Academic literature on the topic 'Bone marrow infiltration'

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Journal articles on the topic "Bone marrow infiltration"

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Gerlach, Magdalena M., Darius Juskevicius, Visar Vela, Stefan Dirnhofer, and Alexandar Tzankov. "Bone Marrow Infiltration of Angioimmunoblastic T-Cell Lymphoma: Identification and Prognostic Impact of Histologic Patterns and Diagnostic Application of Ancillary Phenotypic and Molecular Analyses." Archives of Pathology & Laboratory Medicine 144, no. 5 (2019): 602–11. http://dx.doi.org/10.5858/arpa.2019-0007-oa.

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Context.— Angioimmunoblastic T-cell lymphomas originate from T follicular helper cells and express respective markers (BCL6, CD10, CXCL13, ICOS, and PD-1). Although commonly present, bone marrow involvement by angioimmunoblastic T-cell lymphoma can be diagnostically challenging. Additionally, only little is known about the distribution of T follicular helper cells in healthy and reactively changed bone marrows or in samples affected by other lymphomas. Objective.— To establish a diagnostic approach to reliably identify bone marrow infiltration of angioimmunoblastic T-cell lymphoma. Design.— We
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Dr., Amna Bakhtiar Dr. Maria Rehman Dr.Sadaf Zafar. "OUTCOME OF BONE MARROW BIOPSIES PERFORMED AT TERTIARY CARE HOSPITAL IN ISLAMABAD." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7841–44. https://doi.org/10.5281/zenodo.1402673.

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<em>Objective: To compare the outcome of bone marrow aspirate with the referral diagnosis and to study the pattern of different hematological abnormalities by bone marrow biopsy </em> <em>Study Design: Cross sectional descriptive study</em> <em>Duration: 1st January 2018 to 30th April 2018</em> <em>SETTING: Department of pathology, Pakistan institute of medical sciences, Islamabad</em> <em>Materials and Methods: Bone marrow biopsies of 180 patients performed during 4 month&rsquo;s period were assessed. Physician&rsquo;s referral and the final report of the bone marrow biopsy were recorded. Dat
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Kim, Ki Hwan, and Ho Young Lee. "Bone marrow infiltration of lymphoma." Korean Journal of Hematology 45, no. 3 (2010): 151. http://dx.doi.org/10.5045/kjh.2010.45.3.151.

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Reid, M. M., and A. D. J. Pearson. "Bone-marrow infiltration in neuroblastoma." Lancet 337, no. 8742 (1991): 681–82. http://dx.doi.org/10.1016/0140-6736(91)92506-w.

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Rathinasamy, Anchana, Steffen Dettling, Yingzi Ge, et al. "Emigration of tumor specific regulatory T cells from the bone marrow is triggered by S1P1 and correlates with their accumulation in breast tumors (TUM9P.1001)." Journal of Immunology 194, no. 1_Supplement (2015): 210.3. http://dx.doi.org/10.4049/jimmunol.194.supp.210.3.

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Abstract High regulatory T cell (Treg) infiltration in breast tumors is associated with reduced survival. However, the source of tumor infiltrating Treg and signals underlying their migration from lymphoid organs to the tumor tissue remain elusive. We here demonstrate that pronounced Treg infiltration in human breast tumors correlates with a selective reduction of tumor antigen specifc Treg from the bone marrow. Using MHC-II tumor peptide tetramers we furthermore show that tumor specific bone marrow Treg selectively express Sphingosine-1-phosphate receptor 1 (S1P1), the receptor that mediates
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Chulkova, S. V., E. N. Sholokhova, I. V. Poddubnaya, et al. "The relationship of lymphoid populations (infiltration) of the primary tumor with bone marrow immune responses in patients with breast cancer." Russian Journal of Biotherapy 22, no. 1 (2023): 49–61. http://dx.doi.org/10.17650/1726-9784-2023-22-1-49-61.

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Backgraund. Currently, immunotherapy is firmly established in the standard of cancer treatment. The basis for the appointment of immunotherapy are immunological tumor markers, which include lymphoid infiltration, a detailed study of which has received increasing attention in the last decade. An undoubted interest is the study of lymphoid infiltration, not only depending on the morpho-clinical parameters of breast cancer (BC), but also on the immune system of the bone marrow.Aim. To evaluate the infiltration of the primary tumor by lymphocytes depending on the morpho-clinical characteristics of
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Wang, Tiantian, Biao Zhou, Kui Zhang, Chen Yan, and Xiangzhen Guan. "Value of third-generation of VNCa dual-energy CT for differentiating diffuse marrow infiltration of multiple myeloma from red bone marrow." Medicine 103, no. 18 (2024): e38003. http://dx.doi.org/10.1097/md.0000000000038003.

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This study aims to investigate the ability of bone marrow imaging using third-generation dual-energy computed tomography (CT) virtual noncalcium (VNCa) to differentiate between multiple myeloma (MM) with diffuse bone marrow infiltration and red bone marrow (RBM). Bone marrow aspiration or follow-up results were used as reference. We retrospectively reviewed 188 regions of interests (ROIs) from 21 patients with confirmed MM and diffuse bone marrow infiltrations who underwent VNCa bone marrow imaging between May 2019 and September 2022. At the same time, we obtained 98 ROIs from 11 subjects with
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Moyo, Tamara K., Anass Bouchnita, Nathalie Eymard, Vitaly Volpert, and Mark J. Koury. "Effects of Bone Marrow Infiltration By Multiple Myeloma on Erythropoiesis." Blood 126, no. 23 (2015): 2143. http://dx.doi.org/10.1182/blood.v126.23.2143.2143.

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Abstract Diseases that infiltrate the bone marrow disrupt erythropoiesis leading to anemia. In multiple myeloma (MM), anemia severity can be correlated with degree of marrow infiltration by myeloma cells. Infiltrating MM may impair the function and structure of erythroblastic islands (EBIs), the marrow erythropoietic niches. An EBI consists of a central macrophage surrounded by colony-forming units-erythroid/proerythroblasts (CFU-E/pro-EBs) and their progeny, the differentiating erythroblasts. Cytokines produced by MM cells, such as Fas ligand (FL), tumor necrosis factor (TNF), and TNF-related
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Rahali, Fatima Zahra, Fatima Taher, Houda Nassih, and Sanae Sayagh. "Bone Marrow Infiltration in Rosai–Dorfman Disease." Case Reports in Hematology 2022 (December 15, 2022): 1–5. http://dx.doi.org/10.1155/2022/3420311.

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Rosai–Dorfman disease (RDD) is a rare and benign nonLangerhans cell histiocytosis. RDD commonly affects children and young adults typically presenting with massive, painless, and bilateral cervical lymphadenopathy. Extranodal involvement is present in about 40% of cases, and bone marrow infiltration is rare and unusual. RDD prognosis is usually good, however, involvement of bone marrow is associated with poor prognosis. We report a case of RDD with bone marrow involvement occurring in a 5-year-old female. She was admitted for asthenia, gingival bleeding, and diffuse bone pain without fever. Ph
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Mitani, Sachiko, Hitomi Kaneko, and Kazunori Imada. "Bone marrow infiltration of histiocytic sarcoma." Blood Research 53, no. 3 (2018): 185. http://dx.doi.org/10.5045/br.2018.53.3.185.

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Dissertations / Theses on the topic "Bone marrow infiltration"

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Oliveira, Claudia Teresa de [UNESP]. "Mielopatia infiltrativa por tumores não-hematológicos." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/88099.

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Made available in DSpace on 2014-06-11T19:23:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-04-01Bitstream added on 2014-06-13T20:29:57Z : No. of bitstreams: 1 oliveira_ct_me_botfm.pdf: 2586546 bytes, checksum: 0fa98dd82d7160414a5cffb84658a089 (MD5)<br>Fundação Amaral Carvalho<br>A infiltração de MO por tumores não-hematológicos tem sido descrita desde 1935 e, mais recentemente, desperta interesse da comunidade científica, pois inúmeros trabalhos têm relacionado a presença de células tumorais na MO com o processo de carcinogênese e a progressão tumoral. O presente estudo teve por
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Oliveira, Claudia Teresa de. "Mielopatia infiltrativa por tumores não-hematológicos /." Botucatu : [s.n.], 2009. http://hdl.handle.net/11449/88099.

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Orientador: Lígia Niero-Melo<br>Banca: Lucilene Silva Ruiz e Rezende<br>Banca: Eduardo Moreira de Queiroga<br>Resumo: A infiltração de MO por tumores não-hematológicos tem sido descrita desde 1935 e, mais recentemente, desperta interesse da comunidade científica, pois inúmeros trabalhos têm relacionado a presença de células tumorais na MO com o processo de carcinogênese e a progressão tumoral. O presente estudo teve por objetivo o levantamento dos casos com diagnóstico de mielopatia infiltrativa por tumores nãohematológicos, provenientes da Faculdade de Medicina de Botucatu - UNESP e do Hospit
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Tseng, Mei Lun, and 曾媺倫. "Infiltration of bone marrow-derived cell in tumor leaky vasculature." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/54637692695721639513.

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碩士<br>長庚大學<br>生物醫學研究所<br>99<br>Angiogenesis is essential for tumor exponential growth and metastasis. Although the process is known to involved multiple types bone marrow-derived cells (BMDC), the mechanism of how BMDC mediate neovascularization remains unclear. Previously, we have established a transplantable N-LMP1 tumor model. In this model system, an angiogenic period (from day7-14after tumor induction) and large infiltration of BMDC were formed. Based on leaky characteristic of tumor vessels, and that neovascularization requires αvβ3(CD51/CD61) –expressing BMDC, we hypothesized that there
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Books on the topic "Bone marrow infiltration"

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Ajithkumar, Thankamma, Ann Barrett, Helen Hatcher, and Natalie Cook. Paediatric malignancies. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235636.003.0015.

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Leukaemia is the commonest cancer (accounting for &gt;40% of cases) in children. It is a clonal proliferation of stem cells which leads to bone marrow failure and tissue infiltration.• Acute lymphoblastic leukaemia (ALL): 4/100,000• Acute myeloid leukaemia (AML): 0.7/100,000• Chronic myeloid leukaemia (CML): 0.2/100,000...
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Zhu, Nancy Y., and Cynthia Wu. Anaemia, cytopenias, and thrombosis in palliative medicine. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0083.

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Many haematological issues can complicate end-of-life care, including cytopenias and venous thromboembolism (VTE). Anaemia is very common and can significantly impact quality of life; causes include haemorrhage, iron deficiency, nutritional deficiencies, and bone marrow infiltration. Neutropenia from bone marrow failure as a result of disease infiltration or from chemotherapy effects can result in life-threatening infections. Finally, VTE is commonly seen in cancer patients as well as those who require prolonged hospitalization. Symptoms can cause discomfort, mortality is increased, and treatm
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Curry, Nicola, and Raza Alikhan. Bruising and bleeding. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0038.

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Bruising is extremely common and a normal response to injury. Perception of what is a normal level of bruising is subjective and it can be difficult to differentiate a patient with ‘normal’ bruising from a patient who has bruising due to a mild bleeding disorder. Patients with bruising/bleeding can be categorized into two clinical groups: those who have no other symptoms, in whom the cause is likely to be either a normal response to injury, or an isolated platelet disorder or clotting factor deficiency; and those who have additional symptoms, in whom haematological disease (e.g. thrombocytopen
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Book chapters on the topic "Bone marrow infiltration"

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Leung, Alexander K. C., Marcus Schmitt, Christie P. Thomas, et al. "Bone Marrow Infiltration." In Encyclopedia of Molecular Mechanisms of Disease. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6358.

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Ilaslan, Hakan, and Murali Sundaram. "Neoplastic Bone Marrow Infiltration." In Pediatric and Adult MRI Atlas of Bone Marrow. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-642-02740-6_3.

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Yoong, Philip, William Bugg, and Catherine A. Johnson. "Diffuse bone marrow infiltration on magnetic resonance imaging." In Mnemonics for Radiologists and FRCR 2B Viva Preparation. CRC Press, 2024. http://dx.doi.org/10.1201/9781846199189-23.

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Corrias, Maria Valeria. "Role of Bone Marrow Infiltration Detected by Sensitive Methods in Patients with Localized Neuroblastoma." In Pediatric Cancer. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-2418-1_24.

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Zhu, Nancy, and Cynthia Wu. "Anaemia, cytopenias, and thrombosis in palliative medicine." In Oxford Textbook of Palliative Medicine, edited by Nathan I. Cherny, Marie T. Fallon, Stein Kaasa, Russell K. Portenoy, and David C. Currow. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198821328.003.0088.

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Many haematological issues can complicate end of life care, including cytopenias and venous thromboembolism. Anaemia is very common and can significantly impact quality of life; causes include haemorrhage, iron deficiency, nutritional deficiencies, and bone marrow infiltration. Neutropenia from bone marrow failure as a result of disease infiltration or from chemotherapy effects can result in life-threatening infections. Finally, venous thromboembolism is commonly seen in cancer patients as well as those who require prolonged hospitalization. Symptoms can cause discomfort, mortality is increase
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Hatton, Chris. "Introduction to haematology." In Oxford Textbook of Medicine, edited by Chris Hatton and Deborah Hay. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0510.

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Haematology is the study of the composition, function, and diseases of the blood. The approach to a patient suspected of having a haematological disorder begins with taking a history (particularly noting fatigue, weight loss, fever, and history of bleeding) and performing a clinical examination (looking for signs of anaemia, infection, bleeding, and signs of cellular infiltration causing splenomegaly and/or lymphadenopathy). Key investigations include a full blood count, a blood film, and (in selected cases) examination of the bone marrow. Further diagnostic tests now routinely performed on bl
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Morandi, Fabio, Paola Scaruffi, Sara Stigliani, Barbara Carlini, and Maria Valeria. "Bone Marrow Infiltration in Neuroblastoma: Characteristics of Infiltrating Cells and Role of the Microenvironment." In Neuroblastoma. InTech, 2013. http://dx.doi.org/10.5772/55774.

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Rajkumar, S. Vincent, and Robert A. Kyle. "Plasma cell myeloma and related monoclonal gammopathies." In Oxford Textbook of Medicine, edited by Chris Hatton and Deborah Hay. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0527.

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The monoclonal gammopathies, also referred to as paraproteinaemias, are a group of neoplastic (or potentially neoplastic) diseases associated with the proliferation of a single clone of immunoglobulin-secreting plasma cells. Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic clonal plasma cell disorder characterized by a serum monoclonal (M)-protein level less than 30 g/litre, less than 10% of monoclonal bone marrow plasma cells, and no evidence of hypercalcaemia, renal insufficiency, anaemia, or bone lesions related to the plasma cell proliferative process, and no ev
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Krebs Jonathan, Bittrich Max, Dietrich Georg, et al. "Finding Needles in the Haystack: Identifying Patients with Rare Subtype of Multiple Myeloma Supported by a Data Warehouse and Information Extraction." In Studies in Health Technology and Informatics. IOS Press, 2018. https://doi.org/10.3233/978-1-61499-896-9-160.

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Finding patient cases with extremely rare pathologies is a laborious task. To decrease time spent on manually searching through thousands of discharge letters and reports, a data warehouse with a fast fulltext search index was queried. Our use case is to find &amp;ldquo;macrofocal myeloma&amp;rdquo;, i.e. Multiple Myeloma patients with few large lesions. We guessed the number of those patients in the University Hospital W&amp;uuml;rzburg at about 20. Most criteria were available in the data warehouse in an unstructured form requiring information extraction. 8 patient cases were found by search
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Strauchen, James A. "The Bone Marrow Biopsy." In Diagnostic Histopathology of the Bone Marrow. Oxford University PressNew York, NY, 1996. http://dx.doi.org/10.1093/oso/9780195097566.003.0001.

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Abstract The bone marrow core biopsy has emerged as an integral part of the evaluation of the hematologic patient (McFarland and Dameshek, 1958, Ellis et al, 1964). Bone marrow core biopsy is informative of details of marrow architecture and cellularity that are lost in the marrow aspirate smear. Bone marrow core biopsy is of particular value in the recognition of tumors and infiltrative processes involving the marrow, and is an indispensable tool for the staging of lymphomas and other malignant tumors with a significant incidence of marrow involvement. The Jamshidi-Swain bone marrow biopsy ne
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Conference papers on the topic "Bone marrow infiltration"

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Martinez-Martinez, F., J. Kybic, and L. Lambert. "Automatic detection of bone marrow infiltration by multiple myeloma detection in low-dose CT." In 2015 IEEE International Conference on Image Processing (ICIP). IEEE, 2015. http://dx.doi.org/10.1109/icip.2015.7351721.

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Matias, Rafael Bragança Rodrigues, Bruna Cardoso de Mattos Boccalini, Renata de Oliveira Costa, and Maria Fernanda Mélega Mingossi. "Mantle Cell Lymphoma recurrence and involvement of the central nervous system after bone marrow transplantation: case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.215.

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Introduction: Mantle cell lymphoma (MCL) is a subtype of uncommon nonHodgkin lymphoma. The involvement of the central nervous system (CNS) is uncommon in the course of the disease. Objective: To report a case of recurrence of MCL in the CNS as the first manifestation, after chemotherapy and bone marrow transplantation. Case report: Male patient, 49 years old, with no previous comorbidities diagnosed with stage IV MCL (bone marrow), submitted to chemotherapy and autologous transplantation. After two years, he sought out the neurology clinic with a complaint of blurred vision. Neurological exami
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Fervers, P., F. Fervers, J. Kottlors, et al. "Feasibility of artificial intelligence–supported assessment of bone marrow infiltration using dual-energy computed tomography in patients with evidence of monoclonal protein." In 103. Deutscher Röntgenkongress der Deutschen Röntgengesellschaft e. V. Georg Thieme Verlag, 2022. http://dx.doi.org/10.1055/s-0042-1749885.

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Stella, Isabela de Almeida, Vanessa de Freitas Moreira, Arthur da Veiga Kalil Coelho, et al. "An uncommon neurological manifestation of acute myeloid leukemia: longitudinally extensive transverse myelitis." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.638.

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Case presentation: A 68-year-old male patient presented with progressive difficulty walking over the course of two months, associated with sphincter dysfunction and weight loss of 25 kg. On examination, the patient presented fluctuation in the level of consciousness, bilateral papilla edema and asymmetric tetraparesis with crural predominance. During investigation, the magnetic resonance imaging showed areas of hypersignal in T2/FLAIR with foci of contrast uptake in the region of cerebellar peduncles and hemispheres, bulb and spinal cord of C1-C8, associated with diffuse meningeal enhancement.
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Alzoubi, Abdallah, Michie Toba, Kohtaro Abe, et al. "Dehydroepiandrosterone Inhibits The Infiltration Of Proliferative Bone Marrow-Derived Hematopoietic Stem Cells Into The Perivascular Space Of Remodeled Pulmonary Arteries Of SU5416/Hypoxia/Normoxia-Exposed Rats." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3422.

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Lima, Rodrigo Quevedo de, Eimi Nascimento Pacheco, Luiz Henrique Santana de Araujo, Cassio Fernando Paganini, and Katsuki Arima Tiscoski. "PLASMOBLASTIC LYMPHOMA WITH MAMMARY MANIFESTATION: A CASE REPORT." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1085.

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Introduction: Plasmoblastic lymphoma (PBL) is a rare entity of non-Hodking lymphoma that usually occurs in the oral cavity in immunosuppressed patients. The involvement of other organs has rarely been reported. The breast can be the site of the initial manifestation of many diseases and in cases like this report, lymphomas should be considered as differential diagnoses. Case report: D.S., female, 28 years old, quality reviewer, married, two children. Carrier of human immunodeficiency virus (HIV) with recent treatment. Intern for investigation of liver, duodenal and breast abnormalities. She ha
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Silva, Matheus Alves da, Eduardo Mesquita de Souza, Rafael Bragança Rodrigues Matias, et al. "Subacute fever and torpor in a hematological patient revealing atypical CLIPPERS with supratentorial involvement: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.403.

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Case report: A 62-year-old patient was transferred from another hospital with complaints of subacute torpor and fever two months after an allogeneic bone marrow transplant. He had the diagnosis of chronic myelomonocytic leukemia type 2 four years before the beginning of the neurological symptoms. The disease remained stable for two years after the diagnosis, but progressed and he was submitted to a bone marrow transplant. The complications during the procedure were a febrile neutropenia, that resolved with a cycle of antibiotics, and a reactivation of cytomegalovirus (CMV) infection (he had a
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Cieciera, M., R. Sutter, S. Wirth, T. Götschi, and N. A. Farshad-Amacker. "Bone Marrow Edema on MRI Predicts Immediate Outcome of Joint Infiltrations of the Foot." In 29th Annual Scientific Meeting of the European Society of Musculoskeletal Radiology (ESSR). Thieme Medical Publishers, Inc., 2022. http://dx.doi.org/10.1055/s-0042-1750678.

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Shafat, Manar S., Amina A. Abdul-Aziz, Christopher Marlien, Rachel Piddock, Kristian M. Bowles, and Stuart A. Rushworth. "Abstract 3131: Acute myeloid leukemia derived SDF1 repels tumor infiltrating lymphocytes in the bone marrow microenvironment." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-3131.

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Willier, Semjon Manuel, Paula Rothaemel, Jonas Wilhelm, et al. "Abstract A224: Bone marrow T-cells are tumor-infiltrating T-cells in pediatric patients with acute leukemia and their phenotype reflects immune evasion of leukemic blasts." In Abstracts: Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 30 - October 3, 2018; New York, NY. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr18-a224.

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Reports on the topic "Bone marrow infiltration"

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Pullarkat, Vinod. Phenotype and Function of Bone Marrow Infiltrating Lymphocytes in Chronic Myelogenous Leukemia. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada486408.

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Pullarkat, Vinod. Phenotype and Function of Bone Marrow Infiltrating Lymphocytes in Chronic Myelogenous Leukemia. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada471557.

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