Relevant bibliographies by topics / Desmosine

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Desmosine'

Author: Grafiati
Published: 4 June 2021
Last updated: 8 February 2022

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Journal articles on the topic "Desmosine"

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McClintock, Dana E., Barry Starcher, Mark D. Eisner, et al. "Higher urine desmosine levels are associated with mortality in patients with acute lung injury." American Journal of Physiology-Lung Cellular and Molecular Physiology 291, no. 4 (2006): L566—L571. http://dx.doi.org/10.1152/ajplung.00457.2005.

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Desmosine is a stable breakdown product of elastin that can be reliably measured in urine samples. We tested the hypothesis that higher baseline urine desmosine would be associated with higher mortality in 579 of 861 patients included in the recent Acute Respiratory Distress Syndrome Network trial of lower tidal volume ventilation ( 1 ). We also correlated urine desmosine levels with indexes of disease severity. Finally, we assessed whether urine desmosine was lower in patients who received lower tidal volumes. Desmosine was measured by radioimmunoassay in urine samples from days 0, 1, and 3 o
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Starcher, Barry, and Marti Scott. "Fractionation of Urine to Allow Desmosine Analysis by Radioimmunoassay." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 29, no. 1 (1992): 72–78. http://dx.doi.org/10.1177/000456329202900111.

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The present study was designed to re-evaluate the radioimmunoassay for desmosine in urine, which is currently used as a measure of elastin metabolism. Using ion exchange chromatography, gel filtration and affinity chromatography it was shown that at least five other compounds in hydrolysates of human urine competed for desmosine in the RIA. Fractionating the urine prior to hydrolysis with acetone removed one of the major contaminants. The other contaminants could subsequently be removed by extracting the urine hydrolysate with a mixture of chloroform/ethanol (60:40). Samples from nine normal a
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Murakami, Yuko, Rina Suzuki, Hiroto Yanuma, et al. "Synthesis and LC-MS/MS analysis of desmosine-CH2, a potential internal standard for the degraded elastin biomarker desmosine." Org. Biomol. Chem. 12, no. 48 (2014): 9887–94. http://dx.doi.org/10.1039/c4ob01438c.

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Hirose, Mika, Reiko Yokoo, Daisuke Watanabe, Rina Suzuki, Miho Tanigawa, and Toyonobu Usuki. "Synthesis of Multi‐Deuterated Desmosine." ChemistrySelect 5, no. 13 (2020): 3843–46. http://dx.doi.org/10.1002/slct.202000507.

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Schräder, Christoph U., Andrea Heinz, Petra Majovsky, and Christian E. H. Schmelzer. "Fingerprinting Desmosine-Containing Elastin Peptides." Journal of The American Society for Mass Spectrometry 26, no. 5 (2015): 762–73. http://dx.doi.org/10.1007/s13361-014-1075-9.

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Pai, V., A. Guz, G. J. Phillips, N. T. Cooke, D. C. S. Hutchison, and T. D. Tetley. "Urinary desmosine, elastolysis, and lung disease." Metabolism 40, no. 2 (1991): 139–45. http://dx.doi.org/10.1016/0026-0495(91)90164-r.

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Janssen, Rob, Jef Serré, Ianthe Piscaer, et al. "Post hoc analysis of a randomised controlled trial: effect of vitamin D supplementation on circulating levels of desmosine in COPD." ERJ Open Research 6, no. 4 (2020): 00128–2019. http://dx.doi.org/10.1183/23120541.00128-2019.

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BackgroundVitamin D supplementation lowers exacerbation frequency in severe vitamin D-deficient patients with COPD. Data regarding the effect of vitamin D on elastin degradation are lacking. Based on the vitamin's anti-inflammatory properties, we hypothesised that vitamin D supplementation reduces elastin degradation, particularly in vitamin D-deficient COPD patients. We assessed the effect of vitamin D status and supplementation on elastin degradation by measuring plasma desmosine, a biomarker of elastin degradation.MethodsDesmosine was measured every 4 months in plasma of 142 vitamin D-naïve
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Sekhon, H. S., and W. M. Thurlbeck. "Lung growth in hypobaric normoxia, normobaric hypoxia, and hypobaric hypoxia in growing rats. I. Biochemistry." Journal of Applied Physiology 78, no. 1 (1995): 124–31. http://dx.doi.org/10.1152/jappl.1995.78.1.124.

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Adaptive changes in cellular and connective tissue components of the lung after chronic exposure to reduced ambient oxygen and/or pressure were studied. Four-week-old male Sprague-Dawley rats were randomly divided into five groups (n = 12 each): 1) general control, room air (GC); 2) hypobaric normoxic; 3) normobaric hypoxic; 4) hypobaric hypoxic; and 5) weight-matched control, restricted food intake (WMC; weight matched to hypobaric hypoxic animals). Lung growth (lung weight and DNA, RNA, protein, hydroxyproline, and desmosine contents) diminished in WMC compared with GC. Somatic growth decrea
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Zay, K., S. Loo, C. Xie, D. V. Devine, J. Wright та A. Churg. "Role of neutrophils and α1-antitrypsin in coal- and silica-induced connective tissue breakdown". American Journal of Physiology-Lung Cellular and Molecular Physiology 276, № 2 (1999): L269—L279. http://dx.doi.org/10.1152/ajplung.1999.276.2.l269.

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Mineral dusts produce emphysema, and administration of dust to rats results in the rapid appearance of desmosine and hydroxyproline in lavage fluid, confirming that dusts directly induce connective tissue breakdown. To examine the role of neutrophils and α1-antitrypsin (α1-AT) in this process, we instilled silica or coal into normal rats or rats that had been pretreated with antiserum against neutrophils. One day after dust exposure, lavage fluid neutrophils and desmosine and hydroxyproline levels were all elevated; treatment with antiserum against neutrophils reduced neutrophils by 75%, desmo
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TETLEY, T. D., G. J. PHILLIPS, A. GUZ, and B. FOX. "The Blotchy Mouse, Lung Desmosine, and Emphysema." Annals of the New York Academy of Sciences 624, no. 1 (1991): 358. http://dx.doi.org/10.1111/j.1749-6632.1991.tb17048.x.

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Dissertations / Theses on the topic "Desmosine"

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Hopkins, Gemma V. "The mechanism of desmosome internalisation." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493936.

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Desmosomes are intercellular adhesive junctions providing architectural integrity to tissues that are subject to mechanical stress. During wound healing downregulation of desmosomal adhesion is necessary to facilitate tissue remodeling. Ultrastructural observations suggest that downregulation may occur by internalisation of whole desmosomes but the mechanism of downregulation is not understood. Protein kinase C alpha (PKCα) has been shown to colocalise with desmosomes at the wound edge and to modulate their adhesion. This thesis investigates the internalisation of desmosomes with particular re
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Tan, Celia I. C. "A radiological and biochemical perspective on ageing and degeneration of the human thoracic intervertebral disc." University of Western Australia. School of Surgery and Pathology, 2004. http://theses.library.uwa.edu.au/adt-WU2004.0059.

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Disc degenerative changes are directly or indirectly associated with spinal pain and disability. Literature revealed a high prevalence of disc degeneration in the thoracic region, however thoracic MRI degeneration trends and information on disc biochemical matrix constituents are limited for thoracic discs compared to lumbar and cervical discs. The objective of this thesis was to use MRI to investigate the prevalence of disc degenerative changes affecting the human thoracic spine, and to determine the factors affecting spinal disc biochemical matrix. A 3-point subjective MRI grading scale was
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Winfield, Kaye R. "Extraction of desmosines from urine : an indicator for inflammatory lung damage." University of Western Australia. School of Paediatrics and Child Health, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0059.

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[Truncated abstract] Urinary desmosines have been proposed as a biomarker for inflammatory lung damage. Desmosine, a breakdown product of elastin, is an effective marker of the degradation of elastin and has been studied in many disease scenarios where there is acute and chronic lung inflammation. Lung matrix degradation has been proven in vitro and in vivo with many experiments showing that the excess proteases degrades lung matrix. The secretion of proteases by neutrophils is an innate response of the body to the invasion by micro organisms and when secreted in excess, the protective anti-pr
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Winfield, Kaye R. "Extraction of desmosines from urine : an indicator for inflammatory lung damage /." Connect to this title, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0059.

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Lloyd, Susan. "Calcium-independent desmosome adhesion : aquisition, maintenance and modulation." Thesis, University of Southampton, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295856.

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Measures, H. R. "A study of desmosome formation in kidney epithelial cells." Thesis, University of Southampton, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234435.

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Cabral, Rita Meira e. Cruz de Vasconcelos. "The role of desmoplakin and plakoglobin in desmosome associated disease." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/2413.

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Desmosomes are intercellular junctions that connect intermediate filaments (IFs) of adjacent cells within tissues, generating a large and mechanically resilient network. Desmosomes are prominent in epithelia and the myocardium. Their importance for maintenance of the strength and flexibility of these tissues is underlined by mutations in desmosomal genes which compromise skin or heart and in some instances both. This thesis is focused on two obligate plaque proteins of the desmosome, desmoplakin (DP) and plakoglobin (PG), and their role in disease of skin and heart. A novel homozygous nonsense
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ZORILA, FLORESCU SILVANA MARIA. "Alteration du profil d'expression des composants desmosomaux et des jonctions adherentes dans les carcinomes epidermoides de l'oropharynx et leur valeur predictive : etude in vivo et in vitro." Paris 7, 2001. http://www.theses.fr/2001PA07GA02.

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DEPONDT, JOEL. "Evaluation prospective des cytokeratines et des composants desmosomaux comme marqueurs diagnostiques et pronostiques des carcinomees epidermoides de l'oropharynx." Paris 7, 2000. http://www.theses.fr/2000PA07GA01.

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Asimaki, Angeliki. "Arrhythmogenic right ventricular cardiomyopathy, a disease of the desmosome : genetic and functional studies." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1443947/.

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Mutation analysis of the recognized ARVC genes and of further candidate genes was performed on a large cohort of ARVC patients. Several novel mutations were identified and three further desmosomal genes were linked to the disease: plakophilin2, desmocollin2 and desmoglein2. Heart and skin samples from ARVC patients were subjected to microscopic examination and immunohistochemistry to study the effect of the newly-identified mutations on the structure of cell adhesion complexes.;The functional effects of a particular novel mutation were thoroughly examined in vitro. S39_K40insS is the first dom
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Books on the topic "Desmosine"

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Wise, Irene Ann. Modulation of desmosome adhesion by intercellular signals involving protein kinase C. University of Manchester, 1996.

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Syrris, Petros, and Alexandros Protonotarios. Arrhythmogenic right ventricular cardiomyopathy: genetics. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0359.

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Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disorder of the heart muscle which is typically inherited in an autosomal dominant manner. It is believed to be familial in over 50% of cases. A recessive mode of inheritance has also been reported in syndromic cases with cardiocutaneous features. The classic form of the disorder is considered to be ‘a disease of the desmosome’ as pathogenic variants have been identified in five genes encoding key desmosomal proteins: plakoglobin, desmoplakin, plakophilin-2, desmoglein-2, and desmocollin-2. Mutations in these genes account for 30–50%
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Book chapters on the topic "Desmosine"

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Mattey, D. L., A. Suhrbier, E. Parrish, and D. R. Garrod. "Recognition, Calcium and the Control of Desmosome Formation." In Novartis Foundation Symposia. John Wiley & Sons, Ltd., 2007. http://dx.doi.org/10.1002/9780470513408.ch4.

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Kolegraff, Keli, Porfirio Nava, and Asma Nusrat. "Specialized Intercellular Junctions in Epithelial Cells: The Tight Junction and Desmosome." In Cellular Domains. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118015759.ch19.

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Waller, G. R., C. F. Yang, L. F. Chen, et al. "Can Soyasaponin I and Mono- and Bi- Desmosides Isolated from Mungbeans Serve as Growth Enhancers in Mungbeans and Lettuce?" In Advances in Experimental Medicine and Biology. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0413-5_11.

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"Desmosin." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_310998.

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"Desmosome." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_4335.

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"Desmosinol." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0537-5_91.

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"Desmosin to Dextransulfate." In RÖMPP Lexikon Chemie, edited by Jürgen Falbe and Manfred Regitz. Georg Thieme Verlag, 1997. http://dx.doi.org/10.1055/b-0036-135449.

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"van Deemter-Gleichung to Desmosin." In RÖMPP Lexikon Chemie, edited by Jürgen Falbe and Manfred Regitz. Georg Thieme Verlag, 1997. http://dx.doi.org/10.1055/b-0036-135448.

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Lie, Pearl P. Y., C. Yan Cheng, and Dolores D. Mruk. "The Biology of the Desmosome-Like Junction." In International Review of Cell and Molecular Biology. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-385859-7.00005-7.

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Beggs, Reena R., William F. Dean, and Alexa L. Mattheyses. "dSTORM Imaging and Analysis of Desmosome Architecture." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/7651_2020_325.

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Conference papers on the topic "Desmosine"

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Spanbroek, Michiel, Jody Van den Ouweland, Twan Beijers, Henny Van Daal, Richard Dekhuijzen, and Rob Janssen. "Short-term stability of the mature elastin degradation biomarker plasma desmosine and influence of smoking on plasma desmosine levels." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa3973.

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Lindberg, Claes, Henrik Lindberg, Sven Kjellström, et al. "Urinary Desmosine Excretion Is Strongly Influenced By Age And Gender." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5959.

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Syed, Maaz, Zaid Iskander, Alexander Fletcher, et al. "BS7 Plasma desmosine as a biomarker in acute aortic syndrome." In British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021. BMJ Publishing Group Ltd and British Cardiovascular Society, 2021. http://dx.doi.org/10.1136/heartjnl-2021-bcs.205.

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Huang, Jeffrey T. J., Elena Kuzmanova, Alison Dicker, et al. "Desmosine is a predictor of long-term cardiovascular mortality in bronchiectasis." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.4718.

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Mordi, Ify, Rachael Forsythe, Matthew Bown, et al. "65 The novel plasma biomarker desmosine, a marker of elastin breakdown, is an independent predictor of abdominal aortic aneurysm events independent of aneurysm size." In British Cardiovascular Society Annual Conference ‘High Performing Teams’, 4–6 June 2018, Manchester, UK. BMJ Publishing Group Ltd and British Cardiovascular Society, 2018. http://dx.doi.org/10.1136/heartjnl-2018-bcs.65.

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Iskandar, Zaid, Jeffrey Huang, Lynn Miller, et al. "126 Urinary desmosine, a biomarker of elastin degradation is significantly elevated and associated with maximum aortic root size and aortic Z-scores in patients with bicuspid aortic valve." In British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019. BMJ Publishing Group Ltd and British Cardiovascular Society, 2019. http://dx.doi.org/10.1136/heartjnl-2019-bcs.123.

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Baron, Maayan, and Trey Ideker. "Abstract 178: Desmosome mutations in melanoma promote cellular proliferation and disease progression." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-178.

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Sheu, Jim J., Brian Y. Kuo, Chia-Cheng Wu, Jacky Yang, and Chih-Mei Chen. "Abstract 4504: Functional roles of KRT6-KRT14 fusion variant 7 in desmosome remodeling and cell spreading/migration." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-4504.

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