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Relevant bibliographies by topics / Effectiveness simvastatin

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Academic literature on the topic 'Effectiveness simvastatin'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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Journal articles on the topic "Effectiveness simvastatin"

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Hjalte, Krister, Björn Lindgren, and Ulf Persson. "Cost-Effectiveness of Simvastatin Versus Cholestyramine." PharmacoEconomics 1, no. 3 (1992): 213–16. http://dx.doi.org/10.2165/00019053-199201030-00009.

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Wong, George Kwok Chu, Min Liang, Haibin Tan, et al. "High-Dose Simvastatin for Aneurysmal Subarachnoid Hemorrhage." Neurosurgery 72, no. 5 (2013): 840–44. http://dx.doi.org/10.1227/neu.0b013e31828ab413.

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Abstract BACKGROUND: Experimental evidence has indicated the benefit of simvastatin in the treatment of subarachnoid hemorrhage. However, no clinical data are available to answer whether a high-dose regimen is more effective than a normal-dose regimen, even though the biochemical actions and related neuroprotective mechanisms are thought to be dose related. OBJECTIVE: To determine whether 80 mg simvastatin daily (high dose) over 3 weeks initiated within 96 hours of the ictus will reduce the incidence of delayed ischemic deficits after subarachnoid hemorrhage compared with 40 mg simvastatin dai

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Jisha, U.*1 Prasanth S. S.2 Sibina M. K.3 Sanooja P.K.4 K. T. Akshara5 Riya Rajan6 Mohammed Farooq7 Ajay A.8. "A Review On Mastering Bioanalytical Sample Preparation Techniques: Achieving Accurate Analysis." International Journal in Pharmaceutical Sciences 2, no. 8 (2024): 3806–21. https://doi.org/10.5281/zenodo.13371808.

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The Self-Double Emulsifying Drug Delivery System (SDEDDS) was a type of system where particles of one substance were dispersed within another. Simvastatin, a drug that lowered cholesterol, had a short half-life and only 5% bioavailability due to first-pass metabolism, making it a good candidate for SDEDDS. This study focused on improving Simvastatin's solubility and dissolution rate and various formulations of Simvastatin were prepared using SDEDDS, and all demonstrated quick emulsification times, high cloud points, and acceptable viscosity levels. The efficiency with which the drug was entrap

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4

Ariani, Ariani, Putrya Hawa, and Syaefudin Ali Akhmad. "Comparison between Effectiveness of Pomegranate Juice (Punica granatum) and Simvastatin for Lowering Blood LDL Level in Hypercholesterolemic Male Rats (Rattus novergicus)." Bangladesh Journal of Medical Science 15, no. 2 (2016): 216–19. http://dx.doi.org/10.3329/bjms.v15i2.28791.

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Background: Coronary heart disease (CHD) is one of the leading causes of death in developed and developing countries. In Indonesia 26% of death is caused by CHD. Hypercholesterolemia is one of the risk factors for CHD. Simvastatin is a hypolipidemic drug which has a significant number of side effects such as myopathy. While, Pomegranate juice (Punica granatum) contains anthocyanin, cathechins, tanin, vitamin C and vitamine E which have beneficial effects to decrease blood LDL level. Objective: The aim of this study was to compare the effectiveness of pomegranate juice (Punica granatum) and sim

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&NA;. "Simvastatin improves cost effectiveness of costly interventions." Inpharma Weekly &NA;, no. 1183 (1999): 5. http://dx.doi.org/10.2165/00128413-199911830-00010.

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Di Veroli, C., and R. Pastorelli. "Effectiveness and tolerability of simvastatin versus pravastatin." Current Therapeutic Research 52, no. 1 (1992): 1–6. http://dx.doi.org/10.1016/s0011-393x(05)80429-1.

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Rayasilp, Kritsakorn, Piyanuch Wonganan, Pajaree Chariyavilaskul, Nuntaporn Prompila, Varumporn Sukkummee, and Supeecha Wittayalertpanya. "Effect of Pomelo Juice on the Pharmacokinetics of Simvastatin, CYP3A2 Activity and Mdr1a, Mdr1b and Slc21a5 Expressions in Rats." Pharmaceutical Sciences 25, no. 4 (2019): 303–10. http://dx.doi.org/10.15171/ps.2019.45.

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Background: Food-drug interaction can decrease drug effectiveness or increase risk of drug toxicity. Simvastatin is widely used for treatment of hypercholesterolemia and hypertriglyceridemia. Therefore, this study aimed to investigate the effects of pomelo juice on the pharmacokinetics of simvastatin, CYP3a2 activity and Mdr1a, Mdr1b and Slc21a5 expressions in rats. Methods: Rats were divided into 4 groups including (i) control, (ii) pomelo that received pomelo juice orally twice daily for 7 days, (iii) simvastatin that received simvastatin on day 8, and (iv) simvastatin + pomelo juice. Plasma

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Aboutaleb, Nahid, Mahdieh Mehrab Mohseni, and Maryam Naseroleslami. "Cardioprotective effects of simvastatin‑loaded nano‑niosomes on cardiomyocytes in cardiac ischemia." Medical Journal of Tabriz University of Medical Sciences 45, no. 3 (2023): 111–23. http://dx.doi.org/10.34172/mj.2023.026.

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Background. Cardiac ischemia is the major cause of morbidity and mortality which can be increased by Statins. This study aimed to increase the effectiveness of simvastatin in the form of niosomes. Methods. In this study, 25 male Wistar rats were divided into 5 groups: control, ischemia (induced by closed LAD), ischemia receiving nano-niosomes, ischemia receiving simvastatin, and ischemia receiving simvastatin-loaded nano-niosomes. One month after the drug injection, RNA was extracted from the heart tissue of the studied groups, cDNA was synthesized, and a real-time PCR test was performed using

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9

Neetika Gupta, Sherry Verma, Siddharth Sharma, et al. "Effectiveness Of 1.2% Simvastatin Gel as an Adjunct to Non-Surgical Therapy in The Treatment of Chronic Periodontitis: A Split Mouth Randomized Controlled Trial." International Healthcare Research Journal 4, no. 12 (2021): OR1—OR6. http://dx.doi.org/10.26440/ihrj/0412.03396.

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BACKGROUND: Periodontitis is an inflammatory disease that results in bone resorption creating bony defects, which may cause tooth loss. AIM: The present study aimed to evaluate the effectiveness of 1.2% Simvastatin gel as an adjunct to non-surgical therapy to treat chronic periodontitis (CP). MATERIALS AND METHOD: 25 patients with 50 sites were categorized into two treatment groups: Scaling and Root Planing plus 1.2% Simvastatin, and Scaling and Root Planing with placebo. Clinical parameters; site-specific plaque index, modified sulcus bleeding index (mSBI), pocket probing depth (PD), and rela

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Lu, Jinya, Hongli Cai, Yefei Li, and Jiayi Chen. "Effectiveness of simvastatin/aspirin combination in the treatment of coronary heart disease in the elderly, and its effect on cardiac function and levels of inflammatory factors." Tropical Journal of Pharmaceutical Research 21, no. 5 (2022): 1095–100. http://dx.doi.org/10.4314/tjpr.v21i5.26.

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Purpose: To investigate the efficacy of simvastatin plus aspirin in the treatment of coronary heart disease in the elderly, and its effect on cardiac function and inflammatory factor levels.Methods: Eighty-seven identified elderly patients with coronary heart disease who were admitted to Nantong First People's Hospital, Nantong, China between January 2020 and June 2021 were recruited and assigned at a ratio of 1:1 to receive either conventional treatment (group A) or simvastatin plus aspirin (group B). The clinical endpoint was treatment efficacy.Results: No significant differences were found

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Dissertations / Theses on the topic "Effectiveness simvastatin"

1

Приступа, Людмила Никодимівна, Людмила Никодимовна Приступа, Liudmyla Nykodymivna Prystupa та Т. І. Циганкова. "Клініко-імунологічна ефективність симвастатину у хворих із тяжким перебігом хронічного обструктивного захворювання легень". Thesis, Видавництво СумДУ, 2010. http://essuir.sumdu.edu.ua/handle/123456789/4834.

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