Relevant bibliographies by topics / Convergent transcription

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Convergent transcription'

Author: Grafiati
Published: 25 May 2024
Last updated: 31 July 2025

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Journal articles on the topic "Convergent transcription"

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Lin, Yunfu, Mei Leng, Ma Wan, and John H. Wilson. "Convergent Transcription through a Long CAG Tract Destabilizes Repeats and Induces Apoptosis." Molecular and Cellular Biology 30, no. 18 (2010): 4435–51. http://dx.doi.org/10.1128/mcb.00332-10.

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ABSTRACT Short repetitive sequences are common in the human genome, and many fall within transcription units. We have previously shown that transcription through CAG repeat tracts destabilizes them in a way that depends on transcription-coupled nucleotide excision repair and mismatch repair. Recent observations that antisense transcription accompanies sense transcription in many human genes led us to test the effects of antisense transcription on triplet repeat instability in human cells. Here, we report that simultaneous sense and antisense transcription (convergent transcription) initiated f
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Hobson, David J., Wu Wei, Lars M. Steinmetz, and Jesper Q. Svejstrup. "RNA Polymerase II Collision Interrupts Convergent Transcription." Molecular Cell 48, no. 3 (2012): 365–74. http://dx.doi.org/10.1016/j.molcel.2012.08.027.

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Gullerova, Monika, and Nick J. Proudfoot. "Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells." Nature Structural & Molecular Biology 19, no. 11 (2012): 1193–201. http://dx.doi.org/10.1038/nsmb.2392.

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Inagaki, Soichi, Mayumi Takahashi, Kazuya Takashima, Satoyo Oya, and Tetsuji Kakutani. "Chromatin-based mechanisms to coordinate convergent overlapping transcription." Nature Plants 7, no. 3 (2021): 295–302. http://dx.doi.org/10.1038/s41477-021-00868-3.

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Eszterhas, Susan K., Eric E. Bouhassira, David I. K. Martin, and Steven Fiering. "Transcriptional Interference by Independently Regulated Genes Occurs in Any Relative Arrangement of the Genes and Is Influenced by Chromosomal Integration Position." Molecular and Cellular Biology 22, no. 2 (2002): 469–79. http://dx.doi.org/10.1128/mcb.22.2.469-479.2002.

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ABSTRACT Transcriptional interference is the influence, generally suppressive, of one active transcriptional unit on another unit linked in cis. Its wide occurrence in experimental systems suggests that it may also influence transcription in many loci, but little is known about its precise nature or underlying mechanisms. Here we report a study of the interaction of two nearly identical transcription units juxtaposed in various arrangements. Each reporter gene in the constructs has its own promoter and enhancer and a strong polyadenylation signal. We used recombinase-mediated cassette exchange
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Marinov, Georgi K., Alexandro E. Trevino, Tingting Xiang, Anshul Kundaje, Arthur R. Grossman, and William J. Greenleaf. "Transcription-dependent domain-scale three-dimensional genome organization in the dinoflagellate Breviolum minutum." Nature Genetics 53, no. 5 (2021): 613–17. http://dx.doi.org/10.1038/s41588-021-00848-5.

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AbstractDinoflagellate chromosomes represent a unique evolutionary experiment, as they exist in a permanently condensed, liquid crystalline state; are not packaged by histones; and contain genes organized into tandem gene arrays, with minimal transcriptional regulation. We analyze the three-dimensional genome of Breviolum minutum, and find large topological domains (dinoflagellate topologically associating domains, which we term ‘dinoTADs’) without chromatin loops, which are demarcated by convergent gene array boundaries. Transcriptional inhibition disrupts dinoTADs, implicating transcription-
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Dang, Yunkun, Liande Li, Wei Guo, Zhihong Xue, and Yi Liu. "Convergent Transcription Induces Dynamic DNA Methylation at disiRNA Loci." PLoS Genetics 9, no. 9 (2013): e1003761. http://dx.doi.org/10.1371/journal.pgen.1003761.

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Lin, William Y., Yunfu Lin, and John H. Wilson. "Convergent transcription through microsatellite repeat tracts induces cell death." Molecular Biology Reports 41, no. 9 (2014): 5627–34. http://dx.doi.org/10.1007/s11033-014-3432-y.

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El Houdaigui, Bilal, Raphaël Forquet, Thomas Hindré, et al. "Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling." Nucleic Acids Research 47, no. 11 (2019): 5648–57. http://dx.doi.org/10.1093/nar/gkz300.

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Abstract DNA supercoiling acts as a global transcriptional regulator in bacteria, that plays an important role in adapting their expression programme to environmental changes, but for which no quantitative or even qualitative regulatory model is available. Here, we focus on spatial supercoiling heterogeneities caused by the transcription process itself, which strongly contribute to this regulation mode. We propose a new mechanistic modeling of the transcription-supercoiling dynamical coupling along a genome, which allows simulating and quantitatively reproducing in vitro and in vivo transcript
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Calero-Nieto, Fernando J., Andrew G. Bert, and Peter N. Cockerill. "Transcription-dependent silencing of inducible convergent transgenes in transgenic mice." Epigenetics & Chromatin 3, no. 1 (2010): 3. http://dx.doi.org/10.1186/1756-8935-3-3.

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Dissertations / Theses on the topic "Convergent transcription"

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Billingsley, Daniel Jeffrey. "Convergent transcription and nested gene models studied by AFM." Thesis, University of Leeds, 2012. http://etheses.whiterose.ac.uk/3149/.

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Genomic DNA is organised in complex spatial arrangements, and a given stretch of DNA may encode more than one gene. In some cases one gene may be entirely contained within a region of the DNA already occupied by another larger gene. The presence of these nested genes, often situated in introns and in the opposite orientation, poses important implications with regards to gene expression, function and regulation. A consequence of the nested gene arrangement is convergent transcription, occurring when two promoters on opposite DNA strands are active. Elucidating the mechanics of multiple interact
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Chammas, Oliver. "Concurrent DNA transcription from convergent and tandem promoters studied by atomic force microscopy." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/15361/.

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With recent advances in sequencing and mapping of genomes, the occurrence of overlapping and nested transcription units is more common than previously thought in both eukaryotes and prokaryotes. The interleaved genome model means that transcriptional interference by collisions between concurrently transcribing RNA polymerases is more likely than ever before. This thesis presents a study of the outcomes of collisions between RNAPs transcribing concurrently from convergent and tandem promoters using AFM to provide a view of single populations seen after collisions. Through the development of an
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Croniger, Colleen Marie. "Convergent transcription of the myosin heavy chain gene (Mhc) and transcriptional unit at chromosomal locus 36B (TU-36B) in Drosophila." Case Western Reserve University School of Graduate Studies / OhioLINK, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=case1059654256.

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Deb, Maharshi Krishna. "Generation of antisense RNAs at convergent gene loci in cells undergoing senescence." Thesis, Toulouse 3, 2016. http://www.theses.fr/2016TOU30274.

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La sénescence, qui est un mécanisme antitumoral majeur, est définie comme un état d'arrêt irréversible de la prolifération cellulaire en réponse à un stress comme l'activation illégitime d'oncogènes. Les cellules qui entrent en sénescence subissent de profonds changements de leur épigénome. Les ARNs antisens sont suspectés de joue des rôles importants dans le contrôle du destin cellulaire et dans des processus cellulaires variés. Dans la levure, le variant d'histone H2A.Z co-opère avec les machineries du RNAi et de l'hétérochromatine pour réprimer sur les loci de gènes convergents l'apparition
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Yi, Jia. "The Role of Convergent Transcription in Regulating Alternative Splicing : Targeted Epigenetic Modification via Repurposed CRISPR/Cas9 System and Its Impact on Alternative Splicing Modulation." Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS382.

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L'épissage alternatif de l'ARN précurseur est un processus co-transcriptionnel qui affecte la grande majorité des gènes humains et contribue à la diversité des protéines. Le dérèglement d'un tel processus est impliqué dans diverses maladies, y compris la tumorigènes. Cependant, les mécanismes qui régulent ces processus restaient à caractériser. Dans cette étude, nous avons montré que les perturbations de l'épissage alternatif étaient corrélées aux dérèglements de la transcription convergente et de la méthylation de l'ADN. Une transcription convergente peut être générée entre des paires de gène
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Omont, Nicolas Képès François. "La convergence des modularités structurelles et fonctionnelles des systèmes complexes." S. l. : Evry-Val d'Essonne, 2009. http://www.biblio.univ-evry.fr/theses/2008/2008EVRY0037.pdf.

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Ivanova, Tsvetomira Georgieva 1978. "The DNA damage and the DNA synthesis checkpoints converge at the MBF transcription factor." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/116932.

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DNA damage is an ongoing threat to both the ability of the cell to faithfully transmit genetic information to its offspring as well as to its own survival. In order to maintain genomic integrity, eukaryotes have developed a highly conserved mechanism to detect, signal and repair damage in DNA, known as the DNA damage response (DDR). In fission yeast the two DDR pathways converge at the regulation of single transcriptional factor complex (MBF) resulting in opposite directions. We have shown that when the DNA-synthesis checkpoint is activated, Max1 is phosphorylated by Cds1 resulting in the abro
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Batlle, Ana. "Regulation of BCL6:p38 MAPK signalling and CTCF transcriptional regulation converge at exon 1." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/6093.

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BCL6 is a zinc finger transcriptional repressor, which is highly expressed in germinal centre B-cells, and is essential for germinal centre formation and T-dependent antibody responses. Deregulated BCL6 expression is associated with certain non- Hodgkin’s lymphomas. High expression is observed in breast cancer. Tight lineage and temporal regulation of BCL6 is, therefore, required for normal immunity and abnormal regulation occurs in cancer. Regulatory mechanisms have been analysed in two settings. Firstly, BCL6 is strongly induced by the tyrosine kinase inhibitor, Imatinib, in chronic myeloid
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Lagouge, Marie. "Identification of cofactor network, including SIRT1 and SRC-3, which converges on energy expenditure through PGC-1α". Université Louis Pasteur (Strasbourg) (1971-2008), 2008. https://publication-theses.unistra.fr/restreint/theses_doctorat/2008/LAGOUGE_Marie_2008.pdf.

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Les organismes s’adaptent aux variations nutritionnelles en modulant l’expression de leurs gènes. Le contrôle transcriptionnel de l’expression génétique implique de nombreux acteurs, dont les corégulateurs. Un dysfonctionnement de ces corégulateurs est connu pour générer un métabolisme cellulaire inadapté et contribuer à la pathogenèse de maladies métaboliques. Nous avons démontré que l’activation pharmacologique in vivo de SIRT1, une désacétylase membre de la famille des sirtuines, protège les souris de l’obésité en augmentant leur dépense énergétique. Au niveau moléculaire, nous avons lié ce
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Demagny, Hadrien. "Convergence des voies de signalisation wnt, fgf et tgf-beta au niveau des facteurs de transcription smad1 et smad4." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066164/document.

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Mon projet de thèse s’inscrit dans le cadre des études visant à comprendre comment les cellules embryonnaires intègrent les différents signaux auxquels elles sont exposées pour s’engager dans une voie de différenciation définie. Il est plus particulièrement centré sur le rôle des protéines Smad dans ces processus et peut se diviser en deux axes de recherche. Le premier a trait au rôle de Mad (Smad1) dans les interactions entre signaux Wnt (Wg) et BMP chez la drosophile. Nous avons pu démontrer que la forme Mad non phosphorylée par le récepteur BMP se lie au complexe transcriptionnel ß-catenin/
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Books on the topic "Convergent transcription"

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Campione, Marina, Amelia Aranega, and Diego Franco. Cardiac looping and laterality. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0014.

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Dextral looping is a complex process which progresses concomitantly with cardiac chamber differentiation and ultimately leads to the final alignment of the cardiac regions. Generation of cardiac asymmetry is crucial to ensure the proper form and consequent function of the heart and thus is a highly regulated process. Molecular signals originate long before morphological asymmetry and therefore can direct it; a complex regulatory network has been characterized which invariably converges on the Tgf-β‎ signalling molecule Nodal and its downstream target, the homeobox transcription factor Pitx2. W
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Miquerol, Lucile. Origin and development of the cardiac conduction system. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0015.

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The cardiac conduction system represents the ‘wiring’ of the heart and orchestrates the propagation of the electrical activity to synchronize heartbeats. It is built from specialized cardiomyocytes expressing a subset of ion channels and gap junctions indispensable for their electrophysiological properties. Although representing only a very small volume of the heart, the conduction system plays a crucial role in the appearance of cardiac arrhythmias. The cells forming the conduction system are derived from the same cardiac progenitors as the working cardiomyocytes, and the choice between these
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Fiddes, Paul S. Charles Williams and C. S. Lewis. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780192845467.001.0001.

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This study of the literary relationship between Charles Williams and C. S. Lewis during the years 1936–1945 focuses on the theme of ‘co-inherence’ at the centre of their friendship. The idea of co-inherence has long been recognized as an important contribution of Williams to theology, and had significant influence on the thought of Lewis. This account of the two writers’ conviction that human persons ‘inhere’ or dwell both in each other and in the triune God reveals many interrelationships between their writings that would otherwise be missed. It also shows up profound differences between thei
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Book chapters on the topic "Convergent transcription"

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Kwak, Sun-Dong, and Moon-Soo Chang. "Development of Transcription Tools That Improved Safety and Convenience." In Convergence and Hybrid Information Technology. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-32692-9_38.

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Thompson, Jacqueline R., and Yingxi Lin. "Nature and Nurture Converge in the Nucleus to Regulate Activity-Dependent Neuronal Development." In Transcriptional Regulation by Neuronal Activity. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-68550-7_10.

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Giglio, Lorenzo. "Ancora su Boccaccio copista di Dante: (almeno) tre ‘redazioni’ della Vita nuova." In Intorno a Boccaccio / Boccaccio e dintorni 2020. Firenze University Press, 2021. http://dx.doi.org/10.36253/978-88-5518-510-3.03.

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The paper studies the editorial practice of Boccaccio in his copies of Dante’s Vita Nuova, through a textual comparison between the two preserved transcriptions and the ones that are only hypothetically referable to his work, thanks to an examination of the varia lectio. What emerged for Vita Nuova from a new comprehensive collatio of the most important witnesses of Boccaccio’s manuscript tradition, put together with what is known about the other Dante’s works copied by Boccaccio himself (lyrics and Commedia), seem to converge in the hypothesis, already suggested by Michele Barbi, that around
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Dwivedi, Nidhi, Vinay Kumar, and Jitendra K. Thakur. "Convergence of Stress-Induced Hormone Signaling Pathways on a Transcriptional Co-Factor." In Mechanism of Plant Hormone Signaling under Stress. John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781118889022.ch28.

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Vineyard Craig M., Verzi Stephen J., Bernard Michael L., and Caudell Thomas P. "A Multimodal Hypertensor Architecture for Association Formation." In Frontiers in Artificial Intelligence and Applications. IOS Press, 2011. https://doi.org/10.3233/978-1-60750-959-2-419.

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Several fields of study have developed sophisticated techniques to process signals of varying types. For example, pattern recognition techniques may seek to convert an audio waveform to a text transcription or to process an image and classify the represented object. However, much of this research focuses upon a single signal type. While such an approach has many useful applications, there are many domains which receive an influx of differing signal types. The brain receives a variety of sensory input signals and although each input stream does receive its share of individual processing, additi
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Seligmann, Herve. "Mutation Patterns Due to Converging Mitochondrial Replication and Transcription Increase Lifespan, and Cause Growth Rate-Longevity Tradeoffs." In DNA Replication-Current Advances. InTech, 2011. http://dx.doi.org/10.5772/24319.

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Ellison, Jay w. "SHOX and Dyschondrosteosis and Turner Syndrome." In Inborn Errors Of Development. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195306910.003.0077.

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Abstract The story of the short stature homeobox (SHOX) gene is an example of how observations of different clinical disorders can eventually converge on a single gene. The disorders in this case are dyschondrosteosis, a skeletal dysplasia; Turner syndrome, an aneuploid condition resulting from a missing sex chromosome; and idiopathic short stature (ISS). SHOX is implicated in each of these conditions, although its contribution to the phenotypes varies with respect to both level of involvement and level of experimental proof. The predicted nature of the gene product (as a DNA-binding transcrip
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Conference papers on the topic "Convergent transcription"

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Sonawane, Dayaram, Manan Pathak, and Venkat R. Subramanian. "Convergence rates for direct transcription of optimal control problems using Second Derivative Methods." In 2016 American Control Conference (ACC). IEEE, 2016. http://dx.doi.org/10.1109/acc.2016.7524918.

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Bang, Jeong-Uk, Sang-Hun Kim, and Oh-Wook Kwon. "Phoneme Set Extension Based on Jensen-Shannon Divergence for Broadcast News Transcription." In 2020 International Conference on Information and Communication Technology Convergence (ICTC). IEEE, 2020. http://dx.doi.org/10.1109/ictc49870.2020.9289468.

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Sophea, Seng, and Somnuk Phon-Amnuaisuk. "Determining a Suitable Desired Factors for Nonnegative Matrix Factorization in Polyphonic Music Transcription." In 2007 International Symposium on Information Technology Convergence (ISITC 2007). IEEE, 2007. http://dx.doi.org/10.1109/isitc.2007.50.

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You, Yeonguk, Hyangrae Noh, Jaeeun Park, Yunsoo Kim, Yongjin KwaK, and Yoonjoong Kim. "A development of a speech data transcription tool for building a spoken corpus." In 2018 International Conference on Information and Communication Technology Convergence (ICTC). IEEE, 2018. http://dx.doi.org/10.1109/ictc.2018.8539450.

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Sunkel, Benjamin D., Dayong Wu, Xiangtao Liu, Zhenqing Ye, Victor Jin, and Qianben Wang. "Abstract 1387: Convergent CREB1/FoxA1 transcriptional activity defines castration-resistant prostate cancer gene expression profile." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-1387.

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Karneswaran, S., and L. T. Biegler. "Convergence rates for direct transcription of optimal control problems with final-time equality constraints using collocation at Radau points." In 2006 American Control Conference. IEEE, 2006. http://dx.doi.org/10.1109/acc.2006.1655348.

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Bodin, Per, Kristian Lindqvist, David Seelbinder, et al. "Attitude Guidance Using On-Board Optimisation." In ESA 12th International Conference on Guidance Navigation and Control and 9th International Conference on Astrodynamics Tools and Techniques. ESA, 2023. http://dx.doi.org/10.5270/esa-gnc-icatt-2023-113.

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The on-board ability to autonomously plan and execute constrained attitude manoeuvres is expected to play an important role in many future space missions. The work presented in this paper summarizes the results from a recently completed ESA study in which such functionality was examined. The study included the application of on-board embedded optimisation techniques to solve constrained attitude guidance problems. Different heritage methods not based on on-board optimisation were also developed and applied for comparison. The study demonstrated the capabilities in a number of test cases associ
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Cuiffo, Benjamin, Antoine Campagne, George W. Bell, et al. "Abstract 173: Tumor proximal mesenchymal stem cells initiate a pro-metastatic microRNA regulatory network which acts via convergent targeting of the speech-associated transcriptional repressor FOXP2." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-173.

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Garg, Rachana, Jorge Blando, Carlos Perez, Martin Abba, Fernando Benavides та Marcelo Kazanietz. "Abstract LB-230: Oncogenic PKC epsilon and Pten loss converge on activating CXCL13 via atypical NF-κB transcriptional signaling in prostate cancer progression". У Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-lb-230.

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Linher-Melville, K., MG Nashed, R. Ungard, S. Haftchenary, PT Gunning, and G. Singh. "Abstract P3-03-13: Chronic inhibition of signal transducer and activator of transcription 3/5 in treatment-resistant human breast cancer cell subtypes: Convergence on the reactive oxyten species/SUMOylation pathway and its effects on xCT expression and system xc-activity." In Abstracts: 2016 San Antonio Breast Cancer Symposium; December 6-10, 2016; San Antonio, Texas. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.sabcs16-p3-03-13.

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Reports on the topic "Convergent transcription"

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Levy, Avraham A., and Virginia Walbot. Regulation of Transposable Element Activities during Plant Development. United States Department of Agriculture, 1992. http://dx.doi.org/10.32747/1992.7568091.bard.

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We have studied the regulation of the maize Ac and MuDR transposable elements activities during plant development. Ac was studied in an heterologous system (transgenic tobacco plants and cell suspensions) while MuDR was studied in the native maize background. The focus of this study was on the transcriptional regulation of Ac and MuDR. For Ac, the major achievements were to show that 1-It is autoregulated in a way that the Ac-encoded transposase can repress the activity of its own promoter; 2-It is expressed at low basal level in all the plant organs that were studied, and its activity is stro
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Samach, Alon, Douglas Cook, and Jaime Kigel. Molecular mechanisms of plant reproductive adaptation to aridity gradients. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7696513.bard.

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Annual plants have developed a range of different mechanisms to avoid flowering (exposure of reproductive organs to the environment) under adverse environmental conditions. Seasonal environmental events such as gradual changes in day length and temperature affect the timing of transition to flowering in many annual and perennial plants. Research in Arabidopsis and additional species suggest that some environmental signals converge on transcriptional regulation of common floral integrators such as FLOWERING LOCUS T (FT). Here we studied environmental induction of flowering in the model legume M
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