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1

Finizio, F. S., and E. Galassi. "Ematomi extradurali nell'infanzia e nell'adolescenza." Rivista di Neuroradiologia 5, no. 1_suppl (1992): 45–50. http://dx.doi.org/10.1177/19714009920050s109.

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Gli autori descrivono i principali aspetti TC della loro casistica di 21 EED dell'infanzia e dell'adolescenza, tutti sottoposti a verifica chirurgica, osservati nella Divisione di Neurochirurgia II dell'Ospedale Bellaria di Bologna dal 1985 al 1990. Gli EED sono risultati più frequenti rispetto agli ematomi sottodurali acuti e cronici (8 casi). La possibile presenza di un EED in assenza di fratture craniche è più alta in età pediatrica rispetto a quella adulta: in 4/21 (20%) dei nostri casi non erano riscontrabili fratture all'esame diretto del cranio. La localizzazione esclusivamente frontale
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2

Vulesevic, B., and S. F. Perry. "Developmental plasticity of ventilatory control in zebrafish, Danio rerio." Respiratory Physiology & Neurobiology 154, no. 3 (2006): 396–405. http://dx.doi.org/10.1016/j.resp.2006.01.001.

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3

Vulesevic, B. "Chemoreceptor plasticity and respiratory acclimation in the zebrafish Danio rerio." Journal of Experimental Biology 209, no. 7 (2006): 1261–73. http://dx.doi.org/10.1242/jeb.02058.

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4

Schaefer, J., and A. Ryan. "Developmental plasticity in the thermal tolerance of zebrafish Danio rerio." Journal of Fish Biology 69, no. 3 (2006): 722–34. http://dx.doi.org/10.1111/j.1095-8649.2006.01145.x.

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5

Engeszer, Raymond E., Laura Alberici Da Barbiano, Michael J. Ryan, and David M. Parichy. "Timing and plasticity of shoaling behaviour in the zebrafish, Danio rerio." Animal Behaviour 74, no. 5 (2007): 1269–75. http://dx.doi.org/10.1016/j.anbehav.2007.01.032.

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Roy, Tamal, and Robert Arlinghaus. "Size-selective mortality fosters ontogenetic changes in collective risk-taking behaviour in zebrafish, Danio rerio." Oecologia 200, no. 1-2 (2022): 89–106. http://dx.doi.org/10.1007/s00442-022-05256-y.

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AbstractSize-selective mortality is common in fish populations and can operate either in a positive size-selective fashion by harvesting larger-than-average fish or be negatively size-selective by harvesting smaller-than-average fish. Through various mechanisms (like genetic correlations among behaviour and life-history traits or direct selection on behaviour co-varying with growth rate or size-at-maturation), size-selection can result in evolutionary changes in behavioural traits. Theory suggests that both positive and negative size-selection without additional selection on behaviour favours
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Bhat, Anuradha, Melissa M. Greulich, and Emília P. Martins. "Behavioral Plasticity in Response to Environmental Manipulation among Zebrafish (Danio rerio) Populations." PLOS ONE 10, no. 4 (2015): e0125097. http://dx.doi.org/10.1371/journal.pone.0125097.

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8

Simmonds, Alec I. M., and Frank Seebacher. "Histone deacetylase activity modulates exercise-induced skeletal muscle plasticity in zebrafish (Danio rerio)." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 313, no. 1 (2017): R35—R43. http://dx.doi.org/10.1152/ajpregu.00378.2016.

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Aerobic exercise has a positive impact on animals by enhancing skeletal muscle function and locomotor performance. Responses of skeletal muscle to exercise involve changes in energy metabolism, calcium handling, and the composition of contractile protein isoforms, which together influence contractile properties. Histone deacetylases (HDAC) can cause short-term changes in gene expression and may thereby mediate plasticity in contractile properties of skeletal muscle in response to exercise. The aim of this project was to determine (in zebrafish, Danio rerio) the traits that mediate interindivid
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Georga, Ioanna, and George Koumoundouros. "Thermally induced plasticity of body shape in adult zebrafish Danio rerio (Hamilton, 1822)." Journal of Morphology 271, no. 11 (2010): 1319–27. http://dx.doi.org/10.1002/jmor.10874.

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10

Hosseini, Shahrbanou, Bertram Brenig, Jens Tetens, and Ahmad Reza Sharifi. "Phenotypic plasticity induced using high ambient temperature during embryogenesis in domesticated zebrafish, Danio rerio." Reproduction in Domestic Animals 54, no. 3 (2018): 435–44. http://dx.doi.org/10.1111/rda.13382.

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11

Robertson, Cayleih E., Patricia A. Wright, Louise Köblitz, and Nicholas J. Bernier. "Hypoxia-inducible factor-1 mediates adaptive developmental plasticity of hypoxia tolerance in zebrafish, Danio rerio." Proceedings of the Royal Society B: Biological Sciences 281, no. 1786 (2014): 20140637. http://dx.doi.org/10.1098/rspb.2014.0637.

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In recent years, natural and anthropogenic factors have increased aquatic hypoxia the world over. In most organisms, the cellular response to hypoxia is mediated by the master regulator hypoxia-inducible factor-1 (HIF-1). HIF-1 also plays a critical role in the normal development of the cardiovascular system of vertebrates. We tested the hypothesis that hypoxia exposures which resulted in HIF-1 induction during embryogenesis would be associated with enhanced hypoxia tolerance in subsequent developmental stages. We exposed zebrafish ( Danio rerio ) embryos to just 4 h of severe hypoxia or total
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12

Schmidt, Kai, and J. Matthias Starck. "Developmental plasticity, modularity, and heterochrony during the phylotypic stage of the zebra fish,Danio rerio." Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 9999B (2009): n/a. http://dx.doi.org/10.1002/jez.b.21320.

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13

Pan, Tien-Chien Francis, and Ione Hunt von Herbing. "Metabolic plasticity in development: Synergistic responses to high temperature and hypoxia in zebrafish, Danio rerio." Journal of Experimental Zoology Part A: Ecological and Integrative Physiology 327, no. 4 (2017): 189–99. http://dx.doi.org/10.1002/jez.2092.

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14

Yaqoob, Nadeem, and Thorsten Schwerte. "Cardiovascular and respiratory developmental plasticity under oxygen depleted environment and in genetically hypoxic zebrafish (Danio rerio)." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 156, no. 4 (2010): 475–84. http://dx.doi.org/10.1016/j.cbpa.2010.03.033.

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15

Craig, Paul M., Chris M. Wood, and Grant B. McClelland. "Gill membrane remodeling with soft-water acclimation in zebrafish (Danio rerio)." Physiological Genomics 30, no. 1 (2007): 53–60. http://dx.doi.org/10.1152/physiolgenomics.00195.2006.

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Little is known regarding the ionoregulatory abilities of zebrafish exposed to soft water despite the popularity of this model organism for physiology and aquatic toxicology. We examined genomic and nongenomic changes to gills of zebrafish as they were progressively acclimated from moderately hard freshwater to typical soft water over 7 days and held in soft water for another 7 days. Gills were sampled daily and mRNA expression levels of gill Na+-K+-ATPase (NKA) α1a subunit, epithelium calcium channel (ECaC), carbonic anhydrase-1 and 2 (CA-1, CA-2), Na+/H+ exchanger (NHE-2), V-type proton (H+)
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Forbes, Erin L., Craig D. Preston, and P. Mark Lokman. "Zebrafish (Danio rerio) and the egg size versus egg number trade off: effects of ration size on fecundity are not mediated by orthologues of the Fec gene." Reproduction, Fertility and Development 22, no. 6 (2010): 1015. http://dx.doi.org/10.1071/rd09257.

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Few studies have demonstrated plasticity of egg size within the confines of an egg size–number trade-off in response to trophic conditions in fishes. Moreover, the physiological mechanisms that govern this plasticity are not known. Growth differentiation factor 9 (Gdf9) and bone morphogenetic factor 15 (Bmp15) are oocyte-specific factors implicated in follicular growth and ovulation in mammals. In order to investigate whether expression levels of these genes were correlated with ration-dependent changes in fecundity in fish, zebrafish (Danio rerio) were subjected to four different feeding regi
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Morgan, Rachael, Mette H. Finnøen, Henrik Jensen, Christophe Pélabon, and Fredrik Jutfelt. "Low potential for evolutionary rescue from climate change in a tropical fish." Proceedings of the National Academy of Sciences 117, no. 52 (2020): 33365–72. http://dx.doi.org/10.1073/pnas.2011419117.

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Climate change is increasing global temperatures and intensifying the frequency and severity of extreme heat waves. How organisms will cope with these changes depends on their inherent thermal tolerance, acclimation capacity, and ability for evolutionary adaptation. Yet, the potential for adaptation of upper thermal tolerance in vertebrates is largely unknown. We artificially selected offspring from wild-caught zebrafish (Danio rerio) to increase (Up-selected) or decrease (Down-selected) upper thermal tolerance over six generations. Selection to increase upper thermal tolerance was also perfor
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18

Uusi-Heikkilä, S., A. Kuparinen, C. Wolter, T. Meinelt, A. C. O'Toole, and R. Arlinghaus. "Experimental assessment of the probabilistic maturation reaction norm: condition matters." Proceedings of the Royal Society B: Biological Sciences 278, no. 1706 (2010): 709–17. http://dx.doi.org/10.1098/rspb.2010.1507.

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The probabilistic maturation reaction norm (PMRN) describes an individual's probability of maturing at a given age as a function of size and other relevant phenotypic traits. Population-level shifts in the PMRN are often interpreted to indicate genetic as opposed to phenotypic changes in maturation in fish. Inferences derived from trends in the PMRN have been challenged, warranting an experimental assessment of the method. This was accomplished in a laboratory experiment using zebrafish ( Danio rerio ). Fish were reared under different food levels to induce variation in growth and maturation.
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19

Cacialli, Pietro, Serena Ricci, Maurizio Lazzari, Liliana Milani, and Valeria Franceschini. "Transcription Pattern of Neurotrophic Factors and Their Receptors in Adult Zebrafish Spinal Cord." International Journal of Molecular Sciences 24, no. 13 (2023): 10953. http://dx.doi.org/10.3390/ijms241310953.

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In vertebrates, neurotrophins and their receptors play a fundamental role in the central and peripheral nervous systems. Several studies reported that each neurotrophin/receptor signalling pathway can perform various functions during axon development, neuronal growth, and plasticity. Previous investigations in some fish species have identified neurotrophins and their receptors in the spinal cord under physiological conditions and after injuries, highlighting their potential role during regeneration. In our study, for the first time, we used an excellent animal model, the zebrafish (Danio rerio
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20

Sekhar, M. A., Richa Singh, Anuradha Bhat, and Manjari Jain. "Feeding in murky waters: acclimatization and landmarks improve foraging efficiency of zebrafish ( Danio rerio ) in turbid waters." Biology Letters 15, no. 7 (2019): 20190289. http://dx.doi.org/10.1098/rsbl.2019.0289.

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Fish inhabiting human-dominated ecosystems are prone to altered sensory environments in which they must live and function. Increased turbidity is one such change that they must deal with. We tested whether an increase in water turbidity and the presence of visual landmarks (coloured stones) affect the foraging efficiency of wild zebrafish. We also tested the influence of extended exposure to differing turbidity levels on the subsequent foraging efficiency of acclimatized individuals. Feeding latency (time taken to find food) increased significantly with increase in turbidity levels from a mini
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21

Aragona, Marialuisa, Kamel Mhalhel, Lidia Pansera, et al. "Localization of Piezo 1 and Piezo 2 in Lateral Line System and Inner Ear of Zebrafish (Danio rerio)." International Journal of Molecular Sciences 25, no. 17 (2024): 9204. http://dx.doi.org/10.3390/ijms25179204.

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Piezo proteins have been identified as mechanosensitive ion channels involved in mechanotransduction. Several ion channel dysfunctions may be associated with diseases (including deafness and pain); thus, studying them is critical to understand their role in mechanosensitive disorders and to establish new therapeutic strategies. The current study investigated for the first time the expression patterns of Piezo proteins in zebrafish octavolateralis mechanosensory organs. Piezo 1 and 2 were immunoreactive in the sensory epithelia of the lateral line system and the inner ear. Piezo 1 (28.7 ± 1.55
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22

Akanksha Singh and Newton Paul. "Comparative study of chromatophores in fresh water fishes." World Journal of Advanced Research and Reviews 25, no. 3 (2025): 708–11. https://doi.org/10.30574/wjarr.2025.25.3.0760.

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Fish play a vital role in biodiversity. Chromatophores are pigment-bearing cells found in vertebrates, including fish, that allow each species to change its body colour and pattern. Colour changes allow for dynamic camouflage and different means of communication. It is also an excellent example of plasticity, which is required for adaptation and survival in novel environments. Colour change can occur quickly in minutes or gradually over weeks due to various biological mechanisms. Chromatophores are composed of many pigment types that are present in the body and in the eyes in addition to the s
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23

Vargas, R., I. þ. Jóhannesdóttir, B. Sigurgeirsson, H. þorsteinsson, and K. Æ. Karlsson. "The zebrafish brain in research and teaching: a simple in vivo and in vitro model for the study of spontaneous neural activity." Advances in Physiology Education 35, no. 2 (2011): 188–96. http://dx.doi.org/10.1152/advan.00099.2010.

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Recently, the zebrafish ( Danio rerio ) has been established as a key animal model in neuroscience. Behavioral, genetic, and immunohistochemical techniques have been used to describe the connectivity of diverse neural circuits. However, few studies have used zebrafish to understand the function of cerebral structures or to study neural circuits. Information about the techniques used to obtain a workable preparation is not readily available. Here, we describe a complete protocol for obtaining in vitro and in vivo zebrafish brain preparations. In addition, we performed extracellular recordings i
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24

Tongnunui, Sampan, Treerat Sooksawat, Charoonroj Chotwiwatthanakun, Weerayuth Supiwong, Amnuay Wattanakornsiri, and F. W. H. Beamish. "Seasonal Changes in Upper Thermal Tolerances of Freshwater Thai Fishes." Water 15, no. 2 (2023): 350. http://dx.doi.org/10.3390/w15020350.

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Seasonal change inferred to climate change inevitably influences Critical thermal maximum (CTmax) of riverine fishes. In this study, we investigated CTmax as thermal tolerance for four common riverine fishes, i.e., Danio regina, Channa gachua, Rasbora caudimaculata and Mystacoleucus chilopterus, in the Kwae Noi river system in western Thailand. The acute thermal tolerance was lower in the wet season (mean river temperature ∼25 °C) and higher in the dry season (mean river temperature ∼23 °C) with medians of wet season-CTmax for those four fishes of 35.3 ± 0.4, 36.2 ± 0.5, 37.3 ± 0.5 and 37.5 ±
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25

Kavouras, Menelaos, Emmanouil E. Malandrakis, Ewout Blom, et al. "Malpigmentation of Common Sole (Solea solea) during Metamorphosis Is Associated with Differential Synaptic-Related Gene Expression." Animals 11, no. 8 (2021): 2273. http://dx.doi.org/10.3390/ani11082273.

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In farmed flatfish, such as common sole, color disturbances are common. Dyschromia is a general term that includes the color defects on the blind and ocular sides of the fish. The purpose was to examine the difference in gene expression between normal pigmented and juveniles who present ambicoloration. The analysis was carried out with next-generation sequencing techniques and de novo assembly of the transcriptome. Transcripts that showed significant differences (FDR < 0.05) in the expression between the two groups, were related to those of zebrafish (Danio rerio), functionally identified,
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NASRI, Ahmed. "Écotoxicité de l'exposition des larves du poisson zèbre au mélange EE2/A6: Un accent particulier sur la ligne latérale postérieure, PLL." Revue Marocaine des Sciences Agronomiques et Vétérinaires 12, no. 4 (2024): 301–5. https://doi.org/10.5281/zenodo.14582243.

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La ligne latérale postérieure ou PLL est un système mécano-sensoriel présent chez les poissons et les amphibiens, qui permet la détection des mouvements de l’eau dans l’environnement. La stimulation de ce système conduit à une réponse comportementale adaptée, telle que la nage contre le sens du courant, la parade sexuelle, la détection des proies et des prédateurs. Il a disparu chez les organismes terrestres, notamment chez la plupart des tétrapodes, où il a été remplac&e
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Abate, Maria E., Andrew G. Eng, and Les Kaufman. "Alarm cue induces an antipredator morphological defense in juvenile Nicaragua cichlids Hypsophrys nicaraguensis." Current Zoology 56, no. 1 (2010): 36–42. http://dx.doi.org/10.1093/czoolo/56.1.36.

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Abstract Olfactory cues that indicate predation risk elicit a number of defensive behaviors in fishes, but whether they are sufficient to also induce morphological defenses has received little attention. Cichlids are characterized by a high level of morphological plasticity during development, and the few species that have been tested do exhibit defensive behaviors when exposed to alarm cues released from the damaged skin of conspecifics. We utilized young juvenile Nicaragua cichlids Hypsophrys nicaraguensis to test if the perception of predation risk from alarm cue (conspecific skin extract)
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Hinojosa, Gabriella, Mia Ruiz, Kassandra Garcia, and Robert Dearth. "RF22 | PMON06 The Contraceptive Synthetic-Progesterone Levonorgestrel (LNG) Significantly Accelerates Fetal Hypothalamic Neuronal Development (Neuroendogenesis) in the Zebrafish (Danio rerio)." Journal of the Endocrine Society 6, Supplement_1 (2022): A446. http://dx.doi.org/10.1210/jendso/bvac150.928.

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Abstract The fetal brain has a known vulnerability to exogenous influences due to its plasticity and high volume of replicating and differentiating cells. It is particularly susceptible to a group of environmental molecules classified as endocrine disrupting chemicals (EDCs). Previous vertebrate studies have provided supportive evidence that steroid mimicking EDCs might stimulate hypothalamic progenitor cell differentiation to neurons (neuroendogenesis). Changing the normal timing of neuroendogenesis could play a role in establishing an alternative developmental timeline leading to disruptions
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29

Sourisse, Jade M., Julie L. Semmelhack, and Celia Schunter. "Parental thermal conditions affect the brain activity response to alarm cue in larval zebrafish." PeerJ 12 (October 10, 2024): e18241. http://dx.doi.org/10.7717/peerj.18241.

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Temperature is a crucial factor affecting the physiology of ectothermic animals, but exposure to elevated temperature during specific life stages and across generations may confer fish resilience through phenotypic plasticity. In this study, we investigate the effects of developmental and parental temperature on brain activity response to an olfactory cue in the larval zebrafish, Danio rerio. We exposed parents during reproduction and their offspring during development to control (28 °C) or elevated temperature (30 °C) and observed the response of the larval telencephalon to an alarm cue using
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30

Sumon, Md Afsar Ahmed, Mohammad Habibur Rahman Molla, Israa J. Hakeem, et al. "Epigenetics and Probiotics Application toward the Modulation of Fish Reproductive Performance." Fishes 7, no. 4 (2022): 189. http://dx.doi.org/10.3390/fishes7040189.

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Fish represent an excellent source of animal protein as well as a biomedical research model as a result of their evolutionary relatedness and similarity with the human genome. Commercial and ornamental fish culture has achieved popularity, but reproductive dysfunctions act as a limiting factor for quality fry production, interfering with the sustainability of the aquaculture industry. Fish reproduction is crucial for any species’ existence, and reproductive performance can potentially be improved through applications of epigenetics and probiotics. Epigenetics is a highly sensitive molecular ap
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31

Navarro-Guillén, Carmen, Gabriella do Vale Pereira, André Lopes, Rita Colen, and Sofia Engrola. "Egg nutritional modulation with amino acids improved performance in zebrafish larvae." PLOS ONE 16, no. 4 (2021): e0248356. http://dx.doi.org/10.1371/journal.pone.0248356.

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New and more efficient methods to sustainably intensify Aquaculture production are essential to attain the seafood demand for direct human consumption in the near future. Nutrition has been identified as one strategy of early exposure that might affect animal early development and later phenotype. This strategy may have positive consequences in the modulation of fish digestive physiology, which will correlate with higher performance outputs. Thus, improving fish digestive efficiency will lead to higher productivity and lower biogenic emission from aquaculture facilities, minimising the impact
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32

Pelster, B., A. M. Sänger, M. Siegele, and T. Schwerte. "Influence of swim training on cardiac activity, tissue capillarization, and mitochondrial density in muscle tissue of zebrafish larvae." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 285, no. 2 (2003): R339—R347. http://dx.doi.org/10.1152/ajpregu.00110.2003.

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Larval zebrafish ( Danio rerio) of two different age classes (“swim-up” larvae, 9 days old; “free-swimming” larvae, 21 days old) were exposed to either an endurance/continuous training or interval training. Control animals were kept in stagnant water. A comparison of cardiac activity of trained (either endurance or interval) and untrained animals at the end of the training regime revealed no differences in heart rate, end-diastolic and end-systolic ventricular volume, and cardiac output. Training also had no influence on the concentration of erythrocytes in the blood. Thus, at the level of tot
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Pessoa, Antônia De Castro Côrtes, Francisco Pessoa Machado, Cláudio Ângelo da Silva Neto, José Antonio Beltrão Sabadia, Cynthia Romariz Duarte, and César Ulisses Vieira Veríssimo. "Aproveitamento dos rejeitos das indústrias de calcinação de calcário na porção setentrional do estado do Ceará com foco na reparação de dano ambiental." Revista Brasileira de Geografia Física 13, no. 3 (2020): 1309. http://dx.doi.org/10.26848/rbgf.v13.3.p1309-1323.

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Os resíduos gerados no processo de calcinação dos calcários formam pilhas que se constituem em fontes de degradação do meio ambiente e obstáculos ao bom andamento das atividades das unidades produtoras. O aproveitamento desses rejeitos pode gerar benefícios ao meio ambiente, bem como melhorias ao trabalho dos operários, além de ser mais uma fonte de renda para as indústrias de calcinação locais. Este estudo foi desenvolvido no sentido do aproveitamento racional e econômico desses materiais residuais na pavimentação de estradas e na construção de obras de aterro que exijam solo estabilizado e,
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van der Zalm, Amber Perenna, Mark P. Dings, Reimer Janssen, et al. "Abstract 2616: Stemness factors nanog and oct4 contribute to epithelial-to-mesenchymal transition and are predictive for outcome in esophageal adenocarcinoma." Cancer Research 82, no. 12_Supplement (2022): 2616. http://dx.doi.org/10.1158/1538-7445.am2022-2616.

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Abstract Background and Aims: The incidence of esophageal adenocarcinoma (EAC) has increased six-fold in Western countries over the last decades, and 5-year survival rates remain low at 5-20%. While multimodality treatment strategies for curative treatment of esophageal cancer, including the CROSS regimen (chemoradiotherapy followed by surgery) have increased median overall survival, the majority of patients develop recurrences after several months. Epithelial to mesenchymal transition (EMT) has been recently shown by our group to be one of the major underlying mechanisms of resistance to ther
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35

Seebacher, Frank, and Alec I. M. Simmonds. "Histone deacetylase activity mediates thermal plasticity in zebrafish (Danio rerio)." Scientific Reports 9, no. 1 (2019). http://dx.doi.org/10.1038/s41598-019-44726-x.

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36

Lewis, Victor M., Lauren M. Saunders, Tracy A. Larson, et al. "Fate plasticity and reprogramming in genetically distinct populations of Danio leucophores." Proceedings of the National Academy of Sciences, May 28, 2019, 201901021. http://dx.doi.org/10.1073/pnas.1901021116.

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Understanding genetic and cellular bases of adult form remains a fundamental goal at the intersection of developmental and evolutionary biology. The skin pigment cells of vertebrates, derived from embryonic neural crest, are a useful system for elucidating mechanisms of fate specification, pattern formation, and how particular phenotypes impact organismal behavior and ecology. In a survey of Danio fishes, including the zebrafish Danio rerio, we identified two populations of white pigment cells—leucophores—one of which arises by transdifferentiation of adult melanophores and another of which de
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Huang, Delai, Victor M. Lewis, Tarah N. Foster, Matthew B. Toomey, Joseph C. Corbo, and David M. Parichy. "Development and genetics of red coloration in the zebrafish relative Danio albolineatus." eLife 10 (August 26, 2021). http://dx.doi.org/10.7554/elife.70253.

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Animal pigment patterns play important roles in behavior and, in many species, red coloration serves as an honest signal of individual quality in mate choice. Among Danio fishes, some species develop erythrophores, pigment cells that contain red ketocarotenoids, whereas other species, like zebrafish (D. rerio) only have yellow xanthophores. Here, we use pearl danio (D. albolineatus) to assess the developmental origin of erythrophores and their mechanisms of differentiation. We show that erythrophores in the fin of D. albolineatus share a common progenitor with xanthophores and maintain plastic
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38

Massey, Melanie D., M. Kate Fredericks, David Malloy, Suchinta Arif, and Jeffrey A. Hutchings. "Differential reproductive plasticity under thermal variability in a freshwater fish ( Danio rerio )." Proceedings of the Royal Society B: Biological Sciences 289, no. 1982 (2022). http://dx.doi.org/10.1098/rspb.2022.0751.

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Human-driven increases in global mean temperatures are associated with concomitant increases in thermal variability. Yet, few studies have explored the impacts of thermal variability on fitness-related traits, limiting our ability to predict how organisms will respond to dynamic thermal changes. Among the myriad organismal responses to thermal variability, one of the most proximate to fitness—and, thus, a population's ability to persist—is reproduction. Here, we examine how a model freshwater fish ( Danio rerio ) responds to diel thermal fluctuations that span the species's viable developmenta
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Imai, Ana Paula, Thiago de Oliveira Abeche, and Roberto Dalledone Machado. "Damage and plasticity evolution of reinforced concrete beams using laminated Euler-Bernoulli finite elements." Revista IBRACON de Estruturas e Materiais 16, no. 5 (2023). http://dx.doi.org/10.1590/s1983-41952023000500002.

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abstract: This paper analyses the behaviour of reinforced concrete beams subjected to progressive loads. Although this topic is addressed in recent works through tri-dimensional finite elements, the present study adopts a simpler alternative, using Euler-Bernoulli’s beam finite element. The evolution of the generalized cracking is addressed by Damage Mechanics theory, and the nonlinear constitutive models of concrete and steel are considered, including plasticity and post-peak ‘. The laminated approach permits not only to ascertain the damage evolution but, in practical aspects, makes easy to
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Stevanović, Marija, Niki Tagkalidou, Cristiana Roberta Multisanti, et al. "Zebra_K, a kinematic analysis automated platform for assessing sensitivity, habituation and prepulse inhibition of the acoustic startle response in adult zebrafish." Science of The Total Environment 958, no. 178028 (2025). https://doi.org/10.1016/j.scitotenv.2024.178028.

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The acoustic startle response (ASR) is leaded by a sudden and intense acoustic stimulus. ASR has several forms of plasticity, including habituation and sensorimotor gating. Although ASR and its plasticity have been intensively studied in zebrafish (<em>Danio rerio</em>) larvae, information in adult zebrafish is still very scarce. In this manuscript we present Zebra_K, a new automated high-content kinematic analysis platform for assessing ASR, its habituation and prepulse inhibition (PPI), a quantitative measure of sensorimotor gating, in adult zebrafish. The analysis of the kinematic parameter
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Martini, Arianna, Ann Huysseune, Paul Eckhard Witten, and Clara Boglione. "Plasticity of the skeleton and skeletal deformities in zebrafish ( Danio rerio ) linked to rearing density." Journal of Fish Biology, February 19, 2020. http://dx.doi.org/10.1111/jfb.14272.

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Hosseini, Shahrbanou, Ngoc-Thuy Ha, Henner Simianer, et al. "Genetic mechanism underlying sexual plasticity and its association with colour patterning in zebrafish (Danio rerio)." BMC Genomics 20, no. 1 (2019). http://dx.doi.org/10.1186/s12864-019-5722-1.

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Heagy, Faith K., Katie N. Clements, Carrie L. Adams, Elena Blain, and Fadi A. Issa. "Socially induced plasticity of the posterior tuberculum and motor behavior in zebrafish (Danio rerio)." Journal of Experimental Biology, October 18, 2024. http://dx.doi.org/10.1242/jeb.248148.

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Social dominance is prevalent throughout the animal kingdom. It facilitates the stabilization of social relationships and allows animals to divide resources according to social rank. Zebrafish form stable dominance relationships that consist of dominants and subordinates. Although social-status-dependent differences in behavior must arise due to neural plasticity, mechanisms of how neural circuits are reconfigured to cope with social dominance are poorly described. Here, we describe how the posterior tuberculum nucleus (PT), which integrates sensory social information to modulate spinal motor
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Loughland, Isabella, Alexander Little, and Frank Seebacher. "DNA methyltransferase 3a mediates developmental thermal plasticity." BMC Biology 19, no. 1 (2021). http://dx.doi.org/10.1186/s12915-020-00942-w.

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Abstract Background Thermal plasticity is pivotal for evolution in changing climates and in mediating resilience to its potentially negative effects. The efficacy to respond to environmental change depends on underlying mechanisms. DNA methylation induced by DNA methyltransferase 3 enzymes in the germline or during early embryonic development may be correlated with responses to environmental change. This developmental plasticity can interact with reversible acclimation within adult organisms, which would increase the speed of response and could alleviate potential mismatches between parental o
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Dunlap, Kent D., Magda C. Teles, and Rui F. Oliveira. "Social stimuli increase activity of adult-born cells in the telencephalon of zebrafish (Danio rerio)." Journal of Experimental Biology 224, no. 16 (2021). http://dx.doi.org/10.1242/jeb.242253.

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ABSTRACT Fish have particularly high levels of adult neurogenesis, and this high neurogenic capacity may contribute to behavioural plasticity. While it is known that adult-born cells can differentiate into neurons and incorporate into neural circuits, it is unclear whether they are responsive to external stimuli and are thereby capable of contributing to behavioural change. We tested whether cells born in the telencephalon of adult zebrafish are activated by social stimuli. We marked cell birth with BrdU and, 40 days later, exposed fish to brief (15 min) visual social stimuli and assayed cellu
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Grigg, A. G., T. M. Lowi‐Merri, J. A. Hutchings, and M. D. Massey. "Thermal variability induces sex‐specific morphometric changes in zebrafish (Danio rerio)." Journal of Fish Biology, September 7, 2023. http://dx.doi.org/10.1111/jfb.15551.

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AbstractIn nature, organisms are exposed to variable environmental conditions that impact their performance and fitness. Despite the ubiquity of environmental variability, substantial knowledge gaps in our understanding of organismal responses to non‐constant thermal regimes remain. In the present study, using zebrafish (Danio rerio) as a model organism, we applied geometric morphometric methods to examine how challenging but ecologically realistic diel thermal fluctuations experienced during different life stages influence adult body shape, size and condition. Zebrafish were exposed to either
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Massey, Melanie D., and Anne C. Dalziel. "Parental early life environments drive transgenerational plasticity of offspring metabolism in a freshwater fish ( Danio rerio )." Biology Letters 19, no. 10 (2023). http://dx.doi.org/10.1098/rsbl.2023.0266.

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Parental experiences can lead to changes in offspring phenotypes through transgenerational plasticity (TGP). TGP is expected to play a role in improving the responses of offspring to changes in climate, but little is known about how the early lives of parents influence offspring TGP. Here, we use a model organism, zebrafish ( Danio rerio ), to contrast the effects of early and later life parental thermal environments on offspring routine metabolism. To accomplish this, we exposed both parents to either constant optimal (27°C) or environmentally realistic diel fluctuating (22–32°C) temperatures
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Berio, Fidji, Camille Morerod, Xuewei Qi, and Valentina Di Santo. "Ontogenetic Plasticity in Shoaling Behavior in a Forage Fish under Warming." Integrative And Comparative Biology, May 27, 2023. http://dx.doi.org/10.1093/icb/icad043.

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Abstract Shoaling behavior is known to increase survival rates during attacks from predators, minimize foraging time, favor mating, and potentially increase locomotor efficiency. The onset of shoaling typically occurs during the larval phase but it is unclear how it may improve across ontogenetic stages in forage fishes. Warming is known to increase metabolic rates during locomotion in solitary fish, and shoaling species may adjust their collective behavior to offset the elevated costs of swimming at higher temperatures. In this study, we quantified the effects of warming on shoaling performan
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Pettersen, Amanda K., Neil B. Metcalfe, and Frank Seebacher. "Intergenerational plasticity aligns with temperature-dependent selection on offspring metabolic rates." Philosophical Transactions of the Royal Society B: Biological Sciences 379, no. 1896 (2024). http://dx.doi.org/10.1098/rstb.2022.0496.

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Metabolic rates are linked to key life-history traits that are thought to set the pace of life and affect fitness, yet the role that parents may have in shaping the metabolism of their offspring to enhance survival remains unclear. Here, we investigated the effect of temperature (24°C or 30°C) and feeding frequency experienced by parent zebrafish ( Danio rerio ) on offspring phenotypes and early survival at different developmental temperatures (24°C or 30°C). We found that embryo size was larger, but survival lower, in offspring from the parental low food treatment. Parents exposed to the warm
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Clements, Katie N., Sungwoo Ahn, Choongseok Park, et al. "Socially mediated shift in neural circuits activation regulated by synergistic neuromodulatory signaling." eneuro, November 1, 2023, ENEURO.0311–23.2023. http://dx.doi.org/10.1523/eneuro.0311-23.2023.

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Animals exhibit context-dependent behavioral decisions that are mediated by specific motor circuits. In social species these decisions are often influenced by social status. Although social status-dependent neural plasticity of motor circuits has been investigated in vertebrates, little is known of how cellular plasticity translates into differences in motor activity. Here, we used zebrafish (Danio rerio) as a model organism to examine how social dominance influences the activation of swimming and the Mauthner mediated startle escape behaviors. We show that the status-dependent shift in behavi
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