Academic literature on the topic 'Cellular Delivery - Anionic Nanoparticles'

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Journal articles on the topic "Cellular Delivery - Anionic Nanoparticles"

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Maity, Amit Ranjan, and Nikhil R. Jana. "Chitosan−Cholesterol-Based Cellular Delivery of Anionic Nanoparticles." Journal of Physical Chemistry C 115, no. 1 (2010): 137–44. http://dx.doi.org/10.1021/jp108828c.

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Xu, Zhi Ping, and G. Q. (Max) Lu. "Layered double hydroxide nanomaterials as potential cellular drug delivery agents." Pure and Applied Chemistry 78, no. 9 (2006): 1771–79. http://dx.doi.org/10.1351/pac200678091771.

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This paper briefly reviews the recent progress in using layered double hydroxide (LDH) nanomaterials as cellular delivery agents. The advantages of LDHs as cellular delivery agents are summarized, and the processes of interaction/de-intercalation of anionic drugs (genes) into/from LDH nanoparticles are discussed. Then the cellular delivery of LDH-drug (gene) nanohybrids and subsequent intracellular processes are presumably proposed. At the end, some challenges and remarks for efficient delivery of drugs (genes) via LDH nanoparticles are provided to the best of our knowledge.
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Choi, Soo-Jin, Jae-Min Oh, Taeun Park, and Jin-Ho Choy. "Cellular Toxicity of Inorganic Hydroxide Nanoparticles." Journal of Nanoscience and Nanotechnology 7, no. 11 (2007): 4017–20. http://dx.doi.org/10.1166/jnn.2007.085.

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Layered double hydroxides (LDHs), anionic clays, have attracted increasing interest as nanovehicles for delivering genes, drugs, and bio-active molecules into cells. However, no attempts have been made to evaluate the potential undesirable effects of LDH nanoparticles. The cytotoxicity of LDHs with different chemical compositions (ZnAl- and MgAl-LDH) was systematically evaluated in various cell types, such as human normal cells, carcinoma cells, and red blood cells, by measuring cell viability, cell proliferation, membrane damage, and hemolytic effect. No significant cytotoxic effects could be
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Choi, Soo-Jin, Jae-Min Oh, Taeun Park, and Jin-Ho Choy. "Cellular Toxicity of Inorganic Hydroxide Nanoparticles." Journal of Nanoscience and Nanotechnology 7, no. 11 (2007): 4017–20. http://dx.doi.org/10.1166/jnn.2007.18081.

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Layered double hydroxides (LDHs), anionic clays, have attracted increasing interest as nanovehicles for delivering genes, drugs, and bio-active molecules into cells. However, no attempts have been made to evaluate the potential undesirable effects of LDH nanoparticles. The cytotoxicity of LDHs with different chemical compositions (ZnAl- and MgAl-LDH) was systematically evaluated in various cell types, such as human normal cells, carcinoma cells, and red blood cells, by measuring cell viability, cell proliferation, membrane damage, and hemolytic effect. No significant cytotoxic effects could be
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Berger, Eric, Dalibor Breznan, Sandra Stals, et al. "Cytotoxicity assessment, inflammatory properties, and cellular uptake of Neutraplex lipid-based nanoparticles in THP-1 monocyte-derived macrophages." Nanobiomedicine 4 (January 1, 2017): 184954351774625. http://dx.doi.org/10.1177/1849543517746259.

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Current antiretroviral drugs used to prevent or treat human immunodeficiency virus type 1 (HIV-1) infection are not able to eliminate the virus within tissues or cells where HIV establishes reservoirs. Hence, there is an urgent need to develop targeted delivery systems to enhance drug concentrations in these viral sanctuary sites. Macrophages are key players in HIV infection and contribute significantly to the cellular reservoirs of HIV because the virus can survive for prolonged periods in these cells. In the present work, we investigated the potential of the lipid-based Neutraplex nanosystem
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Tsai, Li-Hui, Chia-Hsiang Yen, Hao-Ying Hsieh, and Tai-Horng Young. "Doxorubicin Loaded PLGA Nanoparticle with Cationic/Anionic Polyelectrolyte Decoration: Characterization, and Its Therapeutic Potency." Polymers 13, no. 5 (2021): 693. http://dx.doi.org/10.3390/polym13050693.

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Optimized Doxorubicin hydrochloride (DOX) loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles (DPN) were prepared by controlling the water/oil distribution of DOX at different pH solutions and controlling the electrostatic interaction between DOX and different terminated-end PLGAs. Furthermore, cationic polyethylenimine (PEI) and anionic poly (acrylic acid) (PAA) were alternately deposited on DPN surface to form PEI-DPN (IDPN) and PAA-PEI-DPN (AIDPN) to enhance cancer therapy potency. Compared to DPN, IDPN exhibited a slower release rate in physiological conditions but PEI was demonstrat
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Rotan, Olga, Katharina N. Severin, Simon Pöpsel, et al. "Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticles." Beilstein Journal of Nanotechnology 8 (February 7, 2017): 381–93. http://dx.doi.org/10.3762/bjnano.8.40.

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The efficient intracellular delivery of (bio)molecules into living cells remains a challenge in biomedicine. Many biomolecules and synthetic drugs are not able to cross the cell membrane, which is a problem if an intracellular mode of action is desired, for example, with a nuclear receptor. Calcium phosphate nanoparticles can serve as carriers for small and large biomolecules as well as for synthetic compounds. The nanoparticles were prepared and colloidally stabilized with either polyethyleneimine (PEI; cationic nanoparticles) or carboxymethyl cellulose (CMC; anionic nanoparticles) and loaded
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Uto, Tomofumi, Takami Akagi, Mitsuru Akashi, and Masanori Baba. "Induction of Potent Adaptive Immunity by the Novel Polyion Complex Nanoparticles." Clinical and Vaccine Immunology 22, no. 5 (2015): 578–85. http://dx.doi.org/10.1128/cvi.00080-15.

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ABSTRACTThe development of effective and simple methods of vaccine preparation is desired for the prophylaxis and treatment of a variety of infectious diseases and cancers. We have created novel polyion complex (PIC) nanoparticles (NPs) composed of amphiphilic anionic biodegradable poly(γ-glutamic acid) (γ-PGA) and cationic polymers as a vaccine adjuvant. PIC NPs can be prepared by mixing γ-PGA-graft-l-phenylalanine ethylester (γ-PGA-Phe) polymer with cationic polymer in phosphate-buffered saline. We examined the efficacy of PIC NPs for antigen delivery and immunostimulatory activityin vitroan
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Tukova, Anastasiia, Inga Christine Kuschnerus, Alfonso Garcia-Bennett, Yuling Wang, and Alison Rodger. "Gold Nanostars with Reduced Fouling Facilitate Small Molecule Detection in the Presence of Protein." Nanomaterials 11, no. 10 (2021): 2565. http://dx.doi.org/10.3390/nano11102565.

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Gold nanoparticles have the potential to be used in biomedical applications from diagnostics to drug delivery. However, interactions of gold nanoparticles with different biomolecules in the cellular environment result in the formation of a “protein corona”—a layer of protein formed around a nanoparticle, which induces changes in the properties of nanoparticles. In this work we developed methods to reproducibly synthesize spheroidal and star-shaped gold nanoparticles, and carried out a physico-chemical characterization of synthesized anionic gold nanospheroids and gold nanostars through transmi
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Cotta, Karishma Berta, Sarika Mehra, and Rajdip Bandyopadhyaya. "pH-driven enhancement of anti-tubercular drug loading on iron oxide nanoparticles for drug delivery in macrophages." Beilstein Journal of Nanotechnology 12 (October 7, 2021): 1127–39. http://dx.doi.org/10.3762/bjnano.12.84.

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Nanoparticle deployment in drug delivery is contingent upon controlled drug loading and a desired release profile, with simultaneous biocompatibility and cellular targeting. Iron oxide nanoparticles (IONPs), being biocompatible, are used as drug carriers. However, to prevent aggregation of bare IONPs, they are coated with stabilizing agents. We hypothesize that, zwitterionic drugs like norfloxacin (NOR, a fluoroquinolone) can manifest dual functionality – nanoparticle stabilization and antibiotic activity, eliminating the need of a separate stabilizing agent. Since these drugs have different c
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Dissertations / Theses on the topic "Cellular Delivery - Anionic Nanoparticles"

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Zhang, Mengzi. "DEVELOPMENTS OF LIPID-BASED NANOPARTICLES FOR THERAPEUTIC DRUG DELIVERY." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1417025932.

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Mendez, Eladio A. "Conjugated Polymer Nanoparticles for Biological Labeling and Delivery." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/1837.

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Cancer remains one of the world’s most devastating diseases, with more than 10 million new cases every year. However, traditional treatments have proven insufficient for successful medical management of cancer due to the chemotherapeutics’ difficulty in achieving therapeutic concentrations at the target site, non-specific cytotoxicity to normal tissues, and limited systemic circulation lifetime. Although, a concerted effort has been placed in developing and successfully employing nanoparticle(NP)-based drug delivery vehicles successfully mitigate the physiochemical and pharmacological limitati
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Khan, Md Arif. "NANOHARVESTING AND DELIVERY OF BIOACTIVE MATERIALS USING ENGINEERED SILICA NANOPARTICLES." UKnowledge, 2019. https://uknowledge.uky.edu/cme_etds/110.

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Mesoporous silica nanoparticles (MSNPs) possess large surface areas and ample pore space that can be readily modified with specific functional groups for targeted binding of bioactive materials to be transported through cellular barriers. Engineered silica nanoparticles (ESNP) have been used extensively to deliver bio-active materials to target intracellular sites, including as non-viral vectors for nucleic acid (DNA/RNA) delivery such as for siRNA induced interference. The reverse process guided by the same principles is called “nanoharvesting”, where valuable biomolecules are carried out and
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Duong, Anthony David. "Electrohydrodynamic Spray Fabrication of Microparticles and Nanoparticles for Use as Biomedical Delivery Vehicles." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1376913508.

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Li, Miao [Verfasser], and Jochen [Akademischer Betreuer] Feldmann. "Optical cellular delivery and intracellular sensing of fN forces using gold nanoparticles / Miao Li. Betreuer: Jochen Feldmann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1110748965/34.

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Graf, Franziska. "DNA Origami Nanoparticles for Cell Delivery: The Effect of Shape and Surface Functionalization on Cell Internalization." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10259.

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An outstanding challenge in modern medicine is the safe and efficient delivery of drugs. One approach to improve drug delivery yield and increase specificity towards diseased cells, is to employ a drug carrier to facilitate transport. Promising steps towards developing such a carrier have been taken by the nascent field of nanomedicine: nanometer-sized particles designed to evade premature excretion, non-specific absorption, and the body’s immune response, can reduce undesired drug loss, while also increasing specific drug uptake into diseased cells through targeting surface modifications. How
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Nitin, Nitin. "Optical and MR Molecular Imaging Probes and Peptide-based Cellular Delivery for RNA Detection in Living Cells." Diss., Available online, Georgia Institute of Technology, 2005, 2005. http://etd.gatech.edu/theses/available/etd-08102005-120350/.

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Thesis (Ph. D.)--Biomedical Engineering, Georgia Institute of Technology, 2006.<br>Dr. X. Hu, Committee Member ; Dr. Al Merrill, Committee Member ; Dr. Niren Murthy, Committee Member ; Dr. Gang Bao, Committee Chair ; Dr. Nicholas Hud, Committee Member. Includes bibliographical references.
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Huang, Xiaomeng. "Targeted Delivery of MicroRNAs by Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1405095496.

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Liebsch, Nicole Verfasser], and Claus-Michael [Akademischer Betreuer] [Lehr. "Cationic polymer coating of PLGA nanoparticles for enabling cellular delivery of siRNA / Nicole Liebsch ; Betreuer: Claus-Michael Lehr." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:291-scidok-ds-271196.

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Liebsch, Nicole [Verfasser], and Claus-Michael [Akademischer Betreuer] Lehr. "Cationic polymer coating of PLGA nanoparticles for enabling cellular delivery of siRNA / Nicole Liebsch ; Betreuer: Claus-Michael Lehr." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2017. http://d-nb.info/1155760522/34.

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Books on the topic "Cellular Delivery - Anionic Nanoparticles"

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Akashi, Misturu, Takami Akagi, and Michiya Matsusaki. Engineered Cell Manipulation for Biomedical Application. Springer, 2016.

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Akashi, Misturu, Takami Akagi, and Michiya Matsusaki. Engineered Cell Manipulation for Biomedical Application. Springer, 2014.

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Akashi, Misturu, Takami Akagi, and Michiya Matsusaki. Engineered Cell Manipulation for Biomedical Application. Springer Japan, 2014.

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Book chapters on the topic "Cellular Delivery - Anionic Nanoparticles"

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Barin, Gozde, Yakup Gultekin, Pezik, Naile Ozturk, Asli Kara, and Imran Vural. "Cellular Uptake and Transcytosis." In Drug Delivery with Targeted Nanoparticles. Jenny Stanford Publishing, 2021. http://dx.doi.org/10.1201/9781003164739-10.

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Kumari, Avnesh, Rubbel Singla, Anika Guliani, Amitabha Acharya, and Sudesh Kumar Yadav. "Cellular Response of Therapeutic Nanoparticles." In Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-0818-4_7.

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Nagelli, Christopher V., Christopher H. Evans, and Rodolfo E. De la Vega. "Gene Delivery to Chondrocytes." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-25588-5_7.

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AbstractDelivering genes to chondrocytes offers new possibilities both clinically, for treating conditions that affect cartilage, and in the laboratory, for studying the biology of chondrocytes. Advances in gene therapy have created a number of different viral and non-viral vectors for this purpose. These vectors may be deployed in an ex vivo fashion, where chondrocytes are genetically modified outside the body, or by in vivo delivery where the vector is introduced directly into the body; in the case of articular and meniscal cartilage in vivo delivery is typically by intra-articular injection
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Smirnov, Pierre. "Cellular Magnetic Resonance Imaging Using Superparamagnetic Anionic Iron Oxide Nanoparticles: Applications to In Vivo Trafficking of Lymphocytes and Cell-Based Anticancer Therapy." In Methods in Molecular Biology™. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-530-9_19.

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Singh, Vandana, Ankush Verma, Amit Pratap Singh Chouhan, Rahul Saxena, Sanjana Koranga, and Takreem Husain. "Safety and Toxicity of Nanomaterials in Medicine." In Cutting-Edge Applications of Nanomaterials in Biomedical Sciences. IGI Global, 2023. http://dx.doi.org/10.4018/979-8-3693-0448-8.ch018.

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Nanomaterials' unique physicochemical features make them suitable for biological applications such medication delivery, imaging, and tissue engineering. However, there is growing concern regarding their safety and toxicity due to their small size and high surface area, which can result in unanticipated interactions with biological systems. Studies have demonstrated that cationic nanoparticles exhibit a propensity to interact with cellular membranes and elicit oxidative stress, while anionic nanoparticles have a tendency to accumulate within lysosomes and trigger inflammatory responses. Numerou
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"In Vitro Characterization of Nanoparticle Cellular Interaction." In Drug Delivery Nanoparticles Formulation and Characterization. CRC Press, 2016. http://dx.doi.org/10.3109/9781420078053-15.

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Akturk, Omer, and Bengi Yilmaz. "Cellular interactions and design principles of glyco-gold nanoparticles for drug delivery applications." In Gold Nanoparticles for Drug Delivery. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-19061-2.00012-2.

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"Animal and Cellular Models for Use in Nanoparticles Safety Study." In Nanomedicine in Drug Delivery. CRC Press, 2013. http://dx.doi.org/10.1201/b14802-16.

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Macedo, Letícia Bueno, Cristiane Franco Codevilla, Daniela Mathes, Bianca Costa Maia, Clarice Madalena Bueno Rolim, and Daniele Rubert Nogueira-Librelotto. "Biofate and cellular interactions of PLGA nanoparticles." In Poly(Lactic-Co-glycolic Acid) (PLGA) Nanoparticles for Drug Delivery. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-323-91215-0.00003-0.

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Morán, M. C., and M. Ferrari. "DNA Particles." In Soft Nanoparticles for Biomedical Applications, 2nd ed. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781837675203-00226.

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Inspired by the intricate designs of biological systems, soft matter has emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled advantages in therapeutic delivery, including therapeutic-grade DNA molecules. These systems are lauded for their targeted delivery, minimized side effects, and enhanced therapeutic outcomes encompassing platforms such as polymeric nanoparticles and micelles, dendrimers, liposomes, solid lipid nanoparticles, protein-based nanoparticles, and hydrogels. In this chapter, the recent advances in these colloidal delivery carriers are reviewed and the st
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Conference papers on the topic "Cellular Delivery - Anionic Nanoparticles"

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Sangtani, Ajmeeta, Russ Algar, Guillermo Lasarte-Aragonés, et al. "Nanoparticle bioconjugate for controlled cellular delivery of doxorubicin." In Colloidal Nanoparticles for Biomedical Applications XIII, edited by Xing-Jie Liang, Wolfgang J. Parak, and Marek Osiński. SPIE, 2018. http://dx.doi.org/10.1117/12.2290031.

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Nieto-Chaupis, Huber. "Modeling the Electrodynamics of Cellular Uptake of Nanoparticles at Drug Delivery Strategies." In 2022 IEEE 22nd International Conference on Bioinformatics and Bioengineering (BIBE). IEEE, 2022. http://dx.doi.org/10.1109/bibe55377.2022.00077.

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Yum, Kyungsuk, Sungsoo Na, Yang Xiang, Ning Wang, and Min-Feng Yu. "Nanomechanochemical Delivery of Nanoparticles for Nanomechanics Inside Living Cells." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13039.

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Studying biological processes and mechanics in living cells is challenging but highly rewarding. Recent advances in experimental techniques have provided numerous ways to investigate cellular processes and mechanics of living cells. However, most of existing techniques for biomechanics are limited to experiments outside or on the membrane of cells, due to the difficulties in physically accessing the interior of living cells. On the other hand, nanomaterials, such as fluorescent quantum dots (QDs) and magnetic nanoparticles, have shown great promise to overcome such limitations due to their sma
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Liu, Xuan, Zhaoxiong Wan, Yuanwei Zhang, and Yuwei Liu. "Optically computed phase microscopy to assess cellular uptake of lipid nanoparticles." In CLEO: Applications and Technology. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_at.2022.atu5i.6.

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We developed a novel optically computed phase microscopy (OCPM) system, for depth-resolved phase imaging. We used OCPM to assess cellular uptake of lipid nanoparticles (LNPs), for the optimization of drug delivery systems based on LNPs.
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Mulvana, Helen, Julien Reboud, Maria de Scrilli, and Catherine Berry. "Uptake and cellular recovery mechanisms in microbubble-enhanced ultrasound delivery of nanoparticles for cancer therapy." In 2015 IEEE International Ultrasonics Symposium (IUS). IEEE, 2015. http://dx.doi.org/10.1109/ultsym.2015.0403.

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Zhang, Wujie, Jianhua Rong, Qian Wang, and Xiaoming He. "Synthesis, Cellular Uptake, and Cytotoxicity of a Thermally Responsive Nanocapsule." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206872.

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Recently, polymeric nanoparticles have attracted tremendous interests as a useful tool to encapsulate therapeutic drugs, genes, and proteins for their controlled and sustained delivery. Among them, polymeric hydrogel nanoparticles with thermal and/or pH responsiveness have attracted particular attention [1]. Trehalose, a non-reducing disaccharide of glucose, has been demonstrated to be a potent, nontoxic bioprotectant for stabilizing lipids, proteins, viruses, and blood cells at cryogenic and particularly, ambient temperatures (i.e., cryo and lyopreservation) [2]. However, intracellular delive
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Ibarra, Luis Exequiel, Lucia Beaugé, Carlos Chesta, Viviana Alicia Rivarola, and Rodrigo Palacios. "Exploiting cellular delivery of conjugated polymer nanoparticles for improved photodynamic therapy in a 3D glioblastoma model." In 17th International Photodynamic Association World Congress, edited by Tayyaba Hasan. SPIE, 2019. http://dx.doi.org/10.1117/12.2526763.

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Afadzi, Mercy, Siv Eggen, Yrr Morch, et al. "Multifunctional nanoparticles for drug delivery and imaging: Effect of ultrasound on cellular uptake and tumor tissue distribution." In 2012 IEEE International Ultrasonics Symposium. IEEE, 2012. http://dx.doi.org/10.1109/ultsym.2012.0104.

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Rahman, Mohammad Aminur, Pengfei Wang, Dongsheng Wang, et al. "Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-187.

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Lian, Xizhen, Alfredo Erazo-Oliveras, Hong-Cai Zhou, and Jean-Philippe Pellois. "Delivery of nanoparticles inside the cytosol of live cells for the monitoring of cellular processes (Conference Presentation)." In Advances in Photonics of Quantum Computing, Memory, and Communication XI, edited by Zameer U. Hasan, Philip R. Hemmer, Alan L. Migdall, and Alan E. Craig. SPIE, 2018. http://dx.doi.org/10.1117/12.2300544.

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Reports on the topic "Cellular Delivery - Anionic Nanoparticles"

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Noel, Erika, Giulia Mattana, and Anthony McGoron. A Comparative Analysis of Nanoparticle Sizing Techniques for Enhanced Drug Delivery Applications. Florida International University, 2025. https://doi.org/10.25148/fiuurj.3.1.5.

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Nanoparticle-based drug delivery systems hold promise for improving therapeutic efficacy and targeting precision. However, a critical challenge in their development is ensuring size stability, as particle size directly influences biodistribution, cellular uptake, and drug release profiles. This study establishes a streamlined methodology to assess nanoparticle size consistency by comparing three widely used characterization techniques: Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM), and Nanoparticle Tracking Analysis (NTA). Two types of nanoparticles were analyzed: 100
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