Relevant bibliographies by topics / Dihydroxypyrimidine

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Dihydroxypyrimidine'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Dihydroxypyrimidine"

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Kufelnicki, Aleksander, Jan Jaszczak, Urszula Kalinowska-Lis, Cecylia Wardak, and Justyn Ochocki. "Complexes of Uracil (2,4-Dihydroxypyrimidine) Derivatives." Journal of Solution Chemistry 35, no. 5 (2006): 739–51. http://dx.doi.org/10.1007/s10953-006-9017-1.

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Powdrill, Megan H., Jerome Deval, Frank Narjes, Raffaele De Francesco, and Matthias Götte. "Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines." Antimicrobial Agents and Chemotherapy 54, no. 3 (2009): 977–83. http://dx.doi.org/10.1128/aac.01216-09.

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ABSTRACT We studied the biochemical mechanisms associated with inhibition and resistance to a 4,5-dihydroxypyrimidine carboxylate that inhibits the hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B. On the basis of the structure of the pharmacophore, it has been suggested that these compounds may act as pyrophosphate (PPi) mimics. We monitored nucleotide incorporation events during the elongation phase and showed that the polymerase activity of wild-type NS5B was inhibited by the dihydroxypyrimidine at a 50% inhibitory concentration (IC50) of 0.73 μM. Enzymes with the G152E or P156L mu
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Shi, Daqing, Lihui Niu, and Qiya Zhuang. "Clean synthesis of pyrido[2,3-d]pyrimidines in aqueous media." Journal of Chemical Research 2005, no. 10 (2005): 648–50. http://dx.doi.org/10.3184/030823405774663048.

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The reaction of substituted cinnamonitriles and 4-amino-2,6-dihydroxypyrimidine or 2,4-diamino-6-hydroxypyrimidine in water in the presence of triethylbenzylammonium chloride (TEBA) as catalyst affords a clean synthesis of pyrido[2,3-d]pyrimidine derivatives.
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Rostkowska, Hanna, Anna Luchowska, Leszek Lapinski, and Maciej J. Nowak. "Photochemical transformations of 4,6-dihydroxypyrimidine and 2-methyl-4,6-dihydroxypyrimidine isolated in low-temperature Ar, Ne and H2 matrices." Chemical Physics Letters 745 (April 2020): 137263. http://dx.doi.org/10.1016/j.cplett.2020.137263.

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Vu, Tuan Q., Nikolai V. Yudin, Alexander A. Kushtaev, Thanh X. Nguyen, and Sergey A. Maltsev. "Spectroscopic Study of the Basicity of 4,6-Dihydroxypyrimidine Derivatives." ACS Omega 6, no. 22 (2021): 14154–63. http://dx.doi.org/10.1021/acsomega.1c00671.

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Kapoor, Bharat, EzzedinA Luhishi, AndrewKK Chung, and JakobusC Pauw. "Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency." Indian Journal of Ophthalmology 56, no. 4 (2008): 336. http://dx.doi.org/10.4103/0301-4738.41422.

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Malancona, Savina, Mattia Mori, Paola Fezzardi, et al. "5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein." ACS Medicinal Chemistry Letters 11, no. 5 (2020): 766–72. http://dx.doi.org/10.1021/acsmedchemlett.9b00608.

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Boyd, Vincent A., John Mason, Parimala Hanumesh, Jeanine Price, Charles J. Russell, and Thomas R. Webb. "2-Substituted-4,5-Dihydroxypyrimidine-6-Carboxamide Antiviral Targeted Libraries." Journal of Combinatorial Chemistry 11, no. 6 (2009): 1100–1104. http://dx.doi.org/10.1021/cc900111u.

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Keerthi Kumar, Chinnagiri T., Jathi Keshavayya, Tantry N. Rajesh, Sanehalli K. Peethambar, and Angadi R. Shoukat Ali. "Synthesis, Characterization, and Biological Activity of 5-Phenyl-1,3,4-thiadiazole-2-amine Incorporated Azo Dye Derivatives." Organic Chemistry International 2013 (August 18, 2013): 1–7. http://dx.doi.org/10.1155/2013/370626.

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5-Phenyl-1,3,4-thiadiazole-2-amine has been synthesized by single step reaction. A series of heterocyclic azodyes were synthesized by diazotisation of 5-phenyl-1,3,4-thiadiazole-2-amine by nitrosyl sulphuric acid followed by coupling with different coupling compounds such as 8-hydroxyquinoline, 2,6-diaminopyridine, 2-naphthol, N,N-dimethyl aniline, resorcinol, and 4,6-dihydroxypyrimidine. The dyes were characterized by UV-Vis, IR, 1H-NMR, 13C NMR, and elemental analysis. The synthesized compounds were also screened for biological activity.
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Tang, Jing, Kasthuraiah Maddali, Yves Pommier, Yuk Y. Sham, and Zhengqiang Wang. "Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited." Bioorganic & Medicinal Chemistry Letters 20, no. 11 (2010): 3275–79. http://dx.doi.org/10.1016/j.bmcl.2010.04.048.

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Dissertations / Theses on the topic "Dihydroxypyrimidine"

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Garlatti, Laura. "Development of Bunyavirales endonucleases inhibitors by in situ click chemistry." Electronic Thesis or Diss., Aix-Marseille, 2022. http://www.theses.fr/2022AIXM0586.

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Les virus de l'ordre des Bunyavirales constituent un problème de santé publique en raison du manque d’options thérapeutiques et de leur répartition mondiale. La protéine L gouvernant le système de réplication virale possède une activité endonucléase responsable du mécanisme du vol-de-coiffe permettant la transcription. Cette enzyme clé a été identifiée comme une cible thérapeutique de choix pour développer des antiviraux. Son mécanisme d’hydrolyse de l’ARN médié par les ions Mg2+ permet de développer des inhibiteurs chélateurs de métaux de type dicéto-acide (DCA). La synthèse guidée par la cib
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Chen, Hui-Fang, and 陳惠芳. "Self-Assembly of dihydroxypyrimidine-based Metal Complexes." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/40715693163039617195.

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碩士<br>中國文化大學<br>應用化學研究所<br>95<br>Abstract This thesis focuses on the preparation of novel-based metal-organic frameworks based on nucleobases via self-assembly strategy and the study of the influence of pH-values and alkali hydroxide (NaOH, KOH, CsOH). We chosen two uracil-derivatives 4,6-dihydroxypyrimidine (dhp-H2) and 2,4-dihydroxypyrimidine-5-carboxylic acid (H3L1), and 2-methyl-1H-benzo[d]imidazole-5-carboxylic acid (H2L2), as potential organic ligands. At first, assembly of Ni2+, Co2+or Zn2+ ions with dhp-H2 in water or alcohol at ambient temperature led to the formation of
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Chen, Han-Yin, and 陳函听. "Self-assembly, Structures, and Properties of Coordination Compounds Based on Dihydroxypyrimidine." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/psfr2d.

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碩士<br>國立臺北科技大學<br>化學工程研究所<br>101<br>This thesis focuses on the preparation of based metal–organic frameworks based on nucleobases via a self-assembly strategy. Two uracil-derivatives, 4,6-dihydroxypyrimidine (H2dhp) and 2,4-dihydroxypyrimidine-5-carboxylic acid (H3dhpca), were selected for use as potential organic ligands. The assembly of CaII, NiII ions with 4,6-dihydroxypyrimidine (H2dhp) in water or alcohol at ambient temperature led to the formation of the discrete molecule [Ni(Hdhp)2(H2O)4] (1) and a 2D metal–organic frameworks {[Ca(Hdhp)2(H2O2)]•THF}n (2). When MnII, MgII and ZnII were r
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Book chapters on the topic "Dihydroxypyrimidine"

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Ishikawa, T. "From 5-Amino-2,6-dihydroxypyrimidine-4-carboxylic Acid." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-01777.

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Conference papers on the topic "Dihydroxypyrimidine"

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Vu, Tuan, Xuan Nguyen, Nikolai Yudin, and Alexander Kushtaev. "KINETICS AND NITRATION MECHANISM OF 4,6-DIHYDROXYPYRIMIDINE AND ITS DERIVATIVES IN THE PRESENCE OF NITROUS ACID." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m752.aks-2019/199-205.

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You might also be interested in the extended bibliographies on the topic 'Dihydroxypyrimidine' for particular source types:
Journal articles
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