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Dissertations / Theses on the topic 'Development organism'

Author: Grafiati

Published: 28 May 2022

Last updated: 30 July 2025

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1

Corris, Amanda B. "Organism-Environment Codetermination: The Biological Roots of Enactivism." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1593266129358889.

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2

Mustow, R. E. "Aspects of dental plaque development in laboratory models." Thesis, University of Bristol, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379543.

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3

Mandrekar, Noopur. "Characterization of a novel component of Wnt signaling pathway using zebrafish as a model organism." Diss., Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/400345.

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Biology<br>Ph.D.<br>Wnt signaling plays important role in many aspects of embryogenesis such as cell proliferation, cell fate specification, cell polarity and organogenesis(Clevers 2006, van Amerongen and Nusse 2009). Wnt ligands have been shown to activate several intra-cellular signaling cascades, including the canonical or Wnt/-catenin dependent pathway and the non-canonical or -catenin independent pathway. Dishevelled (Dvl) occupies a key position at crossroads of all branches of Wnt signaling cascade. To understand, how Dishevelled (Dvl) may channel signaling into the downstream branches,

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4

Sharifi-Yazdi, M. K. "Development of an impedance method for the rapid detection of Escherichia coli." Thesis, University of Strathclyde, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382477.

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5

Радчук, Л. І., та У. П. Огієнко. "Роль генотипу та факторів зовнішнього середовища у розвитку організму". Thesis, Видавництво СумДУ, 2010. http://essuir.sumdu.edu.ua/handle/123456789/21186.

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Сукупність спадкових факторів організму (генів, хромосом, мітохондрій, пластид) називають генотипом. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/21186

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6

Falcinelli, Silvia. "Probiotic administration as emerging biotechnology to improve the development, growth and metabolism of aquatic organism." Doctoral thesis, Università Politecnica delle Marche, 2015. http://hdl.handle.net/11566/242922.

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I probiotici vengono definiti dalla FAO e dalla WHO come “organismi vivi che, se somministrati in quantità adeguata, apportano beneficio alla salute dell'ospite”. Per tale ragione, negli ultimi anni, essi sono stati ampiamente impiegati sia in campo biomedico sia in acquacoltura, come potenziali agenti bio-terapeutici nella cura di molte malattie e al fine di migliorare lo sviluppo dell’organismo allevato. Numerose ricerche scientifiche effettuate negli ultimi decenni hanno ampliato le conoscenze sulle funzioni dell’intestino, ponendo l’attenzione, in particolare, sul microbiota intestinale, l

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Kettle, Christopher Simon. "Segment number variation in Strigamia maritima, a new model organism for investigating the evolution of development." Thesis, University of Sunderland, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391148.

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8

AVELLA, MATTEO ALESSANDRO. "Probiotics and fish development: studies of molecular changes in the host organism induced by beneficial bacteria." Doctoral thesis, Università Politecnica delle Marche, 2010. http://hdl.handle.net/11566/242165.

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9

Lidron, Elisa. "The role of MCU in vertebrate development and physiology using zebrafish (Danio rerio) as a model organism." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3426699.

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Calcium signaling is fundamental for decoding a variety of extra- and intra-cellular signaling pathways and for the regulation of many cellular functions. Mitochondria play a fundamental role in controlling Ca2+ dynamics inside the cell. Their strategic subcellular distribution ensures the efficient coupling between the release of Ca2+ from the stores and its uptake into the organelle, thus guaranteeing the control of the cell death/cell survival pathways and of the energy homeostasis. Since the identification of the mitochondrial calcium uniporter (MCU) and its regulators, the biochemical and

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10

Akande, Motunrayo Ganiyat. "The toxicological evaluation of sewage effluents and pharmaceuticals with the use of zebrafish as a model organism /." Uppsala : Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2008. http://epsilon.slu.se/10691471.pdf.

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11

Sillapawattana, Panwad Fay Verfasser], Andreas [Verfasser] [Schäffer, and Henner [Akademischer Betreuer] Hollert. "Development of ecotoxicity testing in the standard organism Folsomia candida (Collembola) / Panwad Fay Sillapawattana, Andreas Schäffer ; Betreuer: Henner Hollert." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://d-nb.info/1156923697/34.

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12

Sillapawattana, Panwad Fay [Verfasser], Andreas [Verfasser] Schäffer, and Henner [Akademischer Betreuer] Hollert. "Development of ecotoxicity testing in the standard organism Folsomia candida (Collembola) / Panwad Fay Sillapawattana, Andreas Schäffer ; Betreuer: Henner Hollert." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://d-nb.info/1156923697/34.

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13

Faggianelli-Conrozier, Nathalie. "Deciphering the roles of Klf2a, Klf2b and Egr1 transcription factors in heart valve development using zebrafish as model organism." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ128.

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La circulation du flux sanguin à sens unique dans le système cardiovasculaire des vertébrés est assurée par les valves cardiaques. Leur formation est très contrôlée au cours du développement embryonnaire. Cependant, il arrive que celle-ci soit défectueuse, et donc à l’origine de maladies cardiaques congénitales. Ces maladies représentent une des causes majeures de décès à la naissance. L’étude de la formation des valves cardiaques constitue donc un champ de recherche majeur. Dans cette thèse, nous avons utilisé le poisson zèbre, comme animal d’étude modèle pour étudier la formation des valves

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14

Fruberg, Caroline, and My Jonsson. "Olika modellering av vårdprocesser utifrån metaforiska perspektiv : – Skapar det nya drivkrafter för processutveckling?" Thesis, Linnaeus University, School of Computer Science, Physics and Mathematics, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-7469.

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<p>The study was conducted in Jönköping County Chamber of fibrillation and is about change and improvement of process modeling technology. The process for treating patients with fibrillation is in the need to evolve and improve. In order to develop the care they needed a current state description which usually is made with the traditional process modeling tool.</p><p>Many scientists and health professionals is in the opinion that this technology gives a too rigid image to describe the care processes. It also does not sufficiently take into account the human aspects. This reasoning suggests tha

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Michna, Raphael [Verfasser], Jörg [Akademischer Betreuer] Stülke, Burkhard [Akademischer Betreuer] Morgenstern, and Fabian Moritz [Akademischer Betreuer] Commichau. "The development of an integrated database of the model organism Bacillus subtilis / Raphael Michna. Betreuer: Jörg Stülke. Gutachter: Jörg Stülke ; Burkhard Morgenstern ; Fabian Moritz Commichau." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1081820349/34.

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16

Cyrus-Kent, Chlo. "Appendage development and early distal-less regulation in arthropods : a study of the chelicerate Tetranychus urticae (Acarida)." Thesis, University of Cambridge, 2007. https://www.repository.cam.ac.uk/handle/1810/241413.

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A major goal of evolutionary developmental biology is to explore mechanisms and events underlying evolution of the myriad body plan morphologies expressed both genetically and phenotypically within the animal kingdom. Arthropods exhibit an astounding array of morphological diversity both within and between representative sub-phyla, thus providing an ideal phylum through which to address questions of body plan innovation and diversification. Major arthropod groups are recognised and defined by the distinct form and number of articulated appendages present along the antero-posterior axis of thei

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17

Delomas, Thomas Allin. "Sex determination and interspecies hybridization in zebrafish Danio rerio and pearl danio D. albolineatus." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1522574215273393.

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18

Endres, Annelize. "Getraumatiseerde adolessente se soeke na hoop : ‘n pastorale model (Afrikaans)." Thesis, University of Pretoria, 2008. http://hdl.handle.net/2263/28780.

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South Africa has a high incidence of crime where violence is particularly being committed against adolescents. Trauma has a disruptive influence on the development of adolescents. There is a lack of research focussing on pastoral counselling from a postmodern perspective regarding adolescents who experience acute trauma. This study makes use of three theories to make a meaningful contribution namely those of Rudolf Otto (1869 – 1937), René Girard (1923 - ) and Donald Capps (1990, 1993, 1994,1996). This study finds Otto`s theory about the numinous useful to assist traumatized adolescents on the

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19

Martí, Solans Josep. "Oikopleura dioica com a model animal per investigar l'impacte de les pèrdues gèniques en l'Evo-Devo: les vies de senyalització de l'àcid retinoic i Wnt com a cas d'estudi." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/663443.

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El creixent nombre de genomes seqüenciats està posant de manifest que la pèrdua gènica és un fenomen recurrent que pot haver generat diversitat al llarg de la història evolutiva dels diferents grups d’organismes. En aquest sentit, un dels grans reptes en el camp de la EvoDevo és entendre l’impacte de la pèrdua gènica en l’evolució dels mecanismes del desenvolupament animal considerant diferents escenaris evolutius. En escenaris de selecció positiva, la pèrdua hauria comportat canvis morfològics o fisiològics que haurien permès l’adaptació de les espècies a noves condicions ambientals. En escen

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20

Boisvert, Catherine Anne. "The Origin of Tetrapod Limbs and Girdles: Fossil and Developmental Evidence." Doctoral thesis, Uppsala universitet, Evolutionär organismbiologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-98911.

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Around 375 million years ago, the first tetrapods appeared, marking one of the most important events in vertebrate evolutionary history. The fin to limb transition saw the appearance of fingers and a weight bearing pelvic girdle. While very little research has been done on the evolution of the tetrapod pelvic girdle, a fair amount has been done on the origins of fingers but some aspects remained controversial. A combination of palaeontology, developmental biology and comparative morphology was therefore used in this thesis to better understand the fin to limb transition. The pectoral fin of Pa

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21

Hebeisen, Michaël. "From cells to organs: the developmental challenge of multicellular organisms." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32382.

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During the development of a multicellular organism, the cell cycle must be tightly regulated in order to ensure that cell division and growth are coordinated with the ongoing cell fate specification and morphogenetic programs. Although the molecular mechanisms that drive cell division are well understood, many of the signaling pathways regulating their functions during development remain to be discovered. The nematode Caenorhabditis elegans represents a unique model system to investigate developmental reg

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22

Gayet, Arnaud. "Development of new chiral bicyclic ligands : applications in catalytic asymmetric transfer hydrogenations, epoxidations, and epoxide rearrangements /." Uppsala : Acta Universitatis Upsaliensis: Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4753.

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23

Karamollaoglu, Irem. "Development Of Qcm Based Dna Biosensors For Detection Of Genetically Modified Organisms." Phd thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/3/12608288/index.pdf.

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A great effort has been recently devoted to the development of new devices for the detection of specific sequences of DNA, due to increasing need of label - free, fast, cheap, and miniaturized analytical systems able to detect target sequences for screening purposes, especially in food industry for genetically modified organisms (GMOs). In this study, development of a QCM - based DNA biosensor for the detection of the hybridisation of CaMV 35S promoter sequence (P35S) was investigated. Attention was focused on the choice of the coating chemistry that could be used for the immobilisation of p

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24

Hutchison, Luke A. D. (Luke Alexander Daysh) 1976. "Whole-organism integrative expressome for C. elegans enables in silico study of developmental regulation." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/66005.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 117-119).<br>The C. elegans nematode has been extensively studied as a model organism since the 1970s, and is the only organism for which the complete cell division tree and the genome are both available. These two datasets were integrated with a number of other datasets available at WormBase.org, such as the anatomy ontology, gene expression profiles extracted from 8ooo peer-reviewed papers, and

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25

Ward, Laura Chloe. "Cell and tissue interactions organise apico-basal polarity during zebrafish neural tube development." Thesis, King's College London (University of London), 2014. https://kclpure.kcl.ac.uk/portal/en/theses/cell-and-tissue-interactions-organise-apicobasal-polarity-during-zebrafish-neural-tube-development(ef0173de-2a7f-4d0e-9bc7-bbca28c26f9d).html.

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Much of our current knowledge of cell polarisation is based on single cells or cultured cellular aggregates in a stable environment, which does not fully recapitulate the complex dynamics of embryonic development. This thesis uses the developing brain of the transparent zebrafish embryo as a model in which to examine polarisation strategies during morphogenesis in vivo. Zebrafish neurulation involves the transformation of an initially solid primordium into an epithelial tube. Prior to this, neural progenitor cells must acquire apico-basal polarity through assembly of apical complexes at the ti

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26

Emma, Marco Giuseppe <1990&gt. "Development of new Protocols for Organocatalysis." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amsdottorato.unibo.it/8641/1/Marco%20Giuseppe%20Emma%20-%20Development%20of%20new%20protocols%20for%20organocatalysis%20.pdf.

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In this work the development of new organocatalytic protocols is reported. After a brief introduction on Organocatalysis in Chapter 1, The study of a sustainable Direct Enantioselective Proline-catalysed aldol reaction is described in Chapter 2. The organocatalysed alpha-fluorination of chiral gamma nitroaldehydes is studied in Chapter 3. Finally, the functionalization of nanomaterials for organocatalytic application is described in Chapter 4.

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27

Taylor, Andrew. "Experimenting with self-organised learning for organisational growth : a person-centred approach." Thesis, Brunel University, 1997. http://bura.brunel.ac.uk/handle/2438/5531.

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This thesis records my professional search for a management model which will harness the fill capabilities of people in organisations to the achievement of the organisations, goals. This search has taken place in the context of the lost Office in which I have spent my working life. The key event in this search was my introduction to Self-Organised Learning (S-O-L) in 1984, during the Centre for the Study of Human Learning's S-O-L action research project on supervisory and managerial effectiveness. My survey of the literature in the fields of management, learning and psychology has prompted me

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Guiteras, Capdevila Montserrat <1980&gt. "Development of Organocatalytic stereoselective SN1 type reactions." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4370/1/Guitera_Capdevila_Montse_tesi.pdf.

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The proposal in my thesis has been the study of Stereoselective α-alkylation through SN1 type reaction. SN1 type reaction involves a stabilized and reactive carbocation intermediate By taking advantages of stability of particular carbocations, the use of carbocations in selective reactions has been important. In this work has been necessary to know the stability and reactivity of carbocations. And the work of Mayr group has helped to rationalize the behaviour and reactivity between the carbocations and nucleophiles by the use of Mayr’s scale of reactivity. The use of alcohols to performed th

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Guiteras, Capdevila Montserrat <1980&gt. "Development of Organocatalytic stereoselective SN1 type reactions." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4370/.

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The proposal in my thesis has been the study of Stereoselective α-alkylation through SN1 type reaction. SN1 type reaction involves a stabilized and reactive carbocation intermediate By taking advantages of stability of particular carbocations, the use of carbocations in selective reactions has been important. In this work has been necessary to know the stability and reactivity of carbocations. And the work of Mayr group has helped to rationalize the behaviour and reactivity between the carbocations and nucleophiles by the use of Mayr’s scale of reactivity. The use of alcohols to performed th

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30

Erdélyi, Máté. "Towards the Development of Photoswitchable β-Hairpin Mimetics". Doctoral thesis, Uppsala universitet, Avdelningen för organisk kemi, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4057.

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Peptide secondary structure mimetics are important tools in medicinal chemistry, as they provide analogues of endogeneous peptides with new physicochemical and pharmacological properties. The β-hairpin motif has been shown to be involved in numerous physiological processes, among others in regulation of eucariotic gene transcription. This thesis addresses the design, synthesis and conformational analysis of photoswitchable β-hairpin mimetics. The developmental work included the establishment of an improved procedure for cross coupling of aryl halides with terminal alkynes. Microwave mediated S

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31

Fukushima, Tomohiko. "Ecological characteristics of deep-sea benthic organisms in relation to manganese nodules development practices." 京都大学 (Kyoto University), 2004. http://hdl.handle.net/2433/145471.

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32

Selander, Nicklas. "Development of Multi-Component Reactions using Catalytically Generated Allyl Metal Reagents." Licentiate thesis, Stockholm University, Department of Organic Chemistry, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8077.

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<p>This licentiate thesis is based on the development of catalytic reactions for the synthesis and application of organometallic reagents. By use of palladium pincer-complex catalysts, we have developed an efficient procedure for the synthesis of allylboronates starting from allylic alcohols. These reactions were further extended by including various one-pot multi-component reactions, using the in situ generated allylboronates. Furthermore, novel unsymmetrical palladium pincer-complexes were synthesized and studied in auto-tandem catalysis.</p>

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33

Bertuzzi, Giulio <1991&gt. "Novel Asymmetric Organocatalytic Transformations: Development, Optimization and Transformations." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amsdottorato.unibo.it/9003/1/PhD_dissertation_Giulio_Bertuzzi.pdf.

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The developement of novel organocatalytic transformations is described. The elaborate mainly focuses on two catheories of organic reactions, namely azinium cations functionalizations (dearomatizations and aromatic subsititutions) and higher order cycloadditions. Particular attention has been devoted at the study and optimization of the reaction conditions and catalyst structure, in order to maximize yield and enantiopurity of the products as well as minimizing the catalyst loading and using the mildest conditions. The substrate scope of asymmetric reactions has always been thoroughly investiga

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34

Robson, Michael H. "Sorption studies of oligonucleotide DNA on montmorillonite clay : development of an improved assay protocol /." View online, 2009. http://ecommons.txstate.edu/bchemtad/6.

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Thesis (M.S.)--Texas State University--San Marcos, 2009.<br>Vita. Reproduction permission applies to print copy: Blanket permission granted per author to reproduce. Includes bibliographical references (leaves 68-70).

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35

Walsh, Patrick Thomas. "The plasticity of life histories during larval development and metamorphosis, using amphibians as study organisms." Thesis, University of Glasgow, 2008. http://theses.gla.ac.uk/183/.

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The ability of animals to vary growth, development rate and behaviour in response to environmental conditions has been well documented, particularly during the larval phase in animals with complex life cycles. The evolution and maintenance of plasticity in response to environmental conditions is likely to be adaptive in animals that face unpredictable environments. However, there are two aspects of life histories in animals with complex life cycles, which would be expected to favour plasticity, that have received limited attention: traits during metamorphic climax and variation in the life his

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Bologna, Fabio <1992&gt. "Development of reverse docking protocols for virtual screening in nanomedicine." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9932/1/bologna_fabio_tesi.pdf.

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One of the first computational chemistry tools that have been used in pharmaceutical research is molecular docking, which infers the interaction between two molecules, usually a small active compound and a receptor, on the basis of their 3D structures. During my three years of PhD studies I worked mainly on re-purposing molecular docking tools to investigate the interactions between a single molecule of interest and a collection of proteins of pharmacological interest. Since this process is essentially the inverse of what is usually done in pharmaceutical research, the technique is called reve

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37

Martinez, Bautista Naim. "Transgenerational Responses to Environmental Stressors in Vertebrates: From Organisms to Molecules." Thesis, University of North Texas, 2019. https://digital.library.unt.edu/ark:/67531/metadc1609067/.

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Genomic modifications occur slowly across generations, whereas short-term epigenetic transgenerational inheritance of adaptive phenotypes may be immediately beneficial to large numbers of individuals, acting as a bridge for survival when adverse environments occur. In this study we used dietary exposure to crude oil as an example of an environmental stressor to assess its effects from the molecular to the organismal levels in piscine and avian animal models. In addition, we assessed the role of the parental exposures on their offspring F1 generation. The research developed in this dissertation

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Vinelli, Alessandra <1982&gt. "Development of bionanotechnological strategies for signal enhancement in nucleic acids biosensors." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3751/1/vinelli_alessandra_tesi.pdf.

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Nucleic acid biosensors represent a powerful tool for clinical and environmental pathogens detection. For applications such as point-of-care biosensing, it is fundamental to develop sensors that should be automatic, inexpensive, portable and require a professional skill of the user that should be as low as possible. With the goal of determining the presence of pathogens when present in very small amount, such as for the screening of pathogens in drinking water, an amplification step must be implemented. Often this type of determinations should be performed with simple, automatic and inexpensiv

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Vinelli, Alessandra <1982&gt. "Development of bionanotechnological strategies for signal enhancement in nucleic acids biosensors." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3751/.

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Nucleic acid biosensors represent a powerful tool for clinical and environmental pathogens detection. For applications such as point-of-care biosensing, it is fundamental to develop sensors that should be automatic, inexpensive, portable and require a professional skill of the user that should be as low as possible. With the goal of determining the presence of pathogens when present in very small amount, such as for the screening of pathogens in drinking water, an amplification step must be implemented. Often this type of determinations should be performed with simple, automatic and inexpensiv

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40

Agmon, Eran. "The foundation of agency| An exploration of how minimal organisms emerge from and adapt to their environments." Thesis, Indiana University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10149600.

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<p> Agents are of central importance to cognitive science, but research usually takes them as pre-given and proceeds to study some of their particular aspects, often without awareness of or a definite answer to the question, “what is an agent?” The conceptual framework of autopoiesis and enaction provides a foundation that defines agents as emergent individuals that act in an environment to fulfill their physiological needs. </p><p> To establish this definition in concrete examples, this dissertation introduces computational models and analyses that demonstrate several propertie

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41

Kuchen, Erika. "How organs organise their ontogeny : modelling feedback between polarity, growth and geometry during Arabidopsis leaf development." Thesis, University of East Anglia, 2011. https://ueaeprints.uea.ac.uk/38820/.

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Ayers, Emily Mitchell. "Pedogenesis in rain Gardens the role of earthworms and other organisms in long-term soil development /." College Park, Md.: University of Maryland, 2009. http://hdl.handle.net/1903/9178.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2009.<br>Thesis research directed by: Dept. of Biological Resources Engineering. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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Curthoys, Mark. "Trade union legislation 1871-6 : government responses to the development of organised labour." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302855.

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44

John, Koodathinal John. "A Biblical model for personnel development and conflict resolution in an organised ministry." Online full text .pdf document, available to Fuller patrons only, 2002. http://www.tren.com.

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Bragato, Nicola <1995&gt. "Development of Organocatalysts for the Synthesis of Heterocyclic Compounds through CO2 Insertion Reactions." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19017.

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A series of novel Ionic Liquids (ILs) consisting of tetraalkyl-phosphonium or ammonium cations and phenol or polyhydroxybenzene counteranions were synthesized following a metal- and halogen-free methodology previously reported by our group. The IL synthetic methodology included two steps: an initial trialkylamine or trialkylphosphine quaternization step using dimethylcarbonate (DMC) as the methylating agent, obtaining the corresponding trialkylmethyl-phosphonium or ammonium methylcarbonate ILs. Methylcarbonate ILs underwent metathesis reaction in presence of acidic counteranions precursors (e.

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Troese, Matthew. "APPROACHES TO IDENTIFY SURFACE PROTEINS OF ANAPLASMA PHAGOCYTOPHILUM DENSE-CORED ORGANISMS AS ADHESINS TO HUMAN P-SELECTIN GLYCOPROTEIN LIGAND-1." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/162.

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Anaplasma phagocytophilum is an obligatory intracellular bacterium that infects neutrophils to cause human granulocytic anaplasmosis. Sialyl Lewis x (sLex)-modified P-selectin glycoprotein ligand-1 (PSGL-1) is the confirmed receptor utilized by A. phagocytophilum to bind and invade human neutrophils and myeloid cell lines. As an obligate intracellular pathogen, the binding of A. phagocytophilum to a host cell receptor is a prerequisite step for entry and replication, and thus its survival. However, the bacterial adhesins mediating this process have yet to be identified. In this study, we s

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Corbisiero, Dario <1990&gt. "Multifarious tumor-oriented small molecules: development of synthetic methodologies and application for diagnostic platforms." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9822/3/Corbisiero_Dario_Tesi.pdf.

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Cancer represents one of the most relevant and widespread diseases in the modern age. In this context, integrin receptors are important for the interactions of cells with extracellular matrix and for the development of both inflammation and carcinogenic phenomena. There are many tricks to improve the bioactivity and receptor selectivity of exogenous ligands; one of these is to integrate the amino acid sequence into a cyclic peptide to restrict its conformational space. Another approach is to develop small peptidomimetic molecules in order to enhance the molecular stability and open the way to

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Henriksson, Emma, and Martin Holm. "Kvantitativ analys av organiska syror i kylvätska." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-13499.

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Volvo Cars är ett välkänt företag som säljer bilar över hela världen. Idag skickar Volvo Cars sin kylvätska till leverantörer för analys. Processen är komplicerad och tar mycket tid. Det finns ett intresse hos Volvo Cars att själva kunna analysera kylvätskan. För att kunna göra detta krävs det att en metod som de kan använda för att analysera kylvätskan utvecklas. Examensarbetet syftar till att utveckla en metod som gör det möjligt att analysera koncentrationen av organiska syror i Volvos kylvätska. Analysen ska göras med hjälp av en High Performance Liquid Chromatography - HPLC. De organiska

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Atienzar, Franck Andre. "Development of the random amplified polymorphic DNA (RAPD) technique to measure the effects of genotoxinsin aquatic organisms." Thesis, University of Plymouth, 2000. http://hdl.handle.net/10026.1/1757.

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Studies were undertaken to evaluate the potential of random amplified polymorphic DNA (RAPD) to detect DNA effects (including DNA damage and mutations) in aquatic invertebrates, following their exposure to a variety of environmental contaminants under laboratory conditions. After rigorous optimisation of the RAPD method, the protocol, which used a high annealing temperature (50"C for 10-mer primers), was found to generate good-quality DNA profiles from groups of organisms belonging to the bacterial, plant and animal kingdoms. The RAPD method was initially used to detect benzo(a)pyrene [B(

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Koepff, Joachim Verfasser], Marco [Akademischer Betreuer] [Oldiges, and Lars Mathias [Akademischer Betreuer] Blank. "Establishment and application of accelerated bioprocess development for filamentous organisms / Joachim Koepff ; Marco Oldiges, Lars M. Blank." Aachen : Universitätsbibliothek der RWTH Aachen, 2021. http://d-nb.info/1239566581/34.

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