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Relevant bibliographies by topics / Chloroquine

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Academic literature on the topic 'Chloroquine'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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Journal articles on the topic "Chloroquine"

1

Zdun, Sylwia, Klaudia Walczak, Weronika Gaweł, et al. "Side effects of long-term treatment with chloroquine for rheumatoid arthritis - a review of the literature." Journal of Education, Health and Sport 13, no. 2 (2022): 165–71. http://dx.doi.org/10.12775/jehs.2023.13.02.023.

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Background: Chloroquine is a 4-aminoquinoline derivative. Initially the substance was used as an antimalarial drug, but now chloroquine is also used to treat connective tissue diseases. It is a widely used drug in rheumatological diseases, especially in rheumatoid arthritis and systemic lupus erythematosus. A number of side effects have been reported in the public literature among patients using this drug. This article reviews side effects during long-term treatment of patients with rheumatoid arthritis. Materials and methods: A review of the literature available in the PubMed database was per

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ZDUN, Sylwia, Klaudia WALCZAK, Weronika GAWEŁ, et al. "Side effects of long-term treatment with chloroquine for rheumatoid arthritis - a review of the literature." Journal of Education, Health and Sport 13, no. 2 (2022): 165–71. https://doi.org/10.12775/JEHS.2023.13.02.023.

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<strong>ZDUN, Sylwia, WALCZAK, Klaudia, GAWEŁ, Weronika, WESOŁOWSKA, Zuzanna, JĘDRUSZCZAK, Przemysław, GRZYWNA, Natalia, NEMECZEK, Sylwia, MERKISZ, Konrad, GRZYBOWSKI, Jakub & WALCZAK, Patrycja. Side effects of long-term treatment with chloroquine for rheumatoid arthritis - a review of the literature</strong><strong>. Journal of Education, Health and Sport. 2023;13(2):1</strong><strong>65</strong><strong>-1</strong><strong>71</strong><strong>. eISSN 2391-8306. DOI </strong><strong>https://dx.doi.org/10.12775/JEHS.2023.13.02.02</strong><strong>3</strong> <strong>https://apcz.umk.pl/JEHS/art

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Blackard, W. G., R. M. Smith, and L. Jarett. "Insulin processing by cultured hepatocytes." American Journal of Physiology-Endocrinology and Metabolism 250, no. 2 (1986): E148—E155. http://dx.doi.org/10.1152/ajpendo.1986.250.2.e148.

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The chloroquine-sensitive and chloroquine-insensitive steps in insulin degradation by cultured hepatocytes have been explored by employing low temperature to retard processing. Under standard conditions (90 min association and 60 min dissociation) chloroquine inhibited insulin degradation at 15 degrees C but not at 37 degrees C. However, if the association and dissociation periods were short so that only early degradation was examined, marked inhibition of insulin degradation by chloroquine could also be observed at 37 degrees C. This inhibitory effect was observed only during the first 15 min

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Ridley, R. G., W. Hofheinz, H. Matile, et al. "4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum." Antimicrobial Agents and Chemotherapy 40, no. 8 (1996): 1846–54. http://dx.doi.org/10.1128/aac.40.8.1846.

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We have synthesized several 4-aminoquinolines with shortened side chains that retain activity against chloroquine-resistant isolates of Plasmodium falciparum malaria (W. Hofheinz, C. Jaquet, and S. Jolidon, European patent 94116281.0, June 1995). We report here an assessment of the activities of four selected compounds containing ethyl, propyl, and isopropyl side chains. Reasonable in vitro activity (50% inhibitory concentration, < 100 nM) against chloroquine-resistant P. falciparum strains was consistently observed, and the compounds performed well in a variety of plasmodium berghei animal

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FRANCO, YESENIA L., CHRISTINE KHAN, and SIHEM AIT-OUDHIA. "Pharmacodynamic Modeling Identifies Synergistic Interaction Between Chloroquine and Trastuzumab in Refractory HER2- positive Breast Cancer Cells." Cancer Diagnosis & Prognosis 3, no. 2 (2023): 175–82. http://dx.doi.org/10.21873/cdp.10198.

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Background/Aim: Despite improvements in HER2-positive breast cancer (BC) patients’ outcomes with trastuzumab, the occurrence of intrinsic or acquired resistance presents a clinical challenge. Here, we quantitatively assess the combinatorial effects of chloroquine, an autophagy inhibitor, with trastuzumab on JIMT-1 cells, a HER2-positive BC cell-line primarily resistant to trastuzumab. Materials and Methods: The temporal changes in JIMT-1 cellular viability were assessed using the CCK-8 kit, where JIMT-1 cells were exposed for 72-h to trastuzumab (0.007-17.19 μM) or chloroquine (5-50 μM) as sin

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&NA;. "Chloroquine see Proguanil/chloroquine." Reactions Weekly &NA;, no. 287 (1990): 6. http://dx.doi.org/10.2165/00128415-199002870-00013.

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Zhou, Qi, Xinzhou Yang, Mingrui Xiong, et al. "Chloroquine Increases Glucose Uptake via Enhancing GLUT4 Translocation and Fusion with the Plasma Membrane in L6 Cells." Cellular Physiology and Biochemistry 38, no. 5 (2016): 2030–40. http://dx.doi.org/10.1159/000445562.

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Background/Aims: Chloroquine can induce an increase in the cellular uptake of glucose; however, the underlying mechanism is unclear. Methods: In this study, translocation of GLUT4 and intracellular Ca2+ changes were simultaneously observed by confocal microscope in L6 cells stably over-expressing IRAP-mOrange. The GLUT4 fusion with the plasma membrane (PM) was traced using HA-GLUT4-GFP. Glucose uptake was measured using a cell-based glucose uptake assay. GLUT4 protein was detected by Western blotting and mRNA level was detected by RT-PCR. Results: We found that chloroquine induced significant

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1391 (2012): 16. http://dx.doi.org/10.2165/00128415-201213910-00057.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 696 (1998): 6. http://dx.doi.org/10.2165/00128415-199806960-00015.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 711 (1998): 7. http://dx.doi.org/10.2165/00128415-199807110-00020.

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Dissertations / Theses on the topic "Chloroquine"

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Mahon, Gerald J. "Studies on chloroquine retinopathy." Thesis, Queen's University Belfast, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388235.

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LAGARDE, CLAIRE. "Intoxication aigue par la chloroquine." Lille 2, 1997. http://www.theses.fr/1997LIL2P052.

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Eliot, Marc. "La chloroquine : aspect toxicologique actuel." Lyon 1, 1990. http://www.theses.fr/1990LYO1M243.

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Caliez, Catherine. "Contribution au dosage immunochimique de la chloroquine dans les milieux biologiques." Paris 5, 1988. http://www.theses.fr/1988PA05P608.

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Kendrick, Kelsie Lynn. "Mimicking Metabolism of a Reversed Chloroquine Antimalarial." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/2085.

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The aim of this study was to elucidate the oxidation products of a candidate antimalarial drug, PL69, using a porphyrin system and to determine the accuracy of the oxidation products produced, as compared to what is expected in metabolism. PL69 is a reversed chloroquine (RCQ) that is active against chloroquine resistant malaria. Porphyrin oxidation systems have been shown to mimic in vitro enzymatic metabolism reactions. PL69 and its known metabolite, PL16, were incubated with the porphyrin system, and then the oxidation products were collected and separated by HPLC. The oxidation products wer

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Onde, Olivier. "Actualités en réanimation pré-hospitalière et hospitalière immédiate des intoxications aigues par la chloroquine." Montpellier 1, 1989. http://www.theses.fr/1989MON11325.

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Jehl, Patrick. "Mécanismes de la chloroquinorésistance chez "Plasmodium falciparum" : intérêt de l'étude de la multirésistance des cellules cancéreuses." Paris 5, 1989. http://www.theses.fr/1989PA05P070.

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Ng, Anna. "Taste-masked and controlled-release formulations of chloroquine." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267929.

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Saliba, Kevin John. "Chloroquine accumulation in Plasmodium falciparum isolated digestive vacuoles." Doctoral thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/26631.

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Due to the development of drug-resistance by Plasmodium falciparum, the utilisation of chloroquine, a cheap and effective antimalarial has become limited. The mechanism of chloroquine-resistance is, at best, unresolved. This thesis describes an investigation of chloroquine accumulation in pure and intact Plasmodium falciparum isolated digestive vacuoles, the site of chloroquine accumulation and action. Marker enzymes and gel electrophoresis were used to demonstrate purity, and electron microscopy to verify integrity of isolated vacuoles. Using this method, vacuoles were isolated in a yield hig

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Murphy, Kevin Vincent. "Design and Synthesis of Novel Chloroquine-based Antimalarials." PDXScholar, 2015. https://pdxscholar.library.pdx.edu/open_access_etds/2623.

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Malaria is an infectious, often fatal disease that afflicts nearly 200 million people every year. The disease, characterized by recurring and extreme flu-like symptoms, is caused by the protozoan parasite Plasmodium falciparum. Victims usually contract the disease through a mosquito vector. Chloroquine is a chemotherapeutic that was introduced in the 1940s. For many years the drug was the foremost treatment of malaria, being effective and producing few side effects. Unfortunately, tolerance to chloroquine developed when the parasite evolved a resistance mechanism. Newer drugs have been develop

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Books on the topic "Chloroquine"

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Browning, David J. Hydroxychloroquine and Chloroquine Retinopathy. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0597-3.

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Takanori, Gotō. Japan's dark side to progress: The struggle for justice for pharmaceutical victims of Japan's post war economic boom. Manbousha, 1991.

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Takanori, Gotō. Japan's dark side to progress: The struggle for justice for pharmaceutical victims of Japan's post war economic boom. Manbousha, 1991.

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Lee, Andrew Hojin. Investigating mutability and the plasmodium falciparum chloroquine resistance transporter in drug resistant malaria parasites. [publisher not identified], 2016.

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Sharan, Sumit. Effects of chloroquine on MCF7-ADR and MCF7-WT human breast cancer cell lines. Laurentian University, 1998.

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Gotō, Takanori. Japan's dark side to progress: The struggle for justice for pharmaceutical victims of Japan's post war economic boom. Manbousha, 1991.

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Kim, Jonathan Young. Structural Investigation of Plasmodium falciparum Chloroquine Resistance Transporter in the Context of Anti-Malarial Drug Resistance. [publisher not identified], 2019.

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Mazonde, Isaac Ncube. Malaria epidemiological case study: An assessment of the attitudes of the risk population towards curative chloroquin tablets in Ngamiland, North West Botswana. National Institute of Development Research and Documentation, University of Botswana, 1988.

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9

Singh, Sonia. Effects of chloroquine on growth and energy metabolism of MCF7-ADR and MCF7-WT human breast cancer cell lines. Laurentian University, 1999.

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Browning, David J. Hydroxychloroquine and Chloroquine Retinopathy. Springer London, Limited, 2014.

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Book chapters on the topic "Chloroquine"

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Gooch, Jan W. "Chloroquine." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_13385.

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de Groot, Anton C. "Chloroquine." In Monographs In Contact Allergy. CRC Press, 2022. http://dx.doi.org/10.1201/9781003158004-126.

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Jones, Alison L. "Chloroquine and Quinine." In Critical Care Toxicology. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20790-2_99-1.

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Medina, Carlos A. "Chloroquine/Hydroxychloroquine Toxicity." In Manual of Retinal Diseases. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-20460-4_85.

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Jones, Alison L. "Chloroquine and Quinine." In Critical Care Toxicology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-17900-1_99.

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Browning, David J. "Preclinical Foundations: Relevant Anatomy and Physiology." In Hydroxychloroquine and Chloroquine Retinopathy. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0597-3_1.

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Browning, David J. "Clinical Examples in Managing Patients Taking 4-Aminoquinolines." In Hydroxychloroquine and Chloroquine Retinopathy. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0597-3_10.

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Browning, David J. "Pharmacology of Chloroquine and Hydroxychloroquine." In Hydroxychloroquine and Chloroquine Retinopathy. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0597-3_2.

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Browning, David J. "Toxicology of Hydroxychloroquine and Chloroquine and the Pathology of the Retinopathy They Cause." In Hydroxychloroquine and Chloroquine Retinopathy. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0597-3_3.

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Browning, David J. "Definitions of Hydroxychloroquine and Chloroquine Retinopathy." In Hydroxychloroquine and Chloroquine Retinopathy. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0597-3_4.

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Conference papers on the topic "Chloroquine"

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Obanina, Natalia, and Nataliya Bgatova. "Effect of Lithium and Chloroquine on Neuronal Ultrastructure in a Melanoma Mice Model." In 2024 IEEE International Multi-Conference on Engineering, Computer and Information Sciences (SIBIRCON). IEEE, 2024. http://dx.doi.org/10.1109/sibircon63777.2024.10758443.

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Oreofe, Toyin A., Adejumoke A. Inyinbor, Olugbenga S. Bello, and Oladipupo O. Ogunleye. "Adsorption Isotherm, Kinetics and Thermodynamics studies on Chloroquine sequestration using coconut shell activated carbon." In 2024 International Conference on Science, Engineering and Business for Driving Sustainable Development Goals (SEB4SDG). IEEE, 2024. http://dx.doi.org/10.1109/seb4sdg60871.2024.10629925.

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Sari, Dewi Indra, and Mardiati Nadjib. "The Role of Chloroquine and Hydroxychloroquine in Prophylaxis of Covid-19: A Literature Review." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.05.33.

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ABSTRACT Background: A pandemic potential Covid-19 spread rapidly worldwide. Ministry of Health, Republic Indonesia recommended one of the Covid-19 treatments with combination of hydroxychloroquine/ chloroquine and azithromycin. However, the effectiveness and safety of antimalaria regime remain debating topic. This study aimed to investigate the role of chloroquine and hydroxychloroquine in prophylaxis of Covid-19. Subjects and Method: A systematic review was conducted by searching from PubMed, SpringerLink, and Cochrane Library databases. The keywords were “prophylaxis”, “chloroquine” OR “hyd

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Pihlajoki, Marjut, Katja Eloranta, Antti Kyrönlahti, and Markku Heikinheimo. "Abstract 5408: Chloroquine inhibits PARP expression in hepatoblastoma." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-5408.

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Amaravadi, Ravi K. "Abstract SY01-04: Chloroquine derivatives as anticancer agents." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-sy01-04.

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Pedrosa, Leandro F., Antônia C. R. Furtado, Carolina T. Machado, et al. "Design and Synthesis of New Phosphoramidates Chloroquine Analogs." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0213-2.

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Cyert, Lynn. "Testing for Acquired Color Vision Deficiencies in Patients Receiving Hydroxychloroquine (Plaquenil) Therapy." In Advances in Color Vision. Optica Publishing Group, 1992. http://dx.doi.org/10.1364/acv.1992.fb17.

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Hydroxychloroquine sulfate--trade name Plaquenil--is an antimalarial therapeutic agent derived from chloroquine. Hydroxychloroquine is also important for its use as an anti-inflammatory agent in the treatment of rheumatoid arthritis and discoid and systemic lupus erythematosus(1).

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Casado, E., M. Larrosa, J. Gratacos, J. Font, JM Martinez, and C. Tolosa. "OP0131 Chloroquine myopathy: prevalence and clinical features (preliminary data)." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.581.

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Gonzalez-Dominguez, J., M. Santos, A. Escudero, et al. "THU0203 Incidence of chloroquine retinopahy in rheumatoid arthritis patients." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.1105.

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S., Anil Kumar, Amrita Thakur, and Sreeharsha Nagaraja. "Computational studies on chloroquine derivatives as anti-malarial drugs." In 1ST INTERNATIONAL CONFERENCE ON ADVANCES IN NOVEL MATERIALS: Towards Sustainable Future (ICAN-24). AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0227883.

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Reports on the topic "Chloroquine"

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Kendrick, Kelsie. Mimicking Metabolism of a Reversed Chloroquine Antimalarial. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.2083.

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Murphy, Kevin. Design and Synthesis of Novel Chloroquine-based Antimalarials. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.2619.

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Tesfaselassie, Elias. Antimalarial Drug Discovery using Triazoles to Overcome Chloroquine Resistance. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.2503.

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Kyle, Dennis E., Wilbur K. Milhous, and Richard N. Rossan. Reversal of Plasmodium Falsiparum Resistance to Chloroquine in Panamanian Aotus Monkeys. Defense Technical Information Center, 1993. http://dx.doi.org/10.21236/ada263042.

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ลิขิตวิทยาวุฒิ, กิตติศักดิ์, та จิระพันธ์ กรึงไกร. สารต้านมาลาเรียจากน้ำเต้าลม : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 1996. https://doi.org/10.58837/chula.res.1996.13.

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ได้ทำการสกัดเอาสารบริสุทธิ์จากต้นน้ำเต้าลม Nepenthes thorelii Lec. (Nepenthaceae) แยกได้ 5 ชนิด ได้แก่ plumbagin, isoshinanolone, octadecly caffeate, 2-methylnaphthazarin และ droserone เมื่อนำสารเหล่านี้ไปทดสอบฤทธิ์ต้านมาลาเรียในจานทดลองโดยวิธีวัดปริมาณ [superscript 3H]hypoxanthine ที่เชื้อ Plasmodium falciparum สายพันธุ์ T[subscript 9/94] รับเข้าไป แล้วทำการเปรียบเทียบสารเหล่านี้กับยาต้านมาลาเรียที่ใช้กันในปัจจุบันได้แก่ pyrimethamine (IC[subscript 50] 11.29 ไมโครโมลาร์) และ chloroquine (IC[subscript 50] 0.09 ไมโครโมลาร์) พบว่า สารที่มีฤทธิ์ต้านมาลาเรียแรงได้แก่ plumbagin (IC[subscript 50] 0.

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Xia, Yuan, Ai Peng, Mingying Li, et al. Chloroquine and hydroxychloroquine for treatment of COVID-19: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.7.0110.

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Dacso, Clifford C., S. Hilsenbeck, M. Bondy L., et al. A Translational Approach to Validate in Vivo Anti-tumor Effects of Chloroquine on Breast Cancer Risk. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada586025.

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Chang, Raymond. A systematic review of randomized clinical trials assessing the prophylactic efficacy or chloroquine or hydroxychloroquine against COVID-19. INPLASY - International Platform of Registered Systematic Review Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.4.0101.

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Zhao, Yuwei, Wu Sun, Runzhi Qi, et al. Chloroquine combined with azithromycin in the treatment of novel coronavirus (COVID-19) pneumonia: study protocol for a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.1.0044.

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San Pedro, Ekaterina Ellyce. A brief historical overview of the antimalarials chloroquine and artemisinin: An investigation into their mechanisms of action and discussion on the predicament of antimalarial drug resistance. Iowa State University, 2021. http://dx.doi.org/10.31274/cc-20240624-10.

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