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Relevant bibliographies by topics / Benefits of extended-release tablet

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Academic literature on the topic 'Benefits of extended-release tablet'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Benefits of extended-release tablet"

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Chandra, Prakash Sunuwar* Meenakshi Kandwal Shivanand Patil. "A Review on Formulation and Evaluation of Mirabegron Extended-Release Tablets." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4859–65. https://doi.org/10.5281/zenodo.15547921.

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A type of modified-release dosage form known as an extended-release (ER) tablet is designed to release the active pharmaceutical ingredient (API) gradually over a long period of time. The human body metabolizes and excretes drugs at different rates. Fast drug absorption may result in peak plasma concentrations that could be harmful, whereas fast clearance in conventional formulations causes subtherapeutic levels that necessitate frequent dose. Extended-release formulations get around these issues and ensure a long-lasting therapeutic effect by modifying the kinetics of medicine release. This s

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Chandan, Singh* Rita Saini Shivanand Patil. "A Review of Bilayer Tablet Technology Immediate and Extended-Release Drug Delivery." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4491–503. https://doi.org/10.5281/zenodo.15534239.

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Compared to monotherapy (traditional dosage forms), combination therapy is more common and has several benefits.  The best and most recent example of mixed dose formulation is bilayer tablet technology. The pharmaceutical industry has seen a rise in single-dose formulation that combines 2 or 3 molecules within the tablets. By lowering the number of dosages and increasing the bioavailability of dosage forms, it is well known for encouraging patient convenience and compliance.  Innovative variations of traditional oral drug delivery technologies are bilayer or multilayer tablets. The o

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Lin, Wen, Yinke Li, Qiongzhi Shi, et al. "Preparation and evaluation of bilayer-core osmotic pump tablets contained topiramate." PLOS ONE 17, no. 2 (2022): e0264457. http://dx.doi.org/10.1371/journal.pone.0264457.

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Topiramate (TPM) was an antiepileptic agent commonly used in clinical. Studies showed that an oral preparation of TPM with extended-release manner could bring some benefits for epileptics. In this paper, controlled release push-pull osmotic pump (PPOP) tablets of sparingly water-soluble TPM were successfully prepared. This bi-layer tablet core mainly consisted of sodium chloride as osmotic promoting agent and polyethylene oxide as suspending and pushing agents. The influences of osmotic agents, pushing agents and the compositions of coating membrane on TPM release profiles were evaluated. An o

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Galankar, Vipulata P., Ganesh D. Basarkar, Chandrashekhar D. Upasani, and Sunil V. Amrutkar. "Indomethacin-Loaded Nanosponges for Oral Delivery: Formulation Strategy, Optimization, and In-vitro Evaluation." International Journal of Drug Delivery Technology 15, no. 02 (2025): 01–07. https://doi.org/10.25258/ijddt.15.2.15.

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Chronic illnesses like arthritis cause pain and inflammation, requiring extended oral analgesic therapy. To reduce adverse reactions, active pharmaceutical ingredients are administered through sustained-release dosage forms. However, methods like matrix tablets, osmotic systems, and ion exchange resins have limitations. Nanotechnological approaches like nanosponges improve precision and accuracy in medication release manufacturing. Encapsulated formulations offer benefits like reduced side effects, varied dose options, non-irritating properties, and aesthetic appeal. Nanosponges are used in fo

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NIZAMI, FARIDA, and YOGENDRA MALVIYA. "RECENT ADVANCEMENT AND CHALLENGES IN BILAYER TABLET TECHNOLOGY: AN OVERVIEW." Current Research in Pharmaceutical Sciences 11, no. 4 (2022): 91–97. http://dx.doi.org/10.24092/crps.2021.110401.

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Bilayer tablets were developed recently for the effective production of controlled release formulations in various quality levels to give a method of successful drug delivery. Over the last three decades, as the cost and complexity of developing novel pharmacological entities have increased and as the therapeutic benefits of controlled drug administration have been recognized, considerable attention has been focused on developing sustained or controlled release drug delivery systems. It is utilized to produce a variety of antihypertensive formulations. Bilayer tablets allow for the predetermin

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Jayashree, Bhamre* Shraddha Bhavsar Dr. Gokul Talele Bhushan Shewale. "A Systematic Review on Sustained Release Matrix Tablet." International Journal of Pharmaceutical Sciences 2, no. 8 (2024): 2555–64. https://doi.org/10.5281/zenodo.13212215.

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The abstract of the document provides an overview of sustained release drug delivery systems. It emphasizes the goal of delivering therapeutic levels of drugs to specific body sites over extended periods. The document discusses the increasing interest in sustained release systems due to high costs of developing new drugs, patent expirations, discovery of new polymers, and improvements in therapeutic efficiency and safety. Various types of matrix tablets, such as hydrophilic, fat-wax, plastic, biodegradable, and mineral matrices, are classified based on their properties and methods of drug rele

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Khobragade, Deepak S., K. Vighneshwar, and Mrunali S. Potbhare. "Development and Evaluation of Novel Multi-unit Pellet System Formulation of Metoprolol Succinate for Extended Release." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 03 (2022): 1219–27. http://dx.doi.org/10.25258/ijddt.12.3.49.

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Metaprolol succinate is a highly water-soluble drug with extensive first-pass metabolism. It needs to be administered about 3-4 times a day for optimum therapeutic effect. Conventional extended-release formulations are available but have their own disadvantages. The study was to designed formulate and evaluate the prolonged-release compressed multiple-unit pellet system of Metoprolol succinate. MUPS are novel formulations with benefits of both single and multi unit dosage forms and can provide extended drug delivery release profile and increase the efficiency profile of the drug. Metaprolol su

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P, Pavazhaviji, and Rajalakshmi A. N. "FIXED-DOSE COMBINATION DRUGS AS TABLET IN TABLET: A REVIEW." International journal of multidisciplinary advanced scientific research and innovation 1, no. 9 (2021): 169–77. http://dx.doi.org/10.53633/ijmasri.2021.1.9.02.

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The Pharmaceutical industry has become more interested in developing fixed-dose combinations (FDCs) in recent years. FDCs have been used successfully in a variety of clinical areas, including diabetes, HIV/AIDS,and cardiovascular diseases etc. FDCs are intended to extend the product life cycle and enhance patient compliance by decreasing cost. Active Pharmaceutical ingredients are chosen for FDC development based on variety of purposes such as Pharmacokinetic profile, drug-drug interactions, mechanism of action, and manufacturability for successful development. Tablet in tablet technology has

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Sadhu, Venkateswara Rao, Priyanka Bopparaju, and Padmalatha Kantamneni. "Bilayer tablet technology: A novel approach." GSC Biological and Pharmaceutical Sciences 7, no. 2 (2019): 022–28. https://doi.org/10.5281/zenodo.4286145.

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Bilayer tablet is new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Controlled release dosage forms have been extensively used to improve therapy with several important drugs. Use of bilayer tablet is a very different aspect for anti-inflammatory and analgesic. Bilayer tablet is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one Layer is immediate release as initial dose and second lay

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Yadav, Vimal Kumar. "Matrix tablets: benefits, drawbacks and hopes for the future." International journal of therapeutic innovation 1, no. 3 (2023): 75–78. http://dx.doi.org/10.55522/ijti.v1i3.0018.

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The adaptability of matrix tablets, a common drug delivery technology, in regulated and sustained release has drawn a lot of attention in pharmaceutical research and development. The different facets of matrix tablets are examined in this abstract, along with their formulations, benefits, drawbacks, and potential applications. We talked about matrix tablet formulations, benefits, drawbacks, and potential future developments in this review study.

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Dissertations / Theses on the topic "Benefits of extended-release tablet"

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TILLOTSON, JOHN KING. "DEVELOPMENT AND EVALUATION OF EXTENDED-RELEASE BUMETANIDE TABLETS." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1085067185.

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Draganoiu, Elena Simona. "Evaluation Of Kollidon® SR for Ph-Independent Extended Release Matrix Systems." University of Cincinnati / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1054756192.

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Peres, Carolina [UNESP]. "Planejamento de estudo clínico para a avaliação da biodisponibilidade comparativa de nova formulação de liberação prolongada de benzonidazol." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/151961.

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Submitted by Carolina Peres null (carol_peres88@hotmail.com) on 2017-10-20T13:48:07Z No. of bitstreams: 1 Dissertação completa mestrado.pdf: 3043086 bytes, checksum: 409a3054d7b6e44ea30ba5eca7aac1bf (MD5)<br>Approved for entry into archive by Luiz Galeffi (luizgaleffi@gmail.com) on 2017-10-23T19:13:46Z (GMT) No. of bitstreams: 1 peres_c_me_bot.pdf: 3043086 bytes, checksum: 409a3054d7b6e44ea30ba5eca7aac1bf (MD5)<br>Made available in DSpace on 2017-10-23T19:13:46Z (GMT). No. of bitstreams: 1 peres_c_me_bot.pdf: 3043086 bytes, checksum: 409a3054d7b6e44ea30ba5eca7aac1bf (MD5) Previous issue

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Peres, Carolina. "Planejamento de estudo clínico para a avaliação da biodisponibilidade comparativa de nova formulação de liberação prolongada de benzonidazol." Botucatu, 2017. http://hdl.handle.net/11449/151961.

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Orientador: Rosângela Gonçalves Peccinini<br>Resumo: A doença de Chagas é uma enfermidade que afeta milhões de pessoas no mundo, principalmente em países em desenvolvimento. No Brasil, o único fármaco disponível para tratamento desta doença é o benzonidazol (BNZ). Atualmente o regime posológico para adultos consiste na administração deste fármaco na forma de comprimidos de liberação imediata de 100 mg em duas ou três tomadas diárias, durante 60 dias. Apesar da elevada eficácia desse fármaco na fase aguda da doença (aproximadamente 70%), os eventos adversos são frequentes e muitas vezes causam

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Meneghini, Leonardo Zanchetti. "Desenvolvimento e validação de metodologia analítica para bromidrato de darifenacina comprimido." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/96032.

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O objetivo deste trabalho foi o desenvolvimento e validação de métodos analíticos para determinação do bromidrato de darifenacina (DF) em comprimidos de liberação modificada. Na fase de identificação, a matéria-prima do fármaco (substância química de referência) foi analisada e caracterizada utilizando-se de medidas físicas (ponto de fusão, polarimetria, solubilidade), espectroscopia (infravermelho, ultravioleta-visível, massas) e técnicas cromatográficas (cromatografia a líquido de alta eficiência, cromatografia em camada delgada). Nos estágios posteriores, os experimentos para quantificação

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Li, Shu-Hui, and 李淑惠. "Preparation and Evaluation of Nicardipine HCl Matrix Tablet for Extended Release." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/53508166659912483998.

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碩士<br>高雄醫學大學<br>藥學研究所碩士班<br>92<br>Controlled release may be defined as a technique by which drug are made available to a target at a fixed rate and duration to produce a desirable therapeutic effect. The purpose of the study was to prepare nicardipine matrix for extended release. HPMC was selected as carrier to prepare nicardipine tablets and Sodium alginate and Avicel® were used to confer the release of drug. The response surface methodology (RSM) and multiple responses optimization polynomial equation were used to obtain optimal nicardipine matrix for extended release. First of all the relea

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Books on the topic "Benefits of extended-release tablet"

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Pham, Thien C., Courtney Kominek, Abigail Brooks, and Jeffrey Fudin. Opioid Pharmacotherapies for Chronic Pain (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190265366.003.0014.

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Chronic pain management employing opioids is divided into subtopics, including: risk–benefit balance; a review of the mode of action of opioid analgesics (Chap. 8); the suitability of synthetic opioids for neuropathic pain; endocrinopathy proceeding from opioid use; the use of the morphine-equivalent daily dose as a conversion tool for managing multiple opioids; the place of extended-release and long-acting opioids; current technology in abuse deterrence; and an overview of the challenges entailed in prescribing. This last section details the complex components of a decision to prescribe opioi

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Book chapters on the topic "Benefits of extended-release tablet"

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Pazhayattil, Ajay Babu, and Sanjay Sharma. "Case Study: Dissolution OOT Observed for an Extended-Release Tablet Formulation." In AAPS Introductions in the Pharmaceutical Sciences. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-86504-6_6.

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Sowmyasree, Golla Venkata. "Tablets." In A Text Book of Pharmaceutics for I Year Diploma in Pharmacy. THINKPLUS PHARMA PUBLICATIONS, 2024. http://dx.doi.org/10.69613/736rs621.

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Tablets are the most widely used solid dosage form in pharmaceutical practice, offering advantages such as precise dosing, stability, and patient convenience. This section explores the various types of tablets, including immediate-release, modified-release, and orally disintegrating tablets, each designed to meet specific therapeutic needs. The composition of tablets, including active ingredients and excipients such as diluents, binders, disintegrants, and lubricants, is discussed in detail. Tablet manufacturing processes, from wet granulation and dry granulation to direct compression, are exa

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Navabhatra, A., and B. Yingngam. "Biocompatible Tablet Film Coatings for Active Pharmaceutical Ingredients." In Medical Applications for Biocompatible Surfaces and Coatings. Royal Society of Chemistry, 2024. http://dx.doi.org/10.1039/9781837675555-00076.

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In the pharmaceutical industry, the process of coating tablets with active pharmaceutical ingredients (APIs) poses significant challenges related to biocompatibility and drug efficacy. Traditional coatings often have limitations in terms of their compatibility with the human body, which can lead to decreased bioavailability and adverse reactions. This chapter aims to address these challenges by focusing on the development of biocompatible tablet film coatings that are specifically designed to deliver APIs while also ensuring safety and enhancing patient compliance. The chapter explores the for

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Sunitha, Ramineni, Praveen Sivadasu, and Raghavendra Kumar Gund. "Statistical Optimization and Evaluation of Extended Release Tablets for Divalproex Sodium." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00549.

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The purpose of current experimental research is to optimize the quantities of macromolecules such as EudragitL/100-55, HPMC-K-100M for the development of divalproex sodium extended release tablets. Divalproexsodium, an anticonvulsant or epileptic agent. It was used in the effective management of bipolar disorders, Mania, seizures, convulsions, tremors/epilepsy. Divalproex sodium ER tablets were formulated with the help of EudragitL/100-55 and HPMC-K-100M in variable composition and variable amounts as per 32 factorial design technique. They were prepared by direct compression technique. Quanti

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G, Suchita, Dr Smita T, Sahil M, Kalpesh M, and Sayali N. "MATRIX CONTROLLED DRUG RELEASE DRUGDELIVERY." In Futuristic Trends in Pharmacy & Nursing Volume 2 Book 25. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2023. http://dx.doi.org/10.58532/v2bs25p3ch3.

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Formulations that are able to control the release of drug have become an integral part of the pharmaceutical industry. In particular oral drug delivery has been the focus of pharmaceutical research for many years. This type of drug delivery has been at the centre of research due to its many benefits over conventional dosage. The focus of this review is on matrix tablets due to their widely use and simplicity of the formulation. This includes the discussion of various types of matrix tablets and factors affecting the drug release from these formulations. The development of oral controlled relea

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Zeiss, Daniel Horst, and Linda Amundstuen. "Information Regarding Modification of Oral Solid Medicines in Written Drug Information: Potential Consequences for Patient Safety." In Medication Safety in Municipal Health and Care Services. Cappelen Damm Akademisk/NOASP, 2022. http://dx.doi.org/10.23865/noasp.172.ch5.

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Oral solid medicines (oral solid dosage forms, OSDFs) are among the most used medications, and have various pharmaceutical designs ranging from relatively simple uncoated tablets with immediate-release properties, to advanced modified-release preparations slowly releasing the active ingredient. Taking medicines correctly is essential to preserve intended effects and avoid adverse effects. Still, modification of OSDFs is a common practice among patients and health care personnel, due to for example, swallowing difficulties. Modifications such as crushing tablets and opening capsules should only

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Kelly, Alan, Patrick Fox, and Tim Cogan. "Fermented Milks." In From Farm to Table. Oxford University PressNew York, NY, 2024. https://doi.org/10.1093/9780197581025.003.0007.

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Abstract This chapter introduces fermented milks, which are some of the oldest and most widespread dairy products, relatively easy to produce, and with an extended shelf-life compared to raw milk. It describes the production and manufacture of several of the important fermented milks, including yoghurt, cultured buttermilk, sour cream, kefir, and koumiss, which is made from mare’s milk. The chapter also describes Scandinavian, Middle Eastern, Indian fermented milks and the Japanese product, Yakult. Finally it considers the role of probiotic bacteria and the range of health benefits attributed

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Banacloche, Santacruz, Ana Rosa Gamarra, Natàlia Caldés, and Yolanda Lechón. "Extended input-output tables to analyze the benefits of renewable energy deployment." In Handbook on the Economics of Renewable Energy. Edward Elgar Publishing, 2023. http://dx.doi.org/10.4337/9781800379022.00011.

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Stoesz, David. "The Welfare State on Autopilot." In Building Better Social Programs. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190945572.003.0002.

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The Welfare State emerged during industrialization as a means to ensure the protection of citizens from illness, unemployment, and destitution. Yet, government social program commitments vary across nations, with some less affluent countries performing better than their more affluent counterparts, as demonstrated in league tables. Originating in medicine, the evidence-based policy movement has extended to the social arena, showing how public investments can produce public benefit. However, reviewing extant programs with regard to efficacy and efficiency has lagged.

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M N, Madhavi, Pankaj M. Pimpalshende, Satish B. Kosalge, Shubhangi M. Kaurase, and Rajashree V. Lode. "A NOVEL APPROACH TO DRUG DELIVERY SYSTEMS: MICROSPONGES." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 16. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bkpn16p2ch2.

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To maximize therapeutic efficacy and cost-effectiveness, innovative drug delivery technology has developed intensely competitive and is growing quickly. Microsponges are one of these cutting-edge developing techniques for precise, controlled, and target-specific medication administration. Microsponges are microscopic polymeric particles with porous surfaces resembling sponges, and pore ranges in size from 5 to 300 microns. The microsponge system can be made into gel, ointment, creams, liquids, or powders with good efficiency. More recently, it has been made into tablets and capsules for oral d

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Conference papers on the topic "Benefits of extended-release tablet"

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Payares, Lily Margareth, Virginia Paredes Méndez, Margareth Dugarte, Juan Carlos Rincón Montenegro, and Lizeth Gutiérrez Púa. "Use of the Microalgae Chlorella Sp. to Biofunctionalized Magnesium Surfaces in Order to Decrease the Rate of Corrosion and Promote the Bone Remodeling Process." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-18514.

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Extended Abstract Frequently, the human body is susceptible to injuries such as the fracture of one or more of its bones, so it is necessary to use implants or some fixation element to keep the fragments of the fracture together, allowing an orderly repair that facilitates healing or compensates the lack or loss of bone tissue. Temporary orthopedic implants have been used clinically to repair broken or fractured bones during the healing process. The most used are plates, screws, nails, wires, and intramedullary nails. It is usually necessary to perform operations to open the injury site, join

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Grundy, John, Anthony Blackburn, Ed Parsley, Yong Tang, Christopher King, and John Adams. "Clinical pharmacokinetic (PK) performance of a ralinepag extended-release (XR) tablet." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3037.

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Sunzel, Eva-Maria, Laura Rabinovich-Guilatt, Malini Iyengar, et al. "A Bioequivalence Comparison at Steady State between the Newly Developed Once-Daily Extended Release Tablet Formulation and the Approved Twice-Daily Tablet Formulation of Deutetrabenazine (P2-11.015)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000202209.

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Mohamed, M.-EF, J. Zeng, I.-H. Song, and AA Othman. "THU0177 ABT-494 pharmacokinetics following administration of the once-daily extended-release tablet formulation being utilized in the ongoing rheumatoid arthritis phase 3 trials." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.3224.

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Siemieniec, Ralf, Cesar Braz, Simone Mazzer, and Gerhard Nöbauer. "New Power MOSFET and their use in Intermediate Bus Converters." In 16th International Seminar On Power Semiconductors. Czech Technical University in Prague, 2023. http://dx.doi.org/10.14311/isps.2023.006.

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This work investigates the performance of our latest trench power MOSFET technology in an Intermediate Bus Converter as widely used in telecom and data centre power supplies. Based on the advantages of a revolutionary new cell design combined with the benefits of an advanced manufacturing technology, the new devices combine the benefits of low conduction losses and superior switching performances with an extended SOA and good ruggedness. These features make the devices an ideal fit especially for high switching frequency applications. The recent release of 80 V and 100 V devices offers the pot

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Korakianitis, T., R. Dyer, and N. Subramanian. "Pre-Integrated Non-Equilibrium Combustion-Response Mapping for Gas-Turbine Emissions." In ASME Turbo Expo 2001: Power for Land, Sea, and Air. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/2001-gt-0386.

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In gas-turbine combustion the gas-dynamic and chemical-energy-release mechanisms have comparable time scales, so that equilibrium chemistry is inadequate for predicting species formation (emissions). In current practice either equilibrium chemical reactions are coupled with experimentally derived empirical equations, or time-consuming computations are used. Coupling non-equilibrium chemistry, fluid-dynamic, and initial- and boundary-condition equations results in large sets of numerically stiff equations; and their time integration demands enormous computational resources. The response modelin

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Sunzel, Eva-Maria, Giulia Ghibellini, Malini Iyengar, et al. "Assessment of Dose Proportionality of Three Dose Strengths (6 mg, 12 mg and 24 mg) over the Clinical Dose Range (6–48 mg) of the Newly Developed Once-Daily Extended Release Tablet Formulation of Deutetrabenazine (P2-11.016)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000202218.

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Cheung, Yushing, Jae H. Chung, and Ketula Patel. "Semi-Autonomous Collaborative Control of Multi-Robotic Systems for Multi-Task Multi-Target Pairing." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64699.

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In many applications, it is required that heterogeneous multi-robots are grouped to work on multi-targets simultaneously. Therefore, this paper proposes a control method for a single-master multi-slave (SMMS) teleoperator to cooperatively control a team of mobile robots for a multi-target mission. The major components of the proposed control method are the compensation for contact forces, modified potential field based leader-follower formation, and robot-task-target pairing method. The robot-task-target paring method is derived from the proven auction algorithm for a single target and is exte

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Chapman, Neil, Charles McCombie, and Edwoud Verhoef. "Implications of Co-Existing National and Multinational Geological Repository Development Programmes in Europe." In ASME 2011 14th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2011. http://dx.doi.org/10.1115/icem2011-59118.

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The aim of this paper is to identify interactions between national and multi-national geological repository programmes that are potentially either beneficial or problematic, so as to avoid any unintended negative impacts on national or multinational programmes and to maximise mutual benefits wherever possible. Regional, multi-national cooperation on geological disposal is a topical issue at present at the IAEA and also in the EU, which has produced a new proposed Directive that explicitly allows agreements on sharing. Two extended tables in the paper identify and comment briefly on historic an

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James, Peter M., Dennis G. Hooton, Lorna A. Higham, Colin J. Madew, John K. Sharples, and Chris T. Watson. "Continuing Development of a Simplified Method to Account for the Interaction of Primary and Secondary Stresses." In ASME 2008 Pressure Vessels and Piping Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/pvp2008-61040.

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The R6 defect assessment procedure, used commonly in the UK nuclear industry to assess the significance of defects in structures, uses the Failure Assessment Diagram to evaluate limiting parameters whilst accounting for the effects of plasticity. The interaction of primary and secondary stress is accounted for within R6 through the use of the ρ, or an equivalent V, term. ‘Look-up’ tables are provided in order to evaluate parameters required to derive the ρ or V terms. In some circumstances, the current methodology has been shown to be excessively conservative and the use of the ‘look-up’ table

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Reports on the topic "Benefits of extended-release tablet"

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Lichter, Amnon, Joseph L. Smilanick, Dennis A. Margosan, and Susan Lurie. Ethanol for postharvest decay control of table grapes: application and mode of action. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7587217.bard.

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Original objectives: Dipping of table grapes in ethanol was determined to be an effective measure to control postharvest gray mold infection caused by Botrytis cinerea. Our objectives were to study the effects of ethanol on B.cinerea and table grapes and to conduct research that will facilitate the implementation of this treatment. Background: Botrytis cinerea is known as the major pathogen of table grapes in cold storage. To date, the only commercial technology to control it relied on sulfur dioxide (SO₂) implemented by either fumigation of storage facilities or from slow release generator pa

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