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1

Carlos, Kaski Juan, and Holt David W, eds. Myocardial damage: Early detection by novel biochemical markers. Kluwer Academic, 1998.

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2

Policy, Toronto Working Group on Cholesterol. Detection and management of asymptomatic hypercholesterolemia: A policy document. s.n., 1989.

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3

Shen, Ze-ping. An application of neural networks for the detection of coronary heart disease. Brunel University, 1994.

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4

McCarthy, Joseph C. Early hip disorders: Advances in detection and minimally invasive treatment. Springer, 2011.

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5

name, No. Early hip disorders: Advances in detection and minimally invasive treatment. Springer, 2003.

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6

editor, Mordini E. (Emilio), and Green Manfred editor, eds. Internet-based intelligence in public health emergencies: Early detection and response in disease outbreak crises. IOS Press, 2011.

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7

Rosen, Shara. Trends in the early diagnosis of cardiovascular disease: Worldwide market opportunities. Kalorama Information, 2001.

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8

Fitzgerald, Rebecca C. Pre-invasive disease: Pathogenesis and clinical management. Springer, 2011.

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9

Patlak, Margie. Mammography and beyond: Developing technologies for the early detection of breast cancer : a non-technical summary. Edited by National Cancer Policy Board (U.S.). Committee on the Early Detection of Breast Cancer and National Research Council (U.S.). Commission on Life Sciences. National Academy Press, 2001.

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10

Wells, F. O. Preventive medicine: Working for patients : a review of the therapeutic areas where screening programmes and the early detection and treatment of disease will benefit patients and the NHS. Association of the British Pharmaceutical Industry, 1989.

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11

S, Luxenberg Jay, and Better Health Foundation, eds. You can't live forever, you can live 10 years longer with better health: A practical guide to reducing your risk of dying early from heart disease, cancer, stroke, osteoporosis & accidents. Better Health Foundation & UCSF/Mount Zion, 1993.

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12

(Editor), J. C. Kaski, and David W. Holt (Editor), eds. Myocardial Damage: Early Detection by Novel Biochemical Markers. Springer, 1998.

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13

Holt, David W., and Juan Carlos Kaski. Myocardial Damage: Early Detection by Novel Biochemical Markers. Springer London, Limited, 2013.

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14

Myocardial Damage: Early Detection by Novel Biochemical Markers. Springer Netherlands, 2010.

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15

Tribouilloy, Christophe, Patrizio Lancellotti, Ferande Peters, José Juan Gómez de Diego, and Luc A. Pierard. Heart valve disease (aortic valve disease): aortic regurgitation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0033.

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Echocardiography is the cornerstone examination for the assessment of aortic regurgitation (AR): it provides reliable evaluation of the aortic valve and allows diagnosis and identification of the mechanism of regurgitation. The specific aetiology of the disease can be identified in the majority of cases. A combination of quantitative and quantitative Doppler and two-dimensional (2D) echocardiographic parameters allows the evaluation of the severity of AR and determination of the haemodynamic and left ventricular function repercussions. Echocardiography allows the detection of associated lesion
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16

Morrison, Karen. Prevention of cerebrovascular disease. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0348.

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Stroke is the main cause of neurological morbidity in adults and the third most common cause of death worldwide after ischaemic heart disease and cancer (all forms combined). It is more common in older people, with three-quarters of strokes occurring in people over 65 years of age, and estimates are that overall stroke morbidity will double by the early 2020s. The worldwide figure of increasing incidence of stroke detection masks the fact that mortality from stroke has actually been falling in developed countries since the latter half of the twentieth century while the mortality has continued
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17

Hoyle, Nicholas R., Thompson Michael, Richard Morgan, Subrayal M. Reddy, and Damien Arrigan. Early Detection of Biomarkers for Disease. Royal Society of Chemistry, The, 2017.

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18

Hagendorff, Andreas. Cardiac involvement in systemic diseases. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199599639.003.0020.

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Systemic diseases are generally an interdisciplinary challenge in clinical practice. Systemic diseases are able to induce tissue damage in different organs with ongoing duration of the illness. The heart and the circulation are important targets in systemic diseases. The cardiac involvement in systemic diseases normally introduces a chronic process of alterations in cardiac tissue, which causes cardiac failure in the end stage of the diseases or causes dangerous and life-threatening problems by induced acute cardiac events, such as myocardial infarction due to coronary thrombosis. Thus, diagno
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19

Seipel, L., and Franz Loogen. Detection of Ischemic Myocardium with Exercise. Springer London, Limited, 2011.

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20

Seipel, L., and Franz Loogen. Detection of Ischemic Myocardium with Exercise. Springer London, Limited, 2012.

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21

Early Detection of Alzheimer's Disease: A Neuropsychological Approach. Academic & Scientific Publishers, 2008.

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22

Gao, Youhe. Urine: Promising Biomarker Source for Early Disease Detection. Springer, 2019.

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23

Albert, Marilyn S., and Guy M. Mckhann. Neuroethical Issues In Early Detection Of Alzheimer’S Disease. Oxford University Press, 2011. http://dx.doi.org/10.1093/oxfordhb/9780199570706.013.0135.

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24

Gao, Youhe. Urine: Promising Biomarker Source for Early Disease Detection. Springer Singapore Pte. Limited, 2020.

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25

Chan, Dennis. Early Detection in Alzheimer's Disease: Biological and Technological Advances. Academic Press, 2021.

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26

Chan, Dennis. Early Detection in Alzheimer's Disease: Biological and Technological Advances. Elsevier Science & Technology Books, 2021.

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27

Tragante, Vinicius, Anna Pilbrow, and Katrina Poppe, eds. Improving Early Detection and Risk Prediction in Heart Failure. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-322-1.

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28

Edoh, Thierry. Pre-Screening Systems for Early Disease Prediction, Detection, and Prevention. IGI Global, 2018.

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29

C, Morris John, and Jeffrey M. Burns. Mild Cognitive Impairment and Early Alzheimer's Disease: Detection and Diagnosis. Wiley & Sons, Incorporated, John, 2008.

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30

Peacock, Linzi, and Rachel Hignett. Acquired heart disease. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0041.

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Heart disease in pregnancy is a leading cause of maternal death worldwide. In the United Kingdom and United States, heart disease in pregnancy is the commonest cause of maternal death. In Europe, over 1% of maternal deaths are attributable to structural heart disease. In addition, heart disease in pregnancy is a significant cause of severe maternal and fetal morbidity. Whilst the vast majority of women with heart disease in pregnancy have underlying congenital heart disease, most maternal deaths are due to acquired heart disease (AHD). As the risk factors for AHD become ever more prevalent, th
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31

Pericardial Mesothelioma. Exon Publications, 2024. https://doi.org/10.36255/pericardial-mesothelioma.

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Pericardial Mesothelioma is a rare and aggressive cancer that develops in the lining of the heart, known as the pericardium. This article provides a comprehensive guide to understanding this challenging condition, offering clear and practical information for patients, caregivers, and the general public. It begins by explaining what pericardial mesothelioma is, its causes, and the primary role of asbestos exposure in its development. The article explores the different types of pericardial mesothelioma and discusses risk factors, symptoms, and the pathophysiology of the disease. Key sections cov
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32

Bass, Cristina, Barbara Bauce, and Gaetano Thiene. Arrhythmogenic right ventricular cardiomyopathy: diagnosis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0360.

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Arrhythmogenic cardiomyopathy is a heart muscle disease clinically characterized by life-threatening ventricular arrhythmias and pathologically by an acquired and progressive dystrophy of the ventricular myocardium with fibrofatty replacement. The clinical manifestations of arrhythmogenic cardiomyopathy vary according to the ‘phenotypic’ stage of the underlying disease process. Since there is no ‘gold standard’ to reach the diagnosis of arrhythmogenic cardiomyopathy, multiple categories of diagnostic information have been combined. Different diagnostic categories include right ventricular morp
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33

High Cholesterol: Education for Patients and the Public. Exon Publications, 2025. https://doi.org/10.36255/high-cholesterol.

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High cholesterol is a common health condition that increases the risk of heart disease, stroke, and other cardiovascular problems. This article provides a comprehensive guide on high cholesterol, including its causes, symptoms, diagnosis, treatment, and long-term management. It begins with an explanation of what cholesterol is and how excessive levels can harm the body. The article highlights the widespread prevalence of high cholesterol, noting how lifestyle choices and genetic factors, including mutations in the LDLR, APOB, and PCSK9 genes, play a role in cholesterol regulation. The symptoms
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34

Lemiere, Jurgen. Huntington's Disease: Early Detection & Progression of Cognitive Changes in Patients & Asymptomatic Mutation Carriers (Acta Biomedica Lovaniensia). Leuven Univ Pr, 2004.

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35

Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Cholesterol Education Program, 1989.

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36

Karatasakis, G., and G. D. Athanassopoulos. Cardiomyopathies. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199599639.003.0019.

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Echocardiography is a key diagnostic method in the management of patients with cardiomyopathies.The main echocardiographic findings of hypertrophic cardiomyopathy are asymmetric hypertrophy of the septum, increased echogenicity of the myocardium, systolic anterior motion, turbulent left ventricular (LV) outflow tract blood flow, intracavitary gradient of dynamic nature, mid-systolic closure of the aortic valve and mitral regurgitation. The degree of hypertrophy and the magnitude of the obstruction have prognostic meaning. Echocardiography plays a fundamental role not only in diagnostic process
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37

Rose, Kelly. Heart Illness Explained: Heart or Cardiovascular Disease, Its Symptoms and Early Warning Signals, and How to Avoid Them. Independently Published, 2022.

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38

Fye, W. Bruce. President Roosevelt’s Secret Hypertensive Heart Disease. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199982356.003.0007.

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Franklin D. Roosevelt’s health was a factor in the 1944 election. Presidential press secretary Stephen Early and White House physician Ross McIntire worried that Thomas Dewey might win if voters learned that Roosevelt had severe hypertension and had an episode of congestive heart failure. Three weeks before the election, Mayo cardiologist Arlie Barnes visited the Bethesda Naval Medical Center where he learned that some physicians suspected that Roosevelt had a “serious heart ailment.” When Barnes returned to Rochester he mentioned this to a few friends. Word of this conversation reached Early,
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39

Dob, Daryl P., Elspeth E. Pickering, and Michael A. Gatzoulis. Moderate to complex congenital heart disease. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0040.

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Children born with congenital heart disease no longer face the prospect of early death and a poor quality of life. In fact, most neonates with moderate to complex congenital heart disease have a survival rate to adulthood of over 80%. The ratio of adults to children with congenital heart disease is increasing, due to better surgical repairs, and longer survival with a better quality of life. In the Western world, there are more adults than children alive with congenital heart disease. This remarkable medical effort has allowed young women with congenital heart disease to mature to an age where
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40

Fitzgerald, Rebecca C. Pre-Invasive Disease: Pathogenesis and Clinical Management. Springer, 2014.

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41

(Publisher), Boardroom Inc. Bottom Line's Red Flags: Symptoms and Early Warning Signs of Heart Disease, Cancer, Diabetes...and More. Boardroom Inc., 2007.

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42

Martinez, Jaun Jair. An international telemedicine model design: Using e-health to improve chronic disease early detection and initial management in rural areas. 2005.

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43

Aluisy, Roman, and Bill Blanchet. Caught Early: How Baseline Imaging Can Detect Early Heart Disease and Cancer, and How to Prevent Them in the First Place. Rogue Publishing Partners, 2024.

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44

Aluisy, Roman, and Bill Blanchet. Caught Early: How Baseline Imaging Can Detect Early Heart Disease and Cancer, and How to Prevent Them in the First Place. Rogue Publishing Partners, 2024.

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45

Aluisy, Roman, and Bill Blanchet. Caught Early: How Baseline Imaging Can Detect Early Heart Disease and Cancer, and How to Prevent Them in the First Place. Rogue Publishing Partners, 2024.

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46

Wise, Matt, and Paul Frost. Critical illness. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0147.

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Critical illness can be considered to be any disease process which causes physiological instability that leads to disability or death within minutes or hours. Fortunately, physiological instability associated with critical illness is easily detected by perturbations of simple clinical observations such as blood pressure, heart rate, respiratory rate, oxygen saturations, level of consciousness, and urine output. Individual abnormalities in these observations are sensitive for the presence of critical illness but non-specific. Specificity for critical illness improves as the number of abnormal c
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47

Pasquet, Agnes, Marcia Barbosa, and Jo-Nan Liao. Systemic disease and other conditions: the heart during pregnancy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0056.

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Normal pregnancy represents a haemodynamic challenge for the heart. The main changes are increases in blood (plasma) volume and cardiac output, and a decrease in systemic vascular resistance. These change start early during pregnancy and will be maximal around the 24th week of gestation. This translates into echocardiographic changes such as increase in ventricular volume, stroke volume, and changes in geometry. Peripartum cardiomyopathy is a left ventricular dysfunction without any underlying cause, arising near the end of the gestation or in the early postpartum period. Echocardiography is t
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48

Kelly, Laura, and William P. Stanford. Implementation of Personalized Precision Medicine: Expanding the Clinical Vision Towards Prevention, Early Detection and Precision Treatment of Disease to Drive Extended Healthspan. Elsevier Science & Technology, 2023.

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49

Kelly, Laura, and William P. Stanford. Implementation of Personalized Precision Medicine: Expanding the Clinical Vision Towards Prevention, Early Detection and Precision Treatment of Disease to Drive Extended Healthspan. Elsevier Science & Technology Books, 2023.

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50

Options, Easy Health. Nature's Simple Solutions for Avoiding Heart Disease - and How NOT to Become a Statistic: Your Step-by-tep Guide to Prevention, Detection, and Natural Treatment Strategies. Easy Health Options, 2008.

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