Relevant bibliographies by topics / Curcumin Phytosomes

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Academic literature on the topic 'Curcumin Phytosomes'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Curcumin Phytosomes"

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Pawar, Harshal A., and Bhagyashree D. Bhangale. "Development and Evaluation of Sustained Release Lipid Nanocarriers for Curcumin." Current Nanomaterials 5, no. 3 (2020): 224–35. http://dx.doi.org/10.2174/2405461505999200917122147.

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Background: Lipid based excipients have increased acceptance nowadays in the development of novel drug delivery systems in order to improve their pharmacokinetic profiles. Drugs encapsulated in lipids have enhanced stability due to the protection they experience in the lipid core of these nano-formulations. Phytosomes are newly discovered drug delivery systems and novel botanical formulation to produce lipophilic molecular complex which imparts stability, increases absorption and bioavailability of phytoconstituent. Curcumin, obtained from turmeric (Curcuma longa), has a wide range of biologic
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Nikhil, Khopade* Kakasaheb kore Sucheta bhise Adinath bhusari Dr. Rajkumar Shete. "Curcumin Phytosomes: A Promising Nanocarrier System for Enhancing Bioavailability and Therapeutic Efficacy." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2448–60. https://doi.org/10.5281/zenodo.15425503.

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Curcumin: a polyphenolic compound extracted from turmeric with widespread therapeutic potential, particularly its anti-inflammatory, antioxidant, anticancer, and antimicrobial properties. But its clinical usage is limited by low aqueous solubility, low absorption, rapid metabolism, and fast systemic clearance, leading to poor bioavailability. To overcome these limitations, nanocarrier systems such as phytosomes a special phospholipid complex system have been introduced for effective drug delivery. Curcumin phytosomes are a styudied formulation consisting of a mixture of curcumin
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Mavi, Nitin, Pankaj Kumar Sharma, and Dilip Kumar Gupta. "Phytosomes: Bridging Nature And Nanotechnology For Enhanced Drug Delivery." International Journal of Environmental Sciences 11, no. 8s (2025): 801–18. https://doi.org/10.64252/qj5e5a23.

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The development of phytosomal drug delivery systems represents a significant advancement in natural medicine, addressing longstanding challenges associated with botanical compounds, including poor absorption and permeation rates, as well as limited bioavailability. The molecular interaction between phytoconstituents and phospholipids, particularly phosphatidylcholine, results in the formation of phytosomes, which substantially improve the lipophilicity and absorption characteristics of hydrophilic extracts. This phytosomal system provides two primary advantages through its pharmaco-absorptive
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Allam, Ahmed N., Ibrahim A. Komeil, and Ossama Y. Abdallah. "Curcumin phytosomal softgel formulation: Development, optimization and physicochemical characterization." Acta Pharmaceutica 65, no. 3 (2015): 285–97. http://dx.doi.org/10.1515/acph-2015-0029.

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Abstract Curcumin, a naturally occurring lipophilic molecule can exert multiple and diverse bioactivities. However, its limited aqueous solubility and extensive presystemic metabolism restrict its bioavailability. Curcumin phytosomes were prepared by a simple solvent evaporation method where free flowing powder was obtained in addition to a newly developed semisolid formulation to increase curcumin content in softgels. Phytosomal powder was characterized in terms of drug content and zeta potential. Thirteen different softgel formulations were developed using oils such as Miglyol 812, castor oi
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Kumar, M. Surendra, K. Dhivya, D. Lokesh, et al. "Phytosomes: nature’s secret to enhanced bioavailability." Journal of Applied Pharmaceutical Research 12, no. 6 (2024): 88–99. https://doi.org/10.69857/joapr.v12i6.702.

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Background: Medicinal herbs have long been used for treating various ailments, with plant-derived compounds recognized for their therapeutic benefits and minimal side effects compared to conventional medicines. However, issues with the bioavailability of active herbal components have limited their effectiveness. Phytosomes, or herbosomes, are a drug delivery technology that enhances the absorption and bioavailability of these plant-based compounds, providing a potential solution for maximizing the medicinal efficacy of herbal ingredients. Method: Phytosome complexes are synthesized by combinin
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Pratiksha, Hajare Mahesh Reddy Vedashree Dhumekar Yogesh Somwanshi. "Enhancing Cancer Therapy with Phytosomes: A Review of Mechanisms." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 1889–99. https://doi.org/10.5281/zenodo.14450759.

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Phytosomes, advanced delivery systems that enhance the bioavailability and efficacy of plant-derived compounds, have gained significant attention in cancer therapy. This review explores the mechanisms through which phytosomes enhance anticancer activity, including improved drug solubility, enhanced cellular uptake, and sustained drug release. We discuss their ability to overcome challenges in conventional therapies, such as poor bioavailability, systemic toxicity, and drug resistance, by encapsulating bioactive phytochemicals like curcumin, quercetin, and resveratrol. Moreover, we examine thei
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Saeed, Muhammad, Soheil Sadr, Arian Gharib, et al. "Phytosomes: A Promising Nanocarrier for Enhanced Delivery of Herbal Compounds in Cancer Therapy." Journal of Lab Animal Research 1, no. 1 (2022): 26–32. http://dx.doi.org/10.58803/jlar.v1i1.8.

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Cancer is a life-threatening disease that remains a global health problem, with millions of people diagnosed yearly. Despite significant progress in cancer treatment, conventional chemotherapy still faces several limitations, including poor solubility, low bioavailability, lack of selectivity, and severe side effects. Therefore, alternative therapeutic strategies are necessary to improve cancer therapy. This review aimed to provide an updated overview of phytosome complexes and their potential application in cancer therapy, including their formulation techniques, transportation mechanism throu
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Sneha, Karkute Kunti Shinde Pooja Rasal*. "Application Of Phytosome In Wound Healing: A Comprehensive Review." International Journal of Pharmaceutical Sciences 2, no. 11 (2024): 600–611. https://doi.org/10.5281/zenodo.14151452.

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Wound healing is a crucial physiological process involving complex cellular and molecular mechanisms. Conventional treatments often struggle with limited drug bioavailability, stability, and side effects. Phytosome technology offers an innovative solution to enhance the efficacy of phytoconstituents in wound healing. This review explores the application of phytosomes in wound care, focusing on their mechanisms of action, specific phytoconstituents used, clinical evidence, and future directions. Phytosome-based formulations, such as those containing curcumin, quercetin, and resveratrol, have de
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Ibrahim, Angum MM, Siham K. AbdelRahim, Huriyyah A. Alturaifi, and Intisar AM Elalawy. "Development and Evaluation of Herbal Antiacne Gel Formulation Using Curcumin Phytosomes ." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1435–40. http://dx.doi.org/10.25258/ijddt.14.3.26.

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Acne vulgaris is a persistent inflammatory condition affecting the pilosebaceous unit that manifests as various skin lesions, including papules, comedones, cysts, pustules, and abscesses. Curcumin, extracted from Curcuma longa rhizomes (Family: Zingiberaceae), is identified for its potent antioxidant, wound-healing, and anti-inflammatory properties. This study aimed to develop an herbal antiacne gel formulation incorporating bioactive curcumin in phytosomes. The formulated gel was evaluated for several physicochemical properties, including pH, spreadability, viscosity, drug content, etc. Addit
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Shrayner, E. V., K. M. Nikolaychuk, M. V. Khvostov, et al. "Pharmacokinetics, side effects, dosage forms, drug interactions of curcu-mine." Experimental and Clinical Gastroenterology, no. 9 (March 6, 2025): 147–60. https://doi.org/10.31146/1682-8658-ecg-229-9-147-160.

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This review presents current data on the pharmacokinetics, side effects, dosage forms and interactions of curcumin. Curcumin, the major bioactive component of turmeric, has low bioavailability due to its low water solubility, rapid metabolism in the liver and rapid excretion from the body. The main pathways of curcumin metabolism are described, including its reduction and subsequent conjugation with glucuronic acid and sulphates. Side effects of curcumin such as hyperoxaluria, iron deficiency anaemia, hepatotoxicity, arrhythmias, allergic reactions and potential carcinogenic properties are dis
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Book chapters on the topic "Curcumin Phytosomes"

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Hatamipour, Mahdi, Tannaz Jamialahmadi, Mahin Ramezani, et al. "Protective Effects of Curcumin Phytosomes Against High-Fat Diet-Induced Atherosclerosis." In Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-64872-5_4.

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Mirhafez, Seyed Reza, Mohsen Azimi-Nezhad, Maryam Dehabeh, et al. "The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial." In Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-64872-5_3.

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Gerapati, Kiran. "Innovative Drug Delivery Systems For Herbal Hepatoprotective Agents: Advances And Future Directions." In Advancements in Hepatoprotective Herbal Medicines Current Trends, Significance and Future Perspectives. Genome Publications, 2025. https://doi.org/10.61096/978-81-981372-8-9_16.

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The growing prevalence of liver diseases has intensified the search for more effective hepatoprotective therapies. While herbal medicines have demonstrated hepatoprotective properties, their therapeutic potential is often limited by poor bioavailability, rapid metabolism, and low aqueous solubility. Recent advancements in innovative drug delivery systems offer promising solutions to enhance the efficacy of herbal hepatoprotective agents. This chapter explores cutting-edge approaches, including liposomes, phytosomes, polymeric nanoparticles, nanoemulsions, solid lipid nanoparticles, and hydroge
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Rajendran, Vanitha Devi. "Emerging Trends In Hepatoprotective Herbal Solutions For Liver Health." In Advancements in Hepatoprotective Herbal Medicines Current Trends, Significance and Future Perspectives. Genome Publications, 2025. https://doi.org/10.61096/978-81-981372-8-9_14.

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The increasing prevalence of liver diseases has spurred growing interest in hepatoprotective herbal solutions as alternatives or complementary therapies to conventional treatments. The liver, essential for detoxification, metabolism, and immune regulation, is vulnerable to damage from infections, toxins, metabolic disorders, and lifestyle-related factors. Emerging trends in herbal medicine highlight the potential of plant-based compounds to mitigate liver damage, enhance detoxification, and promote hepatic regeneration. This chapter explores the latest advancements in hepatoprotective herbs, i
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Puttegowda, Venkatesh Dinnekere. "Herbal Protectants For Liver Function During Health Challenges." In Advancements in Hepatoprotective Herbal Medicines Current Trends, Significance and Future Perspectives. Genome Publications, 2025. https://doi.org/10.61096/978-81-981372-8-9_13.

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The liver plays a critical role in detoxification, metabolism, and immune regulation, making it highly susceptible to damage from infections, toxins, autoimmune disorders, metabolic stress, and substance overuse. While conventional medical treatments focus on disease management, herbal protectants have long been utilized in traditional medicine systems to support liver function and resilience. This chapter explores the role of herbal interventions in safeguarding hepatic health during various challenges, including viral and bacterial infections, metabolic disorders like non-alcoholic fatty liv
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Conference papers on the topic "Curcumin Phytosomes"

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Al-Yasari, Ali Mosa Rashid, Mohammed A. Aboktifa, Zainab Abdulkaleq Ahmed, Hadeel S. Almaliki, Ruqaya K. Abbas, and Adnan Mansour Jasim. "The physiological role of phytosomal curcumin to mitigate hemolytic anemia and cytogenic effect induced by phenylhydrazine in rats." In TRANSPORT, ECOLOGY, SUSTAINABLE DEVELOPMENT: EKO VARNA 2023. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0191865.

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