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Dissertations / Theses on the topic 'Dole effect'

Author: Grafiati
Published: 25 May 2024
Last updated: 31 July 2025

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1

Paul, Clémence. "Fractionnement du dioxygène lors des processus biologiques : application à la reconstruction de la productivité passée de la biosphère." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASJ002.

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La composition isotopique du dioxygène piégé dans les bulles d'air des carottes de glace peut être utilisée pour reconstituer la productivité globale de la biosphère dans le passé ainsi que pour documenter l'évolution du cycle de l'eau aux basses latitudes. Le travail de cette thèse a été d'améliorer l'interprétation du δ18O de l'O2. Pour cela, nous avons affiné la détermination des différents coefficients de fractionnement associés au cycle de l'oxygène au niveau de la biosphère terrestre, c'est-à-dire pendant les processus de respiration et de photosynthèse. Afin de quantifier ces coefficien
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2

Alfvén, Tobias. "Bone and kidney effects from cadmium exposure : dose effect and dose response relationships /." Stockholm : Karolinska Univ. Press, 2002. http://diss.kib.ki.se/2002/91-7349-341-4.

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3

Kafrouni, Marilyne. "Relation dose-effet et optimisation de la dosimétrie en radiothérapie interne sélective du carcinome hépatocellulaire." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTT007/document.

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La radiothérapie interne sélective (RTIS), en plein développement ces dernières années, constitue une alternative thérapeutique pour les cancers primaires et secondaires inopérables du foie. Le principe repose sur l’administration intra-artérielle de microsphères chargées d’yttrium-90 avec pour objectif la destruction des cellules tumorales par l’irradiation.L’activité d’yttrium-90 à administrer au patient est actuellement généralement prescrite à partir d’approches semi-empiriques ou peu personnalisées, faciles à mettre en place cliniquement. De nouveaux outils sont aujourd'hui disponibles se
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4

Rostand, Neil. "Modélisation compacte de l'effet des radiations naturelles des dispositifs sub-28nm pour des applications automobiles et aéronautiques." Thesis, Toulouse, ISAE, 2019. http://www.theses.fr/2019ESAE0035.

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L’objectif de cette thèse était le développement de modèles SET (Single Event Transient) et TID (Total Ionizing Dose) pour les MOSFETs de technologies fortement intégrées, reposant notamment sur la technologie SOI. Ces modèles devaient respecter les standards de la modélisation compacte afin d’assurer leur utilisation dans les simulateurs de circuits SPICE (ELDO, SPECTRE, PSPICE …) tout en assurant la justesse du contenu physique. Le langage d’implémentation est alors le Verilog-A. En 1A, l’investigation physique des SET a été effectuée à l’aide de simulations TCAD. Cette tâche a supporté le d
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Morency, Catherine-Ève. "Effets de l'estradiol et de la progestérone sur le contrôle respiratoire en situation hypoxique chez le raton nouveau-né et impacts à long terme." Thesis, Université Laval, 2006. http://www.theses.ulaval.ca/2006/23851/23851.pdf.

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6

Sutton, Akil K. "Displacement Damage and Ionization Effects in Advanced Silicon-Germanium Heterojunction Bipolar Transistors." Thesis, Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/7217.

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A summary of total dose effects observe in advanced Silicon Germanium (SiGe) Heterojunction Bipolar Transistors (HBTs) is presented in this work. The principal driving froces behin the increased use of SiGe BiCMOS technology in space based electronics systems are outlined in the motivation Section of Chapter I. This is followed by a discussion of the strained layer Si/SiGe material structure and relevant fabrication techniques used in the development of the first generation of this technology. A comprehensive description of the device performance is presented. Chapter II presents an overview
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7

Rossouw, Maria Susanna. "Validation of endpoints as biomarkers of low-dose radiation damage." Thesis, Cape Technikon, 2004. http://hdl.handle.net/20.500.11838/1461.

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Thesis (MTech (Biomedical Technology))--Cape Technikon, Cape Town, 2004<br>The need for radiobiological research was bom from the discovery that high doses of radiation could cause cancer and other health effects. However, recent developments in molecular biology uncovered the effects of low doses of radiation on different biological systems and as a result new techniques have been developed to measure these effects. The aim of this study was thus to validate biomarkers of initial DNA strand breaks, micronucleus formation, and the different pt ;ases of apoptosis as biological indic
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Ferraro, Rudy. "Development of Test Methods for the Qualification of Electronic Components and Systems Adapted to High-Energy Accelerator Radiation Environments." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTS118.

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Le Grand collisionneur de hadrons (LHC), le plus grand et le plus puissant au monde, a démarré en 2008 et constitue la dernière étape du complexe des accélérateurs du CERN. Le LHC consiste en un anneau de 27 kilomètres d'aimants supraconducteurs permettant d'accélérer deux faisceaux jusqu'à 7 TeV avant de les faire entrer en collision à 14 TeV dans l'une des cinq expériences de contrôle du résultat de la collision. Le LHC a notamment permis la découverte du boson de Higgs et d'autres particules baryoniques prédites par le modèle standard. L'environnement de rayonnement du LHC et de ses lignes
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9

Erekson, David McConkie. "Scheduled Healing: The Relationship Between Session Frequency and Psychotherapy Outcome in a Naturalistic Setting." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/4037.

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The dose-effect relationship in psychotherapy has been examined extensively, but few studies have included session frequency as a component of psychotherapy "dose." Those studies that have examined the effects of session frequency have indicated that it may affect both the total amount of recovery and the speed of recovery. No studies were found examining the clinical significance of this construct in a naturalistic setting. The change trajectories of 16,003 clients were examined using multi-level modeling and including session frequency as a fixed effect. Of these clients, subgroups were ide
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10

Jaillet, Cyprien. "Modifications du glycome endothélial vasculaire dans le contexte d'une irradiation à forte dose." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066021/document.

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La radiothérapie constitue l’un des principaux traitements pour l’éradication des cancers. Cependant, elle présente un risque d’effets secondaires aux tissus sains environnant la tumeur. Dans ce processus, le système vasculaire et plus particulièrement l’endothélium jouent un rôle clé. Les cellules endothéliales activées favorisent le recrutement chronique des thrombocytes et des leucocytes, contribuant ainsi aux effets secondaires. D’autre part, dans les maladies inflammatoires, les glycanes exprimés à la surface des cellules endothéliales sont modifiés et influencent le recrutement des cellu
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11

Brucoli, Matteo. "Total ionizing dose monitoring for mixed field environments." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTS093/document.

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La mesure de la dose ionisante est aujourd'hui une tâche cruciale pour une large gamme d'applications fonctionnant dans des environnements de rayonnement sévères. Dans le contexte de l'amélioration de la luminosité du grand collisionneur de hadrons (LHC), la mesure des niveaux de rayonnement le long du complexe d'accélérateurs du CERN va devenir encore plus difficile. A cet effet, une connaissance plus détaillée du champ de rayonnement dans le tunnel de l'accélérateur et ses zones adjacentes devient nécessaire pour définir les exigences d'installation, de déplacement ou de blindage de l'électr
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Aguirre, Fernando Rodrigues. "Estudo sobre distribuição de cargas em semicondutores sujeitos a radiação ionizante." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-13032017-113040/.

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Os efeitos da radiação ionizante em dispositivos eletrônicos é uma preocupação crescente na tecnologia de semicondutores, especialmente devido à contínua redução dos dispositivos e ainda maior, quando são destinados para uso em ambientes agressivos com alta radiação, tais como missões espaciais, aceleradores de partículas ou reatores nucleares. Dentre os vários efeitos causados pela radiação ionizante em dispositivos eletrônicos está aquele devido à Dose Acumulada (Total Ionizing Dose - TID), o qual a acumulação de danos de radiação no dispositivo muda seu funcionamento normal. O TID causado p
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13

Foo, Kerwyn Yi Min. "Methodological uncertainties in radiotherapy dose-effect analysis." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/24421.

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Cancer and normal tissues in patient populations exhibit variability in biological response to the same dose of radiation. Sources of this variability include: • Inherent biological factors of patient, tumour or tissue • Metrics to measure, classify or declare biological outcomes • Volumetric (prescription of target or avoidance regions) • Dosimetric and delivery Dosimetric and delivery variation is easily measured and has relatively little impact on variation of outcome in modelling studies. Volumetric variation contributes greatly to uncertainty, dependent on human judgement by oncologi
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14

Dalloneau, Emilie. "Idendification de gènes à effet de dose impliqués dans la pathophysiologie des aneuploïdies associées au chromosome 21." Phd thesis, Université d'Orléans, 2010. http://tel.archives-ouvertes.fr/tel-00688939.

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Une variation du nombre de copies des gènes du chromosome 21 humain (HSA21) entraine des anomalies morphologiques et physiologiques d'un grand nombre d'organes chez les patients. La Trisomie 21, ou syndrome de Down et les monosomies partielles du HSA21 conduisent à des phénotypes complexes et variables. Afin d'identifier les gènes du HSA21 sensibles aux effets de dose, nous avons développé le modèle de monosomie Ms1Yah, pour la région Prmt2-Col6a1 du chromosome murin 10 (MMU10). L'analyse de ce modèle a montré que les souris Ms1Yah développent une altération des réponses inflammatoire et pulmo
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15

Zerabruk, MA. "Repair of sub-lethal damage following single and split-dose irradiation using 60co-gamma and p(66)Be neutrons." Thesis, Cape Peninsula University of Technology, 2005. http://hdl.handle.net/20.500.11838/1504.

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Thesis (MTech Biomedical Technology)--Cape Peninsula University of Cape Town, 2005<br>In clinical radiotherapy, experiments are performed to determine optimal conditions of the radiation prior to radiotherapy. These experiments focus on the relative biological effectivness(RBE) determination and are predominantly applied in high linear energy transfer (LET) radiations i.e. fast neutrons, as the RBE values for such radiations vary greatly. In general, the RBE of a certain radiation relative to a given reference radiation flCo gamma) varies widely with the energy, dose, dose rate, frac
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16

Eiden, Céline. "Essai de faisabilité du suivi thérapeutique pharmacologique et de l'optimisation des antifongiques azolés récents : voriconazole et posaconazole." Montpellier 1, 2009. http://www.theses.fr/2009MON13508.

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Le voriconazole (VCZ) et le posaconazole (PCZ) sont des antifongiques récents à structure triazolée. Après avoir rapporté un cas d'allongement de l'espace QT avec torsade de pointes, suivi d'un arrêt cardiaque sous VCZ, nous avons effectué une étude sur l'ensemble des cas d'effets indésirables notifiés dans la Base Nationale de Pharmacovigilance et analysé les cas rapportés dans la littérature. Ces données nous ont permis de préciser les circonstances d'apparition des effets indésirables du VCZ. Nous avons ensuite mis au point et validé une méthode de dosage par chromatographie liquide haute p
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17

McDonald-Morken, Colleen Ann. "Hawk and Dove Stress Response Profiles in Humans." Thesis, North Dakota State University, 2011. https://hdl.handle.net/10365/29861.

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A recent evolutionary theory hypothesizes that there are two primary biobehavioral profiles of stress responding. Labeled "hawk" and "dove," each is characterized by divergent patterns of autonomic nervous system and neuroendocrine system activations in response to stress as well as distinct affective and behavioral tendencies. These profiles are prominent in a number of species, and it has been hypothesized that hawk-like and dovelike responses to stress may, in part, explain variability in stress-related health outcomes. This study is a preliminary investigation of hawk and dove biobehaviora
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18

Vaccarino, Anthony Leonard. "Naloxone analgesia in BALBc mice : a dose-dependent relationship." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66239.

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19

Platt, Gerald D. "Wind effects on a hemispherical dome." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/101360.

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A review of the past wind tunnel experiments involving the measurement of pressures over the surface of a hemispherical dome is made, and the flow parameters of these experiments are compared. A hemispherical dome is subjected to a flow in the open-throat wind tunnel at VPI&SU, and the resulting pressure measurements are given. An experiment utilizing the 6-ft square stability wind tunnel at VPI&SU to measure the pressures over the surface of a hemispherical dome is organized but not conducted. ABAQUS, a nonlinear finite element program, is used to analyze a hemispherical, lamella dome subje
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20

Takam, Rungdham. "Determination of dose distribution of Ruthenium-106 Ophthalmic applicators." Title page, contents and abstract only, 2003. http://web4.library.adelaide.edu.au/theses/09SM/09smt1363.pdf.

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"August 2003" Bibliography: leaves 108-117. 1. Ruthenium-106 ophthalmic applicators -- 2. General principle of thermoluminescent dosimeter -- 3. Study of basic characteristics of CaSO4:Dy TLD -- 4. Measurements of COB and CCA type ruthenium-106 ophthalmic applicator dose distributions -- 5. Determination of the dose rate distribution using a MOSFET detector -- 6. Summary and conclusion. In this project, small CaSO4:Dy TLDs and a semiconductor MOSFET dosimeter were used for the determination of on-axis depth dose-rate distributions of 15-mm and 20-mm ruthenium-106 applicators in acrylic eye pha
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21

Mazzetti, Scott A. "Akt and ERK activation in human skeletal muscle : dose-dependency of responses to increasing muscle contractions." Virtual Press, 2003. http://liblink.bsu.edu/uhtbin/catkey/1259313.

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Akt activation mediates increases in glycogen synthesis in response to insulin in humans, while extracellular signal-regulated kinase (ERK) activation increases gene transcription and protein translation in response to endurance and resistance exercise. Akt activation increases only in response to intense muscle contractions and during hypertrophy in rats. No study has examined Akt and ERK activation with increasing numbers of intense muscle contractions in humans. Therefore, the primary objectives of this investigation were to determine if Akt activation increases in response to resistance ex
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22

Ludwig, Sophie. "Comportement d'un "Perturbateur Endocrinien" et d'un "non Perturbateur Endocrinien" vis à vis de la toxicité testiculaire chez le rat." Phd thesis, Université Paris Sud - Paris XI, 2011. http://tel.archives-ouvertes.fr/tel-00658641.

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Depuis plusieurs années, des agents exogènes environnementaux appelés perturbateurs endocriniens (PE), sont soupçonnés d'interférer avec les fonctions essentielles de reproduction et de développement chez de nombreux organismes vivants. Au travers de ce travail, nous avons tenté de combler certaines lacunes afin de mieux comprendre les dangers pour l'Homme posés par ces produits. Des études ont été menées visant à caractériser la toxicité testiculaire, chez le rat adulte, induite par des composés aux mécanismes d'action toxique divers (PE et non PE), ceci dans le but d'établir in fine l'existe
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Bannwarth, E. "Pancytopénie au méthotrexate à faible dose dans la polyarthrite rhumatoi͏̈de : à propos d'un cas et revue de la littérature." Bordeaux 2, 1992. http://www.theses.fr/1992BOR2M203.

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24

Egbe, Nneoyi Onen. "Measurement of dose in diagnostic radiology and the effect of dose reduction on image quality." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources. Online version available for University members only until March, 23, 2010, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25469.

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25

Verdier, Marie-Clémence. "Les bêta-lactamines : apport de l'individualisation thérapeutique par la mesure des concentrations pour les patients hospitalisés." Rennes 1, 2012. http://www.theses.fr/2012REN1B003.

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Les bêta-lactamines sont la classe d'antibiotiques la plus diversifiée et la plus utilisée dans le monde du fait de leur très large spectre et de leur bonne tolérance. Elles ne sont pas considérées comme de bonnes candidates pour le suivi thérapeutique pharmacologique (STP) car leur index thérapeutique est supposé être large. Cependant, il y a plusieurs arguments suggérant l'utilité du STP dans certaines circonstances. Chez les patients de réanimation, les altérations physiologiques peuvent modifier de façon importante la pharmacocinétique des médicaments. Par conséquent, le risque d'un traite
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26

Tangboonduangjit, Puangpen. "Intensity-modulated radiation therapy dose maps the matchline effect /." Access electronically, 2006. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20060724.095712/index.html.

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27

Hollmark, Malin. "Absorbed dose and biological effect in light ion therapy." Doctoral thesis, Stockholm : Medical Radiation Physics, Stockholm university together with KI, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7756.

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28

Davis, Kenneth Ralph 1964. "Two-dimensional simulation of the effects of total dose ionizing radiation on power-MOSFET breakdown." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277053.

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The effects of ionizing radiation on the breakdown-voltage degradation of power-MOSFET termination structures were examined through two-dimensional simulation. A wide variety of sensitivity to surface-charge density was found for various devices employing floating field rings and/or equipotential field plates. Termination structures that were both insensitive to surface charge and possessed a high breakdown voltage were identified. The results were compared with measurements made on selected structures. The principal ionizing radiation damaging mechanisms in MOS devices are discussed. Modifica
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29

Lacourt, Aude. "Mésothéliome : étiologie professionnelle à partir d’enquêtes cas-témoins françaises." Thesis, Bordeaux 2, 2010. http://www.theses.fr/2010BOR21738/document.

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Le mésothéliome pleural est considéré comme très spécifique d’une exposition à l’amiante. Cependant, certains aspects de l’étiologie de cette maladie n’ont pas encore été bien caractérisés. Les objectifs de cette étude sont : i) d’estimer la relation dose-effet entre exposition professionnelle aux fibres d’amiante et survenue de mésothéliome pleural selon différents indicateurs temporels d’exposition ; ii) d’étudier l’effet d’une exposition professionnelle aux laines minérales et aux poussières alvéolaires de silice cristalline libre sur le risque de survenue de mésothéliome pleural et iii) d’
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Yap, Madeline M. L. "A Study of Biochemical, Pharmacokinetic, Physiological and Psychomotor Variables and Ethanol Sensitivity after Low-dose Ethanol." Thesis, The University of Sydney, 1996. https://hdl.handle.net/2123/27473.

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The influence of ALDH2 and ADH2 genotype on the biochemical, physiological, psychomotor and subjective responses of Asian subjects to a challenge dose of ethanol were investigated. One hundred and ten healthy male and female subjects of fill] or partial North East Asian descent (with ancestral origins in China, Japan, Korea and Vietnam), who were living in Australia at the time of testing, were genotyped for alcohol dehydrogenase (ADHz) and aldehyde dehydrogenase (ALDHz) enzymes using a combination of the polymerase chain reaction (PCR) with restriction enzyme digestion, allele specific oligo
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Chen, Jia. "Effect of dose and dose rate on benzo[a]pyrene induced mutational spectra in human cells." Thesis, Massachusetts Institute of Technology, 1994. http://hdl.handle.net/1721.1/36941.

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Hall, Susan Claire. "The C₃H 10T1/2 mouse embryo transformation assay : the role of radiation quality and dose-rate." Thesis, Open University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279005.

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33

Raines, Katherine Elizabeth. "The effects of chronic low-dose radiation on bumblebees." Thesis, University of Stirling, 2018. http://hdl.handle.net/1893/28699.

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The consequences to wildlife of living in contaminated areas with chronic low-dose rates of radiation are still relatively unknown. Laboratory studies using acute radiation have demonstrated that invertebrates are relatively radioresistant compared to other taxa. However, there is little scientific evidence to show how chronic low dose rates affect invertebrates. This is problematic for understanding the consequences to wildlife living in highly contaminated areas and also testing assumptions made for invertebrates by the International Commission on Radiological Protection (ICRP). This thesis
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Mughal, Safeer Kamil. "The dose and dose-rate effects of paternal irradiation on transgenerational instability in mice." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/27822.

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Of the non-targeted, delayed consequences of exposure to ionising radiation, genomic instability is a particular area of concern, especially with regard to its manifestation in the non-exposed offspring of irradiated parents. However, further analysis of these effects and their implications is mainly limited by our understanding of the underlying mechanisms and the lack of reliable data for humans. As of yet, transgenerational instability has only been consistently demonstrated in animal models using high, acute doses of ionising radiation (> 1 Sv). To investigate the effects of low-dose acute
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Adkin, Dawn Anne. "The effect of pharmaceutical exipients on small intestinal transit." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260596.

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Deal, Heather Elizabeth. "In vivo effects of T suppressor molecules : specificity and dose effects." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27870.

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The suppressor circuit and it's components have been studied extensively in this laboratory and others for the past ten years. This laboratory has produced factor-secreting hybridoma cells which are analogous to first-order T suppressor cells directed against the tumor P815 . A monoclonal antibody has been raised which recognizes a common portion of suppressor cells and factors. These tools are used in this study. It had been seen that when 20 µg A10F (factor secreted by A10, the Ts1 analogue) was injected into a mouse concurrently with P815, the suppression of the mouse's immune response was
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Beaulieu, Daniel Ryan. "A Framing Analysis: The NBA's "One-And-Done"Rule." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4288.

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In 2006, the NBA introduced the "one-and-done" rule that restricted high school graduates to enter directly into the NBA draft following high school. In turn, a high school prospect would essentially now have the option of playing professionally elsewhere (most likely overseas), enter the NBA's Developmental League, or play NCAA basketball. The rule has proved to be quite controversial, as it has had a great effect on both NBA and NCAA basketball, as well as the players. Various media outlets have been quite vocal not only about the rule itself, but the perceived effects it has had on both col
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Wong, Tony Po Yin, and tony wong@swedish org. "Improving Treatment Dose Accuracy in Radiation Therapy." RMIT University. Applied Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080104.144139.

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The thesis aims to improve treatment dose accuracy in brachytherapy using a high dose rate (HDR) Ir-192 stepping source and in external beam therapy using intensity modulated radiation therapy (IMRT). For HDR brachytherapy, this has been achieved by investigating dose errors in the near field and the transit dose of the HDR brachytherapy stepping source. For IMRT, this study investigates the volume effect of detectors in the dosimetry of small fields, and the clinical implementation and dosimetric verification of a 6MV photon beam for IMRT. For the study of dose errors in the near field o
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Figueiredo, Ricardo Tajra 1984. "Manejo da adubação potássica na cultura da batata-doce /." Botucatu, 2019. http://hdl.handle.net/11449/181414.

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Orientador: Adalton Mazetti Fernades<br>Coorientador: Pablo Forlan Vargas<br>Banca: Roberto Lyra Villas Bôas<br>Banca: Fábio Rafael Echer<br>Resumo: Para a maioria das hortaliças que produzem raízes tuberosas, o potássio (K) é o nutriente mineral exigido em maior quantidade. Entretanto, a aplicação de doses elevadas desse nutriente pode prejudicar o desenvolvimento das plantas, devido ao aumento da concentração salina ou mesmo decorrer em grandes perdas por lixiviação, especialmente em solos arenosos. Desta forma, o objetivo deste trabalho foi avaliar o crescimento e a produtividade da batata-
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Skwarchuk, Mark William. "Presence of cell-cycle dependent substructure at low dose in the radiation survival response of asynchronous V79-WNRE cells." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/28950.

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Survival studies using cell sorting techniques together with data averaging on asynchronously dividing V79-WNRE cells reveal statistically significant evidence of substructure in the radiation survival response at low dose (2 to 3 Gy) that cannot be adequately characterized by a single linear-quadratic function, S = exp( -αD -βD²). The data suggest a two-component response that is particularly evident when plotted in the linear form of the linear-quadratic equation, -ln(S)/D = α + βD. Application of other survival models (Single Hit + Multi Target and Repair-Misrepair) does not eliminate the s
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Blyth, Benjamin John, and benjamin blyth@flinders edu au. "Development and use of an adoptive transfer method for detecting radiation-induced bystander effects in vivo." Flinders University. School of Medicine, 2009. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20091008.150317.

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Ionising radiation can cause damage to DNA that can result in gene mutations contributing to carcinogenesis. Radiation-protection policy currently estimates cancer risks from exposures to radiation in terms of excess risk per unit dose. At very low radiation dose-rates, where not all cells are absorbing radiation energy, this formula carries the inherent assumption that risk is limited to those cells receiving direct energy depositions. Numerous studies have now called this assumption into question. Such low dose-rates are in the relevant range that the public receives from natural background
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42

Baba, Kiichiro. "Experimental model for the irradiation-mediated abscopal effect and factors influencing this effect." Kyoto University, 2020. http://hdl.handle.net/2433/259722.

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43

Ball, Jessica Lynne. "Field and numerical investigations of lava dome hydrothermal systems and their effects on dome stability." Thesis, State University of New York at Buffalo, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3612916.

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<p> This study investigates the potential for hydrothermal alteration and circulation in lava domes using combined analytical, remote sensing and numerical modeling approaches. This has been accomplished in three parts: <i>1) </i> A comprehensive field, geochemical and remote sensing investigation was undertaken of the hydrothermal system in the Santiaguito lava dome complex in Guatemala. The Santiaguito domes were found to contain mainly hydrous silica alteration, which is unlikely to weaken dome rock, but the summit of Santa Maria was found to contain pervasive argillic alteration (clay mine
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Shintani, Takashi. "Investigation of 4D dose in volumetric modulated arc therapy-based stereotactic body radiation therapy: does fractional dose or number of arcs matter?" Kyoto University, 2020. http://hdl.handle.net/2433/253487.

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Smith, Farouk. "Total ionizing dose mitigation by means of reconfigurable FPGA computing." Thesis, Link to the online version, 2007. http://hdl.handle.net/10019/713.

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Huang, Bingsheng, and 黃炳升. "Radiation dose and cancer risk of cardiac CT scan and PET-CT scan." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B41757993.

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Chilà, Deborah. "Dose tracking in radiation oncology using daily CBCT: effects of physical parameters on dose calculation accuracy." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/20587/.

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The availability of cone beam computerized tomography (CBCT) images at the time of treatment has opened possibilities for recalculations and tracking of the delivered dose, becoming an effective tool for adaptive radiotherapy. A significant component in the accuracy of dose recalculation on CBCT images is the calibration of the Hounsfield units (HU) to density. The aim of this thesis, developed at the Policlinic of Modena, is to assert a methodology for the characterization of the HU-to-density calibration curve, and to evaluate the impact of the calibration phantom inserts composition and ph
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Nedelman, Cassandra B., and L. Lee Glenn. "Effect of Tissue Plasminogen Activator Dose and Interval on Stroke Severity." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7480.

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Excerpt: The recent study by Sahlas et al1 in the Journal of Stroke and Cerebrovascular Diseases concluded that “the estimation of a patient's weight in the acute setting can lead to overcalculation of the tissue plasminogen activator dose, which is associated with poorer functional outcomes.” However, this conclusion is not well supported by their study1 because the most severe ischemic stroke cases were the ones that were most likely not weighed, and this severity could have led to the increased mortality that was found2 and the majority of unweighed patients were actually given an underdose
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Adamus-Górka, Magdalena. "Improved dose response modeling for normal tissue damage and therapy optimization." Doctoral thesis, Stockholm University, Medical Radiation Physics (together with KI), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7433.

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<p>The present thesis is focused on the development and application of dose response models for radiation therapy. Radiobiological models of tissue response to radiation are an integral part of the radiotherapeutic process and a powerful tool to optimize tumor control and minimize damage to healthy tissues for use in clinical trials. Ideally, the models could work as a historical control arm of a clinical trial eliminating the need to randomize patents to suboptimal therapies. In the thesis overview part, some of the basic properties of the dose response relation are reviewed and the most comm
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Ström, Jakob. "The dose-dependent effects of estrogens on ischemic stroke." Doctoral thesis, Linköpings universitet, Klinisk kemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-77193.

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Estrogens are a group of female sex hormones that in addition to central roles in reproductive functions also have profound impact on for example brain development, blood vessels, bone tissue, metabolism and the immune system. The dominant endogenous production sites for estrogens in females are the ovaries and adipose tissue, while exogenous sources include combined contraceptive hormone treatments and menopausal hormone therapy. A few decades ago, the observation that females in comparison to men seemed to be protected against cerebral ischemia, and that this benefit was partially lost durin
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