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Relevant bibliographies by topics / BAG-S53P4

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Journal articles

Academic literature on the topic 'BAG-S53P4'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "BAG-S53P4"

1

Coraça-Huber, Débora, Manfred Fille, Johann Hausdorfer, David Putzer, and Michael Nogler. "Efficacy of Antibacterial Bioactive Glass S53P4 Against S. aureus Biofilms Grown on Titanium Discs In Vitro." Journal of Orthopedic Research 32 (September 25, 2013): 175–77. https://doi.org/10.1002/jor.22463.

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ABSTRACT: We evaluated the effectiveness of different sizes of bioactive glass S53P4 against Staphylococcus aureus biofilms grown on metal discs in vitro. S. aureus biofilms were cultivated on titanium discs. BAG-S53P4 (0.5–0.8mm and <45 mm) were placed in contact with the discs containing biofilms. Glass beads (0.5mm) were used as a control. After each interval, the pH from each sample was measured. Colony forming units were counted for the biofilm recovery verification. In parallel, we tested the activity of bioactive glass against S. aureus planktonic cells. We found that BAG-S53P4

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2

Björkenheim, R., E. Jämsen, E. Eriksson, et al. "Sintered S53P4 bioactive glass scaffolds have anti-inflammatory properties and stimulate osteogenesis in vitro." European Cells and Materials 41 (January 3, 2021): 15–30. http://dx.doi.org/10.22203/ecm.v041a02.

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Bioactive glasses (BAG) are used as bone-graft substitutes in orthopaedic surgery. A specific BAG scaffold was developed by sintering BAG-S53P4 granules. It is hypothesised that this scaffold can be used as a bone substitute to fill bone defects and induce a bioactive membrane (IM) around the defect site. Beyond providing the scaffold increased mechanical strength, that the initial inflammatory reaction and subsequent IM formation can be enhanced by coating the scaffolds with poly(DL-lactide-co-glycolide) (PLGA) is also hypothesised. To study the immunomodulatory effects, BAG-S53P4 (± PLGA) sc

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3

Malat, Tarek Al, Martin Glombitza, Janosch Dahmen, Peter-Michael Hax, and Eva Steinhausen. "The Use of Bioactive Glass S53P4 as Bone Graft Substitute in the Treatment of Chronic Osteomyelitis and Infected Non-Unions – a Retrospective Study of 50 Patients." Zeitschrift für Orthopädie und Unfallchirurgie 156, no. 02 (2018): 152–59. http://dx.doi.org/10.1055/s-0043-124377.

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Abstract Background Treatment of chronic osteomyelitis (COM) remains challenging and often results in large bone defects. Dead space management and proper defect filling are essential for successful treatment. Bioactive glass S53P4 (BAG-S53P4) is an anorganic bone graft substitute with antibacterial, osteoconductive, osteostimulative and angiogenic properties. The aim of our study was to analyse the outcome of patients with COM and infected non-unions, whose bone defects were filled with BAG-S53P4. Material and Methods In this retrospective study (07/13 – 02/16), we analysed all patients with

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4

Putzer, David, Johannes Fuchs, Débora Coraça-Huber, Christoph Ammann, Michael Liebensteiner, and Michael Nogler. "BAG-S53P4 as an Additive to Bone Allografts: A Laboratory Study Using an Uniaxial Compression Test." J Orthop Res 33 (June 12, 2015): 1875–79. https://doi.org/10.1002/jor.22953.

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ABSTRACT: We want to address the clinical issue of too sparse supply of allograft in total hip replacement and ambitions of controlling the grain size distribution. Bioglass BAG-S53P4 was evaluated as a bone graft additive to chemically treated allografts with controlled grain size distribution. Allografts were chemically cleaned (CG) and mixed with BAG-S53P4 additive (BG) for comparison. All samples were compacted with a dropped weight apparatus and then underwent a uniaxial compression test. The yield limit was determined by a uniaxial compression test and density was recorded while flowabil

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Dell’Aquila, Adriana Macedo, Gabriela Nagy Baldy dos Reis, Gabriel Trova Cuba, et al. "Outcome and Predictors of Treatment Failure in Chronic Osteomyelitis Using Bioactive Glass Granules and Putty Formulations." Antibiotics 12, no. 12 (2023): 1720. http://dx.doi.org/10.3390/antibiotics12121720.

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Background: The aim of this study is to evaluate the outcome of patients with cavitary chronic osteomyelitis undergoing adjuvant treatment with bioactive glass (BAG) S53P4 and identify the independent risk factors (RFs) for recurrence in 6- and 12-month patient follow-up. Methods: A retrospective, multicentre observational study conducted in tertiary specialised hospitals among patients undergoing the surgical treatment of chronic cavitary osteomyelitis using BAG-S53P4 in a granule and/or putty formulation to assess the clinical outcome and RFs for failure in 6- and 12-month patient follow-up.

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van Gestel, Nicole A. P., Floor Gabriels, Jan A. P. Geurts, et al. "The Implantation of Bioactive Glass Granules Can Contribute the Load-Bearing Capacity of Bones Weakened by Large Cortical Defects." Materials 12, no. 21 (2019): 3481. http://dx.doi.org/10.3390/ma12213481.

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Bioactive glass (BAG) granules (S53P4) have shown good clinical results in one-stage treatment of osteomyelitis. During this treatment, a cortical window is created, and infected bone is debrided, which results in large defects that affect the mechanical properties of the bone. This study aimed to evaluate the role of BAG granules in load-bearing bone defect grafting. First, the influence of the geometry of the cortical window on the bone bending stiffness and estimated failure moments was evaluated using micro finite element analysis (µFE). This resulted in significant differences between the

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7

Grassi, Miriam, Marco Mattia Larghi, Davide Brioschi, Marianatonietta Scazzarriello, and Alfonso Manzotti. "A case of chronic ankle osteomyelitis treated with bioactive glass and tibiocalcaneal fusion." Journal of the Foot & Ankle 19, no. 1 (2025): 1–5. https://doi.org/10.30795/jfootankle.2025.v19.1832.

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Limb-salvage surgery in cases of chronic osteomyelitis poses significant challenges for orthopedic surgeons. This case report presents the first documented instance of a successful staged limb-salvage treatment for chronic ankle osteomyelitis, combining tibiocalcaneal fusion with bioactive glass (BAG). Bioactive glass S53P4 is a synthetic, biocompatible, osteoconductive bone substitute known for its bone-bonding capabilities, antibacterial and angiogenesis-promoting properties, which could be suitable for treating bone defects in infections. The subject of this case is a 68-year-old male with

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8

Peltola, Matti, Kalle Aitasalo, Teemu Tirri, Jami Rekola, and A. Puntala. "Long-Term Tissue Reactions of Three Biomaterials in Craniofacial Surgery." Key Engineering Materials 361-363 (November 2007): 1343–46. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.1343.

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Successful craniofacial reconstruction needs both a well-known and a reliable reconstruction material. However, there is often a lack of long-term knowledge of the tissue reactions and healing process in the human body. In this study, frontal sinus obliterations with bovine bone natural hydroxyapatite derivative (BHA), synthetic bioactive glass S53P4 (BAG) and hydroxyapatite cement (HAC) were investigated with clinical, histologic, scanning electron microscopic (SEM) and energy dispersive x-ray analysis (EDXA) 27, 12 and 3 years postoperatively. The aim was to determine the long-term clinical

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9

Bortolin, Monica, Elena De Vecchi, Carlo Luca Romanò, Marco Toscano, Roberto Mattina, and Lorenzo Drago. "Antibiofilm agents against MDR bacterial strains: is bioactive glass BAG-S53P4 also effective?" Journal of Antimicrobial Chemotherapy 71, no. 1 (2015): 123–27. http://dx.doi.org/10.1093/jac/dkv327.

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10

Alhotan, Abdulaziz, Zbigniew Raszewski, Katarzyna Chojnacka, et al. "Evaluating the Translucency, Surface Roughness, and Cytotoxicity of a PMMA Acrylic Denture Base Reinforced with Bioactive Glasses." Journal of Functional Biomaterials 15, no. 1 (2023): 16. http://dx.doi.org/10.3390/jfb15010016.

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The colonisation of the surface of removable acrylic dentures by various types of microorganisms can lead to the development of various diseases. Therefore, the creation of a bioactive material is highly desirable. This study aimed to develop a denture base material designed to release bioactive ions into the oral environment during use. Four types of bioactive glasses (BAG)—S53P4, Biomin F, 45S5, and Biomin C—were incorporated into the PMMA acrylic resin, with each type constituting 20 wt.% (10 wt.% non-silanised and 10% silanised) of the mixture, while PMMA acrylic resin served as the contro

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