Academic literature on the topic 'Dysbiotic changes'

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Journal articles on the topic "Dysbiotic changes"

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Bobyr, V. V., V. A. Poniatovskyi, A. P. Chobotar, et al. "Features of structural-morphological changes in cases of experimental intestinal antibiotic-induced dysbiosis." Reports of Morphology 24, no. 3 (2018): 26–31. http://dx.doi.org/10.31393/morphology-journal-2018-24(3)-04.

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Nowadays, scientists often define dysbiosis as a condition of a microbial ecological system, in which there is a simultaneous abnormality of the functions and interaction mechanisms of its key components: macroorganism and indigenous microbiota associated with the mucous membranes of cavities and skin. At the same time, obviously, the basis of all these processes is changes of structural intestinal components that are caused by qualitative and quantitative changes in the normal microflora. Purpose: to study the ultrastructural organization of the mucous membrane of the small intestine of mice
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Nikolaeva, Nina V., Elizaveta V. Afanasievskaya, Eduard S. Gorovitz, and Alexander Ja Perevalov. "Intestinal microbiocinosis status as a criterion for nutritional quality assessment." Вестник Пермского университета. Серия «Биология»=Bulletin of Perm University. Biology, no. 2 (2022): 137–42. http://dx.doi.org/10.17072/1994-9952-2022-2-137-142.

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As a result of dynamic triple bacteriological examination for intestinal dysbiosis performed in 30 generally healthy 1st-year students who came to study from other regions, it was found that changes in the regime and quality of food led to the development of intestinal dysbiosis in 61.54% (out of 28 examined individuals) of nonresident first-year university students six months after the start of the study. The dysbiotic disorders of the intestinal microbiota were found to be primarily associated with a decrease (by 1‒3 orders of magnitude) in the titer of obligate bacteria (bifido- and lactic
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Tarasova, E., E. Yermolenko, V. Donets, et al. "The influence of probiotic Enterococcus faecium strain L5 on the microbiota and cytokines expression in rats with dysbiosis induced by antibiotics." Beneficial Microbes 1, no. 3 (2010): 265–70. http://dx.doi.org/10.3920/bm2010.0008.

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The animal model of intestinal dysbiosis induced by antibiotics was created. Dysbiotic condition was confirmed by the changes in titre of the indigenous microbiota (excessive growth of opportunistic microorganisms and reduced number of lactobacilli, bifidobacteria and enterococci) and the appearance of dyspeptic symptoms. Consumption of the fermented milk product with probiotic strain Enterococcus faecium L5 led to the rapid disappearance of dysbiosis symptoms, normalisation of the microbiota, increase in expression of IL-10 and decrease in IL-8 expression.
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Kamer, Angela R., Smruti Pushalkar, Babak Hamidi, et al. "Periodontal Inflammation and Dysbiosis Relate to Microbial Changes in the Gut." Microorganisms 12, no. 6 (2024): 1225. http://dx.doi.org/10.3390/microorganisms12061225.

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Periodontal disease (PerioD) is a chronic inflammatory disease of dysbiotic etiology. Animal models and few human data showed a relationship between oral bacteria and gut dysbiosis. However, the effect of periodontal inflammation and subgingival dysbiosis on the gut is unknown. We hypothesized that periodontal inflammation and its associated subgingival dysbiosis contribute to gut dysbiosis even in subjects free of known gut disorders. We evaluated and compared elderly subjects with Low and High periodontal inflammation (assessed by Periodontal Inflamed Surface Area (PISA)) for stool and subgi
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Zakharenko, A. A., A. N. Suvorov, I. V. Shlyk, et al. "DISORDERS OF A MICROBIOCENOSIS OF INTESTINES AT PATIENTS WITH A COLORECTAL CANCER AND WAYS OF THEIR CORRECTION (review)." Koloproktologia, no. 2 (June 30, 2016): 48–56. http://dx.doi.org/10.33878/2073-7556-2016-0-2-48-56.

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Patients with colorectal cancer in the perioperative period, revealed pronounced changes of microbiocenosis of colon, which is characterized by changes in the quantitative and qualitative composition of microflora. It showed a significant inhibition of anaerobic microbial component mainly bifidobacteria and lactobacilli. As a result, saprophytic microbes multiply with highly resistant to drugs, acquire pathogenic properties. The most prominent representative of such microorganisms is a pathogenic strain of Clostridium difficile, often provokes the development of pseudomembranous colitis. Depen
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Chervinets, V. M., Yu V. Chervinets, D. V. Ganzya, V. S. Belyaev, and V. S. Zaitseva. "The effect of the intestinal microbiota on the development of diabetes mellitus." Experimental and Clinical Gastroenterology, no. 12 (December 18, 2023): 77–85. http://dx.doi.org/10.31146/1682-8658-ecg-220-12-77-85.

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The aim of the study was to identify the pathogenetic role of intestinal microflora in the development of diabetes mellitus. The review presents data on the peculiarities of the development of the intestinal microflora (MC), factors that determine the occurrence of dysbiosis, as well as the effect of dysbiotic changes in MC on the pathogenesis of various types of diabetes mellitus. The role of MC in the occurrence of insulin resistance, as well as the metabolism of peptides that determine eating behavior, has been studied. The contribution of short-chain fatty acids produced by microorganisms
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Bezmenko, Alexandr A., and Natalya D. Sadovaya. "Vaginal and intestinal microbiocenosis composition in pregnant women." Journal of obstetrics and women's diseases 68, no. 6 (2020): 29–36. http://dx.doi.org/10.17816/jowd68629-36.

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Hypothesis/aims of study. It is assumed that intestinal dysbiosis, as well as bacterial vaginosis, may be one of the risk factors, and in some cases, the direct cause of pregnancy complications. This study was aimed to assess the intestinal and vaginal microbiocenosis composition in women with threatened miscarriage and normal pregnancy.
 Study design, materials and methods. The study involved 68 women aged 18 to 35 years (mean age 27.6 0.7 years) in pregnancy from 6 to 18 weeks. The main group consisted of 38 women with threatened miscarriage. The control group included women (n = 30) wi
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Barendregt, D., R. Gacesa, N. Plomp, et al. "P0123 The immune system of patients with immune-mediated diseases perceives dysbiotic intestinal microbial species, and IgG reactivity uncovers shared and non-shared responses across diseases." Journal of Crohn's and Colitis 19, Supplement_1 (2025): i505. https://doi.org/10.1093/ecco-jcc/jjae190.0297.

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Abstract Background Immune-mediated diseases (IMIDs), like Crohn’s disease (CD), ulcerative colitis (UC), psoriatic arthritis (PsA) and type I diabetes (T1D), have common features, including intestinal microbial dysbiosis. However, it is unclear whether dysbiosis contributes to IMID pathogenesis and whether the host immune system perceives dysbiotic commensals. In CD, high IgG and T-cell responses to Lachnospiraceae-derived flagellins associate with complex disease, while Lachnospiraceae fecal abundance is decreased in CD, suggesting that individual variation in the host-microbial mutualism is
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Maev, I. V., A. I. Levchenko, and D. N. Andreev. "Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data." Russian Journal of Gastroenterology, Hepatology, Coloproctology 32, no. 4 (2022): 17–26. http://dx.doi.org/10.22416/1382-4376-2022-32-4-17-26.

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The purpose of the review. To systematize literature data on changes in the structure of the intestinal microbiota in patients with chronic pancreatitis (CP).Key findings. The human intestinal microbiota is a dynamically changing system that is constantly undergoing qualitative and quantitative changes, especially in several pathological conditions of the digestive system. At present, the differences in the intestinal microbiota in pancreatic diseases are poorly understood. The severe CP is associated with impaired synthesis of antimicrobial peptides, bicarbonates, and digestive enzymes by the
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Sitkin, S. I., and T. M. Pervunina. "Chronic pancreatitis and the intestinal microbiome in adults and children: Not only SIBO but also gut dysbiosis has clinical significance." Experimental and Clinical Gastroenterology, no. 12 (January 16, 2022): 125–33. http://dx.doi.org/10.31146/1682-8658-ecg-196-12-125-133.

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Chronic pancreatitis is accompanied by both small intestinal bacterial overgrowth and dysbiosis of the gut microbiota. The most typical changes in the gut microbiota in chronic pancreatitis are a decrease in microbial diversity, an increase in the abundance of Proteobacteria, a decrease in the abundance of Bacteroidetes, Actinobacteria, and Firmicutes, especially butyrate-producing bacteria such as Faecalibacterium, a significant association with infectious pathways (KEGG analysis]), concomitant metabolic disorders (diabetes mellitus) and exocrine pancreatic insufficiency. Changes in the gut m
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Dissertations / Theses on the topic "Dysbiotic changes"

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Kalutskyi, I. V. "Level of dysbiotic changes in patients with chronic purulent superchain sinusitis." Thesis, БДМУ, 2022. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19800.

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Book chapters on the topic "Dysbiotic changes"

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Ragbetli, Murat Cetin, and Seda Keskin. "A Current Review on Diabetes Mellitus Induced Gut Microbiota and Histological Changes." In Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism. Nobel Tip Kitabevleri, 2023. http://dx.doi.org/10.69860/nobel.9786053359104.2.

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Recent studies have highlighted the intricate relationship between diabetes mellitus (DM) and alterations in gut microbiota composition, as well as associated histological changes. Dysbiosis, characterized by an imbalance in microbial communities, has been observed in diabetic individuals, with decreased microbial diversity and altered abundance of specific taxa such as Firmicutes and Bacteroidetes. These changes are implicated in promoting systemic inflammation, insulin resistance, and metabolic dysfunction. Concurrently, diabetic conditions influence gut barrier integrity and mucosal immunit
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E. Khrulev, Alexey, Irina V. Belova, Irina V. Soloveva, et al. "Specific Cerebrovascular Risk Factors, Colon Microbiocenosis and Its Correction in Patients Receiving Long-Term Programmed Hemodialysis." In Multidisciplinary Experiences in Renal Replacement Therapy. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101300.

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Introduction: The problem of acute and chronic cerebrovascular disorders in dialysis patients remains the most urgent. Risk factors for cerebrovascular diseases in CKD and dialysis patients can be conditionally divided into “traditional” (arterial hypertension, diabetes mellitus, hypercholesterolemia) and “specific” (associated with renal pathology and dialysis procedures). The spectrum of specific factors of cerebrovascular risk in patients with dialysis stage of the CKD includes specific dialysis factors that form during programmed HD, as well as impaired phosphorus-calcium metabolism and ca
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González-González, Alicia, Aurora Laborda-Illanes, Soukaina Boutriq, et al. "A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis." In Melatonin - Recent Updates [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106068.

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In this chapter, we describe the possible link between gut microbiota, melatonin, and breast cancer disease. It is widely described that changes in melatonin production due to circadian disruption is one of the causes of breast cancer. In addition, recently it is described that dysbiosis caused by changes in the gut microbiota composition could be as well constitute an important factor to induce breast cancer. The dysbiosis process, in turn, induces the stimulation of kynurenine pathway, leading to reduced circulating melatonin levels. Therefore, in this chapter we deep into the relationship b
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Starishko, Oksana, and Olha Voronkova. "LACTOBACYLLI IN THE MICROBIOTA OF THE REPRODUCTIVE TRACT OF WOMEN WHO SMOKE AND DO NOT SMOKE." In Modernization of research area: national prospects and European practices. Publishing House “Baltija Publishing”, 2022. http://dx.doi.org/10.30525/978-9934-26-221-0-16.

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In recent years, there has been an increase in the number of cases of dysbiotic disorders of the urogenital tract of women. Changes in the environment, smoking, malnutrition, acute intestinal infections, chronic diseases and dysfunction of the gastrointestinal tract, widespread use of antibiotics, decreased immunological reactivity of the body, long-term use of oral contraceptives, hormonal disorders, menstrual disorders – may be accompanied by menstrual disorders be the causes of imbalance of the resident microbiota and the occurrence of vaginal dysbacteriosis. This poses a significant risk o
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Silva, Ana Rita, Maria Alexandra Bernardo, Maria Fernanda Mesquita, et al. "Dysbiosis, Small Intestinal Bacterial Overgrowth, and Chronic Diseases." In Treating Endocrine and Metabolic Disorders With Herbal Medicines. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-4808-0.ch015.

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Dysbiosis is characterized by an alteration in quantity and quality of intestinal microbiota composition. In the presence of dysbiosis, enterocytes will have difficulty in maintaining the integrity of the mucosal barrier, leading to increased intestinal permeability. These events are recognised to be linked to several chronic diseases. One of the consequences of dysbiosis is the manifestation of small intestinal bacterial overgrowth (SIBO), which is associated to a variety of chronic diseases. Single food nutrients and bioactive molecules, food additives, pre- and probiotics, and different die
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Roy, Tapas Kumar, Arnab Roy, Swati Bairagya, and Sanjay Dey. "The Role of Gut Microbiota in Ocular Diseases." In Gut Microbiota and their Impact on Disease Pathways and Interventions. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815324549125010009.

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The adaptive environment that is crucial to the host’s health is the microbiome. Several research works have revealed that dysbiosis, or changes in the gut microbiota of humans can have an involvement in the etiology of a number of prevalent ailments, including diabetes, cancer, and neuropsychiatric disorders. Nonetheless, recent findings indicate the potential for a gut-eye axis, in which gut dysbiosis suggests a crucial role in the progression and development of an array of ocular conditions, that include uveitis, diabetic retinopathy, glaucoma and age-related macular degeneration. Current t
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Foroudi Pourdeh, Elham, and Izzet Ulker. "Do all Bariatric Surgery Methods Have the Same Effects on the Gut Microbiota?" In Bariatric Surgery - Past and Present [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.107176.

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Despite the various treatment methods that exist for obesity, the most effective treatment for long-term weight control is bariatric surgery. Different surgical methods affect different mechanisms, such as appetite change, restriction of intake, and control of hunger. Divert food from the proximal part of the small intestine, food aversion, increased energy expenditure, malabsorption of macronutrients, and modifications of bile aside profiles and the gut microbiota. Gut microbiota plays an important role in maintaining human health. Dysbiosis usually has detrimental effects and may also have l
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Gradisteanu Pircalabioru, Gratiela, Octavian Savu, Grigore Mihaescu, Ovidiu Vrancianu, and Mariana-Carmen Chifiriuc. "Dysbiosis, Tolerance, and Development of Autoimmune Diseases." In Immunology of the GI Tract [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104221.

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The pathogenesis of autoimmune diseases (AIDS) is not only attributed to genetic susceptibility, but also to environmental factors, among which, those disturbing gut microbiota have attracted increasing attention lately. Healthy gut microbiota has beneficial effects on the development and activity of the immune system, playing a central role in peripheric tolerance. Compositional and functional changes in gut microbiota were reported in various AIDS, and increasing evidence suggests that disturbed gut microbiota contributes to their immunopathogenesis. Thyroid and intestinal diseases prevalent
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Gómez-Escudero, Octavio. "Drug-Related Enteropathy." In Diarrhea - Novel Advances and Future Perspectives in the Etiological Diagnosis and Management [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.103734.

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Over 700 drugs have been implicated as cause of chronic diarrhea and potential enteral damage. Pathophysiologic mechanisms include intrinsic malabsorption as their main mode of action (i.e., acarbose or orlistat), increased risk of microscopic colitis/enteritis (proton-pump inhibitors (PPI), non-steroidal anti-inflammatory drugs (NSAID), selective serotonin reuptake inhibitors (SSRI)), dysbiosis (antibiotics, metformin, PPI), and microscopic or overt enteropathy (angiotensin inhibitors, antineoplastic agents, targeted therapy and check-point inhibitors). According to type, diarrhea can be mala
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Auguet, Teresa, Laia Bertran, and Jessica Binetti. "Intestinal Dysbiosis and Non-Alcoholic Fatty Liver Disease." In Human Microbiome. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.92972.

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Non-alcoholic fatty liver disease (NAFLD) affects 20–30% of the population, with an increased prevalence in industrialized regions. Some patients with NAFLD develop an inflammatory condition termed non-alcoholic steatohepatitis (NASH) that is characterized by hepatocellular injury, innate immune cell-mediated inflammation, and progressive liver fibrosis. In clinical practice, abdominal imaging, which reveals hepatic steatosis, is sufficient for NAFLD diagnosis if other diseases have been rejected. However, a liver biopsy is needed to differentiate NASH from simple steatosis. Therapeutic strate
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Conference papers on the topic "Dysbiotic changes"

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Sinitsa, A. V., I. A. Velicjan, and M. Y. Soom. "METABIOTICS AND PREBIOTICS IN THE TREATMENT OF POST-COVID SYNDROME." In Practice Oriented Science: UAE – RUSSIA – INDIA. Crossref, 2024. http://dx.doi.org/10.34660/inf.2024.39.10.166.

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Almost half of patients with COVID-19 also experience GI symptoms. The long-term consequences of COVID-19 (long-COVID syndrome) include asthenia and GI problems: diarrhea, constipation, acid reflux, and abdominal pain. New microbial-derived substances with increased safety profile – metabiotics/postbiotics - are promising in correction of GI symptoms. A new supplement containing metabiotic from Bacillus subtilis and FOS (Bactimunal®, Kraft Group Ltd, Russian Federation) is effective in patients with long-COVID syndrome reducing asthenia, GI complaints, and dysbiotic changes in GI microbiome. O
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Ozdemir, T., A. Fedorec, and C. Barnes. "Toxin-Antitoxin Stabilised Biosensors in the Commensal Escherichia coli Nissle 1917 for the Detection of Dysbiotic Changes in the Intestinal Microbiota." In IET/SynbiCITE Engineering Biology Conference. Institution of Engineering and Technology, 2016. http://dx.doi.org/10.1049/cp.2016.1242.

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Kurbonnazarova, Maftuna, Arthi Rameshkumar, Olivia R. Siciliano, Samrat Gollapudi, Katarina Rusinak, and Alissa Brotman O'Neill. "Gut Microbiota Changes After Cholecystectomy: Unraveling the Microbial Mysteries - A Systematic Review." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.97_2024.

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Aims: This review aims to expand upon previous research examining change in gastrointestinal microbiota before and after cholecystectomy. Methods: A systematic review, combined with a pooled analysis, was conducted to assess gut microbiota dysbiosis post-cholecystectomy, utilizing 71 articles retrieved from 3 databases, with 13 undergoing full-text appraisal. The publication dates ranged from 2018 to 2023. Results: Results suggested a greater degree of microbiota alteration in symptomatic post-cholecystectomy patients, characterized by a decrease in the Firmicutes/Bacteroidetes ratio, Bifidoba
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Nogueira, Fábio Dias, Ana Klara Rodrigues Alves, Barbara Beatriz Lira da Silva, et al. "The autistic spectrum disorder and its relation to intestinal dysbiosis." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.283.

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Introduction: Autistic Spectrum Disorder (ASD) is characterized by a neurodevelopmental disorder, in which the child has persistent deficits in verbal and / or non-verbal communication, social interaction and behavior. One of the factors related to the cause of ASD are nutritional aspects, such as intestinal dysbiosis. Objective: To analyze the relationship between imbalance in the intestinal microbiota and the pathophysiological characteristics of ASD. Methodology: This is a systematic review, carried out in the Pubmed, SciELO databases, in order to answer the question: what is the relationsh
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Pereira, Clarice de Abreu, Amanda Souza Bandeira, Gabriel Luis Pozzan, Luis Guilherme Fernandes Costa Lima, and Adeni Ferreira dos Santos Junior. "Bacteriophages in the treatment of Inflammatory Bowel Disease." In III Seven International Medical and Nursing Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/iiicongressmedicalnursing-030.

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Introduction: Inflammatory bowel diseases are the result of an interaction between environmental, genetic and immunological factors, which result in a persistent inflammatory process in the intestines. The relationship between the intestinal microbiota and its influence and possible changes in IBD is not completely clear, however it is believed that the existence of a local inflammatory process generates changes, i.e. intestinal dysbiosis, often associated with the development of symptoms. The treatment of IBD depends on the signs and symptoms presented by the patient and may include aminosali
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Reports on the topic "Dysbiotic changes"

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Barros-Poblete, Marisol, Rodrigo Torres-Castro, Mauricio Henríquez, Anita Guequen, Isabel Blanco, and Carlos Flores. Dysbiosis as a prognostic factor for clinical worsening in chronic respiratory disease: A systematic review and metanalysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0089.

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Review question / Objective: Is dysbiosis a prognostic factor for clinical worsening in patients with chronic respiratory diseases?. Condition being studied: Dysbiosis, defined as changes in the quantitative and qualitative composition of the microbiota. Eligibility criteria: Over 18 years old adult patients with chronic respiratory diseases clinical diagnosis (cystic fibrosis, chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, interstitial lung disease, sarcoidosis, bronchiectasis, non-CF bronchiectasis, pulmonary hypertension) according to the International Statist
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