Relevant bibliographies by topics / Cluster mutation

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Cluster mutation'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Cluster mutation"

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Conroy, Jeffrey M., Sarabjot Pabla, Marc S. Ernstoff, et al. "Comprehensive immune and mutational profile of melanoma." Journal of Clinical Oncology 36, no. 5_suppl (2018): 182. http://dx.doi.org/10.1200/jco.2018.36.5_suppl.182.

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182 Background: The association between tumor mutational profiles and immune signatures has not been well-characterized. Methods: 306 melanoma samples were tested by NGS using a comprehensive cancer panel for mutational status and an immune response panel which interrogates the expression profile of 54 validated immune-related genes. The ranking of gene expression, mutational burden and 7 immune phenotypes was compared to a reference population. 38% cases were positive for activating BRAF mutations, 12% for RAS, and 6% for NF1. The remaining 44% were considered triple wild type. Principal comp
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Montalban-Bravo, Guillermo, David Swanson, Rashmi Kanagal-Shamanna, et al. "Influence of Co-Mutational Patterns in Disease Phenotype and Clinical Outcomes of Chronic Myelomonocytic Leukemia." Blood 142, Supplement 1 (2023): 4601. http://dx.doi.org/10.1182/blood-2023-178061.

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Introduction: Chronic myelomonocytic leukemia (CMML) is characterized by recurrent somatic mutations in a conserved number of genes and functional pathways. Although specific genomic events are associated with disease phenotype and prognosis, identification of genomically-defined disease subgroups based on common recurrent cooperative genomic patterns is needed to refine disease classification and identify disease subsets with unique clinical behavior. Methods: To evaluate if CMML is defined by recurrent co-mutational profiles defining unique clinicopathologic subgroups we evaluated a cohort o
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Mandilaras, Victoria, Swati Garg, Michael Cabanero, et al. "TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses." International Journal of Gynecologic Cancer 29, no. 2 (2019): 346–52. http://dx.doi.org/10.1136/ijgc-2018-000087.

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ObjectiveMutations in TP53 are found in the majority of high grade serous ovarian cancers, leading to gain of function or loss of function of its protein product, p53, involved in oncogenesis. There have been conflicting reports as to the impact of the type of these on prognosis. We aim to further elucidate this relationship in our cohort of patients.Methods229 patients with high grade serous ovarian cancer underwent tumor profiling through an institutional molecular screening program with targeted next generation sequencing. TP53 mutations were classified using methods previously described in
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Yu, Zhenhua, and Fang Du. "AMC: accurate mutation clustering from single-cell DNA sequencing data." Bioinformatics 38, no. 6 (2021): 1732–34. http://dx.doi.org/10.1093/bioinformatics/btab857.

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Abstract Summary Single-cell DNA sequencing (scDNA-seq) now enables high-resolution profiles of intra-tumor heterogeneity. Existing methods for phylogenetic inference from scDNA-seq data perform acceptably well on small datasets but suffer from low computational efficiency and/or degraded accuracy on large datasets. Motivated by the fact that mutations sharing common states over single cells can be grouped together, we introduce a new software called AMC (accurate mutation clustering) to accurately cluster mutations, thus improve the efficiency of phylogenetic inference. AMC first employs prin
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Huang, He, Zhimin Wang, Hao Chen, et al. "Co-mutation-based subtyping of Chinese patients with gastric cancer." Journal of Clinical Oncology 41, no. 16_suppl (2023): e16070-e16070. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e16070.

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e16070 Background: The incidence of gastric cancer is decreasing globally, in contrast, that of Chinese patients has been increased from 35.9% to 48.3%. In-depth investigation of the characteristic of Chinese gastric cancer patients could help to understand the disease mechanism and improve the treatment of gastric cancer. Methods: Tumor tissues were obtained from 96 Chinese gastric cancer patients and tested by high-coverage ( > 1000x) panel sequencing containing 624 cancer-related genes. Genomic mutations including substitutions, insertions, deletions, rearrangements, fusions, and copy nu
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Papanicolau-Sengos, Antonios, Sarabjot Pabla, Grace K. Dy, et al. "Correlation of lung cancer mutational profile with immune profile." Journal of Clinical Oncology 36, no. 5_suppl (2018): 146. http://dx.doi.org/10.1200/jco.2018.36.5_suppl.146.

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146 Background: The association between neoplasm mutational and immune profiles has not been well-characterized. Methods: We collected 26 lung cancer formalin-fixed paraffin embedded (FFPE) samples which had been tested with a comprehensive mutation profile to detect clinically actionable mutations, and a comprehensive immune gene expression profile, which interrogates PD-L1 immunohistochemistry (IHC), PD-L1/2 copy number, CD3/CD8 IHC, microsatellite instability status, mutational burden, and the expression profile of 54 immune-related genes. The ranking of gene expression and 7 immune phenoty
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Lanino, Luca, Somedeb Ball, Jan Philipp Bewersdorf, et al. "Data-Driven Harmonization of 2022 Who and ICC Classifications of Myelodysplastic Syndromes/Neoplasms (MDS): A Study By the International Consortium for MDS (icMDS)." Blood 142, Supplement 1 (2023): 998. http://dx.doi.org/10.1182/blood-2023-186580.

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Background. The inclusion of gene mutations and chromosomal abnormalities in the 2022 WHO and ICC Classifications of MDS has enhanced diagnostic precision and is expected to improve clinical decision-making process. Although these two systems share similarities, clinically relevant discrepancies still exist and potentially cause inconsistency in their adoption in a clinical setting. In this study on behalf of the International Consortium for MDS (icMDS), we adopted a data-driven approach to provide a harmonization roadmap between the 2022 WHO and ICC classification for MDS. A modified Delphi P
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Xu, Qi, and Jeanne Kowalski-Muegge. "Mutation-site localized non-B DNA burden and survival heterogeneity in early-stage pancreatic cancer." Journal of Clinical Oncology 41, no. 16_suppl (2023): 4166. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.4166.

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4166 Background: Pancreatic cancer is a highly aggressive disease with a poor prognosis, and one in which most measure of genomic instability (e.g., tumor mutation burden (TMB), fraction of genome altered (FGA)) have thus far, not proven informative in differentiating survival. Non-B DNA are alternative DNA forms that deviate from the canonical B-DNA structure with potential to increase susceptibility to mutations, leading to the development of cancer. The role of non-B in pancreatic cancer has not been fully explored. Herein, we investigate the relationship between gene mutation sites co-loca
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Meier, Patricia Stutzmann, Silvia Utz, Suzanne Aebi, and Kathrin Mühlemann. "Low-Level Resistance to Rifampin in Streptococcus pneumoniae." Antimicrobial Agents and Chemotherapy 47, no. 3 (2003): 863–68. http://dx.doi.org/10.1128/aac.47.3.863-868.2003.

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ABSTRACT Rifampin is recommended for combination therapy of meningitis due to β-lactam-resistant Streptococcus pneumoniae. High-level rifampin resistance (MIC, ≥4 mg/liter) has been mapped to point mutations in clusters I and III of rpoB of the pneumococcus. The molecular basis of low-level resistance (MICs, ≥0.5 and <4 mg/liter) was analyzed. Spontaneous mutants of clinical pneumococcal isolates were selected on Columbia sheep blood agar plates containing rifampin at 0.5, 4, 10, or 50 mg/liter. Low-level resistance could be assigned to mutations in cluster II (I545N, I545L). Sensitive (MIC
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Svicher, Valentina, Tobias Sing, Maria Mercedes Santoro, et al. "Involvement of Novel Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutations in the Regulation of Resistance to Nucleoside Inhibitors." Journal of Virology 80, no. 14 (2006): 7186–98. http://dx.doi.org/10.1128/jvi.02084-05.

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ABSTRACT We characterized 16 additional mutations in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) whose role in drug resistance is still unknown by analyzing 1,906 plasma-derived HIV-1 subtype B pol sequences from 551 drug-naïve patients and 1,355 nucleoside RT inhibitor (NRTI)-treated patients. Twelve mutations positively associated with NRTI treatment strongly correlated both in pairs and in clusters with known NRTI resistance mutations on divergent evolutionary pathways. In particular, T39A, K43E/Q, K122E, E203K, and H208Y clustered with the nucleoside analogue mu
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Dissertations / Theses on the topic "Cluster mutation"

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Warkentin, Matthias. "Exchange Graphs via Quiver Mutation." Doctoral thesis, Universitätsbibliothek Chemnitz, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-153172.

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Inspired by Happel's question, whether the exchange graph and the simplicial complex of tilting modules over a quiver algebra are independent from the multiplicities of multiple arrows in the quiver, we study quantitative aspects of Fomin and Zelevinsky's quiver mutation rule. Our results turn out to be very useful in the mutation-infinite case for understanding combinatorial structures as the cluster exchange graph or the simplicial complex of tilting modules, which are governed by quiver mutation. Using a class of quivers we call forks we can show that any such quiver yields a tree in the ex
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Scott, J., I. Reiten, O. Iyama, and A. B. Buan. "Cluster structures for 2-Calabi-Yau categories and unipotent groups." Cambridge University Press, 2009. http://hdl.handle.net/2237/14400.

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Qian, Zheng. "Analysis of DNA damage induced by 2-hydroxy amino-1-methyl-6-phenyl-imidazol [4,5-b] pyridine (N-OH-PHIP) in the mutation cluster region of the human APC gene." Available to US Hopkins community, 2002. http://wwwlib.umi.com/dissertations/dlnow/3068198.

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Tran, Thi thanh tam. "Comparative and functional genome analysis of Acidithiobacillus bacteria." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4060.

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Les bactéries acidophiles du genre Acidithiobacillus joue un rôle important dans les activités industrielles de récupération des métaux au sein des sites miniers. Dans cette thèse, la séquence du génome de la bactérie psychro-tolerante Acidithiobacillus ferrivorans CF27 a été re-séquencée. L’analyse comparative du génome de CF27 et des autres bactéries du genre Acidithiobacillus a permis de montrer: (i) une synthénie conservée entre 2 clusters de tRNAs trouvés dans les génomes de At. ferrivorans CF27 et At. ferrooxidans ATCC 23270, et qui ont contribué à la redondance génique des tRNAs chez ce
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Chevallet, Mireille. "Étude du rôle structural et fonctionnel de la sous-unité NUO I de la NADH:ubiquinone oxydoréductase Rhodobacter capsulatus." Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10181.

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La nadh ubiquinone oxydoreductase ou complexe i est le premier element de la chaine respiratoire mitochondriale. Cette enzyme, dont le deficit est associe a plusieurs pathologies humaines, est un element essentiel du metabolisme energetique. Sa taille, sa localisation, sa complexite, le fait qu'elle soit codee a la fois par le genome mitochondrial et le genome nucleaire rendent son etude difficile. Pour ces raisons un modele bacterien a ete etudie : la nadh oxydoreductase de rhodobacter capsulatus qui ne contient que 14 sous-unites. La sous-unite nuo i du complexe i bacterien est remarquableme
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Lawson, John William. "On the combinatorics of quivers, mutations and cluster algebra exchange graphs." Thesis, Durham University, 2017. http://etheses.dur.ac.uk/12095/.

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Over the last 20 years, cluster algebras have been widely studied, with numerous links to different areas of mathematics and physics. These algebras have a cluster structure given by successively mutating seeds, which can be thought of as living on some graph or tree. In this way one can use various combinatorial tools to discover more about these cluster structures and the cluster algebras themselves. This thesis considers some of the combinatorics at play here. Mutation-finite quivers have been classified, with links to triangulations of surfaces and semi-simple Lie algebras, while comparati
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Gratz, Sira Helena [Verfasser]. "From finite to infinite : cluster algebras as colimits, and mutating torsion pairs in discrete cluster categrories / Sira Helena Gratz." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover (TIB), 2015. http://d-nb.info/1075261287/34.

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Tanaka, Daisuke. "GCKR mutations in Japanese families with clustered type 2 diabetes." Kyoto University, 2011. http://hdl.handle.net/2433/142543.

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Holler, Julia Pia Natascha. "Art und Häufigkeit von Mutationen im Wachstumshormon-Gen-Cluster bei Patienten mit einem isolierten Wachstumshormonmangel /." Giessen : VVB Laufersweiler, 2007. http://d-nb.info/987804154/04.

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Beka, Sylvia Enobong. "The genomics of Type 1 Diabetes susceptibility regions and effect of regulatory SNPs." Thesis, University of Hertfordshire, 2016. http://hdl.handle.net/2299/17200.

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Human complex diseases, like Diabetes and Cancer, affect many people worldwide today. Despite existing knowledge, many of these diseases are still not preventable. Complex diseases are known to be caused by a combination of genetic factors, as well as environmental and life style factors. The scope of this investigation covered the genomics of Type 1 Diabetes (T1D). There are 49 human genomic regions that are known to carry markers (disease-associated single nucleotide mutations) for T1D, and these were extensively studied in this research. The aim was to find out in how far this disease may b
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Books on the topic "Cluster mutation"

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Sadleir, Lynette G., Jozef Gecz, and Ingrid E. Scheffer. Epilepsies That Occur Predominantly in Girls. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0041.

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Availability of DNA sequencing has led to an increase in the number of children being identified with mutations in specific genes in specific epilepsy phenotypes. The presence of mutations that cause epilepsy only in females is one of the discoveries revealed in the sequencing era. Mutations in PCDH19 and CDKL5 are distinctive and identifiable forms of female-only epilepsy, and clinicians should consider PCDH19 in normal girls presenting with clusters of afebrile or febrile seizures in the first 3 years of life, and CDKL5 in girls or boys presenting with severe developmental delay within the f
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Zhang, Marina, Mark Dodgson, and David Gann. Demystifying China's Innovation Machine. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198861171.001.0001.

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China’s extraordinary economic development is explained in large part by the way it innovates. This book explains how it innovates, which has important implications not only for China but also for the rest of the world. Contrary to widely held views, China’s innovation machine is not created and controlled by an all-powerful government. Instead, it is a complex, interdependent system composed of hundreds of millions of elements, involving bottom-up innovation driven by innovators and entrepreneurs and highly pragmatic and adaptive top-down policy. Using case studies of leading firms and indust
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Book chapters on the topic "Cluster mutation"

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Jankulovska, Mirjana, Sonja Ivanovska, Ljupcho Jankuloski, Mile Markoski, Biljana Kuzmanovska, and Dane Boshev. "Evaluation of advanced wheat mutant lines for food and feed quality." In Mutation breeding, genetic diversity and crop adaptation to climate change. CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0021.

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Abstract The main goals of this study were to evaluate the agronomic performance of wheat mutant lines; to detect the effect of genotype, location and different fertilizer levels on analysed traits; to assess seed and feed quality; and to select best performing mutant lines for dual-purpose growing. Ten wheat mutant lines were sown on two locations in Macedonia, for evaluation of their agronomic performance. At both locations, grain yield, straw mass, harvest index, nitrogen use efficiency, nitrogen and protein content in seed and straw, neutral detergent fibre and acid detergent fibre in the
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Rath, Soumya Lipsa, Chiranjeev Sinha, Sri Lakshmi Noumi Priya Kasturi, Smaranika Mohapatra, and Kusumlata Jain. "An Unsupervised Clustering Algorithm to Cluster the New SARS-CoV-2 Virus Mutation." In Innovations in Computer Science and Engineering. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-8987-1_19.

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Huai, Haiying, and R. C. Woodruff. "Clusters of new identical mutants and the fate of underdominant mutations." In Mutation and Evolution. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5210-5_37.

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Selby, P. B. "Discovery of numerous clusters of spontaneous mutations in the specific-locus test in mice necessitates major increases in estimates of doubling doses." In Mutation and Evolution. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5210-5_36.

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Bhattacharyya, S. P., and Kanchan Sarkar. "Adaptive Mutation-Driven Search for Global Minima in 3D Coulomb Clusters: A New Method with Preliminary Applications." In Advances in Intelligent Systems and Computing. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1602-5_129.

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Nerede, Helin, and Menduh Oruc. "Aspiration Pneumonia in Children." In Pediatric Chest Infection. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359463.14.

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Idiopathic pulmonary fibrosis is characterized by an aberrant wound healing response following lung injury, leading to excessive fibroblast proliferation and extracellular matrix deposition. Fibroblasts and myofibroblasts play a central role in the disease process. They proliferate abnormally and produce collagen and other matrix proteins, resulting in fibrosis. Epithelial-mesenchymal transition where epithelial cells transform into mesenchymal cells, contributes to the pool of fibroblasts in the fibrotic lung. Mutations in genes related to telomere maintenance (TERT, TERC) and surfactant prot
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Raffeld, M., T. Yano, A. T. Hoang, et al. "Clustered Mutations in the Transcriptional Activation Domain of Myc in 8q24 Translocated Lymphomas and their Functional Consequences." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79275-5_31.

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Olcay, Mahmut. "Viral Pneumonia in Children." In Pediatric Chest Infection. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359463.15.

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Abnormal wound healing of idiopathic pulmonary fibrosis is characterized by an inappropriate wound healing response following lung injury, leading to excessive proliferation of fibroblasts and deposition of extracellular matrix proteins. Fibroblasts and myofibroblasts are central players in the fibrotic process, these cells proliferate and produce large amounts of collagen and other matrix components, contributing to the stiffening of lung tissue. Epithelial-mesenchymal transition of epithelial cells transform into mesenchymal cells, adding to the fibroblast population and promoting fibrosis.
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Rabon, E. C., S. J. Rulli, and E. V. Skripnikov. "The Effect of Mutations Within a Cluster of Homologous Amino Acids Present in the M5, M6 and M8 Transmembrane Regions of the H,K-ATPase." In Mechanisms and Consequences of Proton Transport. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0971-4_8.

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"MCR (mutation cluster region)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_10007.

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Conference papers on the topic "Cluster mutation"

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Suhaimi, Nur Suhailayani, Siti Nur Kamaliah, Norazam Arbin, and Zalinda Othman. "Optimizing Cluster of Questions by Using Dynamic Mutation in Genetic Algorithm." In 2015 3rd International Conference on Artificial Intelligence, Modelling & Simulation (AIMS). IEEE, 2015. http://dx.doi.org/10.1109/aims.2015.81.

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Sun, Tsung-ying, Chan-cheng Liu, Sheng-ta Hsieh, Chun-ling Lin, and Kan-yuan Lee. "Cluster-based Adaptive Mutation Mechanism To Improve the Performance of Genetic Algorithm." In 2006 6th International Conference on Intelligent Systems Design and Applications. IEEE, 2006. http://dx.doi.org/10.1109/isda.2006.123.

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Lin, E. E. "Cluster mechanism of stochastic kinetics of mutation formation protein nanoparticles and mesoobjects." In Наука России: Цели и задачи. LJournal, 2019. http://dx.doi.org/10.18411/sr-10-04-2019-68.

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Zhang, Jiapei, Wei Li, Zhangcan Yang, and Yingzhao He. "Molecular Dynamics Simulation of Diffusion and Aggregation Behavior of Helium in Tungsten Bulk Materials." In ASME 2019 6th International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/mnhmt2019-3947.

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Abstract Controlled thermonuclear fusion is a promising project. If it can be realized, it will certainly replace fossil fuels and solve the problem of energy exhaustion facing humanity. The fusion reaction fuel is a light core, which can be extracted from sea water. The source is very rich, and the fusion reaction of hydrogen and its isotopes is not radioactive, so the fusion energy can be efficient, cheap and clean. At present, the realization of this technology still faces many difficult problems that have not been overcome. The Tokamak device is the most promising device for realizing the
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Rafikova, O., M. Niihori, C. A. Eccles, M. Vasilyev, and R. Rafikov. "Pulmonary Hypertension and Metabolic Disease in Rats with Human Mutation in Fe-S Cluster Scaffold Protein NFU1." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5870.

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Arifah, Nur, Laila Hanum, and Muharni Muharni. "DNA Mutation of Rc Gene and the Phenotype of Aleurone and Pericarp of Local Red Rice from South Sumatera." In International Conference on Industrial Sciences, Engineering and Technology toward Digital Era 2023. Trans Tech Publications Ltd, 2024. http://dx.doi.org/10.4028/p-2nbp2i.

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The red color of red rice pericarp and aleurone is regulated by proanthocyanidin protein. Proanthocyanidin protein was encoded by partial sequence of Rc gene. The mutation from DNA sequence would give divers phenotype in pericarp and aleurone. This study used four sample of local red rice (Keli Rejo, Sumber Jaya, Cahya Tani, Sirah Pulau Padang) from South Sumatra as genetic sources and specific primers (RC12) were used to encode Proanthocyanidin protein on local red rice. This research was conducted at the Genetic and Biotechnology Laboratory of Biology Department, Faculty of Mathematics and N
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Cruz, Robinson Crusoe da, and Marcelo Medeiros Eler. "Using a cluster analysis method for grouping classes according to their inferred testability: An investigation of CK metrics, code coverage and mutation score." In 2017 36th International Conference of the Chilean Computer Science Society (SCCC). IEEE, 2017. http://dx.doi.org/10.1109/sccc.2017.8405117.

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Fratavchan, Valerіi, Tonia Fratavchan, and Victor Ababii. "Pseudo Genetic Algorithm of Clustering For Linear and Ellipsoidal Clusters." In 12th International Conference on Electronics, Communications and Computing. Technical University of Moldova, 2022. http://dx.doi.org/10.52326/ic-ecco.2022/cs.07.

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This article considers the method of clustering in the problems of pattern recognition when studying with a teacher in the case of n-dimensional numerical features. Clusters of linear and ellipsoidal forms that are optimal in the number of errors are created by the method of pseudo genetic algorithm. The pseudo genetic algorithm has a simplified procedure for performing mutation and crossover operations.
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"Detecting Interacting Mutation Clusters in HIV-1 Drug Resistance." In International Conference on Bioinformatics Models, Methods and Algorithms. SciTePress - Science and and Technology Publications, 2013. http://dx.doi.org/10.5220/0004238800340043.

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Andersson, Erik, Rebecca Hsieh, Howard Szeto, Roshanak Farhoodi, Nurit Haspel, and Filip Jagodzinski. "Assessing how multiple mutations affect protein stability using rigid cluster size distributions." In 2016 IEEE 6th International Conference on Computational Advances in Bio and Medical Sciences (ICCABS). IEEE, 2016. http://dx.doi.org/10.1109/iccabs.2016.7802777.

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Reports on the topic "Cluster mutation"

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Eshed, Y., and Z. B. Lippman. Fine tuning the shoot and inflorescence architectures for improved tomato yield. United States-Israel Binational Agricultural Research and Development Fund, 2022. http://dx.doi.org/10.32747/2022.8134148.bard.

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In this project, we are determining the contribution of different types of variations, in gene function and in gene regulation, to altered shoot architecture first, and to field performance in the next stage. We are using tomato as a target, but also as a model for many other crops. Our focus is on two different components of yield associated traits - shoot architecture and organization of the inflorescence. Our focus was on two types of regulators; 1) genes involved in florigen - antiflogen balance and the way they impact the shoot, and 2) genes involved in inflorescence branching and it this
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Ohad, Itzhak, and Himadri Pakrasi. Role of Cytochrome B559 in Photoinhibition. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7613031.bard.

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The aim of this research project was to obtain information on the role of the cytochrome b559 in the function of Photosystem-II (PSII) with special emphasis on the light induced photo inactivation of PSII and turnover of the photochemical reaction center II protein subunit RCII-D1. The major goals of this project were: 1) Isolation and sequencing of the Chlamydomonas chloroplast psbE and psbF genes encoding the cytochrome b559 a and b subunits respectively; 2) Generation of site directed mutants and testing the effect of such mutation on the function of PSII under various light conditions; 3)
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