Academic literature on the topic 'Damage spleen'

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Journal articles on the topic "Damage spleen"

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Chen, Haoxiang, Feiyao Wang, Xingyue Wu та ін. "Chronic Heat Stress Induces Oxidative Stress and Induces Inflammatory Injury in Broiler Spleen via TLRs/MyD88/NF-κB Signaling Pathway in Broilers". Veterinary Sciences 11, № 7 (2024): 293. http://dx.doi.org/10.3390/vetsci11070293.

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The spleen is the largest peripheral immune organ of the organism, accounting for 25% of the total lymphoid tissue of the body. During HS, the spleen is damaged due to the elevated environment, which seriously affects life performance and broilers’ health. This study aimed to investigate the mechanism of chronic HS damage to broiler spleen tissues. The broilers were typically raised until they reached 21 days of age, after which they were arbitrarily allocated into two groups: an HS group and a cntrol group. The HS group was subjected to a temperature of 35 °C for 10 h each day, starting at 21
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Ulaş, Mustafa. "Valproic Acid Attenuates Oxidative Damage in Rat Spleen Tissue Induced By Spinal Cord Damage." Turkish Journal of Agriculture - Food Science and Technology 10, sp2 (2022): 3054–56. http://dx.doi.org/10.24925/turjaf.v10isp2.3054-3056.5802.

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Events such as oxidative stress caused by spinal cord injury (SCI) are a serious condition because they negatively affect many organs. Alternative treatment options for this type of injury are quite limited. In this study, we planned to investigate the effect of oxidative damage on the spleen tissue of rats with spinal cord damage and the protective role of valproic acid (VPA) in this damage. Sixteen Wistar albino rats were divided into two equal groups. No treatment was administered to the rats in Group 1 (SCI-(Control), but a single dose of 300 mg/kg intraperitoneally VPA was administered to
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Kit, Oleg, Yevgeniy Kolesnikov, Mikhail Kozhushko, and Aleksandr Snezhko. "A RARE CASE OF METASTASIS OF GASTRIC CANCER IN THE SPLEEN." Problems in oncology 63, no. 1 (2017): 153–54. http://dx.doi.org/10.37469/0507-3758-2017-63-1-153-154.

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The spleen’s damage by metastases of malignant tumors is occasional. There is presented a clinical observation of rare isolated metastasis of gastric cancer in the spleen without concomitant dissemination that is interesting.
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Ding, Rui, Han Huang, Hongyu Wang, et al. "Goose Nephritic Astrovirus Infection of Goslings Induces Lymphocyte Apoptosis, Reticular Fiber Destruction, and CD8 T-Cell Depletion in Spleen Tissue." Viruses 13, no. 6 (2021): 1108. http://dx.doi.org/10.3390/v13061108.

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The emergence of a novel goose nephritic astrovirus (GNAstV) has caused economic losses to the Chinese goose industry. High viral load is found in the spleen of goslings infected with GNAstV, but pathological injuries to the spleen due to GNAstV are largely unknown. In this study, 50 two-day-old goslings were infected orally with GNAstV, and 50 goslings were treated with PBS as control. Spleens were collected at different times following infection to assess damage. GNAstV infection caused visceral gout and urate deposition in joints, and resulted in 16% mortality. GNAstV was found in the lymph
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Li, Xiaocong, Xin Zeng, Wanqin Yang, Peng Ren, Hengxiao Zhai, and Heng Yin. "Impacts of Copper Deficiency on Oxidative Stress and Immune Function in Mouse Spleen." Nutrients 17, no. 1 (2024): 117. https://doi.org/10.3390/nu17010117.

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Introduction: Copper is an essential trace element crucial for enzyme synthesis and metabolism. Adequate copper levels are beneficial for maintaining the normal immune function of the spleen. Copper deficiency disrupts the metabolic processes within the spleen and impairs its immune function. This research examines the impact of copper deficiency on the spleen and the potential recovery following copper supplementation. Methods: Weaned mice underwent a 4-week copper-deficient diet, succeeded by 1-week of copper repletion via intraperitoneal copper sulfate injection. Histological examination wa
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Ali, Asma Basharat, Nadia Younus, Sahrish Mukhtar, Lubna Faisal, Tayyaba Kazmi, and Alina Atif. "Evaluating Vitamin E's Antioxidative Effect on Carbamazepine-Induced Spleen Damage in Rat Models." Pakistan Journal of Medicine and Dentistry 13, no. 3 (2024): 132–39. https://doi.org/10.36283/pjmd13-3/018.

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Background: The spleen is essential for the body’s homeostasis and immune system. Carbamazepine (CBZ) is known to cause toxicity to several organs, including the spleen, through oxidative stress, however, vitamin E (Vit E) is a proven antioxidant against toxins. Thus, this study evaluated the antioxidative effect of Vit E on hematological and splenic toxic changes, caused by carbamazepine in rats. Methods: This in-vivo preclinical experimental study was conducted from March-June 2020, at Jinnah Medical and Dental College, Karachi. Forty adult male rats, weighing 150-200 grams were included and
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Hildebrand, P., U. J. Roblick, E. Schlöricke, R. Czymek, H. P. Bruch, and C. Bürk. "The role of organ preservation in the surgical therapy of traumatic spleen injury." Acta chirurgica Iugoslavica 58, no. 4 (2011): 21–25. http://dx.doi.org/10.2298/aci1104021h.

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Background: New findings on immunological und haematological functions of the spleen, the postoperative risks following splenectomy, as well as improved surgical techniques resulted in an increased interest in organ preservative surgery after traumatic spleen injury in recent years. Material and Methods: The data of all patients who un-derwent surgery for traumatic spleen injuries between 1995 - 2009 were recorded prospectively and analyzed concerning type of operation, intra-and postoperative complications and the postoperative course. Results: A total of 214 patients with splenic trauma unde
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Zhang, T., Q. Zhao, Y. Zhang, and J. Ning. "Assessment of genotoxic effects of flumorph by the comet assay in mice organs." Human & Experimental Toxicology 33, no. 3 (2013): 224–29. http://dx.doi.org/10.1177/0960327111417268.

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The present study investigated the genotoxic effects of flumorph in various organs (brain, liver, spleen, kidney and sperm) of mice. The DNA damage, measured as comet tail length (µm), was determined using the alkaline comet assay. The comet assay is a sensitive assay for the detection of genotoxicity caused by flumorph using mice as a model. Statistically significant increases in comet assay for both dose-dependent and duration-dependent DNA damage were observed in all the organs assessed. The organs exhibited the maximum DNA damage in 96 h at 54 mg/kg body weight. Brain showed maximum DNA da
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Sefc, Ludek, Ko-Tung Chang, Viktor Sykora, and Emanuel Necas. "Mobilization with Cyclophosphamide Shifts Hematopoiesis From the Bone Marrow to the Spleen In Mouse." Blood 116, no. 21 (2010): 1590. http://dx.doi.org/10.1182/blood.v116.21.1590.1590.

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Abstract Abstract 1590 Introduction: Spleen is an active hematopoietic tissue in adult mice. Spleen niches supporting hematopoiesis were not extensively studied yet. Spleen does not contain osteoblastic niches which are considered to be essential for long-term hematopoiesis, and splenic hematopoiesis is assumed to originate mainly from progenitors with short-term repopulating ability. Normal spleen is primarily a lymphoid organ but it also contributes to myelopoiesis by containing approximately 5% of total body multipotent progenitors CFU-S. We have studied the effect of mobilization with cycl
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Baraaj, Abed Hassan, and Harith Jabbar Fahad Al-Mathkhury. "Histopathological changes in Spleen caused by Pseudomonas aeruginosa DNA." Greener Journal of Biological Sciences 3, no. 8 (2013): 319–24. https://doi.org/10.15580/gjbs.2013.8.060913819.

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Upon its release due to cell lysis, bacterial DNA has the ability to stimulate the immune system causing serious damage in tissue. Intraperitoneally injection of&nbsp;<em>P. aeruginosa</em>&nbsp;DNA in rats caused several histopathological changes in the splenic tissue included; a marked germinal center hyperplasia in the white pulp which results in the increase of follicles number within germinal center. Furthermore, apoptotic debris engulfed by macrophages in the marginal zone was noticed. Hemosiderin and degenerated cells were observed as well. In a conclusion, even though the bacterial cel
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Dissertations / Theses on the topic "Damage spleen"

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Пак, Василь Якович, Василий Яковлевич Пак, Vasyl Yakovych Pak та В. А. Полторацький. "Діагностика і лікування травматичного ушкодження селезінки". Thesis, Видавництво СумДУ, 2003. http://essuir.sumdu.edu.ua/handle/123456789/9348.

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Walz, Paul S. "Influence of pathogenic bacterial determinants on genome stability of exposed intestinal cells and of distal liver and spleen cells." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Biology, c2011, 2011. http://hdl.handle.net/10133/3405.

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Most bacterial infections can be correlated to contamination of consumables such as food and water. Upon contamination, boil water advisories have been ordered to ensure water is safe to consume, despite the evidence that heat-killed bacteria can induce genomic instability of exposed (intestine) and distal cells (liver and spleen). We hypothesize that exposure to components of heat-killed Escherichia coli O157:H7 will induce genomic instability within animal cells directly and indirectly exposed to these determinants. Mice were exposed to various components of dead bacteria such as DNA, RNA, p
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CUFFARO, VINCENZO. "Prediction Method for the Surface Damage in Splined Couplings." Doctoral thesis, Politecnico di Torino, 2013. http://hdl.handle.net/11583/2506323.

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The primary purpose of my PhD thesis was to develop design criteria and to verify procedures about fretting wear, that are applicable to crowned spline couplings of a power transmission system of the aeroengines. Fretting is a very complex phenomenon being influenced by many factors, the most important being the presence or absence of lubrication, the load distribution (contact pressure) and the sliding between the bodies. Therefore, the study of fretting needs a deep knowledge of these three main aspects. The first aspect of the problem was based on models and experimental tests considering s
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Books on the topic "Damage spleen"

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Bunch, Chris. Splenomegaly and other disorders of the spleen. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0035.

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The spleen is a predominantly lymphoid organ, normally about the size of a clenched fist located beneath the diaphragm in the left upper abdomen. It has a dual role as a filter for the circulation, and a primary lymphoid organ in its own right. About three-quarters of its volume is a matrix of capillaries and sinuses (the red pulp), through which blood is able to percolate slowly and come into contact with fixed macrophages, which are able to remove senescent or damaged red cells, or other particulate matter such as bacteria. The lymphoid tissue is organized into scattered follicles (the white
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Book chapters on the topic "Damage spleen"

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Brink, Anita, Zvi Bar-Sever, and Lorenzo Biassoni. "Liver and Spleen." In A Practical Guide for Pediatric Nuclear Medicine. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-67631-8_7.

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AbstractNuclear medicine studies for the evaluation of liver, spleen, and biliary tract pathologies include a number of tests performed with various radiotracers. These imaging modalities are based on an assessment of the various histological components of the liver and spleen and their functional characteristics. Hepatobiliary scintigraphy (HBS) evaluates the function of the hepatocytes and the biliary system. Liver and spleen scintigraphy with [99mTc]-labelled colloid tracks active tracer phagocytosis by the reticuloendothelial system (RES) of the liver, spleen, and bone marrow. Approximatel
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Palanci, Ozgur. "The Splen." In Clinical Anatomy of Digestive System a Handbook for Healthcare Professionals. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358855.8.

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In this section, the anatomy of the spleen is examined in detail. The spleen is one of the most important organs of our body and acts as an important part of the hematopoietic system and the immune system. It also plays an important role in storing and filtering blood and producing various blood cells. Anatomically, the spleen is roughly divided into two parts: the white pulp and the red pulp. The white pulp contains cells of the immune system and represents an important site for antibody production. The red pulp is responsible for filtering blood cells and recovering the reusable components o
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Shen, Yong Jun, Shao Pu Yang, and Bing Yu Ma. "Application of Fractional Spline Wavelet in Detection of Abrupt Information from Fault Gear System." In Fracture and Damage Mechanics V. Trans Tech Publications Ltd., 2006. http://dx.doi.org/10.4028/0-87849-413-8.371.

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Powers, Amy, Leslie Silberstein, and Frank J. Strobl. "Haemolytic anaemia—congenital and acquired." In Oxford Textbook of Medicine. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199204854.003.220509.

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Premature destruction of red cells occurs through two primary mechanisms: (1) decreased erythrocyte deformability that leads to red-cell sequestration and extravascular haemolysis in the spleen and other components of the reticuloendothelial system—may be caused by membrane defects, metabolic abnormalities, exogenous oxidizing agents, or pathological antibodies; (2) red-cell membrane damage and intravascular haemolysis—may be caused by exposure to pathological antibodies, activated complement, mechanical forces, chemicals, and infectious agents....
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Klaas, James P., and Robert D. Brown. "Cerebrovascular Diseases." In Mayo Clinic Internal Medicine Board Review. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190464868.003.0053.

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Acute and chronic interstitial inflammation can result in injury to renal tubules, leading to tubular dysfunction and, chronically, tubular atrophy. Causes of chronic tubulointerstitial damage include autoimmune and hereditary causes, analgesic nephropathy, uric acid, lithium, heavy metals, mercury, lead, and oxalate. Autosomal dominant polycystic kidney disease is the most common hereditary renal disease. It occurs in both males and females and is characterized by multiple bilateral renal cysts and cysts in other organs (eg, liver, spleen, and pancreas).
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Mirza, Ahmad, Rafik Filobbos, Ambareen Kausar, and Derek A. O’Reilly. "Injury to the liver, pancreas, spleen, gallbladder, and extra-hepatic bile duct." In Abdominal Trauma, Peritoneum, and Retroperitoneum, edited by Aditya J. Nanavati, Sanjay Nagral, Samiran Nundy, and Dirk J. Gouma. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/med/9780192862433.003.0003.

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Abstract Abdominal trauma can cause significant injury to the liver, pancreas, gallbladder, and spleen. In recent decades, there has been a paradigm shift from surgical treatment of these injuries to a conservative, non-operative approach, including angioembolization. When laparotomy is performed for liver trauma, damage control manoeuvres, including peri-hepatic packing, form the mainstay of the initial strategy. For pancreatic trauma, the key distinction for clinical purposes is whether a main pancreatic ductal injury is present. A non-operative approach is preferred when the main pancreatic
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Marilyn, Weaver Lewis, Wu Liyun, and Allan Hagen Zachary. "How Understanding the Lymphatic System Can Benefit Mental Health Clinicians." In STEM-H for Mental Health Clinicians. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/oso/9780197638514.003.0004.

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Abstract STEM-H for Mental Health Clinicians, Chapter 4, covers the structure and function of the lymphatic system in regard to STEM-H (science, technology, engineering, and mathematics as applied to health). Signature illnesses covered are human immunodeficiency virus positivity (HIV) and acquired immune deficiency syndrome (AIDS). The signature injury is damage to the spleen caused by blunt force trauma. Female condoms are presented as a technological innovation associated with prevention of HIV and AIDS. Biomedical and pharmaceutical engineering concepts explain the action of highly active
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Klimova, Elena, Larisa Drozdova, Olena Lavinska, Sergey Sushkov, and Valery Boyko. "Perspective Chapter: Specific predictors of the autoimmune reactions formation in case of immunocompetent organs damage in patients with myasthenia gravis and hepatosplenomegaly." In Causes and Diagnosis of Autoimmune Diseases [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.1002972.

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The urgency of the problem is determined by the increasing prevalence and rapid progression of autoimmune diseases and autoimmune components in various nosologies. The aim is to study individual trigger factors, predictors of development, and the condition severity markers to substantiate complex treatment, including surgical tactics and the therapeutic target choice, in case of the immunocompetent organs (thymus and spleen) damage. In patients with myasthenia gravis the trigger markers were identified: the presence of herpes viruses persistence and mycoplasma; the relationship of certain huma
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Ideguchi, Hiroshi. "Hereditary Spherocytosis." In Clinical Studies In Medical Biochemistry. Oxford University PressNew York, NY, 2006. http://dx.doi.org/10.1093/oso/9780195147322.003.0006.

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Abstract A 25-year-old Japanese man was admitted to the hospital because of fever, sore throat, and general malaise. He had been febrile for several days and had noticed that the color of his urine was unusually dark. On admission, his temperature was 37.8°C. The physician noted anemic conjunctiva (delicate membrane lining the eyelids and covering the eyeballs), injected pharyngeal mucosa (mucous membrane), cervical lymphadenopathy (swelling of the lymph nodes), and mild splenomegaly (enlargement of the spleen). Barr virus confirmed that he had infectious mononucleosis. He was kept in bed for
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Peng, Ying, Shubei He, and Ning Kang. "Noninvasive Diagnostic Methods in Liver Cirrhosis." In Liver Cirrhosis - Advances in Diagnosis and Management [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1005324.

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Liver cirrhosis is a condition characterized by the gradual development of liver fibrosis and the disruption of hepatic lobules. Patients who have decompensated cirrhosis face a significant risk of severe complications, including ascites, esophageal varices, liver failure, and hepatocellular carcinoma. Early diagnosis and timely intervention are crucial to preventing further liver damage, reducing morbidity and mortality associated with complications, and improving the prognosis. Additionally, timely diagnosis and accurate assessment of liver cirrhosis are critical for effective management and
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Conference papers on the topic "Damage spleen"

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Cheng, Cuilin, Zhenyu Wang, Haitian Zhao, Aiju Hou, Rongchun Wang, and Lei Yao. "UVC-induced damage in mouse spleen lymphocytes and anti-radiation effect of exogenous nucleotides." In International conference on Human Health and Medical Engineering. WIT Press, 2014. http://dx.doi.org/10.2495/hhme131172.

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Ali Mohammed, Imtithal. "Protective Role of Cranberry Extract Against Zovirax-Induced Spleen Dysfunction in Adult Female Wistar Rats." In XI. International Scientific Congress of Pure, Applied and Technological Sciences (MINAR Congress). Rimar Academy, 2024. https://doi.org/10.47832/minarcongress11-8.

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This research explored a possible protective function of antioxidants, such as cranberries, against zoviraxinduced spleen dysfunction in adult female Wistar rats. A collection of 24(adult female Wistar rats) was haphazardly appointed to four equal sets, each including six animals. They received the following treatment for (0–22–44) days per day. The first group, known as group (C), was obtained in (tap water), and served as a control. The second set (A1) obtained orally 150 mg/kg B.W. of cranberry alone. The third group (A2) received zovirax (450mg/kg B.W.) during the trial to elicit spleen to
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Kusano, Kristofer D., and Hampton C. Gabler. "Quantitative Crash Injury Risk Predictions by Body Region: Is Risk Sensitive to New Vehicle Safety Features?" In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80301.

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Retrospective examinations of real-world injury data is often used to evaluate injury risk for exposure to hazards, e.g. car crashes. In studying injury resulting from passenger vehicle crashes, there are several sources of real-world data that contain information about the crashes (e.g. vehicle damage, impact speeds) as well as occupant injury outcome. These real-world crash databases are used, for example, to study risk of traumatic brain injury, countermeasure opportunities for far-side occupants in side impact, and spleen injury for different restraint types [1–3].
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AN, SHUO, XUEJIAO MA, FANGDONG DONG, WENMIN YAN, and TIANLONG ZHANG. "STUDY ON BLUNT IMPACT DEFECT OF BIONIC UPPER HUMAN TORSO." In 32ND INTERNATIONAL SYMPOSIUM ON BALLISTICS. Destech Publications, Inc., 2022. http://dx.doi.org/10.12783/ballistics22/36199.

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In order to explore the injury mechanism of human upper torso under soft protection, ballistic tests were carried out to simulate blunt effect of target on upper torso of bionic dummy under soft protection. Acceleration, pressure, force and other parameters are used to reflect the biological characteristics and injuries of human body under blunt impact effect. The acceleration, pressure, force and other parameters of each part were recorded by impacting the heart, liver, left and right lungs and spleen and stomach at five bullet speeds. Through comparative analysis of different parts of the in
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George, Stephanie M., Diego R. Martin, and Don P. Giddens. "Contribution of Superior Mesenteric Vein Flow to the Right and Left Lobes of the Liver Using CFD." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206254.

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The incidence of cirrhosis, the end stage for many liver diseases, is rising and with it the need for better understanding of the progression of the disease and diagnostic techniques. The authors have noted that liver disease occurs preferentially in the right side of the liver which is the largest lobe. One hypothesis is that this is due to the composition of the blood that supplies the right lobe. The liver is fed by both the hepatic artery and the portal vein with the portal vein contributing about 80% of the blood supply. The portal vein (PV) is supplied by the superior mesenteric vein (SM
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Villa, P., and M. Gianinetto. "Multispectral Transform and Spline Interpolation for Mapping Flood Damages." In 2006 IEEE International Symposium on Geoscience and Remote Sensing. IEEE, 2006. http://dx.doi.org/10.1109/igarss.2006.75.

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Pham, D. C., Xiaodong Cui, Jim Lua, and Vijay Goyal. "High-fidelity Progressive Damage Predictions of Composite T-joints using Advanced Continuum Damage Model and B-Spline Analysis Method." In AIAA Scitech 2021 Forum. American Institute of Aeronautics and Astronautics, 2021. http://dx.doi.org/10.2514/6.2021-0703.

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Maia, Fernanda Pimentel Arraes, Eduarda Sousa Machado, Fabiana Germano Bezerra, Brenda Regio Garcia, and Luiz Gonzaga Porto Pinheiro. "LIVER TRANSPLANTATION IN A FEMALE PATIENT WITH PREVIOUS HISTORY OF BREAST CANCER." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1052.

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Bile duct injury is a complication of cholecystectomy and may lead the patient to develop secondary biliary cirrhosis (SBC), an irreversible damage to the liver parenchyma caused by the chronic interruption of bile flow. Clinically, cirrhosis manifests when 80% of the liver parenchyma is affected with symptoms like pruritus, jaundice, coagulopathy, and ascites in advanced stages. Liver transplantation is an option of the treatment for SBC, especially when its progression leads to liver failure but there are conditions that strongly contraindicate the procedure, such as an active extrahepatic m
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Zuo, Hao, Xuefeng Chen, Zhibo Yang, and Laihao Yang. "Modeling of Lamb Wave Propagation in Beam-Like Structures via Wavelet Finite Element Method." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65366.

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Beam-like structure is known as one of crucial engineering structures in practical application of aerospace, vessel, civil and machinery. The damages have a great influence on machine performance and may cause a serious threat for security of mechanical structures and systems. Thus it is very significant to identify the damage of beam-like structures for security of mechanical structures and systems. This paper presents a novel application of wavelet finite element method (WFEM) in Lamb wave propagation of beam-like structures. The WFEM, adopting excellent B-spline wavelet on interval (BSWI) b
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Schaff, J. R., and R. Y. Kim. "Damage Initiation and Progression in Multidirectional Laminates With a Hole." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-1197.

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Abstract Holes are pervasive in load-bearing composite structures within the aerospace industry, as a result of the use of mechanical fasteners in assembly and cutouts to accommodate wiring and hydraulic lines. In this work, static loading experiments were conducted on composite laminates to document the initiation and growth of damage and to record changes in the strain field. The main objective of this work was the development of an experimental database for comparison with the results from a three-dimensional stress analysis based on spline variational theory. Two multidirectional laminates
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