Academic literature on the topic 'Excision margins'

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Journal articles on the topic "Excision margins"

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Subhas, Gokulakkrishna, Asha J. Shah, Aditya Gupta, et al. "Review of Third and Fourth Re-Excision for Narrow or Positive Margins of Invasive and Intraductal Carcinoma." International Surgery 96, no. 1 (2011): 18–20. http://dx.doi.org/10.9738/1340.1.

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Abstract The trend in breast surgery has shifted toward breast conservation. We reviewed our third and fourth breast re-excision cases, with an analysis of various factors used in making this decision. A retrospective analysis identified 585 patients who underwent re-excision surgery for positive or close margins of invasive carcinoma or ductal carcinoma in situ (DCIS). Of these patients 75 (13%) and 17 (3%) underwent third and fourth re-excisions, respectively. The indication for a third re-excision was the presence of positive and/or close (≤1 mm) margins for invasive carcinoma or DCIS in 72
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Ozmen, V., S. Ozkan Gurdal, M. Muslumanoglu, et al. "Predictive factor for residual tumor after lumpectomy for close margins." Journal of Clinical Oncology 27, no. 15_suppl (2009): e11538-e11538. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e11538.

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e11538 Background: It is critical to obtain clear margins to minimize local recurrence after breast conserving surgery(BCS). When re-excisions are performed, there is often no residual disease in the new specimen, calling into question the need for re-excision(s) or mastectomy. The aim of the present study was to identify factors predicting a histologically positive re-excision specimen. Methods: Our prospective breast cancer database was queried for all invasive breast cancer patients who underwent a re-excision lumpectomy for either close or positive margins after an attempt at BCS. Close ma
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Semple, Harriet K., and Marc J. Langbart. "Margin of error: accuracy of estimated excision margins by surgical experience." Australasian Journal of Plastic Surgery 5, no. 1 (2022): 13–16. http://dx.doi.org/10.34239/ajops.v5n1.257.

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Guidelines for recommended margins for common lesions are well documented. While it is recommended that all margins be measured prior to excision, time pressures, lack of equipment or clinician confidence may result in margins that are estimated rather than formally measured. This increases the risk of involved margins and need for re-excision to prevent recurrence. We reviewed the estimated margins of common excisions and compared these between groups of different surgical experience. We found that while accuracy generally improves with surgical experience, margins are largely underestimated
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O’Connell, L., S. Walsh, D. Evoy, et al. "The approach to an isolated close anterior margin in breast conserving surgery." Annals of The Royal College of Surgeons of England 101, no. 4 (2019): 268–72. http://dx.doi.org/10.1308/rcsann.2019.0017.

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Introduction Although close radial margins after breast-conserving surgery routinely undergo re-excision, appropriate management of patients with close anterior margins remains a topic of controversy. An increasing body of literature suggests that re-excision of close anterior margins yields low rates of residual malignancy and may only be necessary in selected patients. The aim of this study was to examine the management of close anterior margins after breast conserving surgery in a single institution and to analyse the rate of residual disease in re-excised anterior margins. Methods All pati
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Ghosh, S., S. Duvvi, P. Goodyear, E. Reddy, and A. Kumar. "Evaluation of surgeons' marking of excision margins for superficial facial skin cancer lesions." Journal of Laryngology & Otology 123, no. 2 (2008): 195–98. http://dx.doi.org/10.1017/s0022215108002612.

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AbstractIntroduction:We established a series of exercises that evaluated surgeons' marking of excision margins, and we sought to identify factors influencing such marking.Methods:Twenty-four participants were asked to draw preset margins (3, 4, 5, 8 or 10 mm) on a series of life-size images representing noncosmetically and cosmetically sensitive facial sites, and also to draw circles of set diameters (3, 5 and 8 mm) on white paper. Margins were measured with vernier callipers calibrated to 0.05 mm.Results:In the small margin (3 mm) and noncosmetically sensitive exercises, the mean margins draw
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Adkison, Michael, Andrew Armenta, Frank Winsett, and Richard Wagner. "Review of Tumor Margins for Lentigo Maligna with Staged Surgical Excision and Permanent Section en face Processing." SKIN The Journal of Cutaneous Medicine 8, no. 4 (2024): 1672–80. http://dx.doi.org/10.25251/skin.8.4.5.

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Background: The optimal surgical margins required for the excision of lentigo maligna remains a topic of debate. Recent literature suggests that wider margins are warranted. Objective: Comparison of lentigo maligna margin sizes and clearance rates from a single center to existing literature. Methods: A retrospective analysis of primary and recurrent lentigo maligna treated by staged excision with complete circumferential and deep margin assessment between 2011 and 2023 at a single institution was conducted. The percentage of tumors with clear margins after the initial excision with 5 mm margin
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Sebastian, Mary L., Alice Marie Police, Stephanie Akbari, and Beth Anglin. "Combined experience at three breast centers with routine use of an intraoperative margin assessment device including comparison to historical re-excision rates." Journal of Clinical Oncology 32, no. 26_suppl (2014): 79. http://dx.doi.org/10.1200/jco.2014.32.26_suppl.79.

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79 Background: Historically there has been a high rate of surgical interventions to obtain clear margins for breast cancer patients undergoing breast conserving local therapy. This study is the first compellation of data among three breast centers to assess the impact of an intraoperative margin assessment tool (MarginProbe) on re-excision rates. This device has been approved for clinical use in the United States since 2013. We present groups of consecutive patients in each of these breast centers – before and after the implementation of routine intraoperative use of the margin assessment devi
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Lupu, Mihai, Vlad Mihai Voiculescu, Ana Caruntu, Tiberiu Tebeica, and Constantin Caruntu. "Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma." Diagnostics 11, no. 1 (2021): 120. http://dx.doi.org/10.3390/diagnostics11010120.

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Complete removal of malignant skin lesions with minimal impact on the aesthetic and functional aspects is the ideal of every dermatologic surgeon. Incomplete surgical excisions and tumor recurrences of basal cell carcinomas (BCC) commonly occur due to the subclinical extension of tumor lateral margins. Presently, the lateral excision margins for BCC cannot be objectively assessed preoperatively, dermoscopy proving to be relatively inefficient in this respect. The question is whether BCC lateral excision margins can be precisely determined preoperatively through the use of complementary non-inv
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Martin, Luke, Miguel S. Cabalag, Anand Ramakrishnan, and Andrew Martin. "Management of close/positive margins in cutaneous squamous cell carcinoma of the head and neck: a systematised review." Australasian Journal of Plastic Surgery 7, no. 2 (2024): 1–13. http://dx.doi.org/10.34239/ajops.88849.

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Introduction: The authors reviewed close/positive margins in cutaneous squamous cell carcinoma of the head and neck, ensuing recurrence, regional or systemic metastasis, mortality and follow-up management. Methods: The design was a systematised review from January 2000 to July 2021. The MEDLINE database was searched with 15 articles out of 3104 meeting the inclusion criteria. Pertinent references underpinning the National Comprehensive Cancer Network’s Squamous Cell Skin Cancer Guidelines Version 2.2022 were reviewed. Results: Overall, there were 13,671 cutaneous squamous cell carcinoma lesion
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Schnabel, Freya Ruth, Shira Schwartz, Deirdre Kiely, and Jennifer Chun. "Improving breast-conserving surgery: A focus on margins." Journal of Clinical Oncology 31, no. 31_suppl (2013): 127. http://dx.doi.org/10.1200/jco.2013.31.31_suppl.127.

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127 Background: Inadequate lumpectomy margins are associated with an increased risk of ipsilateral recurrence in patients undergoing breast conserving surgery for cancer. Multiple procedures are often required to achieve acceptable margins, increasing the burden to the patient and the health care system, and potentially delaying other adjuvant treatments. A novel device for intraoperative assessment of lumpectomy margins (MarginProbe) has been associated with a 25% reduction in the rate of positive margins at the conclusion of primary lumpectomy surgery. Our aim was to establish a baseline re-
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Dissertations / Theses on the topic "Excision margins"

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Nashidengo, Pueya Mekondjo. "Five-year review of breast-conserving therapy (BCT) for breast carcinoma: Surgical margins, re-excision and local recurrence in a single tertiary center." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/24506.

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Background: Breast cancer burden is on the increase in the developing world. Breast-conserving therapy (BCT) is prescribed for early breast cancer. It is the wide local excision of the tumour usually followed by radiation treatment to the breast. It is the mainstay treatment for carefully selected patients with early breast cancer presenting to the Groote Schuur Hospital's Oncology and Endocrine Surgical unit, Cape Town South Africa. There has not been a formal audit to review the outcomes of BCT in the unit. Objectives: The objective of this study is to determine and analyse the excision marg
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Milan, Ranisavljević. "Дијагностичка вредност мобилне дигиталне радиографије у процени позитивности ресекционих хируршких маргина код карцинома дојке". Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2020. https://www.cris.uns.ac.rs/record.jsf?recordId=114074&source=NDLTD&language=en.

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Karcinom dojke predstavlja najčešću malignu neoplazmu među ženskom populacijom, a poštedna terapija dojke, preferirani je model lečenja bolesnica u ranom stadijumu bolesti. Smatra se da je optimalna hirurška resekciona margina 2 mm. Opisano je mnogo metoda koje služe za intraoperativnu proveru suficijentnosti resekcione hirurške margine i sve one imaju svoje prednosti i mane. Ciljevi ove studije bili su da se utvrdi, da li postoji statistički značajna razlika u određivanju širine negativne resekcione hirurške margine izražene u milimetrima pri operacij
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Roussel, Lucas. "Diagnostiquer le cancer de l'ovaire grâce à la technologie SpiderMass." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. https://pepite-depot.univ-lille.fr/ToutIDP/EDBSL/2023/2023ULILS121.pdf.

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Les cancers de l'ovaire (OC) sont les cancers gynécologiques les plus mortels, entraînant plus de 200 000 décès chaque année dans le monde. Le diagnostic de ces cancers reste difficile et un diagnostic tardif entraîne un retard de prise en charge du patient réduisant alors ses chances de survie. Pour répondre à ce besoin clinique, nous avons développé un outil de diagnostic et pronostic en temps réel : le SpiderMass. Dans un premier temps, pour permettre un diagnostic précoce et une action préventive, nous nous sommes intéressés à l'origine du sous-type d'OC le plus agressif : le cancer séreux
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Addae, Haleema. "The impact of positive margins and crypt involvement in excisional procedures of the cervix on recurrence rates of premalignant diseases of the cervix." Master's thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/33427.

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BACKGROUND Recurrent disease after cervical excisional procedures has been linked to many factors. We aim to determine if positive margins and crypt involvement increased the rate of recurrence of premalignant disease in patients who had excisional procedures. METHODS In this retrospective review of the colposcopy database, patient records and pathology database, women who had cervical excisional procedures at the Groote Schuur Hospital colposcopy clinic in 2010 were followed up until 2015. Recurrence was based on high grade cytology or histology at follow up. Chi-square tests were used to com
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Henriques, Valéria José Gonçalves. "Margem cirúrgica no melanoma: Que evidência?" Master's thesis, 2021. http://hdl.handle.net/10316/98308.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: O melanoma cutâneo é uma neoplasia maligna com origem nos melanócitos. Ocorre com maior frequência em caucasianos de pele clara e com dificuldade em bronzear. O tratamento de primeira linha é a excisão cirúrgica da lesão com margens de segurança que variam de acordo com o índice de Breslow. Com este trabalho pretende-se perceber se será mesmo necessário adaptar a abordagem cirúrgica ou se, pelo contrário, todos os melanomas poderão ser excisados com a mesma margem de segurança, independentemente
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Noel, Carolyn Joyce. "Excision margins in human immunodeficiency virus seropositive women undergoing large loop excision of the transformation zone for cervical dysplasia." Thesis, 2015. http://hdl.handle.net/10539/18505.

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Department of Obstetrics and Gynaecology University of the Witwatersrand Johannesburg February 2015 A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Masters in Medicine, in the branch of Obstetrics and Gynaecology.<br>HIV accelerates the development of cervical cancer by up to15 years. South Africa is currently in the midst of an HIV epidemic. With limited facilities for colposcopy it is vital to identify risk factors within the HIV positive population resulting in posit
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Chang, Chih-chia, and 張志嘉. "3D US imaging in margin evaluation for malignant breast tumor excision using Mammotome." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/21209706983904264104.

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碩士<br>國立中正大學<br>資訊工程研究所<br>90<br>In this paper, we use the 3D ultrasound dataset for evaluating the malignant breast tumor contour and the excision margin after the surgical operation called Mammotome. And the result can help the physician evaluating the surgical outcome. The 3D ultrasound dataset is composed of a series of 2D images, however, the traditional 2D image segmentation methods can’t extract reasonable contour due to the characteristics of ultrasound — noises and speckles. We proposed a modified edge-based segmentation method for finding the contour in this paper. By using anisotrop
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曾姿綺. "3D snake for US in margin evaluation for malignant breast tumor excision using mammotome." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/95264239380961050796.

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Books on the topic "Excision margins"

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Glynn Bolitho, D. Tumours and hand reconstruction. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.006012.

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♦ Hand tumours are common♦ The vast majority are benign♦ Soft tissue – commonest Giant cell tumour of tendon sheath. Treatment marginal excision♦ Bone – commonest – Enchondroma. Treatment – leave if incidental or currette +/− bone grafting♦ Malignant – need full work up with detailed clinical examination, investigation, and planning in a multidisciplinary meeting♦ Treatment is wide/radical excision often with partial amputation +/− plastic surgical reconstruction.
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Book chapters on the topic "Excision margins"

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Ferrari, Marco, Nausica Montalto, and Piero Nicolai. "Novel Approaches in Surgical Management: How to Assess Surgical Margins." In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63234-2_7.

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AbstractThe concept of surgical margins was born a long time ago but still lacks a univocal and sound understanding. The current biological rationale behind the recommendations on margins management relies on two pillars: (1) the observation that groups of cancer cells can leave the macroscopic tumor and disseminate throughout adjacent tissues with different degrees of aggressiveness; (2) the belief that removal of all (or most of) cancer cells can cure the patient. However, this background is undermined by some pieces of evidence. For instance, it has been proven that tissues surrounding canc
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Wu, James S., Homer O. Wiland, and Eric W. Willis. "Perianal (Anal Margin) Squamous Cell Carcinoma-Local Excision." In Cleveland Clinic Colorectal Case Studies. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-39880-3_38.

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Leedy, Jason E., and James S. Wu. "Perianal (Anal Margin) Squamous Cell Carcinoma-Local Excision with Fasciocutaneous Flap Reconstruction." In Cleveland Clinic Colorectal Case Studies. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-39880-3_39.

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Gareau, Daniel S., Kishwer Nehal, and Milind Rajadhyaksha. "Confocal Mosaicing Microscopy in Skin Excisions: Feasibility of Cancer Margin Screening at the Bedside to Guide Mohs Surgery." In Reflectance Confocal Microscopy for Skin Diseases. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-21997-9_33.

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Cody, Hiram. "Re-Excision of Margins." In Atlas of Procedures in Breast Cancer Surgery. CRC Press, 2005. http://dx.doi.org/10.3109/9780203491645-9.

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Tsabazis, Nikolaos, Anastasia Vatopoulou, and Angelos Daniilidis. "Non-Free Surgical Margins After LLETZ-LEEP." In Handbook of Research on Oncological and Endoscopical Dilemmas in Modern Gynecological Clinical Practice. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-4213-2.ch010.

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Large Loop Excision of the Transformation Zone (LLETZ) is thought to be the treatment of choice for the high-grade precancerous lesions. The cone is also the “gold standard” specimen for the diagnosis of the underlying cervical disease once it includes the entire area of carcinogenesis for the squamous epithelium (transformation zone). In most research studies, therapeutic success after conization is a term generally assigned for disease clearance, that is, absence of residual high grade/CIN2+ histology by the end of a reasonable follow-up period, aiming at risk reduction for future recurrence
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Gruber, Elizabeth A. "Excision Margins in High-Risk Malignant Melanoma." In 50 Landmark Papers every Oral & Maxillofacial Surgeon Should Know. CRC Press, 2020. http://dx.doi.org/10.1201/9780429288036-37.

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Patel, Dr Prachi, Dr Bhupesh Patel, Dr Himani Tiwari, and Dr Rina Mehta. "UNICYSTIC AMELOBLASTOMA." In Futuristic Trends in Medical Sciences Volume 3 Book 15. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bams15p1ch2.

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Unicystic ameloblastoma (UA) is a monocystic lesion having odontogenic epithelium. UA arises from the epithelial remains of Malassez of Hertwig’s epithelial sheath. It usually affects men more than women and appears common in 20 to 30 years of age. Clinically, it is asymptomatic, although it can induce swelling and facial asymmetry by expanding the bony cortex and permitting soft tissue invasion. Chances of invasion and recurrence are more in this as compared to conventional ameloblatoma. UA has a well-defined, radiolucent, unilocular on radiographs, and histologically, it can be luminal, intr
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Angus, Bill. "Literature: Liminal Ground in Early Modern Drama." In A History of Crossroads in Early Modern Culture. Edinburgh University Press, 2022. http://dx.doi.org/10.3366/edinburgh/9781474499828.003.0006.

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In Shakespeare’s lifetime and long after, to live as a traitor or to die in suicide meant, in burial, to be treated as refuse. It is probable that Shakespeare knew at least five such people, disposed of in a ceremony whose elements were, as described in the last chapter, the night, the crossroads, and the stake. Although he largely avoids depicting subjects like imprisonment and execution, the question of outcast burial nevertheless emerges in hints and allusions found in the plays, like the shadowy revenants of unquiet thoughts. Contrastingly, George Peele is the one dramatist of the era who
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Scase, Tim. "What your pathologist does with your sample and how they assess margins of tumour excision." In BSAVA Congress Proceedings 2018. British Small Animal Veterinary Association, 2018. http://dx.doi.org/10.22233/9781910443590.28.1.

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Conference papers on the topic "Excision margins"

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Ching-Roa, Vincent D., Chi Huang, Connor Heckman, Xiang Tang, Sherrif Ibrahim, and Michael Giacomelli. "Intraoperative margin evaluation of fresh Mohs excisions using two-photon fluorescence microscopy." In Photonics in Dermatology and Plastic Surgery 2025, edited by Milind Rajadhyaksha and Haishan Zeng. SPIE, 2025. https://doi.org/10.1117/12.3043297.

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Rounds, Cody C., Jaron de Wit, Jasper Vonk, Floris Voskuil, Max J. H. Witjes, and Kenneth M. Tichauer. "Margin status assessment using a ratio-metric angular domain fluorescent imaging approach in patients with head and neck squamous cell carcinoma." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/omp.2023.ow3e.3.

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Many head and neck squamous cell carcinoma surgical patients are left with residual tumor post excision surgery (inadequate margins). We present an imaging strategy capable of rapid margin status assessment to reduce overall surgical burden.
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El-Helou, Etienne, Claudia Stanciu-Pop, Michel Moreau, et al. "MACROSCOPIC EVALUATION OF THE PATHOLOGICAL MARGIN IN PATIENTS WITH BREAST CANCER DURING BREAST-CONSERVING SURGERY." In Brazilian Breast Cancer Symposium 2022. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s2059.

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Objective: Nearly 1/5 of women with breast cancer (BC) treated by breast-conserving surgery (BCS) require reoperation due to positive margins on final pathology. In our hospital practice, intraoperative macroscopic pathological margin evaluation (IMPME) of all lumpectomy specimens is routine. The objectives of the study were to assess the accuracy of the IMPME in a large study population of BC patients treated by BCS. Methods: Patients treated by BCS from 2015 to 2017 for invasive BC were included in a retrospective analysis. The diagnostic accuracy of IMPME in predicting margin involvement wa
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Mullen, R., EJ Macaskill, A. Khalil, et al. "P3-12-04: Involved Anterior Margins after Breast Conserving Surgery: Is Re-Excision Required?" In Abstracts: Thirty-Fourth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 6‐10, 2011; San Antonio, TX. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/0008-5472.sabcs11-p3-12-04.

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Belluco, Rosana Zabulon Feijó, Melissa de Andrade Baqueiro, Vitória Vasconcelos de Lara Resende, Flávio Lúcio Vasconcelos, and Jefferson Lessa Soares de Macedo. "EXTENSIVE DERMATOFIBROSARCOMA PROTUBERANS IN THE CHEST AND BREAST: A CASE REPORT." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1033.

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Dermatofibrosarcoma protuberans (DP) is a neoplasm of the deep layer of the dermis and subcutaneous tissue. It presents a rare incidence and constitutes 0.1% of the malignant tumors. It has local aggressive behavior with slow tumor growth, low metastasis rates of around 5%, but has high rates of local recurrence after surgical excision. The diagnosis is histopathological through biopsy of the lesion, and the fluorescence in situ hybridization (FISH) method can help in selected cases by detecting possible chromosomal rearrangements in the tissue. Physical examination, magnetic resonance imaging
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Clarke, Paula, Henrique Lima Couto, Eduardo Carvalho Pessoa, et al. "The potential role of cavity margins sampling shaving to predict complete tumor resection by vacuum-assisted excision." In Brazilian Breast Cancer Symposium 2024. Mastology, 2024. http://dx.doi.org/10.29289/259453942024v34s1021.

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Objective: The objective of this study was to evaluate the cavity margins sampling shaving (CMSH) as a predictor of complete tumor resection (CR) by VAE. Methodology: This is a retrospective database analysis of 120 ductal carcinoma in situ (DCIS) and invasive cancers (IC) of the breast, smaller than 20 mm (image), submitted to diagnostic VAE-CMSH and standard surgery (SS) from June 2021 to December 2023. VAE definition: more than 12 core samples (CS) with 7G needle or 18 samples with 10G needle. CMSH definition: core sampling the round residual cavity circumference after VAE. CMSH-CS were all
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El-Helou, Etienne, Manar Zaiter, Pauline Delrue, Ahmad Awada, Isabelle Veys, and Catalin-Florin Pop. "INCIDENTAL FINDING OF SOLITARY FIBROUS TUMOR OF MALE BREAST." In Brazilian Breast Cancer Symposium 2022. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s2087.

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Myofibroblastoma (MFB), also known as a solitary fibrous tumor of the breast, is a rare sporadic benign tumor composed of spindle-shaped tumor cells with myoblast differentiation. The most typical presentation is a painless unilateral mass that is not connected to any surrounding structure and seldom surpasses 3 cm in size and should be evaluated by using the triple-assessment approach. They have several subtypes, and a definite diagnosis can only be confirmed safely after surgery using immunohistochemistry. Surgical excision serves an essential diagnostic and therapeutic purpose; MFB has a fa
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Pereira, Antonio Cesar, Rogerio Bizinoto Ferreira, Delio Marques Conde, et al. "OCCULT LESIONS LOCALIZATION AND “IN VIVO” MARGINS EVALUATION OF BREAST CARCINOMA DETECTED BY NEW HYBRID TECHNIQUE USING RADIOFLUORESCENCE—A PILOT STUDY." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2019.

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This pilot study presents a new technique of hybrid marking of non-palpable breast lesion with surgical margins evaluation “in vivo,” which we referred to as FLuorescence And Seed for Hybrid Intraoperative Evaluation (FLASHIE). Seven women, with one lesion each, were submitted to a previous implantation of 125-iodine seed in the center of the suspected area and then were injected with indocyanine green (ICG). During surgery, an optonuclear probe was used to detect gamma radiation and fluorescence. Gamma detection mode was used to locate lesions, and then fluorescence mode, to analyze the ICG c
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Shipp, Dustin, Emad Rakha, Alexey Koloydenko, Douglas Macmillan, Ian Ellis, and Ioan Notingher. "Intra-operative Assessment of Excision margins During Breast Conserving Surgery by Integrated Raman Microscopy and Auto-fluorescence Imaging." In Clinical and Translational Biophotonics. OSA, 2018. http://dx.doi.org/10.1364/translational.2018.ctu4b.5.

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Razvi, K., K. Rothnie, T. Speed, and S. Clark. "EP1085 Surgical margins of large loop excision of the transformation zone: histological comparison with patient characteristics and colposcopists' experience." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.1127.

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