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Dissertations / Theses on the topic 'C₂-C₃ alkenes'

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1

Wilkinson, Jon N. "Regioselective reactions at a diruthenium centre." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266954.

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2

Cavanagh, Craig. "Iron-mediated C-H coupling of arylsulfides and simple terminal alkenes." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/ironmediated-ch-coupling-of-arylsulfides-and-simple-terminal-alkenes(c9b77782-2d78-468e-a6b2-cf5bb5b63243).html.

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The use of directing groups in C-H functionalisation reactions provides a means to control the regioselectivity of such processes. Previous work in the Procter group reported the sulfoxide-directed metal-free C-H alkylation of arenes with organosilane nucleophiles. Attempts to expand this work by carrying out a similar process directly from the sulfide oxidation level, utilising an Fe(III) oxidant, a diarylsulfide and an alkene are discussed herein. During these investigations, it was discovered that the use of simple, unfunctionalised olefins selectively gave linear products of formal chloroa
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3

Okumura, Shogo. "Studies on Site-selective C-H Alkylation of Arenes with Alkenes." Kyoto University, 2019. http://hdl.handle.net/2433/242514.

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4

Reddy, S. R. "Enantioselective synthesis of bioactive molecules via hydrolytic kinetic resolution of alkoxy epoxides, dihydroxylation of alkenes and CuCN-mediated annulations in C-C, C-O bond formation." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2012. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/1910.

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5

Pawlikowski, Andrew V. "Developments in late metal-mediated C-N bond forming reactions /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8489.

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6

McGoldrick, Trevor A. "C-S lyase-mediated toxicity in primary cultures of proximal tubular cells." Thesis, University of Aberdeen, 2000. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602010.

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Halogenated alkenes are a group of commercially important chemicals. For example tetrafluoroethylene is the monomer used for the production of poly- tetrafluoroethylene, hexachloro-1:3-butadiene is a by-product from the manufacture of chlorinated solvents and perchloroethylene is widely used as a dry cleaning agent. Due to possible exposure to haloalkenes and the nephrotoxicity observed in animal studies, concern has been expressed for the potential of these compounds to cause toxicity to man. Animal studies have shown that these compounds undergo inter-organ metabolism and are bioactivated by
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7

Ma, Wenbo. "Transition Metal-Catalyzed C-H Functionalization for Sustainable Syntheses of Alkenes and Heterocycles." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://hdl.handle.net/11858/00-1735-0000-0022-5FDF-4.

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8

Fosu, Stacy C. "Functionalization of Arenes, Amines, Alkenes, and Alkynes Mediated by Radical Pathways." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555514456659022.

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9

Abed, Ali Abdine Racha. "Formation de liaisons C-C et C-hétéroatome par catalyse au cuivre ou en présence de complexes de ruthénium." Thesis, Montpellier, Ecole nationale supérieure de chimie, 2019. http://www.theses.fr/2019ENCM0014.

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Cette thèse se situe dans le cadre général de la recherche de nouvelles méthodes de synthèse peu couteuses et éco-compatibles permettant de valoriser certaines molécules en accédant à des composés intéressants dans plusieurs domaines comme la chimie des matériaux, pharmaceutique et organique. L’objectif consiste à créer des nouvelles liaisons C-C et C-hétéroatome sous un contrôle de sélectivité par catalyse avec des métaux de transition.Dans une première partie, une difonctionnalisation des alcènes a été réalisée par catalyse au cuivre pour aboutir à l’oxazolidinone qui comporte un squelette i
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10

Boer, Johannes Wietse de. "cis-Dihydroxylation and epoxidation of alkenes by manganese catalysts selectivity, reactivity and mechanism /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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11

Yip, Wing-ping, and 葉永平. "Alkane C-H bond oxidations and alkene dihydroxylations by oxorutheniumcomplexes of chelating tertiary amine ligands." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31246254.

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12

Niwetmarin, Worawat. "(-)-Cytisine : an entry to a multipoint chiral scaffold : Zweifel olefination towards functionalised alkenes and C-glycals." Thesis, University of Bristol, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730848.

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13

Aguiló, Carreras Joan. "Ruthenium Complexes with N/C-donor Ligands: Redox Catalysts for Water Oxidation and the Epoxidation of Alkenes." Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/113481.

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Un dels reptes més ambiciosos que té avui en dia la comunitat científica és millorar el coneixement de la reacció d’oxidació de l’aigua que dóna lloc a oxigen, protons i electrons. D’altra banda els epòxids son intermedis de reaccions diverses en la indústria química, particularment per a la síntesi de diversos polímers i “fine chemicals” com ara productes farmacèutics, additius alimentaris o fragàncies. Els aquo complexes mononuclears i dinuclears de ruteni amb lligands polipiridílics han estat estudiats a fons pel nostre grup de recerca i d’altres, convertint-se en catalitzadors útils per a
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14

Li, Haoran. "Pd-catalyzed C-H bond functionalizations of (hetero)arenes and alkenes : A one step access to poly(hetero)aromatics and styrene derivatives." Thesis, Rennes, Ecole nationale supérieure de chimie, 2020. http://www.theses.fr/2020ENCR0068.

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Afin d'expliquer le contexte de mon travail de recherche, j'ai résumé dans le premier chapitre des informations mécanistiques générales sur l'arylation des liaisons C-H catalysée par le palladium et j'ai détaillé certains travaux sur l'arylation directe en relation avec mes travaux. Mes objectifs étaient d'étudier la réactivité de nouvelles unités synthétiques permettant l'accès direct à des composés bi-(hétéro)aryls ou à des dérivés du styrène. Ensuite, dans les chapitres 2 à 6, j'ai résumé mes travaux de recherche. J'ai étudié l’arylation directes en C2 du Methoxsalen par des chlorures de be
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15

Xing, Dong, and 邢栋. "Transition metal-catalyzed C-N bond formation via addition of nitrogennucleophiles towards alkenes and related tandem cyclization reactions." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46589156.

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16

Patil, Shradha Vasant. "Radical additions of hydrocarbons, ethers and acetals to alkenes via allyl transfer reaction: A new chain reaction for C-H bond functionalization." Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/50658.

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Functionalization of hydrocarbons via a free-radical based allyl transfer reaction using various allyl bromide substrates has been previously studied. The work described in this dissertation focuses on the replacement of Br by phthalimido-N-oxyl (PINO ) which helps make this chemistry environmentally friendly. To replace Br with PINO , replacement of previously used allyl-bromide substrates with new allyl-PINO substrates were necessary. Various allyl- PINO compounds were synthesized and the use of these allyl-phthalimido-N-oxyl (allyl-PINO) compounds for the functionalization of various alky
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17

Ma, Wenbo [Verfasser], Lutz [Akademischer Betreuer] Ackermann, and Dietmar [Akademischer Betreuer] Stalke. "Transition Metal-Catalyzed C-H Functionalization for Sustainable Syntheses of Alkenes and Heterocycles / Wenbo Ma. Gutachter: Lutz Ackermann ; Dietmar Stalke. Betreuer: Lutz Ackermann." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/107099619X/34.

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18

Derrien, Nolwenn. "Palladium catalysed carbonylation of terminal alkenes to α,β-unsaturated esters, &, Allylic C-H functionalisation of unsaturated hydrazine carboxylates to vinyl isoxasolidines". Thesis, Loughborough University, 2014. https://dspace.lboro.ac.uk/2134/14660.

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In the first part of the thesis, the aim was to devise a new simple catalytic system based on palladium to allow insertion of carbon monoxide in the presence of an alcohol into unsaturated systems with retention of the double bond to give an unsaturated ester. The process is known as oxidative carbonylation. To allow the process to become catalytic, the palladium needs to be reoxidised in situ. Optimal conditions for the catalytic system were developed and a wide range of substrates have been examined. Simple terminal alkenes and alkenes bearing functional group have been successfully carbonyl
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19

Poutrel, Pauline. "Réduction du motif vinyl-CF₃ : vers la synthèse catalytique énantiosélective de centres C-CF₃ et la synthèse diastéréosélective de monofluoroalcènes terminaux Copper‐catalyzed enantioselective formation of C−CF3 centers from β‐CF3‐substituted acrylates and acrylonitriles Stereoselective synthesis of terminal monofluoroalkenes from trifluoromethylated alkenes". Thesis, Normandie, 2020. http://www.theses.fr/2020NORMIR07.

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Ces dernières années, la chimie du fluor est devenue un domaine clé de recherche de par la présence croissante de l’atome du fluor dans les molécules issues de l’agrochimie, de l’industrie pharmaceutique et des matériaux. Il est alors nécessaire de développer de nouvelles méthodologies permettant la synthèse de ces molécules fluorées. Dans notre cas, il s’agit de mettre au point des procédures permettant l’obtention de synthons d’une part avec un centre stéréogène contrôlé comportant un motif trifluorométhyle, d’autre part avec un motif monofluoroalcène terminal. Dans un premier temps, nous av
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20

Jiao, Lin-Yu [Verfasser], Martin [Akademischer Betreuer] Oestreich, and Mathias [Akademischer Betreuer] Christmann. "Oxidative palladium(II) catalyzed cross dehydrogenative couplings of indolines with arenes and alkenes at the C-7 position / Lin-Yu Jiao. Gutachter: Martin Oestreich ; Mathias Christmann. Betreuer: Martin Oestreich." Berlin : Technische Universität Berlin, 2015. http://d-nb.info/1077040172/34.

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21

Skhiri, Aymen. "Réactivité des chlorures de benzènesulfonyle pour l'accès à des hétéroarènes et alcènes arylés via des réactions pallado-catalysées." Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1S080.

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Au cours de cette thèse, nous nous sommes intéressés à la synthèse d’hétérocycles arylés via l’activation de liaisons sp2 C-H d’hétéroaromatiques et à la synthèse d’alcènes arylés halo-substitués catalysée par le palladium. Les produits obtenus sont considérés comme des briques moléculaires, intéressantes pour les biochimistes, ainsi que pour la préparation de matériaux. Le système catalytique Pd(MeCN)2Cl2/Li2CO3/dioxane permet l’accès direct à une grande variété de molécules arylées à partir d’hétéroarènes ou d’alcènes et de chlorures de benzènesulfonyle. Nous avons mis au point une méthode p
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22

Henderson, William Howell. "Palladium-Mediated C-H Activations." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1318003095.

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23

Schinkel, Marvin. "Rutheniumkatalysierte Addition von nicht aktivierten C(sp²)–H- und C(sp³)–H-Bindungen an Alkene." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://hdl.handle.net/11858/00-1735-0000-0015-A380-B.

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24

Kurlemann, Nils. "Evaluation of C-C-bond coupling enzymes as reversibly immobilised biocatalysts and for the application in a coupled asymmetric alkene oxidation." Berlin mbv, 2008. http://d-nb.info/990627527/04.

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25

Schinkel, Marvin [Verfasser], Lutz [Akademischer Betreuer] Ackermann, and Ulf [Akademischer Betreuer] Diederichsen. "Rutheniumkatalysierte Addition von nicht aktivierten C(sp²)–H- und C(sp³)–H-Bindungen an Alkene / Marvin Schinkel. Gutachter: Lutz Ackermann ; Ulf Diederichsen. Betreuer: Lutz Ackermann." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044306866/34.

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26

Wu, Fan. "Iodide-Catalyzed Alkene Oxyamination Reactions for the Synthesis of Nitrogen-Containing Heterocycles." University of Toledo / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1576248441561743.

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27

Nakajima, Katsumasa. "Use of an acetylenic sulfone as an alkene dipole equivalent in the total synthesis of (±)-pumiliotoxin C." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq20844.pdf.

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28

Pfeiffer, Jennifer Y. "The synthesis of 2-epi-pumiliotoxin C via intramolecular alkene Cope-type hydroamination, and, New routes toward ketonitrones." Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28495.

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Despite recent advances in the field, the hydroamination methodology has not yet reached its full potential. This thesis focuses on new investigations in Cope-type hydroamination by first examining six-membered ring formation in order to explore and expand the scope of intramolecular Cope-type hydroamination of disubstituted olefins. This objective was achieved by synthesizing pumiliotoxin C (+/-)-3 and its epimer (+/-)-2 through the cyclization of a hydroxylamine precursor (+/-)-1 under transition metal-free reaction conditions.* In the second chapter we discuss the scarcity of methods to mak
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29

Prat, Casellas Irene. "Bioinspired non-heme iron catalysts for challenging oxidative transformations: mechanistic studies and catalytic applications on selective alkane hydroxylation and alkene cis-dihydroxilation." Doctoral thesis, Universitat de Girona, 2013. http://hdl.handle.net/10803/117778.

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The functionalization of hydrocarbons in a sustainable manner is one of the main challenges for chemists. Their abundance in nature as natural gas or crude oil makes them the most convenient chemical feedstock. The oxidation of hydrocarbons is one of the most interesting reactions, because the introduction of an oxygen atom introduces functionality in these molecules, increasing their value as reagents for further chemical transformation. However, these reactions are fundamentally difficult due to the low reactivity of alkyl C-H bonds. Current available methodologies involve highly reactive-ox
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30

Larsson, Johanna M. "Transition metal-catalyzed allylic and vinylic functionalization : Method development and mechanistic investigations." Doctoral thesis, Stockholms universitet, Institutionen för organisk kemi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-89524.

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The use of small molecule building blocks in, for example, pharmaceutical research and new material development, creates a need for new and improved organic synthesis methods. The use of transition metals as mediators and catalysts opens up new reaction pathways that have made the synthesis of completely new compounds possible as well as greatly improved the synthetic routes to known compounds. Herein, the development of new metal-mediated and catalyzed reactions for construction of vinylic and allylic carbon-carbon and carbon-heteroatom bonds is described.  The use of iodonium salts as coupli
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31

Gu, Xiaodong. "Oxidative lipid fragmentation; New mechanisms, synthesis and reactions of putative intermediates." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1275497811.

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32

Neouchy, Zeïna. "Couplage croisé d’éthers d’énol méthyliques par activation de liaisons C(sp2)-OCH3 catalysée par le nickel et Synthèse d’amines α-trifluorométhylées acycliques optiquement activespar réarrangement de β-aminoalcools α-trifluorométhylés". Thesis, Paris Sciences et Lettres (ComUE), 2018. http://www.theses.fr/2018PSLET016.

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En chimie organique, le développement de méthodes de synthèse robustes et respectueuses de l’environnement a toujours été un défi. De plus, en chimie médicinale, la mise au point de méthodes de synthèse de synthons fluorés de haute valeur ajoutée sont importantes pour avoir accès à des composés bioactifs. Dans ce manuscrit, nous présentons des méthodes efficaces et faciles à mettre en œuvre pour la formation de liaisons carbone-carbone catalysée par le nickel et la formation de liaisons carbone hétéroatome par un réarrangement de β aminoalcools α-trifluorométhylés.Nous avons montré que le coup
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33

Lin, Hong. "An improved procedure for the conversion of alkenes and glycals to 12-diazides using Mn(OAc)?·2H?O in acetonitrile : total synthesis of (?)-FR901483 total synthesis of TAN1251A, B, C and D /." 2000.

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34

Tripathi, Chandra Bhushan. "Lewis Base and Hydrogen-Bonding Catalysis by Thioureas : From Chemoselective Alcohol Oxidation to Asymmetric Iodofunctionalizations of Alkenes and Dienes." Thesis, 2015. http://etd.iisc.ac.in/handle/2005/4078.

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35

Verma, Piyush Kumar. "Cobalt-nhc Complexes and Diazabutadienes in Activation of Mono/Diboron Compounds and Their Application in C-b Coupling Reactions." Thesis, 2021. https://etd.iisc.ac.in/handle/2005/5241.

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Boronic acid(esters) have been well recognized as an indispensable coupling partner in the Suzuki-Miyaura cross coupling reactions producing a vast spectrum of molecules, applicable in the diverse field ranging from medicinal to materials sciences.[1] Transition metal catalyzed synthesis of boronic esters from diborons with the assistance of bases is a well-established methodology[2]. In this thesis, the cobalt-N-Heterocyclic carbene complexes catalyzed borylation of organic compounds and interaction of diazabutadienes with diboron compounds will be discussed. (i) In the first section, Co(IM
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36

Friedman, Adam Alexander. "Rhodium and Palladium Catalysed Domino Reactions of Alkenyl Pyridines and Alkenyl Pyrazines." Thesis, 2013. http://hdl.handle.net/1807/42841.

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Domino catalysis is an ideal strategy in the synthesis of heterocyclic scaffolds, as multiple bonds can be formed under a single set of reaction conditions. In this work, we present the development of two novel domino processes which afford access to aza-analogues of the dihydrodibenzoxepine motif. Careful optimisation revealed that the Rh catalysed hydroarylation proceeds under mild conditions as compared to the C-O coupling. Furthermore, Pd was not required for the C-O bond formation when using alkenyl pyrazines as substrates. Variation of the substituents on both the heterocycle and on the
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37

Lin, Yung-Hui, and 林詠惠. "Tandem Alkene Isomerization/C-H Bond Activation Based on Nickel-Aluminum Bimetallic Catalysis." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/6dc778.

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碩士<br>國立交通大學<br>應用化學系碩博士班<br>102<br>In this thesis, tandem alkene isomerization and C-H functionalizaton of N-methylbenzimidazole by nickel catalysts was developed. We obtained different products by adding different ligands and Lewis acids. In the absence of Lewis acid, we obtained branched-chain derivatives of benzimidazole due to occurrence of olefin isomerization in this system. On the other hand, we obtained linear-chain derivatives of benzimidazole by adding Lewis acid and bulky ligand. We speculated that olefin isomerization process is faster than C-H bond activation without addition of
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38

Feng, Ying-hsuan, and 馮盈萱. "Palladium-Catalyzed Intramolecular Annulation of Alkenyl-Substituted Heterocycles via Double C-H Activation." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/04098648837485815249.

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碩士<br>國立臺灣科技大學<br>應用科技研究所<br>102<br>Benzimidazole derivatives are ubiquitous in pharmaceutical molecules. In this thesis, we develop a novel intramolecular annulation of alkenyl-substituted benzimidazoles via double C-H bond activation. Intramolecular cyclization, occurring between the C2 position of benzimidazole and the alkene at the side arm, is catalyzed by Pd(OAc)2 without any bases, acids or ligands. In comparison with previous reports reacting with arenes, we successfully perform intramolecular double C-H bond activation between benzimidazoles and alkenes with regioselectivity. Tricycli
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39

Thenraj, M. "A Computational Study of C-H Binding, C-H Activation and Fluxional Processes of d6 Half- Sandwich Complexes." Thesis, 2014. https://etd.iisc.ac.in/handle/2005/2796.

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Significant developments have been made in the field of C–H activation. However, various disadvantages, mainly low reactivity and selectivity, limit their usage in large-scale synthesis. It is crucial to understand the mechanisms and the nature of the transient species involved in the C–H activation paths to develop effective catalytic routes for homogeneous C–H functionalization reactions. Computational techniques are employed in this study to throw light on these processes. Chapter 1 briefly introduces C–H activation and functionalization reactions. After classifying the reactions on the b
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40

Thenraj, M. "A Computational Study of C-H Binding, C-H Activation and Fluxional Processes of d6 Half- Sandwich Complexes." Thesis, 2014. http://hdl.handle.net/2005/2796.

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Significant developments have been made in the field of C–H activation. However, various disadvantages, mainly low reactivity and selectivity, limit their usage in large-scale synthesis. It is crucial to understand the mechanisms and the nature of the transient species involved in the C–H activation paths to develop effective catalytic routes for homogeneous C–H functionalization reactions. Computational techniques are employed in this study to throw light on these processes. Chapter 1 briefly introduces C–H activation and functionalization reactions. After classifying the reactions on the ba
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41

Pelczar, Elizabeth M. "Studies of PNP and PCP pincer complexes synthesis and C-H activation potential of PNP pincer complexes and a PCP pincer complex applied to alkene hydrogenation." 2008. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.17214.

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