Academic literature on the topic 'D cognitive impairment'

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Journal articles on the topic "D cognitive impairment"

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R., Rajalakshmi, Chinnappa A. Uthaiah, Ramya C. M., et al. "Comparative assessment of cognitive impairment and oxidative stress markers among vitamin D insufficient elderly patients with and without type 2 diabetes mellitus (T2DM)." PLOS ONE 17, no. 6 (2022): e0269394. http://dx.doi.org/10.1371/journal.pone.0269394.

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Background Disorders of mental health are known to affect cognitive functions, hence called as cognitive disorders. Impaired glucose metabolism, insulin resistance, vitamin-D deficiency and oxidative stress are some of the key early events reported to be involved in the pathogenesis of most common cognitive disorders, which include Alzheimer’s disease. Type-2 diabetes mellitus (T2DM) is one of the known contributing factors of cognitive impairment and dementia. Methods A cross sectional study was carried out in 145 subjects, who were assessed for cognitive function by modified mini mental stat
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Imerbsin, Nalinee, Prapimporn Chattranukulchai Shantavasinkul, Pirada Witoonpanich, et al. "Vitamin D and Cognitive Impairment." Nutrients 17, no. 8 (2025): 1301. https://doi.org/10.3390/nu17081301.

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Background: Vitamin D deficiency is recognized as a significant public health concern, and it has been identified as one of the potentially modifiable risk factors for mild cognitive impairment (MCI). However, evidence regarding the relationship between vitamin D status and cognitive function remains conflicting. Objective: Therefore, this study aimed to examine the prevalence of vitamin D deficiency in the Thai elderly population and an association between vitamin D status and cognitive function, adiposity, and insulin sensitivity. Methods: This study enrolled participants aged 55–80 years wi
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Pinzon, Rizaldy, Vincent Ongko Wijaya, and Dessy Paramitha. "Vitamin D Status and Cognitive Performance of Post Stroke Patients." Molecular and Cellular Biomedical Sciences 5, no. 1 (2021): 22. http://dx.doi.org/10.21705/mcbs.v5i1.170.

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Background: The prevalence of post-stroke cognitive impairment (PSCI) ranges from 20-80%. Some studies found that vitamin D deficiency was common in stroke patients, yet the relationship with cognitive performance remains unclear. The study aimed to investigate the relationship between levels of vitamin D and cognitive performance in post-stroke patients.Materials and Methods: This was a cross-sectional study with 20 post-ischemic stroke patients. Vitamin D levels were measured using enzyme-linked fluorescent assay (ELFA). The cognitive performance was assessed by computerized mini-mental stat
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Farr, Susan A., Kelvin A. Yamada, D. Allan Butterfield, et al. "Obesity and Hypertriglyceridemia Produce Cognitive Impairment." Endocrinology 149, no. 5 (2008): 2628–36. http://dx.doi.org/10.1210/en.2007-1722.

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Obesity is associated with cognitive impairments. Long-term mechanisms for this association include consequences of hyperglycemia, dyslipidemia, or other factors comprising metabolic syndrome X. We found that hypertriglyceridemia, the main dyslipidemia of metabolic syndrome X, is in part responsible for the leptin resistance seen in obesity. Here we determined whether triglycerides have an immediate and direct effect on cognition. Obese mice showed impaired acquisition in three different cognitive paradigms: the active avoidance T-maze, the Morris water maze, and a food reward lever press. The
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Taslim Pinzon, Rizaldy, Nindya Stephanie Christina, Oey Yedida Stephanie Sugianto, and Tillandsia Filli Folia Primastuti. "Correlation between vitamin D levels and cognitive impairment on 90 days post ischemic stroke patients." Romanian Journal of Neurology 21, no. 3 (2022): 237–41. http://dx.doi.org/10.37897/rjn.2022.3.7.

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The prevalence of ischemic stroke based on the American Heart Association (AHA) data in 2019 reached 77.2 million people. As much as 72% of post ischemic stroke patients got cognitive impairment. Vitamin D deficiency is often found in post-stroke patients and causes functional decline. This study aims to assess the relationship between vitamin D levels and cognitive impairment in 90 days post ischemic stroke patients. This study is a cross-sectional study using secondary data from medical records at Bethesda Hospital Yogyakarta taken from January to March 2021. Cognitive impairment in 90 days
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Dye, A., J. Gehling, and J. Buchanan. "C-01 An Evaluative Study of a Cognitive Training Program on Cognitive Outcomes in Older Adults with Moderate to Severe Cognitive Impairment." Archives of Clinical Neuropsychology 34, no. 6 (2019): 1028. http://dx.doi.org/10.1093/arclin/acz034.163.

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Abstract Objective Because medical interventions for persons with dementia have limited effectiveness, there is a need to evaluate non-pharmacological interventions designed to support individuals with cognitive impairment. Cognitive training is a non-pharmacological approach aimed at improving or maintaining cognitive functioning through practice. The current study evaluated the effects of a cognitive training program in older adults with moderate to severe cognitive impairment. Method Data were collected from seven females and one male with a mean age of 83.1 who met criteria for moderate to
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de la Fuente, Javier, Jacob Hjelmborg, Mette Wod, et al. "Longitudinal Associations of Sensory and Cognitive Functioning: A Structural Equation Modeling Approach." Journals of Gerontology: Series B 74, no. 8 (2018): 1308–16. http://dx.doi.org/10.1093/geronb/gby147.

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Abstract Objectives Although visual and hearing impairments have been found to be associated with cognitive decline in the old age, the mechanism underlying this relationship remains unclear. This study aimed at assessing the predictive role of visual and hearing difficulties on subsequent cognitive functioning. Method From the cohort of the first (2002) and fifth waves (2010) of the English Longitudinal Study of Ageing (ELSA), 3,508 individuals aged 60 and older were included in the study. Five self-reported visual and hearing functioning items were used to assess sensory functioning at basel
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Bora, E., B. Binnur Akdede, and K. Alptekin. "Neurocognitive impairment in deficit and non-deficit schizophrenia: a meta-analysis." Psychological Medicine 47, no. 14 (2017): 2401–13. http://dx.doi.org/10.1017/s0033291717000952.

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BackgroundMost studies suggested that patients with deficit schizophrenia have more severe impairment compared with patients with non-deficit schizophrenia. However, it is not clear whether deficit and non-deficit schizophrenia are associated with differential neurocognitive profiles.MethodsThe aim of this meta-analytic review was to compare cognitive performances of deficit and non-deficit patients with each other and with healthy controls. In the current meta-analysis, differences in cognitive abilities between 897 deficit and 1636 non-deficit patients with schizophrenia were examined. Cogni
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Kamyshna, Iryna I., Larysa B. Pavlovych, and Aleksandr M. Kamyshnyi. "Prediction of the cognitive impairment development in patients with autoimmune thyroiditis and hypothyroidism." Endocrine Regulations 56, no. 3 (2022): 178–89. http://dx.doi.org/10.2478/enr-2022-0019.

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Abstract Objective. The aim of the present work is to define the risk factors that can affect the presence of a cognitive impairment and analyze the associations of the brain-derived neurotrophic factor (BDNF) gene polymorphism (rs6265), vitamin D receptor (VDR) gene polymorphism (rs2228570), and N-methyl-D-aspartate (NMDA) receptor gene polymorphism (rs4880213) with the cognitive impairment in patients with autoimmune thyroiditis and hypothyroidism in the Western Ukraine population and predict the development of cognitive disorders in these patients. Methods. The study involved 153 patients w
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Cruz, Daniela, Hélder Balouta, and Rafaela Ventura. "Papel da vitamina D no tratamento do défice cognitivo ligeiro – qual a evidência?" RIAGE - Revista Ibero-Americana de Gerontologia 3 (June 30, 2023): 92–101. http://dx.doi.org/10.61415/riage.45.

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O Défice Cognitivo Ligeiro (DCL) define-se como um decréscimo da função cognitiva, reconhecido pelo próprio e por familiares, que vai mais além das alterações que decorrem da idade. O DCL pode progredir para demência, sendo relevante a prevenção, diagnóstico e tratamento. Vários suplementos foram associados a uma melhoria da função cognitiva, nomeadamente a vitamina D. Este estudo deteve como objetivo rever a evidência do uso de vitamina D no tratamento do DCL. Foi utilizada uma metodologia RBE com critérios de inclusão segundo a metodologia PICO: População – idosos com DCL; Intervenção – supl
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Dissertations / Theses on the topic "D cognitive impairment"

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Sambuchi, Nathalie. "Analyse des troubles de la métamémoire de la phase pré-symptomatique de la maladie d'Alzheimer." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4772.

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La difficulté de la plainte mnésique est son aspect subjectif et son évaluation. Le concept de Subjective Cognitive Impairment (SCI) est une réalité épidémiologique. Nous rapportons ici notre expérience, au sein du service de neurologie Comportementale des Hôpitaux sud de MARSEILLE d'une cohorte de sujets consultants sur une période de plus de 6 ans, sur le plan neurologique, neuropsychologique et de la neuroimagerie. Le SCI représente un état anatomo-clinique défini, qu'on peut séparer à la fois des Contrôles Normaux (CN) et des Mild Cognitive Impairment-Amnésiques (MCI-A), sur le plan neurop
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Gebel, Sophie [Verfasser], and Robert [Akademischer Betreuer] Weissert. "Cognitive impairment bei Patienten mit multipler Sklerose und die cognitive reserve Theorie / Sophie Gebel. Betreuer: Robert Weissert." Regensburg : Universitätsbibliothek Regensburg, 2016. http://d-nb.info/1096751720/34.

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Graunke, Anders [Verfasser]. "Stoffwechsel und Inflammation bei Patienten mit Mild Cognitive Impairment (MCI) / Anders Graunke." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2014. http://d-nb.info/1052529968/34.

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Kikkert, Lisette. "Gait characteristics as indicators of cognitive impairment in geriatric patients." Thesis, Université Grenoble Alpes (ComUE), 2018. http://www.theses.fr/2018GREAS013/document.

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Le dé cit cognitif est une cause majeure de handicap de la personne âgée. Du fait de l’augmentation de la durée de vie, le nombre de personnes âgées qui pourraient béné cier d’une prise en charge spécialisée dans le but de ralentir leur perte fonctionnelle va croitre. En dépit de traitement validé qui stoppe le processus neurodégénératif, des interventions spéci ques peuvent en ralentir les manifestations. De nombreuses études expérimentales, neuroscienti ques et comportementales ont démontré la relation étroite entre cognition en motricité.Ce travail doctoral propose d’explorer si certaines c
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Grossin, Bruno Vercelletto Martine. "La plainte mnésique du sujet âgé à propos du concept de " Mild Cognitive Impairment /." [S.l.] : [s.n.], 2004. http://theses.univ-nantes.fr/thesemed/MEDgrossin.pdf.

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Berens, Miriam [Verfasser]. "Neurofilament Light Chain als Prädiktor kognitiven Abbaus bei Mild Cognitive Impairment / Miriam Berens." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2021. http://d-nb.info/1235756904/34.

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Ritter, Emilie. "Topographical recognition memory and autobiographical memory in amnestic mild cognitive impairment : a longitudinal study." Université Louis Pasteur (Strasbourg) (1971-2008), 2007. https://publication-theses.unistra.fr/public/theses_doctorat/2007/RITTER_Emilie_2007.pdf.

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Le syndrome de amnestic mild cognitive impairment (aMCI) présente un risque élevé d’évoluer en démence de type Alzheimer (DAT), mais pourrait avoir d’autres causes, telles que la dépression. L’objectif de cette thèse était de rechercher des marqueurs de la DAT préclinique. Nous avons observé l’évolution cognitive de patients aMCI pendant deux ans afin de discriminer les déclinants des stables cognitivement. En se basant sur les substrats neuronaux, nous avons supposé que des déficits de la mémoire de reconnaissance topographique (MRT) et de la mémoire autobiographique (Mab) pourraient être des
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Ritter, Emilie Manning Lilianne Monsch Andreas. "Topographical recognition memory and autobiographical memory in amnestic mild cognitive impairment a longitudinal study /." Strasbourg : Université Louis Pasteur, 2007. http://eprints-scd-ulp.u-strasbg.fr:8080/791/01/RITTER2007.pdf.

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Thèse de doctorat : Neuropsychologie : Strasbourg 1 : 2007. Thèse de doctorat : Neuropsychologie : Bâle - Suisse : 2007.<br>Thèse soutenue en co-tutelle. Titre provenant de l'écran-titre. Bibliogr. f. 83-106.
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Wu-Puigbo, Ya-Huei. "Validation d'un test de barrage informatisé sur tablette évaluant les fonctions exécutives auprès d'une population gériatrique." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCB210/document.

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Dans le contexte du diagnostic précoce de la maladie d’Alzheimer, une direction de la recherche émerge autour de l’informatisation de tests cognitifs. Nous avons conçu un test de barrage informatisé sur tablette (test e-CT), développé à partir d’un test de barrage papier-crayon. Nous avons étudié les variables influençant les performances au test e-CT et ses propriétés psychométriques. Nous avons observé que chez les sujets âgés sains, la seule variable influençant était l’âge. Les performances au test e-CT n’étaient pas influencées par l’expérience avec un appareil informatique. Cependant, ch
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Karrasch, Mira. "Normal aging, mild cognitive impairment and Alzheimer's disease : neuropsychological screening and electrophysiological correlates of working memory /." Åbo : Åbo akademi university, 2005. http://catalogue.bnf.fr/ark:/12148/cb40223492j.

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Books on the topic "D cognitive impairment"

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Voinescu, Alexandra, Nadia Wasi Iqbal, and Kevin J. Martin. Management of chronic kidney disease-mineral and bone disorder. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0118_update_001.

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In all patients with chronic kidney disease (CKD) stages 3–5, regular monitoring of serum markers of CKD-mineral and bone disorder, including calcium (Ca), phosphorus (P), parathyroid hormone (PTH), 25-hydroxyvitamin D, and alkaline phosphatase, is recommended. Target ranges for these markers are endorsed by guidelines. The principles of therapy for secondary hyperparathyroidism include control of hyperphosphataemia, correction of hypocalcaemia, use of vitamin D sterols, use of calcimimetics, and parathyroidectomy. of hyperphosphataemia is crucial and may be achieved by means of dietary P rest
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Book chapters on the topic "D cognitive impairment"

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Araújo, Marcelo R. Moura, Katia M. Poloni, and Ricardo J. Ferrari. "Assessment of Linear and Non-linear Feature Projections for the Classification of 3-D MR Images on Cognitively Normal, Mild Cognitive Impairment and Alzheimer’s Disease." In Computational Science and Its Applications – ICCSA 2021. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-86960-1_2.

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Nobili Flavio, De Carli Fabrizio, Frisoni Giovanni B., et al. "The Value of SPECT in Detecting Alzheimer-Type Neurodegeneration in Mild Cognitive Impairment." In Advances in Alzheimer’s Disease. IOS Press, 2011. https://doi.org/10.3233/978-1-60750-793-2-205.

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Despite brain perfusion SPECT with technetium radiopharmaceuticals has not been formally included among the biomarkers for the early diagnosis of Alzheimer's disease (AD), its worldwide availability and the large literature evidence in AD and related disorders still make of it a valid alternative to FDG-PET, wherever the latter is unavailable. In this article, baseline brain SPECT has been evaluated in 80 subjects presenting with a cognitive complaint who have been followed for a mean of about two years, when twelve patients developed AD-dementia (AD-D), nineteen showed significant memory decl
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Maggio, Marcello, and Fulvio Lauretani. "Cognitive impairment (brain) and (et) dynapenia (D) “BED” in older persons." In Factors Affecting Neurological Aging. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-817990-1.00041-x.

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Yassi, Nawaf, Saima Hilal, Ying Xia, et al. "Influence of Comorbidity of Cerebrovascular Disease and Amyloid-β on Alzheimer’s Disease." In Handbook of Prevention and Alzheimer’s Disease. IOS Press, 2024. http://dx.doi.org/10.3233/aiad230036.

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Background: Quantifying the contribution of cerebrovascular disease to the clinical and pathological profile of Alzheimer’s disease is challenging. Objective: We aimed to determine the influence of cerebrovascular disease, amyloid-β (Aβ), and their comorbidity on cognitive decline, hippocampal atrophy, and Aβ deposition, by evaluating data from the Australian Imaging, Biomarker and Lifestyle Study of Ageing. Methods: Two-hundred and eighteen participants underwent Aβ PET, MRI, and cognitive assessment at 18-month intervals for up to 90 months. Aβ status was determined on baseline PET. Particip
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Janse, André, Ondine van de Rest, Lisette C. P. G. M. de Groot, and Renger F. Witkamp. "The Association of Vitamin D Status with Mild Cognitive Impairment and Dementia Subtypes: A Cross-Sectional Analysis in Dutch Geriatric Outpatients." In Handbook of Prevention and Alzheimer’s Disease. IOS Press, 2024. http://dx.doi.org/10.3233/aiad230018.

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Background: Vitamin D deficiency is associated with all-cause dementia and Alzheimer’s disease (AD). At the same time, this knowledge is limited specifically for vascular dementia (VaD), while data regarding other subtypes of dementia are even more limited. Objective: To investigate the association of 25-hydroxy vitamin D (25(OH)D) status with dementia subtypes in an outpatient geriatric population. Methods: In a cross-sectional design, we analyzed data from 1,758 patients of an outpatient memory clinic in The Netherlands. Cognitive disorders were diagnosed by a multidisciplinary team accordin
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Dönmez, Ceylan, Fatma Ayaz, and Nuraniye Eruygur. "Multiple Sclerosis (MS) and its Treatment with Natural Products." In Herbal Medicine for Autoimmune Diseases. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815305005124010010.

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Multiple sclerosis (MS) is an autoimmune disease that causes myelination defects and axonal impairment in the central nervous (CNS) system, causing inhibition of electrical transmission. The disease's typical symptoms include stiffness, persistent discomfort, exhaustion, motor and mobility problems, and cognitive deficits. Although immunosuppressive and immune-modulating medications have been the fundamental basis of MS treatment, there is currently no known treatment for the disease. Herbaloriginated therapies are now being considered a possible therapeutic option for MS by using medicinal pl
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Thomas, Sherine. "Post-Infection Syndrome." In Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198801740.003.0051.

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Post-infection syndrome (PIS) or chronic fatigue syndrome (CFS) is a complex debilitating disorder. It is usually characterized by fatigue that is worsened by physical activity or mental exertion, and is experienced in the aftermath, or with ongoing concurrent infections. Other symptoms may also be present including myalgia, impaired concentration, impaired memory, insomnia, and post-exertion malaise that can last for more than twenty-four hours after exertion. PIS/ CFS is a complex disorder with symptoms related to cognitive, autonomous, and immune dysfunction. No single causal factor has bee
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Dubey, Sonal, and Mahesh AR. "Tau Protein: Targets And Development Against Alzheimer’s Disease." In Enzymatic Targets for Drug Discovery Against Alzheimer's Disease. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815136142123010010.

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The clinical manifestations of Alzheimer's disease (AD) and associated human tauopathies are driven by tau neuronal and glial abnormalities. Tau, a microtubule-associated protein is inherently disordered due to its lack of a stable structure and great flexibility. Intracellular inclusions of fibrillar tau with a sheet shape accumulate in the brains of individuals with AD and other tauopathies. As a result, tau separation from microtubules and tau transition from a disordered state to an inappropriately aggregated state are critical steps before the start of tau-related illnesses. Many studies
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Wichert Reiner. "Introduction to Section on AAL for Rehabilitation." In Ambient Intelligence and Smart Environments. IOS Press, 2012. https://doi.org/10.3233/978-1-60750-837-3-495.

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Rehabilitation techniques in Ambient Assisted Living, which concentrates on supporting persons with special needs, is viewed as one of the most promising areas of AAL (Ambient Assisted Living). Thus these technologies for rehabilitation constitute a major research area within AAL research. A large number of new technologies have been developed in R&amp;amp;D projects for rehabilitation in recent years. Lots of project results in form of applications and prototypes have been developed. This section contains important work on technologies to support people with chronic obstructive pulmonary dise
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Schwarcz, Robert, and Sophie Erhardt. "Kynurenic acid in brain function and dysfunction." In Psychotic Disorders, edited by Michael A. P. Bloomfield and Oliver D. Howes. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190653279.003.0036.

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The essential amino acid tryptophan is degraded primarily by the kynurenine pathway, a cascade of enzymatic steps leading to the generation of several neuroactive compounds. Of those, kynurenic acid (KYNA), an antagonist at N-methyl-D-aspartate (NMDA) and alpha7-nicotinic receptors, has gained much attention in schizophrenia research. The concentrations of both KYNA and its precursor, kynurenine, have been repeatedly found significantly elevated both in the postmortem cerebral cortex and in the cerebrospinal fluid of schizophrenia persons as compared to healthy control subjects. Studies in exp
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Conference papers on the topic "D cognitive impairment"

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Lu, Hsuan-yu, Zhongping Ye, Chun Hang Ti, et al. "Design a Rehabilitation Platform to Improve Mild Cognitive Impairment by Integrating Cognitive Training Games with Moderate-intensity Cycling Exercise." In 15th International Conference on Applied Human Factors and Ergonomics (AHFE 2024). AHFE International, 2024. http://dx.doi.org/10.54941/ahfe1004902.

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Most studies recognized motor-cognitive dual-task training as an effective treatment to enhance neurological disorders in patients with improved motor and cognitive performance. However, the practical treatment strategy of motor-cognitive dual-task training still need to be confirmed with the clinical evidence-based support. The purpose of this study aimed to propose the optimal strategy of dual-task training using moderate-intensity stationary cycling and multidomain cognitive training for patients with MCI, and compare the post-training performance between motor, cognitive and motor-cognitiv
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Soares, Carolina, Débora G. Souza, Andreia Silva da Rocha, Luiza Machado, Bruna Bellaver, and Eduardo R. Zimmer. "BRAIN ENERGETICS EVALUATION IN EARLY STAGES OF AMYLOID PATHOLOGY IN A RAT MODEL OF ALZHEIMER’S DISEASE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda086.

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Background: Transgenic models of Alzheimer’s disease (AD) overexpress human APP, PS1 or PS2 mutations. These models present amyloid-beta pathology but do not recapitulate the complexity of AD. Interestingly, the transgenic rat model TgF344-AD, which overpresses human APP and PS1 mutations, seems to follow a more similar disease progression, manifesting progressive tau tangle-like pathology and late cognitive impairment. Yet, whether they develop energy metabolism changes as we see in AD remains unclear. Objective: Here, we investigated brain bioenergetics in 6-7 months F344-AD/WT rats, an age
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Nery, Julia Pio Fernandes, Kaisy Nagella Alves, Victor Teatini Ribeiro, and Antônio Pereira Gomes. "Anti-N-Methyl D-Aspartate (NMDA) receptor encephalitis after herpes virus meningoencephalitis: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.681.

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Anti-N-methyl D-aspartate (NMDA) receptor encephalitis is an autoimmune disease of the central nervous system characterized by psychiatric and neurological symptoms. This pathology may be associated with paraneoplastic syndrome and viral infections, especially the Herpes simplex virus. However, a considerable number of cases may remain without an identifiable triggering factor. We report the case of a 17-year-old girl who presented with headache, fever and meningeal signs. Cerebrospinal fluid (CSF) analysis showed a herpes virus infection. After treatment using Acyclovir for 21 days, the patie
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Clayton, Erik H., and Philip V. Bayly. "Brain Response to Extracranial Acoustic Loads: Shear Wave Propagation Characterized by Vector Fields." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-63245.

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Traumatic brain injuries (TBI) due to blast are common in modern combat situations, and often lead to permanent cognitive impairment. Despite the prevalence and severity of blast-induced TBI, the condition remains poorly understood. Computer simulations of blast and blast injury mechanics offer enormous potential; however, computer models require accurate descriptions of tissue mechanics and boundary conditions in vivo. To gain insight into the mechanisms of blast injury, we applied direct (light) oscillatory pressure loading to the skulls of human volunteers, and measured displacement and str
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Krayem, Zainab, Rachel Jeff-Macauley, Nicolette Falco, and Vanesa Pizutelli. "Addressing the Health Needs of the (D/d)eaf and Hard of Hearing Community." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.163_2023.

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The term deaf refers to individuals with total or partial hearing loss. However, it encompasses much more, representing a culture—Deaf culture. The distinction in spelling is important: "Deaf," with an uppercase "D," refers to individuals born Deaf who have been raised within Deaf culture, while "deaf," with a lowercase "d," typically refers to those who lost their hearing later in life and may not have grown up in Deaf culture. People who identify as deaf, Deaf, or hard of hearing (d/D/hoh) are often mistakenly assumed to have cognitive impairments or are broadly categorized as disabled. Howe
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Mccarthy, Randal. "Human Factors Engineering and User- centered Design Principles in the Design and Development of Device Combination Products for Special Patients Populations." In 16th International Conference on Applied Human Factors and Ergonomics (AHFE 2025). AHFE International, 2025. https://doi.org/10.54941/ahfe1006189.

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The US Food and Drug Administration (US FDA) is a global leader in the regulation of device combination products and founded the Office of Combination Products (OCP) in December 2002, Combination products range from physical or chemical combinations to products packaged together and separately packaged products that need to be used together. The OCP has developed many policies and guidance, in particular, the US FDA Human Factor Guidance, the regulatory lens for this paper (1, 2). In the Combination Product Human Factors component, the US FDA, similar to other leading agencies, in Europe, Chin
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