Academic literature on the topic 'Detoxification mechanisms'

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Journal articles on the topic "Detoxification mechanisms"

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Barrett, J. "Helminth detoxification mechanisms." Journal of Helminthology 71, no. 2 (1997): 85–90. http://dx.doi.org/10.1017/s0022149x0001573x.

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Detoxification mechanisms in parasitic helminths have not been extensively studied, despite their obvious relevance to drug development and drug resistance. Differences in detoxification enzymes between the parasite and its host may be exploitable in the design of pro-drugs, whilst selective inhibition of the parasites protective enzymes could increase their sensitivity to drug action and also make them more susceptible to the host's defence mechanisms.
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Pinto, A. P., A. de Varennes, M. L. S. Gonçalves, and A. M. Mota. "Sorghum Detoxification Mechanisms." Journal of Plant Nutrition 29, no. 7 (2006): 1229–42. http://dx.doi.org/10.1080/01904160600767450.

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Федорович, Д. В., М. В. Гончар, Г. П. Кшемінська, et al. "MECHANISMS OF CHROMATE DETOXIFICATION IN YEASTS." Microbiology&Biotechnology, no. 3(7) (September 15, 2009): 15–21. http://dx.doi.org/10.18524/2307-4663.2009.3(7).102846.

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Martinez-Finley, Ebany J., and Michael Aschner. "Revelations from the NematodeCaenorhabditis eleganson the Complex Interplay of Metal Toxicological Mechanisms." Journal of Toxicology 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/895236.

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Metals have been definitively linked to a number of disease states. Due to the widespread existence of metals in our environment from both natural and anthropogenic sources, understanding the mechanisms of their cellular detoxification is of upmost importance. Organisms have evolved cellular detoxification systems including glutathione, metallothioneins, pumps and transporters, and heat shock proteins to regulate intracellular metal levels. The model organism,Caenorhabditis elegans(C. elegans), contains these systems and provides several advantages for deciphering the mechanisms of metal detox
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Bozoğlu, Faruk. "Different mycotoxin inactivation applications and their inactivation mechanisms." Zbornik Matice srpske za prirodne nauke, no. 117 (2009): 27–35. http://dx.doi.org/10.2298/zmspn0917027b.

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Control of mycotoxins is the need of the hour, since their occurrence in foods and feeds is continuously posing threats to both health and economics all over the world. Besides the post-harvest preventive measures, it is important that suitable detoxification methods must be developed for inactivating or removing mycotoxins from the contaminated commodities, as the toxins are also produced by Aspergillus flavus and A. parasiticus even during pre-harvest stages of crop production. Several physical and chemical detoxification methods developed so far have been critically discussed in different r
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Shimshoni, Jakob A., and Shimon Barel. "Honeybees (Apis mellifera) toxicology and detoxification mechanisms." Science of The Total Environment 990 (August 2025): 179902. https://doi.org/10.1016/j.scitotenv.2025.179902.

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Li, Ting, Yifan Wang, and Nannan Liu. "Synergism Study for Investigating Possible Mechanisms of Insecticide Resistance in Mosquitoes." Cold Spring Harbor Protocols 2023, no. 7 (2023): pdb.prot108042. http://dx.doi.org/10.1101/pdb.prot108042.

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Metabolic detoxification, in which insecticides are metabolized by enzymes, including cytochrome P450s, hydrolases, and glutathione-S-transferases (GSTs), to become more polar and less toxic, is one of the major mechanisms involved in the development of insecticide resistance. Piperonyl butoxide (PBO),S,S,S,-tributylphosphorotrithioate (DEF), and diethyl maleate (DEM) are inhibitors of P450s, hydrolases, and GSTs, respectively, and are frequently used as insecticide synergists in assessing the metabolic mechanisms that may be involved in the detoxification of insecticides and in the developmen
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Chen, Gaigai, Bowen Han, Wene Nan, and Xiaobo Dong. "Cadmium Tolerance and Detoxification Mechanisms of Lentinula edodes: Physiology, Subcellular Distribution, and Chemical Forms." Microorganisms 13, no. 1 (2025): 62. https://doi.org/10.3390/microorganisms13010062.

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Lentinula edodes has a strong cadmium-enrichment ability, posing a potential threat to human health. However, the cadmium tolerance and detoxification mechanisms of Lentinula edodes are not understood. We investigated the physiological responses, subcellular distribution, and chemical forms of cadmium in two Lentinula edodes strains (1504 and L130) with contrasting cadmium tolerance. The results showed that appropriate, low-level cadmium promoted mycelial growth, and higher cadmium exposure induced obvious inhibition of mycelial growth by damaging the cell wall and membrane structure and trigg
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Bian, Dan-Dan, Yan-Xia Shi, Kai-Wen Shi, Hui-Cong Du, Bo-Ping Tang, and Qiu-Ning Liu. "Insights into Lead Toxicity and Detoxification Mechanisms in the Silkworm, Bombyx mori." Insects 16, no. 7 (2025): 699. https://doi.org/10.3390/insects16070699.

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Bombyx mori, a key lepidopteran model with economic importance, is highly susceptible to environmental heavy metal pollution. This study investigated the mechanisms of Pb toxicity and the associated detoxification and metabolic defense responses in silkworms, employing transcriptome sequencing, enzyme activity assays, and histopathological analysis. Pb exposure caused significant histopathological changes and apoptosis in the fat body, marked by structural disorganization, swollen adipocytes, and degraded extracellular matrix. Molecular analysis showed activation of antioxidant defenses, with
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Luo, Jin-Song, and Zhenhua Zhang. "Mechanisms of cadmium phytoremediation and detoxification in plants." Crop Journal 9, no. 3 (2021): 521–29. http://dx.doi.org/10.1016/j.cj.2021.02.001.

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Dissertations / Theses on the topic "Detoxification mechanisms"

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Pillai, Jitesh Kannan. "Mechanisms of Arsenic Detoxification and Resistance." FIU Digital Commons, 2014. http://digitalcommons.fiu.edu/etd/1699.

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Arsenic is a ubiquitous environmental toxic substance. As a consequence of continual exposure to arsenic, nearly every organism, from Escherichia coli to humans have evolved arsenic detoxification pathways. One of the pathways is extrusion of arsenic from inside the cells, thereby conferring resistance. The R773 arsRDABC operon in E. coli encodes an ArsAB efflux pump that confers resistance to arsenite. ArsA is the catalytic subunit of the pump, while ArsB forms the oxyanion conducting pathway. ArsD is an arsenite metallochaperone that binds arsenite and transfers it to ArsA. The interaction o
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Hamel, Robert D. "Aluminum detoxification mechanisms in Pseudomonas fluorescens." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0025/MQ31433.pdf.

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Choudhury, Hassanul Ghani. "Structural and functional studies of bacterial detoxification mechanisms." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/39387.

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Bacterial multidrug resistance is a prominent issue with an ever-increasing amount of drugs becoming ineffective in treating bacterial infections. The elucidation of the 3D structure of bacterial resistance proteins has become extremely important in the development of new antimicrobials. Bacteria can sense external stimuli and regulate the expression of genes that can confer antibiotic resistance. Response regulators are capable of binding DNA both in their phosphorylated and unphosphorylated states, upregulating gene expression. The crystal structure of the unphosphorylated dimeric Escherichi
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Butko, Emerald Claire. "Molecular mechanisms of cadmium detoxification and long distance transport in plants." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p1452831.

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Thesis (M.S.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed June 16, 2008). Available via ProQuest Digital Dissertations. Includes bibliographical references.
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Van, Egmond Roger Albert. "The effects of organic pollution on fish detoxification mechanisms and reproduction." Thesis, Edinburgh Napier University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386002.

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Arkenberg, Anke. "Mechanisms of anaerobic nitric oxide detoxification by Salmonella enterica serovar Typhimurium." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/48768/.

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Salmonella is the cause of millions of food- and water-borne infections worldwide. Systemic infection and gastroenteritis are the main diseases and often prove fatal to immunocompromised patients. Key to Salmonella’s pathogenicity is the survival of several components of the innate immune system encountered during infection. Reactive oxygen and nitrogen species (ROS and RNS) are an integral part of this antibacterial defence of the immune system. Exposure to ROS and RNS occurs within phagocytic immune cells such as macrophages, where such generation of radicals is used to combat pathogens. NO
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Pantoja, Munoz Leonardo. "The mechanisms of arsenic detoxification by the green microalgae chlorella vulgaris." Thesis, Middlesex University, 2014. http://eprints.mdx.ac.uk/13252/.

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The mechanisms of arsenic interaction with the green microalga Chlorella vulgaris (C. vulgaris) and the potential for its bio-remediation from water were investigated. This was made possible by the development of an improved arsenic extraction from C. vulgaris, leading to successful glutathione and phytochelatins (GSH/PC) complex speciation analysis with 71.1% efficiency. The response of C. vulgaris when challenged by As(III), As(V) and dimethylarsinic acid (DMA) was assessed through experiments on adsorption, efflux and speciation of arsenic (reduction, oxidation, methylation and chelation wi
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FERRARI, MARCO. "INVESTIGATIONS ON THE DETOXIFICATION MECHANISMS OF THE MALARIA VECTOR ANOPHELES STEPHENSI." Doctoral thesis, Università degli Studi di Milano, 2018. http://hdl.handle.net/2434/563070.

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Il lavoro di tesi si è focalizzato sulla risposta del defensoma ad uno stimolo chimico in Anopheles stephensi, il principale vettore malarico nel sud dell’Asia. La malaria è una malattia parassitaria che ha come agenti eziologici parassiti appartenente al genere Plasmodio, di cui cinque specie sono note per essere responsabili per la malattia nell’uomo. Secondo l’Organizzazione Mondiale della Sanità (World Health Organization, WHO) la malaria ha causato nel 2016 circa 445.000 morti e 216 milioni di casi, rappresentando una minaccia alla salute delle popolazioni che vivono in zone endemiche ed
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Santini, Olivier. "Effects of copper on calcium metabolism and detoxification mechanisms in freshwater bivalve species of "Anodonta." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0397/document.

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Le Cuivre (Cu) appartient aux métaux majeurs contaminant les écosystèmes dulcicoles européens. Les bivalves sont des filtreurs qui bioaccumulent fortement les métaux lourds comme le Cu, lequel, en excès cause de graves troubles métaboliques, et physiologiques. Le but de cette thèse est d'étudier les mécanismes de toxicité et de détoxication du cuivre chez Anodonta cygnea et Anodonta anatina, bivalves largement répandus dans les eaux continentales. L'effet du Cu a d'abord été étudié sur le transport cellulaire du calcium (Ca). Le Ca intervient dans de nombreux processus biologiques et le métabo
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Singh, Satish Kumar. "Mechanisms of Bacterial Copper Detoxification and Oxygen Reduction in CueO and Chemotactic Signal Amplification by Receptor Clustering." Diss., The University of Arizona, 2009. http://hdl.handle.net/10150/194765.

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CueO is a multicopper oxidase and catalyses the four-electron reduction of dioxygen to water and functions to protect Escherichia coli against copper-induced toxicity. The mechanism of oxygen reduction in multicopper oxidases has been well studied, but the key structures of the reaction intermediates are not known. A combination of kinetic measurements, mutagenesis and X-ray crystallographic studies were conducted to entrap and structurally characterize the reaction states in CueO. CueO has a methionine-rich insert and a labile copper binding site, two features found only in multicopper oxidas
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Books on the topic "Detoxification mechanisms"

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Hamel, Robert D. Aluminum detoxification mechanisms in Pseudomonas fluorescens. Laurentian University, Chemistry and Biochemistry Department, 1997.

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Bélanger, Guy. The role of phosphates in the aluminium detoxification mechanism of Pseudomonas fluorescens. Laurentian University, 1991.

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Biochemical Mechanisms of Detoxification in Higher Plants. Springer-Verlag, 2006. http://dx.doi.org/10.1007/3-540-28997-6.

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Kvesitadze, George, Gia Khatisashvili, Tinatin Sadunishvili, and Jeremy J. Ramsden. Biochemical Mechanisms of Detoxification in Higher Plants: Basis of Phytoremediation. Springer London, Limited, 2006.

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Kvesitadze, George, Gia Khatisashvili, Tinatin Sadunishvili, and Jeremy J. Ramsden. Biochemical Mechanisms of Detoxification in Higher Plants: Basis of Phytoremediation. Springer, 2010.

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Biochemical Mechanisms of Detoxification in Higher Plants : Basis of Phytoremediation. Springer, 2006.

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Kumar, Vineet, Maulin P. Shah, and Gaurav Saxena. Bioremediation for Environmental Sustainability: Toxicity, Mechanisms of Contaminants Degradation,Detoxification and Challenges. Elsevier, 2020.

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Kumar, Vineet, Maulin P. Shah, and Gaurav Saxena. Bioremediation for Environmental Sustainability: Toxicity, Mechanisms of Contaminants Degradation, Detoxification and Challenges. Elsevier, 2020.

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Frid, Christopher L. J., and Bryony A. Caswell. Toxicology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198726289.003.0002.

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To determine whether or not a contaminant has the potential to become a pollutant, its biological effects must first be established. The scientific discipline of toxicology considers the measurement of toxins, their mechanisms and the effects they have on the environment, its inhabitants and on human health. This chapter describes how contaminants behave in marine environments, how organisms are exposed to them and how they respond at the molecular, individual, population and ecosystem levels. Marine organisms exhibit a range of different responses and detoxification mechanisms that are used a
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Modir, Shahla J., and Joel Morris. Traditional Chinese Medicine (TCM) and Acupuncture Approach to Addiction. Edited by Shahla J. Modir and George E. Muñoz. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190275334.003.0016.

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The first half of this chapter paints a broad overview of TCM (traditional Chinese medicine) with a focus on addiction. The second half details the Western studies, which address specific addictive substances. A glimpse of TCM’s history in the context of the medical models is discussed. The Western medical model is compared to and differentiated from TCM. Yin-yang and 5-element theory are detailed. The Zang Fu patterns are examined along with the principles of treatment and recognition of patterns. The 3 treasures (jing, qi, and shen) are discussed. Acupuncture was serendipitously found to be
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Book chapters on the topic "Detoxification mechanisms"

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Cumming, Jeffrey M., Bradley J. Sinclair, Charles A. Triplehorn, et al. "Detoxification Mechanisms in Insects." In Encyclopedia of Entomology. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_891.

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Martinez-Finley, Ebany J., and Michael Aschner. "Arsenic, Mechanisms of Cellular Detoxification." In Encyclopedia of Metalloproteins. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1533-6_437.

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Kudryasheva, N. S., A. S. Tarasova, and E. S. Fedorova. "Mechanisms of Detoxification by Humic Substances." In Functions of Natural Organic Matter in Changing Environment. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-5634-2_95.

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Chen, Tongbin, Mei Lei, Xiaoming Wan, Xiaoyong Zhou, and Jun Yang. "Arsenic Hyperaccumulation Mechanisms: Absorption, Transportation and Detoxification." In SpringerBriefs in Environmental Science. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-7820-5_2.

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Gupta, Dharmendra K., Sudhakar Srivastava, H. G. Huang, Maria C. Romero-Puertas, and Luisa M. Sandalio. "Arsenic Tolerance and Detoxification Mechanisms in Plants." In Soil Biology. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-21408-0_9.

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Buhler, Donald R., Cristobal L. Miranda, Bogdan Kedzierski, and Ralph L. Reed. "Mechanisms for Pyrrolizidine Alkaloid Activation and Detoxification." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5877-0_75.

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Peña-Salamanca, Enrique J., Ana Lucia Rengifo-Gallego, and Neyla Benitez-Campo. "Detoxification Mechanisms of Heavy Metals by Algal-Bacteria Consortia." In Handbook of Marine Macroalgae. John Wiley & Sons, Ltd, 2011. http://dx.doi.org/10.1002/9781119977087.ch28.

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Cadenas, Enrique. "Mechanisms of Oxygen Activation and Reactive Oxygen Species Detoxification." In Oxidative Stress and Antioxidant Defenses in Biology. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-9689-9_1.

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Jain, Gagan, Gurvarinder Kaur, Rashmi Mishra, et al. "Perspective of Biotechnological Mechanisms of Metalloid Detoxification in Plants." In Metalloids in Biology. CRC Press, 2025. https://doi.org/10.1201/9781032673592-18.

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Gupta, Dharmendra Kumar, Hildegarde Vandenhove, and Masahiro Inouhe. "Role of Phytochelatins in Heavy Metal Stress and Detoxification Mechanisms in Plants." In Heavy Metal Stress in Plants. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38469-1_4.

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Conference papers on the topic "Detoxification mechanisms"

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Xu, C., M. Liu, Y. Fan, D. Cui, H. Xu, and R. Ma. "Application of atmospheric cold plasma for zearalenone detoxification in cereals: Kinetics, mechanisms, and cytotoxicity analysis." In 2024 IEEE International Conference on Plasma Science (ICOPS). IEEE, 2024. http://dx.doi.org/10.1109/icops58192.2024.10626072.

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Di Sansebastiano, Gian-Pietro, Fabrizio Barozzi, Erika Sabella, et al. "Vacuolar Sorting Mechanisms are Differently Influenced by Detoxification Processes." In 1st Electronic Conference on Molecular Science. MDPI, 2015. http://dx.doi.org/10.3390/ecms-1-a001.

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Di Sansebastiano, Gian-Pietro, Fabrizio Barozzi, Erika Sabella, et al. "Vacuolar Sorting Mechanisms are Differently Influenced by Detoxification Processes." In 1st Electronic Conference on Molecular Science. MDPI, 2016. http://dx.doi.org/10.3390/ecms-1-a002.

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Eiden, Amanda L. "Detection of acaricide resistance and metabolic detoxification mechanisms inRhipicephalus sanguineus." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.107353.

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Suzina, N. E., and I. P. Solyanikova. "Adaptive ultrastructural mechanisms of bacterial cells in conditions of microbial detoxification of polluted soils." In XXVIII Российская конференция по электронной микроскопии и VI школа молодых учёных "Современные методы электронной, зондовой микроскопии и комплементарные методы в исследованиях наноструктур и наноматериалов". Crossref, 2020. http://dx.doi.org/10.37795/rcem.2020.90.31.075.

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Mueller, J., V. Rausch, T. Peccerella, O. Elshaarawy, and S. Mueller. "The role of PNPLA3 and MBOAT7 during alcohol detoxification: Different mechanisms for fibrosis development." In 36. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0039-3402119.

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Olefirenko, M., and Tatyana Lukaschuk. "THE INFLUENCE OF ARSENIC ON THE BODY." In II All-Russian Scientific and Practical Conference of students, teachers, practitioners "Education-Science-Practice". Autonomous Non-Profit Educational Organization of Higher Education "Kuban Institute of Vocational Education", 2025. https://doi.org/10.64007/conferencearticle_683d99f69e94f4.66376142.

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Arsenic is one of the most toxic elements, negatively affecting the human body even in small doses. Its compounds are widely distributed in the environment, increasing the risk of chronic poisoning. The article examines the mechanisms of arsenic’s impact at the cellular level, main routes of entry into the body, and health consequences, including the development of cancer, damage to the nervous and cardiovascular systems. Special attention is paid to poisoning prevention and detoxification methods.
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Rausch, V., J. Mueller, I. Silva, et al. "Role of PNPLA3 rs738409 and MBOAT7 rs626283 during alcohol detoxification: Indication of different mechanisms for fibrosis development." In 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0038-1677096.

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Mueller, Johannes, Shijin Wang, Cheng Chen, Omar Elshaarawy, Vanessa Rausch, and Sebastian Mueller. "The role of PNPLA3, MBOAT7 and TM6SF2 during alcohol detoxification: different mechanisms of fibrosis and steatosis development." In 38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag, 2022. http://dx.doi.org/10.1055/s-0041-1740686.

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Tang, Chunfang, Riqing Zhang, Shizhi Wen, and Kelin Li. "Detoxification Mechanism of Plant to Cd: Subcellular Distribution and Forms of Cd in Typha latifolia L." In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5162634.

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Reports on the topic "Detoxification mechanisms"

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Morin, Shai, Gregory Walker, Linda Walling, and Asaph Aharoni. Identifying Arabidopsis thaliana Defense Genes to Phloem-feeding Insects. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699836.bard.

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The whitefly (Bemisia tabaci) is a serious agricultural pest that afflicts a wide variety of ornamental and vegetable crop species. To enable survival on a great diversity of host plants, whiteflies must have the ability to avoid or detoxify numerous different plant defensive chemicals. Such toxins include a group of insect-deterrent molecules called glucosinolates (GSs), which also provide the pungent taste of Brassica vegetables such as radish and cabbage. In our BARD grant, we used the whitefly B. tabaci and Arabidopsis (a Brassica plant model) defense mutants and transgenic lines, to gain
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Kapulnik, Yoram, and Donald A. Phillips. Isoflavonoid Regulation of Root Bacteria. United States Department of Agriculture, 1996. http://dx.doi.org/10.32747/1996.7570561.bard.

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The overall objective of this project was to develop a conceptual framework for enhancing root colonization by beneficial bacteria. To accomplish this aim we tested the hypothesis that production and excretion of the plant phytoalexin medicarpin can be used for creation of a special niche along the legume roots, where beneficial microorganism, such as rhizobium, will have a selective advantage. On the Israeli side it was shown that higher medicarpin levels are exuded following the application of Rhizobium meliloti to the rhizosphere but the specific biochemical pathway governing medicarpin pro
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