Relevant bibliographies by topics / Dopaminergic neurons

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Dopaminergic neurons'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Dopaminergic neurons"

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Niu, Shiba, Weibo Shi, Yingmin Li, et al. "Endoplasmic Reticulum Stress Is Associated with the Mesencephalic Dopaminergic Neuron Injury in Stressed Rats." Analytical Cellular Pathology 2021 (September 8, 2021): 1–9. http://dx.doi.org/10.1155/2021/7852710.

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An increasing number of people are in a state of stress due to social and psychological pressures, which may result in mental disorders. Previous studies indicated that mesencephalic dopaminergic neurons are associated with not only reward-related behaviors but also with stress-induced mental disorders. To explore the effect of stress on dopaminergic neuron and potential mechanism, we established stressed rat models of different time durations and observed pathological changes in dopaminergic neurons of the ventral tegmental area (VTA) through HE and thionine staining. Immunohistochemistry cou
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Jovanovic, Predrag, Yidan Wang, Jean-Philippe Vit, et al. "Sustained chemogenetic activation of locus coeruleus norepinephrine neurons promotes dopaminergic neuron survival in synucleinopathy." PLOS ONE 17, no. 3 (2022): e0263074. http://dx.doi.org/10.1371/journal.pone.0263074.

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Dopaminergic neuron degeneration in the midbrain plays a pivotal role in motor symptoms associated with Parkinson’s disease. However, non-motor symptoms of Parkinson’s disease and post-mortem histopathology confirm dysfunction in other brain areas, including the locus coeruleus and its associated neurotransmitter norepinephrine. Here, we investigate the role of central norepinephrine-producing neurons in Parkinson’s disease by chronically stimulating catecholaminergic neurons in the locus coeruleus using chemogenetic manipulation. We show that norepinephrine neurons send complex axonal project
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Dodson, Paul D., Jakob K. Dreyer, Katie A. Jennings, et al. "Representation of spontaneous movement by dopaminergic neurons is cell-type selective and disrupted in parkinsonism." Proceedings of the National Academy of Sciences 113, no. 15 (2016): E2180—E2188. http://dx.doi.org/10.1073/pnas.1515941113.

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Midbrain dopaminergic neurons are essential for appropriate voluntary movement, as epitomized by the cardinal motor impairments arising in Parkinson’s disease. Understanding the basis of such motor control requires understanding how the firing of different types of dopaminergic neuron relates to movement and how this activity is deciphered in target structures such as the striatum. By recording and labeling individual neurons in behaving mice, we show that the representation of brief spontaneous movements in the firing of identified midbrain dopaminergic neurons is cell-type selective. Most do
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Basso, Valentina, Máté D. Döbrössy, Lachlan H. Thompson, Deniz Kirik, Heidi R. Fuller, and Monte A. Gates. "State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons." Biology 13, no. 9 (2024): 690. http://dx.doi.org/10.3390/biology13090690.

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Dopaminergic neurons in the ventral tegmental area (VTA) and the substantia nigra pars compacta (SNpc) comprise around 75% of all dopaminergic neurons in the human brain. While both groups of dopaminergic neurons are in close proximity in the midbrain and partially overlap, development, function, and impairments in these two classes of neurons are highly diverse. The molecular and cellular mechanisms underlying these differences are not yet fully understood, but research over the past decade has highlighted the need to differentiate between these two classes of dopaminergic neurons during thei
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Chinta, Shankar J., and Julie K. Andersen. "Dopaminergic neurons." International Journal of Biochemistry & Cell Biology 37, no. 5 (2005): 942–46. http://dx.doi.org/10.1016/j.biocel.2004.09.009.

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Na, Junewoo, Byong Seo Park, Doohyeong Jang, et al. "Distinct Firing Activities of the Hypothalamic Arcuate Nucleus Neurons to Appetite Hormones." International Journal of Molecular Sciences 23, no. 5 (2022): 2609. http://dx.doi.org/10.3390/ijms23052609.

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The hypothalamic arcuate nucleus (Arc) is a central unit that controls the appetite through the integration of metabolic, hormonal, and neuronal afferent inputs. Agouti-related protein (AgRP), proopiomelanocortin (POMC), and dopaminergic neurons in the Arc differentially regulate feeding behaviors in response to hunger, satiety, and appetite, respectively. At the time of writing, the anatomical and electrophysiological characterization of these three neurons has not yet been intensively explored. Here, we interrogated the overall characterization of AgRP, POMC, and dopaminergic neurons using g
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Orb, Sabine, Johannes Wieacker, Cesar Labarca, Carlos Fonck, Henry A. Lester та Johannes Schwarz. "Knockin mice with Leu9′Ser α4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally". Physiological Genomics 18, № 3 (2004): 299–307. http://dx.doi.org/10.1152/physiolgenomics.00012.2004.

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This study analyzes the electrophysiological cause and behavioral consequence of dopaminergic cell loss in a knockin mouse strain bearing hypersensitive nicotinic α4-receptor subunits (“L9′S mice”). Adult brains of L9′S mice show moderate loss of substantia nigra dopaminergic neurons and of striatal dopaminergic innervation. Amphetamine-stimulated locomotion is impaired, reflecting a reduction of dopamine stored in presynaptic vesicles. Recordings from dopaminergic neurons in L9′S mice show that 10 μM nicotine depolarizes cells and increases spiking rates in L9′S cells but hyperpolarizes and d
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Zhang, Nianping, Xudong Zhang, Zhaoli Yan, Ronghui Li, Song Xue, and Dahong Long. "A Modified Differentiation Protocol In Vitro to Generate Dopaminergic Neurons from Pluripotent Stem Cells." Journal of Biomaterials and Tissue Engineering 13, no. 10 (2023): 1017–25. http://dx.doi.org/10.1166/jbt.2023.3341.

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Cell transplantation is considered a promising therapeutic strategy for the treatment of Parkinson's disease. Because of their strong differentiation potential, pluripotent stem cells may become a source of dopaminergic neurons for cell transplantation. Although published protocols have revealed that pluripotent stem cells can be successfully induced into dopaminergic neurons, unwanted cell types still exist in PSC-derived cultures. Therefore, signaling parameters for dopaminergic neuron patterning in differentiation protocols need to be further identified and optimized. In this study, we expl
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Mendes-Oliveira, Julieta, Filipa L. Campos, Susana A. Ferreira, Diogo Tomé, Carla P. Fonseca, and Graça Baltazar. "Endogenous GDNF Is Unable to Halt Dopaminergic Injury Triggered by Microglial Activation." Cells 13, no. 1 (2023): 74. http://dx.doi.org/10.3390/cells13010074.

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Overactivation of microglial cells seems to play a crucial role in the degeneration of dopaminergic neurons occurring in Parkinson’s disease. We have previously demonstrated that glial cell line-derived neurotrophic factor (GDNF) present in astrocytes secretome modulates microglial responses induced by an inflammatory insult. Therefore, astrocyte-derived soluble factors may include relevant molecular players of therapeutic interest in the control of excessive neuroinflammatory responses. However, in vivo, the control of neuroinflammation is more complex as it depends on the interaction between
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Awata, Hiroko, Mai Takakura, Yoko Kimura, Ikuko Iwata, Tomoko Masuda, and Yukinori Hirano. "The neural circuit linking mushroom body parallel circuits induces memory consolidation in Drosophila." Proceedings of the National Academy of Sciences 116, no. 32 (2019): 16080–85. http://dx.doi.org/10.1073/pnas.1901292116.

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Memory consolidation is augmented by repeated learning following rest intervals, which is known as the spacing effect. Although the spacing effect has been associated with cumulative cellular responses in the neurons engaged in memory, here, we report the neural circuit-based mechanism for generating the spacing effect in the memory-related mushroom body (MB) parallel circuits in Drosophila. To investigate the neurons activated during the training, we monitored expression of phosphorylation of mitogen-activated protein kinase (MAPK), ERK [phosphorylation of extracellular signal-related kinase
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Dissertations / Theses on the topic "Dopaminergic neurons"

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DE, SANCTIS Claudia. "MicroRNAs profiling in Dopaminergic neurons." Doctoral thesis, Università degli studi del Molise, 2018. http://hdl.handle.net/11695/83499.

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Lo sviluppo dei neuroni dopaminergici mesencefalici (mDA) è un fenomeno complesso e non ancora pienamente compreso. Molti studi hanno focalizzato la loro attenzione sul ruolo svolto da diversi fattori di trascrizione specifici e ben noti. L'obiettivo della mia tesi di dottorato è focalizzato su una classe relativamente nuova di regolatori post-trascrizionali denominati microRNA (miRNAs), in grado di regolare l'espressione genica legando le sequenze parzialmente complementari nelle regioni 3' non tradotte (UTR) degli mRNAs target. Per studiare il ruolo svolto dai miRNAs durante la differenziaz
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Dommett, Eleanor Jane. "Sensory regulation of midbrain dopaminergic neurons." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425614.

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Decker, Amanda R. "TRPM7 function in zebrafish dopaminergic neurons." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/5927.

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TRPM7 (Transient Receptor Potential Melastatin-like 7) is an ion channel necessary for the proper development of many cell types. Insight into the precise role of the channel in different cells has been hampered by the lethality of knocking out the gene in model organisms such as the mouse. Here I examine a zebrafish that has a loss-of-function mutation in the gene encoding Trpm7. First, I show that trpm7 is important for the function of developing dopaminergic neurons in the zebrafish. Second, I examine the interaction between trpm7 and the related gene vmat2 in order to develop a cellular me
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Love, Rebecca Margaret. "Improving the survival of embryonic dopaminergic neurons." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343277.

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Adams, Van L. "Seasonal plasticity of A15 dopaminergic neurons in the ewe." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2096.

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Thesis (M.S.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains vii, 79 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 70-78).
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Lak, Armin. "Encoding of economic value by midbrain dopamine neurons." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648342.

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Zietlow, Rike. "Factors affecting the survival of embryonic dopaminergic neurones after transplantation." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624313.

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Pöltl, Dominik [Verfasser]. "Degeneration mechanisms in human dopaminergic neurons / Dominik Pöltl." Konstanz : Bibliothek der Universität Konstanz, 2012. http://d-nb.info/1025226135/34.

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Moubarak, Estelle. "Constraints imposed by morphological and biophysical properties of axon and dendrites on the electrical behaviour of rat substantia nigra pars compacta dopaminergic neurons." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0746.

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L’activité électrique des neurones est déterminée par des interactions complexes entre leurs propriétés morphologiques et biophysiques. Les neurones dopaminergiques (DA) de la substance noire compacte (SNc) présentent une caractéristique morphologique peu commune parmi les neurones de mammifères: leur axone émerge fréquemment d’une dendrite à une distance très variable du soma. Malgré cette importante variabilité dans la localisation de l’axone, peu d’articles ont étudié un lien potentiel entre morphologie neuronale et activité électrique dans ces cellules. Dans un premier article, nous avons
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Sousa, Kyle Matthew. "Nuclear receptor and Wnt function in developing dopaminergic neurons /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-105-0/.

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Books on the topic "Dopaminergic neurons"

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Umberto, Di Porzio, Pernas-Alonso Roberto, and Perrone-Capano Carla, eds. Development of dopaminergic neurons. R.G. Landes Co., 1999.

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Beart, P. M., G. N. Woodruff, and D. M. Jackson, eds. Pharmacology and Functional Regulation of Dopaminergic Neurons. Palgrave Macmillan UK, 1988. http://dx.doi.org/10.1007/978-1-349-10047-7.

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Giovanni, Giuseppe. Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra. Springer-Verlag Vienna, 2009.

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Giovanni, Giuseppe, Vincenzo Di Matteo, and Ennio Esposito, eds. Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-92660-4.

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Kjell, Fuxe, and Wenner-Grenska samfundet, eds. Trophic regulation of the basal ganglia: Focus on dopamine neurons. Pergamon, 1994.

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M, Beart P., Woodruff G. N, Jackson D. M, and International Congress of Pharmacology, (10th : 1987 : Sydney, N.S.W.), eds. Pharmacology and functional regulation of dopaminergic neurons: Proceedings of a satellite symposium of the IUPHAR 10th International Congress of pharmacology, 31 Aug.- 2 Sep. 1987. Macmillan, 1988.

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M, Beart P., Woodruff Geoffrey N, Jackson D. M, International Union of Pharmacology, and International Congress of Pharmacology (10th : 1987 : Cessnock, N.S.W.), eds. Pharmacology and functional regulation of dopaminergic neurons: Proceedings of a satellite symposium of the IUPHAR 10th International Congress of Pharmacology, 31 August-2 September 1987. Macmillan Press, Scientific & Medical, 1988.

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M, Beart P., Woodruff Geoffrey N, Jackson D. M, International Union of Pharmacology, and International Congress of Pharmacology (10th : 1987 : Cessnock, N.S.W.).)., eds. Pharmacology and functional regulation of dopaminergic neurons: Proceedings of a satellite symposium of the IUPHAR 10th International Congress of Pharmacology, 31 August-2 September 1987. PSG Pub. Co., 1988.

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W, Stone T., ed. CNS neurotransmitters and neuromodulators: Glutamate. CRC Press, 1995.

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Triarhou, Lazaros C. Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson’s Disease. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0699-7.

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Book chapters on the topic "Dopaminergic neurons"

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Kummer, W. "Are Chemoreceptor Neurons Dopaminergic?" In Chemoreceptors and Chemoreceptor Reflexes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-8938-5_14.

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Bartholini, G., B. Zivkovic, and B. Scatton. "Dopaminergic Neurons: Basic Aspects." In Catecholamines II. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73551-6_7.

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Markstein, R., J. M. Vigouret, A. Enz, D. Coward, A. Jaton, and U. Briner. "Dopaminergic Ergots." In Pharmacology and Functional Regulation of Dopaminergic Neurons. Palgrave Macmillan UK, 1988. http://dx.doi.org/10.1007/978-1-349-10047-7_4.

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Giovanni, Giuseppe. "A Diet for Dopaminergic Neurons?" In Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-92660-4_27.

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Jaeger, C. B. "Plasticity of Mesencephalic Dopaminergic Neurons." In Progress in Parkinson Research. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0759-4_19.

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Prediger, Rui Daniel, Mariza Bortolanza, Ana Carolina de Castro Issy, Bruno Lopes dos Santos, Elaine Del Bel, and Rita Raisman-Vozari. "Dopaminergic Neurons in Parkinson’s Disease." In Handbook of Neurotoxicity. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-5836-4_7.

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Diana, M., and J. M. Tepper. "Electrophysiological Pharmacology of Mesencephalic Dopaminergic Neurons." In Dopamine in the CNS II. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-06765-9_1.

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Tepper, James M., Pau Celada, Yuji Iribe, and Carlos A. Paladini. "Afferent Control of Nigral Dopaminergic Neurons." In Advances in Behavioral Biology. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0179-4_64.

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Smidt, Marten P., J. Peter, and H. Burbach. "Terminal Differentiation of Mesodiencephalic Dopaminergic Neurons:." In Advances in Experimental Medicine and Biology. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-0322-8_4.

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von Bohlen, Oliver, and Klaus Unsicker. "Neurotrophic Support of Midbrain Dopaminergic Neurons." In Advances in Experimental Medicine and Biology. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-0322-8_7.

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Conference papers on the topic "Dopaminergic neurons"

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Pitta, Marina Galdino da Rocha, Jordy Silva de Carvalho, Luzilene Pereira de Lima, and Ivan da Rocha Pitta. "iPSC therapies applied to rehabilitation in parkinson’s disease." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.022.

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Background: Parkinson’s disease (PD) is a neurological disorder that affects movement, mainly due to damage and degeneration of the nigrostriatal dopaminergic pathway. The diagnosis is made through a clinical neurological analysis where motor characteristics are considered. There is still no cure, and treatment strategies are focused on symptoms control. Cell replacement therapies emerge as an alternative. Objective: This review focused on current techniques of induced pluripotent stem cells (iPSCs). Methods: The search terms used were: “Parkinson’s Disease”, “Stem cells” and “iPSC”. Open arti
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Comerford, James P., Steve Perryman, Amy Pruszenski, Frank Thorn, and Richard Held. "Assessment of Lateral Interaction Across the Visual Field Using Hermann Grid Contrast Thresholds." In Vision Science and its Applications. Optica Publishing Group, 1997. http://dx.doi.org/10.1364/vsia.1997.sae.10.

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We have developed several psychophysical measures that may reflect the neuropharmacological control of center-surround interactions within the human visual system (Comerford et al 1990, 1991). We have been particularly interested in patients with Parkinson’s disease, a disease associated with destruction of the dopaminergic neurons of the Substantia Nigra (Comerford et al 1995). Recent evidence suggests that this disease also affects the dopaminergic neurons of the retina (Nguyen-Legros 1988). These retinal neurons release dopamine maximally under photopic conditions and are associated with an
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Prince, Akimul, and Biswanath Samanta. "Control of Autonomous Robots Using the Principles of Neuromodulation." In ASME 2013 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/dscc2013-4107.

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The paper presents a control approach based on vertebrate neuromodulation and its implementation on an autonomous robot platform. A simple neural network is used to model the neuromodulatory function for generating context based behavioral responses to sensory signals. The neural network incorporates three types of neurons — cholinergic and noradrenergic (ACh/NE) neurons for attention focusing and action selection, dopaminergic (DA) neurons for curiosity-seeking, and serotonergic (5-HT) neurons for risk aversion behavior. The implementation of the neuronal model on a relatively simple autonomo
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Alavi, Azadeh, Brenton Cavanagh, Gervase Tuxworth, Adrian Meedeniya, Alan Mackay-Sim, and Michael Blumenstein. "Automated classification of dopaminergic neurons in the rodent brain." In 2009 International Joint Conference on Neural Networks (IJCNN 2009 - Atlanta). IEEE, 2009. http://dx.doi.org/10.1109/ijcnn.2009.5178740.

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Lavrova, Alina, Mikhail Akimov, Viktor Blokhin, Natalia Gretskaya, and Vladimir Bezuglov. "NOVEL MULTIFUNCTIONAL COMPOUNDS FOR TARGETED DELIVERY TO DOPAMINERGIC NEURONS." In XVI International interdisciplinary congress "Neuroscience for Medicine and Psychology". LLC MAKS Press, 2020. http://dx.doi.org/10.29003/m1121.sudak.ns2020-16/291.

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Prince, Akimul, and Biswanath Samanta. "Neuromodulation Based Control of Autonomous Robots." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64049.

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The paper presents a control approach based on neuromodulation in vertebrate brains and its implementation on an autonomous robotic platform. The neuromodulatory function is modeled through a neural network for generating context based behavioral responses to sensory input signals from the environment. Three types of neurons are incorporated in the neural network model. The neurons are — cholinergic and noradrenergic (ACh/NE) for attention focusing and action selection, dopaminergic (DA) for curiosity-seeking, and serotonergic (5-HT) for risk aversion behaviors. The neuronal model was implemen
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Blankenship, Harris E., Kylie Handa, Willard M. Freeman, and Michael J. Beckstead. "Intrinsic Alterations of Dopaminergic Neurons in the 3xTg-Alzheimer’s Disease Mouse." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.552490.

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Besada, Christina, Stacia I. Lewandowski, and Ole Mortensen. "Bidirectional ERK1/2 Modulation in Dopaminergic Neurons Regulates DAT Expression and Function." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.166680.

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Muhammad, Cameron, and Biswanath Samanta. "Control of Autonomous Robots Using Principles of Neuromodulation in ROS Environment." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-38158.

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Decision making of a vertebrate in response to the sensory signals from the environment is regulated by the neuromodulatory systems in its brain. A vertebrate’s behaviors like focusing attention, cautious risk-aversion and curiosity-seeking exploration are influenced by these neuromodulators. The paper presents an autonomous robotic control approach based on vertebrate neuromodulation and its implementation on multiple open-source hardware platforms. A simple neural network is used to model the neuromodulatory functions for generating context based behavioral responses to sensory signals. The
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Souza, Caroline, Giovanni Viana, Bruno Coelho, Ana Beatriz Massaranduba, and Rodrigo Ramos. "Feature Extraction from EEG signals for detection of Parkinsons Disease." In Congresso Brasileiro de Inteligência Computacional. SBIC, 2024. http://dx.doi.org/10.21528/cbic2023-027.

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The Electroencephalogram (EEG) is a medical tool that captures, in a non-invasive way, electrical signals from the brain activities performed by neurons. EEG signals have been the target of study as a biomarker of Parkinsons disease (PD), where several methods of analysis are applied. The present work aims to evaluate features extracted from EEG signals, through methodologies such as HOS, Haralick descriptors, and Fractal Features, as new biomarkers for PD identification. Data from 50 individuals, available at the Open Neuro repository, who underwent an attentional cognitive task were analyzed
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Reports on the topic "Dopaminergic neurons"

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Surmeier, D. J. Calcium Homeostatasis and Mitochondrial Dysfunction in Dopaminergic Neurons of the Substantia Nigra. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada519458.

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Andrades, Oscar, David Ulloa, Dario Martinez, et al. Effect of the manipulation of the variables that configure the stimulus of strength training on motor symptoms in people with Parkinson's disease: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0079.

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Review question / Objective: To analyze the evidence on studies that have manipulated the variables that make up the strength training stimulus and its effects on motor symptoms in people with Parkinson's disease. Condition being studied: Parkinson's is a multisystemic neurodegenerative disease that affects the central nervous system and is caused by a loss of dopaminergic neurons in the compact part of the substantia nigra of the basal ganglia of the midbrain. People with Parkinson's disease (PEP) have non-motor and motor clinical symptoms. Classic motor symptoms are rest tremor, joint stiffn
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Wang, Xiao, Hong Shen, Yujie Liang, Yixin Wang, Meiqi Zhang, and Hongtao Ma. Effectiveness of Tango Intervention on Motor Symptoms in Patients with Parkinson's Disease: A Protocol for Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.5.0009.

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Review question / Objective: Parkinson's disease (PD) is a degenerative neurological disease caused by the loss of dopaminergic neurons in the pars compacta of the substantia nigra of the brain, resulting in lesions in the basal ganglia. The main motor symptoms of PD include resting tremor, rigidity, akinesia or bradykinesia and postural instability. As an exercise intervention based on musical accompaniment, tango dance has shown positive effects on the rehabilitation of motor symptoms in PD patients in recently. In this study, we systematically reviewed the efficacy of tango intervention in
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Singh, Ruchi, Akhiya Nail, and Nirendra Kumar Rai. Effectiveness of Vitamin B12 Supplementation on cognitive, motor & mood instability of Parkinson’s disease patients on levodopa treatment :A Systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.2.0066.

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Review question / Objective: The treatment of choice for patients of Parkinson's disease is levodopa. However, levodopa has been suggested to decrease Vit B12 level in these patients. Thus, the research question for this systematic review is whether vit B 12 supplementation in Parkinson's disease(PD) patients on treatment with levodopa improves vit B12 level effecting the Cognition, Motor functions and Mood instability among them in comparison to PD patients on levodopa treatment who are not supplemented with Vit B12. Condition being studied: Parkinson disease is the progressive degeneration o
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Zhang, Yu, Chaoliang Sun, Hengxi Xu, et al. Connectivity-Based Subtyping of De Novo Parkinson Disease: Biomarkers, Medication Effects and Longitudinal Progression. Progress in Neurobiology, 2024. http://dx.doi.org/10.60124/j.pneuro.2024.10.04.

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Parkinson's disease (PD) is characterized by divergent clinical symptoms and prognosis, suggesting the presence of distinct subtypes. Identifying these subtypes is crucial for understanding the underlying pathophysiology, predicting disease progression, and developing personalized treatments. In this study, we propose a connectivity-based subtyping approach, which measures each patient's deviation from the reference structural covariance networks established in healthy controls. Using data from the Parkinson's Progression Markers Initiative, we identified two distinct subtypes of de novo PD pa
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Przedborski, Serge E. Role of Nitric Oxide in MPTP Induced Dopaminergic Neuron. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada384796.

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Reinsvold, Josef. Neuron Glia Crosstalk In Dopaminergic Neurodegeneration in Parkinson's Disease. Iowa State University, 2021. http://dx.doi.org/10.31274/cc-20240624-1050.

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Przedborski, Serge E. Role of Nitric Oxide in MPTP-Induced Dopaminergic Neuron Degeneration. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada450371.

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Przedborski, Serge. Role of Nitric Oxide in MPTP-Induced Dopaminergic Neuron Degeneration. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada416386.

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Przedborski, Serge, and Vernice Jackson-Lewis. Role of Nitric Oxide in MPTP-Induced Dopaminergic Neuron Degeneration. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada420096.

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