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Journal articles on the topic 'Domain Studies'

Author: Grafiati

Published: 8 September 2023

Last updated: 31 July 2025

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1

Dix, Samuel R., Ruyue Sun, Matthew J. Harris, et al. "TssA from Aeromonas hydrophila: expression, purification and crystallographic studies." Acta Crystallographica Section F Structural Biology Communications 74, no. 9 (2018): 578–82. http://dx.doi.org/10.1107/s2053230x18010439.

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TssA is a core subunit of the type VI secretion system, which is a major player in interspecies competition in Gram-negative bacteria. Previous studies on enteroaggregative Escherichia coli TssA suggested that it is comprised of three putative domains: a conserved N-terminal domain, a middle domain and a ring-forming C-terminal domain. X-ray studies of the latter two domains have identified their respective structures. Here, the results of the expression and purification of full-length and domain constructs of TssA from Aeromonas hydrophila are reported, resulting in diffraction-quality crysta

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Min, Jinrong. "Structure-based chemical probe development of the PWWP domain containing proteins." Structural Dynamics 12, no. 2_Supplement (2025): A344. https://doi.org/10.1063/4.0000650.

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The PWWP domain was first identified as a structural motif of 100-130 amino acids in the WHSC1 protein and predicted to be a protein-protein interaction domain. It belongs to the Tudor domain 'Royal Family', which consists of Tudor, chromodomain, MBT and PWWP domains. PWWP domain-containing proteins are often involved in chromatin-associated biological processes, such as transcriptional regulation and DNA repair, and recent studies have shown that the PWWP domain specifies chromatin localization. Mutations in the PWWP domain, a 100-150 amino acid motif, have been linked to various human diseas

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Berbesi, Anderson, and Natália Tognoli. "Critical Archival Studies: Exploring an Emerging Domain." KNOWLEDGE ORGANIZATION 51, no. 8 (2024): 600–609. https://doi.org/10.5771/0943-7444-2024-8-600.

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This article explores critical archival studies as an emerging trend in the archival field, analyzing its relationship with domain analysis (DA), a methodological-theoretical approach within knowledge organization (KO). The objectives are: 1) to position critical archival studies as a research area of interest for KO, and 2) to evaluate their potential as an emergent domain according to DA. The methodology employed was a literature review, prioritizing seminal works on DA, critical archival studies, and their theoretical intersection. The findings highlight that critical archival studies, conc

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Sherman, Michael B., Alexis N. Williams, Hong Q. Smith, B. Montgomery Pettitt, Christiane E. Wobus, and Thomas J. Smith. "Structural Studies on the Shapeshifting Murine Norovirus." Viruses 13, no. 11 (2021): 2162. http://dx.doi.org/10.3390/v13112162.

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Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. The calicivirus capsid is composed of 180 copies of VP1 with a molecular weight of ~58 kDa. This coat protein is divided into the N-terminus (N), the shell (S) and C-terminal protruding (P) domains. The S domain forms a shell around the viral RNA genome, while the P domains dimerize to form protrusions on the capsid surface. The P domain is subdivided into P1 and P2 subdomains, with the latter containing the binding sites for cellular receptors and neutralizing antibodies. Reviewed here are studies on mur

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Du, Jiangfeng, Kanin Wichapong, Tilman M. Hackeng, and Gerry A. F. Nicolaes. "Molecular simulation studies of human coagulation factor VIII C domain-mediated membrane binding." Thrombosis and Haemostasis 113, no. 02 (2015): 373–84. http://dx.doi.org/10.1160/th14-02-0180.

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SummaryThe C-terminal C domains of activated coagulation factor VIII (FVIIIa) are essential to membrane binding of this crucial coagulation cofactor protein. To provide an overall membrane binding mechanism for FVIII, we performed simulations of membrane binding through coarsegrained molecular dynamics simulations of the C1 and C2 domain, and the combined C-domains (C1+C2). We found that the C1 and C2 domain have different membrane binding properties. The C1 domain uses hydrophobic spikes 3 and 4, of its total of four spikes, as major loops to bind the membrane, whereas all four of its hydroph

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Patel, S. D., and C. I. Ragan. "Structural studies on mitochondrial NADH dehydrogenase using chemical cross-linking." Biochemical Journal 256, no. 2 (1988): 521–28. http://dx.doi.org/10.1042/bj2560521.

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The structure of bovine heart mitochondrial NADH dehydrogenase was investigated by cross-linking constituent subunits with disuccinimidyl tartrate, (ethylene glycol)yl bis(succinimidyl succinate) and dimethyl suberimidate. Cross-linked products were identified by Western blotting with monospecific antisera to nine subunits of the enzyme. Cross-links between subunits within the flavoprotein, iron-protein and hydrophobic domains of the enzyme were identified. Cross-linking between the 75 kDa iron-protein-domain subunit and the 51 kDa flavoprotein-domain subunit was modulated by the substrate NAD

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7

Barité, Mario, and Mirtha Rauch. "Terminological studies as domain analysis." Brazilian Journal of Information Science: research trends 16 (April 5, 2022): e02140. http://dx.doi.org/10.36311/1981-1640.2022.v16.e02140.

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This paper aims to thoroughly analyze terminological studies as a particular modality of domain analysis (DA). To this end, we establish the following methodological sequence: i) a broad description of the field of terminology, with emphasis on a general characterization of the theoretical currents and the two traditional types of research: systematic research and punctual research; ii) review of the background information on the theoretical and methodological intersection between terminology and knowledge organization (KO); iii) the problematization of terminological studies seen as DA, based

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8

Hutchings, J. B. "Time-Domain Studies with Astrosat." Proceedings of the International Astronomical Union 14, S339 (2017): 117–20. http://dx.doi.org/10.1017/s1743921318002351.

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AbstractAstrosat is a multi-instrument orbiting observatory that was launched in 2015 by the Indian Space Research Organization (ISRO). The same field of view is observed simultaneously at wavelengths ranging from gamma ray to the optical blue. This talk described the observatory’s performance, with emphasis on time-domain studies, and gave examples of results.

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Ponomarev, D. M., A. V. Goryachev, V. N. Zhavoronkov, and S. V. Goryunova. "Experimental time-domain antenna studies." Radiophysics and Quantum Electronics 30, no. 8 (1987): 763–67. http://dx.doi.org/10.1007/bf01083488.

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10

Lee, C. H. "Time-domain studies of M31." Astronomical Review 12, no. 1-4 (2016): 1–23. http://dx.doi.org/10.1080/21672857.2016.1270028.

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11

Peek, James, and Dinesh Christendat. "Structural studies on dehydroshikimate dehydratase." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C475. http://dx.doi.org/10.1107/s2053273314095242.

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The soil bacterium, Pseudomonas putida, is capable of using the alicyclic compound quinate as a sole carbon source. During this process, quinate is converted to 3-dehydroshikimate, which subsequently undergoes a dehydration to form protocatechuate. The latter transformation is performed by the enzyme dehydroshikimate dehydratase (DSD). We have recombinantly produced DSD from P. putida and are currently performing x-ray crystallographic studies on the enzyme to gain structural insight into its catalytic mechanism and mode of substrate recognition. Initial crystals of DSD diffracted to 2.7 Ä res

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12

Feke, Ann, Morgan Vanderwall, Wei Liu, and Joshua M. Gendron. "Functional domain studies uncover novel roles for the ZTL Kelch repeat domain in clock function." PLOS ONE 16, no. 3 (2021): e0235938. http://dx.doi.org/10.1371/journal.pone.0235938.

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The small LOV/F-box/Kelch family of E3 ubiquitin ligases plays an essential role in the regulation of plant circadian clocks and flowering time by sensing dusk. The family consists of three members, ZEITLUPE (ZTL), LOV KELCH PROTEIN 2 (LKP2), and FLAVIN-BINDING KELCH REPEAT F-BOX PROTEIN 1 (FKF1), which share a unique protein domain architecture allowing them to act as photoreceptors that transduce light signals via altering stability of target proteins. Despite intensive study of this protein family we still lack important knowledge about the biochemical and functional roles of the protein do

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13

Liljas, Anders, Arnthor Ævarsson, Salam Al-Karadaghi, Maria Garber, Julia Zheltonosova, and Evgeni Brazhnikov. "Crystallographic studies of elongation factor G." Biochemistry and Cell Biology 73, no. 11-12 (1995): 1209–16. http://dx.doi.org/10.1139/o95-130.

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The elongation factors G (EF-G) and Tu (EF-Tu) go through a number of conformation states in their functional cycles. Since they both are GTPases, have similar G domains and domains II, and have similar interactions with the nucleotides, then GTP hydrolysis must occur in similar ways. The crystal structures of two conformational states are known for EF-G and three are known for EF-Tu. The conformations of EF-G∙GDP and EF-Tu∙GTP are closely related. EF-Tu goes through a large conformational change upon GTP cleavage. This conformational change is to a large extent due to an altered interaction b

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Amin, Nader T., A. Katrine Wallis, Stephen A. Wells, et al. "High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility." Biochemical Journal 450, no. 2 (2013): 321–32. http://dx.doi.org/10.1042/bj20121635.

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ERp27 (endoplasmic reticulum protein 27.7 kDa) is a homologue of PDI (protein disulfide-isomerase) localized to the endoplasmic reticulum. ERp27 is predicted to consist of two thioredoxin-fold domains homologous with the non-catalytic b and b′ domains of PDI. The structure in solution of the N-terminal b-like domain of ERp27 was solved using high-resolution NMR data. The structure confirms that it has the thioredoxin fold and that ERp27 is a member of the PDI family. 15N-NMR relaxation data were obtained and ModelFree analysis highlighted limited exchange contributions and slow internal motion

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15

Inoue, T., and K. Goto. "Studies of Single-Domain Particles of Sm2Co17 by Domain Observation." IEEE Translation Journal on Magnetics in Japan 1, no. 8 (1985): 992–93. http://dx.doi.org/10.1109/tjmj.1985.4549044.

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16

Kolade, O. O., P. Bellini, M. Wexler, A. W. B. Johnston, J. G. Grossmann, and A. M. Hemmings. "Structural studies of the Fur protein from Rhizobium leguminosarum." Biochemical Society Transactions 30, no. 4 (2002): 771–74. http://dx.doi.org/10.1042/bst0300771.

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The X-ray crystal structure of the apo-form of the Fur protein from Rhizobium leguminosarum has been solved at 2.7 å resolution. Small-angle X-ray scattering was used to give information on the solution conformation of the protein. The Fur homodimer folds into two domains. The N-terminal domain is formed from the packing of two helix-turn-helix motifs while the C-terminal domain appears primarily to stabilize the dimeric state of the protein.

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Darch, Peter T., and Christine L. Borgman. "Ship space to database: emerging infrastructures for studies of the deep subseafloor biosphere." PeerJ Computer Science 2 (November 14, 2016): e97. http://dx.doi.org/10.7717/peerj-cs.97.

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BackgroundAn increasing array of scientific fields face a “data deluge.” However, in many fields data are scarce, with implications for their epistemic status and ability to command funding. Consequently, they often attempt to develop infrastructure for data production, management, curation, and circulation. A component of a knowledge infrastructure may serve one or more scientific domains. Further, a single domain may rely upon multiple infrastructures simultaneously. Studying how domains negotiate building and accessing scarce infrastructural resources that they share with other domains will

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18

Pigott, R., L. A. Needham, R. M. Edwards, C. Walker, and C. Power. "Structural and functional studies of the endothelial activation antigen endothelial leucocyte adhesion molecule-1 using a panel of monoclonal antibodies." Journal of Immunology 147, no. 1 (1991): 130–35. http://dx.doi.org/10.4049/jimmunol.147.1.130.

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Abstract We have produced a panel of mAb to the endothelial activation Ag endothelial leucocyte adhesion molecule-1 (ELAM-1), using both a conventional immunization protocol and one involving immunosuppression. By constructing ELAM-1 mutants we have demonstrated that seven of these antibodies recognize epitopes within the lectin domain of ELAM-1 and that one binds within the complement regulatory protein domains. These studies also suggest that the EGF-like domain is important in maintaining the conformation of the neighbouring lectin domain. In functional studies, U937 cells bound to Cos cell

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Chandran, Anu V., J. Rajan Prabu, G. P. Manjunath, K. Neelakanteshwar Patil, K. Muniyappa, and M. Vijayan. "Crystallization and preliminary X-ray studies of the C-terminal domain ofMycobacterium tuberculosisLexA." Acta Crystallographica Section F Structural Biology and Crystallization Communications 66, no. 9 (2010): 1093–95. http://dx.doi.org/10.1107/s174430911003068x.

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The C-terminal domain ofMycobacterium tuberculosisLexA has been crystallized in two different forms. The form 1 and form 2 crystals belonged to space groupsP3121 andP31, respectively. Form 1 contains one domain in the asymmetric unit, while form 2 contains six crystallographically independent domains. The structures have been solved by molecular replacement.

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Cavet, M., CM Tse, S. Akhter, C. Yun, and M. Donowitz. "Structure-function studies of membrane domain-cytoplasmic domain and membrane domain-membrane doman chimeras of Na+/H+ exchanger isoforms NHE1 and NHE3." Gastroenterology 114 (April 1998): A357. http://dx.doi.org/10.1016/s0016-5085(98)81447-9.

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21

Snyder, Greg, Jiansheng Jiang, Kang Chen, et al. "Structural studies of Toll like receptor signaling adaptors. (136.45)." Journal of Immunology 184, no. 1_Supplement (2010): 136.45. http://dx.doi.org/10.4049/jimmunol.184.supp.136.45.

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Abstract Signaling downstream of the Toll like receptors (TLRs) involves Toll-IL-1R homology (TIR) domains as well as recruitment of critical signaling adaptors MyD88 and TIRAP/Mal. Studies in human patients, dominant negative mutants and knockout mice have shown that mutations in Arg196, the BB loop, DD loop, “Poc” site Ile179 are critical for MyD88 TIR domain signaling and appropriate responses to pathogen stimuli. We previously reported the structure of MyD88 TIR domain that showed a unique conformation for its BB loop, as well as a crystallographic lattice that reveals interactions between

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Gill, David J., Hsiangling Teo, Ji Sun, et al. "Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies." Biochemical Society Symposia 74 (January 12, 2007): 47–57. http://dx.doi.org/10.1042/bss2007c05.

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Three large protein complexes known as ESCRT I, ESCRT II and ESCRT III drive the progression of ubiquitinated membrane cargo from early endosomes to lysosomes. Several steps in this process critically depend on PtdIns3P, the product of the class III phosphoinositide 3-kinase. Our work has provided insights into the architecture, membrane recruitment and functional interactions of the ESCRT machinery. The fan-shaped ESCRT I core and the trilobal ESCRT II core are essential to forming stable, rigid scaffolds that support additional, flexibly-linked domains, which serve as gripping tools for reco

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Jacobsson, Mattias, and Anders Söderholm. "Project Studies Beyond the Straitjacket: An Escape Artist’s Manual." Project Management Journal 51, no. 4 (2020): 411–19. http://dx.doi.org/10.1177/8756972820929916.

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This article provides insights into ways in which project studies can be extended to make further impact on and contributions to other research domains, including more general management and organization studies. Inspired by literature on the phenomenology of science, publication practices, logics of research communities, and theory building, we analyze some examples of project studies that reach beyond the project domain. Based on this analysis, we present an “escape artist’s manual” consisting of strategies and practices for how researchers could think about and design project studies to ena

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24

Zhou, Jia, Bin He, Yaoyu He, et al. "Measurement properties of family resilience assessment questionnaires: a systematic review." Family Practice 37, no. 5 (2020): 581–91. http://dx.doi.org/10.1093/fampra/cmaa027.

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Abstract Background There have been numerous measurement questionnaires to estimate the level of family resilience. However, we lack published evidence regarding the most appropriate family resilience questionnaire in different adversity domains. Objective This study critically assesses and contrasts the measurement properties of questionnaires measuring family resilience in two domains: health care domain and social domain. Methods Ten electronic databases were searched for studies concerning the establishment, adaptation or evaluation of the measurement properties of a family resilience asse

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Stockman, Caroline, and Fred Truyen. "Cultural Studies as Performative Research in a Digital Age." European Review 22, no. 2 (2014): 309–20. http://dx.doi.org/10.1017/s1062798714000131.

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This paper aims to explore the nature of digital culture research, and the fitting methodology. Although it is still felt to be a novelty, it is not so different from the more general domain of Cultural Studies. The aim of research for both domains is meaning, or the challenge to understand the dynamics of the encoding and decoding process. Both domains endorse a wide variety of subjects, although typically the concrete methodology of Cultural Studies still remains restricted to qualitative approaches. The question of quantitative data and their analysis is highlighted in digital culture, and

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Li, J., G. I. Lee, S. R. Van Doren, and J. C. Walker. "The FHA domain mediates phosphoprotein interactions." Journal of Cell Science 113, no. 23 (2000): 4143–49. http://dx.doi.org/10.1242/jcs.113.23.4143.

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The forkhead-associated (FHA) domain is a phosphopeptide-binding domain first identified in a group of forkhead transcription factors but is present in a wide variety of proteins from both prokaryotes and eukaryotes. In yeast and human, many proteins containing an FHA domain are found in the nucleus and involved in DNA repair, cell cycle arrest, or pre-mRNA processing. In plants, the FHA domain is part of a protein that is localized to the plasma membrane and participates in the regulation of receptor-like protein kinase signaling pathways. Recent studies show that a functional FHA domain cons

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Yamamoto, R., Y. Ueda, H. Yamamoto, A. Kikuchi, N. Shibata, and Y. Higuchi. "Crystallographic studies of Axin-DIX domain." Seibutsu Butsuri 43, supplement (2003): S37. http://dx.doi.org/10.2142/biophys.43.s37_4.

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Cheville, R. A., and D. Grischkowsky. "Time domain terahertz impulse ranging studies." Applied Physics Letters 67, no. 14 (1995): 1960–62. http://dx.doi.org/10.1063/1.114579.

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Papathanassiou, A. N., J. Grammatikakis, and N. G. Bogris. "Frequency-domain dielectric studies in LiF:Ca2+." Physical Review B 49, no. 20 (1994): 14160–64. http://dx.doi.org/10.1103/physrevb.49.14160.

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Nagaraja, H. S., K. K. Nagaraja, F. Rossignol, F. Dumas-Bouchiat, C. Champeaux, and A. Catherinot. "Magnetic Domain Studies of Cobalt Nanostructures." Journal of Superconductivity and Novel Magnetism 25, no. 6 (2012): 1901–6. http://dx.doi.org/10.1007/s10948-012-1508-2.

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YUZAWA, MASAMICHI. "From Design Studies for Domain-Specific Conceptual Changes Back to Studies Dealing with Domain-General Skills :." Annual Report of Educational Psychology in Japan 53 (2014): 166–79. http://dx.doi.org/10.5926/arepj.53.166.

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Crawford, C., N. R. Brown, and A. C. Willis. "Studies of the active site of m-calpain and the interaction with calpastatin." Biochemical Journal 296, no. 1 (1993): 135–42. http://dx.doi.org/10.1042/bj2960135.

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Calpain autolyses in the presence of Ca2+. In the case of m-calpain (80 + 30 kDa) the first product is an 80 + 18 kDa species which has an intact large subunit and the C-terminal Ca(2+)-binding domain of the small subunit. It was possible to bind E64 into the active site of calpain in the presence of Ca2+ before cleavage of either calpain subunit. This suggests that the active site is functional before any autolysis has occurred and that calpain is not a proenzyme. Prolonged autolysis generates several fragments including a 42 kDa active-site domain fragment that showed no proteolytic activity

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Aluru, Chaitanya, and Mona Singh. "Improved inference of tandem domain duplications." Bioinformatics 37, Supplement_1 (2021): i133—i141. http://dx.doi.org/10.1093/bioinformatics/btab329.

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Abstract Motivation Protein domain duplications are a major contributor to the functional diversification of protein families. These duplications can occur one at a time through single domain duplications, or as tandem duplications where several consecutive domains are duplicated together as part of a single evolutionary event. Existing methods for inferring domain-level evolutionary events are based on reconciling domain trees with gene trees. While some formulations consider multiple domain duplications, they do not explicitly model tandem duplications; this leads to inaccurate inference of

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Cheang, Qing Wei, Lingyi Xin, Rachel Yuen Fong Chea, and Zhao-Xun Liang. "Emerging paradigms for PilZ domain-mediated C-di-GMP signaling." Biochemical Society Transactions 47, no. 1 (2019): 381–88. http://dx.doi.org/10.1042/bst20180543.

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Abstract PilZ domain-containing proteins constitute a large family of bacterial signaling proteins. As a widely distributed protein domain for the binding of the second messenger c-di-GMP, the canonical PilZ domain contains a set of motifs that define the binding site for c-di-GMP and an allosteric switch for propagating local conformational changes. Here, we summarize some new insights gathered from recent studies on the commonly occurring single-domain PilZ proteins, YcgR-like proteins and PilZ domain-containing cellulose synthases. The studies collectively illuminate how PilZ domains functi

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Wong, Kathy, Yinglu Zhang, Guennadi Kozlov, and Kalle Gehring. "Structural studies of Legionella effectors." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C583. http://dx.doi.org/10.1107/s2053273314094169.

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Legionella pneumophila is a gram-negative bacterium that causes Legionnaires' disease. It uses a Dot/Icm type IV secretion system to inject effector proteins into the host cell to manipulate host processes. Currently, about 300 Icm/Dot dependent effectors of L.pneumophila have been identified. Lpg1496 is an effector protein, which contains a conserved domain from the SidE family. To date, the middle domain and the conserved SidE domain have been crystallized and the structure solved at a resolution of 1.15Å and 2.3Å, respectively. A structural homology search using the middle domain suggested

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Bherer, Louis. "MULTIDOMAIN INTERVENTION TO IMPROVE COGNITION IN OLDER ADULTS: NEW RESULTS AND FUTURE CHALLENGES." Innovation in Aging 8, Supplement_1 (2024): 668. https://doi.org/10.1093/geroni/igae098.2185.

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Abstract Decades of research have supported the notion that physical exercise and cognitive training can both help enhance cognitive performances in older adults. More recent studies have investigated whether these two domains of intervention could have synergistic effects, however results are equivocal. Moreover, there is an important heterogeneity among studies with regards to intervention modality within domain (e.g., memory or attention training as cognitive intervention; aerobic, resistance or combined physical exercise) and studied population (MCI vs. healthy aging). This symposium will

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Wells, C., K. E. Warriner, and C. R. Bagshaw. "Fluorescence studies on the nucleotide- and Ca2+-binding domains of molluscan myosin." Biochemical Journal 231, no. 1 (1985): 31–38. http://dx.doi.org/10.1042/bj2310031.

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The effects of nucleotides and Ca2+ on the intrinsic tryptophan fluorescence of molluscan myosin and its proteolytic fragments were studied. By using these proteins from the scallop, Pecten maximus, the existence of two distinct tryptophan-containing domains was established, which respond independently to ATP and Ca2+-specific binding. The latter is located in the ‘neck’ region of the myosin, which constitutes the regulatory domain. Subfragment 1, lacking the regulatory domain, responded only to ATP binding. On the other hand a tryptic fragment comprising the regulatory domain responded only t

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Lee, Sujin, and Mihyoung Lee. "Analysis of Nursing Intervention Studies Published by the Journal of Korean Academy of Psychiatric and Mental Health Nursing Using the NANDA, NIC, and NOC*." Journal of Korean Academy of psychiatric and Mental Health Nursing 16, no. 4 (2007): 377–88. http://dx.doi.org/10.12934/jkpmhn.2007.16.4.377.

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Purpose: This study sought to investigate the research trends of nursing intervention by analyzing of Nursing Studies using the NANDA, NIC, and NOC. Methods: The subjects were 72 intervention studies published by the Journal of Korean Academy of Psychiatric and Mental Health Nursing from 1992 to 2006. The data were analyzed by NANDA, NIC, and NOC. Results: Regarding the distribution of NANDA, NIC, and NOC, at the level of the NANDA domain, “role relatkmship” domain was largest, with a distribution of 29.0%, followed by “coping/stress tolerance” at 21.6% distribution; at the level of the NIC do

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Xie, Renchunzi, Hongxin Wei, Lei Feng, and Bo An. "GearNet: Stepwise Dual Learning for Weakly Supervised Domain Adaptation." Proceedings of the AAAI Conference on Artificial Intelligence 36, no. 8 (2022): 8717–25. http://dx.doi.org/10.1609/aaai.v36i8.20851.

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This paper studies a weakly supervised domain adaptation (WSDA) problem, where we only have access to the source domain with noisy labels, from which we need to transfer useful information to the unlabeled target domain. Although there have been a few studies on this problem, most of them only exploit unidirectional relationships from the source domain to the target domain. In this paper, we propose a universal paradigm called GearNet to exploit bilateral relationships between the two domains. Specifically, we take the two domains as different inputs to train two models alternately, and a symm

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Vishkin, Allon, Yochanan E. Bigman, and Jeremy Ginges. "Belief in Creation in the Image of God Violates the Individualizing-Binding Dichotomy of Moral Foundations." Journal of Cross-Cultural Psychology 56, no. 4 (2025): 380–401. https://doi.org/10.1177/00220221241279222.

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Moral foundations theory proposes that there are two types of moral domains: the individualizing domain, which relates to individual welfare (comprising harm and fairness foundations), and the binding domain, which relates to communal and spiritual welfare (comprising loyalty, authority, and purity foundations). In this investigation, we demonstrate that this distinction is not universal. Specifically, across five studies (total N = 1,211) conducted among Jews in Israel and Christians in the United States, we show that the core religious belief that people are created in the image of God is as

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Demczyk, B. G. "Domains and domain nucleation in magnetron-sputtered CoCr thin films." Proceedings, annual meeting, Electron Microscopy Society of America 51 (August 1, 1993): 1046–47. http://dx.doi.org/10.1017/s0424820100151064.

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CoCr thin films have been of interest for a number of years due to their strong perpendicular anisotropy, favoring magnetization normal to the film plane. The microstructure and magnetic properties of CoCr films prepared by both rf and magnetron sputtering have been examined in detail. By comparison, however, relatively few systematic studies of the magnetic domain structure and its relation to the observed film microstructure have been reported. In addition, questions still remain as to the operative magnetization reversal mechanism in different film thickness regimes. In this work, the magne

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Peterson, A. J., M. Kyba, D. Bornemann, K. Morgan, H. W. Brock, and J. Simon. "A domain shared by the Polycomb group proteins Scm and ph mediates heterotypic and homotypic interactions." Molecular and Cellular Biology 17, no. 11 (1997): 6683–92. http://dx.doi.org/10.1128/mcb.17.11.6683.

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The Sex comb on midleg (Scm) and polyhomeotic (ph) proteins are members of the Polycomb group (PcG) of transcriptional repressors. PcG proteins maintain differential patterns of homeotic gene expression during development in Drosophila flies. The Scm and ph proteins share a homology domain with 38% identity over a length of 65 amino acids, termed the SPM domain, that is located at their respective C termini. Using the yeast two-hybrid system and in vitro protein-binding assays, we show that the SPM domain mediates direct interaction between Scm and ph. Binding studies with isolated SPM domains

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Constantine, K. L., S. A. Brew, K. C. Ingham, and M. Llinás. "1H-n.m.r. studies of the fibronectin 13kDa collagen-binding fragment. Evidence for autonomous conserved type I and type II domain folds." Biochemical Journal 283, no. 1 (1992): 247–54. http://dx.doi.org/10.1042/bj2830247.

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A 1H-n.m.r. study of a 117-residue (13 kDa) gelatin-binding fragment of human fibronectin, which contains the sixth (from the N-terminus) type I domain and the first type II domain, was undertaken. The resolution of the 1H-n.m.r. spectrum indicates that the domains are independent and mobile relative to each other. Analysis of two-dimensional 1H-n.m.r. experiments recorded at 500 MHz afforded spin-system identifications for all aromatic and a number of aliphatic residues. Utilizing the fact that phenylalanine residues occur only in the type II portion of this fragment, many spin systems were l

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Mathivanan, Subashini, Sreeja Chellappan, R. Thippeswamy, M. Nagesh, H. S. Savithri, and M. R. N. Murthy. "Structural studies on oxalate decarboxylase from Photorhabdus luminescens." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C1821. http://dx.doi.org/10.1107/s2053273314081790.

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As a part of exploration of novel bacterial genes coding for insecticidal proteins, we have initiated structural and functional studies on oxalate decarboxylase from Photorhabdus luminescens, a symbiotic bacteria inhabiting guts of nematodes that parasitize insects. Oxalate decarboxylases (OXDC) are enzymes that catalyze the conversion of oxalate to formate and carbondioxide (CO2) in the presence of manganese and dioxygen. Structures of OXDC in complex with ethylene glycol (EDO), EDO/formate (FMT) and FMT/CO2 were determined at resolutions of 1.97Å, 2.36Å and 2.5Å, respectively. The asymmetric

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Guo, Chunfeng, Bin Wei, and Kun Yu. "Deep Transfer Learning for Biology Cross-Domain Image Classification." Journal of Control Science and Engineering 2021 (December 15, 2021): 1–19. http://dx.doi.org/10.1155/2021/2518837.

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Automatic biology image classification is essential for biodiversity conservation and ecological study. Recently, due to the record-shattering performance, deep convolutional neural networks (DCNNs) have been used more often in biology image classification. However, training DCNNs requires a large amount of labeled data, which may be difficult to collect for some organisms. This study was carried out to exploit cross-domain transfer learning for DCNNs with limited data. According to the literature, previous studies mainly focus on transferring from ImageNet to a specific domain or transferring

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Bykerk, Vivian P., Elisabeth Lie, Susan J. Bartlett, et al. "Establishing a Core Domain Set to Measure Rheumatoid Arthritis Flares: Report of the OMERACT 11 RA Flare Workshop." Journal of Rheumatology 41, no. 4 (2014): 799–809. http://dx.doi.org/10.3899/jrheum.131252.

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Objective.The OMERACT Rheumatoid Arthritis (RA) Flare Group (FG) is developing a data-driven, patient-inclusive, consensus-based RA flare definition for use in clinical trials, longterm observational studies, and clinical practice. At OMERACT 11, we sought endorsement of a proposed core domain set to measure RA flare.Methods.Patient and healthcare professional (HCP) qualitative studies, focus groups, and literature review, followed by patient and HCP Delphi exercises including combined Delphi consensus at Outcome Measures in Rheumatology 10 (OMERACT 10), identified potential domains to measure

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Van de Wiele, Ben, Arne Vansteenkiste, Bartel Van Waeyenberge, Luc Dupré, and Daniel De Zutter. "A 2.5D micromagnetic modeling approach for magnetic domain and domain wall studies." International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 27, no. 3 (2013): 450–60. http://dx.doi.org/10.1002/jnm.1953.

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Deryusheva, Evgenia I., Andrey V. Machulin, Maxim A. Matyunin, and Oxana V. Galzitskaya. "Investigation of the Relationship between the S1 Domain and Its Molecular Functions Derived from Studies of the Tertiary Structure." Molecules 24, no. 20 (2019): 3681. http://dx.doi.org/10.3390/molecules24203681.

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S1 domain, a structural variant of one of the “oldest” OB-folds (oligonucleotide/oligosaccharide-binding fold), is widespread in various proteins in three domains of life: Bacteria, Eukaryotes, and Archaea. In this study, it was shown that S1 domains of bacterial, eukaryotic, and archaeal proteins have a low percentage of identity, which indicates the uniqueness of the scaffold and is associated with protein functions. Assessment of the predisposition of tertiary flexibility of S1 domains using computational and statistical tools showed similar structural features and revealed functional flexi

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Schorb, J. "MASTERS OF THEIR DOMAIN." GLQ: A Journal of Lesbian and Gay Studies 15, no. 3 (2009): 516–18. http://dx.doi.org/10.1215/10642684-2008-036.

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Gozdek, Agnieszka, Anna Stankiewicz-Drogoń, Jarosław Poznański, and Anna M. Boguszewska-Chachulska. "Circular dichroism analysis for multidomain proteins: studies of the irreversible unfolding of Hepatitis C virus helicase." Acta Biochimica Polonica 55, no. 1 (2008): 57–66. http://dx.doi.org/10.18388/abp.2008_3201.

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The non-structural protein 3 (NS3) of Hepatitis C virus (HCV) is a bifunctional enzyme with RNA-dependent NTPase/RNA helicase and serine protease activities, and thus represents a promising target for anti-HCV therapy. These functions are performed by two distinct moieties; the N-terminal protease domain and the C-terminal helicase domain that further folds into three structural subdomains. To obtain lower molecular mass proteins suitable for nuclear magnetic resonance studies of helicase-inhibitor complexes, helicase domains 1, 2, and 1+2 devoid of a hydrophobic beta-loop were overexpressed a

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