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1

Avril, Marion, Bridget R. Kulasekara, Severin O. Gose, et al. "Evidence for Globally Shared, Cross-Reacting Polymorphic Epitopes in the Pregnancy-Associated Malaria Vaccine Candidate VAR2CSA." Infection and Immunity 76, no. 4 (2008): 1791–800. http://dx.doi.org/10.1128/iai.01470-07.

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ABSTRACT Pregnancy-associated malaria (PAM) is characterized by the placental sequestration of Plasmodium falciparum-infected erythrocytes (IEs) with the ability to bind to chondroitin sulfate A (CSA). VAR2CSA is a leading candidate for a pregnancy malaria vaccine, but its large size (∼350 kDa) and extensive polymorphism may pose a challenge to vaccine development. In this study, rabbits were immunized with individual VAR2CSA Duffy binding-like (DBL) domains expressed in Pichia pastoris or var2csa plasmid DNA and sera were screened on different CSA-binding parasite lines. Rabbit antibodies to
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KAMALA, ADAK, BASU ANKITA, DAS TRINA, GHOSH SUMANA, and CHATTERJEE AMITAVA. "ANTIOXIDANT PROPERTY OF LEMON-TEA – ROLE OF INFUSION TIME AND LEMON JUICE VOLUME." Journal of Advances in Food Science & Technology 4, no. 1 (2016): 1–10. https://doi.org/10.5281/zenodo.1411635.

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The study encompasses the effect of fresh lemon juice in varied portions (1, 2 & 3 mL) to tea (green & black) after infusions for 5, 10 & 15 min in uncontrolled environment (household tea making process) and estimated some secondary metabolites and antioxidant potential of Darjeeling Green-Lemon Tea (DGLT) and Darjeeling Black-Lemon Tea (DBLT). Lemon juice additions resulted in lessening the concentrations of polyphenols and especially, the tannins but the rate of decrement lowered with higher quantity of juice additions leading to the fact that lemon exerts its protective role to
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Saveria, Tracy, Andrew V. Oleinikov, Kathryn Wiliamson, et al. "Antibodies to Escherichia coli-Expressed C-Terminal Domains of Plasmodium falciparum Variant Surface Antigen 2-Chondroitin Sulfate A (VAR2CSA) Inhibit Binding of CSA-Adherent Parasites to Placental Tissue." Infection and Immunity 81, no. 4 (2013): 1031–39. http://dx.doi.org/10.1128/iai.00978-12.

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ABSTRACTPlacental malaria (PM) is characterized by infected erythrocytes (IEs) that selectively bind to chondroitin sulfate A (CSA) and sequester in placental tissue. Variant surface antigen 2-CSA (VAR2CSA), aPlasmodium falciparumerythrocyte membrane protein 1 (PfEMP1) protein family member, is expressed on the surface of placental IEs and mediates adherence to CSA on the surface of syncytiotrophoblasts. This transmembrane protein contains 6 Duffy binding-like (DBL) domains which might contribute to the specific adhesive properties of IEs. Here, we use laboratory isolate 3D7 VAR2CSA DBL domain
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4

Hutchinson, J., and M. Lacki. "Selection of day roosts by red bats in mixed mesophytic forests." Journal of Wildlife Management 64, no. 1 (2000): 87–94. https://doi.org/10.2307/3802977.

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Limited information exists on the choice of day roosts by red bats (Lasiurus borealis) in mature deciduous forests. We radiotracked 10 adult female and 4 adult male red hats as they used 44 day roosts in nived mesophytic forests in castern Kentucky during May through August 1996-97. On average (x ± SE). bats roosted 16.5 ± 0.3 to above ground in the outer foliage of the canopy of 13 different species of hardwood trees: no conifer or snag was used as a day roost. Roost trees were dominant and codominant trees averaging 10.5 1.9 cur dblt. Most roost trees 77.3% were on ridge tops of upland fores
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5

Avril, Marion, Megan M. Cartwright, Marianne J. Hathaway, et al. "Immunization with VAR2CSA-DBL5 Recombinant Protein Elicits Broadly Cross-Reactive Antibodies to Placental Plasmodium falciparum-Infected Erythrocytes." Infection and Immunity 78, no. 5 (2010): 2248–56. http://dx.doi.org/10.1128/iai.00410-09.

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ABSTRACTPregnancy-associated malaria is a severe clinical syndrome associated with the sequestration ofPlasmodium falciparum-infected erythrocytes in the placenta. Placental binding is mediated by VAR2CSA, a member of the large and diverseP. falciparumerythrocyte membrane 1 (PfEMP1) protein family. To better understand if conserved regions in VAR2CSA can be targeted by antibodies, we immunized rabbits with VAR2CSA-DBL1 and -DBL5 recombinant proteins produced inPichia pastorisand developed a panel of seven chondroitin sulfate A (CSA)-binding parasites from diverse geographic origins. Overall, n
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Fried, Michal, Marion Avril, Richa Chaturvedi, et al. "Multilaboratory Approach to Preclinical Evaluation of Vaccine Immunogens for Placental Malaria." Infection and Immunity 81, no. 2 (2012): 487–95. http://dx.doi.org/10.1128/iai.01106-12.

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ABSTRACTPregnancy malaria is caused byPlasmodium falciparum-infected erythrocytes that adhere to the placental receptor chondroitin sulfate A (CSA) and sequester in the placenta; women become resistant to pregnancy malaria as they acquire antiadhesion antibodies that target surface proteins of placental parasites. VAR2CSA, a member of theP. falciparumEMP1 variant surface antigen family, is the leading candidate for a pregnancy malaria vaccine. Because VAR2CSA is a high-molecular-weight protein, a vaccine based on the full-length protein may not be feasible. An alternative approach has been to
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7

Cui, Hong Xia. "Effect of Crude Polysaccharides from Discorea bulbifera L. on the Liver in the Mice Bearing U14 Cervical Carcinoma." Advanced Materials Research 989-994 (July 2014): 1044–47. http://dx.doi.org/10.4028/www.scientific.net/amr.989-994.1044.

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To explore the effect of crude polysaccharides of Dioscorea bulbifera L. (DBLP) on liver organs in mice bearing cervical cancer, the effects of DBLP on the liver weight in vivo, sections of liver were examined. Glutamate pyruvate transaminase (GPT) and Glutamic oxalo acetic Transaminase (GOT) activites of blood serum in tumor-bearing mice were detected by the colorimetric method. Superoxide dismutase (SOD) and Glutathione reductase (GR) of hepatic tissues were also determined by means of colorimetric method. Our results showed that the liver index, GPT and GOT activities of blood serum, SOD an
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8

Avril, Marion, Megan M. Cartwright, Marianne J. Hathaway, and Joseph D. Smith. "Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins." Malaria Journal 10, no. 1 (2011): 36. http://dx.doi.org/10.1186/1475-2875-10-36.

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9

Coelho, Igor M., Vitor N. Coelho, Rodolfo P. Araujo, Wang Yong Qiang, and Brett D. Rhodes. "Challenges of PBFT-Inspired Consensus for Blockchain and Enhancements over Neo dBFT." Future Internet 12, no. 8 (2020): 129. http://dx.doi.org/10.3390/fi12080129.

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Consensus mechanisms are a core feature for handling negotiation and agreements. Blockchain technology has seen the introduction of different sorts of consensus mechanism, ranging from tasks of heavy computation to the subtle mathematical proofs of Byzantine agreements. This paper presents the pioneer Delegated Byzantine Fault Tolerance (dBFT) protocol of Neo Blockchain, which was inspired by the Practical Byzantine Fault Tolerance (PBFT). Besides introducing its history, this study describes proofs and didactic examples, as well as novel design and extensions for Neo dBFT with multiple block
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10

Evoy, Richard, Laurel Kincl, Diana Rohlman, et al. "Impact of acute temperature and air pollution exposures on adult lung function: A panel study of asthmatics." PLOS ONE 17, no. 6 (2022): e0270412. http://dx.doi.org/10.1371/journal.pone.0270412.

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Background Individuals with respiratory conditions, such as asthma, are particularly susceptible to adverse health effects associated with higher levels of ambient air pollution and temperature. This study evaluates whether hourly levels of fine particulate matter (PM2.5) and dry bulb globe temperature (DBGT) are associated with the lung function of adult participants with asthma. Methods and findings Global positioning system (GPS) location, respiratory function (measured as forced expiratory volume at 1 second (FEV1)), and self-reports of asthma medication usage and symptoms were collected a
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van Iersel, Patricia A. M., Annechien M. Algra, Saskia C. M. Bakker, Arnold J. H. Jonker, and Mijna Hadders-Algra. "Limitations in the Activity of Mobility at Age 6 Years After Difficult Birth at Term: Prospective Cohort Study." Physical Therapy 96, no. 8 (2016): 1225–33. http://dx.doi.org/10.2522/ptj.20150201.

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Abstract Background A difficult birth at term (DBAT) may manifest as fetal acidosis and low Apgar scores and is often referred to as “perinatal asphyxia,” especially when infants show signs of neonatal encephalopathy (NE). In contrast to DBAT resulting in moderate-to-severe NE, which is associated with neurodevelopmental disorders, little is known about the prognosis of less severe forms of DBAT, with or without NE. Objective The purpose of this study was to evaluate the International Classification of Functioning, Disability and Health, Children & Youth Version activity “mobility” and oth
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Taiwo, Rasheed Ayinde, Yeongil Son, Joonghan Shin, and Yusuff Adeyemi Salawu. "Enhanced Activation in Phosphorous-Doped Silicon via Dual-Beam Laser Annealing." Materials 17, no. 17 (2024): 4316. http://dx.doi.org/10.3390/ma17174316.

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In this study, we conduct a comparative analysis of single-beam laser annealing (SBLA) and dual-beam laser annealing (DBLA) techniques for semiconductor manufacturing. In the DBLA approach, two laser beams were precisely aligned to simultaneously heat a phosphorus-doped silicon (Si) wafer. The main objective was to investigate the impact of the two annealing techniques on the electrical properties, crystalline structure, and diffusion profile of the treated phosphorus-doped Si at equivalent laser powers. Both SBLA and DBLA improved the electrical properties of the phosphorus-doped Si, evidence
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13

Berthold, Daniel P., Lukas N. Muench, Antonio Cusano, et al. "Clinical and Functional Outcomes After Operative and Nonoperative Treatment of Distal Biceps Brachii Tendon Ruptures in a Consecutive Case Series." Orthopaedic Journal of Sports Medicine 9, no. 6 (2021): 232596712098484. http://dx.doi.org/10.1177/2325967120984841.

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Background: Patients with ruptures of the distal biceps brachii tendon (DBBT) have traditionally been treated via surgical repair, despite limited patient data on nonoperative management. Purpose/Hypothesis: To determine the clinical and functional outcomes for patients with partial and complete DBBT injuries treated nonoperatively or surgically through an anatomic single-incision technique. We hypothesized that there would be no difference in outcomes in patients treated with nonoperative or operative management. Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective chart
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14

Cui, Hong Xia. "Antitumor Activity and Possible Mechanism of Crude Polysaccharides from Discorea bulbifera L. on the Mice Bearing U14 Cervical Carcinoma." Advanced Materials Research 560-561 (August 2012): 374–79. http://dx.doi.org/10.4028/www.scientific.net/amr.560-561.374.

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To explore the antitumor activity of crude polysaccharides of Dioscorea bulbifera L. (DBLP) and its possible mechanism, the effects of DBLP on the tumor growth in vivo, thymus and spleen weight were examined. Apoptosis of thymus, spleen and tumor tissue in tumor-bearing mice was detected by the flow cytometry. The number of CD4+ and CD8+ T-lymphocyte subsets of peripheral blood was also determined by means of FACScan flow cytometer. Our results showed that U14 cervical carcinoma growth could be inhibited, thymus weight be increased, apoptosis of thymus and spleen be decreased, and apoptosis of
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Broni-Bediako, Eric, Daniel Ocran, and Randy Tenkorang Osafo. "Exploring the Performance of Dry Bamboo Leaves Powder from Bambusa Heterostachya as Additive in Water-Based Mud." International Journal of Emerging Science and Engineering 12, no. 9 (2024): 1–7. http://dx.doi.org/10.35940/ijese.f4529.12090824.

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In the evolving landscape of petroleum drilling, the quest for eco-friendly alternatives to traditional mud additives is paramount. This study explored the performance of Dry Bamboo Leaves Powder (DBLP) from Bambusa heterostachya as an additive in water-based mud. Dry Bamboo Leaves were obtained, crushed, and then sieved to 106-micron size. Mud properties, including mud weight, plastic viscosity, yield point, gel strength, mud cake thickness and filtrate volume were examined under fresh conditions by integrating different concentrations of DBLP (3.5 g, 7.0 g, 10.5 g, and 14 g). The laboratory
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Eric, Broni-Bediako. "Exploring the Performance of Dry Bamboo Leaves Powder from Bambusa Heterostachya as Additive in Water-Based Mud." International Journal of Emerging Science and Engineering (IJESE) 12, no. 9 (2024): 1–7. https://doi.org/10.35940/ijese.F4529.12090824.

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<strong>Abstract:</strong> In the evolving landscape of petroleum drilling, the quest for eco-friendly alternatives to traditional mud additives is paramount. This study explored the performance of Dry Bamboo Leaves Powder (DBLP) from Bambusa heterostachya as an additive in water-based mud. Dry Bamboo Leaves were obtained, crushed, and then sieved to 106-micron size. Mud properties, including mud weight, plastic viscosity, yield point, gel strength, mud cake thickness and filtrate volume were examined under fresh conditions by integrating different concentrations of DBLP (3.5 g, 7.0 g, 10.5 g,
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Cui, Meng-Di, Zi-Hao Pan та Li-Qun Pan. "Danggui Buxue Extract-Loaded Liposomes in Thermosensitive Gel Enhance In Vivo Dermal Wound Healing via Activation of the VEGF/PI3K/Akt and TGF-β/Smads Signaling Pathway". Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–13. http://dx.doi.org/10.1155/2017/8407249.

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Danggui Buxue extract-loaded liposomes in thermosensitive gel (DBLTG) are a sustained-release local drug delivery system derived from Danggui Buxue decoction, a well-known Chinese herb formula with wound healing potential. In the present study, we investigated the therapeutic effects of DBLTG on dorsal full-thickness excisional wounds in rats by measuring the percentage of wound contraction and hydroxyproline content, as well as conducting histological observations and immunohistochemical analysis. We also assessed involvement of the vascular endothelial growth factor (VEGF)/phosphatidylinosit
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Setyami, Inung, and Irma Satriani. "PEREMPUAN, CINTA, DAN RELIGI DALAM DI BAWAH LINDUNGAN KA’BAH KARYA HAMKA: KEBERAKSARAAN DAN KELISANAN." SEMIOTIKA: Jurnal Ilmu Sastra dan Linguistik 24, no. 2 (2023): 253. http://dx.doi.org/10.19184/semiotika.v24i2.34300.

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Film is the result of the culture of high-tech society that is presented through audio-visuals. many blockbusters whose screenplays are adaptations or inspirations from literary works. One example of the many literary works that have been multimediaized is the novel Di Bawah Lindungan Ka’ bah (DBLK). This study aims to describe the representation of women, love, and religion in Hamka's novel DBLK. in terms of literacy and orality both. The research data source is the novel DBLK by Hamka. The DBLK novel was first published by the publisher Bulan Bintang in 1938. The type of research is descript
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Börlin, Niclas, and Pierre Grussenmeyer. "EXTERNAL VERIFICATION OF THE BUNDLE ADJUSTMENT IN PHOTOGRAMMETRIC SOFTWARE USING THE DAMPED BUNDLE ADJUSTMENT TOOLBOX." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B5 (June 15, 2016): 7–14. http://dx.doi.org/10.5194/isprs-archives-xli-b5-7-2016.

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The aim of this paper is to investigate whether the Matlab-based Damped Bundle Adjustment Toolbox (DBAT) can be used to provide independent verification of the BA computation of two popular software—PhotoModeler (PM) and PhotoScan (PS). &lt;br&gt;&lt;br&gt; For frame camera data sets with lens distortion, DBAT is able to reprocess and replicate subsets of PM results with high accuracy. For lens-distortion-free data sets, DBAT can furthermore provide comparative results between PM and PS. Data sets for the discussed projects are available from the authors. &lt;br&gt;&lt;br&gt; The use of an ext
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Börlin, Niclas, and Pierre Grussenmeyer. "EXTERNAL VERIFICATION OF THE BUNDLE ADJUSTMENT IN PHOTOGRAMMETRIC SOFTWARE USING THE DAMPED BUNDLE ADJUSTMENT TOOLBOX." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B5 (June 15, 2016): 7–14. http://dx.doi.org/10.5194/isprsarchives-xli-b5-7-2016.

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The aim of this paper is to investigate whether the Matlab-based Damped Bundle Adjustment Toolbox (DBAT) can be used to provide independent verification of the BA computation of two popular software—PhotoModeler (PM) and PhotoScan (PS). &amp;lt;br&amp;gt;&amp;lt;br&amp;gt; For frame camera data sets with lens distortion, DBAT is able to reprocess and replicate subsets of PM results with high accuracy. For lens-distortion-free data sets, DBAT can furthermore provide comparative results between PM and PS. Data sets for the discussed projects are available from the authors. &amp;lt;br&amp;gt;&amp
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Ullah, Fahim, Kamran Hasrat, Sami Iqbal, and Shuang Wang. "Design and Development of D-A-D Organic Material for Solution-Processed Organic/Si Hybrid Solar Cells with 17.5% Power Conversion Efficiency." Molecules 29, no. 22 (2024): 5369. http://dx.doi.org/10.3390/molecules29225369.

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Organic/silicon hybrid solar cells have attracted much interest due to their cheap fabrication process and simple device structure. A category of organic substances, Dibenzothiophene–Spirobifluorene–Dithiophene (DBBT-mTPA-DBT), comprises dibenzo [d,b] thiophene and 3-(3-methoxyphenyl)-6-(4-methoxyphenyl)-9H-Carbazole, which function as electron donors. In contrast, methanone is an electron acceptor, with an ∆Est of 3.19 eV. This work focused on hybrid solar cells based on the guest–host phenomena of DBBT-mTPA-DBT and CBP. Using a Si/poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate) (PED
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Tonkin-Hill, Gerry, Shazia Ruybal-Pesántez, Kathryn E. Tiedje, et al. "Evolutionary analyses of the major variant surface antigen-encoding genes reveal population structure of Plasmodium falciparum within and between continents." PLOS Genetics 17, no. 2 (2021): e1009269. http://dx.doi.org/10.1371/journal.pgen.1009269.

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Malaria remains a major public health problem in many countries. Unlike influenza and HIV, where diversity in immunodominant surface antigens is understood geographically to inform disease surveillance, relatively little is known about the global population structure of PfEMP1, the major variant surface antigen of the malaria parasite Plasmodium falciparum. The complexity of the var multigene family that encodes PfEMP1 and that diversifies by recombination, has so far precluded its use in malaria surveillance. Recent studies have demonstrated that cost-effective deep sequencing of the region o
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Tan, Mun Hua, Kathryn E. Tiedje, Qian Feng та ін. "A paradoxical population structure of var DBLα types in Africa". PLOS Pathogens 21, № 2 (2025): e1012813. https://doi.org/10.1371/journal.ppat.1012813.

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The var multigene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), central to host-parasite interactions. Genome structure studies have identified three major groups of var genes by specific upstream sequences (upsA, B, or C). Var with these ups groups have different chromosomal locations, transcriptional directions, and associations with disease severity. Here we explore temporal and spatial diversity of a region of var genes encoding the DBLα domain of PfEMP1 in Africa. By applying a novel ups classification algorithm (cUps) to publicly-available DBLα sequence da
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Misova, Ivana, Alexandra Pitelova, Jaroslav Budis, et al. "Repression of a large number of genes requires interplay between homologous recombination and HIRA." Nucleic Acids Research 49, no. 4 (2021): 1914–34. http://dx.doi.org/10.1093/nar/gkab027.

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AbstractDuring homologous recombination, Dbl2 protein is required for localisation of Fbh1, an F-box helicase that efficiently dismantles Rad51–DNA filaments. RNA-seq analysis of dbl2Δ transcriptome showed that the dbl2 deletion results in upregulation of more than 500 loci in Schizosaccharomyces pombe. Compared with the loci with no change in expression, the misregulated loci in dbl2Δ are closer to long terminal and long tandem repeats. Furthermore, the misregulated loci overlap with antisense transcripts, retrotransposons, meiotic genes and genes located in subtelomeric regions. A comparison
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Oviedo Donayre, Pilar. "Validación del Nuevo Ensayo Tiempo de Bothrops atrox diluido (dBat) para la Detección de Anticoagulante Lúpico." Anales de la Facultad de Medicina 61, no. 1 (2014): 7. http://dx.doi.org/10.15381/anales.v61i1.4244.

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OBJETIVO: Validar un nuevo ensayo para detección de anticoagulante lúpico, el cual emplea el veneno crudo diluido del Bothrops atrox (dBat), comparado con cuatro ensayos de coagulación fosfolípido- dependientes: dRVVT, TTPa, TTI y TNP MATERIAL Y MÉTODOS: Se evaluó 70 muestras de plasma citratado de pacientes con diagnóstico clínico de LES, síndrome antifosfolípido primario (SAFP), trombosis/embolia y sospecha de trombosis, hospitalizados en el Hospital Nacional Guillermo Almenara Irigoyen durante julio de 1998 y marzo de 1999. El dRVVT fue el análisis de referencia. RESULTADOS: Hubo 30 muestra
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Setsuko, Suzuki, and Nobuhiro Tomaru. "The effects of plant size and light availability on male and female reproductive success and functional gender in a hermaphrodite tree species, Magnolia stellata." Botany 89, no. 9 (2011): 593–604. http://dx.doi.org/10.1139/b11-051.

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Plant size and light availability may affect male and (or) female reproductive success and their relative contribution (functional gender). To test this hypothesis, we identified parents of 184 seedlings in a local population within a metapopulation of a hermaphroditic, insect-pollinated tree species, Magnolia stellata (Siebold &amp; Zucc.) Maxim., using 14 nuclear and 3 chloroplast microsatellite markers. Parent pairs of all the seedlings were determined, and both seed and pollen parents could be distinguished for 49.5% of the seedlings. We also measured the parents’ plant size (diameter at b
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Almeida, Gustavo Klamer de, and João Caetano Fioravanço. "Yield of 'Royal Gala' apple trees in response to pruning before or after leaf drop." Pesquisa Agropecuária Brasileira 53, no. 4 (2018): 427–34. http://dx.doi.org/10.1590/s0100-204x2018000400004.

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Abstract: The objective of this work was to evaluate different pruning times, performed before or after natural leaf drop, regarding their effects on the yield of 'Royal Gala' apple (Malus domestica) trees. The experiment was carried out in Vacaria, in the state of Rio Grande do Sul, Brazil, on seven-year-old trees in four harvests from 2008/2009 to 2011/2012, using a randomized block design. The following pruning times were tested: 46 days before leaf drop (DBLD); 25 DBLD; 5 DBLD; 15 days after leaf drop (DALD); 36 DALD; 55 DALD; and 75 DALD. All pruning times before natural leaf drop reduced
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Ley, Michael. "DBLP." Proceedings of the VLDB Endowment 2, no. 2 (2009): 1493–500. http://dx.doi.org/10.14778/1687553.1687577.

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Börlin, N., A. Murtiyoso, and P. Grussenmeyer. "IMPLEMENTING FUNCTIONAL MODULARITY FOR PROCESSING OF GENERAL PHOTOGRAMMETRIC DATA WITH THE DAMPED BUNDLE ADJUSTMENT TOOLBOX (DBAT)." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-2/W17 (November 29, 2019): 69–75. http://dx.doi.org/10.5194/isprs-archives-xlii-2-w17-69-2019.

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Abstract. The Damped Bundle Adjustment Toolbox (DBAT) is a free, open-source, toolbox for bundle adjustment. The purpose of DBAT is to provide an independent, open-source toolkit for statistically rigorous bundle adjustment computations. The capabilities include bundle adjustment, network analysis, point filtering, forward intersection, spatial intersection, plotting functions, and computations of quality indicators such as posterior covariance estimates and parameter correlations. DBAT is written in the high-level Matlab language and includes several processing example files. The input format
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Kuzmiak, Cherie Marie, Elodia B. Cole, Donglin Zeng, Laura A. Tuttle, Doreen Steed, and Etta D. Pisano. "Dedicated Three-dimensional Breast Computed Tomography: Lesion Characteristic Perception by Radiologists." Journal of Clinical Imaging Science 6 (March 30, 2016): 14. http://dx.doi.org/10.4103/2156-7514.179428.

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Objectives: To assess radiologist confidence in the characterization of suspicious breast lesions with a dedicated three-dimensional breast computed tomography (DBCT) system in comparison to diagnostic two-dimensional digital mammography (dxDM). Materials and Methods: Twenty women were recruited who were to undergo a breast biopsy for a Breast Imaging-Reporting and Data System (BI-RADS) 4 or 5 lesion evaluated with dxDM in this Institutional Review Board-approved study. The enrolled subjects underwent imaging of the breast(s) of concern using DBCT. Seven radiologists reviewed the cases. Each r
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Chai, Louis YA, Kian Chung Ong, Adrian Kee, Arul Earnest, Fabian CL Lim, and John CM Wong. "A Prospective Cohort Study on the Impact of a Modified Basic Military Training (mBMT) Programme Based on Pre-enlistment Fitness Stratification Amongst Asian Military Enlistees." Annals of the Academy of Medicine, Singapore 38, no. 10 (2009): 862–68. http://dx.doi.org/10.47102/annals-acadmedsg.v38n10p862.

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Introduction: This study objectively evaluates the effectiveness of a 6-week Preparatory Training Phase (PTP) programme prior to Basic Military Training (BMT) for less physically conditioned conscripts in the Singapore Armed Forces. Materials and Methods: We compared exercise test results of a group of less fit recruits who underwent a 16-week modified-BMT (mBMT) programme (consisting of a 6-week PTP and 10-week BMT phase) with their ‘fitter’ counterparts enlisted in the traditional 10-week direct-intake BMT (dBMT) programme in this prospective cohort study consisting of 36 subjects. The main
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Zihni, Ceniz, Peter M. G. Munro, Ahmed Elbediwy, et al. "Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation." Journal of Cell Biology 204, no. 1 (2013): 111–27. http://dx.doi.org/10.1083/jcb.201304064.

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Epithelial cells develop morphologically characteristic apical domains that are bordered by tight junctions, the apical–lateral border. Cdc42 and its effector complex Par6–atypical protein kinase c (aPKC) regulate multiple steps during epithelial differentiation, but the mechanisms that mediate process-specific activation of Cdc42 to drive apical morphogenesis and activate the transition from junction formation to apical differentiation are poorly understood. Using a small interfering RNA screen, we identify Dbl3 as a guanine nucleotide exchange factor that is recruited by ezrin to the apical
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Jiang, Xinke, Wentao Zhang, Yuchen Fang, et al. "Time Series Supplier Allocation via Deep Black-Litterman Model." Proceedings of the AAAI Conference on Artificial Intelligence 39, no. 11 (2025): 11870–78. https://doi.org/10.1609/aaai.v39i11.33292.

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As a typical problem of Spatiotemporal Resource Management, Time Series Supplier Allocation (TSSA) poses a complex NP-hard challenge, aimed at refining future order dispatching strategies to satisfy the trade-off between demands and maximum supply. The Black-Litterman (BL) model, which comes from financial portfolio management, offers a new perspective for the TSSA by balancing expected returns against insufficient supply risks. However, the BL model is not only constrained by manually constructed perspective matrices and spatio-temporal market dynamics but also restricted by the absence of su
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Githinji, George, and Peter C. Bull. "A re-assessment of gene-tag classification approaches for describing var gene expression patterns during human Plasmodium falciparum malaria parasite infections." Wellcome Open Research 2 (September 19, 2017): 86. http://dx.doi.org/10.12688/wellcomeopenres.12053.1.

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PfEMP1 are variant parasite antigens that are inserted on the surface of Plasmodium falciparum infected erythrocytes (IE). Through interactions with various host molecules, PfEMP1 mediate IE sequestration in tissues and play a key role in the pathology of severe malaria. PfEMP1 is encoded by a diverse multi-gene family called var. Previous studies have shown that that expression of specific subsets of var genes are associated with low levels of host immunity and severe malaria. However, in most clinical studies to date, full-length var gene sequences were unavailable and various approaches hav
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Choi, Jeon-Yong, Eun-Chul Kang, and Euy-Joon Lee. "Performance Comparison Study on LFLP and DBLP Daylighting System." Transactions of the Korean Society of Mechanical Engineers B 35, no. 8 (2011): 799–804. http://dx.doi.org/10.3795/ksme-b.2011.35.8.799.

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Chen, Li, Ling Wu, Liu Yang, et al. "TcJAV3–TcWRKY26 Cascade Is a Missing Link in the Jasmonate-Activated Expression of Taxol Biosynthesis Gene DBAT in Taxus chinensis." International Journal of Molecular Sciences 23, no. 21 (2022): 13194. http://dx.doi.org/10.3390/ijms232113194.

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Jasmonates (JAs) are the most effective inducers for the biosynthesis of various secondary metabolites. Currently, jasmonate ZIM domain (JAZ) and its interactors, such as MYC2, constitute the main JA signal transduction cascade, and such a cascade fails to directly regulate all the taxol biosynthesis genes, especially the rate-limit gene, DBAT. Another JA signaling branch, JAV and WRKY, would probably fill the gap. Here, TcJAV3 was the closest VQ-motif-containing protein in Taxus chinensis to AtJAV1. Although TcJAV3 was overexpressed in AtJAV1 knockdown mutant, JAVRi17, the enhanced disease re
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Wang, Lin, and Anke Xue. "Wind Speed Modeling for Wind Farms Based on Deterministic Broad Learning System." Atmosphere 14, no. 8 (2023): 1308. http://dx.doi.org/10.3390/atmos14081308.

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As the penetration rate of wind power in the grid continues to increase, wind speed forecasting plays a crucial role in wind power generation systems. Wind speed prediction helps optimize the operation and management of wind power generation, enhancing efficiency and reliability. However, wind speed is a nonlinear and nonstationary system, and traditional statistical methods and classical intelligent algorithms struggle to cope with dynamically updating operating conditions based on sampled data. Therefore, from the perspective of optimizing intelligent algorithms, a wind speed prediction mode
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Katkovčinová, Zuzana, Martina Lázárová, Katarína Bruňáková, Ján Košuth, and Eva Čellárova. "Expression of dbat and dbtnbt Genes Involved in Paclitaxel Biosynthesis during the Growth Cycle of Taxus baccata L. Callus Cultures." Zeitschrift für Naturforschung C 63, no. 9-10 (2008): 721–30. http://dx.doi.org/10.1515/znc-2008-9-1018.

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The time-course of expression of dbat and dbtnbt genes involved in the later steps of paclitaxel biosynthesis and the intracellular taxane accumulation were investigated through a 64-day subculture interval of VI/M1 and VI/M2 Taxus baccata callus cultures. HPLC proved traces of baccatin III and an intracellular content of paclitaxel up to 90 μg/g DW. The steadystate of the respective gene transcripts was measured by quantitative real-time RT-PCR. The expression profile of dbat and dbtnbt genes was slightly different and varied within the subculture. The highest level of dbat expression was det
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Bai, Zhiliang, Dingyao Zhang, Yan Gao, et al. "Abstract A022: Patho-DBiT: Spatially exploring RNA biology in archival formalin-fixed paraffin- embedded tissues." Molecular Cancer Therapeutics 23, no. 11_Supplement (2024): A022. http://dx.doi.org/10.1158/1538-8514.rnadrivers24-a022.

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Abstract Despite recent breakthroughs in spatial biology, either imaging-based or sequencing-based spatial transcriptomics is largely equivalent to spatial messenger RNA (mRNA) expression quantification. An RNA molecule experiences a complex life cycle involving transcription, splicing, maturation, translation, and degradation . It is highly desirable to profile all these RNA species spanning their life cycle to explore the biology of RNA at genome scale and cellular level. Furthermore, formalin-fixed paraffin-embedded (FFPE) tissues are essential in clinical practice, being the backbone of hu
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Aleena Arif, Ahsan Zubair, and Faiqa Kiran *. "Destination brand attachment: Understanding the path towards loyalty and advocacy." Social Science Review Archives 3, no. 2 (2025): 480–500. https://doi.org/10.70670/sra.v3i2.637.

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Building on attachment theory, this paper investigates the role of consumers' destination brand attachment(DBAT) and self-brand connection(SBC) in building behavioral outcomes namely destination brand loyalty and advocacy towards eco-destination brands. In addition, the study also investigates the mediating role of destination brand image. The study adopts a quantitative approach by using survey to collect data from 240 eco-tourists. The proposed hypotheses were examined with PLS-SEM.The results reveal that DBI partially mediates the relationship between DBAT and DBL, as well as SBC and DBL. F
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Shu, Bowen, Zhenghong Gao, Lin Zhou, and Shusheng Chen. "Numerical Investigations on Unsteady Features of Rounded Trailing Edge Airfoils." International Journal of Aerospace Engineering 2022 (December 28, 2022): 1–17. http://dx.doi.org/10.1155/2022/4362331.

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As a practical rounded trailing edge airfoil for coaxial rotors, DBLN-526 is a fore and aft symmetrical airfoil with two steps on its lower side. This airfoil has been used at the inboard section of the coaxial rotor system. As there are always two eddies behind the airfoil because of its rounded trailing edge, the interaction between the separation and transition should be considered. Thus, the unsteady Reynolds-averaged Navier-Stokes- (RANS-) based γ − Re ¯ θ t model was used to analyze the unsteady transition and separation features. Three different rounded trailing-edge airfoils were compa
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Matthews, Geoffrey M., Sara Gandolfi, Johanna Bruggentheis, et al. "BET Bromodomain Degradation As a Therapeutic Strategy in Multiple Myeloma." Blood 128, no. 22 (2016): 1062. http://dx.doi.org/10.1182/blood.v128.22.1062.1062.

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Abstract Multiple myeloma (MM) remains an incurable malignancy with a clear need for novel therapeutic modalities. Moreover, acquired or de novo resistance to established or novel therapeutics remains a major challenge in this, and other, neoplasias. BET Bromodomain inhibitors (BBIs), including JQ1, have potent anti-MM activity in vitro and in in vivo, but do not provide curative outcome and do not induce apoptosis in many tumor cell types. Recently, a "next-generation" BBI, dBET, that causes degradation of BET Bromodomains (BRDs) through CRBN-mediated ubiquitination has been demonstrated to h
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An, Dong-Shan, Wan-Taek Im, Hee-Chan Yang, et al. "Cellulomonas terrae sp. nov., a cellulolytic and xylanolytic bacterium isolated from soil." International Journal of Systematic and Evolutionary Microbiology 55, no. 4 (2005): 1705–9. http://dx.doi.org/10.1099/ijs.0.63696-0.

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A bacterial strain (DB5T), with polysaccharide-degrading activities, was isolated from garden soil in Daejeon, Republic of Korea. The cells were Gram-positive, aerobic or facultatively anaerobic, non-motile straight rods. Phylogenetic analysis based on 16S rRNA gene sequences showed that this strain belongs to the genus Cellulomonas and that it is most closely related to Cellulomonas xylanilytica LMG 21723T and Cellulomonas humilata ATCC 25174T (98·0 and 97·9 % similarity, respectively). Chemotaxonomic data also supported the classification of strain DB5T in the genus Cellulomonas, i.e. l-orni
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Chiabaut, Nicolas, Michael Küng, Monica Menendez, and Ludovic Leclercq. "Perimeter Control as an Alternative to Dedicated Bus Lanes: A Case Study." Transportation Research Record: Journal of the Transportation Research Board 2672, no. 20 (2018): 110–20. http://dx.doi.org/10.1177/0361198118786607.

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Dedicated bus lanes (DBLs) are a common traffic management strategy in cities as they improve the efficiency of the transit system by preventing buses from getting trapped in traffic jams. Nevertheless, DBLs also have certain disadvantages: they consume space, reduce available capacity for general traffic, and can thus lead to even more congested car traffic situations. It is appealing to find more efficient alternatives that maintain a sufficient network supply for general traffic while guaranteeing high commercial speeds for the bus system. This paper investigates whether perimeter control (
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Mayor, Alfredo, Eduard Rovira-Vallbona, Anand Srivastava, et al. "Functional and Immunological Characterization of a Duffy Binding-Like Alpha Domain from Plasmodium falciparum Erythrocyte Membrane Protein 1 That Mediates Rosetting." Infection and Immunity 77, no. 9 (2009): 3857–63. http://dx.doi.org/10.1128/iai.00049-09.

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ABSTRACT The Duffy binding-like (DBL) domains are common adhesion modules present in Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variants, which are responsible for immune evasion and cytoadherence. Knowledge about how immune responses are acquired against polymorphic DBL domains of PfEMP1 can aid in the development of vaccines for malaria. A recombinant DBLα domain, encoded by R29 var1, which binds complement receptor 1 to mediate rosetting by the P. falciparum laboratory strain R29, was expressed in Escherichia coli, renatured by oxidative refolding to its native form, and
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Murtiyoso, A., P. Grussenmeyer, and N. Börlin. "REPROCESSING CLOSE RANGE TERRESTRIAL AND UAV PHOTOGRAMMETRIC PROJECTS WITH THE DBAT TOOLBOX FOR INDEPENDENT VERIFICATION AND QUALITY CONTROL." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-2/W8 (November 13, 2017): 171–77. http://dx.doi.org/10.5194/isprs-archives-xlii-2-w8-171-2017.

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Photogrammetry has recently seen a rapid increase in many applications, thanks to developments in computing power and algorithms. Furthermore with the democratisation of UAVs (Unmanned Aerial Vehicles), close range photogrammetry has seen more and more use due to the easier capability to acquire aerial close range images. In terms of photogrammetric processing, many commercial software solutions exist in the market that offer results from user-friendly environments. However, in most commercial solutions, a black-box approach to photogrammetric calculations is often used. This is understandable
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Hu, Ruilin, Yajun Du, Jingrong Hu, and Hui Li. "Cross-community shortcut detection based on network representation learning and structural features." Intelligent Data Analysis 27, no. 3 (2023): 709–32. http://dx.doi.org/10.3233/ida-216513.

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As social networks continue to expand, an increasing number of people prefer to use social networks to post their comments and express their feelings, and as a result, the information contained in social networks has grown explosively. The effective extraction of valuable information from social networks has attracted the attention of many researchers. It can mine hidden information from social networks and promote the development of social network structures. At present, many ranking node approaches, such as structural hole spanners and opinion leaders, are widely adopted to extract valuable
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Misan, Aleksandra, Bojana Saric, Ivan Milovanovic, et al. "Phenolic profile and antioxidant properties of dried buckwheat leaf and flower extracts." Chemical Industry and Chemical Engineering Quarterly 23, no. 1 (2017): 39–47. http://dx.doi.org/10.2298/ciceq150704004m.

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Due to a high content of rutin (2-10%), dried buckwheat leaf and flower (DBLF) formulations were shown to be efficient in the treatment of vascular diseases. In order to find a cost effective way for the extraction of antioxidants, the effects of ethanol/water ratio and temperature on the extraction efficiency of phenolic compounds and the mechanisms of antioxidant action of the extracts were tested. Extraction with ethanol/water mixture (80:20, v/v) for 24 h at room temperature, after the mixture was just brought to boil was demonstrated to be an efficient and cheap way for obtaining a high y
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Börlin, N., A. Murtiyoso, and P. Grussenmeyer. "EFFICIENT COMPUTATION OF POSTERIOR COVARIANCE IN BUNDLE ADJUSTMENT IN DBAT FOR PROJECTS WITH LARGE NUMBER OF OBJECT POINTS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLIII-B2-2020 (August 12, 2020): 737–44. http://dx.doi.org/10.5194/isprs-archives-xliii-b2-2020-737-2020.

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Abstract. One of the major quality control parameters in bundle adjustment are the posterior estimates of the covariance of the estimated parameters. Posterior covariance computations have been part of the open source Damped Bundle Adjustment Toolbox in Matlab (DBAT) since its first public release. However, for large projects, the computation of especially the posterior covariances of object points have been time consuming.The non-zero structure of the normal matrix depends on the ordering of the parameters to be estimated. For some algorithms, the ordering of the parameters highly affect the
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Nazário Coelho, Vitor, Rodolfo Pereira Araújo, Haroldo Gambini Santos, Wang Yong Qiang, and Igor Machado Coelho. "A MILP Model for a Byzantine Fault Tolerant Blockchain Consensus." Future Internet 12, no. 11 (2020): 185. http://dx.doi.org/10.3390/fi12110185.

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Mixed-integer mathematical programming has been widely used to model and solve challenging optimization problems. One interesting feature of this technique is the ability to prove the optimality of the achieved solution, for many practical scenarios where a linear programming model can be devised. This paper explores its use to model very strong Byzantine adversaries, in the context of distributed consensus systems. In particular, we apply the proposed technique to find challenging adversarial conditions on a state-of-the-art blockchain consensus: the Neo dBFT. Neo Blockchain has been using th
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