Relevant bibliographies by topics / Calcium Channel Blockers – pharmacokinetics

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Academic literature on the topic 'Calcium Channel Blockers – pharmacokinetics'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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Journal articles on the topic "Calcium Channel Blockers – pharmacokinetics"

Hunt, Bernard A., Michael B. Bottorff, Vanessa L. Herring, Timothy H. Self, and Richard L. Lalonde. "Effects of calcium channel blockers on the pharmacokinetics of propranolol stereoisomers." Clinical Pharmacology and Therapeutics 47, no. 5 (1990): 584–91. http://dx.doi.org/10.1038/clpt.1990.79.

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ENOMOTO, Nobuo, Mitsuhiro YOKOTA, Iwao SOTOBATA, Junki GOTO, Kazuya ANDO, and Itsuro SOBUE. "Effects of calcium channel blockers on the pharmacokinetics of oral .BETA.-methyldigoxin." Nihon Naika Gakkai Zasshi 77, no. 6 (1988): 781–87. http://dx.doi.org/10.2169/naika.77.781.

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Cachat, Francois, and Alda Tufro. "Phenytoin/Isradipine Interaction Causing Severe Neurologic Toxicity." Annals of Pharmacotherapy 36, no. 9 (2002): 1399–402. http://dx.doi.org/10.1345/aph.1c012.

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OBJECTIVE: To report a young man on phenytoin who developed acute neurologic symptoms after isradipine was introduced to his treatment regimen and discuss the possible causes of this drug interaction. CASE SUMMARY: A 21-year-old white man, with propionic acidemia and seizures treated with phenytoin and carbamazepine, was started on isradipine for essential hypertension. Soon thereafter, he developed acute and severe lethargy, ataxia, dysarthria, and weakness that resolved once isradipine was withheld. Phenytoin concentrations were within normal limits or elevated, despite sequential reductions

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Avdeeva, O. I., M. N. Makarova, I. E. Makarenko, P. V. Burenkov, M. G. Shubina, and V. A. Kashkin. "TTOXICOLOGICAL EVALUATION OF COMBINATION OF AMLODIPINE CALCIUM CHANNELS BLOCKER WITH ANGIOTENSIN RECEPTOR BLOCKERS." Toxicological Review, no. 1 (February 28, 2016): 13–17. http://dx.doi.org/10.36946/0869-7922-2016-1-13-17.

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The article summarizes experimental data on toxicological interactions of blocker of amplodipine slow calcium channels with angiotensin II (AT1 subtype) receptors blockers (valsartan and losartan). Toxicity studies were performed in outbred rats after a single intragastric administration in doses permitting to estimate lethal doses for the objects under investigation (amlodipine, valsartan, losartan, amlodipine+ losartan 1:10, amlodipine+ losartan 1:20, amlodipine + valsartan 1:16, amlodipine + valsartan 1:32). Based on the research outcome, the possibility of different types of toxicological

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GLESBY, M., J. ABERG, M. KENDALL, et al. "Pharmacokinetic interactions between indinavir plus ritonavir and calcium channel blockers." Clinical Pharmacology & Therapeutics 78, no. 2 (2005): 143–53. http://dx.doi.org/10.1016/j.clpt.2005.04.005.

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Azuma, Junichi, Isamu Yamamoto, Takahiro Watase, et al. "Effects of grapefruit juice on the pharmacokinetics of the calcium channel blockers nifedipine and nisoldipine." Current Therapeutic Research 59, no. 9 (1998): 619–34. http://dx.doi.org/10.1016/s0011-393x(98)85060-1.

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Deslandes, A., F. Camus, C. Lacroix, C. Carbon, and R. Farinotti. "Effects of nifedipine and diltiazem on pharmacokinetics of cefpodoxime following its oral administration." Antimicrobial Agents and Chemotherapy 40, no. 12 (1996): 2879–81. http://dx.doi.org/10.1128/aac.40.12.2879.

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We compared the effects of nifedipine and diltiazem on the uptake of cefpodoxime proxetil (CP). The study was aimed at establishing the impact of increased mesenteric blood flow due to calcium channel blockers on passive transport. Twelve volunteers were given CP (200 mg) orally in a crossover design. The absorption, disposition, and elimination parameters of cefpodoxime were compared among the following three treatment groups: CP alone, CP following oral administration of diltiazem (60 mg), or CP following oral administration of nifedipine (20 mg). No statistically significant difference in p

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Sica, Domenic A., and Todd W. B. Gehr. "Calcium-channel blockers and end-stage renal disease: pharmacokinetic and pharmacodynamic considerations." Current Opinion in Nephrology and Hypertension 12, no. 2 (2003): 123–31. http://dx.doi.org/10.1097/00041552-200303000-00001.

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Sica, Domenic A. "Calcium Channel Blocker Class Heterogeneity: Select Aspects of Pharmacokinetics and Pharmacodynamics." Journal of Clinical Hypertension 7 (April 2005): 21–26. http://dx.doi.org/10.1111/j.1524-6175.2006.04482.x.

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Hanafy, S., N. J. Dagenais, W. F. Dryden, and F. Jamali. "Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers." British Journal of Pharmacology 153, no. 1 (2008): 90–99. http://dx.doi.org/10.1038/sj.bjp.0707538.

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Dissertations / Theses on the topic "Calcium Channel Blockers – pharmacokinetics"

Al, Tafif Abdullah. "PREDICTION OF HUMAN SYSTEMIC, BIOLOGICALLY RELEVANT PHARMACOKINETIC PROPERTIES BASED ON PHYSICOCHEMICAL PROPERTIES OF CALCIUM CHANNEL BLOCKERS." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/2868.

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This research explored quantitative relationships (QSPKR) between different molecular descriptors and pertinent, systemic PK properties for 14 calcium channel blockers (CCB). Physicochemical properties (PC) such as molecular weight (MW), molar volume (MV), calculated logP (clogP), pKa, calculated logD7.4 (clogD), % ionized at pH 6.3 and pH 7.4, hydrogen bond donors (HBD), hydrogen bond acceptors (HBA), and number of rotatable bonds (nRot) were chosen as possible predictor variables for systemic PK properties for CCB, obtained from pertinent literature, assessing the PK of CCB after intravenous

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Waite, Robert Patrick. "The actions of calcium antagonists on systemic hemodynamics, blood flow distribution and venous tone of the rat." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26661.

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The purpose of my study was to determine and compare the effects of three calcium antagonists on systemic hemodynamics, ECG, blood flow distribution, tissue conductance and venous tone of the rat. The effects of a representative drug from Spedding's (1985) three subclasses of calcium antagonists on systemic hemodynamics, ECG, cardiac output and the distribution of blood flow were investigated by the microsphere technique in pentobarbital-anesthetized rats. The representative drugs were: I, nifedipine (12 and 35 µg/kg/min); II, verapamil (43 and 83 µg/kg/min) and III, flunarizine (174 and 27

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Rajab, M. "Investigating calcium channel blockers as antimalarials." Thesis, University of Salford, 2018. http://usir.salford.ac.uk/47791/.

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The rise in resistance to current antimalarial drugs has led researchers to consider drug repositioning as a quicker alternative for drug development and discovery. Preliminary drug repositioning screens carried out at the University of Salford identified calcium channel blockers (CCBs) as potential antimalarial agents. A growing body of evidence has demonstrated the importance of calcium within the <I>Plasmodium</I> life cycle. Studies have shown CCBs and calmodulin inhibitors to exhibit antimalarial activity. The research carried out in this project aims to evaluate the antimalarial efficacy

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Ting, Mo-sin Queenie. "The relationship between calcium channel blockers and endothelial inflammation /." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38297085.

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Ting, Mo-sin Queenie, and 丁慕仙. "The relationship between calcium channel blockers and endothelial inflammation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B45011485.

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Schwarzwald, Colin C. "Atrial and AV-nodal physiology in horses electrophysiologic and echocardiographic characterization and pharmacologic effects of diltiazem /." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1158079213.

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McNally, P. G. "The influence of calcium channel blockers on cyclosporin A nephrotoxicity." Thesis, University of Leicester, 1990. http://hdl.handle.net/2381/34162.

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Intrarenal vasoconstriction is a characteristic feature of cyclosporin A nephrotoxicity. This thesis investigates the effect of nifedipine, a dihydropyridine calcium channel blocker and potent renal vasodilator, on various aspects of experimental and clinical cyclosporin A nephrotoxicity. In the surgically intact spontaneously hypertensive rat (two-kidney model), short-term administration of cyclosporin A (14 days) induced a marked reduction in glomerular filtration rate and effective renal plasma flow, and an increase in renal vascular resistance. These changes were both reversible on stoppin

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Myrillas, Theofilos T. "Cellular mechanisms underlying the pathogenesis of cyclosporin A-induced gingival overgrowth." Thesis, Queen's University Belfast, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284391.

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Peterson, Blaise. "Molecular determinants of dihydropyridine binding on L-type calcium channels /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/6269.

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Wide-Swensson, Dag. "Hypertension in pregnancy effects of calcium channel blockade /." Lund : Dept. of Obstetrics and Gynecology, University of Lund, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39783426.html.

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Books on the topic "Calcium Channel Blockers – pharmacokinetics"

Lydtin, Helmut. Calcium antagonists: A critical review. Springer-Verlag, 1990.

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Calcium channel blockers. Birkhäuser Verlag, 2004.

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Godfraind, T. Calcium channel blockers. Birkhauser Verlag, 2003.

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Godfraind, Théophile. Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3.

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Sklar, Grant. A retrospective drug utilization review of the calcium channel blockers. Ottawa Civic Hospital, 1989.

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Calcium antagonists. Academic Press, 1988.

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Opie, Lionel H. Clinical use of calcium channel antagonist drugs. Kluwer Academic Publishers, 1989.

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Second generation of calcium antagonists. Springer-Verlag, 1991.

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Nayler, Winifred G. Calcium antagonists / Winifred G. Nayler. Academic, 1988.

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Japan-U.S.A. Symposium on Cardiovascular Drugs (1989 Kahuku, Hawaii). Recent advances in calcium channels and calcium antagonists: Proceedings of the Japan-U.S.A. Symposium on Cardiovascular Drugs. Edited by Yamada Kazuo and Shibata Shoji. Pergamon Press, 1990.

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Book chapters on the topic "Calcium Channel Blockers – pharmacokinetics"

Ong, Peter, and Udo Sechtem. "Calcium Channel Blockers." In Pharmacological Treatment of Chronic Stable Angina Pectoris. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17332-0_4.

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Özkaya, Esen, and Kurtuluş Didem Yazganoğlu. "Calcium Channel Blockers." In Adverse Cutaneous Drug Reactions to Cardiovascular Drugs. Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-6536-1_8.

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Ertel, Eric, and Théophile Godfraind. "Calcium channel blockers and calcium channels." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_2.

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Godfraind, Théophile. "Historical perspective: from early steps on calcium research to the identification of calcium antagonist prototypes and of the signaling functions of Ca2+." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_1.

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Godfraind, Théophile. "Beyond the cardiovascular system." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_10.

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Godfraind, Théophile. "The action of calcium antagonists on Ca2+ movements in isolated vessels." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_3.

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Godfraind, Théophile. "The tissue selectivity of calcium antagonists." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_4.

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Godfraind, Théophile. "Acute haemodynamic effects of calcium channel blockers." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_5.

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Godfraind, Théophile. "Calcium channels and regulation of vascular tone in hypertension." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_6.

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Godfraind, Théophile. "Long-term effects of calcium antagonists." In Calcium Channel Blockers. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7859-3_7.

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Conference papers on the topic "Calcium Channel Blockers – pharmacokinetics"

Patil, Vaishali, and Neeraj Masand. "Applications of Structure Based Drug Design Approaches towards Design and Development of Calcium Channel Blockers." In MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition. MDPI, 2017. http://dx.doi.org/10.3390/mol2net-03-05051.

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Nerbass, Flávia B., Rodrigo P. Pedrosa, Pedro R. Genta, Luciano F. Drager, and Geraldo Lorenzi-Filho. "Calcium Channel Blockers Are Associated With Total Sleep Time Reduction in Hypertensive Patients With Obstructive Sleep Apnea." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3668.

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Piloto, Bruna, Caio Fernandes, Carlos Jardim, et al. "Loss of response to calcium channel blockers after long-term follow up in idiopathic pulmonary arterial hypertension." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1466.

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Li, Wei, Zhijun Liu, Jennifer Xavier, and Hong-Gang Wang. "Abstract 121: Identification and characterization of calcium channel blockers as inhibitors of YAP/TAZ and glioblastoma cells." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-121.

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Tsuzuki, R., S. Yamawaki, S. Soeda, et al. "An Inhibitory Effects of Calcium Channel Blockers on Deteriorations of Forced Expiratory Volume in One Second in Asthma." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6110.

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Caton, M., I. Mark, A. Baker, et al. "E-060 Endovascular treatment for intracranial giant cell arteritis with angioplasty, stenting, and intra-arterial calcium channel blockers." In SNIS 18TH ANNUAL MEETING. BMJ Publishing Group Ltd., 2021. http://dx.doi.org/10.1136/neurintsurg-2021-snis.155.

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Rafeeque, Ameena, and Mohammed Fasihul Alam. "The effect of Renin Angiotensin System Blockers versus Calcium Channel Blockers on Progression towards Hypertensive Chronic Kidney Disease: A comprehensive systematic review based on Randomized Controlled Trials." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0162.

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Background: Decline in estimated Glomerular filtration rate (eGFR) is associated with further progression of chronic kidney disease. Evidence suggests that Renin Angiotensin System blockers (RAS), which can be angiotensin-receptor blockers (ARBs) or Angiotensin converting enzymes Inhibitors (ACEIs), have reno- protective effect, but results are variable. Similarly, effects of Calcium channel blockers (CCBs) are shown to have a role in protecting renal function but differ across studies. Hence, the relative effect of ARBs or ACEIs as well as CCBs, and their administration as monotherapy, remain

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Tie, H., H. Welp, S. Martens, J. Sindermann, and S. Martens. "Calcium-Channel Blockers (Amlodipine) Therapy Is Associated with Improved Survival in Patients after Continuous-Flow Left Ventricular Assist Devices." In 50th Annual Meeting of the German Society for Thoracic and Cardiovascular Surgery (DGTHG). Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1725651.

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Rademaker, M., R. H. Meyrick Thomas, J. D. Kirby, and I. B. Kovaos. "EFFECT OF THE CALCIUM CHANNEL BLOCKER, NIFEDIPINE, ON HAEMOSTASIS, CLOTTING, AND THROMBOLYSIS EX VIVO." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643436.

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Nifedipine, as other calcium channel blockers, has been shown to inhibit platelet aggregation induced by various agonists in vitro. The therapeutic relevance of these findings are, however, questionable, as in vitro inhibition of platelet function occurs at plasma concentrations of nifedipine in excess of 50 uM, while the peak plasma concentration following a single 10 mg oral dose of nifedipine is only 0.2 uM. We have used the Haemostatometer, to assess the effect of nifedipine on haemostasis ex vivo. This instrument allows quantitative assessment of haemostasis by monitoring the pattern of h

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K., Saniya, Patil B. G., Madhavrao C., Prakash K. G., and Mythili Bai K. "Effect of T-Type of Calcium Channel Blockers on Behavioral, Biochemical, Immunohistochemical, Oxidative, and Histopathological Parameters in Chemically Induced Seizure Tests in Wistar Albino Rats." In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694892.

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Reports on the topic "Calcium Channel Blockers – pharmacokinetics"

Calcium channel blockers are useful in managing Raynaud’s phenomenon. National Institute for Health Research, 2018. http://dx.doi.org/10.3310/signal-000556.

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