Relevant bibliographies by topics / Encapsulated peptide

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Encapsulated peptide'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Encapsulated peptide"

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Drury, Jeanie L., Tanyarut Boontheekul, and David J. Mooney. "Cellular Cross-linking of Peptide Modified Hydrogels." Journal of Biomechanical Engineering 127, no. 2 (2004): 220–28. http://dx.doi.org/10.1115/1.1865194.

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Peptide modification of hydrogel-forming materials is being widely explored as a means to regulate the phenotype of cells immobilized within the gels. Alternatively, we hypothesized that the adhesive interactions between cells and peptides coupled to the gel-forming materials would also enhance the overall mechanical properties of the gels. To test this hypothesis, alginate polymers were modified with RGDSP-containing peptides and the resultant polymer was used to encapsulate C2C12 myoblasts. The mechanical properties of these gels were then assessed as a function of both peptide and cell dens
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Cresti, Laura, Gemma Conte, Giovanni Cappello, et al. "Inhalable Polymeric Nanoparticles for Pulmonary Delivery of Antimicrobial Peptide SET-M33: Antibacterial Activity and Toxicity In Vitro and In Vivo." Pharmaceutics 15, no. 1 (2022): 3. http://dx.doi.org/10.3390/pharmaceutics15010003.

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Development of inhalable formulations for delivering peptides to the conductive airways and shielding their interactions with airway barriers, thus enhancing peptide/bacteria interactions, is an important part of peptide-based drug development for lung applications. Here, we report the construction of a biocompatible nanosystem where the antimicrobial peptide SET-M33 is encapsulated within polymeric nanoparticles of poly(lactide-co-glycolide) (PLGA) conjugated with polyethylene glycol (PEG). This system was conceived for better delivery of the peptide to the lungs by aerosol. The encapsulated
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Santos, Daniel Moreira dos, Livia Ramos Santiago, Nayara Araújo dos Santos, et al. "Encapsulated LyeTx III Peptide: Cytotoxic Agent Isolated from Lycosa erythrognatha Spider Venom." Toxins 17, no. 1 (2025): 32. https://doi.org/10.3390/toxins17010032.

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The discovery of novel cytotoxic drugs is of paramount importance in contemporary medical research, particularly in the search for treatments with fewer side effects and higher specificity. Antimicrobial peptides are an interesting class of molecules for this endeavor. In this context, the LyeTx III, a new peptide extracted from the venom of the Lycosa erythrognatha spider, stands out. The peptide exhibits typical antimicrobial traits: a positive net charge and amphipathic α -helix structure in lipid-like environments. Its unique sequence (GKAMKAIAKFLGR-NH2), identified via mass spectrometry a
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Nakamura, Yoko, Yuki Sato, Hiroshi Inaba, Takashi Iwasaki та Kazunori Matsuura. "Encapsulation of mRNA into Artificial Viral Capsids via Hybridization of a β-Annulus-dT20 Conjugate and the Poly(A) Tail of mRNA". Applied Sciences 10, № 22 (2020): 8004. http://dx.doi.org/10.3390/app10228004.

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Messenger RNA (mRNA) drugs have attracted considerable attention as promising tools with many therapeutic applications. The efficient delivery of mRNA drugs using non-viral materials is currently being explored. We demonstrate a novel concept where mCherry mRNA bearing a poly(A) tail is encapsulated into capsids co-assembled from viral β-annulus peptides bearing a 20-mer oligothymine (dT20) at the N-terminus and unmodified peptides via hybridization of dT20 and poly(A). Dynamic light scattering measurements and transmission electron microscopy images of the mRNA-encapsulated capsids show the f
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Sone, Eli D., and Samuel I. Stupp. "Semiconductor-Encapsulated Peptide−Amphiphile Nanofibers." Journal of the American Chemical Society 126, no. 40 (2004): 12756–57. http://dx.doi.org/10.1021/ja0499344.

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Sodhi, Harkanwalpreet, and Alyssa Panitch. "A Tunable Glycosaminoglycan–Peptide Nanoparticle Platform for the Protection of Therapeutic Peptides." Pharmaceutics 16, no. 2 (2024): 173. http://dx.doi.org/10.3390/pharmaceutics16020173.

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The popularity of Glycosaminoglycans (GAGs) in drug delivery systems has grown as their innate ability to sequester and release charged molecules makes them adept in the controlled release of therapeutics. However, peptide therapeutics have been relegated to synthetic, polymeric systems, despite their high specificity and efficacy as therapeutics because they are rapidly degraded in vivo when not encapsulated. We present a GAG-based nanoparticle system for the easy encapsulation of cationic peptides, which offers control over particle diameter, peptide release behavior, and swelling behavior,
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Gao, Jinhong, Heng Du, Zhenhong Zhang, et al. "Design and Characterization of Peptide-Based Self-Assembling Microgel for Encapsulation of Sesaminol." Foods 14, no. 6 (2025): 971. https://doi.org/10.3390/foods14060971.

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Sesaminol is a natural functional compound of sesame with low bioaccessibility due to its high crystallinity. Here, a peptide-based self-assembly microgel was constructed to encapsulate sesaminol, reducing its crystallinity and improving its bioaccessibility. In this contribution, the peptide AcNH-Leu-Tyr-Tyr-CONH2 (LYY) was shown to form a mesoporous three-dimensional (3D) microgel through microstructure characterization. Various characterization methods revealed that the LYY peptide self-assembled through β-folds and random coils, and the primary intermolecular interactions arose from hydrog
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Zhang, Zaiyuan, Zhong Chen, Ling Yang, et al. "Platelet Membrane–Encapsulated MSNs Loaded with SS31 Peptide Alleviate Myocardial Ischemia-Reperfusion Injury." Journal of Functional Biomaterials 13, no. 4 (2022): 181. http://dx.doi.org/10.3390/jfb13040181.

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Clinically, antioxidant therapy is a potential strategy for myocardial ischemia-reperfusion injury (MI/RI), a common complication of acute myocardial ischemia. The H-D-Arg-Dmt-Ly-Phe-NH2 (SS31) peptide is shown to have amazing antioxidant properties, but its utilization is limited by the peptide characteristics, such as the destruction by proteases and rapid metabolism. Silica nanoparticles (MSNs) comprise an excellent material for peptide delivery, owing to the protection effect relating to peptides. Moreover, platelet membrane (PLTM) is shown to be advantageous as a coat for nanosystems beca
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Alvarado, Yolanda, Claudia Muro, Javier Illescas, María del Carmen Díaz, and Francisco Riera. "Encapsulation of Antihypertensive Peptides from Whey Proteins and Their Releasing in Gastrointestinal Conditions." Biomolecules 9, no. 5 (2019): 164. http://dx.doi.org/10.3390/biom9050164.

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Antihypertensive peptide fraction from whey protein hydrolysate <3 kDa (measured as angiotensin-converting enzyme (ACE) activity %) was isolated and encapsulated into three composite materials: alginate–collagen, alginate Arabic gum, and alginate–gelatin. The release behavior of peptide fraction from capsules was analyzed according to the encapsulation material efficiency, the characteristics of the capsules, and the released antihypertensive peptides during gastrointestinal digestion. The highest encapsulation efficiency was found in capsules of alginate Arabic gum (95%). In this case, the
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Vashi, Ankur. "Therapeutic Peptides Encapsulated into Lipid-Based Nanovesicles: Scaling from Lab to Plant." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 11 (2024): 1–4. http://dx.doi.org/10.55041/ijsrem38468.

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Lipid-based peptide-encapsulated nanovesicles represent a cutting-edge approach in drug delivery systems, offering enhanced stability, targeted delivery, and controlled release of therapeutic peptides. This review explores the comprehensive science and techniques behind the robust formulation and analytical methods for these nanovesicles, spanning from lab-scale research to large- scale manufacturing. Critical aspects include lipid selection, detailing how the choice of lipids impacts the stability and efficacy of the nanovesicles, and various peptide encapsulation techniques, emphasizing meth
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Dissertations / Theses on the topic "Encapsulated peptide"

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Kilian, Gareth. "Development and testing of liposome encapsulated cyclic dipeptides." Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/1397.

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Cyclic dipeptides have been well characterized for their multitude of biological activities, including antimicrobial and anticancer activities. Cyclo(His-Gly) and cyclo(His-Ala) have also recently been shown to possess significant anticancer activity against a range of cell lines, despite the limitations of these two molecules with respect to their physicochemical properties. Low Log P results in poor cell permeability which can often be problematic for drugs with intracellular mechanisms of action. It can also results in poor biodistribution, and theoretical Log P values for cyclo(His-Gly) an
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McDaniel, Eric B. "Organophosphorus Compound Detection Using Enzyme Encapsulated in Peptide Nanotubes." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1384526146.

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Tshanga, Siphokazi Sisanda. "Antibacterial activity of liposome encapsulated cyclo(TYR-PRO)." Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/1450.

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Cyclic dipeptides (CDPs) are amino acid-based compounds, some of which possess antibacterial activity. The encapsulation of certain drugs into liposomes has been found to improve their activity in terms of bioavailability and duration of action. Liposomes are small vesicles that are under investigation as drug carriers for the delivery of therapeutic agents. A number of liposome formulations are currently under clinical trial review, whilst some have already been approved for clinical use. The aim of this study was to optimize a liposomal cyclo(Tyr-Pro) formulation and to assess its antibacter
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Chang, Lin Chin, and 林志昌. "Development of Thermosensitive Liposome Encapsulated Anti-Cancer Peptide." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/67819635252330825974.

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碩士<br>國立臺灣大學<br>醫學工程學研究所<br>91<br>Abstract In generally, protein / peptide is eliminated by the reticuloendothelial system or degraded by enzyme. Therefore the effectively targeting the functional proteins / functional peptides on the treatment region is a crucial task. By using thermosensitive-liposome combining with hyperthermia , which is a novel trial. Localized hyperthermia in the tumor region results in the Cb1a released from the nontoxic、bio-compatible thermosensitive lipsome, increasing the half-life of CB1a and the accumulation of its dosage within tumor tissues.
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許志榮. "Synthesis of Peptide-Encapsulated Nanoparticles and Application in Fluoroimmunoassays." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/49458354655960542339.

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碩士<br>國立臺灣師範大學<br>化學研究所<br>91<br>We utilized the peptide molecules capping ZnS crystal surface to exchange the organic ligand onto CdSe/ZnS core-shell nanoparticle, that resulted in highly fluorescent, water-soluble one. Various sizes of particles via surface functional group exchange could retain their original morphology and optical property such as UV-VIS absorption, and fluorescent. To covalently attach the peptide-capped nanoparticles to biological macromolecules, we used cross-linker reagent coupling the nanoparticles and antibodys. The particles-labeled antibodys were employed in fluoro
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Raghavender, U. S. "X-Ray Crystallographic Studies Of Designed Peptides : Characterization Of Self-Assembled Peptide Nanotubes With Encapsulated Water Wires And β-Hairpins As Model Systems For β-Sheet Folding". Thesis, 2010. https://etd.iisc.ac.in/handle/2005/1340.

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The study of synthetic peptides aid in improving our current understanding of the fundamental principles for the de novo design of functional proteins. The investigation of designed peptides has been instrumental in providing answers to many questions ranging from the conformational preferences of amino acids to the compact folded structures and also in developing tools for understanding the growth and formation of the protein secondary structures (helices, sheets and turns). In addition, the self-assembly of peptides through non-covalent interactions is also an emerging area of growing intere
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Raghavender, U. S. "X-Ray Crystallographic Studies Of Designed Peptides : Characterization Of Self-Assembled Peptide Nanotubes With Encapsulated Water Wires And β-Hairpins As Model Systems For β-Sheet Folding". Thesis, 2010. http://hdl.handle.net/2005/1340.

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The study of synthetic peptides aid in improving our current understanding of the fundamental principles for the de novo design of functional proteins. The investigation of designed peptides has been instrumental in providing answers to many questions ranging from the conformational preferences of amino acids to the compact folded structures and also in developing tools for understanding the growth and formation of the protein secondary structures (helices, sheets and turns). In addition, the self-assembly of peptides through non-covalent interactions is also an emerging area of growing intere
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Tsai, Ya-Ching, and 蔡雅晴. "IL4-receptor target therapy in colorectal cancer using AP1 peptide-guided liposome-encapsulated doxorubicin." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/13859665618055579957.

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碩士<br>國立陽明大學<br>微生物及免疫學研究所<br>101<br>Colorectal cancer (CRC) has became the most frequently encountered cancer and the third most common cause of cancer-related death in Taiwan since 2007. The cause of CRC mortality is mainly due to the resistance to treatment and the occurrence of distant metastasis, Unfortunately, proximately 45% CRC patients are diagnosed after metastasis. Recent evidences suggest that circulating tumor cell or cancer stem cells could contribute to tumor initiation and metastasis, and confers to drug resistance. Therefore, specifically targeting and killing of these cells c
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趙尹維. "Hydrophobic and hydrophilic drugs encapsulated into CL/PA liposomes conjugated with TAT peptide to protect SK-N-MC cells from β-amyloid peptide-induced degeneration and treat the Alzheimer’s disease rat model". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/z65ht5.

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碩士<br>國立中正大學<br>化學工程研究所<br>105<br>Liposome containing 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), cholesterol, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), cardiolipin (CL) and1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (PA) surface modified with a transactivator of transcription (TAT) peptide was prepared as a carrier for curcumin (CURC), quercetin (QU), rosmarinic acid (RA) and nerve growth factor (NGF) to across blood-brain barrier (BBB) for Alzheimer’s disease (AD) treatment. The particle size and stability of drug-loaded liposome, grafting efficiency and releasing efficiency
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Wang, Cheng-Ting, та 王澄霆. "NGF encapsulated into lactoferrin grafted liposomes for transporting across the blood-brain barrier and counteracting the degeneration of SK-N-MC cells induced apoptosis by β-amyloid peptide". Thesis, 2012. http://ndltd.ncl.edu.tw/handle/99824918269394572452.

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碩士<br>國立中正大學<br>化學工程研究所<br>100<br>In order to improve the low permeability of nerve growth factor (NGF) in the brain. Here, use liposomes as drug carriers which were mixed with saturated phospholipids DPPC and cholesterol. The liposomes encapsulate NGF and surface modified with lactoferrin to increase cellular uptake. Investigating the NGF permeability of the in vitro blood brain barriers (BBB) model was established by human brain microvascular endothelial cells (HBMECs) and human astrocytes (HAs) on the transwell, and the protective effect of NGF against the in vitro Alzheimer’s disease (AD)
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Book chapters on the topic "Encapsulated peptide"

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Ju, Shinyeong, and Cheolju Lee. "Identification of Protein Arginylation by Encapsulated N-Terminal Peptide Enrichment Method." In Methods in Molecular Biology. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2942-0_25.

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Huq, Noorjahan Laila, Keith John Cross, Helen Myroforidis, et al. "Molecular Interactions of Peptide Encapsulated Calcium Phosphate Delivery Vehicle at Enamel Surfaces." In Biomineralization. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1002-7_24.

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Cunha, Carla, Silvia Panseri, and Fabrizio Gelain. "Engineering of a 3D Nanostructured Scaffold Made of Functionalized Self-Assembling Peptides and Encapsulated Neural Stem Cells." In Methods in Molecular Biology. Humana Press, 2013. http://dx.doi.org/10.1007/7651_2012_2.

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Mehrdadi, Soheil. "Solid Lipid Nanoparticles: a promising drug delivery system and their potential for peptide and protein therapeutics." In Dosage Forms - Emerging Trends and Prospective Drug-Delivery Systems [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1005090.

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The discovery of peptide and protein therapeutics such as insulin and adrenocorticotrophic hormone in the twentieth century was a breakthrough in drug discovery. However, peptide and protein therapeutics due to their characteristics are predisposed to denaturation and degradation and their delivery and formulation have been a persistent challenge for the biotech and pharmaceutical industry. Their bioavailability is very low mainly due to low gastrointestinal solubility and permeability resulting from low membrane penetration, high molecular weight, proteolytic chemical and enzymatic degradatio
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Gupta, Anju, Reetu Gupta, and Sudarshan Kurwardkar. "Liposome-Encapsulated Antimicrobial Peptides." In Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering. IGI Global, 2015. http://dx.doi.org/10.4018/978-1-4666-6363-3.ch014.

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The purpose of this chapter is to review the potential use of liposomes and peptides to address the ongoing challenges in infectious diseases involving antimicrobial resistance. The First section of this chapter describes and discusses the use of liposomes as model membrane to gain an insight on the membrane binding and disruption behavior of the potent peptides. Under this section, various biophysical techniques used to characterize the interactions are reviewed. In the second section, the use of antimicrobial peptides as an alternative to conventional antimicrobial therapy is presented. The
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Ross, David. "Condensation Reactions Synthesize Random Polymers." In Assembling Life. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190646387.003.0011.

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Over the past half century of serious research on the origin of life, several schools of thought have emerged that focus on “worlds” and what came first in the pathway to the origin of life. One example is the RNA World, a term coined by Walter Gilbert after the discovery of ribozymes. Other examples include the Iron-Sulfur World of Günther Wächtershäuser and the Lipid World proposed by Doron Lancet and coworkers. Then we have a competition between “metabolism first” and “replication first” schools. The worlds and schools have the positive effect of sharpening arguments and forcing us to think
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Şenel, Behiye, and Gülay Büyükköroğlu. "Nanocarriers for Vaccine and Gene Delivery Application." In Multifunctional Nanocarriers for Contemporary Healthcare Applications. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-4781-5.ch014.

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Nanocarriers with various compositions and biological properties are frequently used systems for in-vitro/in-vivo vaccination and gene transfer. In recent years, developments in nanotechnology have focused on the design and synthesis of nanocarriers that have new properties and can be modified for gene and vaccine delivery. In the favorable results obtained from in-vivo studies performed, they increase interest in these developments and pave the way for their therapeutic use. Nanocarriers have become increasingly important because they can stabilize vaccine antigens and serve as adjuvants, wit
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Singh, Dr Ankita Alice, Dr Seema Kohli, and Dr B. K. Jain. "BACTERIOPHAGE: A NOVEL TOOL FOR THE ERADICATION OF BIOFILM\." In Futuristic Trends in Biotechnology Volume 3 Book 22. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bkbt22p2ch5.

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Biofilms are communities of organisms associated with biotic or abiotic surfaces and encapsulated in extracellular polymers. They form on biotic and abiotic surfaces, including human tissues and medical devices, posing a serious threat to chronic diseases. In addition, current antibiotics and disinfectants have limited ability to completely remove biofilms. In this review, the authors provide an overview of bacterial biofilm formation and its properties, burden, and phage evolution. In addition, recently, phages and phage-derived enzymes used to attack bacteria in the biofilm process have been
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R, Dr Harish, Dr Gururaj Biradar, Mrs Vidhya K S, Dr Ashakiran S, and Dr Kotresh Doddamane. "SNAKE ENVENOMATION & NOVEL THERAPEUTICS." In Futuristic Trends in Medical Sciences Volume 3 Book 12. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bfms12p1ch20.

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Snakes are poikilothermic vertebrates. Snake venom is recognized as one of the most complex toxins found in the world. Comprising a multifaceted blend of peptides, polypeptides, enzymes, glycoproteins, and various other components, snake venom exhibits the potential for a wide range of toxicological impacts. Snakebite envenomation remains a significant global health issue, particularly in regions where venomous snake populations are prevalent. In recent years, the field of nanomedicine has emerged as a promising avenue for overcoming these challenges. This chapter explores the potential of nan
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Khatiwara, Deepika, Bhaskar Jyoti Sharma, Ayoub Hoque, and Manoj Kumar Deka. "ETHOSOMES FOR DRUG DELIVERY OF NATURAL PRODUCTS IN DIABETES." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 3. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bapn3ch13.

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Diabetes mellitus (DM) is the most common metabolic disorder worldwide, brought on by either decreased pancreatic insulin secretion, diminished insulin action in the body, or both. Approximately about 200 million people are currently affected globally with diabetes. Over the past decades, advancements have been madefor the delivery of herbal products through novel approaches such as “Ethosomes”. Ethosomes are composed of phospholipid, alcohol, polyglycol and water. Due to their ease of surface modification, lack of immunogenicity, and ability to efficiently encapsulate both hydrophilic and lip
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Conference papers on the topic "Encapsulated peptide"

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Nikolaeva, V. A., M. Zoughaib, M. I. Kamalov, et al. "CYTOTOXIC AND PROOXIDANT EFFECTS OF AN ANTITUMOR FORMULATION OF MENADIONE BASED ON SOLID LIPID NANOPARTICLES." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-107.

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Solid lipid nanoparticles (SLN) containing encapsulated menadione and modified with L-arginyl-glycyl-L-aspartic acid (RGD) peptide were obtained. The colloidal characteristics of the formulations were studied and their influence on the viability and oxidative status of tumor cells was assessed.
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Xie, Xiaoqi, Debabrata Banerjee, Tamara Minko, et al. "Abstract 5689: Anti-E2F-1 PEGylated liposomal encapsulated peptide regresses human small cell lung cancer & lymphoma xenografts." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5689.

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Kim, Minwook, Isaac E. Erickson, Jason A. Burdick, George R. Dodge, and Robert L. Mauck. "Differential Chondrogenic Potential of Human and Bovine Mesenchymal Stem Cells in Agarose and Photocrosslinked Hyaluronic Acid Hydrogels." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19461.

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Articular cartilage has a limited regenerative capacity, and there exist no methodologies to restore structure and function after damage or degeneration. This has focused intense work on cell-based therapies for cartilage repair, with considerable literature demonstrating that chondrocytes in vitro and in vivo can generate cartilage-like tissue replacements. However, use of primary cells is limited by the amount and quality of autologous donor cells and tissue. Multipotential mesenchymal stem cells (MSCs) derived from bone marrow offer an alternative cell source for cartilage tissue engineerin
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Oehler, Madison, Douglas G. Hayes, and Doris D'Souza. "Encapsulation of Melittin in Bicontinuous Microemulsions for Topical Delivery." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/fmme7461.

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Surgical site infections and chronic wounds, especially those caused by antibiotic-resistant microorganisms, result in hospitalization and fatalities each year. Methods to prevent these infections, such as cleaning and preparing medical tools, have had minimal success in preventing infections. Further, antibiotic treatments have become less successful in treating infections and wounds as a result of antibiotic-resistant bacteria. Antimicrobial peptides (AMP) are a possible treatment solution. AMPs are oligopeptides that occur in nature or can be synthesized in vitro which possess a broad spect
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DRANNIKOV, A. A., A. DI MARTINO, and M. E. TRUSOVA. "RHEOLOGICAL STUDY OF MUCOADHESION OF GRAMICIDIN S: HYDROXYPROPYL-ß- CYCLODEXTRIN INCLUSION COMPLEX AND HOW IT IS AFFECTED BY CHITOSAN." In ФАРМОБРАЗОВАНИЕ-2023 Воронеж. Воронежский государственный университет, 2023. http://dx.doi.org/10.17308/978-5-9273-3827-6-2023-217-221.

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Cyclodextrins became famous for their ability to encapsulate chemical compounds, further modifying their properties. In present research, we focused on the mucoadhesion studies of gramicidin S and how it can be influenced by complex formation with hydroxypropyl-ß-cyclodextrin and chitosan. For the investigation, we applied the rheological method using the rotation viscometer. In accordance with the structural properties, hydroxypropyl-ß-cyclodextrin reduces the mucoadhesion of the peptide while chitosan increases. At the same time, both of these compositions can be considered as a possible way
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Ditto, Andrew J., Nikki K. Robbishaw, Matthew J. Panzner, Wiley J. Youngs, and Yang H. Yun. "Targeting Ovarian Cancer Cells With Rapidly Biodegradable L-Tyrosine Polyphosphate Nanoparticles Decorated With Folate." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53138.

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Chemotherapy employs toxic chemicals to kill rapidly dividing cells. Examples of FDA approved antineoplastic drugs include cisplatin, doxorubicin, and paclitaxel. Since most of these drugs are nonspecific, they also damage normal tissues as well as the aberrant tumors. As a result, non-specific therapies have multiple side effects, which include myelosuppression, mucositis, alopecia, nephrotoxicity, and genotoxcity. In order to minimize these issues, researchers have begun to conjugate antineoplastic chemicals with targeting moieties or encapsulate drugs into nanoparticles decorated with compo
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Yeo, Leslie Y., and James R. Friend. "Surface Acoustic Waves: A New Paradigm for Driving Ultrafast Biomicrofluidics." In ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer. ASMEDC, 2009. http://dx.doi.org/10.1115/mnhmt2009-18517.

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Surface acoustic waves (SAWs), which are 10 MHz order surface waves roughly 10 nm in amplitude propagating on the surface of a piezoelectric substrate, can offer a powerful method for driving fast microfluidic actuation and microparticle or biomolecule manipulation. We demonstrate that sessile drops can be linearly translated on planar substrates or fluid can be pumped through microchannels at typically one to two orders of magnitude faster than that achievable through current microfluidic technologies. Micromixing can be induced in the same microchannel in which fluid is pumped using the SAW
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Sarles, Stephen A., Kevin L. Garrison, Taylor T. Young, and Donald J. Leo. "Formation and Encapsulation of Biomolecular Arrays for Developing Arrays of Membrane-Based Artificial Hair Cell Sensors." In ASME 2011 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2011. http://dx.doi.org/10.1115/smasis2011-5095.

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Recent research in our group has shown that artificial cell membranes formed at the base of a hair-like structure can be used to sense air flow in a manner similar to the mechanotransduction processes found in mammalian hair cells. Our previous work demonstrated that a single artificial hair cell can be formed in an open substrate. However, that study also motivated the need to develop fully-encapsulated devices that feature arrays of hair-cells. Since the transduction element in this concept is an artificial cell membrane, or lipid bilayer, this work investigates two parallel substrate design
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Reports on the topic "Encapsulated peptide"

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Yung, M. C. Engineering a therapeutic microbe for site-of-infection delivery of encapsulated antimicrobial peptides (AMPs). Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/1573149.

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