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Journal articles on the topic 'Cytotoxic styryl lactones'

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1

Wiart, Christophe. "GoniothalamusSpecies: A Source of Drugs for the Treatment of Cancers and Bacterial Infections?" Evidence-Based Complementary and Alternative Medicine 4, no. 3 (2007): 299–311. http://dx.doi.org/10.1093/ecam/nem009.

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Irrespective of the presence of cytotoxic acetogenins and styryl-lactones in the genusGoniothalamus, only 22 species in the genusGoniothalamus, out of 160 species (13.7%) have so far been investigated. In an effort to promote further research on the genusGoniothalamuswhich could represent a source of drugs for the treatment of cancers and bacterial infections, this work offers a broad analysis of current knowledge onGoniothalamusspecies. Therefore, it includes (i) taxonomy (ii) botanical description (iii) traditional medicinal uses and (iv) phytochemical and pharmacological studies. We discuss
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2

Babu Mereyala, Hari, and Maju Joe. "Cytotoxic Activity of Styryl Lactones and their Derivatives." Current Medicinal Chemistry-Anti-Cancer Agents 1, no. 3 (2001): 293–300. http://dx.doi.org/10.2174/1568011013354606.

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3

Rasol, Nurulfazlina Edayah, Fasihuddin Badruddin Ahmad, Chun-Wai Mai, et al. "Styryl Lactones from Roots and Barks Goniothalamus lanceolatus." Natural Product Communications 13, no. 12 (2018): 1934578X1801301. http://dx.doi.org/10.1177/1934578x1801301203.

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A new styryl lactone, 5 R,6 R-5-hydroxy-6-styryltetrahydropyrane-2-one 2 was isolated from the roots of an endemic Goniothalamus lanceolatus Miq. of Sarawak, Malaysia. Furthermore, seven previously undescribed diastereomers, 5 R,6 R-5-hydroxygoniothalamin 3, 5 R,6 R-5-acetylgoniothalamin 4, 6 S,7 S,8 S-goniodiol-7-monoacetate 5, 6 S,7 S,8 S-goniodiol-8-monoacetate 6, goniofupyrone B 7, deoxygoniopypyrone B 8 and 1 S,5 S,7 R,8 S,3- endo,7- endo-(+)-8- epi-9-deoxygoniopypyrone acetate 9, along with six known styryl lactones (1, 10–15) were also isolated and characterized. 6 S-goniothalamin 1 is
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4

Tuchinda, Patoomratana, Bamroong Munyoo, Manat Pohmakotr, et al. "Cytotoxic Styryl-Lactones from the Leaves and Twigs ofPolyalthia crassa." Journal of Natural Products 69, no. 12 (2006): 1728–33. http://dx.doi.org/10.1021/np060323u.

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5

Shahzad Aslam, Muhammad, Muhammad Syarhabil Ahmad, Awang Soh Mamat, Muhammad Zamharir Ahmad, and Faridah Salam. "Goniothalamus: Phytochemical and Ethnobotanical Review." Recent Advances in Biology and Medicine 02 (2016): 34. http://dx.doi.org/10.18639/rabm.2016.02.292264.

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Goniothalamusspecies are used in widespread medicines for abortion, anti-aging, body pains, rheumatism, skin complaints, typhoid fever, tympanites, stomach ache and fever. The present study reviews the distribution of species along with their synonyms, their traditional usage, and correlated chemical compounds ofGoniothalamusspecies with stress on the authentication of their ethnobotanical uses. The findings in someGoniothalamusspecies suggest that the chemical nature of their derivatives, such as acetogenins and styryl-lactones, may justify the use of these species against cancer in Asian tra
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6

Popsavin, Velimir, Goran Benedeković, Bojana Srećo, et al. "Divergent Synthesis of Cytotoxic Styryl Lactones fromd-Xylose. The First Total Synthesis of (+)-Crassalactone C." Organic Letters 9, no. 21 (2007): 4235–38. http://dx.doi.org/10.1021/ol701734s.

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7

Popsavin, Velimir, Ivana Kovačević, Goran Benedeković, Mirjana Popsavin, Vesna Kojić, and Gordana Bogdanović. "Divergent Synthesis of Cytotoxic Styryl Lactones Related to Goniobutenolides A and B, and to Crassalactone D." Organic Letters 14, no. 23 (2012): 5956–59. http://dx.doi.org/10.1021/ol302860z.

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8

Popsavin, Velimir, Goran Benedeković, Bojana Srećo, et al. "Enantiodivergent synthesis of cytotoxic styryl lactones from d-xylose. The first total synthesis of (+)- and (−)-crassalactone C." Tetrahedron 65, no. 51 (2009): 10596–607. http://dx.doi.org/10.1016/j.tet.2009.10.079.

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9

Popsavin, Velimir, Goran Benedeković, Mirjana Popsavin, Vesna Kojić, and Gordana Bogdanović. "Divergent synthesis of cytotoxic styryl lactones isolated from Polyalthia crassa. The first total synthesis of crassalactone B." Tetrahedron Letters 51, no. 26 (2010): 3426–29. http://dx.doi.org/10.1016/j.tetlet.2010.04.114.

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10

Tantithanaporn, S., C. Wattanapiromsakul, A. Itharat, and N. Keawpradub. "Cytotoxic activity of acetogenins and styryl lactones isolated from Goniothalamus undulatus Ridl. root extracts against a lung cancer cell line (COR-L23)." Phytomedicine 18, no. 6 (2011): 486–90. http://dx.doi.org/10.1016/j.phymed.2010.10.010.

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11

Raghavendar Reddy, Parigi, and Biswanath Das. "Stereoselective Total Synthesis of Crassalactone A, a Natural Cytotoxic Styryl Lactone." Helvetica Chimica Acta 98, no. 4 (2015): 509–14. http://dx.doi.org/10.1002/hlca.201400237.

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12

Wach, Jean-Yves, Stephan Güttinger, Ulrike Kutay, and Karl Gademann. "The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transport." Bioorganic & Medicinal Chemistry Letters 20, no. 9 (2010): 2843–46. http://dx.doi.org/10.1016/j.bmcl.2010.03.049.

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13

Lоncаr, Dаvоr, Nаtаsа Мilоsеvic, Jasmina Vitas, Milica Karadzic, Lidija Jevric, and Goran Benedekovic. "Chromatographic lipophilicity and pharmacokinetic behavior of some newly synthesized styryl lactone stereoisomers." Acta Periodica Technologica, no. 48 (2017): 197–209. http://dx.doi.org/10.2298/apt1748197l.

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The RP-HPLC retention constants of several newly synthesized cytotoxic styryl lactone stereoisomers were determined as parameters of their lipophilicity. Stereochemistry of the compounds has an effect on the retention behavior of only tricyclic isomers. For them, the difference in retention and chromatographic lipophilic parameters are significant. The chromatographic lipophilic parameters of all compounds were correlated with a fourteen computer calculated lipophilic parameters, log P, and pharmacokinetic parameters. Significant linear correlations (R2 adj>0.90) were obtained between MLog
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14

Reddy, Parigi Raghavendar, and Biswanath Das. "ChemInform Abstract: Synthetic Studies on Natural Products. Part 83. Stereoselective Total Synthesis of Crassalactone A, a Natural Cytotoxic Styryl Lactone." ChemInform 46, no. 36 (2015): no. http://dx.doi.org/10.1002/chin.201536247.

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15

Tsubuki, Masayoshi, Kazuo Kanai, Hiromasa Nagase, and Toshio Honda. "ChemInform Abstract: Stereocontrolled Syntheses of Novel Styryl Lactones, (+)-Goniodiol, (+)-Goniotriol, (+)-8-Acetylgoniotriol, (+)-Goniofufurone, (+)-9-Deoxygoniopypyrone, (+)-Goniopypyrone, and (+)-Altholactone from Common Intermediates and Cytotoxicit." ChemInform 30, no. 30 (2010): no. http://dx.doi.org/10.1002/chin.199930247.

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16

Popsavin, Velimir, Goran Benedekovic, Bojana Sreco, et al. "ChemInform Abstract: Divergent Synthesis of Cytotoxic Styryl Lactones from D-Xylose. The First Total Synthesis of (+)-Crassalactone C." ChemInform 39, no. 10 (2008). http://dx.doi.org/10.1002/chin.200810223.

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17

Popsavin, Velimir, Goran Benedekovic, Mirjana Popsavin, Vesna Kojic, and Gordana Bogdanovic. "ChemInform Abstract: Divergent Synthesis of Cytotoxic Styryl Lactones Isolated from Polyalthia crassa. The First Total Synthesis of Crassalactone B." ChemInform 41, no. 42 (2010). http://dx.doi.org/10.1002/chin.201042194.

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