Academic literature on the topic 'Benzodiazepine'

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Journal articles on the topic "Benzodiazepine"

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Nsira, Asma, Ahlem Karoui, Rafik Gharbi, and Moncef Msaddek. "Chemoselectivity of the 1,3-Dipolar Cycloaddition of Some Diazoalkanes with 1,5-Benzodiazepine Derivatives." Journal of Chemical Research 36, no. 3 (2012): 152–56. http://dx.doi.org/10.3184/174751912x13300109535030.

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Benzodiazepines are pharmaceutically important synthetic materials. Reaction of the 4-(2-hydroxyphenyl)-1,5-benzodiazepin-2-one with 2-diazopropane (DAP) gave a mixture of the 2-isopropylether of 4-(2-hydroxyphenyl)-3H-1,5-benzodiazepine and 1-isopropyl-4-(2-hydroxyphenyl)-3H-1,5-benzodiazepin-2-one. Whilst diphenyldiazomethane (DPDM) gave 1-benzhydryl-4-(2-hydroxyphenyl)-3H-1,5-benzodiazepin-2-one. Reaction of the corresponding thione with DAP led to the 2-isopropylthioether of 4-(2-hydroxyphenyl)-3H-1,5-benzodiazepine and 1-isopropyl-4-(2-hydroxyphenyl)-1,5-benzodiazepine-2-thione while the
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Rotaru, Luciana Teodora, Paul Nedelea, Renata-Maria Varut, et al. "Determining the Influence of Alcohol on the Pharmacological Effect of Benzodiazepines by Molecular Docking Tehnique." Revista de Chimie 70, no. 3 (2019): 814–19. http://dx.doi.org/10.37358/rc.19.3.7013.

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Benzodiazepines represents a large category of medications that were originally developed to treat anxiety disorders or issues with anxiety, seizures, and issues with sleeping. The most common drugs abused along with benzodiazepines are other benzodiazepines, prescription pain medications and alcohol. Alcohol and benzodiazepine have a synergistic depressant effect on the central nervous system. Combining alcohol with benzodiazepines can be dangerous practice even if it is engaged in only occasionally. In the present study, using molecular docking technique we followed the binding energy of ben
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Muzaale, Abimereki D., Matthew Daubresse, Sunjae Bae, et al. "Benzodiazepines, Codispensed Opioids, and Mortality among Patients Initiating Long-Term In-Center Hemodialysis." Clinical Journal of the American Society of Nephrology 15, no. 6 (2020): 794–804. http://dx.doi.org/10.2215/cjn.13341019.

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Background and objectivesMortality from benzodiazepine/opioid interactions is a growing concern in light of the opioid epidemic. Patients on hemodialysis suffer from a high burden of physical/psychiatric conditions, which are treated with benzodiazepines, and they are three times more likely to be prescribed opioids than the general population. Therefore, we studied mortality risk associated with short- and long-acting benzodiazepines and their interaction with opioids among adults initiating hemodialysis.Design, setting, participants, & measurementsThe cohort of 69,368 adults initiating h
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Lyukshenko, Natalya I., Roman G. Nikitin, and Yury V. Morozhenko. "New technology to obtain 1-methyl-5-pnenyl-7-chloro- 1,3-dihydro-2H-[1,4]-benzodiazepine-2-one." Butlerov Communications 60, no. 10 (2019): 24–31. http://dx.doi.org/10.37952/roi-jbc-01/19-60-10-24.

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At present, benzodiazepine derivatives being used widely, they continue to occupy a leading position among the drugs of the anxiolytic group. Most anxiolytics of the benzodiazepine structure are derivatives of 1,4-benzodiazepine. The basis of the chemical benzodiazepine structure consists of a benzene ring connected to a seven-membered heterocyclic ring containing two nitrogen atoms (diazepine) at positions 1 and 4. All the benzodiazepine derivatives used in the clinic also have a second benzene ring attached to carbon. The presence of a halogen or a nitro group is essential to display its act
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Williams, Hugh, Doug Handyside, Kirsty Bashford, and Adenekan Oyefeso. "Service response to benzodiazepine use in opiate addicts: a national postal survey." Irish Journal of Psychological Medicine 22, no. 1 (2005): 15–18. http://dx.doi.org/10.1017/s0790966700008739.

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AbstractObjectives: The study reports on benzodiazepine use among opiate dependent patients attending National Health Service community prescribing services and examines current practice in the clinical management of benzodiazepine dependence.Method: A postal questionnaire survey of 174 NHS substance misuse services in England and Wales.Results: A 71% response rate was achieved. Services estimated the prevalence of benzodiazepine use to be 40% and the prevalence of benzodiazepine dependence to be less than 25% among opiate dependent patients in treatment. Illicit supplies (street) and general
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Ritvo, Alexis D., D. E. Foster, Christy Huff, A. J. Reid Finlayson, Bernard Silvernail, and Peter R. Martin. "Long-term consequences of benzodiazepine-induced neurological dysfunction: A survey." PLOS ONE 18, no. 6 (2023): e0285584. http://dx.doi.org/10.1371/journal.pone.0285584.

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Background Acute benzodiazepine withdrawal has been described, but literature regarding the benzodiazepine-induced neurological injury that may result in enduring symptoms and life consequences is scant. Objective We conducted an internet survey of current and former benzodiazepine users and asked about their symptoms and adverse life events attributed to benzodiazepine use. Methods This is a secondary analysis of the largest survey ever conducted with 1,207 benzodiazepine users from benzodiazepine support groups and health/wellness sites who completed the survey. Respondents included those st
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Smithers, Alex, Laura Miller, Melanie MacInnis, and Selene Etches. "Benzodiazepine Use Disorder Observed and Diagnosed in a Tertiary Care Pediatric Specialty Clinic: A Descriptive Retrospective Chart Review." BJPsych Open 10, S1 (2024): S64—S65. http://dx.doi.org/10.1192/bjo.2024.211.

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AimsObjectives: In youth and young adults, it is common to encounter non-medical use of benzodiazepines, defined as use without a prescription or use for reasons other than that for which the medication is intended. Benzodiazepine use disorder remains understudied and overlooked, especially in youth and young adults. The primary objective of our study was to highlight the proportion of youth and young adults with aberrant use of benzodiazepines and diagnosed with benzodiazepine use disorder in a single centre. The secondary objective was to determine factors associated with aberrant benzodiaze
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van der Sluiszen, Nick, Annemiek Vermeeren, Stefan Jongen, Frederick Vinckenbosch, and Johannes Ramaekers. "Influence of Long-Term Benzodiazepine use on Neurocognitive Skills Related to Driving Performance in Patient Populations: A Review." Pharmacopsychiatry 50, no. 05 (2017): 189–96. http://dx.doi.org/10.1055/s-0043-112755.

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AbstractAcute benzodiazepine intoxication produces severe impairment of neurocognitive skills related to driving. It is less clear whether such impairments also occur in patients who use benzodiazepines chronically. The current review evaluated neurocognitive skills of long-term benzodiazepine users and addressed 2 major questions: do long-term users develop tolerance for the impairing effects of benzodiazepines on neurocognitive performance, and if so, does tolerance warrant a change in driver fitness classification systems that currently deem users of benzodiazepines unfit to drive? Neurocog
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Kim, Yoseop, та Sung-Gon Kim. "Stereoselective [4+3]-Cycloaddition of 2-Amino-β-Nitrostyrenes with Azaoxyallyl Cations to Access Functionalized 1,4-Benzodiazepin-3-Ones". Molecules 29, № 6 (2024): 1221. http://dx.doi.org/10.3390/molecules29061221.

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The 1,4-benzodiazepine structural framework is a fascinating element commonly found in biologically active and pharmaceutically relevant compounds. A highly efficient method for synthesizing 1,4-benzodiazepin-3-ones is described, involving a [4+3]-cycloaddition reaction between 2-amino-β-nitrostyrenes and α-bromohydroxamate, with Cs2CO3 used as a base. This process yielded the desired 1,4-benzodiazepines in good yields. Furthermore, an organocatalytic asymmetric [4+3]-cycloaddition was successfully accomplished using a bifunctional squaramide-based catalyst. This approach enabled the enantiose
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Grønbæk, Lisbet, Hugh Watson, Hendrik Vilstrup, and Peter Jepsen. "Benzodiazepines and risk for hepatic encephalopathy in patients with cirrhosis and ascites." United European Gastroenterology Journal 6, no. 3 (2017): 407–12. http://dx.doi.org/10.1177/2050640617727179.

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Background There is limited evidence to support the belief that benzodiazepines increase cirrhosis patients’ risk of hepatic encephalopathy (HE). Objective We aimed to examine the association between benzodiazepine use and HE development in cirrhosis patients. Methods We used data on 865 cirrhosis patients with ascites from three trials to study the effect of benzodiazepine use on development of first-time HE. For each patient, we classified periods of benzodiazepine use by the number of days since initiation. We used Cox regression to compare the risk of HE in current benzodiazepine users vs.
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Dissertations / Theses on the topic "Benzodiazepine"

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Rizzo, Michael L. "The Prescribing Knowledge, Attitudes, and Practices among Nurse Practitioners in Maine towards Benzodiazepines." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/RizzoML2004.pdf.

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Kavvadias, Dominique. "Liganden des Benzodiazepin-Rezeptors Studien über Benzodiazepine in pflanzlichen Geweben sowie über Hispidulin /." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969716087.

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Fluck, Emma Jane. "Benzodiazepine modulation of human memory." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300711.

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Elliot, Elizabeth. "Benzodiazepine tolerance and withdrawal quantified using radiotelemetry /." Title page, abstract and contents only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phe461.pdf.

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Diorio, Diane Lynn. "Peripheral benzodiazepine binding sites in psychiatric disorders." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55676.

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Bilbe, Graeme. "Molecular studies on the gaba-benzodiazepine receptor." Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37639.

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SEROR, PAULE-MICHELE. "Les antagonistes des benzodiazepines." Lyon 1, 1989. http://www.theses.fr/1989LYO1M257.

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NICOLAI, LAURENT. "Effets amnesiants des benzodiazepines." Strasbourg 1, 1992. http://www.theses.fr/1992STR15003.

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Guenoux, Charles-Albert. "Benzodiazepines : aspects pharmacologiques actuels." Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20952.

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Barbut, Frédéric. "Les récepteurs des benzodiazépines." Paris 5, 1988. http://www.theses.fr/1988PA05P169.

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Books on the topic "Benzodiazepine"

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Cosmo, Hallström, ed. Benzodiazepine dependence. Oxford University Press, 1993.

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Hippius, H., R. R. Engel, and G. Laakmann, eds. Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9.

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Lacey, Ron. That's life! survey on tranquillisers. British Broadcasting Corporation in association with MIND, 1985.

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F, Squires Richard, ed. GABA and benzodiazepine receptors. CRC Press, 1988.

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1944-, Hindmarch I., ed. Benzodiazepines: Current concepts : biological, clinical, and social perspectives. Wiley, 1990.

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Network, Drug Abuse Warning, National Institute on Drug Abuse. Division of Epidemiology and Statistical Analysis., and CSR Incorporated, eds. A Decade of DAWN: Benzodiazepine-related cases, 1976-1985 : topical data from the Drug Abuse Warning Network. U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Division of Epidemiology and Statistical Analysis, 1988.

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Cormack, Margaret A., Michael E. Dewey, and R. Glynn Owens. Reducing Benzodiazepine Consumption. Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4612-3672-6.

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E, Giesen-Crouse, ed. Peripheral benzodiazepine receptors. Academic Press, 1993.

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Martin, Sarter, Nutt David J. 1951-, and Lister Richard G, eds. Benzodiazepine receptor inverse agonists. Wiley-Liss, 1995.

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Ivan, Izquierdo, and Medina Jorge, eds. Naturally occurring benzodiazepines: Structure, distribution, and function. Ellis Horwood, 1993.

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Book chapters on the topic "Benzodiazepine"

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Müller, W. E. "Die Wirkung der Benzodiazepine auf neuronaler Ebene." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_1.

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Rüther, E. "Benzodiazepine zur Behandlung von Schlafstörungen." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_10.

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Martinius, J. "Benzodiazepine als Sedativa und Antikonvulsiva in der Kinder— und Jugendpsychiatrie." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_11.

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Nissen, G. "Benzodiazepine in der Behandlung von Angstsyndromen in der Kinder— und Jugendpsychiatrie." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_12.

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Berzewski, H. "Risiken und Komplikation bei der Behandlung des alten Menschen mit Benzodiazepinen." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_13.

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Kanowski, S. "Benzodiazepine in der Gerontopsychiatrie." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_14.

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Laakmann, G., D. Blaschke, H. Hippius, and D. Messerer. "Wirksamkeits— und Verträglichkeitsvergleich von Alprazolam gegen Amitriptylin bei der Behandlung von depressiven Patienten in der Praxis des niedergelassenen Allgemein— und Nervenarztes." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_15.

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Pöldinger, W. "Die Bedeutung der Benzodiazepinderivate in der Depressionsbehandlung." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_16.

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Heimann, H. "Zukunftsperspektiven." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_17.

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Gerken, A., F. Holsboer, and O. Benkert. "Untersuchung über den Einfluß von Nordiazepam auf die Plasmakonzentration von Amitriptylin und Nortriptylin." In Benzodiazepine. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70621-9_18.

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Conference papers on the topic "Benzodiazepine"

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Doane, Eric. "Isolated Temazepam Overdose: A Unique Case of an Unresponsive Female." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.106_2023.

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Cases of acute overdose presenting to the emergency department pose a great challenge given that history can sometimes be limited or at times be inaccurate. While naloxone is routinely given in the field to help reduce opiate’s sedating effects, the routine use of flumazenil has not been routinely adopted in cases of benzodiazepine overdose. This is because, unlike naloxone, there are many medications that act on the GABA receptor, and flumazenil is only specific for binding to the benzodiazepine/GABA receptor. This can lead to an unmasking of other medications that may be co-ingested that als
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Castaneda, J. M., T. Wai, L. J. Spece, et al. "Risks of Non-benzodiazepine Benzodiazepine Receptor Agonists Among Patients With Chronic Obstructive Pulmonary Disease." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5967.

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Роман Анатольевич, Калёкин,, Волкова, Алла Андреевна, Павлова, Альбина Захаровна, Орлова, Алевтина Михайловна, and Павлов, Андрей Леонидович. "TOXIC EFFECTS OF BENZODIAZEPINE RECEPTOR AGONISTS." In Теоретические основы и практическое применение инновационных исследований: сборник статей международной научной конференции (Москва, Ноябрь 2022). Crossref, 2022. http://dx.doi.org/10.37539/221111.2022.42.92.006.

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Рассмотрена группа психотропных лекарственных средств - анксиолитиков при использовании в современной медицине с возможностью токсического воздействия на организм человека и вероятностью отравления ими. Описаны лекарственные препараты из агонистов бензодиазепиновых рецепторов применяемых в России как объекты химико-токсикологического и судебно-химического исследования. A group of psychotropic drugs - anxiolytics when used in modern medicine with the possibility of toxic effects on the human body and the likelihood of poisoning by them is considered. Medicinal preparations from benzodiazepine r
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Deng, Fusheng, Jingling Shen, and Xianfeng Wang. "Terahertz spectroscopic study of benzodiazepine sedative hypnotics." In International Symposium on Photoelectronic Detection and Imaging 2011. SPIE, 2011. http://dx.doi.org/10.1117/12.900786.

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Banerjee, Jyotirmoy, Aparna Dixit, P. Sarat Chandra, and Manjari Tripathi. "Targeting Gaba-A Receptors: Looking Beyond Benzodiazepine." In ECON 2023. Thieme Medical and Scientific Publishers Pvt. Ltd., 2023. http://dx.doi.org/10.1055/s-0044-1791456.

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Gayen, S., G. Carbell, N. Kaur, et al. "Phenobarbital Can Reduce Intensive Care Unit Length of Stay in Patients With Alcohol/Benzodiazepine Withdrawal as Compared to Benzodiazepines." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2595.

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Fogliano, Chiara, Bice Avallone, Chiara Maria Motta, and Rosa Carotenuto. "Influence of Benzodiazepine Delorazepam on Xenopus laevis Embryogenesis." In The 7th World Congress on Civil, Structural, and Environmental Engineering. Avestia Publishing, 2022. http://dx.doi.org/10.11159/iceptp22.194.

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Lehfeld, Letícia D'Agostino, and Camila Tavares Valadares da Silva. "Comparative analysis of z-hypnotics and benzodiazepines for insomnia." In III Seven International Medical and Nursing Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/iiicongressmedicalnursing-006.

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The Brazilian population has a 72% incidence of sleep disorders, the main one being insomnia. Furthermore, the use of z-hypnotics increased by 73% among Brazilians from 2019 to 2021. Based on this, this study aims to conduct a bibliographic review on the use of z-hypnotics, such as zolpidem and eszopiclone, and their repercussions compared to benzodiazepines. As a methodology, scientific articles from SciELO, Revista Neurociências, Revista Brasileira de Psiquiatria and Revista Brasileira de Neurologia cataloged in recent years were used. As a result, it was found that the use of benzodiazepine
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Henry, Mark, Danny J. Eckert, Matthias Eikermann, Atul Malhotra, and Nancy L. Chamberlin. "Effects Of The Non-Benzodiazepine Sedative Eszopiclone Vs. The Benzodiazepine Temazepam On Genioglossus Muscle Activity And Ventilatory Responses To CO2 In Rats." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2204.

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Michail, Emmanouil, Ioanna Chouvarda, and Nicos Maglaveras. "Benzodiazepine administration effect on EEG Fractal Dimension: results and causalities." In 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010). IEEE, 2010. http://dx.doi.org/10.1109/iembs.2010.5627851.

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Reports on the topic "Benzodiazepine"

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Marczynski, Thaddeus J. Attention Span, Anxiety and Benzodiazepine Receptors. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada234549.

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Papadopoulos, Vassilios. Peripheral Benzodiazepine Receptor in Human Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada405505.

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Papadopoulas, Vassilios. Peripheral Benzodiazepine Receptor (PBR) in Human Breast Cancer. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada420939.

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Lee, Jenna. Effects of Long-Term Benzodiazepine Use on Cognitive Testing. Iowa State University, 2021. http://dx.doi.org/10.31274/cc-20240624-599.

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Campbell, Tonya, Siyu Men, Gurnoor Brar, et al. Characterizing Prescription Benzodiazepine Use among Community-Dwelling Residents of Ontario, Canada. ODPRN, 2021. http://dx.doi.org/10.31027/odprn.2021.01.

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Das, Salil K. Is Peripheral Benzodiazepine Receptor (PBR) Gene Expression Involved in Breast Cancer Suppression by Dietary Soybean Protein. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada436892.

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Das, Salil. Is Peripheral Benzodiazepine Receptor (PBR) Gene Expression Involved in Breast Cancer Suppression by Dietary Soybean Protein? Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada457465.

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Viswanathan, Meera, Jennifer Cook Middleton, Alison Stuebe, et al. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions. Agency for Healthcare Research and Quality (AHRQ), 2021. http://dx.doi.org/10.23970/ahrqepccer236.

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Background. Untreated maternal mental health disorders can have devastating sequelae for the mother and child. For women who are currently or planning to become pregnant or are breastfeeding, a critical question is whether the benefits of treating psychiatric illness with pharmacologic interventions outweigh the harms for mother and child. Methods. We conducted a systematic review to assess the benefits and harms of pharmacologic interventions compared with placebo, no treatment, or other pharmacologic interventions for pregnant and postpartum women with mental health disorders. We searched fo
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Peng, ciyan, Sini Li, Jing Chen, et al. The Clinical Efficacy and Safety of Sixteen CPMs in Combination with Benzodiazepines/Non-Benzodiazepines for Chronic Adult Insomnia: A Multiple-Treatments Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0020.

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Li, Qu, Xue-Ping Ma, Alimujiang Simayi, Xiao-Li Wang, and Gui-Ping Xu. Comparative efficacy of various pharmacologic treatments of alcohol withdrawal syndrome: A systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.12.0010.

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Abstract:
Review question / Objective: Lorazepam and other benzodiazepines (BZDs) are considered the first choice for treatment of Alcohol withdrawal syndrome (AWS). But they have significant addiction potential and can cause fatal respiratory depression if used in large doses. The aim of our study is to conduct a network meta-analysis to provide some data support for the clinical treatment of AWS. The patients were persons with alcohol withdrawal. The intervention being studied must be a comparison of the efficacy of the two pharmacologic treatments. The study should not be included if two pharmacologi
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