Academic literature on the topic 'Biosynthesis. Enzymology'

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Journal articles on the topic "Biosynthesis. Enzymology"

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Nakayama, Toru. "Enzymology of aurone biosynthesis." Journal of Bioscience and Bioengineering 94, no. 6 (2002): 487–91. http://dx.doi.org/10.1016/s1389-1723(02)80184-0.

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Schneider, Gunter, and Ylva Lindqvist. "Structural enzymology of biotin biosynthesis." FEBS Letters 495, no. 1-2 (2001): 7–11. http://dx.doi.org/10.1016/s0014-5793(01)02325-0.

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Reeves, Christopher D. "The Enzymology of Combinatorial Biosynthesis." Critical Reviews in Biotechnology 23, no. 2 (2003): 95–147. http://dx.doi.org/10.1080/713609311.

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Niemetz, Ruth, and Georg G. Gross. "Enzymology of gallotannin and ellagitannin biosynthesis." Phytochemistry 66, no. 17 (2005): 2001–11. http://dx.doi.org/10.1016/j.phytochem.2005.01.009.

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Leadlay, Peter F. "The Enzymology of Polyketide Antibiotic Biosynthesis." Biochemical Society Transactions 27, no. 1 (1999): A3. http://dx.doi.org/10.1042/bst027a003a.

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Crosa, Jorge H., and Christopher T. Walsh. "Genetics and Assembly Line Enzymology of Siderophore Biosynthesis in Bacteria." Microbiology and Molecular Biology Reviews 66, no. 2 (2002): 223–49. http://dx.doi.org/10.1128/mmbr.66.2.223-249.2002.

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SUMMARY The regulatory logic of siderophore biosynthetic genes in bacteria involves the universal repressor Fur, which acts together with iron as a negative regulator. However in other bacteria, in addition to the Fur-mediated mechanism of regulation, there is a concurrent positive regulation of iron transport and siderophore biosynthetic genes that occurs under conditions of iron deprivation. Despite these regulatory differences the mechanisms of siderophore biosynthesis follow the same fundamental enzymatic logic, which involves a series of elongating acyl-S-enzyme intermediates on multimodu
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Kershaw, Nadia J., Matthew E. C. Caines, Mark C. Sleeman, and Christopher J. Schofield. "The enzymology of clavam and carbapenem biosynthesis." Chemical Communications, no. 34 (2005): 4251. http://dx.doi.org/10.1039/b505964j.

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Minto, Robert E., and Craig A. Townsend. "Enzymology and Molecular Biology of Aflatoxin Biosynthesis." Chemical Reviews 97, no. 7 (1997): 2537–56. http://dx.doi.org/10.1021/cr960032y.

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Kutchan, T. M., H. Dittrich, D. Bracher, and M. H. Zenk. "Enzymology and molecular biology of alkaloid biosynthesis." Tetrahedron 47, no. 31 (1991): 5945–54. http://dx.doi.org/10.1016/s0040-4020(01)86487-5.

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Wilton, David. "Phospholipid biosynthesis (methods in enzymology, vol. 209)." FEBS Letters 316, no. 2 (1993): 198–99. http://dx.doi.org/10.1016/0014-5793(93)81217-n.

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Dissertations / Theses on the topic "Biosynthesis. Enzymology"

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Reva, Anna. "Enzymology of gentamicin biosynthesis." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/277902.

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Gentamicin C complex is a mixture of five structurally similar aminoglycoside antibiotics, gentamicins C1, C1a, C2, C2a, and C2b, produced by the actinomycete bacterium Micromonospora echinospora. It is established in clinical use and despite significant toxicity remains valuable to treat severe Gram-negative bacterial infections. There is a pressing need to develop novel versions of such antibiotics to combat the rise of resistance among pathogens. Engineering of the pathway requires a detailed knowledge of the genes, enzymes, and intermediates involved. The final steps of gentamicin biosynth
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Kanchanabanca, Chompoonik. "The enzymology of tetronic acid biosynthesis." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708500.

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Crokett, Nigel. "Molecular biology and enzymology of porphyrin biosynthesis." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334167.

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Jansson, Anna. "Structural enzymology of the biosynthesis of polyketide antibiotics /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-916-1/.

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Lazos, Orestis. "The enzymology of macrocyclic polyketide and siderophore biosynthesis." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608409.

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Slatcher, Guy. "The mechanistic enzymology of cytochrome P-450 aromatase." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307085.

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Mondal, Dibyendu. "Testing intermediates to unravel the mechanism of flavin-dependent thymidylate biosynthesis." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6478.

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In humans and most eukaryotes, thymidylate synthase (TSase) serves as a key enzyme that catalyzes the reductive methylation of deoxyuridine monophosphate (dUMP) to synthesize deoxythymidine monophosphate (dTMP), a key component of DNA. The N5, N10- methylene-5,6,7,8-tetrahydrofolate (MTHF) serves as both the methylene donor and the hydride donor while generating dihydrofolate (H2folate) as the byproduct. However, in 2002, Myllykallio reported the discovery of flavin-dependent thymidylate synthase (FDTS) that also functions to maintain the dTMP pool, although the mechanism is different. Since t
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Cheng, Qian. "In Vitro Reconstitution of the Entire Enterocin Biosynthetic Pathway: New Insights into Type II PKS Enzymology." Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/195469.

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Type II polyketide synthases (PKSs) are responsible for the generation of structurally diverse and clinically important aromatic polyketides. The bacteriostatic agent enterocin (enc) isolated from the marine microbe "Streptomyces maritimus" is derived from a rare benzoate primer unit and contains a unique nonaromatic caged core structure resulting from a Favorskii-like carbon skeleton rearrangement. The apparent diversion between enterocin biosynthesis and all other type II PKS pathways offered the opportunity to discover novel enzymatic strategies that may be exploited to diversify the chemic
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Koekemoer, Lizbe. "Characterization of prokaryotic pantothenate kinase enzymes and the development of type-specific inhibitors." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/18099.

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Thesis (PhD)--Stellenbosch University, 2011.<br>ENGLISH ABSTRACT: Pantothenate kinase (PanK) enzymes catalyze the first reaction in the five step biosynthesis of the essential cofactor coenzyme A. Enzymes representing each of the three identified PanK types have been studied and characterized and these PanK types exhibits a unique diversity between different organisms, therefore highlighting them as potential drug targets. In this study the type III PanK of specifically pathogenic bacteria were characterized with the goal of developing type-specific inhibitors. Several questions about the acti
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Henry, Luc. "Studies on enzymes mechanism and selectivity using synthetic substrate analogues." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:21234b44-3778-46c6-9a08-9351f6411f4e.

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Organic chemistry is a valuable tool for studying enzyme mechanisms. Upon incubation with a specific enzyme, synthetic substrate analogues labeled with heavy atoms or carrying extra functional groups can provide mechanistic insights. In the present work, new compounds were synthesised in order to study the mechanism and substrate selectivity of two enzymes: human γ-butyrobetaine hydroxylase and bacterial carboxymethylproline synthase. γ-Butyrobetaine hydroxylase (BBOX) is an Fe(II) and 2-oxoglutarate (2OG)-dependent oxygenase that catalyses the stereospecific hydroxylation of γ-butyrobetaine,
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Books on the topic "Biosynthesis. Enzymology"

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(Editor), John N. Abelson, Melvin I. Simon (Editor), Edward A. Dennis (Editor), and Dennis E. Vance (Editor), eds. Phospholipid Biosynthesis, Volume 209: Volume 209: Phospholipid Biosynthesis (Methods in Enzymology). Academic Press, 1992.

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Phospholipid Biosynthesis, Volume 209: Volume 209: Phospholipid Biosynthesis (Methods in Enzymology). Academic Press, 1992.

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Tang, Yi, and Christopher T. Walsh. Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery. Royal Society of Chemistry, The, 2017.

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(Editor), John N. Abelson, Melvin I. Simon (Editor), and Helmut Sies (Editor), eds. Carotenoids, Part B: Metabolism, Genetics, and Biosynthesis, Volume 214: Volume 214: Carotenoids Part B (Methods in Enzymology). Academic Press, 1993.

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Shen, Ben. LL-C10037Ü and MM 14201: Structure, biosynthesis and enzymology of two epoxysemiquinone antibiotics. 1990.

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Wise, Mitchell L. Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae. 1995.

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Shen, Ben. LL-C10037Ü and MM 14201: Structure, biosynthesis and enzymology of two epoxysemiquinone antibiotics. 1990.

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YAMANAKA, TATEO. Biochemistry Of Bacterial Cytochromes. Springer, 1992.

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Translation Initiation: Extract Systems and Molecular Genetics, Volume 429 (Methods in Enzymology). Academic Press, 2007.

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Translation Initiation: Reconstituted Systems and Biophysical Methods, Volume 430 (Methods in Enzymology). Academic Press, 2007.

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Book chapters on the topic "Biosynthesis. Enzymology"

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Gross, Georg G. "Enzymology of Gallotannin Biosynthesis." In ACS Symposium Series. American Chemical Society, 1989. http://dx.doi.org/10.1021/bk-1989-0399.ch007.

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Roberts, Margaret F. "Enzymology of Alkaloid Biosynthesis." In Alkaloids. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4757-2905-4_5.

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Stafford, Helen A. "The Enzymology of Proanthocyanidin Biosynthesis." In Chemistry and Significance of Condensed Tannins. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-7511-1_3.

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Scapin, Giovanna, and John S. Blanchard. "Enzymology of Bacterial Lysine Biosynthesis." In Advances in Enzymology - and Related Areas of Molecular Biology. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/9780470123188.ch8.

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Leete, Edward. "Alkaloid Biosynthesis." In Advances in Enzymology - and Related Areas of Molecular Biology. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/9780470122778.ch9.

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Till, Marisa, and Paul R. Race. "The Assembly Line Enzymology of Polyketide Biosynthesis." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3375-4_2.

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Archer, B. L., and B. G. Audley. "Biosynthesis of Rubber." In Advances in Enzymology - and Related Areas of Molecular Biology. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/9780470122747.ch5.

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Cane, David E. "The enzymology of the biosynthesis of natural products." In Enzyme Chemistry. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-1832-0_7.

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Popják, G., and J. W. Cornforth. "The Biosynthesis of Cholesterol." In Advances in Enzymology - and Related Areas of Molecular Biology. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/9780470122679.ch7.

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Saito, Yoshitaka, Shuzo Otani, and Shohei Otani. "Biosynthesis of Gramicidin S." In Advances in Enzymology - and Related Areas of Molecular Biology. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/9780470122785.ch7.

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Reports on the topic "Biosynthesis. Enzymology"

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Ray, P. M. Enzymology and molecular biology of cell wall biosynthesis. Progress report. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10134679.

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Dr. Peter M. Ray. Enzymology and Molecular Biology of Cell Wall Biosynthesis. Final Technical Report. Office of Scientific and Technical Information (OSTI), 2000. http://dx.doi.org/10.2172/756685.

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