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Relevant bibliographies by topics / Bioactive gla

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Journal articles
Dissertations / Theses
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Academic literature on the topic 'Bioactive gla'

Author: Grafiati

Published: 14 March 2023

Last updated: 31 July 2025

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Journal articles on the topic "Bioactive gla"

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Zhu, Weidong, Yi Zhang, Yueshan Li та Hao Wu. "Glaucocalyxin A Attenuates IL-1β-Induced Inflammatory Response and Cartilage Degradation in Osteoarthritis Chondrocytes via Inhibiting the Activation of NF-κB Signaling Pathway". Disease Markers 2022 (26 лютого 2022): 1–9. http://dx.doi.org/10.1155/2022/6516246.

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Glaucocalyxin A (GLA) is a bioactive natural compound with anti-inflammatory activity. Herein, the role of GLA in osteoarthritis (OA) was evaluated. Our results demonstrated that the IL-1β-induced inducible nitric oxide synthase (iNOS) and cyclooygenase-2 (COX-2) expression, two enzymes resulting in the release of nitric oxide (NO) and PGE2, were also prevented by GLA in chondrocytes. Moreover, GLA suppressed inflammatory cytokines production in chondrocytes. In addition, the elevated expressions of MMPs and ADAMTSs and the degradation of aggrecan and collagen II were reversed by GLA in chondr

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González-Fernández, María José, Ignacio Ortea та José Luis Guil-Guerrero. "α-Linolenic and γ-linolenic acids exercise differential antitumor effects on HT-29 human colorectal cancer cells". Toxicology Research 9, № 4 (2020): 474–83. http://dx.doi.org/10.1093/toxres/tfaa046.

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Abstract α-Linolenic acid (ALA, 18:3n-3) and γ-gamma linolenic acid (GLA, 18:3n-6) are polyunsaturated fatty acids (PUFA) that improve the human health. The present study focused on testing the in vitro antitumor actions of pure ALA and GLA on the HT-29 human colorectal cancer cell line. Cell viability was checked by MTT ((3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) test, cell membrane damage by the lactate dehydrogenase assay, apoptosis was tested by both caspase-3 activity trial and transmission electron microscopy images, and protein composition was analyzed by quantitativ

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Das, Undurti N. "“Cell Membrane Theory of Senescence” and the Role of Bioactive Lipids in Aging, and Aging Associated Diseases and Their Therapeutic Implications." Biomolecules 11, no. 2 (2021): 241. http://dx.doi.org/10.3390/biom11020241.

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Lipids are an essential constituent of the cell membrane of which polyunsaturated fatty acids (PUFAs) are the most important component. Activation of phospholipase A2 (PLA2) induces the release of PUFAs from the cell membrane that form precursors to both pro- and ant-inflammatory bioactive lipids that participate in several cellular processes. PUFAs GLA (gamma-linolenic acid), DGLA (dihomo-GLA), AA (arachidonic acid), EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are derived from dietary linoleic acid (LA) and alpha-linolenic acid (ALA) by the action of desaturases whose activity

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Kousparou, Christina, Maria Fyrilla, Anastasis Stephanou, and Ioannis Patrikios. "DHA/EPA (Omega-3) and LA/GLA (Omega-6) as Bioactive Molecules in Neurodegenerative Diseases." International Journal of Molecular Sciences 24, no. 13 (2023): 10717. http://dx.doi.org/10.3390/ijms241310717.

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Neurodegenerative diseases are characterized by neuroinflammation, neuronal depletion and oxidative stress. They coincide with subtle chronic or flaring inflammation, sometimes escalating with infiltrations of the immune system cells in the inflamed parts causing mild to severe or even lethal damage. Thus, neurodegenerative diseases show all features of autoimmune diseases. Prevalence of neurodegenerative diseases has dramatically increased in recent decades and unfortunately, the therapeutic efficacy and safety profile of available drugs is moderate. The beneficial effects of eicosapentaenoic

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Jayaraju, Kummu Jyothsna, and Beludari Mohammed Ishaq. "Analytical characterization of biomarkers in an optimized novel antidiabetic polyherbal formulation using high-performance thin-layer chromatography and liquid chromatography with tandem mass spectrometry." Egyptian Pharmaceutical Journal 20, no. 4 (2021): 329–38. http://dx.doi.org/10.4103/epj.epj_35_21.

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Background Diabetes mellitus is a chronic health issue that requires novel approaches to treatment and a multimodal approach to prevention. In the treatment of diabetes, a polyherbal formulation is the finest alternative medicine. A polyherbal formulation was developed in-house and evaluated for its antidiabetic potential on streptozotocin-induced diabetes rat. The same extract was now characterized analytically utilizing a variety of methods. Objective The goal of this study was to quantify the biomarkers in a novel antidiabetic polyherbal formulation made in-house with Cinnamonum zeylanicium

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Berzal, Gonzalo, Martín García-González, Natalia Castejón, Paz García-García, Gloria Fernández-Lorente, and Francisco J. Señoráns. "Biocatalysts Based on Immobilized Lipases for the Production of Ethyl Esters of Fatty Acids including Bioactive Gamma-Linolenic Acid from Borage Oil." Catalysts 13, no. 9 (2023): 1275. http://dx.doi.org/10.3390/catal13091275.

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In the present work, borage oil (Borago officinalis) was used as the main source of gamma linolenic acid (GLA) to obtain ethyl esters by enzymatic ethanolysis using immobilized enzymes for its application in the food industry. Commercial Thermomyces lanuginosus lipase (TLL) was compared to chemical ethanolysis in alkaline medium. In addition, TLL was immobilized by adsorption on hydrophobic porous support (Octadecyl-Sepabeads®) to compare the results. Fatty acid ethyl ester (FAEE) yields of both reactions were compared under the same conditions (25 °C and 200 rpm) and analyzed by GC-MS. Moreov

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Ciganović, Petar, Katarzyna Jakimiuk, Michał Tomczyk, and Marijana Zovko Končić. "Glycerolic Licorice Extracts as Active Cosmeceutical Ingredients: Extraction Optimization, Chemical Characterization, and Biological Activity." Antioxidants 8, no. 10 (2019): 445. http://dx.doi.org/10.3390/antiox8100445.

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A green ultrasound-assisted extraction (UAE) method using glycerol/water mixtures for extraction of licorice (Glycyrrhiza glabra) bioactive constituents was developed in this study. The response surface method, according to the Box-Behnken design, was employed to optimize the extraction parameters: glycerol concentration (X1), temperature (X2), and the amount of herbal drug used in the production (X3). The responses were content of total phenols (TP), TP extraction efficiency (TPy) and the content of licorice characteristic constituents, glabridin (Gla) and isoliquiritigenin (Iso). Response su

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Kalampounias, Georgios, Chrysavgi Gardeli, Spyridon Alexis, et al. "Poly-Unsaturated Fatty Acids (PUFAs) from Cunninghamella elegans Grown on Glycerol Induce Cell Death and Increase Intracellular Reactive Oxygen Species." Journal of Fungi 10, no. 2 (2024): 130. http://dx.doi.org/10.3390/jof10020130.

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Cunninghamella elegans NRRL-1393 is an oleaginous fungus able to synthesize and accumulate unsaturated fatty acids, amongst which the bioactive gamma-linolenic acid (GLA) has potential anti-cancer activities. C. elegans was cultured in shake-flask nitrogen-limited media with either glycerol or glucose (both at ≈60 g/L) employed as the sole substrate. The assimilation rate of both substrates was similar, as the total biomass production reached 13.0–13.5 g/L, c. 350 h after inoculation (for both instances, c. 27–29 g/L of substrate were consumed). Lipid production was slightly higher on glycerol

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Neha Kumari and Neelesh Kumar Maurya. "Cyanobacteria's beneficial impacts on human wellness." International Journal of Agricultural Invention 8, no. 2 (2023): 201–5. https://doi.org/10.46492/ijai/2023.8.2.9.

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Because of their colour, cyanobacteria are also known as blue-green algae (BGA). These are gram-positive prokaryotes. They manufacture their own food by photosynthesis and are rich in colours such as chlorophyll a, carotenoids, and phycobilins. Blue-green algae have been demonstrated to be useful in the treatment of hypertension and may be used as a protein supplement. Moreover, it is used to treat high levels of cholesterol or other fats (lipids) in the blood, diabetes, obesity, and a variety of other diseases. BGA are healthy natural products that are high in essential amino acids, gamma-lin

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Arshad, Ahmad Najar, Ashaq Mohd, Ahmad Bhat Nisar, et al. "A Diagnostic approach for same looking plants for their Pharmacognosy value." Indian Journal of Science and Technology 14, no. 14 (2021): 1105–15. https://doi.org/10.17485/IJST/v14i14.2346.

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Abstract <strong>Objective:</strong> To establish diagnostic features of same looking plants (C. gigantea and C. procera) and also to explore the diurnal influence on their Pharmacognosy values. <strong>Methodology:</strong> To meet the objectives, the characteristics of these plants were explored by macroscopic, microscopic (light microscopy), and also by physio-chemical parameters. The physiochemical analysis was performed with air dried leaves and flowers of C. gigantea and C. procera. The collected samples were used for the quantitative determination of ash value (water solu

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Dissertations / Theses on the topic "Bioactive gla"

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BARBERI, JACOPO. "Exploring proteins in Roughland: on the adsorption of proteins on biomaterials for osseointegration." Doctoral thesis, Politecnico di Torino, 2022. http://hdl.handle.net/11583/2970986.

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Stoor, Patricia. "Interactions between oral and nasal microorganisms and the bioactive glass S53P4 with special reference to nasal cavity surgery." Turku : Turun Yliopisto, 2001. http://catalog.hathitrust.org/api/volumes/oclc/47834263.html.

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Book chapters on the topic "Bioactive gla"

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Amanpour, Asghar, Hasim Kelebek, and Serkan Selli. "GLC/HPLC Methods for Saffron (Crocus sativus L.)." In Bioactive Molecules in Food. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-78030-6_42.

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Amanpour, Asghar, Hasim Kelebek, and Serkan Selli. "GLC/HPLC Methods for Saffron (Crocus sativus L.)." In Bioactive Molecules in Food. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-54528-8_42-1.

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Umam, Mr Abdul Hadi, Mr Josef Yakin, Mr Dhimanjit Sarma, and Dr Faruk Alam. "Antidiabetic Agents: Biological Macromolecules." In Pharmaceutical Science: Research and Innovation. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/psrich8.

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Diabetes mellitus, which is characterised by persistent hyperglycaemia, is a huge issue to the health of people all over the world. In spite of their efficacy, conventional diabetes treatments can come with a number of undesirable side effects and restrictions. Research into alternative medicines, such as the investigation of biological macromolecules with antidiabetic effects, has been accelerated as a result of this. This review looks into this fascinating field, investigating the many classifications of macromolecules as well as the possible methods by which they exhibit their positive effe

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Conference papers on the topic "Bioactive gla"

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Masand, Shirley, Jian Chen, Melitta Schachner, and David I. Shreiber. "A Bioactive Peptide Grafted Scaffold for Peripheral Nerve Regeneration." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53627.

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Despite this innate regenerative potential of the peripheral nervous system, functional recovery often remains incomplete, especially as the severity of injury increases. This has been attributed to a number of sources including the ingrowth of fibrous scar tissue, lack of mechanical support for emerging neurites, and the malrouted reinnervation of neurites towards inappropriate targets. While research in the field is broad, it is generally accepted that an optimal nerve guidance conduit to encourage regeneration should include both biological and mechanical support for emerging neurites and g

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Uzor, PF, and CO Nnadi. "Dereplication of Bioactive Markers from the Leaves of Anthocleista nobilis: Searching for new Bioactive Metabolites." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608074.

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Maniadaki, A., E. Kotali, and A. Kotali. "Bioactive boron compounds inspired from Nature." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759130.

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Liu, B., C. Zhang, K. Zeng, P. Tu, and Y. Jiang. "Bioactive coumarin derivatives from Murraya exotica." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608108.

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Arbain, D. "Bioactive Compounds from Sumatran Medicinal Plants." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608564.

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Rithichai, P., Y. Jirakiattikul, C. Sriboonthai, and A. Itharat. "Bioactive Compounds and Antioxidant in Hibiscus sabdariffa Leaf." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608056.

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Kwak, M., JS Kim, and TK Hyun. "Variation in bioactive compounds and bioactive principles of rosehip (Rosa rugosa Thunb.) during repening." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3400146.

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Fernandes, E., T. Ferreira, F. Martins, C. Pereira, and L. Custódio. "Cakile maritima seeds as a source of bioactive compounds." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759192.

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Ranarivelo, N., A. Tchinda, O. Bonnet, et al. "Hyperacanthus genus (Rubiaceae): an underexplored source of bioactive compounds." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759231.

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Gonda, T., B. Ötvös Sándor, and A. Hunyadi. "Synthesis of new, potentially bioactive chalcones as protoflavone analogues." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608257.

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