Log in

Relevant bibliographies by topics / Conserved Regulatory Sequences

Contents

Journal articles
Dissertations / Theses
Book chapters
Conference papers
Reports

Academic literature on the topic 'Conserved Regulatory Sequences'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Conserved Regulatory Sequences.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Conserved Regulatory Sequences"

1

Skowronska-Krawczyk, D., F. Chiodini, M. Ebeling, et al. "Conserved regulatory sequences in Atoh7 mediate non-conserved regulatory responses in retina ontogenesis." Development 136, no. 22 (2009): 3767–77. http://dx.doi.org/10.1242/dev.033449.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Ciren, Danielle, Sophia Zebell, and Zachary B. Lippman. "Extreme restructuring of cis-regulatory regions controlling a deeply conserved plant stem cell regulator." PLOS Genetics 20, no. 3 (2024): e1011174. http://dx.doi.org/10.1371/journal.pgen.1011174.

Full text

Abstract:

A striking paradox is that genes with conserved protein sequence, function and expression pattern over deep time often exhibit extremely divergent cis-regulatory sequences. It remains unclear how such drastic cis-regulatory evolution across species allows preservation of gene function, and to what extent these differences influence how cis-regulatory variation arising within species impacts phenotypic change. Here, we investigated these questions using a plant stem cell regulator conserved in expression pattern and function over ~125 million years. Using in-vivo genome editing in two distantly

APA, Harvard, Vancouver, ISO, and other styles

3

Britton, Candace S., Trevor R. Sorrells, and Alexander D. Johnson. "Protein-coding changes preceded cis-regulatory gains in a newly evolved transcription circuit." Science 367, no. 6473 (2020): 96–100. http://dx.doi.org/10.1126/science.aax5217.

Full text

Abstract:

Changes in both the coding sequence of transcriptional regulators and in the cis-regulatory sequences recognized by these regulators have been implicated in the evolution of transcriptional circuits. However, little is known about how they evolved in concert. We describe an evolutionary pathway in fungi where a new transcriptional circuit (a-specific gene repression by the homeodomain protein Matα2) evolved by coding changes in this ancient regulator, followed millions of years later by cis-regulatory sequence changes in the genes of its future regulon. By analyzing a group of species that has

APA, Harvard, Vancouver, ISO, and other styles

4

Hardison, R. "Conserved noncoding sequences are reliable guides to regulatory elements." Trends in Genetics 16, no. 9 (2000): 369–72. http://dx.doi.org/10.1016/s0168-9525(00)02081-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Adams, Mark D. "Conserved sequences and the evolution of gene regulatory signals." Current Opinion in Genetics & Development 15, no. 6 (2005): 628–33. http://dx.doi.org/10.1016/j.gde.2005.09.004.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Cruz, Maria Araceli Diaz, Dan Lund, Ferenc Szekeres, Sandra Karlsson, Maria Faresjö, and Dennis Larsson. "Cis-regulatory elements in conserved non-coding sequences of nuclear receptor genes indicate for crosstalk between endocrine systems." Open Medicine 16, no. 1 (2021): 640–50. http://dx.doi.org/10.1515/med-2021-0264.

Full text

Abstract:

Abstract Nuclear receptors (NRs) are ligand-activated transcription factors that regulate gene expression when bound to specific DNA sequences. Crosstalk between steroid NR systems has been studied for understanding the development of hormone-driven cancers but not to an extent at a genetic level. This study aimed to investigate crosstalk between steroid NRs in conserved intron and exon sequences, with a focus on steroid NRs involved in prostate cancer etiology. For this purpose, we evaluated conserved intron and exon sequences among all 49 members of the NR Superfamily (NRS) and their relevan

APA, Harvard, Vancouver, ISO, and other styles

7

Yocca, Alan E., Zefu Lu, Robert J. Schmitz, Michael Freeling, and Patrick P. Edger. "Evolution of Conserved Noncoding Sequences in Arabidopsis thaliana." Molecular Biology and Evolution 38, no. 7 (2021): 2692–703. http://dx.doi.org/10.1093/molbev/msab042.

Full text

Abstract:

Abstract Recent pangenome studies have revealed a large fraction of the gene content within a species exhibits presence–absence variation (PAV). However, coding regions alone provide an incomplete assessment of functional genomic sequence variation at the species level. Little to no attention has been paid to noncoding regulatory regions in pangenome studies, though these sequences directly modulate gene expression and phenotype. To uncover regulatory genetic variation, we generated chromosome-scale genome assemblies for thirty Arabidopsis thaliana accessions from multiple distinct habitats an

APA, Harvard, Vancouver, ISO, and other styles

8

Taher, L., D. M. McGaughey, S. Maragh, et al. "Genome-wide identification of conserved regulatory function in diverged sequences." Genome Research 21, no. 7 (2011): 1139–49. http://dx.doi.org/10.1101/gr.119016.110.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

LE, SHU-YUN, JACOB V. MAIZEL, and KAIZHONG ZHANG. "FINDING CONSERVED WELL-ORDERED RNA STRUCTURES IN GENOMIC SEQUENCES." International Journal of Computational Intelligence and Applications 04, no. 04 (2004): 417–30. http://dx.doi.org/10.1142/s1469026804001409.

Full text

Abstract:

Recent advances in RNA studies show that the well-ordered, structured RNAs perform a broad functions in various biological mechanisms. Included among these functions are regulations of gene expression at multiple levels by diversified ribozymes and various RNA regulatory elements. The discovered microRNAs (miRNAs) with a distinct stem-loops are a new class of RNA regulatory elements. The prediction of those well-ordered folding sequences (WFS) associated with the RNA regulatory elements in genomic sequences is very helpful for our understandings of RNA-based gene regulations. We present here a

APA, Harvard, Vancouver, ISO, and other styles

10

Vikkula, M., M. Metsäranta, A. C. Syvänen, L. Ala-Kokko, E. Vuorio, and L. Peltonen. "Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse." Biochemical Journal 285, no. 1 (1992): 287–94. http://dx.doi.org/10.1042/bj2850287.

Full text

Abstract:

Transcription of the type-II procollagen gene (COL2A1) is very specifically restricted to a limited number of tissues, particularly cartilages. In order to identify transcription-control motifs we have sequenced the promoter region and the first intron of the human and mouse COL2A1 genes. With the assumption that these motifs should be well conserved during evolution, we have searched for potential elements important for the tissue-specific transcription of the COL2A1 gene by aligning the two sequences with each other and with the available rat type-II procollagen sequence for the promoter. Wi

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Conserved Regulatory Sequences"

1

Azevedo, Joana Isabel Carvalho. "Txnip has a conserved non-coding regulatory sequence and regulates Meth-induced neuronal effects." Master's thesis, 2020. https://hdl.handle.net/10216/130821.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Azevedo, Joana Isabel Carvalho. "Txnip has a conserved non-coding regulatory sequence and regulates Meth-induced neuronal effects." Dissertação, 2020. https://hdl.handle.net/10216/130821.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Conserved Regulatory Sequences"

1

Trutschl, Marjan, Phillip C. S. R. Kilgore, Rona S. Scott, Christine E. Birdwell, and Urška Cvek. "Detection and Employment of Biological Sequence Motifs." In Big Data Analytics in Bioinformatics and Healthcare. IGI Global, 2015. http://dx.doi.org/10.4018/978-1-4666-6611-5.ch005.

Full text

Abstract:

Biological sequence motifs are short nucleotide or amino acid sequences that are biologically significant and are attractive to scientists because they are usually highly conserved and result in structural and regulatory implications. In this chapter, the authors show practical applications of these data, followed by a review of the algorithms, techniques, and tools. They address the nature of motifs and elucidate on several methods for de novo motif discovery, covering the algorithms based on Gibbs sampling, expectation maximization, Bayesian inference, covariance models, and discriminative l

APA, Harvard, Vancouver, ISO, and other styles

2

Pfahl, Magnus, Xiao-Kun Zhang, Jürgen M. Lehmann, Matthias Husmann, Gerhart Graupner, and Birgit Hoffmann. "Molecular mechanisms of retinoic acid action." In Retinoids in Normal Development and Teratogenesis. Oxford University PressOxford, 1992. http://dx.doi.org/10.1093/oso/9780198547709.003.0004.

Full text

Abstract:

Abstract The multitude of essential biological processes regulated by the vitamin A derivative retinoic acid (RA) and synthetic analogues (retinoids) (reviewed in Lotan 1980; Sporn et al. 1984), combined with the many beneficial and undesirable side-effects (Lippman et al. 1987) associated with retinoid therapies, suggest the existence of a highly complex regulatory mechanism. How can a single substance —RA—regulate a large diversity of programmes and, in addition, provoke at times opposite effects, e.g. during limb morphogenesis, where low concentrations of RA can lead to duplications of digi

APA, Harvard, Vancouver, ISO, and other styles

3

Matzke, Marjori A., and Antonius J. M. Matzke. "Homology-dependent gene silencing in transgenic plants and related phenomena in other eukaryotes." In Nuclear Organization, Chromatin Structure, and Gene Expression. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198549239.003.0016.

Full text

Abstract:

Abstract Higher eukaryotic genomes contain substantial amounts of repetitive DNA. What limitations, if any, are placed on the quantity and distribution of repetitive sequences and do these parameters in tum influence gene expression? Some contend that non-genie repeated DNA sequences, which constitute ca. 30 per cent of mammalian genomes and 15—90 per cent of flowering plant genomes, are mostly non-functional ‘junk’ (John and Miklos 1988), while others suggest that they have essential structural and/or regulatory roles (Davidson and Britten 1979; Smyth 1991; see Chapter 13). In plants large di

APA, Harvard, Vancouver, ISO, and other styles

4

Niikura, Yohei, and Katsumi Kitagawa. "E3 Ligase for CENP-A (Part 2)." In Hydrolases [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102486.

Full text

Abstract:

Centromeric CENP-A, a variant of histone H3, plays a central role in proper chromosome segregation and its function is highly conserved among different species. In most species with regional centromeres, an active centromere relies not on defined DNA sequences, but on the presence of CENP-A proteins in centromeric nucleosomes. CENP-A is proposed to be the non-DNA indicator (epigenetic mark) that defines proper centromere assembly and function. Recently, many post-translational modifications (PTMs) of CENP-A and their functions have been reported. They revealed the importance of the functions o

APA, Harvard, Vancouver, ISO, and other styles

5

Foiani, Marco, Giordano Liberi, Simonetta Piatti, and Paolo Plevani. "Saccharomyces cerevisiae as a model system to study DNA replication." In Eukaryotic DNA Replication. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780199636815.003.0008.

Full text

Abstract:

Abstract The budding yeast Saccharomyces cerevisiae represents a powerful tool to study DNA replication and the cell cycle regulatory pathways controlling entry into, and progression through S phase. In fact, the availability of the complete sequence of the S. cerevisiae genome, the identification of several DNA replication genes, together with the possibility of combining molecular genetic tools with classical techniques of genetics, biochemistry, and cell biology, make this system particularly useful to improve our knowledge of the DNA replication process at the molecular level. Moreover, by

APA, Harvard, Vancouver, ISO, and other styles

6

Petrou, Petros P., and Peter Gruss. "Introduction to Paired-Box Genes." In Inborn Errors Of Development. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195306910.003.0083.

Full text

Abstract:

Abstract The paired box–containing (Pax) genes comprise a family of highly conserved transcriptional regulators that play essential roles in diverse processes of early animal development and cell-fate speci)cation. The discovery of their characteristic feature, the paired box, dates back to the extensive systematic mutagenesis screen performed in the fruit %y Drosophila melanogaster (Nüsslein-Volhard and Wieschaus, 1980). The isolation and subsequent cloning of the genes affected by mutations, resulting in defects in primary body patterning and segmentation, revealed that many of them encoded

APA, Harvard, Vancouver, ISO, and other styles

7

Niikura, Yohei, and Katsumi Kitagawa. "E3 Ligase for CENP-A (Part 1)." In Hydrolases [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101712.

Full text

Abstract:

CENP-A is a centromere-specific histone H3 variant that is required to ensure kinetochore assembly for proper chromosome segregation and its function is highly conserved among different species including budding yeast, Saccharomyces cerevisiae. The budding yeast Saccharomyces cerevisiae has genetically defined point centromeres, unlike other eukaryotes. Although, most eukaryotic centromeres are maintained epigenetically, currently only budding yeast S. cerevisiae centromeres are known to be genetically specified by DNA sequence, The small size and sequence specificity of the budding yeast cent

APA, Harvard, Vancouver, ISO, and other styles

8

Dahl, Richard, Renee D. Hackenmiller,, and M. Celeste Simon. "Ets Transcription Factor Mutations and Hematopoiesis." In Hematopoiesis. Oxford University PressNew York, NY, 2001. http://dx.doi.org/10.1093/oso/9780195124507.003.0035.

Full text

Abstract:

Abstract The Ets family of transcription factors consists of a large number of winged helix-loop-helix DNA-binding proteins. Members of the Ets family are related by a high degree of sequence identity within the DNA-binding domain (ETS domain), which recognizes purine-rich DNA motifs centered around the core nucleotides GGAA/T (Karim et al., 1990). The Ets proteins are highly conserved through evolution and are important regulators of development in flies, worms, and mammals. At least eight Ets proteins, including PU. I, Spi-B, Ets-1, Ets-2, Elf-1, Fli-1, TEL, and GABPcx are expressed in hemat

APA, Harvard, Vancouver, ISO, and other styles

9

Requejo-Serrano, Cristina, Julia Escudero-Feliu, Maria Ortega-Ferrer, et al. "Molecular and Functional Analysis of Soybean Allergen Proteins with a Focus on Pollen-Food Syndrome." In Agricultural Sciences. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.115283.

Full text

Abstract:

Gly m 3 and Gly m 4 are major soybean food allergens, causing birch pollen cross-allergic reactions, particularly with Bet v 1 and Bet v 2. These allergens can mediate anaphylactic reactions; however, the causative factors are still unknown. The goals of this comparative study are to characterize (A) the structural functionality of Gly m allergens of Glycine max and Bet v allergens of Betula pendula form birch, with a focus on their immunological properties, and (B) the molecular mechanisms of cross-allergenicity involved in pollen-food syndrome. This was achieved by extensive analysis using d

APA, Harvard, Vancouver, ISO, and other styles

10

"Paddlefish: Ecological, Aquacultural, and Regulatory Challenges of Managing a Global Resource." In Paddlefish: Ecological, Aquacultural, and Regulatory Challenges of Managing a Global Resource, edited by Steven R. Fain. American Fisheries Society, 2019. http://dx.doi.org/10.47886/9781934874530.ch8.

Full text

Abstract:

<i>Abstract</i>.—With the break-up of the Soviet Union in 1991, and the unhalting collapse of the Caspian Sea sturgeon fisheries from desperate management policies to maintain production, law enforcement investigators in the U.S. encountered increased poaching of Paddlefish <i>Polyodon spathula</i> caviar throughout the Mississippi River basin. The steady rise of caviar prices has encouraged the illegal, unreported, and unregulated (IUU) taking of Paddlefish and the same over-harvesting that devastated the Caspian and Atlantic Sturgeon caviar fisheries of the past. Inte

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Conserved Regulatory Sequences"

1

Huber, P., J. Dalmon, M. Laurent, G. Courtois, D. Thevenon та G. Marguerie. "CHARACTERIZATION OFTHE 5’FLANKING REGION FOR THE HUMAN FIBRINOGEN β GENE". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642889.

Full text

Abstract:

Fibrinogen is coded by three separate genes located in a 50kb region of chromosome 4 and organized in a α - β - γ orientation with an inversion of the gene 3- A human genomic library was constructed using the EMBL4 phage and screened with cDNA probes coding for human fibrinogen Aα, Bβ and γ chains. Clones, covering the fibrinogen locus,were identified, and their organization was analyzed by means of hybridization and restriction mapping. Among these clones one recombinant phage containing the β gene and large 5’ and 3’ -flanking sequences was isolated.To identify the regulatory sequences Dpstr

APA, Harvard, Vancouver, ISO, and other styles

2

Zambalde, Erika Pereira, Ana Carolina Rodrigues, Rubens Silveira Lima, Enilze Maria Souza Fonseca Ribeiro, and Jaqueline Carvalho Oliveira. "TLNC-UC.147, A NOVEL LONG RNA (lncRNA) FROM AN ULTRACONSERVED REGION AS POTENTIAL BIOMARKER IN LUMINAL A BREAST CANCER." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1052.

Full text

Abstract:

Introduction: Long RNAs are non-coding RNAs with more than 200 nucleotides in length, with essential regulatory roles in several biological processes, including in breast cancer (BC). The human genome contains 481 ultraconserved regions, which are genomic stretches of over 200 base pairs conserved among humans, rats, and mice. Most of these regions are transcriptionally active (T-UCRs), and several are differentially expressed in tumors. Some T-UCRs have been functionally characterized, but few have been associated with BC. Objectives: In this study, we aimed to expand the knowledge of T-UCRs

APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Conserved Regulatory Sequences"

1

Eshed, Yuval, and John Bowman. Harnessing Fine Scale Tuning of Endogenous Plant Regulatory Processes for Manipulation of Organ Growth. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7696519.bard.

Full text

Abstract:

Background and objectives: Manipulation of plant organ growth is one of the primary reasons for the success of mankind allowing increasing amounts of food for human and livestock consumption. In contrast with the successful selection for desirable growth characteristics using plant breeding, transgenic manipulations with single genes has met limited success. While breeding is based on accumulation of many small alterations of growth, usually arise from slight changes in expression patterns, transgenic manipulations are primarily based on drastic, non-specific up-regulation or knock down of gen

APA, Harvard, Vancouver, ISO, and other styles

2

Chamovitz, Daniel, and Albrecht Von Arnim. Translational regulation and light signal transduction in plants: the link between eIF3 and the COP9 signalosome. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7696515.bard.

Full text

Abstract:

The COP9 signalosome (CSN) is an eight-subunit protein complex that is highly conserved among eukaryotes. Genetic analysis of the signalosome in the plant model species Arabidopsis thaliana has shown that the signalosome is a repressor of light dependent seedling development as mutant Arabidopsis seedlings that lack this complex develop in complete darkness as if exposed to light. These mutant plants die following the seedling stage, even when exposed to light, indicating that the COP9 signalosome also has a central role in the regulation of normal photomorphogenic development. The biochemical

APA, Harvard, Vancouver, ISO, and other styles

3

Yalovsky, Shaul, and Julian Schroeder. The function of protein farnesylation in early events of ABA signal transduction in stomatal guard cells of Arabidopsis. United States Department of Agriculture, 2002. http://dx.doi.org/10.32747/2002.7695873.bard.

Full text

Abstract:

Loss of function mutations in the farnesyltransferase β subunit gene ERA1 (enhanced response to abscisic acid), cause abscisic acid hypersensitivity in seedlings and in guard cells. This results in slowed water loss of plants in response to drought. Farnesyltransferase (PFT) catalyses the attachment of the 15-carbon isoprenoid farnesyl to conserved cysteine residues located in a conserved C-terminal domain designated CaaX box. PFT is a heterodimeric protein comprised of an a and b sununits. The a subunit is shared between PFT and geranylgeranyltransferase-I (PGGTI) which catalyses the attachem

APA, Harvard, Vancouver, ISO, and other styles

4

Ginzberg, Idit, Richard E. Veilleux, and James G. Tokuhisa. Identification and Allelic Variation of Genes Involved in the Potato Glycoalkaloid Biosynthetic Pathway. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7593386.bard.

Full text

Abstract:

Steroidal glycoalkaloids (SGAs) are secondary metabolites being part of the plant defense response. The two major SGAs in cultivated potato (Solanum tuberosum) are α-chaconine and α-solanine, which exhibit strong cellular lytic properties and inhibit acetylcholinesterase activity, and are poisonous at high concentrations for humans. As SGAs are not destroyed during cooking and frying commercial cultivars have been bred to contain low levels, and their content in tubers should not exceed 20 mg/100 g fresh weight. However, environmental factors can increase tuber SGA content above the safe level

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!