Relevant bibliographies by topics / Estrogen (17β estradiol)

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Estrogen (17β estradiol)'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Estrogen (17β estradiol)"

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Ansell, P. J., C. Espinosa-Nicholas, E. M. Curran, et al. "In Vitro and in Vivo Regulation of Antioxidant Response Element-Dependent Gene Expression by Estrogens." Endocrinology 145, no. 1 (2004): 311–17. http://dx.doi.org/10.1210/en.2003-0817.

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Abstract Understanding estrogen’s regulation of phase II detoxification enzymes is important in explaining how estrogen exposure increases the risk of developing certain cancers. Phase II enzymes such as glutathione-S-transferases (GST) and quinone reductase protect against developing chemically induced cancers by metabolizing reactive oxygen species. Phase II enzyme expression is regulated by a cis-acting DNA sequence, the antioxidant response element (ARE). It has previously been reported that several antiestrogens, but not 17β-estradiol, could regulate ARE-mediated gene transcription. Our g
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Jayachandran, Muthuvel, Antonio Sanzo, Whyte G. Owen, and Virginia M. Miller. "Estrogenic regulation of tissue factor and tissue factor pathway inhibitor in platelets." American Journal of Physiology-Heart and Circulatory Physiology 289, no. 5 (2005): H1908—H1916. http://dx.doi.org/10.1152/ajpheart.01292.2004.

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Oral estrogen treatment increases thrombotic risk. Tissue factor (TF), tissue factor pathway inhibitor (TFPI), and platelet interaction with leukocytes are important determinants of thrombogenesis. Therefore, the present study was designed to define and compare platelet TF and TFPI mRNA and adhesion protein expression in platelets derived from animals treated with different types of oral estrogens. Ovariectomized pigs were treated with 17β-estradiol (2 mg/day), conjugated equine estrogen (CEE; 0.625 mg/day), or raloxifene (60 mg/day) for 4 wk. Compared with intact animals, ovariectomy and trea
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Moro, Laura, Stefania Reineri, Daniela Piranda та ін. "Nongenomic effects of 17β-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor β and Src kinase". Blood 105, № 1 (2005): 115–21. http://dx.doi.org/10.1182/blood-2003-11-3840.

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Abstract The impact of estrogens on the cardiovascular system and their ability to regulate platelet function are matters of controversy. The recent finding that estrogen receptors are expressed in human platelets renders these cells an excellent model for studying the nongenomic effects of these hormones. In this work, we investigated 17β-estradiol–dependent signaling in platelets from adult healthy men. 17β-estradiol caused the rapid phosphorylation of the tyrosine kinases Src and Pyk2 and the formation of a signaling complex, which included Src, Pyk2, and the phosphatidylinositol 3-kinase.
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Hillerns, Pablo Ibieta, Yuangang Zu, and Michael Wink. "Binding of Phytoestrogens to Rat Uterine Estrogen Receptors and Human Sex Hormone-binding Globulins." Zeitschrift für Naturforschung C 60, no. 7-8 (2005): 649–56. http://dx.doi.org/10.1515/znc-2005-7-823.

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The interaction of phytoestrogens with the most important binding sites of steroid hormones, i.e. sex hormone-binding globulin and estrogen receptors, was investigated. Relative binding affinities and association constants for 21 compounds among them isoflavones, flavones, flavonols, flavanones, chalcones and lignans were determined. The lignan nordihydroguaiaretic acid weakly displaced 17β-[3H]-estradiol from estrogen receptor and Scatchard analysis suggests non-conformational changes. Compounds from Glycyrrhiza glabra, liquiritigenin and isoliquiritigenin, showed estrogenic affinities to bot
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Kennedy, Angela M., Kristen L. Shogren, Minzhi Zhang, Russell T. Turner, Thomas C. Spelsberg та Avudaiappan Maran. "17β-Estradiol-Dependent Activation of Signal Transducer and Activator of Transcription-1 in Human Fetal Osteoblasts Is Dependent on Src Kinase Activity". Endocrinology 146, № 1 (2005): 201–7. http://dx.doi.org/10.1210/en.2004-0486.

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Estrogen is essential for normal growth and remodeling of bone. Although the mechanism of estrogen action on bone cells has been widely investigated, the full spectrum of signal transduction pathways activated by estrogen is unknown. In this report, we investigate the effects of the gonadal hormone 17β-estradiol on the regulation of signal transducer and activator of transcription-1 (Stat1) protein in cultured human fetal osteoblast cells, devoid of the classical estrogen receptors (ERs). 17β-Estradiol (10 nm) led to rapid (within 15 min) activation of Stat1 protein as indicated by increases i
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Culmsee, Carsten, Helmut Vedder, Alexander Ravati, et al. "Neuroprotection by Estrogens in a Mouse Model of Focal Cerebral Ischemia and in Cultured Neurons: Evidence for a Receptor-Independent Antioxidative Mechanism." Journal of Cerebral Blood Flow & Metabolism 19, no. 11 (1999): 1263–69. http://dx.doi.org/10.1097/00004647-199911000-00011.

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Estrogens have been suggested for the treatment of neurodegenerative disorders, including stroke, because of their neuroprotective activities against various neurotoxic stimuli such as glutamate, glucose deprivation, iron, or β-amyloid. Here, the authors report that 17β-estradiol (0.3 to 30 mg/kg) and 2-OH-estradiol (0.003 to 30 mg/kg) reduced brain tissue damage after permanent occlusion of the middle cerebral artery in male NMRI mice. In vitro, 17β-estradiol (1 to 10 μmol/L) and 2-OH-estradiol (0.01 to 1 μmol/L) reduced the percentage of damaged chick embryonic neurons treated with FeSO4. In
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Kaun, Christoph, Gersina Rega, Walter Speidl та ін. "The estrogen metabolite 17β-dihydroequilenin counteracts interleukin-1α induced expression of inflammatory mediators in human endothelial cells in vitro via NF-κB pathway". Thrombosis and Haemostasis 95, № 01 (2006): 107–16. http://dx.doi.org/10.1160/th05-05-0333.

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SummaryIn most studies showing cardio- and vasculoprotective effects of estrogens, 17β-estradiol was used and little information on possible effects of different estrogen metabolites is yet available. We investigated whether particular estrogen metabolites are effective in counteracting inflammatory activation of human endothelium. Human endothelial cells were incubated with 17α-dihydroequilenin, 17β-dihydroequilenin, δ-8,9-dehydroestrone, estrone and 17β-estradiol and stimulated with interleukin (IL)-1α.The expression of IL-6, IL-8 and monocyte chemoattractant protein-1 (MCP-1) was determined
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Cho, JungYoon, Wankyu Park, SeungKi Lee, Woongshick Ahn та YoungJoo Lee. "Ginsenoside-Rb1 from Panax ginseng C.A. Meyer Activates Estrogen Receptor-α and -β, Independent of Ligand Binding". Journal of Clinical Endocrinology & Metabolism 89, № 7 (2004): 3510–15. http://dx.doi.org/10.1210/jc.2003-031823.

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Abstract We studied the estrogenic activity of a component of Panax ginseng, ginsenoside-Rb1. The activity of ginsenoside-Rb1 was characterized in a transient transfection system, using estrogen receptor isoforms and estrogen-responsive luciferase plasmids, in COS monkey kidney cells. Ginsenoside-Rb1 activated both α and β estrogen receptors in a dose-dependent manner with maximal activity observed at 100 μm, the highest concentration examined. Activation was inhibited by the estrogen receptor antagonist ICI 182,780, indicating that the effects were mediated through the estrogen receptor. Trea
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Rodríguez-Landa, Juan Francisco, Oscar Jerónimo Olmos-Vázquez, Carlos Fabrizio Quiñonez-Bailón, et al. "Genistein Reduces Anxiety-like Behavior During Metestrus–Diestrus Phase Without Changing Estradiol or Progesterone Levels in Wistar Rats." Metabolites 15, no. 5 (2025): 311. https://doi.org/10.3390/metabo15050311.

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Background: Premenstrual syndrome is characterized by emotional changes, including anxiety and depression symptoms, which may be treated with anxiolytic and antidepressant drugs, as well as estrogen therapy. However, steroidal estrogen therapy is contraindicated for patients with a potential risk of developing estrogen-dependent cancers through interactions with estrogen receptor α (ERα). Alternatively, genistein produces estrogenic effects in animals and humans at dietary dosages that act on the nuclear and membrane ERα, estrogen receptor β (ERβ), and the G-protein-coupled estrogen receptor (
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Jayachandran, Muthuvel, Rajarshi Mukherjee, Thomas Steinkamp та ін. "Differential effects of 17β-estradiol, conjugated equine estrogen, and raloxifene on mRNA expression, aggregation, and secretion in platelets". American Journal of Physiology-Heart and Circulatory Physiology 288, № 5 (2005): H2355—H2362. http://dx.doi.org/10.1152/ajpheart.01108.2004.

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Changes in platelet functions could contribute to thrombotic risk associated with estrogen treatments. This study was designed to test the hypothesis that three clinically relevant estrogenic treatments affect platelet function comparably. Adult female pigs were ovariectomized and randomized to either no treatment or treatment with oral 17β-estradiol (2 mg/day), conjugated equine estrogen (0.625 mg/day), or raloxifene (60 mg/day) for 4 wk. Platelet turnover, aggregation, and secretion were assessed before and after treatment. Platelet turnover and mRNA increased significantly only in pigs trea
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Dissertations / Theses on the topic "Estrogen (17β estradiol)"

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Brummer, Tyson Peter Thomas. "Comparative Immunological Effects of a Natural Estrogen (17β-estradiol) versus a Pharmacologic Synthetic Estrogen (17α-ethinyl estradiol)". Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/34601.

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Exposure to exogenous estrogens such as synthetic 17α-ethinyl estradiol (EE) occurs via multiple sources (i.e. hormonal contraceptives, environmental contamination, hormone replacement therapy). The natural estrogen, 17β-estradiol (E2), is a well-studied immunomodulatory hormone at both environmental and pharmacologic levels. Conversely, little data exist regarding the immune effects of EE at either environmentally-relevant exposure levels or at pharmacological levels. Further, EE is delivered to patients in a clinical setting via different routes of exposure (e.g. subcutaneous or oral).
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LE, HOA HIEN. "Definition of Rapid 17β-Estradiol Signaling Networks in Developing Cerebellar Granule Cells". University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1218807307.

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Shrestha, Suman Lal. "Fate and Transformation of a Conjugated Natural Hormone 17β-Estradiol-3-Glucuronide in Soil-Water Systems". Diss., North Dakota State University, 2011. https://hdl.handle.net/10365/29317.

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The objectives of the study were to investigate the sorption and degradation of a glucuronide conjugated natural hormone, 17β-estradio1-3-glucuronide (E2-3G), and its estrogenic metabolites in soil-water systems. Radiolabeled E2-3G was first synthesized in the laboratory. Soil-water batch experiments were then conducted using natural and sterilized topsoil (0-6 cm) and subsoil (18-24 cm) with the radiolabeled E2-3G to investigate the effects of soil organic matter content and microbial activity. The aqueous dissipation of 14C in the batch experiments followed a biphasic pattern with an initial
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Qin, Chao. "Mineral Surface Catalyzed Polymerization Of Estrogen And Microbial Deactivation By Fe3+-Saturated Montmorillonite: A Potentially Low Cost Material For Water Decontamination." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/84467.

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With advantages of high cation exchange capacity, swelling-shrinking property and large specific surface area, monmtorillonite is chosen as a carrier and modified with Fe3+ saturation for estrogen decontamination. 17β-Estradiol (βE2) has highest estrogenic activity among estrogens and is selected as representative compound. Rapid βE2 transformation in the presence of Fe3+ - saturated montmorillonite in aqueous system was observed and βE2 oligomers were the major βE2 transformation products. About 98% of βE2 were transformed into oligomers which are >107 times less water-soluble than βE2 and th
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Strand, Magnus. "Estrogen signaling in stroke : genetic and experimental studies." Doctoral thesis, Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1397.

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Bai, Xuelian. "Fate and Transport of an Estrogen Conjugate 17ß-Estradiol-17-Sulfate in Soil-Water Systems." Diss., North Dakota State University, 2013. https://hdl.handle.net/10365/27136.

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The hypothesis of this study was that a sulfate conjugated estrogen, i.e. 17β-estradiol-17- sulfate (E2-17S), could be a precursor to free estrogens detected in the environment. The objectives of were to investigate the fate and transport processes of E2-17S in various soil-water systems. Radiolabeled E2-17S was synthesized using a series of chemical for the subsequent soil batch experiments. The batch experiment results showed that E2-17S dissipated more quickly from the aqueous phase of the topsoil compared to the subsoil, demonstrating that soil organic carbon played a significant role. The
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Scherr, Frank. "Sorption, degradation and transport of estrogens and estrogen sulphates in agricultural soils." Diss., Lincoln University, 2009. http://hdl.handle.net/10182/1017.

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The fate and behaviour of estrogens in the environment are of concern due to the compounds’ endocrine disruption potential. Estrogens, namely 17β-estradiol (E2), estrone (E1), and estrogen sulphates, i.e. 17β-estradiol-3-sulphate (E2-3S) and estrone-3-sulphate (E1-3S) excreted by livestock constitute a potential source for estrogen contamination in the environment. A method was developed to separate and quantify the hormones by high-performance-liquid-chromatography (HPLC) and ultraviolet detection (UV). A combination of dichloromethane (DCM) and dicyclohexylamine hydrochloride (DCH·HCl) gave
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Cookman, Clifford. "Characterization of 17ß-Estradiol Survival Signaling in Medulloblastoma: Relation to Tumor Growth and IGF1 Signaling." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1447158097.

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Nadal, Serrano Mercedes. "Efectos de los Estrógenos, la Genisteína y la Leptina sobre el Estrés Oxidativo en el Cáncer de Mama. Importancia de la UCP2." Doctoral thesis, Universitat de les Illes Balears, 2014. http://hdl.handle.net/10803/284237.

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El estrés oxidativo es un desequilibrio entre la producción de radicales libres y los sistemas antioxidantes encargados de su neutralización. El resultado de este desequilibrio es la acumulación de daños en diversas estructuras celulares incluyendo el DNA. El cáncer se acompaña de un mayor estrés oxidativo a nivel celular, por este motivo, muchos de los tratamientos terapéuticos van dirigidos a aumentar los niveles citotóxicos de ROS, conduciendo a la célula tumoral a la apoptosis. Sin embargo, durante la tumorigénesis las células van adquiriendo una serie de características que permiten mante
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Jijana, Abongile Nwabisa. "Quantum dot sensitized estrogen receptor alpha-recombinant protein electrochemical biosensor for 17-beta estradiol." Thesis, University of the Western Cape, 2016. http://hdl.handle.net/11394/5330.

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Philosophiae Doctor - PhD<br>Estrogens play an extraordinary role in the endocrine system regulation through the stimulation and regulation of endocrine pathways. 17β-estradiol is one of the final metabolites in estrogen regulation by hydroxylase enzymes that are well recognized for their metabolic role in hormone fragmentation and dissociation, through hydroxylation reactions that reversibly convert a series of androgens to estrogens (i.e. or one estrogen to the other). However, the 17β-estradiol hormone has been classified as one of the estrogenic endocrine disrupting compounds {i.e. EDC (s)
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Books on the topic "Estrogen (17β estradiol)"

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Heuer, Barbara. Alternativmethoden zur dünnschichtchromatographischen Trennung des ³H Estradiols von ³H Estron: Bestimmung der 17 [Beta]-Hydroxysteroid Dehydrogenase. [s.n.], 1986.

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Cometti, Barbara Paola Sabrina. Regulatory effects of 17[beta]- estradiol and envrionmental estrogens of bovine oviduct physiology. 2003.

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Book chapters on the topic "Estrogen (17β estradiol)"

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Takami, Shigeru, and Sawa Horie. "Functional Roles of Estradiol in the Olfactory and Vomeronasal Mucosae of Mammals: A Working Hypothesis." In Estrogens - Recent Advances [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106662.

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It has been known that androgens and estrogens, which are referred to as sex steroids, make many effects on two major nasal chemosensory mucosae such as olfactory mucosa and vomeronasal organ. Our studies conducted in rodents have demonstrated that two of the constituent cells in the olfactory mucosa, sustentacular cells and acinar cells in the associated glands of the olfactory mucosa, Bowman’s glands, express four different enzymes involved in the biosynthesis of estradiol-17β (E2). Furthermore, our ongoing study has shown that olfactory sensory cells contain immunoreactivity for an estrogen
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Srivastava, Deepak P., Katherine J. Sellers, and Peter D. Evans. "Rapid Modulation of Spinogenesis by Estradiol in the Neocortex." In Estrogens and Memory. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190645908.003.0005.

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This chapter explores our recent advances in our understanding of how estrogens can modulate spinogenesis within the cortex and its relevance for estrogenic-regulation of cognition. It describes how estrogens, including 17β‎-estradiol and estrogen receptor modulators, rapidly modify dendritic spine density concurrently with influencing cognitive behaviors that require cortical processing. Furthermore, it reviews the evidence that these effects are not limited to female animals but may represent a relevant mechanism in the male brain. This chapter will also explore the emerging role for a novel
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Safe, Stephen. "Transcriptional activation of genes by 17β-estradiol through estrogen receptor-Sp1 interactions." In Vitamins & Hormones. Elsevier, 2001. http://dx.doi.org/10.1016/s0083-6729(01)62006-5.

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Koshkina, Alexandra, Olga Volkova, and Julia Fedotova. "Vitamin D3 Modulates NF-kB/p65, 17β-Estradiol, and Vitamin D Receptors Expression at Estrogen Deficiency." In Vitamin D Deficiency. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.89357.

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Kramár, Enikö A. "Estrogenic Regulation of Synaptic Actin Proteins and Plasticity." In Estrogens and Memory. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190645908.003.0006.

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Estrogens are rapid and potent facilitators of synaptic plasticity in the adult brain; however, the steps that link estrogens to factors that regulate synaptic strength remain unclear. The present chapter will first review the acute effects of 17β‎-estradiol on synaptic transmission and long-term potentiation (LTP). It will then describe a synaptic model used to study the substrates of LTP and provide evidence for the ability of estradiol to rapidly engage a selective actin signaling cascade associated with the consolidation of LTP. Finally, it will be shown that chronic reductions in estradio
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Adkins, Jordan M., Aaron M. Jasnow, and Joseph F. Lynch. "Estradiol and Sex Differences in Generalized Fear." In Estrogens and Memory. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190645908.003.0026.

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In the United States, the prevalence of psychiatric disorders has reached nearly epidemic proportions. Years of research has focused on the link between 17β‎-estradiol and the sex differences observed in anxiety disorders. Evidence suggests that estradiol plays a critical role in the way female rodents and women respond in various tasks assessing anxiety-like behaviors, fear learning, and fear extinction. One hallmark feature of many anxiety disorders is the tendency to express fear to nonthreatening contexts or cues. This generalized fear supports spreading of fear responses and can serve to
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Frick, Karyn M., Jaekyoon Kim, Wendy A. Koss, and Jennifer J. Tuscher. "Molecular Mechanisms Underlying Rapid Effects of Estradiol on Memory Consolidation." In Estrogens and Memory. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190645908.003.0009.

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Research from the past decade has begun to shed light on the neural mechanisms through which the potent estrogen 17β‎-estradiol (E2) regulates the formation of memories. Consolidation is a rapid process which appears to take advantage of the ability of estrogen receptors to quickly trigger cell signaling alterations that increase gene expression, local protein synthesis, and dendritic spinogenesis. This chapter discusses recent advances in understanding how the rapid effects of E2 on the hippocampus influence memory consolidation in female and male rodents and examines new directions for explo
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Koga, Adriana Yuriko, Edmar Miyoshi, João Pedro Gambetta Polay, Bianca Cristina Cardoso, Paulo Vitor Farago, and Leandro Cavalcante Lipinski. "EVALUATION OF HISTOLOGICAL CHANGES IN THE UTERUS OF RATS TREATED WITH ALGINATE FILM CONTAINING 17-Β ESTRADIOL NANOPARTICLES." In Foundations and Frontiers: The Dynamics of Multidisciplinary Sciences. Seven Editora, 2025. https://doi.org/10.56238/sevened2025.021-026.

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OBJECTIVE: This study aims to investigate the effect of film containing 17-β estradiol nanoparticles on uterine tissue. The primary focus is on assessing their potential as precise hormonal therapy for skin lesions in oophorectomized rats. METHODS: The research involved the development of an alginate film containing 17-β estradiol nanoparticles. The animal assay was conducted on oophorectomized rats with dorsal skin lesions measuring 4 cm². The rats were divided into three groups: one treated with the alginate film, the second with a film containing conventional 17-β estradiol, and the third w
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Kato, Asami, Gen Murakami, Yasushi Hojo, Sigeo Horie, and Suguru Kawato. "Rapid Effects of Estradiol on Dendritic Spines and Synaptic Plasticity in the Male and Female Hippocampus." In Estrogens and Memory. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190645908.003.0004.

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Although the potent estrogen, 17β‎-estradiol (E2), has long been known to regulate the hippocampal dendritic spine density and synaptic plasticity, the molecular mechanisms through which it does so are less well understood. This chapter discusses the rapid modulation of hippocampal dendritic spine density and synaptic plasticity in male and female rats, with particular attention to studies in hippocampal slices from male rats. Among the mechanisms described are the roles of specific cell-signaling kinases and estrogen receptors in mediating the effects of E2 and progesterone on hippocampal neu
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Thakkar, Roshni D., Ruimin Wang, Gangadhara R. Sareddy, Ratna K. Vadlamudi, and Darrell W. Brann. "Estrogen Neuroprotection and Anti-Inflammation Actions in the Hippocampus." In Estrogens and Memory. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190645908.003.0024.

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The steroid hormone 17β‎-estradiol (E2) is neuroprotective in several neurodegenerative conditions, including cerebral ischemia, traumatic brain injury, and Alzheimer’s disease (AD). This chapter focuses on the evidence supporting a neuroprotective role of E2 in the hippocampus in cerebral ischemia and AD and reviews various mechanisms thought to underlie E2-induced neuroprotection. Specifically, the chapter discusses the mechanistic role of (a) the various estrogen receptor subtypes, (b) genomic versus nongenomic signaling, (c) regulation of the prosurvival Wnt/β‎−catenin pathway, and (d) ant
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Conference papers on the topic "Estrogen (17β estradiol)"

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Prokić, Danijela, Marija Vukčević, Marina Maletić, et al. "Extraction of Estrogen Hormones from Water Using Carbon Cryogel as Sorbent." In 34th International Congress on Process Industry. SMEITS, 2021. http://dx.doi.org/10.24094/ptk.021.34.1.123.

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In this study, carbon cryogel was used as solid-phase extraction sorbent for the extraction of estrogenic hormones (estrone, 17β-estradiol, and 17α-ethinylestradiol) from water solution. The solid-phase extraction (SPE) method was optimized by choosing an appropriate mass of the sorbent, volume, and initial pH of estrogenic hormone water solution, as well as by choosing an appropriate organic solvent. The concentration of tested hormones after extraction was measured by liquid chromatography coupled with tandem mass spectrometry. Based on the obtained hormone recoveries, the following optimal
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Ghosh, Dipannita, Md Saydur Rahman, Ali Ashraf, and Nazmul Islam. "Graphene Nanoparticle Modified Laser Engraved Kapton Sensor for Environmental Estrogen Detection." In ASME 2023 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/imece2023-114031.

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Abstract In this study, we developed a graphene-based flexible electrochemical immune sensor to rapidly detect 17β-estradiol in phosphate buffer saline (PBS) buffer solution. The irreversible oxidation of the molecule’s phenol group served as the basis for the electrochemical determination of 17β-estradiol. The calculated incubation time of the laser-engraved Kapton sensor with modified graphene polyaniline ink (LEK/G-PANI) is 30 minutes, and the optimum PH level is 7.4. The proposed immune sensor has impedance change with excellent linearity from 0.61 pg/ml to 156.3 pg/ml with a limit of dete
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Mbarik, Maroua, Anissa Belkaid та Marc E. Surette. "Abstract 4419: HER2 expression and 17β-estradiol induce ACSL4 expression in estrogen receptor positive mammary carcinoma cells". У Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-4419.

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Sobrano Fais, R., E. Das Neves Palotta, K. W. Katie та ін. "NLRP3-induced Contractile Dysfunction in Right Ventricle Cardiomyocytes Is Sexually Dimorphic and Modified by 17β-estradiol Via Estrogen Receptor α". У American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4695.

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Mladenović, Milan P., Nevena M. Tomašević, Sanja Lj Matić, Tamara M. Mladenović, and Rino Ragno. "Computer-aided design of new drugs against breast cancer." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.641m.

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Computational medicinal chemistry, if used properly and in accordance with the available experimental data, may provide significant support to rational drug design. Herein, an overview of the computational approaches that have been applied to an estrogen receptor α (ERα) and endowed in the rational design of pM ERα antagonists with profound anti-breast cancer activity either in vitro or in vivo, will be presented. ERα is a 17β-estradiol inducible transcriptional regulator that initiates the RNA polymerase II-dependent transcriptional machinery, pointed for breast cancer (BC) development via ei
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Queiroz, Ana, Paulo Brito, Antonio E. Ribeiro, Eduardo V. Carneiro, and Nathalia S. Foureaux. "OPTIMIZATION OF ESTRADIOL MONITORING IN RAW AND TREATED WASTEWATER SAMPLES BY RESPONSE SURFACE METHODOLOGY." In 22nd International Multidisciplinary Scientific GeoConference 2022. STEF92 Technology, 2022. http://dx.doi.org/10.5593/sgem2022v/3.2/s12.16.

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Estradiol, also designed as 17- ? -estradiol, belongs to the pharmaceutical class of steroid estrogens and was included in the �Watch List� since 2013 the Directive 2013/39/EU due to its potential risk to human health and environment. The low removal efficiency of estrogens by the conventional wastewater treatment plants, becomes a major source of their release into different aquatic matrices. This work presents the optimization of an analytical methodology based on solid phase extraction and high-performance liquid chromatography using the response surface methodology to detect and quantify 1
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Dajić-Stevanović, Zora, Stefan Kolašinac, and Jan Kišgeci. "Phytoestrogens of hops: From expectation to application." In VII naučno-stručni simpozijum sa međunarodnim učešćem "Pivo, pivarske sirovine i tržište". Institute of Field and Vegetable Crops Research, Novi Sad, 2024. https://doi.org/10.5937/pivos24015d.

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Phytoestrogens are compounds occurring in different plant species and in different plant parts, mainly leaves and flowers. These components exhibit an estrogenic activity both in vitro and in vivo conditions. Chemically, they refer to the classes of isoflavones, flavanones, coumestrans and resorcylic acid lactones. Phytoestrogens are known for health beneficial effects in the prevention of breast cancer, post-menopausal syndrome, osteoporosis and atherosclerosis. However, the potency of most of these compounds is relatively low compared to human estrogens (e.g. the 17-estradiol). Hops (Humulus
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Jovanović-Šanta, Suzana S., Esma Isenović, Julijana A. Petrović, and Yaraslau U. Dzichenka. "BINDING OF 17-SUBSTITUTED 16-NITRILE 16,17-SECOESTRANE COMPOUNDS TO ESTROGEN RECEPTORS – „IN VITRO“ AND „IN SILICO“ STUDY." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.403js.

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About 75% of breast cancers express estrogen receptors (ERs), which is a good base for an efficient endocrine therapy. This gives the opportunity for the treatment of patients with antiestrogens, compounds that bind to the ERs and thus compete to estradiol (E2), preventing its action in progression of estrogen-depending cancers. Here we present results of testing the effect of the modified steroids, namely 17-substituted 16-nitrile 16,17-secoestrane compounds on the E2-ER complex forming, its stability, nuclear translocation and binding to DNA. Almost all compounds in moderate to high rate ind
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Liu, Yanghe, Chenguang Sheng, and George Agbai Nnanna. "Detection of Selected Pharmaceutical Contaminants and Removal Efficiency of Emerging Contaminants by Application of Membrane Filtration Technology." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-36906.

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Removal of emerging contaminants is considered to be one of the most important processes within advanced Waste Water Treatment Plants (WWTPs) system. Pharmaceutical contaminants in drinking water could potentially lead to human’s increasing risks of heart attacks, organ damage, mental health and even cancer. This paper investigates the emerging contaminant removal efficiencies of technologies employed by local WWTPs. After determining the presence of selected emerging contaminants (17β-estradiol, Acetaminophen, Carbamazepine, Diclofenac, Erythromycin, Estrone, Bezafibrate, Fluoxetine, Gemfibro
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Lahm, Tim, Marjorie Albrecht, Amanda Fisher, et al. "17-Beta Estradiol (E2) Attenuates Hypoxia-Induced Pulmonary Hypertension Through An Estrogen Receptor-Dependent, But E2 Metabolite-Independent Mechanism." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2521.

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Reports on the topic "Estrogen (17β estradiol)"

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มาลัยวิจิตรนนท์, สุจินดา, та วัชราภรณ์ ติยะสัตย์กุลโกวิท. การศึกษาผลและกลไกการรักษาภาวะกระดูกพรุนของพืชสมุนไพรไทยกวาวเครือขาวในหนูแรท : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2013. https://doi.org/10.58837/chula.res.2013.45.

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การวิจัยนี้เพื่อศึกษากลไกการออกฤทธิ์ของสารไฟโตเอสโตรเจนที่สกัดได้จากกวาวเครือขาวต่อกระบวนการสร้างและสลายกระดูก และการออกฤทธิ์ผ่านตัวรับของฮอร์โมนเอสโตรเจนในเซลล์สร้างกระดูก osteoblast ของหนูแรท ในหลอดทดลอง โดยทำการทดลองในเซลล์ 2 ชนิด คือ osteosarcoma cell line UMR-106 และ primary rat osteoblast cells และให้สาร genistein (GEN) ที่ความเข้มข้น 0.1, 10 และ 1000 nmol/L, puerarin (PU) ที่ความเข้มข้น 1, 10 และ 100 ug/mL นาน 48 ชั่วโมง เทียบผลการทดลองที่ได้กับ 17β-Estradiol ที่ความเข้มข้น 10 nmol/L (กลุ่มควบคุมเชิงบวก) และ 0.3% DMSO (กลุ่มควบคุมเชิงลง) พบว่าสารสกัดกวาวเครือขาวและสารไฟโตเอสโตรเจนที่พบใ
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Tongcharoensirikul, Pakamas. Synthesis of Estrogen Receptor Beta Selective 17-Substituted Estradiols for the Treatment of Prostate Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427891.

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Yaron, Zvi, Abigail Elizur, Martin Schreibman, and Yonathan Zohar. Advancing Puberty in the Black Carp (Mylopharyngodon piceus) and the Striped Bass (Morone saxatilis). United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7695841.bard.

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Both the genes and cDNA sequences encoding the b-subunits of black carp LH and FSH were isolated, cloned and sequenced. Sequence analysis of the bcFSHb and LHb5'flanking regions revealed that the promoter region of both genes contains canonical TATA sequences, 30 bp and 17 bp upstream of the transcription start site of FSHb and LHb genes, respectively. In addition, they include several sequences of cis-acting motifs, required for inducible and tissue-specific transcriptional regulation: the gonadotropin-specific element (GSE), GnRH responsive element (GRE), half sites of estrogen and androgen
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