Academic literature on the topic 'Depigmenting disorder'

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Journal articles on the topic "Depigmenting disorder"

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Fabbrocini, G., V. De Vita, N. Fardella, et al. "Skin Needling to Enhance Depigmenting Serum Penetration in the Treatment of Melasma." Plastic Surgery International 2011 (April 7, 2011): 1–7. http://dx.doi.org/10.1155/2011/158241.

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Melasma is a common hypermelanotic disorder affecting the facial area which has a considerable psychological impact on the patient. Managing melasma is a difficult challenge that requires long-term treatment with a number of topical agents, such as rucinol and sophora-alpha. Aims. We aim to compare the combined treatment of skin needling and depigmenting serum with that using depigmenting serum alone in the treatment of melasma, in order to evaluate the use of microneedles as a means to enhance the drug’s transdermal penetration. Methods. Twenty patients were treated with combined skin needlin
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Kandhari, Sanjeev, P. Narasimha Rao, Shehnaz Arsiwala, Anil Ganjoo, Seema Sood, and Dinesh Kumar. "Expert opinion on current trends in hyperpigmentation management: Indian perspective." International Journal of Research in Dermatology 8, no. 1 (2021): 142. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20214925.

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<p class="abstract">Hyperpigmentation is a common pigmentary disorder characterized by increased production of melanin. It is present in Asian skin phototypes, with a higher prevalence in the Indian population. Skin heterogeneity is seen in more than 80% of individuals of all age groups and genders in several cities across India. In children, the prevalence of hyperpigmentary disorders accounts for 1.54 per 1000 children.Sixty expert dermatologists participated in expert group meetings via teleconference webinar to elaborate on the current trends in the management of hyperpigmentary diso
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Mahmood, Farhan, and Renée A. Beach. "Can it make me white again? A case report of 88% phenol as a depigmenting agent in vitiligo." SAGE Open Medical Case Reports 9 (January 2021): 2050313X2199330. http://dx.doi.org/10.1177/2050313x21993307.

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Vitiligo is the most common depigmenting disorder. However, therapies prove to be time-consuming, costly, or slow to show efficacy. Here, we present a case of a 74-year-old female with vitiligo who underwent full-body depigmentation treatment 50 years ago. Brown patches of repigmentation appeared on the patient’s face and arms and were eventually treated with 88% phenol. Patient was later switched to compounded 3% glutathione cream for a more sustained effect. Phenol was an accessible, economical, and easily administrable therapeutic option that can result in short-term depigmentation.
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Bagherani, Nooshin. "The Newest Hypothesis about Vitiligo: Most of the Suggested Pathogeneses of Vitiligo Can Be Attributed to Lack of One Factor, Zinc-α2-Glycoprotein". ISRN Dermatology 2012 (19 червня 2012): 1–8. http://dx.doi.org/10.5402/2012/405268.

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Zinc-α2-glycoprotein (ZAG) is a recently identified adipokine, assigned to the chromosome 7q22.1. It is a multidisciplinary protein, which is secreted in various body fluids. The ZAG plays roles in lipolysis, regulation of metabolism, cell proliferation and differentiation, regulation of melanin synthesis, cell adhesion, immunoregulation, and so forth. Vitiligo is the most common depigmenting skin disorder, characterized by acquired, progressive, and circumscribed amelanosis of the skin and hair. It commonly begins in childhood or young adulthood. The pathogenesis of this disorder is uncertain
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Kemp, E. Helen, Elizabeth A. Waterman, and Anthony P. Weetman. "Immunological pathomechanisms in vitiligo." Expert Reviews in Molecular Medicine 3, no. 20 (2001): 1–22. http://dx.doi.org/10.1017/s1462399401003362.

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Vitiligo is a depigmenting disorder characterised by the loss of melanocytes from the cutaneous epidermis. Although the exact aetiology of vitiligo has not yet been established, the abnormal immune responses frequently observed in vitiligo patients have led to the suggestion that, in some cases, the condition has an autoimmune component. Briefly, circulating autoantibodies and autoreactive T cells that recognise pigment cell antigens have been detected in the sera of a significant proportion of vitiligo patients compared with healthy individuals. In addition, vitiligo is often associated with
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J. Patel, Dharaben, Nehabahen T. Solanki, Dhwaniben R. Makwana, and Kirti S. Parmar. "A STUDY OF CORRELATION BETWEEN THYROID FUNCTION TEST ABNORMALITIES AND TYPES OF VITILIGO." International Journal of Advanced Research 10, no. 12 (2022): 779–83. http://dx.doi.org/10.21474/ijar01/15903.

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Background: Vitiligo is a chronic depigmenting disorder of skin and mucosal membrane which can be associated with many autoimmune cutaneous as well as systemic disorders. Association of vitiligo with various thyroid disorders has been implicated in various studies. Objectives: To evaluate the correlation of thyroid function test abnormalities in various types of vitiligo. Method: This is a case control study in which 82 cases of vitiligo and same number of age group and gender matched controls were enrolled. All patients including cases and controls were subjected to thyroid function tests (T3
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Gavalas, Nikos G., Samia Akhtar, David J. Gawkrodger, Philip F. Watson, Anthony P. Weetman, and E. Helen Kemp. "Analysis of allelic variants in the catalase gene in patients with the skin depigmenting disorder vitiligo." Biochemical and Biophysical Research Communications 345, no. 4 (2006): 1586–91. http://dx.doi.org/10.1016/j.bbrc.2006.05.063.

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Iwanowski, Tomasz, Karol Kołkowski, Roman Janusz Nowicki, and Małgorzata Sokołowska-Wojdyło. "Etiopathogenesis and Emerging Methods for Treatment of Vitiligo." International Journal of Molecular Sciences 24, no. 11 (2023): 9749. http://dx.doi.org/10.3390/ijms24119749.

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Vitiligo is an acquired chronic depigmenting disorder of skin. It is mostly asymptomatic and characterized by amelanotic macules and patches that affects 0.5% to 2% of the world’s population. The etiology of vitiligo has not been clearly elucidated and multiple theories have been proposed regarding the causes of the disorder. Among the most prevalent theories, the genetic predisposition, oxidative stress theory, promotion of cellular stress and pathologic influence of lymphocytes T have been highlighted. As a result of increases in in-depth knowledge concerning the pathogenetic processes in vi
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Furune, Satoshi, Chiaki Kondo, Yuko Takano, et al. "Vitiligo and tumor response in a patient with amelanotic melanoma undergoing nivolumab treatment." International Cancer Conference Journal 11, no. 1 (2021): 46–48. http://dx.doi.org/10.1007/s13691-021-00515-w.

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AbstractVitiligo, an acquired depigmenting disorder of the skin that reacts against normal melanocytes, sometimes occurs as an immune-related adverse event in the treatment of melanoma with immune checkpoint inhibitors. It has been known that the occurrence of vitiligo is associated with a favorable therapeutic response in patients with melanoma, but it is not yet clear whether the association also applies to amelanotic melanoma, a minor subtype of melanoma with little or no melanin pigmentation. We report a patient with amelanotic melanoma of the esophagus who responded well to nivolumab trea
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Amornsiripanitch, S., L. M. Barnes, J. J. Nordlund, L. S. Trinkle, and L. A. Rheins. "Immune studies in the depigmenting C57BL/Ler-vit/vit mice. An apparent isolated loss of contact hypersensitivity." Journal of Immunology 140, no. 10 (1988): 3438–45. http://dx.doi.org/10.4049/jimmunol.140.10.3438.

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Abstract Vitiligo is a human disorder which destroys pigment cells in the skin, ears, eyes, and meningeal tissues and has often been associated with a variety of autoimmune disorders. The C57BL/Ler-vit/vit mouse is a mutant strain that exhibits a loss of epidermal pigment cells and a selective cell-mediated immune deficiency to epicutaneous-administered allergens. This observation is consistent with that observed in humans with vitiligo, who also exhibit loss of contact hypersensitivity (CHS), that appears to be associated with loss of pigment cells from the epidermis. Other cellular immune pa
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Book chapters on the topic "Depigmenting disorder"

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Galappatthy, Priyadarshani, and Deepani Rathnayake. "Depigmenting Agents." In Pigmentary Skin Disorders. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-70419-7_18.

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Müge Acar, Emine. "Vitiligo: Pathogenesis, Clinical Features, and Treatment." In Pigmentation Disorders [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.107208.

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Vitiligo is a depigmenting skin disorder of unknown etiology, which presents with nonscaly, chalky-white macules. Selective loss of melanocytes is the characteristic feature of vitiligo. Of the many theories proposed for melanocyte loss, convergence theory, which suggests that the combination of biochemical, environmental, and immunological factors play a role in the pathophysiology of vitiligo, is currently the most accepted theory. Treatment options include topical and systemic immunosuppressants, phototherapy, and surgical techniques. The subtype, extent, distribution, and activity of disea
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Kasraee, Behrooz. "Skin Depigmenting Agents: Where Do We Stand?" In Pigmentation Disorders [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106791.

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Skin hyperpigmentary disorders are frequent and psychologically disturbing conditions for patients. Skin depigmenting agents have been widely used for the treatment of such disorders. The most efficacious depigmenting agents, such as hydroquinone and the Kligman’s formula, are associated with long-term side effects, and safer skin depigmenting agents, such as kojic acid, arbutin, and niacinamide, might suffer from a significantly lower depigmenting efficacy. Therefore, there is still a need for safe and simultaneously efficacious skin depigmenting compounds. Tranexamic acid and cysteamine are
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Ly, Fatimata. "Pigmentary Disorders in Black Skin from Pathophysiology to Treatment." In Pigmentation Disorders - Etiology and Recent Advances in Treatments. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.109773.

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Pigmentary disorders are frequent and more visible in patients with darker phototypes (Fitzpatrick’s IV–VI). They also have an important psychological impact and are the cause of inappropriate cosmetic practices. Pigmentary disorders comprise a wide range of pathologies, and the pathophysiological mechanisms have evolved considerably in recent years. Pigment disorders vary in their clinical presentation from achromia to hyperpigmentation to hypopigmentation. Inflammatory dermatoses, such as acne, are often complicated by postinflammatory hyperpigmentation; psoriasis and lichen planus are accom
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