Academic literature on the topic 'Eudragit RL100'

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Journal articles on the topic "Eudragit RL100"

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Mohapatra, P. K., C. H. Nagalakshmi, V. Tomer, et al. "Formulation and in Vitro Evaluation of Controlled Release Transdermal Drug Delivery System of Simvastatin A Model Hypocholesterolemia Drug." International Journal of Current Pharmaceutical Review and Research 9, no. 5 (2018): 71–76. https://doi.org/10.5281/zenodo.12674097.

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The intention of this research work was to develop a matrix-type transdermal drug delivery system (TDDS) containingsimvastatin an antilipidemic drug with different ratios of hydrophilic HPMC K100M and hydrophobic Eudragit RL100 &Eudragit RS100 polymers with surfactant Tween 80 and plasticizer glycerin by the solvent evaporation technique. Theprepared films were evaluated for physicochemical properties. Matrix films were evaluated for their physicochemicalcharacterization followed by in-vitro evaluation. The drug released rate was found to be increased when the concentrationof the polymer d
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Šveikauskaitė, Indrė, and Vitalis Briedis. "Effect of Film-Forming Polymers on Release of Naftifine Hydrochloride from Nail Lacquers." International Journal of Polymer Science 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/1476270.

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The successful topical therapy of onychomycosis depends on effective drug release and penetration into nail, which can be achieved by using an adequately developed delivery system. This study evaluated and compared effect of film-forming polymers Eudragit RL100, Eudragit RS100, and ethyl cellulose on naftifine hydrochloride release from experimental nail lacquer formulations. Quality of formulations was evaluated by determining drying time and water resistance. Interactions between active pharmaceutical ingredient and excipients were investigated using microcalorimetry and FT-IR. Optimization
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Dr.E, Hari Krishna T. Mallika *. DS Spandana M. Harika Raj S. Jyothi. "DEVELOPMENT AND EVALUATION OF METFORMIN HCL LOADED EUDRAGIT®RSPO AND EUDRAGIT®RLPO AND GLIMEPIRIDE BILAYER TABLETS." Indo American Journal of Pharmaceutical Sciences 04, no. 09 (2017): 3371–80. https://doi.org/10.5281/zenodo.1000995.

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The present study was carried out for developing the formulation of Bilayer tablets of Glimepiride, Metformin HCl. Immediate Release (IR) layer was compressed as direct compression method and Sustained Release (SR) layer blends were compressed by wet granulation method. IR and SR layers were evaluated for pre and post compression studies and all studies were found to be within limits. From dissolution data of Glimepiride Immediate release layer, IR5 formulation was shown maximum drug release at 60 min i.e., 96.4%. Hence IR5was concluded as optimised formulation for IR layer. Sustained layer co
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Tiwari, Ruchi, Birendra Srivastava, Gaurav Tiwari, and Awanik Rai. "Extended release promethazine HCl using acrylic polymers by freeze-drying and spray-drying techniques: formulation considerations." Brazilian Journal of Pharmaceutical Sciences 45, no. 4 (2009): 829–40. http://dx.doi.org/10.1590/s1984-82502009000400029.

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The present study investigated a novel extended release system of promethazine hydrochloride (PHC) with acrylic polymers Eudragit RL100 and Eudragit S100 in different weight ratios (1:1 and 1: 5), and in combination (0.5+1.5), using freeze-drying and spray-drying techniques. Solid dispersions were characterized by Fourier-transformed infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC), Powder X-ray diffractometry (PXRD), Nuclear magnetic resonance (NMR), Scanning electron microscopy (SEM), as well as solubility and in vitro dissolution studies in 0.1 N HCl (pH 1.2), double-d
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Patil, Pravin S., and Shashikant C. Dhawale. "DEVELOPMENT OF RITONAVIR LOADED NANOPARTICLES: IN VITRO AND IN VIVO CHARACTERIZATION." Asian Journal of Pharmaceutical and Clinical Research 11, no. 3 (2018): 284. http://dx.doi.org/10.22159/ajpcr.2018.v11i3.23145.

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Objective: The purpose of the present investigation was to develop a nanosuspension to improve dissolution rate and oral bioavailability of ritonavir.Methods: Extended-release ritonavir loaded nanoparticles were prepared using the polymeric system by nanoprecipitation technique. Further, the effect of Eudragit RL100 (polymeric matrix) and polyvinyl alcohol (surfactant) was investigated on particle size and distribution, drug content, entrapment efficiency, and in vitro drug release from nanosuspension where a strong influence of polymeric contents was observed. Drug-excipient compatibility and
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Shinde, Ujwala A., Jaykumar N. Shete, Hema A. Nair, and Kavita H. Singh. "Eudragit RL100 based microspheres for ocular administration of azelastine hydrochloride." Journal of Microencapsulation 29, no. 6 (2012): 511–19. http://dx.doi.org/10.3109/02652048.2012.665088.

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Bucolo, Claudio, Adriana Maltese, Francesco Maugeri, Barbara Busà, Giovanni Puglisi, and Rosario Pignatello. "Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene." Journal of Pharmacy and Pharmacology 56, no. 7 (2004): 841–46. http://dx.doi.org/10.1211/0022357023835.

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Pandey, Vivek Kumar, Kumar Rohit Srivastava, Gufran Ajmal, et al. "Differential Susceptibility of Catheter Biomaterials to Biofilm-Associated Infections and Their Remedy by Drug-Encapsulated Eudragit RL100 Nanoparticles." International Journal of Molecular Sciences 20, no. 20 (2019): 5110. http://dx.doi.org/10.3390/ijms20205110.

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Biofilms are the cause of major bacteriological infections in patients. The complex architecture of Escherichia coli (E. coli) biofilm attached to the surface of catheters has been studied and found to depend on the biomaterial’s surface properties. The SEM micrographs and water contact angle analysis have revealed that the nature of the surface affects the growth and extent of E. coli biofilm formation. In vitro studies have revealed that the Gram-negative E. coli adherence to implanted biomaterials takes place in accordance with hydrophobicity, i.e., latex > silicone > polyurethane &gt
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H. Hussain, Ahmed, and Yehia I.Khalil. "Some Variables Affecting the Formulation of Pentoxifylline (PTX) as a Solid Sustained Release Dosage Form." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 17, no. 1 (2017): 1–6. http://dx.doi.org/10.31351/vol17iss1pp1-6.

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An inert matrix that is used to control the release of (PTX) was prepared using Eudragit RL100 and RSPM types as matrix forming agent . The matrices were prepared by either dry granulation(slugging) , or wet granulation method using chloroform as a solvent evaporation vehichle. The cumulative release was adjusted by using polyvinylpyrollidone (PVP) or ethylcellulose (EC) polymers .The results indicated that both methods of preparation were valid for incorporation PTX as a sustained release granules .Moreover ,the results revealed that best polymer used was Eudragit RSPM in 3:20 polymer drug ra
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Noor, Amjed H., and Mowafaq M. Ghareeb. "Formulation and Evaluation of Ondansetron HCl Nanoparticles for Transdermal Delivery." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 29, no. 2 (2020): 70–79. http://dx.doi.org/10.31351/vol29iss2pp70-79.

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Ondansetron HCl (OND) is a potent antiemetic drug used for control of nausea and vomiting associated with cancer chemotherapy. It exhibits only 60 – 70 % of oral bioavailability due to first pass metabolism and has a relative short half-life of 3-5 hours. Poor bioavailability not only leads to the frequent dosing but also shows very poor patient adherence. Hence, in the present study an approach has been made to develop OND nanoparticles using eudragit® RS100 and eudragit® RL100 polymer to control release of OND for transdermal delivery and to improve patient compliance.
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Dissertations / Theses on the topic "Eudragit RL100"

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Mandal, Bivash. "Preparation and Physicochemical Characterization of Eudragit® RL100 Nanosuspension with potential for Ocular Delivery of Sulfacetamide." University of Toledo / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1271430956.

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