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Dissertations / Theses on the topic 'Clostridium perfringens'

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Published: 4 June 2021

Last updated: 25 July 2025

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1

Canard, Bruno. "Organisation genomique de clostridium perfringens." Paris 7, 1991. http://www.theses.fr/1991PA077145.

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Clostridium perfringens est un bacille a gram positif, pathogene pour l'homme et les animaux. Nous avons construit une carte physique et genetique du chromosome de la souche de reference cpn50, de type a, ainsi que de sept autres isolats appartenant aux serotypes a, b, d et e. Nous avons ainsi pu etudier comparativement l'organisation genomique des genes et loci impliques dans la maintenance des fonctions vitales de la bacterie, dans la virulence, et dans la plasticite genomique. Nous avons caracterise respectivement au niveau moleculaire les operons ribosomiques rrn, le gene nagh codant pour

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2

Stiles, Bradley G. "Purification and characterization of Clostridium perfringens iota toxin." Diss., Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/76516.

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Clostridium perfringens type E iota toxin is implicated in some cases of fatal diarrhea in calves, lambs, and guinea pigs. A crossreacting "iota-like" toxin, produced by Clostridium spiroforme, is responsible for antibiotic-associated and weaning related enterotoxemias of rabbits. Antisera developed against culture supernatant of either organism neutralized the biological activity of iota or iota-like toxin. By using C. spiroforme antiserum and crossed immunoelectrophoresis (crossed IEP), we found two cross-reacting antigens in C. perfringens type E supernatants. C. perfringens types A, B, C,

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3

Pérez, Janampa David Remy. "Caracterización toxigénica de la fosfolipasa C del Clostridium perfringens (Cp-PLC) y su relación con aislados de C. perfrigens de casos de enterotoxemia en alpacas." Master's thesis, Universidad Nacional Mayor de San Marcos, 2010. https://hdl.handle.net/20.500.12672/3262.

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La enterotoxemia, causada por el Clostridium perfringens, es la enfermedad infecciosa más importante que afecta a las alpacas, debido a que ocasiona elevadas tasas de mortalidad neonatal de hasta 70%. Recientes estudios han sugerido la participación de la Cp-PLC (C. perfringens fosfolipasa C) como factor de virulencia responsable del cuadro enterotoxemico en alpacas y otras especies domesticas. El presente estudio evaluó las características toxigénicas de la Cp-PLC y de sobrenadantes de diferentes aislados de C. perfringens obtenidos de casos de enterotoxemia en alpacas relacionándolos con sus

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4

Perelle, Sylvie. "Toxine IOTA de "Clostridium perfringens" et toxines apparentées." Paris 11, 1996. http://www.theses.fr/1996PA114811.

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5

Xie, Xinye. "Purification and characterization of a blood group A₂degrading [alpha]-N-acetylgalactosaminidase from clostridium perfringens." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3012978.

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6

Eaton, Julian Timothy. "Structural studies of Clostridium perfringens alpha toxin." Thesis, Birkbeck (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417896.

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7

Griffiths, Nicola Jane. "Studies on Clostridium perfringens in the horse." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367091.

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8

Hunter, Sophie Emma Clare. "Molecular genetics of Clostridium perfringens epsilon-toxin." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316420.

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9

Justin, Neil. "Structural studies of clostridium perfringens alpha toxin." Thesis, Birkbeck (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392355.

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10

Russell, Katherine Margaret. "Intestinal responses to Clostridium perfringens in broilers." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25514.

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Clostridium perfringens is the aetiological agent of Necrotic enteritis (NE); a disease that impacts on the health and welfare of broilers. This disease is a large cost to the industry and presents as lesions in the small intestine hindering productivity. Antibiotics are commonly used to treat NE but as pressure increases to limit their use further information about disease onset and broiler responses to the bacteria and it’s virulence factors during infection is required to implement new preventative measures and treatments. NetB is a secreted toxin from C. perfringens which has an important

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11

Zimmer, Markus. "Complete genome sequence and characterization of the lysis system of the temperate Clostridium perfringens bacteriophage f3626 [phi3626]." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965243400.

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12

Flores, Díaz Marietta. "A UDP-glucose deficient mutant cell line as a model to study the cytotoxicity of Clostridium perfringens PLC /." Stockholm : Karolinska Univ. Press, 2001. http://diss.kib.ki.se/2001/91-7349-087-3/.

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13

Cole, Ambrose Ralph. "Structural studies of the toxins of Clostridium perfringens." Thesis, Birkbeck (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408277.

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14

Miyashiro, Simone. "Caracterização de isolados de Clostridium perfringens de ruminantes." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-16092014-155341/.

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C. perfringens é uma bactéria anaeróbia presente no intestino delgado do homem e animais em equilíbrio e, sob a ação de alguns fatores predisponentes como mudança brusca de alimentação ou super alimentação, stress no manejo ou alto parasitismo intestinal, há a proliferação do microrganismo com a consequente produção de potentes toxinas que provocam a morte do animal. Dentre as toxinas principais destaca-se a toxina alfa, importante fator de virulência, produzida por todos os tipos de C. perfringens, sendo os pertencentes ao tipo A os maiores produtores. A fim de caracterizar o microrganismo em

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15

O'Brien, David Kenneth. "The Interactions of Clostridium Perfringens With Phagocytic Cells." Diss., Virginia Tech, 2003. http://hdl.handle.net/10919/27164.

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Clostridium perfringens is the most common cause of gas gangrene (clostridial myonecrosis), a disease that begins when ischemic tissues become contaminated with C. perfringens. C. perfringens quickly multiplies in ischemic tissues and spreads to healthy areas, leading to high levels of morbidity and mortality. As a species, the bacterium can synthesize thirteen different toxins. The alpha toxin (PLC) and perfringolysin O (PFO) are thought to be important virulence factors in gangrene. We wished to understand how C. perfringens is capable of avoiding killing by the host immune system, and d

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16

Netherwood, Trudy. "The association of Clostridium perfringens with foal diarrhoea." Thesis, Open University, 1995. http://oro.open.ac.uk/57556/.

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Several case reports of Clostridium perjringens involvement in equine enteric disease have not identified the prevalence and statistical association of these bacteria with foal diarrhoea. Each of five methods which favoured the recovery of C. perjringens in different physiological states were chosen to improve the sensitivity of isolation in a survey of foal diarrhoea for C. perjringens and other pathogens. C. perjringens was significantly associated with foal diarrhoea (isolated from 57% of 421 scouring anjmals but from only 33% of 222 controls; odds ratio 7.4; p < 0.001 by multivariate analy

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17

Eberl, Steven G. "Clostridium Perfringens: An Adjunctive Indicator in Nonpoint Pollution." DigitalCommons@USU, 1986. https://digitalcommons.usu.edu/etd/4397.

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Clostridium perfringens (CP) was evaluated as an additional indicator in assessing impacts and sources of microbial pollution in the Idaho-Utah Cache Valley . Point , nonpoint, river water, and animal fecal samples were analyzed for CP, total coliforms, fecal collforms, and fecal streptococci. Monthly river samples consistently contained <20 CP/100 mL , but concentrations of the other indicators varied significantly by location and date. Two sample stations consistently had CP concentrations greater than 20 / 100 mL . One of these stations was influenced by an upstream wastewater discharge . C

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18

ALBERTIN, FILIPPI ANNE-MARIE. "Les toxi-infections alimentaires collectives a clostridium perfringens." Strasbourg 1, 1990. http://www.theses.fr/1990STR15021.

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19

Anderson, Michael Anthony. "Porcine Enteric Disease Caused by Clostridium difficile and Clostridium perfringens: Epidemiology, Pathogenesis and Immunity." Diss., The University of Arizona, 2008. http://hdl.handle.net/10150/195681.

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Clostridium difficile and Clostridium perfringens are among the most commonagents of enteric disease in both humans and domestic animals. The former continues to increase in prevalence and diseases caused by the latter persist. Infection with a recently emergedhypervirulent strain (NAP1/027/III) of C. difficile is increasingly common andserious sequelae and fatalities are much more common in these patients. In neonatalpiglets, C. difficile infection (CDI) has become a common occurrence. Historically,isolation of C. perfringens type A from patients with enteric disease has been consideredincons

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20

Iwanejko, Lesley Ann. "Cloning the enterotoxin gene from Clostridium perfringens type A." Thesis, University of Nottingham, 1991. http://eprints.nottingham.ac.uk/12195/.

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A C. perfringens type A genomic library was constructed in E. coli by banking overlapping 6-10 kbp Hind III fragments of chromosomal DNA from the enterotoxin (CPE) positive strain NCTC 8239 into the pUC derived vector pHG165. The library was screened by colony hybridization with a degenerate 26 bp oligonucleotide probe, derived from the amino acid sequence CPE9_17A. complex mixture of plasmid DNA was isolated from the only hybridization positive clone. A second round of screening picked out a single plasmid, with an apparently altered copy number, pLWl, that carried the CPE gene, cpe, on a 6.8

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21

Brown, Robert Christopher. "Development of a novel expression system in Clostridium perfringens." Thesis, Open University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321561.

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22

Orsburn, Benjamin. "Factors Affecting the Heat Resistance of Clostridium perfringens Spores." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/27697.

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The bacterium Clostridium perfringens is a gram-positive anaerobe responsible for many diseases in man and other animals, the most common of which is acute food poisoning (AFP). It is estimated that nearly 240,000 cases of AFP occur each year in the U.S. The C. perfringens spore plays an important role in this infection. The heat resistance of the spore allows the organism to survive the cooking process, grow in the cooling food, and infect the victim. Despite the occurrence of this disease and the importance of the spore to this process, little work has been performed to determine how heat re

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23

Abraham, Lawrence Joseph. "Molecular genetics of antibiotic resistance determinants from Clostridium perfringens." Thesis, Abraham, Lawrence Joseph (1986) Molecular genetics of antibiotic resistance determinants from Clostridium perfringens. PhD thesis, Murdoch University, 1986. https://researchrepository.murdoch.edu.au/id/eprint/53043/.

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Clostridium perfringens is a sporulating, Gram positive, anaerobic bacterium that is a normal inhabitant of the gastrointestinal tract and is known to cause a number of diseases in both man and animals. Conjugative tetracycline resistance plasmids from C. perfringens strains isolated in Australia, the United States, France, Belgium, and Japan were analysed by comparison with the reference plasmid, pCW3. This conjugative 47 kilobasepair (kb) plasmid was isolated from a human C. perfringens strain and confers inducible tetracycline resistance. Fifteen of the plasmids encoded tetracycline resista

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24

Meer, Ralph Raymond. "Rapid methods for the detection of toxigenic Clostridium perfringens." Diss., The University of Arizona, 1996. http://hdl.handle.net/10150/290593.

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Clostridium perfringens may be the most widely occurring bacterial pathogen and is responsible for a variety of diseases in both humans and animals. The virulence of this organism is associated with the ability to produce an estimated 17 potential exotoxins. The production of one or more of the five major toxins (α,β,ε, and ι) is the basis for placing isolates into five toxigenic types, A through E. Enterotoxin (CPE), is not used in typing but is considered a major virulence factor. A multiplex PCR genotyping assay was developed, utilizing primers derived from sequences of cpa, cpb, etx, iA, a

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25

Camiade, Émilie. "Étude de deux autolysines à activité N-acétylglucosaminidase chez Clostridium perfringens et Clostridium difficile." Rouen, 2010. http://www.theses.fr/2010ROUES025.

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L'objectif de ce travail était de caractériser et d'étudier le rôle de deux peptidoglycane hydrolases à activité N-acétylglucosaminidase chez Clostridium perfringens et Clostridium difficile. Les peptidoglycane hydrolases possèdent en effet un rôle essentiel dans la croissance bactérienne, peuvent contribuer à la virulence de certaines espèces pathogènes, et peuvent être impliquées dans l'activité bactéricide des antibiotiques inhibiteurs de la synthèse de la paroi. Le lien phylogénétique des genres Staphylococcus et Clostridium nous a permis de caractériser, par analyse génomique, deux gènes

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26

Beraldo, Massoli Mariana Casteleti [UNESP]. "Prevalência de Clostridios sulfito redutores e Clostridium perfringens na mucosa intestinal de frangos de corte." Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/115976.

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Made available in DSpace on 2015-03-03T11:52:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-06-27Bitstream added on 2015-03-03T12:07:01Z : No. of bitstreams: 1 000811220.pdf: 462686 bytes, checksum: 819f94ea9094e6242a1747ff899e45b2 (MD5)<br>O gênero Clostridium é amplamente distribuído na natureza, está presente no solo e conteúdo intestinal dos animais, produzem toxinas que são capazes de provocar doenças e intoxicações. O Clostridium perfringens está envolvido com prejuízos na avicultura, pois a doença (Enterite Necrotica) na maioria das vezes é subclínica, e o produtor só obser

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27

Beraldo, Massoli Mariana Casteleti. "Prevalência de Clostridios sulfito redutores e Clostridium perfringens na mucosa intestinal de frangos de corte /." Jaboticabal, 2014. http://hdl.handle.net/11449/115976.

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Orientador: Ruben Pablo Schocken-Iturrino<br>Banca: Clovis Wesley Oliveira de Souza<br>Banca: Caroline Petters Pigato de Nardi<br>Banca: Luiz Augusto do Amaral<br>Banca: Antonio Carlos Paulillo<br>Resumo: O gênero Clostridium é amplamente distribuído na natureza, está presente no solo e conteúdo intestinal dos animais, produzem toxinas que são capazes de provocar doenças e intoxicações. O Clostridium perfringens está envolvido com prejuízos na avicultura, pois a doença (Enterite Necrotica) na maioria das vezes é subclínica, e o produtor só observa na hora do abate que a ave não ganhou o peso e

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28

Lippke, Ricardo Tesche. "Estudo caso controle avaliando a freqüencia dos principais agentes causadores de diarréia neonatal em suínos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/12706.

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A diarréia é o principal evento clínico observado no período neonatal em leitões (como conseqüência das doenças entéricas). Além de contribuir para piora no ganho de peso diário e conversão alimentar do animal causa aumento na mortalidade e gastos com medicamentos. O presente trabalho teve como objetivo determinar a freqüência dos principais agentes virais (rotavírus), bacterianos (E. coli, Clostridium perfringens tipo A e C e Clostridium difficile) e parasitários (coccídeos e Cryptosporidium spp.) envolvidos na diarréia neonatal em leitegadas caso (com diarréia) e controle (sem diarréia). For

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29

Sawires, Youhanna Sobhy. "GENETIC ANALYSIS OF CLOSTRIDIUM PERFRINGENS: INSIGHT INTO EVOLUTION OF VIRULENCE." Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1231%5F1%5Fm.pdf&type=application/pdf.

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30

Johansson, Anders. "Clostridium perfringens the causal agent of necrotic enteritis in poultry /." Uppsala : Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200634.pdf.

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31

Correa, Alberto Enrique Estrada. "Studies of Clostridium perfringens Type A enteritis in the pig." Thesis, University of Glasgow, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328223.

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32

Leslie, Dario Lyall. "Genetic analysis of alpha toxin (phospholipase C) from Clostridium perfringens." Thesis, University of Newcastle Upon Tyne, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.346420.

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33

Bullifent, Helen Lisa. "The regulation of the alpha-toxin gene of Clostridium perfringens." Thesis, University of Sheffield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296729.

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34

Nikraftar, Sarah. "Localization of Type IV Pilin Polymerization Proteins in Clostridium perfringens." Thesis, Virginia Tech, 2015. http://hdl.handle.net/10919/71742.

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Clostridium perfringens is a spore-forming anaerobic Gram-positive rod which has gliding motility through type IV Pili (TFP). Since the discovery of TFP in Gram-positive bacteria is relatively new, more studies are required to understand the mechanism and interaction of the proteins of this machinery. Moreover, the similarities between TFP and type 2 secretion system (T2SS) suggest that C. perfringens has also a T2SS. We studied the localization of TFP ATPases, PilB1, PilB2 and PilT in Bacillus subtilis to compare the localization in an organism other than C. perfringens and which lacks any

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35

Harry, Kathryn Helene. "Sporulation and enterotoxin regulation by sigma factors in Clostridium perfringens." Thesis, Virginia Tech, 2008. http://hdl.handle.net/10919/42517.

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Clostridium perfringens is a leading cause of food poisoning annually in the United States. Ingested C. perfringens vegetative cells respond to the acidic conditions of the stomach by initiating sporulation. The process of sporulation is essential in the formation of an enterotoxin (CPE) that is responsible for the symptoms of acute food poisoning. During sporulation, the cell must differentiate into the mother cell and the forespore. Studies in Bacillus subtilis have shown that gene expression during sporulation is compartmentalized, with different genes expressed in the mother cell and t

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36

Hendrick, William Anthony. "Molecular Analysis of Type IV Pilus Assembly in Clostridium perfringens." Diss., Virginia Tech, 2016. http://hdl.handle.net/10919/81696.

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Clostridium perfringens is a Gram-positive anaerobe capable of causing disease in humans and many animals. C. perfringens is able to move across surfaces in a manner that is dependent on growth and type IV pili. Type IV pili are filaments that can be extended away from the cell by rapid polymerization, and retracted by depolymerization. Furthering the understanding of the initial and final energetic states of the pilins will reveal insights into possible mechanisms of type IV pilus assembly. Toward that end, a pilin was purified from the Gram-negative pathogen Pseudomonas aeruginosa and inco

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37

Botlhoko, Tuelo David. "Performance of Clostridium perfringens-challenged broilers inoculated with effective microorganisms." Pretoria : [s.n.], 2010. http://upetd.up.ac.za/thesis/available/etd-02192010-172630.

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38

Azevedo, Edisio Oliveira de. "Avaliação de vacinas contra Clostridium perfringens tipos C e D." Universidade Federal de Minas Gerais, 1997. http://hdl.handle.net/1843/BUOS-8PQKNM.

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Seven commercial vaccines against clostridiosis. which had in their composition type C and/or D Closmdzum pemingens toxoids. have been evaluated for sterility, residual toxicity and potency. Six vaccines were produced in Brazil and one was imported, a bivalent toxoid standard of C. perjiingens type C and D has been used as a test control. All tested vaccines were sterile when cultivated in bacteria and fungi growth media. and were innocuous when administrated to mice via intraperitoneal route. ln relation to the potency, evaluated by mice semm neutralization tests using immunized rabbits sera

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39

Alnassan, Alaa Aldin. "Kokzidien und Clostridium perfringens: Studien an Koinfektionsmodellen zur Induktion und Bekämpfung der Nekrotischen Enteritis beim Huhn." Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-190110.

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Die nekrotische Enteritis (NE) und Kokzidiose des Huhnes sind häufige Darmerkrankungen weltweit und führen jedes Jahr zu hohen Wirtschaftsverlusten als Folge der Mortalität und Kosten für Behandlung und Bekämpfung. Die beiden Erkrankungen werden meistens bei Mastbroilern zwischen der 3. und 6. Lebenswoche festgestellt. Weil die leistungsfördernden Antibiotika im Geflügelfutter in der EU nicht mehr eingesetzt werden dürfen, ist das Risiko der NE in den letzten Jahren gestiegen. Fischmehl, Stress und Krankheiten sind prädisponierende Faktoren für die Entstehung der NE aber auch die Hühnerkokzidi

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40

Petit, Laetitia. "Toxine epsilon de clostridium perfringens : mode d'action dans le modele cellulaire mdck et analyse de sa production chez c. perfringens (doctorat : micrbiologie)." Paris 11, 1998. http://www.theses.fr/1998PA114842.

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41

Farrow, Kylie Ann 1973. "Analysis of clostridial MLS resistance determinants." Monash University, Dept. of Microbiology, 2001. http://arrow.monash.edu.au/hdl/1959.1/8319.

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42

Marvaud, Jean-Christophe. "Contribution a l'etude des proteines associees aux neurotoxines clostridiennes et vectorisation de proteines dans les cellules (doctorat : microbiologie)." Paris 11, 1998. http://www.theses.fr/1998PA114851.

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43

Ali, Ali Abdulkareem Ali. "Isolation and characterization of Clostridium perfringens bacteriophages and optimization of electro-transformation parameters for Clostridium difficile." Thesis, University of Leicester, 2018. http://hdl.handle.net/2381/42289.

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Clostridium perfringens (C. perfringens) is responsible for a variety of diseases in humans and animals. Clostridium difficile (C. difficile) is the leading cause of antibiotic-associated diarrhoea. The available treatments for infections caused by both pathogens are not effective. Bacteriophage (phage) therapy is a promising treatment strategy to tackle and treat any infections or diseases caused by C. perfringens or C. difficile. The aim of this study was to isolate bacteriophages that infect C. perfringens and characterize them, and to optimize electroporation parameters for C. difficile wi

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44

Pérez, Janampa David Remy. "Genotipificación y subtipificación de Clostridium perfringens aislados de crías de alpacas muertas por enterotoxemia." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2006. https://hdl.handle.net/20.500.12672/665.

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La enterotoxemia, causada por el Clostridium perfringens, es la enfermedad infecciosa más importante que afecta a las alpacas, debido a que ocasiona elevadas tasas de mortalidad neonatal de hasta 70%. A pesar de esto, existe poca información sobre los factores de virulencia (toxinas) del C. perfringens que participan en la etiopatogénesis de la enfermedad. El presente estudio tuvo como objetivo determinar el genotipo de los C. perfringens aislados de casos de enterotoxemia en base a la presencia de los genes (cpa, cpb, etx e iap) codificantes de las toxinas principales (α, β, ε y ι) así como e

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45

Jepson, Marie Alice. "The role of the C-Domain of clostridium perfringens Î±-toxin." Thesis, Birkbeck (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247080.

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46

McGinley, Susan. "Clostridium perfringens: New Ways to Type Strains of a Deadly Bacteria." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 1999. http://hdl.handle.net/10150/622290.

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47

GUILLOUARD, ISABELLE. "Organisation structurale et fonctionnelle de la toxine alpha de clostridium perfringens." Paris 7, 1997. http://www.theses.fr/1997PA077115.

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La toxine-alpha de clostridium perfringens, principal facteur de virulence produit par les souches pathogenes, joue un role preponderant dans le developpement de la gangrene gazeuse. Phospholipase c, elle peut hydrolyser la phosphatidylcholine (lecithine) et la sphingomyeline, acides gras majeurs des membranes des cellules eucaryotes. Elle est aussi letale, necrosante et hemolytique. Bien caracterisee biochimiquement, les relations existant entre la structure et le mode d'action de la toxine alpha sont encore imprecises. Grace a la remarquable similitude existant entre les 2/3 n-terminaux de l

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Horton, William Henry Clay. "Characterization of the Components of Carbon Catabolite Repression in Clostridium perfringens." Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/36119.

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Clostridium perfringens is a versatile pathogen capable of causing a wide array of diseases, ranging from clostridial food poisoning to tissue infections such as gas gangrene. An important factor in virulence as well as in the distribution of C. perfringens is its ability to form an endospore. The symptoms of C. perfringens food poisoning are directly correlated to the release of an enterotoxin at the end of the sporulation process. The sporulation process in C. perfringens is subject to carbon catabolite repression (CCR) by sugars, especially glucose. CCR is a regulatory pathway that alters t

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49

Gomes, Alexis de Matos. "Isolamento e tipifícação genotípica de Clostridium Perfringens em frangos de corte." Universidade Federal de Minas Gerais, 2007. http://hdl.handle.net/1843/VETC-7AXLVJ.

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Clostridium perfringens is an anaerobic Gram-positive bacterium which causes gaseous gangrene and enterotoxaemias in humans and domestic animals besides being the primary cause of necrotic enteritis in poultry. Clostridium perfringens strains were isolated 171/250 (68.4%) from the intestinal content of broiler chickens sampled in a slaughterhouse in Pará de Minas, MG. Clostridium perfringens were identified according to Gram staining, lecithinase test on agar TSC-egg yolk, haemolysis in desfibrinated horse blood agar and biochemical tests. Clostridium perfringens strains were classified into f

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50

Fohler, Svenja [Verfasser]. "Occurrence of Clostridium botulinum neurotoxin genes and toxin-genotypes of Clostridium perfringens in dairy cattle / Svenja Fohler." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2016. http://d-nb.info/1104403897/34.

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