and Treatment at the First Level of Care." International Journal Of Medical Science And Clinical Research Studies 02, no. 11 (2022): 1251–52. https://doi.org/10.5281/zenodo.7313548.

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Bacterial skin infections are processes that are produced by the direct or indirect presence of different bacteria, which can infect the skin and/or its annexes. Knowledge of these processes is relevant because, although there are some unimportant and exclusively local infections, there are others that can lead to systemic diseases and lead the patient to a septic state and, if complicated, death. This work tries to expose the clinic and the characteristics of impetigo on the subject of a case. Bacterial infections mainly affect the leg and foot, however face involvement is important due to it
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Dr., SIBI DAS, SETHI DAS Dr., SILVANOSE Dr., and JIBIN V. GLADSTON Dr. "Post-COVID-19 Bacterial Pneumonia: Diagnosis and Treatment." Genesis Journal of Medicine and Surgery v1, no. 2 (2023): 12. https://doi.org/10.5281/zenodo.7810162.

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COVID-19 patients, particularly those with severe symptoms, are more susceptible to developing secondary bacterial infections due to weakened immune systems. Antibiotics are often used to treat these infections, but the overuse of antibiotics has led to the emergence of antibiotic-resistant bacterial strains. <em>Streptococcus pneumoniae</em>, <em>Staphylococcus aureus</em>, <em>Haemophilus influenzae</em>, <em>Klebsiella pneumoniae</em>, <em>Acinetobacter baumannii</em>, <em>Escherichia coli</em>, <em>Pseudomonas aeruginosa</em>, and <em>Legionella pneumophila</em> are some of the bacteria co
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OLECH, MONIKA, and EWA PAŹDZIOR. "Detection of bacterial fish pathogens by MALDI-TOF MS- state of the art." Medycyna Weterynaryjna 80, no. 4 (2024): 257–63. http://dx.doi.org/10.21521/mw.6889.

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A key element in the diagnosis of bacterial infections in fish is the rapid identification of the etiological agent of the disease and drug resistance testing. Traditional methods of identifying the bacteria that cause fish diseases are often slow and/or expensive. MALDI-TOF MS is a well-established, rapid, accurate and cost-effective method based on protein profile analysis for the identification of bacterial pathogens in human and veterinary laboratories, and has now found application in the diagnosis of bacterial infections in fish. The method identifies microorganisms based on their protei
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Todorov, Iliyan, Margarita Gospodinova, Yana Bocheva, and Gergana Popcheva. "Serum amyloid A protein in the course of infectious mononucleosis." Therapeutic Advances in Infectious Disease 6 (January 2019): 204993611881120. http://dx.doi.org/10.1177/2049936118811208.

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Background: Serum amyloid A (SAA) protein is a major acute phase protein. Increased concentrations have been reported in many inflammatory diseases. In bacterial infections, high levels correlate with those of C-reactive protein (CRP). In viral infections, where CRP changes are weaker, SAA is of value for establishing early diagnosis, monitoring the severity, and the evolution of the disease. Objective: Evaluation of SAA as a marker for diagnosis of infectious mononucleosis, including severe forms. Material and methods: A total of 31 patients with non-complicated and severe, complicated infect
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Rebouças, Aurea do Socorro Santos, Ana Flávia Borges Carvalho e. Silva, Isadora de Moura Batz, et al. "Throat infection: causes, symptoms, and diagnosis." International Health Sciences Review 1, no. 3 (2025): 30–36. https://doi.org/10.70164/ihsr.v1i3.13.

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Throat infection, also known as pharyngitis or tonsillitis, is a common condition that affects individuals of all ages, being especially prevalent among children and adolescents. It can be caused by viruses or bacteria, with Streptococcus pyogenes standing out as the main bacterial agent. Symptoms include pain when swallowing, fever, malaise, and oropharyngeal inflammation. Although often self-limiting, the infection can lead to complications if not properly treated. Accurate diagnosis and appropriate management are essential to relieve symptoms, prevent adverse outcomes, and avoid the indiscr
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Toofani Milani, Attabak, Mahshid Mohammadian, Sadegh Rostaminasab, Roghayeh Paribananaem, Zohre Ahmadi, and Azim Akbarzadeh Khiyavi. "Procalcitonin Testingreduce Unnecessary Antibiotic Use in Bacterial Infection." Asian Pacific Journal of Environment and Cancer 2, no. 1 (2019): 1–3. http://dx.doi.org/10.31557/apjec.2019.2.1.1.

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Conventional diagnostic test have limitations to deferential diagnosis in clinical suspicion ofbacterial infection cases, that in some cases lead to inappropriate antibiotic therapy and increases antibiotic resistance. A new diagnostic insight is procalcitonin (PCT) test to improve diagnosis of bacterial infections and to guide antibiotic therapy. Serum PCT levels are of useful test as a biomarker in patients with bacterial infections for several reasons. Initial rise of PCT levels due to bacterial infection, subsequent sequential PCT levels can be used to assess the effectiveness and duration
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Toofani Milani, Attabak, Mahshid Mohammadian, Sadegh Rostaminasab, Roghayeh Paribananaem, Zohre Ahmadi, and Azim Akbarzadeh Khiyavi. "Procalcitonin Testingreduce Unnecessary Antibiotic Use in Bacterial Infection." Asian Pacific Journal of Environment and Cancer 2, no. 1 (2019): 1–3. http://dx.doi.org/10.31557/apjec.2019.2.1.1-3.

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Conventional diagnostic test have limitations to deferential diagnosis in clinical suspicion ofbacterial infection cases, that in some cases lead to inappropriate antibiotic therapy and increases antibiotic resistance. A new diagnostic insight is procalcitonin (PCT) test to improve diagnosis of bacterial infections and to guide antibiotic therapy. Serum PCT levels are of useful test as a biomarker in patients with bacterial infections for several reasons. Initial rise of PCT levels due to bacterial infection, subsequent sequential PCT levels can be used to assess the effectiveness and duration
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Shumytskyi, A. V., O. A. Burka, and T. M. Tutchenko. "Criteria for the diagnosis of infectious lesions of the lower urinary tract and pelvic organs." HEALTH OF WOMAN, no. 10(146) (December 30, 2019): 101–4. http://dx.doi.org/10.15574/hw.2019.146.101.

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Urinary tract infections are the third most prevalent in humans after respiratory and gastrointestinal infections. In fact, bacterial infections of the urinary tract are the most common cause of both hospital and community hospital infections in patients. Pelvic inflammatory diseases (PID) are infectious inflammatory diseases of the upper female genital tract. In addition, the infection can also spread to the abdomen. The classic patient with a high risk of developing a PMTCT is, first and foremost, a woman with multiple sexual partners and unprotected sex. Key words: urethritis, PID, laborato
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Al-Khateeb, Anfal Izaldien. "Diarrhea Causative For Resident Children in General Zahraa Hospital under age group (1 month to 6 years )." Journal of Wasit for Science and Medicine 1, no. 2 (2022): 35–44. http://dx.doi.org/10.31185/jwsm.9.

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This study was undertaken around diarrhea causative for resident children in general Al_Zahraa Hospital under (1 month to 6 years ) during time period from 1/8/2005 to 1/11/2005. In order to determine diarrhea causative and assistance agents to infection occurrence, check have been perform for one hundred samples involve water and food quality which given to child depend on sterilization and sanitation , state (15 samples) out (100 samples) were used the water of streams nearthier house ., (15 samples) they use sterilize water . We have been diagnosis 95 state out I hundred recorded bacterial
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Osmanov, I. M., O. N. Solodovnikova, S. N. Borzakova, T. V. Sbrodova, P. N. Iliasova та S. N. Novoselova. "Поражение пищеварительного тракта как проявление COVID-19 у ребенка 4 лет". Doctor.Ru 20, № 3 (2021): 56–59. http://dx.doi.org/10.31550/1727-2378-2021-20-3-56-59.

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Objective of the Paper: To represent a case of the novel coronavirus infection COVID-19 in a 4-year-old child with isolated bowel damage. Key Points. COVID-19 impacts several systems and organs. Usually, children have mild or asymptomatic disease. Clinical manifestations of COVID-19 in children can be damage not only of respiratory tract, but also of GIT, requiring differential diagnosis of enteric infections (both viral and bacterial). Prompt diagnosis of COVID-19 is essential for antiepidemic measures and suppression an infectious process. The case shows challenges faced by clinicians when d
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Cho, Steve Y., Steven P. Rowe, Sanjay K. Jain, et al. "Evaluation of Musculoskeletal and Pulmonary Bacterial Infections With [124I]FIAU PET/CT." Molecular Imaging 19 (January 1, 2020): 153601212093687. http://dx.doi.org/10.1177/1536012120936876.

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Purpose: Imaging is limited in the evaluation of bacterial infection. Direct imaging of in situ bacteria holds promise for noninvasive diagnosis. We investigated the ability of a bacterial thymidine kinase inhibitor ([124I]FIAU) to image pulmonary and musculoskeletal infections. Methods: Thirty-three patients were prospectively accrued: 16 with suspected musculoskeletal infection, 14 with suspected pulmonary infection, and 3 with known rheumatoid arthritis without infection. Thirty-one patients were imaged with [124I]FIAU PET/CT and 28 with [18F]FDG PET/CT. Patient histories were reviewed by a
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Fu, Xiao-Hong, Huan-Xiang Feng, Qian Huang, and Wei Gou. "Pneumonia in an elderly Tibetan male caused by Shewanella algae: A case report." Medicine 103, no. 32 (2024): e39197. http://dx.doi.org/10.1097/md.0000000000039197.

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Rationale: Shewanella algae are Gram-negative bacteria that are widely found in aquatic habitats and rarely cause lung infections in inland areas. Patient concerns: Cough with light-yellow phlegm for 2 weeks. Diagnoses: The final diagnosis was bacterial pneumonia. Interventions: The patient was treated with ceftazidime (2 g, every 12 h) for 1 week. Outcomes: The patient’s lung infection improved and he was discharged. Lessons: This case highlights a rare occurrence of lung infection caused by Shewanella algae in elderly Tibetan men residing in non-marine environments.
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Rantakokko-Jalava, Kaisu, Simo Nikkari, Jari Jalava, et al. "Direct Amplification of rRNA Genes in Diagnosis of Bacterial Infections." Journal of Clinical Microbiology 38, no. 1 (2000): 32–39. http://dx.doi.org/10.1128/jcm.38.1.32-39.2000.

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ABSTRACT A broad-range bacterial PCR targeting rRNA genes (rDNAs) was used to directly analyze 536 clinical samples obtained from 459 hospitalized patients during a 4-year study period. The molecular diagnosis based on DNA sequencing of the PCR product was compared to that obtained by bacterial culture. The bacteriological diagnosis was concordant for 447 (83%) specimens. Broad-range rDNA PCR was the only method that yielded an etiologic diagnosis for 11 (2.4%) of 459 patients. Compared to culture and clinical assessment, the sensitivity of the PCR method combined with sequencing was 74.2%, an
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Lilius, Esa-Matti, and Jari Nuutila. "Bacterial Infections, DNA Virus Infections, and RNA Virus Infections Manifest Differently in Neutrophil Receptor Expression." Scientific World Journal 2012 (2012): 1–7. http://dx.doi.org/10.1100/2012/527347.

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Treating viral illnesses or noninfective causes of inflammation with antibiotics is ineffective and contributes to the development of antibiotic resistance, toxicity, and allergic reactions, leading to increasing medical costs. A major factor behind unnecessary use of antibiotics is, of course, incorrect diagnosis. For this reason, timely and accurate information on whether the infection is bacterial in origin would be highly beneficial. In this paper we will present our recent studies on the expression of opsonin receptors on phagocytes. The analysis of the expression levels of FcγRI, CR1, an
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Bartlett, John G. "Diagnosis of Bacterial Infections of the Lung." Clinics in Chest Medicine 8, no. 1 (1987): 119–34. http://dx.doi.org/10.1016/s0272-5231(21)00471-8.

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Wiedermann, Franz J., Petra Innerhofer, Josef Margreiter, Dietmar Fuchs, and Wolfgang Schobersberger. "Procalcitonin and Neopterin in Infectious Diseases." Pteridines 10, no. 3 (1999): 125–32. http://dx.doi.org/10.1515/pteridines.1999.10.3.125.

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Summary Procalcitonin, a new inflammation parameter, has been shown to be markedly increased in patients with severe bacterial and parasitic infections, septic shock, and multiple organ failure. In contrast, in severe viral infections or inflammatory reactions of non-infectious origin (e.g. toxic acute respiratory distress syndrome or toxic pancreatitis) as well as in autoimmune disorders, there is little or moderate increase of procalcitonin serum levels. Therefore procalcitonin may be used for diHerential diagnosis of bacterial versus non-bacterial inflammation. Furthermore, procaicitonin co
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Xiang, Lingchao, Ozioma Udochukwu Akakuru, Chen Xu, and Aiguo Wu. "Harnessing the Intriguing Properties of Magnetic Nanoparticles to Detect and Treat Bacterial Infections." Magnetochemistry 7, no. 8 (2021): 112. http://dx.doi.org/10.3390/magnetochemistry7080112.

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Infections caused by pathogenic bacteria, especially multidrug-resistant bacteria, have become a serious worldwide public health problem. Early diagnosis and treatment can effectively prevent the adverse effects of such infections. Therefore, there is an urgent need to develop effective methods for the early detection, prevention, and treatment of diseases that are caused by bacterial infections. So far, magnetic material nanoparticles (MNPs) have been widely used in the detection and treatment of bacterial infections as detection agents and therapeutics. Therefore, this review describes the r
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Razak, Kamarul Arifin Abdul, Terence Michal Dass, Tan Weng Liang, Yogeshwarran Nadeson, and Karenjit Kaur. "Crab bite causing shewanella putrefaciens infection: Introduction to a possibly deadly and emerging threat." Orthopaedic Journal of Sports Medicine 8, no. 5_suppl5 (2020): 2325967120S0004. http://dx.doi.org/10.1177/2325967120s00046.

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Shewanella species are gram-negative bacteria found in warm, temperate regions and are normal microflora of the marine environment1. Human infections are unusual and have a restricted geographic distribution. Presentation: A 45 years old lady was bitten by a crab while preparing to cook it. She developed fever and swelling of the right thumb with hemoserous discharge and blackish discolouration.Upon examination, the thumb was erythematous and swollen with a hematoma filled blister formation over the dorsal aspect. Deblistering was done and fluid samples were sent for culture and sensitivity wh
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Gerace, Elisabetta, Giuseppe Mancuso, Angelina Midiri, Stefano Poidomani, Sebastiana Zummo, and Carmelo Biondo. "Recent Advances in the Use of Molecular Methods for the Diagnosis of Bacterial Infections." Pathogens 11, no. 6 (2022): 663. http://dx.doi.org/10.3390/pathogens11060663.

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Infections caused by bacteria have a major impact on public health-related morbidity and mortality. Despite major advances in the prevention and treatment of bacterial infections, the latter continue to represent a significant economic and social burden worldwide. The WHO compiled a list of six highly virulent multidrug-resistant bacteria named ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) responsible for life-threatening diseases. Taken together with Clostridioides difficile, Escherichia c
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Akwah, Lilian, Gonsu Kamga Hortense, E. Lyonga Mbamyah Emilia, et al. "Utility of Procalcitonin Over C-Reactive Protein and WBC as an Early and Rapid Diagnostic Marker of Bacterial Infections in Febrile Patients with or no Hemoculture Results as Gold Standard in a Malaria Endemic Zone of Cameroon." Utility of Procalcitonin Over C-Reactive Protein and WBC as an Early and Rapid Diagnostic Marker of Bacterial Infections in Febrile Patients with or no Hemoculture Results as Gold Standard in a Malaria Endemic Zone of Cameroon 01, no. 07 (2021): 163–70. https://doi.org/10.47191/ijmscrs/v1-i7-03,.

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Background &amp; objectives: Early identification of bacterial infection in patients with fever is important for prompt and specific treatment. However, the available biomarkers such as C-reactive protein (CRP) and leukocyte counts are not specific to bacterial diagnosis. This study aimed to assess the diagnostic value of procalcitonin (PCT) over CRP and leukocyte counts for bacterial infection screening in febrile patients while awaiting their hemoculture results, which takes up to 7 Days before results are available though it is the gold standard for the diagnosis of bacterial infections. Me
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