Academic literature on the topic 'Cocrystallization studies'

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Journal articles on the topic "Cocrystallization studies"

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Ren, Zhongqi, Xinjian Chen, Guojia Yu, Yinglei Wang, Bin Chen, and Zhiyong Zhou. "Molecular simulation studies on the design of energetic ammonium dinitramide co-crystals for tuning hygroscopicity." CrystEngComm 22, no. 31 (2020): 5237–44. http://dx.doi.org/10.1039/d0ce00602e.

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Timofeeva, Tatiana, Sofia Antal, Sergiu Draguta, Karla Ordonez, Raul Castaneda, and Evgeniya Leonova. "Cocrystallization of acetaminophen and glutaric acid with different coformers." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C1028. http://dx.doi.org/10.1107/s2053273314089712.

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Recently cocrystallization became a popular tool for crystal engineering that allows, for instance, improving properties of pharmaceutical materials, creating new materials for nonlinear optical applications and solar cell technologies. To attract students to crystallographic studies we carried out project that included crystal growth of two series of cocrystals with acetaminophen and with dicarbonic glutaric acid. We attempted cocrystallization of acetaminophen with more than ten different coformers which gave no cocrystals or salts. However, as a result of cocrystallization we obtained new p
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Manoj, K., Rui Tamura, Hiroki Takahashi, and Hirohito Tsue. "Crystal engineering of homochiral molecular organization of naproxen in cocrystals and their thermal phase transformation studies." CrystEngComm 16, no. 26 (2014): 5811–19. http://dx.doi.org/10.1039/c3ce42415d.

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Duan, Binghui, Yuanjie Shu, Ning Liu, et al. "Comparative studies on structure, sensitivity and mechanical properties of CL-20/DNDAP cocrystal and composite by molecular dynamics simulation." RSC Advances 8, no. 60 (2018): 34690–98. http://dx.doi.org/10.1039/c8ra07387b.

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SOLOMON, CRISTINA. "PREFORMULATION STUDIES OF TABLETS CONTAINING RIVAROXABAN – NIACINAMIDE COCRYSTALLIZATION COMPOUNDS." FARMACIA 73, no. 3 (2025): 706–12. https://doi.org/10.31925/farmacia.2025.3.17.

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Xu, Jia, Qin Shi, Yanan Wang, et al. "Recent Advances in Pharmaceutical Cocrystals: A Focused Review of Flavonoid Cocrystals." Molecules 28, no. 2 (2023): 613. http://dx.doi.org/10.3390/molecules28020613.

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Cocrystallization is currently an attractive technique for tailoring the physicochemical properties of active pharmaceutical ingredients (APIs). Flavonoids are a large class of natural products with a wide range of beneficial properties, including anticancer, anti-inflammatory, antiviral and antioxidant properties, which makes them extensively studied. In order to improve the properties of flavonoids, such as solubility and bioavailability, the formation of cocrystals may be a feasible strategy. This review discusses in detail the possible hydrogen bond sites in the structure of APIs and the h
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Asojo, Oluwatoyin Ajibola, Oluyomi Adebola Asojo, Michelle N. Ngamelue, Kohei Homma, and Oksana Lockridge. "Cocrystallization studies of full-length recombinant butyrylcholinesterase (BChE) with cocaine." Acta Crystallographica Section F Structural Biology and Crystallization Communications 67, no. 4 (2011): 434–37. http://dx.doi.org/10.1107/s1744309111004805.

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Hiendrawan, Stevanus, Bambang Veriansyah, and Raymond R. Tjandrawinata. "SOLID-STATE PROPERTIES AND SOLUBILITY STUDIES OF NOVEL PHARMACEUTICAL COCRYSTAL OF ITRACONAZOLE." International Journal of Applied Pharmaceutics 10, no. 5 (2018): 97. http://dx.doi.org/10.22159/ijap.2018v10i5.26663.

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Objective: Pharmaceutical cocrystal is a promising method to improve the solubility of active pharmaceutical ingredients (APIs). Itraconazole (ITZ) is a BCS class II antifungal drug with poor aqueous solubility, therefore an attempt was made to improve the solubility of ITZ using cocrystallization technique. In this work, six novel pharmaceutical cocrystals of ITZ with various coformers, including 4-hydroxybenzoic acid (4HBA), trans-cinnamic acid (TCA), suberic acid (SUB), sebacic acid (SBC), 1-hydroxy-2-naphthoic acid (1H2N), and benzamide (BZD) were prepared.Methods: ITZ cocrystals was prepa
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Shahbaz, Muhammad, Umair Ahmed Khan, M. Iqbal Chaudhary, and Sammer Yousuf. "A new bioactive cocrystal of coumarin-3-carboxylic acid and thiourea: detailed structural features and biological activity studies." Acta Crystallographica Section C Structural Chemistry 78, no. 3 (2022): 192–200. http://dx.doi.org/10.1107/s205322962200081x.

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Cocrystallization is a phenomenon widely used to enhance the biological and physicochemical properties of active pharmaceutical ingredients (APIs). The present study deals with the synthesis of a cocrystal of coumarin-3-carboxylic acid (2-oxochromene-3-carboxylic acid, C10H6O4), a synthetic analogue of the naturally occurring antioxidant coumarin, with thiourea (CH4N2S) using the neat grinding method. The purity and homogeneity of the coumarin-3-carboxylic acid–thiourea (1/1) cocrystal was confirmed by single-crystal X-ray diffraction, FT–IR analysis and thermal stability studies based on diff
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Mikheev, N. B., I. V. Melikhov, and S. A. Kulyukhin. "Cocrystallization processes in physicochemical studies of radioactive elements in various media." Radiochemistry 49, no. 6 (2007): 549–60. http://dx.doi.org/10.1134/s106636220706001x.

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Dissertations / Theses on the topic "Cocrystallization studies"

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Ganduri, Ramesh. "Cocrystallization Studies Extending from Small Molecules to Proteins: a) Cocrystals, Salts and Eutectics, b) Chemical, Structural and Biological Evaluation of Anthrapyrazolones as Inhibitors of JNK proteins." Thesis, 2018. https://etd.iisc.ac.in/handle/2005/5363.

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In summary, we have designed and synthesized three halogenated derivatives of 1,9- pyrazoloanthrone. The involvement of halogen bonding provides highly directional interactions in the binding pocket and hence demonstrates improved inhibitory activity. Among the three halogenated derivatives of 1,9-pyrazoloanthrone, R3 exhibits the most specific inhibition of JNKs activity at significantly lower concentrations (1M) compared to R1, R2 and SP600125 with no off-target effects on other kinases such as p38 and ERK1/2. Further, R3 being a potent and specific inhibitor of JNKs, regulates LPStri
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Seera, Raviteja. "The Crystal Form Diversity From Cocrystals To Eutectics: Design, Synthesis, Production And Property Evaluation." Thesis, 2020. https://etd.iisc.ac.in/handle/2005/4939.

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This thesis aims to design and synthesize organic molecules to generate properties like SHG, ferroelectric and dielectric. In continuation, we have done cocrystallization studies to study the trend in between the two extremums and also evaluated the particle size as well as the particle size distribution and paved the way for the bulk production in quick time using a thermal inkjet printer. Also, we have studied and analyzed the priorities of hydrogen bond and halogen bond formation involving organic fluorine. Chapter 1 discusses the multi-component adducts of benzoic acid with differen
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