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Journal articles on the topic 'Estrogenic endocrine disruptors'

Author: Grafiati

Published: 26 July 2023

Last updated: 31 July 2025

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1

Munteanu, Constantin, and Mihai Hoteteu. "Estrogenic compounds – endocrine disruptors." Balneo Research Journal 2, no. 4 (2011): 115–18. http://dx.doi.org/10.12680/balneo.2011.1021.

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Liu, Yan Qun, and Xiong Bing Lu. "Establishing a Assay for Detection of Nonylphenol Estrogenic Effects." Applied Mechanics and Materials 71-78 (July 2011): 3003–6. http://dx.doi.org/10.4028/www.scientific.net/amm.71-78.3003.

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Environmental estrogen could mimic natural estrogens thereby disrupting the endocrine systems of human and animals. The actions of such endocrine disruptors have been studied mainly on reproduction and development. To explore the estrogenic effects of NP by reporter genebased assays we developed. pERE-GFP plamid was generated by inserting estrogen response element fragment into pGADD153-GFP. the recombinant was confirmed by restriction enzyme map and transfected into SPC-A1 cells to ensure the expression of green fluorescent protein．The assay we established in usful, NP could induce the estrog

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Santti, Risto, Sari Mäkelä, Leena Strauss, Johanna Korkman, and Marja-Lsa Kostian. "Phytoestrogens: Potential Endocrine Disruptors in Males." Toxicology and Industrial Health 14, no. 1-2 (1998): 223–37. http://dx.doi.org/10.1177/074823379801400114.

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Exposure to diethylstilbestrol (DES) induces persistent structural and functional alterations in the developing reproductive tract of males. It is possible that xenoestrogens other than DES alter sexual differentiation in males and account for the increasing incidence of developmental disorders of the reproductive tract in men and wild animals. Phytoestrogens (coumestans, isoflavonoids, flavonoids, and lignans) present in numerous edible plants are quantitatively the most important environmental estrogens when their hormonal potency is assessed in vitro. They exert their estrogenic activity by

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Gea, Marta, Chao Zhang, Roberta Tota, Gianfranco Gilardi, Giovanna Di Nardo, and Tiziana Schilirò. "Assessment of Five Pesticides as Endocrine-Disrupting Chemicals: Effects on Estrogen Receptors and Aromatase." International Journal of Environmental Research and Public Health 19, no. 4 (2022): 1959. http://dx.doi.org/10.3390/ijerph19041959.

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Pesticides are widely applied all over the world, and pesticide exposure can induce different biological effects posing a possible threat to human health. Due to their effects on the endocrine system, some pesticides are classified as endocrine disruptors. The aim of the study is to assess the interference of five pesticides on estrogen biosynthesis and estrogen signaling. Three neonicotinoid insecticides (Acetamiprid, Clothianidin, and Thiamethoxam), a carbamate insecticide (Methiocarb) and a herbicide (Oxadiazon) were tested. The effect of pesticides on estrogen biosynthesis was studied thro

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Schooling, C. M., and J. Zhao. "Estrogenic endocrine disruptors and autoimmune disease." International Journal of Epidemiology 44, no. 1 (2014): 363–64. http://dx.doi.org/10.1093/ije/dyu133.

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Kiyama, Ryoiti, and Yuko Wada-Kiyama. "Estrogenic endocrine disruptors: Molecular mechanisms of action." Environment International 83 (October 2015): 11–40. http://dx.doi.org/10.1016/j.envint.2015.05.012.

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Nekvapil, Tomáš, Ivana Borkovcová, Miriam Smutná, and Zdeňka Svobodová. "Estrogenic Profile of the Svratka and Svitava Rivers in the Brno Area." Acta Veterinaria Brno 78, no. 2 (2009): 313–17. http://dx.doi.org/10.2754/avb200978020313.

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Estrogens are chemical compounds considered to be endocrine disruptors. They are thought to affect the endocrine system even at low concentrations found in water (ng l-1). The aim of this work was to determine estrogenic compound levels in the rivers in the Brno area. The concentration of 17β-estradiol, ethynylestradiol, estrone and diethylstilbestrol was estimated in the water samples collected in the Svratka and Svitava rivers. Estrogens were isolated from the samples using solid-phase extraction with Oasis HLB cartridges and determined by means of reversed phase HPLC with UV detection. The

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Lozano-Herrera, Sara Julietta, Nataly García-Gutiérrez, Ana Gabriela Hernández-Puga, Ivan Luzardo-Ocampo, and Haydé Azeneth Vergara-Castañeda. "Estrogenic endocrine disruptors and cancer: a narrative review." Endokrynologia Polska 76, no. 3 (2025): 236–48. https://doi.org/10.5603/ep.104430.

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Manjari, Mishra, Menon N. Gayathri, Sarma V. Tatiparti Sankara, and Mukherji Suparna. "Assessment of endocrine disruption potential of selected pharmaceuticals using an in vitro assay." Journal of Indian Chemical Society Vol. 95, Mar 2018 (2018): 269–78. https://doi.org/10.5281/zenodo.5642064.

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Centre for Environmental Science and Engineering, Centre for Research in Nanotechnology and Science, Department of Energy Science and Engineering, Indian Institute of Technology Bombay, Powai, Mumbai-400 076, India <em>E</em>-<em>mail</em> : manjarimishra1234@gmail.com, gayathrimenon@iitb.ac.in, sankara@iitb.ac.in, mitras@iitb.ac.in <em>Manuscript received 15 November 2017, revised 05 March 2018, accepted 06 March 2018</em> Contamination of water bodies by pharmaceuticals has recently received much attention. Even at low concentration, pharmaceuticals can disrupt the natural hormonal responses

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Wormsbaecher, Clarissa, Andrea R. Hindman, Alex Avendano, Marcos Cortes-Medina, Jonathan W. Song, and Craig J. Burd. "Abstract 2687: The estrogenic activities of endocrine disruptors alter the extracellular matrix and tissue stiffness in the mammary gland." Cancer Research 82, no. 12_Supplement (2022): 2687. http://dx.doi.org/10.1158/1538-7445.am2022-2687.

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Abstract In utero exposure to estrogenic endocrine disrupting compounds (EDCs) increases a woman’s lifetime risk of breast cancer. Similarly, mice exposed in utero to the estrogenic EDC bisphenol A (BPA) have increased susceptibility to mammary gland tumors. It is unclear which BPA-induced alterations predispose the mammary gland to cancer transformation. There is a critical need to understand the mechanisms that drive increased cancer risk in order to assess the impact of BPA and BPA alternatives that retain estrogenic activity. We have utilized in utero BPA exposure as a model system for in

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Sikka, Suresh C., and Run Wang. "Endocrine disruptors and estrogenic effects on male reproductive axis." Asian Journal of Andrology 10, no. 1 (2008): 134–45. http://dx.doi.org/10.1111/j.1745-7262.2008.00370.x.

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12

Doke, Mayur, Vincent Avecilla, and Quentin Felty. "Inhibitor of Differentiation-3 and Estrogenic Endocrine Disruptors: Implications for Susceptibility to Obesity and Metabolic Disorders." BioMed Research International 2018 (2018): 1–16. http://dx.doi.org/10.1155/2018/6821601.

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The rising global incidence of obesity cannot be fully explained within the context of traditional risk factors such as an unhealthy diet, physical inactivity, aging, or genetics. Adipose tissue is an endocrine as well as a metabolic organ that may be susceptible to disruption by environmental estrogenic chemicals. Since some of the endocrine disruptors are lipophilic chemicals with long half-lives, they tend to bioaccumulate in the adipose tissue of exposed populations. Elevated exposure to these chemicals may predispose susceptible individuals to weight gain by increasing the number and size

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Jung, Eui-Man, Beum-Soo An, Hyun Yang, Kyung-Chul Choi, and Eui-Bae Jeung. "Biomarker Genes for Detecting Estrogenic Activity of Endocrine Disruptors via Estrogen Receptors." International Journal of Environmental Research and Public Health 9, no. 3 (2012): 698–711. http://dx.doi.org/10.3390/ijerph9030698.

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14

Chang, Jia, Jianhua Zhou, Mingyang Gao, Hongyan Zhang, and Tian Wang. "Research Advances in the Analysis of Estrogenic Endocrine Disrupting Compounds in Milk and Dairy Products." Foods 11, no. 19 (2022): 3057. http://dx.doi.org/10.3390/foods11193057.

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Milk and dairy products are sources of exposure to estrogenic endocrine disrupting compounds (e-EDCs). Estrogenic disruptors can accumulate in organisms through the food chain and may negatively affect ecosystems and organisms even at low concentrations. Therefore, the analysis of e-EDCs in dairy products is of practical significance. Continuous efforts have been made to establish effective methods to detect e-EDCs, using convenient sample pretreatments and simple steps. This review aims to summarize the recently reported pretreatment methods for estrogenic disruptors, such as solid-phase extr

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Handam, Natasha Berendonk. "Estrogenic activity in reused water: comparison of concentration methods." International Journal of Hydrology 5, no. 3 (2021): 125–30. http://dx.doi.org/10.15406/ijh.2021.05.00274.

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Determining the presence of endocrine disrupting substances in waters is a relevant aspect for monitoring environmental health. Given its relevance, it is important to use methods that can make the total concentration of substances with estrogenic activity (eg endocrine disruptors), being faster, and without the use of compounds that pollute the environment. The purpose of the study was to compare the effectiveness of the methods of concentration by lyophilization and by vacuum concentration of substances with estrogenic activity present in reused water, using the commonly used methodology, so

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K. S., Bhanuprakash, and Deepa kumari G.B. "OPTIMIZING ANIMAL MODELS AND EXPERIMENTAL DESIGNS FOR ENDOCRINE DISRUPTOR RESEARCH AND TESTING." International Journal of Fundamental and Applied Sciences (IJFAS) 10, no. 1 (2021): 4–8. http://dx.doi.org/10.59415/ijfas.v10i1.234.

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Growing evidence suggests that environmental chemicals can disrupt normal endocrine functions, causing developmental and reproductive abnormalities in fish and wildlife. This has raised concerns about potential human health risks. Consequently, US legislation now mandates the Environmental Protection Agency (EPA) to create and validate a screening program to identify chemicals in food and water that may act as endocrine disruptors. In response, the EPA proposed the Endocrine Disruptor Screening Program, which employs both in vitro and in vivo test systems to identify harmful chemicals for huma

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Das, Diptatanu, and Shantanu Das. "Endocrine Disruptor—A threat to the animal world." International Academic Publishing House 24 (April 30, 2021): 10–23. http://dx.doi.org/10.52756/ijerr.2021.v24.002.

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Various types of naturally occurring and artificially made chemicals cause disruption of endocrine processes among animals. They mimic biochemically with hormones and interfere with the normal signaling and activity of the endocrine system, causing enormous changes at the cellular level of animals from lower to higher organisms, including human being. These modified regulations of cellular activities as a result of endocrine disruptors have severe implications at the organismal level. Types and adverse effects of these natural and synthetic agents, especially estrogenic compounds causing biolo

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Ahn, Kyung-Min, Min-Suk Yang, Ha-Kyeong Won, and Jung Ah Lim. "Pilot study: Unveiling the impact of bisphenol A and phthalate exposure on women with asthma." Medicine 103, no. 39 (2024): e39840. http://dx.doi.org/10.1097/md.0000000000039840.

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Endocrine disruptors are considered estrogenic disruptors, and recent researches suggested that they may have a link to the severity of asthma. We aim to validate the correlation between endocrine disruptors and various clinical measurements of asthma, depending on the menopausal status. A pilot case–control study was performed in female asthmatic patients who visited allergy clinic in SMG-SNU Boramae Medical Center. Medical information and the urinary concentrations of 4 endocrine disruptors on their first visit were collected and analyzed: bisphenol A, mono (2-ethyl-5-hydroxyhexyl) phthalate

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Tang, Zi-Run, Xue-Ling Xu, Shou-Long Deng, Zheng-Xing Lian, and Kun Yu. "Oestrogenic Endocrine Disruptors in the Placenta and the Fetus." International Journal of Molecular Sciences 21, no. 4 (2020): 1519. http://dx.doi.org/10.3390/ijms21041519.

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Endocrine disrupting chemicals (EDCs) are exogenous substances that interfere with the stability and regulation of the endocrine system of the body or its offspring. These substances are generally stable in chemical properties, not easy to be biodegraded, and can be enriched in organisms. In the past half century, EDCs have gradually entered the food chain, and these substances have been frequently found in maternal blood. Perinatal maternal hormone levels are unstable and vulnerable to EDCs. Some EDCs can affect embryonic development through the blood-fetal barrier and cause damage to the neu

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Gimiliani, Giovana Teixeira, Roberto Fioravanti Carelli Fontes, and Denis Moledo de Souza Abessa. "Modeling the dispersion of endocrine disruptors in the Santos Estuarine System (Sao Paulo State, Brazil)." Brazilian Journal of Oceanography 64, no. 1 (2016): 1–8. http://dx.doi.org/10.1590/s1679-87592016072806401.

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Abstract Estrogens are hormones responsible for growth and reproduction. They are naturally synthesized by animals and humans alike. Xenoestrogens are identical to natural hormones, but they are man-made and used as oral contraceptives. Xenoestrogens are a specific group of drugs found in domestic wastewater and some environmental matrices. These compounds remain after conventional sewage treatment and, consequently, affect both the environment and non-target aquatic organisms. In this study, we used the Delft3D hydrodynamic model to estimate the amount of both natural and synthetic estrogens

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Prokai, Laszlo, Fatima Rahlouni, Khadiza Zaman, Vien Nguyen, and Katalin Prokai-Tatrai. "Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications." International Journal of Molecular Sciences 22, no. 4 (2021): 1686. http://dx.doi.org/10.3390/ijms22041686.

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The widely used rat uterotrophic assay to assess known and potential estrogenic compounds only considers uterine weight gain as endpoint measurement. To complement this method with an advanced technology that reveals molecular targets, we analyzed changes in protein expression using label-free quantitative proteomics by nanoflow liquid chromatography coupled with high-resolution mass spectrometry and tandem mass spectrometry from uterine protein extracts of ovariectomized rats after daily 17β-estradiol exposure for five days in comparison with those of vehicle-treated control animals. Our disc

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Tanaka, H., Y. Yakou, A. Takahashi, T. Higashitani, and K. Komori. "Comparison between estrogenicities estimated from DNA recombinant yeast assay and from chemical analyses of endocrine disruptors during sewage treatment." Water Science and Technology 43, no. 2 (2001): 125–32. http://dx.doi.org/10.2166/wst.2001.0081.

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This study discusses the estrogenicity and the extent of estrogenic effects, of sewage and treated sewage in public sewage treatment plants in Japan. The estrogenicity in this study was measured with a DNA recombinant yeast strain. Using this method, 43 chemicals that are suspected to have estrogen-like effects were measured and their estrogenicities were evaluated in terms of 17β-estradiol equivalents by comparison with the estrogenicity of 17β-estradiol. 17β-estradiol equivalents of influent and effluent sampled from 20 sewage treatment plants (STPs) were measured with this method. Because t

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Fiocchetti, Marco, Giovanna Bastari, Manuela Cipolletti, Stefano Leone, Filippo Acconcia та Maria Marino. "The Peculiar Estrogenicity of Diethyl Phthalate: Modulation of Estrogen Receptor α Activities in the Proliferation of Breast Cancer Cells". Toxics 9, № 10 (2021): 237. http://dx.doi.org/10.3390/toxics9100237.

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Phthalates comprise a group of synthetic chemicals present in the environment because of their wide use as plasticizers and as additives in products for personal care. Among others, diethyl phthalate (DEP) is largely used in products for infants, children, and adults, in which its exposure has been correlated with an increased risk of breast cancer. The adverse health outcomes deriving from phthalate exposure have been associated with their activity as endocrine disruptors (EDCs) of the steroid and thyroid hormone signaling by affecting developmental and reproductive health, and even carcinoge

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Avecilla, Andrea, Mayur Doke, Jeremy Jovellanos, and Vincent Avecilla. "Contribution of Inhibitor of Differentiation and Estrogenic Endocrine Disruptors to Neurocognitive Disorders." Medical Sciences 6, no. 3 (2018): 61. http://dx.doi.org/10.3390/medsci6030061.

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The devastating growth in the worldwide frequency of neurocognitive disorders and its allied difficulties, such as decline in memory, spatial competency, and ability to focus, poses a significant psychological public health problem. Inhibitor of differentiation (ID) proteins are members of a family of helix-loop-helix (HLH) transcription factors. ID proteins have been demonstrated to be involved in neurodevelopmental and depressive diseases and, thus, may influence neurocognitive deficiencies due to environmental exposure. Previously, it has been demonstrated that environmental factors, such a

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Massart, S., S. Milla, and P. Kestemont. "Evaluation of estrogenic endocrine disruptors effects on rainbow trout (Oncorhynchus mykiss) immunity." Fish & Shellfish Immunology 34, no. 6 (2013): 1723–24. http://dx.doi.org/10.1016/j.fsi.2013.03.268.

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Wagner, Martin, and Jörg Oehlmann. "Endocrine disruptors in bottled mineral water: Estrogenic activity in the E-Screen." Journal of Steroid Biochemistry and Molecular Biology 127, no. 1-2 (2011): 128–35. http://dx.doi.org/10.1016/j.jsbmb.2010.10.007.

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Heinze, John. "Endocrine disruptors in bottled mineral water: Estrogenic activity in the E-Screen." Journal of Steroid Biochemistry and Molecular Biology 127, no. 1-2 (2011): 136–38. http://dx.doi.org/10.1016/j.jsbmb.2011.06.004.

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Křížová, Ludmila, Kateřina Dadáková, Jitka Kašparovská, and Tomáš Kašparovský. "Isoflavones." Molecules 24, no. 6 (2019): 1076. http://dx.doi.org/10.3390/molecules24061076.

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Phytoestrogens are naturally occurring nonsteroidal phenolic plant compounds that, due to their molecular structure and size, resemble vertebrate steroids estrogens. This review is focused on plant flavonoids isoflavones, which are ranked among the most estrogenic compounds. The main dietary sources of isoflavones for humans are soybean and soybean products, which contain mainly daidzein and genistein. When they are consumed, they exert estrogenic and/or antiestrogenic effects. Isoflavones are considered chemoprotective and can be used as an alternative therapy for a wide range of hormonal dis

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Hussain, M. Shakir, and Ajit Kumar Mishra. "Exploring the connection: endocrine disruptors and polycystic ovarian syndrome." International Journal of Basic & Clinical Pharmacology 13, no. 3 (2024): 403–7. http://dx.doi.org/10.18203/2319-2003.ijbcp20241003.

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Polycystic ovarian syndrome (PCOS) is heterogeneous endocrine disorder in females manifesting reproductive dysfunction and metabolic abnormalities. Endocrinopathy in the form of hyperandrogenism leading to alteration in clinical phenotype and fertility seen. Atherogenic dyslipidaemia and insulin resistance as a result of metabolic disturbance also encountered. Recent years, endocrine disrupting chemicals (EDCs) are widely studied and linked for their alleged role in the development of PCOS. EDCs like bisphenol A (BPA), Phthalate, methoxychlor and chlorpyrifos which are present in many industri

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Tabasso, Cassandra, Marie-Pauline Frossard, Camille Ducret, et al. "Transient Post-Natal Exposure to Xenoestrogens Induces Long-Term Alterations in Cardiac Calcium Signaling." Toxics 10, no. 3 (2022): 102. http://dx.doi.org/10.3390/toxics10030102.

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Today, non-communicable disorders are widespread worldwide. Among them, cardiovascular diseases represent the main cause of death. At the origin of these diseases, exposure to challenges during developmental windows of vulnerability (peri-conception, in utero, and early infancy periods) have been incriminated. Among the challenges that have been described, endocrine disruptors are of high concern because of their omnipresence in the environment. Worrisomely, since birth, children are exposed to a significant number of endocrine disruptors. However, the role of such early exposure on long-term

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Kawai, Shin'ichiro, M. Kobayashi, and Hideo Kaneko. "Effects of endocrine active substances in wildlife species: Genetic, biochemical, and physiological factors in variable susceptibility to endocrine disruptors." Pure and Applied Chemistry 75, no. 11-12 (2003): 2335–41. http://dx.doi.org/10.1351/pac200375112335.

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Responses to endocrine active substances (EASs) in animals are various, and differences between the responses among individuals, populations and species are well known. These differences are observed not only in EASs but in most environmental chemicals including synthetic and naturally occurring ones. The basic differences in sensitivity to EASs are attributed to that of affinity or specificity of the receptors to EASs at the cellular level. Although the nucleotide sequences encoding for estrogen receptor proteins have been documented in several species and the functions of the receptors are t

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Briz, V., J. M. Molina-Molina, B. Caballero, et al. "Estrogenic effects of the endocrine disruptors dieldrin, endosulfan and lindane in neuronal cultures." Toxicology Letters 196 (July 2010): S317. http://dx.doi.org/10.1016/j.toxlet.2010.03.1002.

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Kozlowska-Tylingo, Katarzyna, Jacek Namieśnik, and Tadeusz Górecki. "Determination of Estrogenic Endocrine Disruptors in Environmental Samples—A Review of Chromatographic Methods." Critical Reviews in Analytical Chemistry 40, no. 3 (2010): 194–201. http://dx.doi.org/10.1080/10408347.2010.490488.

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Plotan, Monika, Christopher T. Elliott, Caroline Frizzell, and Lisa Connolly. "Estrogenic endocrine disruptors present in sports supplements. A risk assessment for human health." Food Chemistry 159 (September 2014): 157–65. http://dx.doi.org/10.1016/j.foodchem.2014.02.153.

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Wang, Minhao, Hongran Ding, Guiyu Liang, et al. "Occurrence, spatial distribution, risk assessment, and management of environmental estrogens in surface waters of the Taihu basin." Environmental Chemistry 20, no. 8 (2024): 339–53. http://dx.doi.org/10.1071/en23112.

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Environmental context Environmental estrogens can disrupt the normal functioning of endocrine systems, and their occurrence in drinking water sources could cause potential health risk. We investigated concentrations of four estrogens in the lakes from the Taihu Basin, and found that BPA and EE2 were elevated in some sites. However, concentrations of all four environmental estrogens were below the national standards, and caused no health threat to local population. Rationale The Taihu Basin is a critical freshwater ecosystem susceptible to contamination from various anthropogenic activities. En

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Wang, Li-Hsuan, Li-Ru Chen, and Kuo-Hu Chen. "In Vitro and Vivo Identification, Metabolism and Action of Xenoestrogens: An Overview." International Journal of Molecular Sciences 22, no. 8 (2021): 4013. http://dx.doi.org/10.3390/ijms22084013.

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Xenoestrogens (XEs) are substances that imitate endogenous estrogens to affect the physiologic functions of humans or other animals. As endocrine disruptors, they can be either synthetic or natural chemical compounds derived from diet, pesticides, cosmetics, plastics, plants, industrial byproducts, metals, and medications. By mimicking the chemical structure that is naturally occurring estrogen compounds, synthetic XEs, such as polychlorinated biphenyls (PCBs), bisphenol A (BPA), and diethylstilbestrol (DES), are considered the focus of a group of exogenous chemical. On the other hand, nature

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Walker, Benjamin S., Alexander G. Kramer, and Christopher S. Lassiter. "Atrazine affects craniofacial chondrogenesis and axial skeleton mineralization in zebrafish (Danio rerio)." Toxicology and Industrial Health 34, no. 5 (2018): 329–38. http://dx.doi.org/10.1177/0748233718760419.

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Atrazine is a commonly used herbicide that has previously been implicated as an endocrine-disrupting compound. Previous studies have shown that estrogenic endocrine-disrupting compounds affect the development of the heart, cartilage, and bone in zebrafish ( Danio rerio). To determine whether atrazine has effects similar to other endocrine disruptors, zebrafish embryos were treated with a range of atrazine concentrations. Atrazine treatment at a low concentration of 0.1 µM resulted in significant differences in craniofacial cartilage elements, while concentrations ≥1 µM led to decreased surviva

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Espino-Rosales, Diana, Leticia Heras-Gonzalez, Maria J. Jimenez-Casquet, Nicolás Olea, Fátima Olea-Serrano, and Miguel Mariscal-Arcas. "Intake of Phytoestrogens and Estrogenic Effect of the Diet of Female University Students in Mexico." Applied Sciences 15, no. 3 (2025): 1092. https://doi.org/10.3390/app15031092.

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Phytoestrogens are components naturally occurring in plants and include many foods that are part of the regular diet of animals and humans. Phytoestrogens are xenoestrogens of plant origin that are not produced in the endocrine system. Phytoestrogens can act as either agonists or antagonists, depending on their tissue concentrations and the levels of endogenous estrogens at various life stages. The aim was to evaluate the intake of phytoestrogens and the estrogenic effect of the diet of women at university in Chihuahua (Mexico). In total, 400 female university students individually filled out

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Kuwada, Masahiro, Rei Kawashima, Kazuo Nakamura, Hideyo Hasumi, and Jun Maki. "Study of Neonatal Exposure to Estrogenic and Androgenic Endocrine Disruptors by Normal-Phase HPLC." Drug Delivery Letterse 2, no. 2 (2012): 126–31. http://dx.doi.org/10.2174/2210303111202020126.

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Kuwada, Masahiro, Rei Kawashima, Kazuo Nakamura, Hideyo Hasumi, and Jun Maki. "Study of Neonatal Exposure to Estrogenic and Androgenic Endocrine Disruptors by Normal-Phase HPLC." Drug Delivery Letters 2, no. 2 (2012): 126–31. http://dx.doi.org/10.2174/2210304x11202020126.

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Rocha, Maria João, Tânia V. Madureira, Carla Sofia Venade, Irene Martins, Joana Campos, and Eduardo Rocha. "Presence of estrogenic endocrine disruptors in three European estuaries in Northwest Iberian Peninsula (Portugal)." Toxicological & Environmental Chemistry 101, no. 3-6 (2019): 244–64. http://dx.doi.org/10.1080/02772248.2019.1692019.

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Wagner, Martin, and Jörg Oehlmann. "Endocrine disruptors in bottled mineral water: total estrogenic burden and migration from plastic bottles." Environmental Science and Pollution Research 16, no. 3 (2009): 278–86. http://dx.doi.org/10.1007/s11356-009-0107-7.

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Hiramatsu, Naoshi, Takahiro Matsubara, Toshiaki Fujita, Craig V. Sullivan, and Akihiko Hara. "Multiple piscine vitellogenins: biomarkers of fish exposure to estrogenic endocrine disruptors in aquatic environments." Marine Biology 149, no. 1 (2006): 35–47. http://dx.doi.org/10.1007/s00227-005-0214-z.

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Viana, Camila Emanuelle Mendonça, Valquíria dos Santos Lima, Kelly Rodrigues, Luciana Pereira, and Glória Maria Marinho Silva. "Bioremediation of Endocrine Disruptors (EDs): A Systematic Review of Fungal Application in ED Removal from Wastewater." Water 17, no. 5 (2025): 640. https://doi.org/10.3390/w17050640.

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Endocrine disruptors (EDs), including natural estrogens, such as 17β-estradiol (E2) and synthetic chemicals (e.g., bisphenol A (BPA) and per- and polyfluoroalkyl substances (PFAS)), pose environmental and human health risks due to their ability to interfere with hormonal systems, even at trace concentrations and can lead to developmental, reproductive, and carcinogenic effects. These persistent compounds often escape removal in conventional wastewater treatment processes, leading to environmental contamination and human exposure. Given their widespread presence in wastewater and resistance to

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Ruffinatti, Federico Alessandro, Alessandra Gilardino, Valter Secchi, Erika Cottone, Davide Lovisolo, and Patrizia Bovolin. "Bisphenol A Activates Calcium Influx in Immortalized GnRH Neurons." International Journal of Molecular Sciences 20, no. 9 (2019): 2160. http://dx.doi.org/10.3390/ijms20092160.

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Bisphenol A (BPA) is one of the most widely used chemicals worldwide, e.g., as a component of plastic containers for food and water. It is considered to exert an estrogenic effect, by mimicking estradiol (E2) action. Because of this widespread presence, it has attracted the interest and concern of researchers and regulators. Despite the vast amount of related literature, the potential adverse effects of environmentally significant doses of BPA are still object of controversy, and the mechanisms by which it can perturb endocrine functions, and particularly the neuroendocrine axis, are not adequ

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Mallia, Vittoria, Lada Ivanova, Gunnar S. Eriksen, Emma Harper, Lisa Connolly, and Silvio Uhlig. "Investigation of In Vitro Endocrine Activities of Microcystis and Planktothrix Cyanobacterial Strains." Toxins 12, no. 4 (2020): 228. http://dx.doi.org/10.3390/toxins12040228.

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Cyanobacteria are cosmopolitan photosynthetic prokaryotes that can form dense accumulations in aquatic environments. They are able to produce many bioactive metabolites, some of which are potentially endocrine disrupting compounds, i.e., compounds that interfere with the hormonal systems of animals and humans. Endocrine disruptors represent potential risks to both environmental and human health, making them a global challenge. The aim of this study was to investigate the potential endocrine disrupting activities with emphasis on estrogenic effects of extracts from cultures of Microcystis or Pl

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Diamanti-Kandarakis, Evanthia, Jean-Pierre Bourguignon, Linda C. Giudice, et al. "Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement." Endocrine Reviews 30, no. 4 (2009): 293–342. http://dx.doi.org/10.1210/er.2009-0002.

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Abstract There is growing interest in the possible health threat posed by endocrine-disrupting chemicals (EDCs), which are substances in our environment, food, and consumer products that interfere with hormone biosynthesis, metabolism, or action resulting in a deviation from normal homeostatic control or reproduction. In this first Scientific Statement of The Endocrine Society, we present the evidence that endocrine disruptors have effects on male and female reproduction, breast development and cancer, prostate cancer, neuroendocrinology, thyroid, metabolism and obesity, and cardiovascular end

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Martins, Carla, Duarte Torres, Carla Lopes, et al. "Food Consumption Data as a Tool to Estimate Exposure to Mycoestrogens." Toxins 12, no. 2 (2020): 118. http://dx.doi.org/10.3390/toxins12020118.

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Zearalenone and alternariol are mycotoxins produced by Fusarium and Alternaria species, respectively, that present estrogenic activity and consequently are classified as endocrine disruptors. To estimate the exposure of the Portuguese population to these two mycotoxins at a national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering as inputs: i) the food consumption data generated within the National Food and Physical Activity Survey; and ii) the human biomonitoring data used to assess the exposure to the referred mycotoxins. Six models of asso

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El, Helou Myriam, Pascale A. Cohen, Mona Diab-Assaf, and Sandra Ghayad. "Environmental pollutants-dependent molecular pathways and carcinogenesis." BioDiscovery 22 (February 21, 2019): e29242. https://doi.org/10.3897/biodiscovery.22.e29242.

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Exposure to environmental pollutants can modulate many biological and molecular processes such as gene expression, gene repair mechanisms, hormone production and function and inflammation, resulting in adverse effects on human health including the occurrence and development of different types of cancer. Carcinogenesis is a complex and long process, taking place in multiple stages and is affected by multiple factors. Some environmental molecules are genotoxic, able to damage the DNA or to induce mutations and changes in gene expression acting as initiators of carcinogenesis. Other molecules cal

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Leese, Joseph M., Julia McMahon, and Joseph C. Colosi. "Effects of Wastewater Treatment Plant Effluent in a Receiving Stream on Reproductive Behavior of Fathead Minnows (Pimephales promelas)." Fishes 6, no. 2 (2021): 14. http://dx.doi.org/10.3390/fishes6020014.

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Wastewater treatment plant effluents contain a variety of endocrine disrupting chemicals (EDCs), including chemicals with estrogenic activity such as 17β-estradiol (E2), 17α-ethinyl estradiol (EE2), and nonylphenols. These substances can affect both behavior and physiology in vertebrate animals. To explore the presence and effects of these EDCs in a natural setting, juvenile and adult male fathead minnows, Pimephales promelas, were held in cages upstream and downstream of the effluent site of a wastewater treatment plant for 21 days and subsequently tested for changes in reproductive behaviors

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