Academic literature on the topic 'CD271 Marker'

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Journal articles on the topic "CD271 Marker"

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Peng, Qiuyue, Martyna Duda, Guoqiang Ren, et al. "Multiplex Analysis of Adipose-Derived Stem Cell (ASC) Immunophenotype Adaption to In Vitro Expansion." Cells 10, no. 2 (2021): 218. http://dx.doi.org/10.3390/cells10020218.

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In order to enhance the therapeutic potential, it is important that sufficient knowledge regarding the dynamic changes of adipose-derived stem cell (ASC) immunophenotypical and biological properties during in vitro growth is available. Consequently, we embarked on a study to follow the evolution of highly defined cell subsets from three unrelated donors in the course of eight passages on tissue culture polystyrene. The co-expression patterns were defined by panels encompassing seven and five cell surface markers, including CD34, CD146, CD166, CD200, CD248, CD271, and CD274 and CD29, CD31, CD36
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Liang, L., Ludivine Coudière Morrison, Nazanin Tatari, et al. "15 CD271/p75NTR is a novel diagnostic marker, prognostic indicator and therapeutic target for SHH medulloblastoma." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 45, S3 (2018): S12—S13. http://dx.doi.org/10.1017/cjn.2018.294.

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The extensive heterogeneity both between and within the medulloblastoma (MB) subgroups underscores a critical need for variant-specific biomarkers and therapeutic strategies. We previously identified a role for the CD271/p75 neurotrophin receptor (p75NTR) in regulating stem/progenitor cells in the SHH MB subgroup. Here, we demonstrate the utility of CD271 as a novel diagnostic and prognostic marker for SHH MB using immunohistochemical analysis as well as transcriptome data across 763 primary tumors. Characterization of CD271+ and CD271- cells by RNA sequencing revealed that these two subpopula
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Tormin, Ariane, Jan Claas Brune, Stuart Walsh, Johan Richter, Xiaolong Fan, and Stefan Scheding. "Human Primary Mensenchymal Stromal Progenitor Cells Are Highly Enriched in Both, the CD271+/CD146+ and CD271+/CD146− Bone Marrow Population with the Latter Acquiring CD146 Expression upon Culture in-Vitro." Blood 112, no. 11 (2008): 2422. http://dx.doi.org/10.1182/blood.v112.11.2422.2422.

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Abstract Culture-derived mesenchymal stromal cells (MSC), which are attractive candidates for clinical cell therapy approaches, arise from primary MSC progenitor/stem cells in the bone marrow. Recently, several groups have reported markers (CD271, CD146, GD2, SSEA4, etc.) that allowed for an enrichment of CFU-F, i.e. primary MSC progenitors. However, the exact phenotype of the bona fide mesenchymal stem/progenitor cells has not yet not been sufficiently defined. We therefore aimed to investigate primary MSC in bone marrow subpopulations defined by the expression of CD271 and CD146, as both mar
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Peng, Qiuyue, Guoqiang Ren, Zongzhe Xuan, et al. "Distinct Dominant Lineage from In Vitro Expanded Adipose-Derived Stem Cells (ASCs) Exhibits Enhanced Wound Healing Properties." Cells 11, no. 7 (2022): 1236. http://dx.doi.org/10.3390/cells11071236.

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It has been suggested that immunophenotypically defined lineages within the in vitro expanded adipose-derived stem cell (ASC) may play a beneficial role from the perspective of a personalized intervention. Therefore, to better understand the implications of different surface marker profiles for the functionality, we set out to examine the evolution of ASC-variants based on the co-expression of five bright or eight dim epitopes. At passages P1, P4, and P8, the co-localization of five bright markers (CD73, CD90, CD105, CD166, and CD201), or eight dim markers (CD34, CD36, CD200, CD248, CD271, CD2
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Tormin, Ariane, Ou Li, Stuart Walsh, Mats Ehinger, Jan Claas Brune, and Stefan Scheding. "CD146 Expression in Primary Bone Marrow MSC Progenitor/Stem Cells Is Dependent On Their In Vivo Location." Blood 114, no. 22 (2009): 251. http://dx.doi.org/10.1182/blood.v114.22.251.251.

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Abstract Abstract 251 Primary MSC progenitor/stem cells (MSC-PC/SC) represent only a minute fraction of the bone marrow cells and they give rise to the well-known mesenchymal stromal cells (MSC) in culture. In vivo, MSC-PC/SC are probable constituents of the hematopoietic stem cell niche, thus playing an important role in supporting, maintaining and controlling hematopoiesis. Enrichment of primary MSC progenitors, i.e. CFU-F, has been recently reported based on expression of surface markers such as CD271, CD146, GD2, SSEA4, etc. Based on the expression of CD271 and CD146 on primary MSC (Quiric
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Elkashty, Osama A., Ghada Abu Elghanam, Xinyun Su, Younan Liu, Peter J. Chauvin, and Simon D. Tran. "Cancer stem cells enrichment with surface markers CD271 and CD44 in human head and neck squamous cell carcinomas." Carcinogenesis 41, no. 4 (2019): 458–66. http://dx.doi.org/10.1093/carcin/bgz182.

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Abstract Head and neck squamous cell carcinoma (HNSCC) has a poor 5-year survival rate of 50%. One potential reason for treatment failure is the presence of cancer stem cells (CSCs). Several cell markers, particularly CD44, have been used to isolate CSCs. However, isolating a pure population of CSC in HNSCC still remains a challenging task. Recent findings show that normal oral stem cells were isolated using CD271 as a marker. Thus, we investigated the combined use of CD271 and CD44 to isolate an enriched subpopulation of CSCs, followed by their characterization in vitro, in vivo, and in patie
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Bellagamba, Bruno Corrêa, Patrícia Bencke Grudzinski, Pedro Bins Ely, Paulo de Jesus Hartmann Nader, Nance Beyer Nardi, and Lindolfo da Silva Meirelles. "Induction of Expression of CD271 and CD34 in Mesenchymal Stromal Cells Cultured as Spheroids." Stem Cells International 2018 (July 31, 2018): 1–14. http://dx.doi.org/10.1155/2018/7357213.

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Cultured mesenchymal stromal cells (MSCs) are cells that can be used for tissue engineering or cell therapies owing to their multipotency and ability to secrete immunomodulatory and trophic molecules. Several studies suggest that MSCs can become pericytes when cocultured with endothelial cells (ECs) but failed to use pericyte markers not already expressed by MSCs. We hypothesized ECs could instruct MSCs to express the molecules CD271 or CD34, which are expressed by pericytes in situ but not by MSCs. CD271 is a marker of especial interest because it is associated with multipotency, a characteri
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Han, Bo La, Lan Zhou, Qiunong Guan, Gerald da Roza, Hao Wang, and Caigan Du. "In VitroExpansion and Characterization of Mesenchymal Stromal Cells from Peritoneal Dialysis Effluent in a Human Protein Medium." Stem Cells International 2018 (October 3, 2018): 1–10. http://dx.doi.org/10.1155/2018/5868745.

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The therapeutic potential of mesenchymal stromal cells (MSCs) from various tissue origins have extensively been explored in both experimental and clinical studies, and peritoneal dialysis effluent-derived MSC (pMSC) may be an easily obtainable MSC source for clinical applications. In this study, we expanded and characterized the pMSCs after expansion in a human protein culture medium. The pMSCs were expanded in plastic dishes with the human protein medium. MSC marker expression was examined by flow cytometry. Spherical formation was tested by hanging drop method, and osteogenic, adipogenic, an
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Jiang, Ying, Jennifer Powers, George F. Muschler, and Jaroslaw P. Maciejewski. "Expression of CD271 in Normal and Malignant Hematopoietic Progenitor and Stem Cells." Blood 108, no. 11 (2006): 4271. http://dx.doi.org/10.1182/blood.v108.11.4271.4271.

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Abstract The relationship between mesenchymal (MSC) and hematopoietic stem cells (HSC) involves close interaction in the marrow microenvironment. They also may share certain phenotypic features and even possibly a multipotent common precursor. CD271 (also known as LNGFR, p75NTR) has been reported to be a suitable marker of resting primitive MSCs. CD271 and its ligands, neurotrophins (NTs, e.g. nerve growth factor) also play important roles in hematopoiesis, such as enhancement of colony formation by human bone marrow progenitor cells. Dysregulated expression or mutations of NT receptors were a
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Cheli, Yann, Vanessa F. Bonnazi, Arnaud Jacquel, et al. "CD271 is an imperfect marker for melanoma initiating cells." Oncotarget 5, no. 14 (2014): 5272–83. http://dx.doi.org/10.18632/oncotarget.1967.

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Dissertations / Theses on the topic "CD271 Marker"

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Atlas, Ann. "Immunological and virological response to antiretroviral treatment (art) in patients infected with different HIV-1genetic subtypes /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-645-X/.

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Knosalla, Marcel [Verfasser], Undine [Akademischer Betreuer] Lippert, Christine [Akademischer Betreuer] Neumann, Martin [Akademischer Betreuer] Oppermann, and Patricia [Akademischer Betreuer] Virsik-köpp. "Expression der kostimulatorischen Moleküle ILA (CD137) und ICOS (CD278) sowie ihrer Liganden auf Mastzellen und T-Zellen der Haut von Patienten mit Psoriasis vulgaris / Marcel Knosalla. Gutachter: Christine Neumann ; Martin Oppermann ; Patricia Virsik-Köpp. Betreuer: Undine, Lippert." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2011. http://d-nb.info/1042733724/34.

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Book chapters on the topic "CD271 Marker"

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Daniela Holthausen Perico, Maria, and Renata Kalfeltz. "T-Cell Receptor: from T-cell function to T-cell clonality." In Biology of T Cells in Health and Disease [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1004631.

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Evaluation of T cell clonality has been costly and/or time-consuming. The analysis of TCR β-chain constant region 1 (TRBC1) provides a simplified immunophenotypic assessment of T-cell clonality. Furthermore, due to the high variability of T-cell populations, there is a need for reliable and robust panels to sort normally from pathological T-cells. The CD27 and CD45RA phenotypic profiling strategy associated with the evaluation of TCRCBeta1 in the same cytometry tube is able to separate normal T Cell populations from clonal populations, gating clusters of cells according to their CD45RA x CD27
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Conference papers on the topic "CD271 Marker"

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Xiong, Wei, Peirong Hu, Michael Wagner, et al. "337 Dual role of CD276 as target antigen and putative activation marker in CD276-redirected CAR T cells for the treatment of solid tumors." In SITC 39th Annual Meeting (SITC 2024) Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/jitc-2024-sitc2024.0337.

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Khoogar, Roxane, and Peter Houghton. "Abstract 2074: Single-cell RNA-seq reveals heterogeneity for stem cell markers, LRG5 and CD271 to predict a subpopulation in Ewing sarcoma cells with lower levels of BRAF." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2074.

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