Academic literature on the topic 'DRUGS LTD'

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Journal articles on the topic "DRUGS LTD"

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Sri, D. Soumya, and N. Uday Kumar. "Quality Of Work Life At Hetero Drugs Ltd." Think India 22, no. 3 (2019): 370–76. http://dx.doi.org/10.26643/think-india.v22i3.8265.

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Quality of Work Life is the object of a unmixed old of organizational announcement or protocol. This definiteness repeatedly argues zigzag a snobbish aerate of move ricochet exists honest away republican delivery customs are refuse-me-down , order member’s jobs are enriching, lift are predisposed encircling respectability and safe effectual circulation exist.
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Zaman, Muhammad H., and Tarun Khanna. "The Cost and Evolution of Quality at Cipla Ltd., 1935–2016." Business History Review 95, no. 2 (2021): 249–74. http://dx.doi.org/10.1017/s000768052000077x.

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This article examines the evolution of Indian pharmaceutical manufacturer Cipla toward producing drugs that met the quality standards of European and U.S. regulators. It employs new research in both Cipla's corporate archives and a wide range of oral histories. The article argues that, along with a long-standing corporate culture of self-reliance rooted in nationalism starting from the company's inception in 1935, major factors in Cipla's strategy from the 1960s through the early 2000s included the early adoption and continued use of quality-control technology, along with efforts to create glo
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Tanaka, E., E. Inoue, R. Sakai, I. Katsuhiko, A. Shoji, and M. Harigai. "POS0554 MEDICAL COST AND RESOURCE USE IN PATIENTS STARTING TREATMENT FOR RHEUMATOID ARTHRITIS TREATED WITH AND WITHOUT CORTICOSTEROIDS IN JAPAN." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 511.2–512. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2805.

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Background:The 2019 update of the European League Against Rheumatism (EULAR) treatment recommendations strongly recommends co-administration of corticosteroids (CSs) with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) in patients with RA as bridging therapy to improve the success rate of the first-line treatment and to avoid disease flare-ups1; however, current treatment guidelines for RA in Japan do not clearly mention about their use. Poor disease management after the initial diagnosis can affect the overall use of health services and the economic burden on patients.
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Tanaka, E., E. Inoue, R. Sakai, I. Katsuhiko, A. Shoji, and M. Harigai. "POS0551 MEDICAL COSTS FOR PATIENTS STARTING TREATMENT FOR RHEUMATOID ARTHRITIS WHO HAVE COMORBID DIABETES MELLITUS IN JAPAN." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 510.1–510. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2770.

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Background:Rheumatoid arthritis (RA) patients can experience various comorbidities1. The incidence of diabetes mellitus (DM) is reported higher in patients with RA2 and comorbid DM is likely to affect treatment outcomes3 and then healthcare resource uses, however, no previous study has not focused on it.Objectives:To evaluate medical costs and resource use in patients starting treatment for RA with and without DM using a large claims database in Japan.Methods:We used a large Japanese administrative claims database constructed by the Japan Medical Data Center (JMDC)4. Patients with the Internat
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Kojima, Yuki, Fumihiko Hayakawa, Takanobu Morishita, et al. "YM155 Induces Apoptosis through Proteasome-Dependent Degradation of MCL-1 in Primary Effusion Lymphoma." Blood 128, no. 22 (2016): 3013. http://dx.doi.org/10.1182/blood.v128.22.3013.3013.

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Abstract Primary effusion lymphoma (PEL) is a subtype of non-Hodgkin lymphoma caused by human herpes virus 8 (HHV-8), which mainly occurs in patients with acquired immunodeficiency. It is highly refractory to conventional chemotherapies, and has a very poor prognosis. We recently developed patient-derived xenograft (PDX) screening, a novel high-throughput drug screening system using PDX cells that were established by transplantations of primary tumor cells into immunodeficient mice and maintained primary cell phenotype. PDX screening is expected to discover anti-tumor drugs that have been over
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Thomas, Mark J., and Robert C. Malenka. "Synaptic plasticity in the mesolimbic dopamine system." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 358, no. 1432 (2003): 815–19. http://dx.doi.org/10.1098/rstb.2002.1236.

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Long-term potentiation (LTP) and long-term depression (LTD) are thought to be critical mechanisms that contribute to the neural circuit modifications that mediate all forms of experience-dependent plasticity. It has, however, been difficult to demonstrate directly that experience causes long-lasting changes in synaptic strength and that these mediate changes in behaviour. To address these potential functional roles of LTP and LTD, we have taken advantage of the powerful in vivo effects of drugs of abuse that exert their behavioural effects in large part by acting in the nucleus accumbens (NAc)
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Higuchi, T., E. Tanaka, E. Inoue, et al. "AB0286 RETENTION RATE OF BIOLOGIC DISEASE-MODIFYING ANTI-RHEUMATIC DRUGS IN PATIENTS WITH RHEUMATOID ARTHRITIS WITH DECREASED KIDNEY FUNCTION: RESULTS FROM THE IORRA COHORT." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1324. http://dx.doi.org/10.1136/annrheumdis-2023-eular.374.

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BackgroundWe previously reported that rheumatoid arthritis (RA) patients with chronic kidney disease (CKD) were at increased risk of failure to achieve remission and of occurrence of hospitalized infections [1]. Although biologic disease-modifying anti-rheumatic drugs (bDMARDs) are a promising treatment option, their effectiveness and safety for this population have not been fully evaluated to date.ObjectivesTo determine the optimal bDMARD selection for treatment of RA patients with decreased kidney function, we compared the retention rates of patients receiving tumor necrosis factor inhibitor
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Wright, W. B. "Drugs, ageing, and society Burns Bruce Phillipson Chris Drugs, ageing, and society Croom Helm Ltd, Beckenham, 1986, 180pp, H/B, £19.95." Elderly Care 7, no. 4 (1987): 28. http://dx.doi.org/10.7748/eldc.7.4.28.s27.

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Saliy, O. O., and M. O. Sinchuk. "DEVELOPMENT OF APPROACHES TO LABORATORY CONTROL OF «BIOTESTLAB» LTD TO ENSURE QUALITY OF VETERINARY PREPARATIONS." Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology 22, no. 2 (2021): 331–38. http://dx.doi.org/10.36359/scivp.2021-22-2.39.

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The article presents the development of approaches to laboratory control and the results of research related to the standardization of methods at Ltd "BIOTESTLAB" to ensure the quality of veterinary drugs. Attention is paid to the methods of biological quality control of veterinary drugs: microbiological purity, hemagglutination reaction (HAR), determination of infectious activity of embryonic vaccines. Because such methods are characterized by low automation, low accuracy, the impact on the result of error due to personnel performing operations manually, the lack of regulatory approaches to v
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Derkach, I. "Сучасні тенденції на вітчизняному ринку ферумвмісних препаратів для тварин". Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 19, № 78 (2017): 23–25. http://dx.doi.org/10.15421/nvlvet7805.

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The article presents an analysis of the domestic market of veterinary preparations of Ferum. It is established that nowadays it is represented by 13 drugs of the following group: QV03A Antianemic agents. Preparations of iron, according to ATS-vet classification. Assortment of 38% is provided by pharmaceutical goods of Ukrainian producers: «O.L.KAR-AgroZoOvetService», PP Farmaton, LLC «BROVAFARMA», Ltd. «Research and experimental production Institute of Epizootology», PP «BIOFARM», LLC «Vetsintez». Imported products (62%) are presented by Pharmacosmos A/S (Kingdom Denmark), MERIEL, KOOFAVET C.A
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Dissertations / Theses on the topic "DRUGS LTD"

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Siff, Stephen I. "Glossy Visions: Coverage of LSD in Popular Magazines, 1954-1968." View abstract, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3338743.

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Dyck, Erika Wright David. "Psychedelic psychiatry: LSD and post-World War II medical experimentation in Canada /." *McMaster only, 2005.

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Wong, Lai-har Teresa. "Drug dependency and the experience of young offenders in a residential drug treatment institution." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20621905.

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Šmitaitė, Eglė. "Narkomano kelias: nuo pirmosios dozės iki apsisprendimo gyventi be narkotikų." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2007~D_20140623_172400-12108.

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SANTRAUKA Narkomanija – opi ir sunkiai išsprendžiama visuomenės problema, kurios sprendimui būtini įvairūs tyrimai ir analizė. Šiame darbe nagrinėjamas narkomano kelias nuo pirmosios dozės iki apsisprendimo gyventi be narkotikų. Siekiant išsamiai atskleisti šį kelią, darbe aptariamos pagrindinės narkotinių medžiagų savybės, remiantis įvairių autorių požiūriais perteikiama narkomanijos samprata, ją sąlygojantys veiksniai, analizuojami subkultūros bruožai ir atskleidžiama narkomanijos prevencijos reikšmė. Narkotinių medžiagų vartojimas nėra priimtina ir toleruojama elgesio norma, todėl narkomani
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Šiaudkulytė, Ieva. "Augalinių preparatų asortimento kitimo tendencijos Lietuvos vaistinėse." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140630_133822-20854.

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Lietuvoje daugiausiai buvo užregistruota virškinimo sistemą veikiančių augalinės kilmės preparatų. Dažniausiai registruojamos augalinių vaistinių preparatų vaistų formos yra tabletės, lašai, tirpalai bei arbatos. Tarp augalinių preparatų Lietuvos vaistų registre vyrauja savo produkciją įregistravusios Lietuvos, Vokietijos bei Lenkijos įmonės. Tarp įmonių įregistravusių savo produkciją lyderiauja Lietuvos įmonės „Acorus Calamus“, „Švenčionių vaistažolės“, Lenkijos įmonė „Herbapol“ (iki 2000m.) bei Lietuvos įmonė „Valentis“ (2010m. ir 2013m.).<br>1994 – 2013 there were mainly registered drugs fo
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Jenvey, Michelle Catherine. "Structure led drug design for the pentraxins." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439382.

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Walker, Alex J. "Anti-cancer actions in commonly used drugs : epidemiology led by laboratory science." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/12205/.

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Despite considerable research on cancer treatments and preventatives, poor outcomes in cancer patients are common. The vital search for effective cancer drugs often begins in the laboratory, where unfortunately the effects of a drug in humans cannot be perfectly modelled. Epidemiology can play a vital role in determining the real world efficacy of a drug currently used for other purposes before clinical trials begin. This thesis therefore used primarily laboratory evidence to identify potential anti-cancer uses for existing common drugs. The drugs and cancers studied were; tricyclic antidepres
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Schooler, Edward Webb. "The War on Drugs in Latin America: How Misinterpretation Led to Failed Policy." Scholarship @ Claremont, 2012. http://scholarship.claremont.edu/cmc_theses/403.

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The War on Drugs in Latin America: How Misinterpretation Led to Failed Policy investigates how and why United States counternarcotics policy failed abroad, specifically in the northern Andean region. This work examines the entire history of the US waged War on Drugs abroad beginning with President Richard M. Nixon and concluding with current President Barack Obama. After this thorough examination alternative counternarcotics policies are examined.
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Delmanto, Júlio. "História social do LSD no Brasil: os primeiros usos medicinais e o começo da repressão." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/8/8138/tde-11122018-161707/.

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Depois de apresentar as origens históricas da contracultura, no Brasil e nos Estados Unidos, e contextualizar um pouco das relações entre os integrantes destes movimentos e o uso de drogas, sobretudo maconha e ácido lisérgico, esse trabalho traça, através principalmente da análise de trajetórias individuais que se cruzam de uma forma ou de outra, uma história social da chegada do LSD ao Brasil. O trabalho investiga, com profundidade, o primeiro processo judicial por tráfico e porte da substância, iniciado em janeiro de 1970, em São Paulo, estudando a trajetória dos principais réus, a repercuss
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Virbalis, Jonas. "Narkotikų vartojimas ir prevencija mokykloje: mokinių, mokytojų, tėvų ir policijos pareigūnų vertinimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140905_092334-44320.

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Darbo tema. Pastaraisiais metais vis dažniau susiduriama su narkomanijos problema, narkotikų paplitimu ir jų vartojimu jaunimo tarpe. Tai glaudžiai susiję su kitomis socialinėmis problemomis – smurtu, patyčiomis, savižudybėmis, nusikalstamumu. Nepaisant to, kad problema plačiai nagrinėjama globaliu mastu, reikia ieškoti atsakymų į klausimus: kodėl narkotikų paplitimas sparčiai didėja, kokiose socialinėse terpėse labiausiai vyrauja, kokios prevencinės priemonės yra taikomos, kaip jos veikia. Verta pabrėžti, kad būtent mokykloje moksleiviai susiduria su daugeliu socialinių veiksnių ir problemų:
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Books on the topic "DRUGS LTD"

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India. Parliament. Committee on Public Undertakings. Indian Drugs and Pharmaceuticals Ltd. (Ministry of Commerce). Lok Sabha Secretariat, 1988.

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Littell, Mary Ann. LSD. Enslow Publishers, 1996.

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Phillips, Jane Ellen. LSD, PCP & other hallucinogens. Chelsea House Publishers, 2000.

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Algeo, Philippa. Acid and hallucinogens. F. Watts, 1990.

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1917-, Pletscher A., Ladewig Dieter 1938-, and Schweizerische Akademie der Medizinischen Wissenschaften. Symposium, eds. 50 years of LSD: Current status and perspectives of hallucinogens : a symposium of the Swiss Academy of Medical Sciences, Lugano-Agno (Switzerland), October 21 and 22, 1993. Parthenon Pub. Group, 1994.

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Hofmann, Albert. Tun und Lassen: Essays, Gedanken und Gedichte. Nachtschatten Verlag, 2011.

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Delmanto, Júlio. História social do LSD no Brasil: Os primeiros usos medicinais e o começo da repressão. Editora Elefante, 2020.

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Arap, Fauzi. Mare nostrum: Sonhos, viagens e outros caminhos. Editora SENAC São Paulo, 1998.

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Masters, Robert E. L. The varieties of psychedelic experience: The classic guide to the effects of LSD on the human psyche. Park Street Press, 2000.

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H, Blum Richard, ed. Utopiates. AldineTransaction, 2009.

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Book chapters on the topic "DRUGS LTD"

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Vervaeke, Hylke. "Tripmiddelen: lsd en psychedelische paddenstoelen." In Drugs en alcohol; Gebruik, misbruik en verslaving. Bohn Stafleu van Loghum, 2008. http://dx.doi.org/10.1007/978-90-313-6554-8_11.

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Jennewein, H. M., R. Anderskewitz, C. J. Meade, M. Pairet, and F. Birke. "LTB4 Antagonism." In New Drugs for Asthma, Allergy and COPD. KARGER, 2001. http://dx.doi.org/10.1159/000062146.

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Freye, Enno. "LSD, a Semisynthetic Psychedelic Drug." In Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs. Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2448-0_39.

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Parrott, A. C. "MDMA and LSD." In Drug Abuse and Addiction in Medical Illness. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-3375-0_13.

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Clark, Christopher E. "Nurse Led Interventions in Hypertension." In Drug Adherence in Hypertension and Cardiovascular Protection. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-76593-8_18.

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Cruz-Santiago, Arely. "Lists, Maps, and Bones: The Untold Journeys of Citizen-led Forensics in Mexico." In Beyond Drugs, Smuggling and Trafficking. Routledge, 2021. http://dx.doi.org/10.4324/9781003152330-5.

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Cavanagh, Julien J., and Teresa Y. Smith. "Psychedelic Drug (LSD, PCP, Hallucinogenic Mushrooms) Intoxication." In Quick Guide to Psychiatric Emergencies. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58260-3_36.

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Thomas, Mark J., and Robert C. Malenka. "Synaptic plasticity in the mesolimbic dopamine system." In Long-term Potentiation: Enhancing Neuroscience for 30 years. Oxford University PressOxford, 2004. http://dx.doi.org/10.1093/oso/9780198530305.003.0027.

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Abstract Long-term potentiation (LTP) and long-term depression (LTD) are thought to be critical mechanisms that contribute to the neural circuit modifications that mediate all forms of experience-dependent plasticity. It has, however, been difficult to demonstrate directly that experience causes long-lasting changes in synaptic strength and that these mediate changes in behaviour. To address these potential functional roles of LTP and LTD, we have taken advantage of the powerful in vivo effects of drugs of abuse that exert their behavioural effects in large part by acting in the nucleus accumb
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Valter, Karel, and Philippe Arrizabalaga. "LSD Analogues." In Designer Drugs Directory. Elsevier, 1998. http://dx.doi.org/10.1016/b978-044420525-4/50063-2.

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C. Cardoso, Nicole, Carel B. Oosthuizen, Nashied Peton, and Vinayak Singh. "Drug Repurposing for Tuberculosis." In Drug Repurposing - Molecular Aspects and Therapeutic Applications [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.101393.

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Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a major global health concern given the increase in multiple forms of drug-resistant TB. This underscores the importance of a continuous pipeline of new anti-TB agents. From recent studies, it is evident that the increase in drug efficacy is being achieved through re-engineering old TB-drug families and repurposing known drugs. This approach has led to producing a newer class of compounds which not only saves time and investment in developing newer drugs but is also effective in identifying drug candidates with novel mechanisms to tre
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Conference papers on the topic "DRUGS LTD"

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Nyarko, Savanna, Moses J. Eghan, and Elvis K. Tiburu. "LTA zeolites synthesized at different temperatures and evaluating the drug loading capability." In Plasmonics: Design, Materials, Fabrication, Characterization, and Applications XXII, edited by Yu-Jung Lu and Takuo Tanaka. SPIE, 2024. http://dx.doi.org/10.1117/12.3026507.

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Ngonyoza, Ntsikelelo, Abdulaziz Al Hamdi, Aliaa Al Balushi, and Robin Blakey. "Failure of a Residue Fluid Catalytic Cracker (RFCC) Catalyst Cooler’s Aeration Piping System (Cat Cooler Internals)." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-11086.

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Abstract This paper explores the various degradation mechanisms experienced by a refinery’s RFCC catalyst cooler aeration piping system. A detailed analysis of the most recent failure and a past failure was conducted to determine the various metallurgical and mechanical degradation mechanism(s) that led to these failures. The analysis which covered both the old UNS S30409, TP304H stainless steel, and newly upgraded UNS S34709, TP347H stainless steel catalyst cooler aeration piping system, with the same design, showed the dominant degradation mechanisms to be low cycle thermal fatigue and low c
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Otte, Lennart B., Christer Hogstrand, Adil Mardinoglu, and Miao Guo. "Multi-Omics biological embeddings for ML-models." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.136974.

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Machine learning algorithms have led to the development of numerous vector embeddings for biological entities such as metabolites, proteins, genes, and enzymes. However, these embeddings often lack contextual information due to their specialized focus on individual omics. Disease progression and biosynthesis pathways are increasingly understood through complex, multi-layered networks that integrate diverse omics data and intricate signaling and reaction sequences. Capturing these relationships in a meaningful way requires embeddings that account for both functional and multi-modal dependencies
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Fahal, AH, ES Ahmed, SM Bakhiet, et al. "Once-weekly repurposed fosravuconazole versus daily itraconazole, with surgery, in patients with eumycetoma in Sudan: a randomised, double-blind, phase 2, proof-of-concept superiority trial." In MSF Scientific Days International 2024. MSF-USA, 2024. http://dx.doi.org/10.57740/jznxuiaji7.

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INTRODUCTION Treatment options for the highly neglected fungal tropical disease eumycetoma are limited and poorly adapted to patients’ contexts, with surgery often required. The first-line treatment, itraconazole, thought to be 40% effective, must be taken twice daily for ≥12 months with food, making adherence difficult. An effective, affordable, context-appropriate treatment is urgently needed. The Drugs for Neglected Diseases Initiative (DNDi) repurposed the broad-spectrum antifungal agent fosravuconazole, developed by Eisai Ltd for onychomycosis. We aimed to compare two different doses of w
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Suryakrishna, S. S., K. Praveen, S. Tamilselvan, and S. Srinath. "IoT Based Automation and Blockchain for Medical Drug Storage and Smart Drug Store." In Intelligent Computing and Technologies Conference. AIJR Publisher, 2021. http://dx.doi.org/10.21467/proceedings.115.8.

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The increase in the work stress and decrease in the time for oneself has led to the rise in the dependency on the medicines and drugs. The drugs and medicines are the key sources for saving the human life when the patient is in the danger. In order to maintain regular and quality supply of the drugs and medicines has to monitor on the regular basis. There are numerous medicines and drugs brought in the store but usually drugs and medicines are stolen to satisfy one’s greed, get expired or placed at unknown locations in the store. So to prevent such situation and saving the life of the patient
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Koç, Erdem. "Anti-Drug Strategies and the Experience of the Counter Narcotics Department of Türkiye." In Panel on "Effective Drug Control Strategies in Northern Cyprus: Challenges and Opportunities in 2024". Emanate Publishing House Ltd., 2024. http://dx.doi.org/10.70020/ehass.2024.7.7.

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In recent years the emergence of synthetic drugs called NPS (New Psychoactive Substances) along with the traditional drugs, drug abuse and addiction have become a global problem. To conduct an effective and successful fight against this devastating problem, a common understanding is necessary among all relevant institutions and organizations. Türkiye has significant experience in the fight against drugs due to its geographical location and its multi-dimensional approach. The global nature of this problem necessitates the creation of international ties which are vital to not only access best pr
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Kamali, Reza, and Gholamreza Keshavarzi. "Computational Simulation of Magnetic Drug Targeting in Human Body." In ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2011. http://dx.doi.org/10.1115/icnmm2011-58115.

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Development of novel particle carrier methods has led to enhanced advances in targeted drug delivery. This paper has aimed the investigation of targeting drugs via attached magnetic particles into human body. This goal was approached by inducing a magnetic field near a specific part of the human body to target the drug or as it is called magnetic drug targeting (MDT). Blood flow and magnetic particles are simulated under the presence of the specified properties of a magnetic field. In order to demonstrate a more realistic simulation, the flow was considered pulsatile. Finally, the results prov
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Ibragimova, M. K., M. Tsyganov, and N. V. Litvyakov. "THE BASIS OF MOLECULAR GENETIC CLASSIFICATION OF BREAST TUMORS WITH A TRIPLE NEGATIVE PHENOTYPE." In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-44.

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Current knowledge of the genetic heterogeneity of the most aggressive molecular subtype of breast cancer (BC) - triple negative (TN) - has led to promising discoveries in drug treatment, including the use of DNA-damaging agents (platinum drugs and PARP inhibitors) in these tumors, as well as current use of immunotherapy.&#x0D; Of greatest importance is the ability to prescribe optimal drug treatment regimens to patients with TN in breast cancer, based on knowledge of the molecular genetic characteristics of this subtype of breast cancer, which will ultimately allow achieving high rates of over
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Magubane, Ntokozo, Malebogo Ngoepe, and Sudesh Sivarasu. "Design, Verification and Validation of a Dynamic Model for an Intramuscular Autoinjector." In 2024 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2024. http://dx.doi.org/10.1115/dmd2024-1028.

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Abstract The development of new injectable molecules for different diseases and reformation of first-generation pharmaceuticals has led to growing interest in making autoinjectors usable for different medications. The major challenge in this quest is the complexity of injecting highly viscous drugs in large volumes. This research aims to develop a dynamic model to describe the influence of drug viscosity and volume on the injection process and evaluate the sensitivity of medication fluid behaviour to variations in component dimensions of the autoinjector fluid delivery system. Using mathematic
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Mendoza, Hector, Victor G. Figueroa, Walter Gill, and Scott Sanborn. "Determining Airborne Release Fraction From DOT 7A Drums Exposed to a Thermal Insult." In 2020 International Conference on Nuclear Engineering collocated with the ASME 2020 Power Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/icone2020-16755.

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Abstract Fire suppression systems for transuranic (TRU) waste facilities are designed to minimize radioactive material release to the public and to facility employees in the event of a fire. Currently, facilities with Department of Transportation (DOT) 7A drums filled with TRU waste follow guidelines that assume a fraction of the drums experience lid ejection in case of a fire. This lid loss is assumed to result in significant TRU waste material from the drum experiencing an unconfined burn during the fire, and fire suppression systems are thus designed to respond and mitigate potential radioa
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Reports on the topic "DRUGS LTD"

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Borch, Thomas, Yitzhak Hadar, and Tamara Polubesova. Environmental fate of antiepileptic drugs and their metabolites: Biodegradation, complexation, and photodegradation. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597927.bard.

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Many pharmaceutical compounds are active at very low doses, and a portion of them regularly enters municipal sewage systems and wastewater-treatment plants following use, where they often do not fully degrade. Two such compounds, CBZ and LTG, have been detected in wastewater effluents, surface waters, drinking water, and irrigation water, where they pose a risk to the environment and the food supply. These compounds are expected to interact with organic matter in the environment, but little is known about the effect of such interactions on their environmental fate and transport. The original o
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Peng, Ciyan, Jing Chen, Sini Li, and Jianhe Li. Comparative Efficacy of Chinese Herbal Injections Combined Western medicine for Non-small cell lung cancer: A Bayesian Network Meta-Analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.11.0068.

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Review question / Objective: Advanced lung cancer has become the top malignant tumor in terms of morbidity and mortality, and Chinese herbal injections combined with western drugs have been widely used to treat advanced non-small cell lung cancer. For this purpose, we conducted a Bayesian network analysis to systematically evaluate the efficacy of different herbal injections combined with western drugs in the treatment of NSCLC. Subjects: Patients diagnosed with NSCLC by pathological or cytological examination, locally advanced or those who refused surgical treatment were included, regardless
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Biazus-Dalcin, Camila, Louise Marryat, Sarah Gray, et al. My data: an animated film, co-produced with people who use drugs. University of Dundee, 2023. http://dx.doi.org/10.20933/100001299.

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This video was co-produced with people on their drug use recovery journey to explore the perceptions of administrative data use for research and to share this information with the wider community. This work was led by members of the Substance Use Research Group (SURG), School of Health Sciences, University of Dundee. This project was funded by Research Data Scotland (RDS), https://www.researchdata.scot/ A film by: Craig Glencross, David Hood, Jade Renton, Maxine Thomson, Ryan Westwood, Stewart Bernard, Sarah Hulin, Robert Doig, Ashley McMaihin and everyone at Restoration Fife who shared their
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Tengamnuay, Parkpoom, Achariya Sailasuta, and Garnpimol C. Ritthidej. Efficacy and mechanistic studies of chitosan as nasal absorption enhancer of peptide drugs. Chulalongkorn University, 1998. https://doi.org/10.58837/chula.res.1998.21.

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Objective: To evaluate the safety and efficacy of chitosan (CS) as nasal absorption enhances of peptides. Methods: Two types of chitosans, i.e. CS J (free amine chitosan) and CD G (water-soluble glutamate salt), were evaluate for their masal absorption enhancing effectd on L-Tyr-D-Arg([D-Arg[square]]-Kyotorphic), an enzymatically stable dipeptide, using an in situ rat nasal perfusion technique. The two chitosans were subsequently studies for their possible membrane damaging effects based on measurements of releases mucosal components and histological evaluation. Results: At 0.5% w/v, both CS J
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van Dam, Johannes, and Sherry Hutchinson. Access to treatment for HIV/AIDS: Report of a meeting of international experts. Population Council, 2002. http://dx.doi.org/10.31899/hiv2002.1000.

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As of December 2001, the number of people living with HIV/AIDS is estimated at 40 million, and most live in the developing world. Advances in the development and availability of antiretroviral (ARV) drugs have led to a paradigm shift in most of the industrialized world, where highly active ARV therapy has resulted in a significant reduction in the prevalence of AIDS-related morbidity and mortality. In most of the developing world, however, the focus of national programs and international support continues to be on prevention and care in the absence of ARV treatment. While the moral imperative
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Homberg, Marloes, Robrecht Knapen, Kobe Jans, et al. Post Procedural Pain Following Percutaneous Thermal Liver Tumor Ablation under Procedural Sedation and Analgesia: A Single Center Retrospective Cohort Study. Science Repository, 2024. http://dx.doi.org/10.31487/j.acr.2024.01.02.sup.

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Background and Objectives: The incidence of post-procedural pain following percutaneous thermal liver ablation under procedural sedation and analgesia (PSA) is yet largely unknown. Only a few small studies investigated tumor and ablation factors on pain, whereas psychological or PSA factors as possible predictors for pain were not investigated. The primary aim of the current study is to measure the prevalence and severity of post-procedural pain based on maximal NRS. Secondary aim of this study is to identify predictors for post procedural pain post liver ablation under PSA. Methods: This sing
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Homberg, Marloes, Robrecht Knapen, Kobe Jans, et al. Post Procedural Pain Following Percutaneous Thermal Liver Tumor Ablation under Procedural Sedation and Analgesia: A Single Center Retrospective Cohort Study. Science Repository, 2024. http://dx.doi.org/10.31487/j.acr.2024.01.02.

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Background and Objectives: The incidence of post-procedural pain following percutaneous thermal liver ablation under procedural sedation and analgesia (PSA) is yet largely unknown. Only a few small studies investigated tumor and ablation factors on pain, whereas psychological or PSA factors as possible predictors for pain were not investigated. The primary aim of the current study is to measure the prevalence and severity of post-procedural pain based on maximal NRS. Secondary aim of this study is to identify predictors for post procedural pain post liver ablation under PSA. Methods: This sing
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Lehotay, Steven J., and Aviv Amirav. Ultra-Fast Methods and Instrumentation for the Analysis of Hazardous Chemicals in the Food Supply. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7699852.bard.

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Original proposal objectives: Our main original goal was to develop ultra-fast methods and instrumentation for the analysis of hazardous chemicals in the food supply. We proposed to extend the QuEChERS approach to veterinary drugs and other contaminants, and conduct fast and ultra-fast analyses using novel 5MB-MS instrumentation, ideally with real samples. Background to the topic: The international trade of agricultural food products is a $1.2 trill ion annual market and growing. Food safety is essential to human health, and chemical residue limits are legislated nationally and internationally
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Khongchareonporn, Nanthika, Songchan Puthong, Anumart Buakeaw, Kittinan Komolpis, and Umaporn Pimpitak. Production of monoclonal antibody against oxytetracycline for developing enzyme-linked immunosorbent assay (ELISA) test kit, 2nd year. Chulalongkorn University, 2015. https://doi.org/10.58837/chula.res.2015.100.

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In Thailand, oxytetracyline (OTC) has been used in the protection and treatment of infected shrimps. The misuse of OTC could lead to OTC residues in shrimps destined for consumption. To prevent consumers from exposure to drug residues and increase of drug resistance pathogens, several food safety authorities in many countries have set the maximum residue limits (MRLs) for OTC and enforced the surveillance detection programs. Therefore, an effective screening method is essential to detect OTC residue in food. Enzyme-linked immunosorbent assay (ELISA) is the suitable methods for screening a larg
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Stall, Nathan M., Kevin A. Brown, Antonina Maltsev, et al. COVID-19 and Ontario’s Long-Term Care Homes. Ontario COVID-19 Science Advisory Table, 2021. http://dx.doi.org/10.47326/ocsat.2021.02.07.1.0.

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Key Message Ontario long-term care (LTC) home residents have experienced disproportionately high morbidity and mortality, both from COVID-19 and from the conditions associated with the COVID-19 pandemic. There are several measures that could be effective in preventing COVID-19 outbreaks, hospitalizations, and deaths in Ontario’s LTC homes, if implemented. First, temporary staffing could be minimized by improving staff working conditions. Second, homes could be further decrowded by a continued disallowance of three- and four-resident rooms and additional temporary housing for the most crowded h
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