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Relevant bibliographies by topics / Blood lymphocytes

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Academic literature on the topic 'Blood lymphocytes'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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Journal articles on the topic "Blood lymphocytes"

1

Spain, B. A., D. M. Soliman, R. A. Sidner, and H. L. Twigg. "Enhanced proliferation and IL-2 secretion by lung lymphocytes from HIV-infected subjects." American Journal of Physiology-Lung Cellular and Molecular Physiology 269, no. 4 (1995): L498—L506. http://dx.doi.org/10.1152/ajplung.1995.269.4.l498.

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Human immunodeficiency virus (HIV)-positive patients frequently develop a CD3+/CD8+ cytotoxic T cell lymphocytic alveolitis. This could occur through in situ expansion of lung lymphocytes. We evaluated lung and blood lymphocyte proliferation in asymptomatic HIV-infected individuals by measuring spontaneous and cytokine-induced tritiated thymidine incorporation. Interleukin (IL)-2 and IL-4 secretion was determined with the use of enzyme-linked immunosorbent assay, Western blotting, and immunoprecipitation techniques. Spontaneous proliferation by lung lymphocytes from HIV-positive patients was s

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Winther, Birgit, Donald J. Innes, John Bratsch, and Frederick G. Hayden. "Lymphocyte Subsets in the Nasal Mucosa and Peripheral Blood during Experimental Rhinovirus Infection." American Journal of Rhinology 6, no. 4 (1992): 149–56. http://dx.doi.org/10.2500/105065892781874621.

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The local cellular response during rhinovirus infection was studied with immunohistochemical staining of lymphocyte subpopulations in the lamina propria of the nasal mucosa (inferior turbinate) in 25 biopsies from volunteers with experimental rhinovirus colds and compared with biopsies from healthy volunteers. Biopsies from rhinovirus infected volunteers, taken either in the early phase of the infection (days 3 and 5) or during convalescence (day 14) were evaluated in a semiquantitative fashion for degree of infiltration. Lymphocyte subpopulations also were counted on coded specimens. During e

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Lucivero, G., G. Pierucci, and L. Bonomo. "Lymphocyte subsets in peripheral blood and pleural fluid." European Respiratory Journal 1, no. 4 (1988): 337–40. http://dx.doi.org/10.1183/09031936.93.01040337.

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We have examined the distribution of B and T lymphocytes, T-cells with helper/inducer (T4+) or suppressor/cytotoxic (T8+) phenotypes and a subset of cells with natural killer (NK) activity and positive for the Leu 7 (HNK-1) surface antigen in peripheral blood and in lymphocyte-rich pleural effusions of patients with tuberculosis or malignancies (mesothelioma and lung cancer with pleural metastasis). In individual patients, the percentages of T lymphocytes were uniformly higher in pleural effusions than in peripheral blood; however, lower percentages of B lymphocytes and cells positive for the

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Klein, Ami, Michael Lishner, Barbara Bruser, John E. Curtis, Dominick J. Amato, and Aaron Malkin. "Cortisol catabolism by lymphocytes of patients with chronic lymphocytic leukemia." Biochemistry and Cell Biology 68, no. 4 (1990): 810–13. http://dx.doi.org/10.1139/o90-118.

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A low rate of catabolism of cortisol by lymphocytes correlates with high sensitivity of the cells to the steroid and causes them to die at a greater rate than control samples. Since lymphocytes of patients with chronic lymphocytic leukemia respond to treatment with glucocorticosteroids and are cortisol sensitive, we attempted to see whether their capability to catabolize cortisol differs from that of normal lymphocytes. No difference was found between the two groups of cells with regard to the pattern of cortisol metabolites. However, the lymphocytes of the chronic lymphocytic leukemia groups

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Andrade, William N., Miles G. Johnston, and John B. Hay. "The Relationship of Blood Lymphocytes to the Recirculating Lymphocyte Pool." Blood 91, no. 5 (1998): 1653–61. http://dx.doi.org/10.1182/blood.v91.5.1653.

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Abstract Lymphocyte recirculation facilitates the detection and elimination of pathogens and the dissemination of immunologic memory. It is generally assumed that all small lymphocytes in the blood are actively recirculating, yet there is little quantitative data directly comparing the migration of this population with actively recirculating, lymph-derived lymphocytes. In this study blood lymphocytes were labeled with fluorescein isothiocyanate (FITC), and lymph lymphocytes were labeled with CM-DiI, reinfused intravenously, and monitored in blood and lymph. After equilibration the concentratio

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Andrade, William N., Miles G. Johnston, and John B. Hay. "The Relationship of Blood Lymphocytes to the Recirculating Lymphocyte Pool." Blood 91, no. 5 (1998): 1653–61. http://dx.doi.org/10.1182/blood.v91.5.1653.1653_1653_1661.

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Lymphocyte recirculation facilitates the detection and elimination of pathogens and the dissemination of immunologic memory. It is generally assumed that all small lymphocytes in the blood are actively recirculating, yet there is little quantitative data directly comparing the migration of this population with actively recirculating, lymph-derived lymphocytes. In this study blood lymphocytes were labeled with fluorescein isothiocyanate (FITC), and lymph lymphocytes were labeled with CM-DiI, reinfused intravenously, and monitored in blood and lymph. After equilibration the concentration of bloo

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Hay, John B., and William N. Andrade. "Lymphocyte recirculation, exercise, and immune responses." Canadian Journal of Physiology and Pharmacology 76, no. 5 (1998): 490–96. http://dx.doi.org/10.1139/y98-051.

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Alterations in leukocyte concentrations in the blood are associated with exercise, stress, and other pathophysiological perturbations. The continuous migration and redistribution of cells of the recirculating lymphocyte pool between the blood and lymphatic systems can be influenced by a variety of physiological, immunological, and pathological processes. The phenotypic distribution of lymphocyte subsets is not the same in blood, afferent lymph, and efferent lymph, and cell-tracking experiments have shown that lymphocytes vary in their migratory properties. The most comprehensive physiological

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Choccalingam, Chidambharam. "Volume, conductance, and scatter parameters of neoplastic and nonneoplastic lymphocytes using Coulter LH780." Journal of Laboratory Physicians 10, no. 01 (2018): 085–88. http://dx.doi.org/10.4103/jlp.jlp_65_17.

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Abstract PURPOSE: Automated hematology analyzers yield a complete hematological profile including a complete blood count and a differential white blood cell count. The differential count is based on analyses of three parameters, namely, volume, conductance, and scatter (VCS). We aimed to evaluate the VCS parameters, histograms, and scatterplots of neoplastic and nonneoplastic lymphocytes. MATERIAL AND METHODS: Patients were grouped into four categories, namely, acute lymphoblastic leukemia (ALL), chronic systemic disorders, chronic lymphocytic leukemia (CLL), and acute viral disease. Lymphocyt

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Mirkamali, Mona, Hamid Reza Momeni, Tahereh Etemadi, Ghasem Mosayebi, and Majid Komijani. "Involvement of caspase-3 in apoptosis of human lymphocytes exposed to cadmium chloride." Human & Experimental Toxicology 41 (January 2022): 096032712211217. http://dx.doi.org/10.1177/09603271221121796.

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Background Lymphocytes are a group of white blood cells with a variety of roles their integrity is crucial for the body’s immune responses. Cadmium, a heavy metal and environmental pollutant, is known as a toxicant to exert its adverse effects on some sort of cells including blood cells. Research Design In this study, human lymphocytes were divided into 3 groups: (1) lymphocytes at 0-h, (2) lymphocytes at 24 h (control), (3) lymphocytes treated with cadmium chloride (15 μM). Lymphocyte viability and plasma membrane integrity were assessed in these groups. In addition, the occurrence of apoptos

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Twigg, Homer L., Blake A. Spain, Diaa M. Soliman та ін. "Production of interferon-γ by lung lymphocytes in HIV-infected individuals". American Journal of Physiology-Lung Cellular and Molecular Physiology 276, № 2 (1999): L256—L262. http://dx.doi.org/10.1152/ajplung.1999.276.2.l256.

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A CD8+lymphocytic alveolitis occurs in up to 60% of asymptomatic human immunodeficiency virus (HIV)-infected individuals. Early in HIV infection, lymphocytes consist predominantly of cytotoxic T lymphocytes directed against HIV-infected targets. As HIV disease progresses, they are replaced by CD8+CD57+suppressor cells. Virus-specific cytotoxic T lymphocytes secrete interferon-γ (IFN-γ), an important cytokine in upregulating immune responses, primarily through macrophage activation. We examined the ability of lung and blood lymphocytes from HIV-positive patients at various stages of HIV infecti

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Dissertations / Theses on the topic "Blood lymphocytes"

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Seabrook, Timothy James. "The differential migration of blood and lymph lymphocytes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0016/NQ53778.pdf.

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Wongsriraksa, Anong. "Characterisation of nicotine binding sites on human blood lymphocytes." Thesis, University of Hertfordshire, 2008. http://hdl.handle.net/2299/1960.

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Nicotine exerts a therapeutic effect in ulcerative colitis (UC) but the mechanism underlying this effect, is not clear. However, this effect may imply that nicotine has some, as yet to be discovered, effect on the immune system. The aim of the work described in this thesis was to characterise the nicotinic acetylcholine receptors (nAChRs) on human peripheral blood lymphocytes in term of receptor subtype. To achieve this, a combination of radioligand binding assays, pharmacological and molecular biological techniques were used. The data obtained from the binding studies suggested that the prese

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Richards, Stephen John. "Immunophenotypic, genotypic and functional characteristics of normal, reactive and malignant large granular lymphocytes (LGL)." Thesis, Manchester Metropolitan University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260767.

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Gorfu, Gezahegn. "Interaction of human blood platelets, lymphocytes and monocytes with vascular laminin isoforms /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-119-7/.

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Wang, Eddie Chung Yern. "CD8'+, CD57'+ lymphocytes : a functional and phenotypic analysis in normal peripheral blood." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319575.

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Miller, Brian Douglas. "Rat Peripheral Blood Lymphocytes as a Surrogate for Expression of TCDD Inducible Genes." NCSU, 2005. http://www.lib.ncsu.edu/theses/available/etd-04292005-105927/.

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2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is persistent in the environment and the food chain resulting in a chronic exposure to human populations. The effects of this known human carcinogen are evaluated by measuring various TCDD-inducible endpoints. Cytochrome P450 1B1, a recently identified TCDD responsive gene, shows inducibility in both the rat and humans that is similar to Cytochrome P450 1A1, a widely accepted marker for TCDD responsiveness. In order to evaluate a Sprague Dawley rat model to predict human tissue effects with easily accessible human tissue, such as peripheral blood lymp

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Werner, Becker Marianne Patricia. "Response of Peripheral Blood Lymphocytes from RAO-affected Horses to b2-Agonist Stimulation." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/72984.

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Recurrent airway obstruction (RAO) affects middle-age horses, inducing bronchoconstriction and airway inflammation. Î²2-agonists like salbutamol are used as treatment, promoting airway smooth muscle (ASM) relaxation and bronchodilation. In addition to ASM, inflammatory cells express the Î²2-adrenoreceptors (Î²2-AR). In other species, Î²2-agonists promote peripheral blood lymphocyte (PBL) cytokine expression towards a pro-inflammatory phenotype. RAO horses are a good model for evaluating chronic changes in human asthma. However, little is known about the effect of Î²2-agonist stimulation on equ

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Luqmani, Raashid Ahmed. "Phenotypic studies of rheumatoid arthritis : analysis of peripheral blood lymphocytes and rheumatoid synovial membrane." Thesis, University of Nottingham, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317403.

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Llaudó, Vallmajor Inés. "P-Glycoprotein functional activity in peripheral blood lymphocytes. Role of immunosuppressants, pharmacogenomics and alloimmune response." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/134502.

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Both immunological and non immunological factors are involved in chronic allograft nephropathy such as donor specific alloreactivity, chronic inflammation and nephrotoxicity induced by anticalcineurinics. Different degrees of nephrotoxicity are related to immunosuppression and to the level of inhibition of the different transporter proteins such as MDR1, MRP1 and MRP2. Those proteins could be subjected to genetic inter-individual variability thus modifying pharmacokinetics parameters. Furthermore, optimal immunosuppressive dose could be predicted by genotype characterization of MDR1, MRP1 or M

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Le, Roux Jacques. "The analysis of radiation-induced micronuclei in peripheral blood lymphocytes for purpose of biological dosimetry." Master's thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/27038.

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In the investigation of radiation accidents, it is of great importance to estimate the dose absorbed by exposed persons in order to plan their therapy. Although occasionally in these situations physical dose measurements are possible, most often biological methods are required for dose estimation. The aim of this investigation was to assess the suitability of the cytokinesis blocked (CB) micronucleus assay as a biodosimetric method using lymphocytes irradiated in vivo. The approach adopted to achieve this was to estimate whole body doses by relating micronuclei yields in patients undergoing ra

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Books on the topic "Blood lymphocytes"

1

Benoit, Elna. Understanding the complete blood count: The white blood cells : red blood cells, white blood cells or platelets. Concept Media, 2006.

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Benoit, Elna. Understanding the complete blood count: The red blood cells : red blood cells, white blood cells or platelets. Concept Media, 2006.

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A, Schmitt Didier, and United States. National Aeronautics and Space Administration., eds. In vitro interleukin-1 and 2 production and interleukin 2 receptor expression in the rhesus monkey. National Aeronautics and Space Administration, 1996.

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Molfino, Nestor Alfredo. Variable (V[gamma]) region gene usage in bronchoalveolar lavage and peripheral blood lymphocytes of atopic asthmatic and healthy subjects. National Library of Canada, 1994.

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McFarland, R. T. The effects of donor blood age on T-lymphocyte subsets and HLA-DR expression on surgical patients requiring blood transfusions. The Author], 1988.

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Wylie, John D. C. Peripheral blood leucocyte values, lymphocyte subsets and macrophages in the neonate: Comparison with adult valuesusing the immuno-alkaline phosphatase - anti-alkaline phosphatase technique and differntial white cell counts. The Author], 1989.

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7

Andrade, William Noel. The relationship of blood lymphocytes to the recirculating lymphocyte pool. 1996.

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Harris, J. Robin. Blood Cell Biochemistry Volume 3: Lymphocytes and Granulocytes. Springer London, Limited, 2013.

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Harris, J. Robin. Blood Cell Biochemistry Volume 3: Lymphocytes and Granulocytes. Springer, 2012.

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Blood Cell Biochemistry, Volume 3: Lymphocytes and Granulocytes (Blood Cell Biochemistry). Springer, 1991.

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Book chapters on the topic "Blood lymphocytes"

1

Harnett, Margaret M. "Cellular Signaling Events in B Lymphocytes." In Blood Cell Biochemistry. Springer US, 1996. http://dx.doi.org/10.1007/978-0-585-31728-1_4.

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de Leij, L., B. J. Kroesen, T. H. The, et al. "Immune Targeting of T-Lymphocytes." In Immunology and Blood Transfusion. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-3094-7_13.

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de Labriolle-Vaylet, Cl, M. Sala-Trepat, M. T. Doloy, A. Petiet, and N. Colas-Linhart. "Radiobiologic Study of 99mTc-HMPAO Labelled Lymphocytes." In Radiolabeled Blood Elements. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2462-5_27.

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Sprent, Jonathan. "Migratory Properties and Radiosensitivity of Lymphocytes." In Radiolabeled Cellular Blood Elements. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-4922-8_3.

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Kim, Kwang-Myong, Mitsufumi Mayumi, and Haruki Mikawa. "IgE Receptors on Lymphocytes and IgE-Binding Factors." In Blood Cell Biochemistry. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3796-0_5.

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Söderström, Kalle, Anders Bucht, Thomas Hultman, et al. "Comparisons of the V-Delta-1 Expressing T-Cells in Synovial Fluid and Peripheral Blood of Patients with Chronic Arthritis." In T Lymphocytes. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3054-1_26.

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Beregi, E. "Age-Related Morphologic Changes in Lymphocytes." In Blood Cells, Rheology, and Aging. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-71790-1_14.

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Schmitt-Gräff, Annette, and Giulio Gabbiani. "Cytoskeletal Organization of Normal and Leukemic Lymphocytes and Lymphoblasts." In Blood Cell Biochemistry. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3796-0_3.

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Lotti, Marcello. "Neuropathy Target Esterase in Blood Lymphocytes." In Biological Monitoring for Pesticide Exposure. American Chemical Society, 1988. http://dx.doi.org/10.1021/bk-1988-0382.ch009.

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Lima, Lucimey, Francisco Obregón, Mary Urbina, Isabel Carreira, Edith Baccichet, and Solisbella Peña. "Taurine Concentration in Human Blood Peripheral Lymphocytes." In Advances in Experimental Medicine and Biology. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0077-3_38.

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Conference papers on the topic "Blood lymphocytes"

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Hubel, Allison, and Jeffrey McCullough. "Cryopreservation of Cultured Blood Cells for Use in Gene Therapy and Immunotherapy." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1318.

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Abstract The freezing characteristics of genetically manipulated lymphocytes and hematopoietic stem cells were studied. The water transport characteristics of stem cells which had been cultured and transduced with a therapeutic gene were different from that of a freshly isolated cells. Changes in the freezing characteristics for genetically transformed lymphocytes were also observed. Specifically, cryopreservation protocols developed for the fresh peripheral blood lymphocytes do not produce comparable survival rates for lymphocytes which have been cultured and transduced. These results indicat

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Filippi, J. F., D. Arnoux, N. Tubiana, et al. "PLASMINOGEN ACTIVATOR ACTIVITY OF NORMAL AND MALIGNANT MONONUCLEAR HUMAN CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643167.

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Plasminogen activators (PA) are thought to play a role in the invasive and metastatic properties of many types of cancer cells. Though, discrepancies in correlations between fibrinolytic activity and metastatic potential of malignant cells have been described.In this study, we evaluated both tissue type (tPA) and urokinase type (UK) cellular PA activities in different mononuclear cell types : normal T and B human peripheral lymphocytes, B cells from patients with chronic lymphocytic leukemia (CLL), human blood monocytes, alveolar macrophages, U 937, RAJI and JM cell 1ines.Mononuclear cells wer

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Aydar, S., S. Alataş, L. Numanoğlu, and A. Sönmezdağ. "EFFECT OF ORAL ANTICOAGULANTS ON STABLE ROSETTE FORMATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643271.

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Human peripheral blood T lymphacytes when cultered in the presence of mitogen Phytohemogglutinin (PHA) acquire the capacity to form E rosettes with sheep erythrocytes that are resistant to incubation at 37° C. Whereas human thymus lymphocytes form 37° C stable E rosettes. On the other hand, it is shown that the use of anticoagulants can prevent cancer metastases which brings forth the importance of explaining the relationship between the lymphocyte functions and anticoagulant action mecha-nismus. In order to investigate this relationship, we did a group af experiments with lymphocytes of norma

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Streletskaya, Elena A., Julia K. Novoderzhkina, Gennady N. Vishnyakov, Gennady G. Levin, and Gennady I. Kozinets. "Computed tomography of the periphery blood lymphocytes and erythrocytes." In EOS/SPIE European Biomedical Optics Week, edited by Israel Gannot, Yuri V. Gulyaev, Theodore G. Papazoglou, and Christiaan F. P. van Swol. SPIE, 2001. http://dx.doi.org/10.1117/12.413804.

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Kornev, A. A., V. V. Vysochinskaya, N. A. Knyazev, A. K. Emel'yanov, and A. A. Bogdanov. "Transfection of human peripheral blood T-lymphocytes with synthetic small interfering RNAs: selection of an effective technique." In Global science. Development and novelty. L-Journal, 2020. http://dx.doi.org/10.18411/gsdn-25-12-2020-04.

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It has been shown that the state of the human immune system and its activity determines the development, course and prognosis of many oncological diseases. To date, various immunotherapeutic approaches have been developed, of which the most promising is adoptive cell therapy (ACT). An increase in the effectiveness of this type of therapy could be achieved by using synthetic small interfering RNAs (siRNAs) to suppress the expression of key immune checkpoint (ICI) genes (PD1, CTL4) in T-lymphocytes, which are involved in cellular immunosuppression. However, there is a problem of selecting an eff

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Zhou, Jerry, Larissa Belov, Stephen J. Clarke, and Richard I. Christopherson. "Abstract C5: Surface profiles of colorectal cancer cells and inflammatory lymphocytes correlate with blood neutrophil/lymphocyte ratios." In Abstracts: Second AACR International Conference on Frontiers in Basic Cancer Research--Sep 14-18, 2011; San Francisco, CA. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.fbcr11-c5.

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Valenzuela Membrives, María del Mar, Abel Sanchez- Palencia Ramos, Francisco Perea García, Francisco Ruiz Cabello, Antonio Rodríguez, and María Esther Farez Vidal. "Peripheral blood lymphocytes indicate an immunosuppressive status in lung cancer." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa527.

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Ershova, A. V., and O. V. Berdyugina. "Subpopulation structure of blood lymphocytes at patients with lung tuberculosis." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa1081.

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Baranova, Elena, Alla Boreyko, Ivanka Ravnachka, Maria Saveleva, Carlos Granja та Claude Leroy. "Evaluation of γ-Induced Apoptosis in Human Peripheral Blood Lymphocytes". У NUCLEAR PHYSICS METHODS AND ACCELERATORS IN BIOLOGY AND MEDICINE: Fifth International Summer School on Nuclear Physics Methods and Accelerators in Biology and Medicine. AIP, 2010. http://dx.doi.org/10.1063/1.3295662.

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Al Sharifi, Liqaa, Haider Abdul Ridha, Ahmed Rashid, Sinan Muhsin, and Teeb Jaafer. "Role of CD200 and CD43 in Diagnosis and Prognosis of CLL and NHL Patients." In 5th International Conference on Biomedical and Health Sciences. Cihan University-Erbil, 2024. http://dx.doi.org/10.24086/biohs2024/paper.1403.

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Background: Chronic lymphoproliferative disorder (LPD), is a malignant disease of lymphocytes in the blood and lymphatic tissue. Chronic lymphocytic leukaemia, it is the commonest type of chronic lymphoproliferative disorder. Scoring by immunophenotyping is used to differentiate B-cell chronic lymphocytic leukemia from other B-Non-Hodgkin lymphomas. CD200 (OX2) is a glycoprotein of membrane, it is related to type I superfamily of immunoglobulin . CD43 (Sialophorin) is a sialoglycoprotein that is present on the surface of T lymphocytes, some B lymphocytes, granulocytes and monocytes, that play

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Reports on the topic "Blood lymphocytes"

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Avihingsanon, Yingyos, Jongkonnee Wongpiyabovorn, and Nattiya Hirankarn. Biomarker discovery in systemic lupus erythematosus: genome-methylation approaches : Research report. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.15.

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Discovery of novel biomarkers in lupus nephritis Biomarkers are needed for making diagnosis and prognosis. In lupus nephritis, conventional tests like urinalysis or serum creatinine remain inadequate for patient care. In this proposal, we focused on non-invasive tools like blood and urine mRNAs or proteins. We chose candidate genes involving regulatory T-cell, B-lymphocyte signatures or vascular protective factors. Expression of regulatory cell signature (FOXP3) in peripheral blood mononuclear cells is associated with activity of lupus nephritis. We found FOXP3 mRNA levels in PBMCs from patien

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Nelson, Marian R., Clark L. Gross, William J. Smith, and Susan A. Kelly. Determination of ATP Levels in Sulfur Mustard-Exposed Human Peripheral Blood Lymphocytes by a Chemiluminescent Assay. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada390626.

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Palmer, Guy H., Eugene Pipano, Terry F. McElwain, Varda Shkap, and Donald P. Knowles, Jr. Development of a Multivalent ISCOM Vaccine against Anaplasmosis. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568763.bard.

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Anaplasmosis is an arthropod+borne disease of cattle caused by the rickettsia Anaplasma marginale and an impediment to efficient production of healthy livestock in both Israel and the United States. Our research focuses on development of a recombinant membrane surface protein (MSP) immunogen to replace current vaccines derived from the blood of infected cattle. The risk of widespread transmission of both known and newly emergent pathogens has prevented licensure of live blood-based vaccines in the U.S. and is a major concern for their continued use in Israel. Briefly, we accomplished the follo

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Viksna, Ludmila, Oksana Kolesova, Aleksandrs Kolesovs, Ieva Vanaga, and Seda Arutjunana. Clinical characteristics of COVID-19 patients (Latvia, Spring 2020). Rīga Stradiņš University, 2020. http://dx.doi.org/10.25143/fk2/hnmlhh.

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Data include following variables: Demographics, epidemiological history, comorbidities, diagnosis, complications, and symptoms on admission to the hospital. Also, body’s temperature and SpO2. Blood cells: white cells count (WBC), neutrophils (Neu), lymphocytes (Ly), eosinophils (Eo) and monocytes (Mo), percentages of segmented and banded neutrophils, erythrocytes (RBC), platelet count (PLT), hemoglobin (Hb), and hematocrit (HCT); Inflammatory indicators: erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP); Tissue damage indicators: alanine aminotransferase (ALT), lactate dehydrog

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Splitter, Gary, Zeev Trainin, and Yacov Brenner. Lymphocyte Response to Genetically Engineered Bovine Leukemia Virus Proteins in Persistently Lymphocytic Cattle from Israel and the U.S. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570556.bard.

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The goal of this proposal was to identify proteins of BLV recognized by lymphocyte subpopulations and determine the contribution of these proteins to viral pathogenesis. Our hypothesis was that BLV pathogenesis is governed by the T-cell response and that the immune system likely plays an important role in controlling the utcome of infection. Our studies presented in ths final report demonstrate that T cell competency declines with advancing stages of infection. Dramatic differences were observed in lymphocyte proliferation to recombinant proteins encoded by BLV gag (p12, p15, and p24) and env

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Liang, BiYan, BiYan Liang, and Jian Wang. A Meta Analysis of the Efficacy of Tonic Method in Traditional Chinese Medicine for AIDS Immunological Nonresponses. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0077.

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Review question / Objective: To evaluate the efficacy of tonic method in treating AIDS immunological nonresponses. Eligibility criteria: ①Study type: RCT based on tonic method in TCM for AIDS INRs. The language was limited to Chinese and English. ②The research object: HIV/AIDS patients with any disease stage; the intervention objects were adults with no gender restrictions. ③Intervention measures: The treatment group was treated with tonic prescriptions combined with ART, including four types of prescriptions for nourishing qi, nourishing blood, nourishing yin, or nourishing yang; the dosage,

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Foote, Monica R., B. J. Nonnecke, M. A. Fowler, B. L. Miller, Donald C. Beitz, and W. R. Waters. Nutritional Modulation of the Proliferation and Activation of Blood Lymphocyte Subsets from Milk Replacer-Fed Calves. Iowa State University, 2005. http://dx.doi.org/10.31274/ans_air-180814-1381.

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From, E. L., L. S. Newman, and M. M. Mroz. Results of the analysis of the blood lymphocyte proliferation test data from the National Jewish Center. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/663518.

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Frome, EL. Results of The Analysis of The Blood Beryllium Lymphocyte Proliferation Test Data From The Oak Ridge Y-12 Study. Office of Scientific and Technical Information (OSTI), 2001. http://dx.doi.org/10.2172/814245.

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Noga, Edward J., Ramy R. Avtalion, and Michael Levy. Comparison of the Immune Response of Striped Bass and Hybrid Bass. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568749.bard.

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We developed methods for examining the pathophysical response of striped bass and hybrid bass to various forms of stress. This involved development of techniques for the measurement of lysozyme, mitogen blastogenesis, mixed lymphocyte reaction, and oxidative burst, which are important general indicators of systemic immune function. We also examined local immune defenses (epithelial integrity), as well as homeostatic indicators in blood, including osmotic balance and glucose. Acute stress resulted in significant perturbations in a number of parameters, including glucose, electrolytes, osmolarit

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