Journal articles: 'Eye lens'

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Hoehenwarter, W., J. Klose, and P. R. Jungblut. "Eye lens proteomics." Amino Acids 30, no. 4 (April 4, 2006): 369–89. http://dx.doi.org/10.1007/s00726-005-0283-9.

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Hoehenwarter, W., J. Klose, and Peter R. Jungblut. "Eye lens proteomics." Amino Acids 37, no. 2 (March 24, 2009): 439. http://dx.doi.org/10.1007/s00726-009-0270-7.

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Asbell, Penny A. "Eye & Contact Lens." Eye & Contact Lens: Science & Clinical Practice 40, no. 1 (January 2014): 1. http://dx.doi.org/10.1097/icl.0000000000000013.

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BEHRENS, R. "Monitoring the eye lens." Acta Ophthalmologica 89, s248 (September 2011): 0. http://dx.doi.org/10.1111/j.1755-3768.2011.2163.x.

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Quinlan, R. A., A. Sandilands, J. E. Procter, A. R. Prescott, A. M. Hutcheson, R. Dahm, C. Gribbon, P. Wallace, and J. M. Carter. "The eye lens cytoskeleton." Eye 13, no. 3 (May 1999): 409–16. http://dx.doi.org/10.1038/eye.1999.115.

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Shibata, Shinsuke, Naoko Shibata, Satoshi Ohtsuka, Yasuo Yoshitomi, Etsuko Kiyokawa, Hideto Yonekura, Dhirendra P. Singh, Hiroshi Sasaki, and Eri Kubo. "Role of Decorin in Posterior Capsule Opacification and Eye Lens Development." Cells 10, no. 4 (April 9, 2021): 863. http://dx.doi.org/10.3390/cells10040863.

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Decorin (DCN) is involved in a variety of physiological and pathological processes. Epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) has been proposed as a major cause for the development of posterior capsule opacification (PCO) after cataract surgery. We investigated the plausible target gene(s) that suppress PCO. The expression of Dcn was significantly upregulated in rat PCO tissues compared to that observed in the control using a microarray-based approach. LECs treated with fibroblast growth factor (FGF) 2 displayed an enhanced level of DCN expression, while LECs treated with transforming growth factor (TGF)β-2 showed a decrease in DCN expression. The expression of tropomyosin 1 (Tpm1), a marker of lens EMT increased after the addition of TGFβ-2 in human LEC; however, upregulation of Tpm1 mRNA or protein expression was reduced in human LECs overexpressing human DCN (hDCN). No phenotypic changes were observed in the lenses of 8- and 48-week-old transgenic mice for lens-specific hDCN (hDCN-Tg). Injury-induced EMT of the mouse lens, and the expression patterns of α smooth muscle actin, were attenuated in hDCN-Tg mice lenses. Overexpression of DCN inhibited the TGFβ-2-induced upregulation of Tpm1 and EMT observed during wound healing of the lens, but it did not affect mouse lens morphology until 48 weeks of age. Our findings demonstrate that DCN plays a significant role in regulating EMT formation of LECs and PCO, and suggest that for therapeutic intervention, maintenance of physiological expression of DCN is essential to attenuate EMT progression and PCO formation.

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Desinta, Rosa, Risalatul Latifah, Rio Imam Santoso, and Bunawas Bunawas. "PEMANTAUAN DOSIS LENSA MATA HP(3) STAF CATHLAB MENGGUNAKAN SOCA DOSIMETER." Prosiding Seminar Si-INTAN 2, no. 1 (July 13, 2022): 69–75. http://dx.doi.org/10.53862/ssi.v2.072022.011.

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MONITORING OF EYE LENS DOSE HP(3) CATHLAB STAFF USING SOCA DOSIMETER. The International Commission on Radiological Protection (ICRP) reduced the cataract threshold dose from 2‒5 Gy to 0.5 Gy, followed by a decrease in the dose limit value (NBD) of the radiation worker's eye lens to 20 mSv/year. Cathlab staff is one of the workers vulnerable to receiving high doses of eye lenses because they work near radiation sources, so staff's eye lens doses need to be monitored. Monitoring is carried out to analyze the dose of eye lenses received by workers and ensure workers are well protected. Eye lens measurement is carried out at Hp(3) or a depth of 3 mm because the lens is sensitive to radiation. Monitoring was carried out for one week on 14 staff (doctors, nurses, and radiographers) and four procedures with an eyepiece dosimeter (SOCA Dosimeter). The eye lens dose obtained for a week ranged from 0.108 – 1.642 mSv, and monitoring per procedure was 0.033 – 0.393 mSv. The annual dose received by workers is based on estimates mostly exceeding the NBD, so tracking with an eye lens dosimeter needs to be done, and eye protection equipment needs to be used to reduce the eye lens dose received. Keywords: Cathlab staff, eye lens dose Hp(3), SOCA dosimeter

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Francis, Peter J., and Anthony T. Moore. "The lens." Eye 13, no. 3 (May 1999): 393–94. http://dx.doi.org/10.1038/eye.1999.112.

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McAvoy, J. W., C. G. Chamberlain, R. U. de Longh, A. M. Hales, and F. J. Lovicu. "Lens development." Eye 13, no. 3 (May 1999): 425–37. http://dx.doi.org/10.1038/eye.1999.117.

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Li, Jiehui, and Qian Zhang. "Design and Simulation of Compound Eye Lens for Visible Light Communication and Illumination." Advances in Condensed Matter Physics 2020 (December 14, 2020): 1–6. http://dx.doi.org/10.1155/2020/6698074.

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We proposed a scheme for designing an optical launch system that can make the light intensity more uniform on the receiving plane via a compound eye lens combined with a sunflower plano-convex lens. The simulation results demonstrate that the light converges on the optical axis after passing through the sunflower-shaped plano-convex lens array and compound eye lens. The divergence angle and central light intensity of the receiving plane are, respectively, 26.57° and 80.50% of the total emitted light power for the array structure of the compact compound eye plano-convex lens, while those are 21.80° and 62.50% for the discrete compound eye lens. From the above results, it can be seen that the compact compound eye lens is more conducive to the uniform distribution of light intensity on the receiving plane compared with the discrete compound eye lens, taking into account the dual application of illumination and communication.

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Inomata, Takenori, Masahiro Nakamura, Masao Iwagami, Akie Midorikawa-Inomata, Jaemyoung Sung, Keiichi Fujimoto, Yuichi Okumura, et al. "Stratification of Individual Symptoms of Contact Lens–Associated Dry Eye Using the iPhone App DryEyeRhythm: Crowdsourced Cross-Sectional Study." Journal of Medical Internet Research 22, no. 6 (June 26, 2020): e18996. http://dx.doi.org/10.2196/18996.

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Background Discontinuation of contact lens use is mainly caused by contact lens–associated dry eye. It is crucial to delineate contact lens–associated dry eye's multifaceted nature to tailor treatment to each patient’s individual needs for future personalized medicine. Objective This paper aims to quantify and stratify individual subjective symptoms of contact lens–associated dry eye and clarify its risk factors for future personalized medicine using the smartphone app DryEyeRhythm (Juntendo University). Methods This cross-sectional study included iPhone (Apple Inc) users in Japan who downloaded DryEyeRhythm. DryEyeRhythm was used to collect medical big data related to contact lens–associated dry eye between November 2016 and January 2018. The main outcome measure was the incidence of contact lens–associated dry eye. Univariate and multivariate adjusted odds ratios of risk factors for contact lens–associated dry eye were determined by logistic regression analyses. The t-distributed Stochastic Neighbor Embedding algorithm was used to depict the stratification of subjective symptoms of contact lens–associated dry eye. Results The records of 4454 individuals (median age 27.9 years, SD 12.6), including 2972 female participants (66.73%), who completed all surveys were included in this study. Among the included participants, 1844 (41.40%) were using contact lenses, and among those who used contact lenses, 1447 (78.47%) had contact lens–associated dry eye. Multivariate adjusted odds ratios of risk factors for contact lens–associated dry eye were as follows: younger age, 0.98 (95% CI 0.96-0.99); female sex, 1.53 (95% CI 1.05-2.24); hay fever, 1.38 (95% CI 1.10-1.74); mental illness other than depression or schizophrenia, 2.51 (95% CI 1.13-5.57); past diagnosis of dry eye, 2.21 (95% CI 1.63-2.99); extended screen exposure time >8 hours, 1.61 (95% CI 1.13-2.28); and smoking, 2.07 (95% CI 1.49-2.88). The t-distributed Stochastic Neighbor Embedding analysis visualized and stratified 14 groups based on the subjective symptoms of contact lens–associated dry eye. Conclusions This study identified and stratified individuals with contact lens–associated dry eye and its risk factors. Data on subjective symptoms of contact lens–associated dry eye could be used for prospective prevention of contact lens–associated dry eye progression.

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Sidhu, Talvir, Arjun Desai, Meghal Gagrani, and Tanuj Dada. "Phacomorphic glaucoma in a high myope with phakic intraocular lens." BMJ Case Reports 12, no. 2 (February 2019): e227096. http://dx.doi.org/10.1136/bcr-2018-227096.

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We report a case of a young, one-eyed woman with high myopia who presented to our emergency department with sudden onset painful diminution of vision in the right eye after undergoing laser treatment. Her right eye had a phakic intraocular lens (pIOL) implantation 4 years back and her left eye had absent light perception. She was diagnosed as right eye lens induced secondary angle closure glaucoma with pIOL touching the corneal endothelium and left eye atrophic bulbi. She was admitted under eye emergency for medical intraocular pressure control followed by pIOL explantation with lens aspiration of the cataractous lens and posterior chamber intraocular lens implantation.

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O'Gallagher, M. K., M. A. Lagan, C. P. Mulholland, M. Parker, G. McGinnity, and E. M. McLoone. "Paediatric intraocular lens implants: accuracy of lens power calculations." Eye 30, no. 9 (July 29, 2016): 1215–20. http://dx.doi.org/10.1038/eye.2016.163.

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Nelkin, Dorothy. "Eye to the rosy lens." Nature 313, no. 6005 (February 1985): 825. http://dx.doi.org/10.1038/313825a0.

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Saito, Megumi, and Kiyoshi Sugiyama. "Gangliosides of rat eye lens." Life Sciences 67, no. 15 (September 2000): 1891–99. http://dx.doi.org/10.1016/s0024-3205(00)00774-8.

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Gibson, Tony. "Dry eye or contact lens?" Optician 2020, no. 8 (August 2020): 229490–1. http://dx.doi.org/10.12968/opti.2020.8.229490.

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Bozovic, Predrag, Olivera Ciraj-Bjelac, Jelena Stankovic-Petrovic, Danijela Arandjic, and Sandra Ceklic. "Utilizing Monte Carlo simulations in estimation of occupational eye lens dose based on whole body dosemeter in interventional cardiology and radiology." Nuclear Technology and Radiation Protection 33, no. 4 (2018): 375–79. http://dx.doi.org/10.2298/ntrp180730005b.

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Medical staff performing interventional procedures in cardiology and radiology is considered to be a professional group exposed to high doses of ionizing radiation. With new epidemiological evidences and recently reduced eye lens dose limit, dose assessment to the lens of the eye, in the interventional cardiology, has become one of the most challenging research topics. This paper presents results of the eye lens dose assessment in interventional cardiology obtained by means of the computational dosimetry. Since placing and wearing the dedicated eye lens dosimeter is encumbering for the staff, Monte Carlo simulation provides an accurate and efficient method for obtaining an indication of doses to the eye lenses. Eye lens doses were estimated for three typical beam projections (PA, LAO, and RAO) and tube voltages ranging from 80 kV to 110 kV, with different protective equipment setups, for the first operator position. Simulations were carried out using MCNPX code. Results revealed that a whole body dosimeter worn at the thyroid center position gives the best estimate of the eye lens dose with a spread from 11 % to 18 % for the left eye. Corresponding average conversion coefficient from whole body to the eye lens dose is estimated to be 0.18.

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Imai, Shinya, Manabu Akahane, Yuji Ogata, Nobuyoshi Tanki, Hitoshi Sato, and Kazuma Tameike. "Occupational eye lens dose in endoscopic retrograde cholangiopancreatography using a dedicated eye lens dosimeter." Journal of Radiological Protection 41, no. 3 (August 19, 2021): 579–89. http://dx.doi.org/10.1088/1361-6498/ac091f.

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Lubis, Rodiah Rahmawaty, and Monica Tumiar Hanna Gultom. "The Correlation between Daily Lens Wear Duration and Dry Eye Syndrome." Open Access Macedonian Journal of Medical Sciences 6, no. 5 (May 18, 2018): 829–34. http://dx.doi.org/10.3889/oamjms.2018.215.

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AIM: To analyze the correlation between the daily lens wear duration and dry eye syndrome.SUBJECTS AND METHODS: This study was an analytic cross sectional study using consecutive sampling conducted among the students in Economy and Bussiness Faculty and Faculty of Humanities in University of Sumatera Utara aged between 17 to 23 that wore contact lens continously for at least a year and 5 days a week. The symptoms were assessed using Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) and interview about their contact lens comfort; eye drops usage, contact lens washing habit, daily circumstances, places to buy contact lens and personal experince in wearing contact lens.RESULTS: The questionnaire was completed by 53 students. All of them were female and wore softlens wearers. The mean duration of daily wear was 8.19 ± 2.20 hours. The most common symptom experienced was dry eye and the least symptom experienced was removing lens. The most frequent symptom experienced was closing eyes and the least frequent symptom experienced was removing lenses. This study used Exact Test as analysis statistic method. The result was p > 0.05 which means there is no correlation between daily lens wear duration and dry eye syndrome.CONCLUSION: This study showed that dry eye syndrome was not correlated with daily lens wear duration, but affected by many factors such as contact lens, lens care solution, eye drops usage and environment.

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Markiewicz, Ewa, Stephen Barnard, Jackie Haines, Margaret Coster, Orry van Geel, Weiju Wu, Shane Richards, et al. "Nonlinear ionizing radiation-induced changes in eye lens cell proliferation, cyclin D1 expression and lens shape." Open Biology 5, no. 4 (April 2015): 150011. http://dx.doi.org/10.1098/rsob.150011.

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Elevated cataract risk after radiation exposure was established soon after the discovery of X-rays in 1895. Today, increased cataract incidence among medical imaging practitioners and after nuclear incidents has highlighted how little is still understood about the biological responses of the lens to low-dose ionizing radiation (IR). Here, we show for the first time that in mice, lens epithelial cells (LECs) in the peripheral region repair DNA double strand breaks (DSB) after exposure to 20 and 100 mGy more slowly compared with circulating blood lymphocytes, as demonstrated by counts of γH2AX foci in cell nuclei. LECs in the central region repaired DSBs faster than either LECs in the lens periphery or lymphocytes. Although DSB markers (γH2AX, 53BP1 and RAD51) in both lens regions showed linear dose responses at the 1 h timepoint, nonlinear responses were observed in lenses for EdU (5-ethynyl-2′-deoxy-uridine) incorporation, cyclin D1 staining and cell density after 24 h at 100 and 250 mGy. After 10 months, the lens aspect ratio was also altered, an indicator of the consequences of the altered cell proliferation and cell density changes. A best-fit model demonstrated a dose-response peak at 500 mGy. These data identify specific nonlinear biological responses to low (less than 1000 mGy) dose IR-induced DNA damage in the lens epithelium.

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Schueler, Beth A., and Kenneth A. Fetterly. "Eye protection in interventional procedures." British Journal of Radiology 94, no. 1126 (October 1, 2021): 20210436. http://dx.doi.org/10.1259/bjr.20210436.

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Data suggest that radiation-induced cataracts may form without a threshold and at low-radiation doses. Staff involved in interventional radiology and cardiology fluoroscopy-guided procedures have the potential to be exposed to radiation levels that may lead to eye lens injury and the occurrence of opacifications have been reported. Estimates of lens dose for various fluoroscopy procedures and predicted annual dosages have been provided in numerous publications. Available tools for eye lens radiation protection include accessory shields, drapes and glasses. While some tools are valuable, others provide limited protection to the eye. Reducing patient radiation dose will also reduce occupational exposure. Significant variability in reported dose measurements indicate dose levels are highly dependent on individual actions and exposure reduction is possible. Further follow-up studies of staff lens opacification are recommended along with eye lens dose measurements under current clinical practice conditions.

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Inglis, A. C., and W. N. Wykes. "Recurrent lens epithelial cell proliferation with an AcrySof lens implant." Eye 14, no. 5 (September 2000): 793–94. http://dx.doi.org/10.1038/eye.2000.211.

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Funkenbusch, GuoMing T., and Richard C. Benson. "The Conformity of a Soft Contact Lens on the Eye." Journal of Biomechanical Engineering 118, no. 3 (August 1, 1996): 341–48. http://dx.doi.org/10.1115/1.2796016.

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An axisymmetric elastic shell deformation model has been created to predict the conformity of a soft contact lens when pressed against the eye. Regions of contact and gap may be predicted, and the nonuniform reaction pressure between the lens and eye may also be found. This is important for issues like abrasion and comfort. Bending, membrane and transverse shear loads within the lens are also computed. Commercial soft contact lenses and a representative eye shape are used for the examples. We find that the uniformity of loading against the eye is strongly affected by the degree to which the lens is shaped to fit the eye, and relatively unaffected by the thickness of the lens.

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Kowatari, Munehiko, Hayo Zutz, and Oliver Hupe. "APPLICABILITY OF A COMMERCIALLY AVAILABLE ACTIVE EXTREMITY DOSE-RATE METER TO EYE LENS DOSE MONITORING." Radiation Protection Dosimetry 192, no. 4 (December 2020): 460–72. http://dx.doi.org/10.1093/rpd/ncab009.

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Abstract A commercially available active extremity dosemeter is a promising candidate for medical staff aid individual monitoring of the eye lens. We investigated the applicability of the newly developed active extremity dosemeter, which uses a low-energy photon probe, to eye lens dose monitoring by performing a complete characterization of the dosemeters. Performance tests revealed that the active extremity dosemeter would overestimate personal dose equivalent, Hp(3), when the probe is worn close to the lens of the eye of a medial worker without any improvement in the response. Introducing an appropriate filter into the probe for low-energy photon has proven to improve the response. The dosemeter then satisfies the criteria of the personal dosemeter for eye lens dosimetry and can be applicable to individual monitoring of eye lens dose. This article also discusses the applicability of the dosemeter to area monitoring for decision making regarding additional monitoring of the eye lens and the extremities.

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Manoppo, Rillya. "Sindroma Marfan – Laporan Kasus." JURNAL BIOMEDIK (JBM) 10, no. 3 (December 18, 2018): 199. http://dx.doi.org/10.35790/jbm.10.3.2018.21988.

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Abstract: Marfan's syndrome is a FBN1 gene mutation that encodes a connective tissue protein, fibrillin-1. Patients usually present with multiple defects including mayor ocular system abnormalities such as ectopic lens and minor criteria such as flat normal cornea, various axial lengths, ciliary hypoplasia, and myopia. We reported a case of a 6-year-old boy with vision complaint since one year ago. Ophthalmological examination revealed 6/60 right eye vision and 1/60 left eye vision. The pressure of the right eyeball was 15 mmHg and of the left eyeball was 13 mmHg. Eye vision could not be corrected with lenses. There were normal eyeball movements to all directions. Examination of the anterior segment showed no injection, clear cornea, and clear anterior chamber. There were superonasal subluxation of the right eye lens with zonular pull and superotemporal subluxation of the left eye lens with zonular pull. Examination of the posterior segment showed positive non-uniform fundus reflex, however, examination of the vitreous body, retina, and macula was difficult to evaluate. The patient was treated with lens extraction and was advised to come to the eye clinic every month for further evaluation of the eye ball pressure and ophthalmological examination as well as the possibility of further intervention treatment such as anterior lens implant in the anterior chamber.Keywords: Marfan syndrome, ectopic lensAbstrak: Sindrom Marfan adalah mutasi gen FBN1 yang mengkode protein jaringan ikat yang disebut fibrilin-1. Pasien biasanya datang dengan cacat multipel termasuk kelainan pada sistem okular yang meliputi kriteria mayor berupa ektopia lentis dan kriteria minor berupa kornea normal datar, peningkatan panjang aksial, hipoplasia silia, dan miopia. Kami melaporkan kasus seorang anak laki-laki berusia 6 tahun dengan keluhan penglihatan kedua mata kabur sejak 1 tahun lalu. Pada pemeriksaan oftalmologik didapatkan visus mata kanan 6/60, visus mata kiri 1/60, tekanan bola mata kanan 15 mmHg, dan tekanan bolamata kiri 13 mmHg. Visus kedua mata tidak dapat dikoreksi dengan menggunakan lensa. Gerakan bola mata baik ke segala arah. Pemeriksaan segmen anterior menunjukkan tidak terdapat injeksi, kornea jernih, dan bilik mata depan jernih. Lensa mata kanan mengalami subluksasi ke arah superior nasal dengan tarikan zonula Zinii sedangkan lensa mata kiri mengalami subluksasi ke arah superior temporal dengan tarikan zonula Zinii. Pemeriksaan segmen posterior kedua mata didapatkan refleks fundus positif non-uniform, sedangkan pemeriksaan untuk badan vitreus, retina dan makula sulit dievaluasi. Tindakan yang dilakukan berupa ekstraksi lentis. Pasien diminta untuk kontrol berkala di poliklinik mata setiap bulan untuk menilai tekanan bola mata dan status oftalmologiknya serta kemungkinan intervensi lanjutan seperti pemasangan lensa anterior pada bilik mata depan.Kata kunci: sindrom Marfan, ektopia lentis

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Liang, Cheng-Loong, Meng-Wei Ho, Kang Lu, Yu-Duan Tsai, Po-Chou Liliang, Kuo-Wei Wang, and Han-Jung Chen. "An investigation of eye lens dose of stereotactic radiosurgery for trigeminal neuralgia using Leksell Gamma Knife model C." Journal of Neurosurgery 105, Supplement (December 2006): 112–16. http://dx.doi.org/10.3171/sup.2006.105.7.112.

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ObjectThe authors conducted a study to assess the eye lens dosimetry in trigeminal neuralgia (TN) treatment when using the Leksell Gamma Knife model C.MethodsPhantom studies were used to measure the maximal dose reaching the eye lens with and without eye shielding. Six consecutive patients with TN were evaluated for Gamma Knife surgery (GKS). The maximum prescribed dose of 80 Gy was delivered with a single shot using the 4-mm collimator helmet. High-sensitivity thermoluminescence dosimeter chips (TLDCs) were used to measure the dosimetry.In vitro, the Leksell GammaPlan (LGP) system predicted the mean maximal doses of 1.08 ± 0.08 and 0.15 ± 0.01 Gy (mean ± standard deviation) to the lens ipsilateral to the treated trigeminal nerve without and with eye shielding, respectively. The TLDCs-measured dosimetry indicated the mean maximal doses of 1.12 ± 0.09 and 0.17 ± 0.01 Gy without and with eye shielding, respectively. The maximal doses to the lens contralateral to the nerve were similar.In vivo, the LGP predicted the mean maximal doses to the lens ipsilateral to the treated nerve as 1.1 ± 0.07 and 0.16 ± 0.02 Gy, respectively, without and with eye shielding. The dosimetry measured by TLDCs indicated the mean maximal dose to the lens ipsilateral to the treated nerve as 0.17 ± 0.02 Gy with eye shielding. The mean maximal doses to the lens contralateral to the nerve were similar. Using the 110 and 125˚ gamma angles, the LGP predicted the mean maximal doses of 0.32 ± 0.04 and 0.12 ± 0.04 Gy to the lens without and with eye shielding, respectively.Conclusions Patients with TN undergoing GKS without eye shielding may develop cataracts due to the high radiation dose to the eye lenses. The authors suggest the routine use of bilateral eye shielding for the patients.

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Teng, Zhongbin, Mingzhe Song, Senlin Liu, Kexin Wei, and Yuntao Liu. "CALCULATION OF THE DOSE CONVERSION COEFFICIENTS FOR CHINESE EYE LENS UNDER PHOTON EXPOSURE." Radiation Protection Dosimetry 197, no. 3-4 (December 2021): 163–74. http://dx.doi.org/10.1093/rpd/ncab175.

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Abstract In this work, the conversion coefficients from air kerma to the eye lens dose were calculated for photon exposures using the detailed eye and head Monte-Carlo (MC) model with the Chinese adult parameters. To verify the MC model and the simulation method, the conversion coefficients from fluence to the eye lens dose for mono-energy electrons (0.7–12 MeV) were calculated and compared with other studies. Then the conversion coefficients from air kerma to the doses in the entire lens and in the sensitive volume were calculated, respectively, for mono-energy photons (0.01–50 MeV) at different incidence angles (0–90°, in step of 15°). A small difference was found between the calculated conversion coefficient and the ICRP recommended value. The difference could be mainly due to the difference in their geometry characteristic of the eye and head models. In addition, the uncertainty analysis of the calculated conversion coefficients was performed in detail. The calculated dose conversion coefficient of the eye lens can be used to evaluate the eye lens dose for Chinese occupational staffs in external photon fields. And it can be used to determine the personal absorbed dose in the eye lens Dp lens in photon reference radiation fields.

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Maloof, Anthony J., Rajni Jain, Marie Restori, and Jullian D. Stevens. "Silicone intraocular lens compression and double lens implants in diseased eyes." Eye 14, no. 5 (September 2000): 736–41. http://dx.doi.org/10.1038/eye.2000.194.

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Lan, Fang-Fang, and Lu Gan. "Application of piggy-back lens in the correction of severe keratoconus: A case study." Technology and Health Care 29, no. 4 (July 9, 2021): 813–22. http://dx.doi.org/10.3233/thc-212889.

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OBJECTIVE: This is a case study on the application of a piggy-back lens in the correction of severe keratoconus. METHODS: From the results of general eye examination, refractive state examination, and corneal morphology examination on the patient, it was determined that corneal protrusion and deformation of the right eye were obvious. The right eye was corrected using a piggy-back lens and the left eye with a rigid gas-permeable contact lens (RGPCL) alone. RESULTS: The right-eye lens fit well and the lens coverage was good. Both the static and dynamic fit results for the left-eye lens were good. After wearing the glasses for one month, the patient attended a review and stated that the lenses were comfortable to wear. The patient’s vision was good after wearing the lenses. No obvious congestion was found in the conjunctiva under a slit lamp. The effects on both eyes of wearing RGPCLs were favorable. The corneal curvature reduced and the corneal thickness only changed to a small degree. CONCLUSION: For keratoconus patients, application of a piggy-back lens can improve corrected visual acuity, comfort levels, and safety, prolong the wearing time, and enhance the effect of orthokeratology.

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D’Avino, Vittoria, Leopoldo Angrisani, Giuseppe La Verde, Mariagabriella Pugliese, Adelaide Raulo, Giuseppe Sabatino, and Fulvio Coppola. "New Eye Lens Dose Limit: Status of Knowledge in Campania Hospitals." International Journal of Environmental Research and Public Health 16, no. 18 (September 17, 2019): 3450. http://dx.doi.org/10.3390/ijerph16183450.

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The International Commission on Radiation Protection (ICRP) in 2011 recommended the lowering of the annual eye lens dose limit from 150 mSv/year to 20 mSv/year in order to reduce the risk of X-ray-induced lens opacity in medical staff. The purpose of this study was to assess the status of knowledge of the new eye lens dose limit and of the radioprotection culture among operators. To this end, a questionnaire was administered to physicians, X-ray technicians, and nurses working in five hospitals of the Campania region, Italy. A total of 64 questionnaires were collected in the hospital departments in which procedures involving ionizing radiation were routinely performed. The data analyzed yielded the following results: 12 operators affirmed to know the new eye lens dose limit, 53 operators routinely wore lead aprons, and 23 operators used lead glasses. Four workers performed eye lens dosimetry through specific dosimeters. A significant lack of knowledge of the reduced eye lens dose limit suggests the need to implement radioprotection-training programs aimed at raising awareness about the importance of health care in the workplace and at reducing the risk of radio-induced effects to the eye lens.

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Božović, Predrag, Olivera Ciraj-Bjelac, and Jelena Stanković Petrović. "OCCUPATIONAL EYE LENS DOSE ESTIMATED USING WHOLE-BODY DOSEMETER IN INTERVENTIONAL CARDIOLOGY AND RADIOLOGY: A MONTE CARLO STUDY." Radiation Protection Dosimetry 185, no. 2 (January 9, 2019): 135–42. http://dx.doi.org/10.1093/rpd/ncy283.

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Abstract Medical personnel performing interventional procedures in cardiology and radiology is considered to be a professional group exposed to high doses of ionizing radiation. Reduction of the eye lens dose limit made its assessment in the interventional procedures one of the most challenging topics. The objective of this work is to assess eye lens doses based on the whole-body doses using methods of computational dosimetry. Assessment included different C-arm orientations (PA, LAO and RAO), tube voltages (80 –110 kV) and efficiency of different combinations of protective equipment used in interventional procedures. Center position at the height of the thyroid gives best estimate of eye lens dose, with spreads of 11% (13%), 13% (17%) and 14% (13%) for the left (right) eye lens. The conversion factors of 1.03 (0.83), 1.28 (1.06) and 1.36 (1.06) to convert whole body to eye lens dose were derived for positions of first operator, nurse and radiographer, respectively. The eye lens dose reduction factors for different combinations of applied protective equipment are 178, 5 and 6, respectively.

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Mandal, Sohini, Pranita Sahay, Manasi Tripathi, and Prafulla Kumar Maharana. "Complications following implantation of posterior chamber phakic intraocular lens (pIOL)." BMJ Case Reports 15, no. 12 (December 2022): e253876. http://dx.doi.org/10.1136/bcr-2022-253876.

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A male patient in his 20s presented with right eye aphakic corneal decompensation and left eye intumescent cataract with phakic intraocular lens (pIOL) lenticular touch. He had a history of pIOL implantation in both eyes 6 months ago. On first postoperative day, uncorrected distance visual acuity was 20/400 and 20/20 in right and left eye, respectively. Postoperatively, a diagnosis of right eye toxic anterior segment syndrome (TASS) was made and pIOL was explanted. Subsequently, the patient developed intumescent cataract for which lens aspiration with posterior chamber intraocular lens (PCIOL) implantation was performed in the right eye. Ongoing uveitis with membrane formation warranted PCIOL explantation. The patient developed aphakic corneal decompensation in the right eye and underwent penetrating keratoplasty with intrascleral haptic fixation of an intraocular lens. Central pIOL-lenticular touch with intumescent cataract was diagnosed in the left eye for which pIOL explant with lens aspiration and PCIOL was done. TASS and post-pIOL cataract are rare but vision-threatening complications require judicious management for visual rehabilitation.

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Fulvio IM, Fucilli, Giovanni Giuseppe Di, Mastrorocco Alessandro, Ninni Matteo, Loprete Piero, Crudis Isa De, Marano Massimiliano, Santomauro Antonio, and Fucilli Fabio. "Investigation of the effectiveness of ECOLAB ’Drape ArmourTM’ Radiation Protection in limiting eye-lens doses of healthcare personnel exposed to ionizing radiation during gastroenterology - interventional radiology procedures." Global Journal of Cancer Therapy 8, no. 1 (October 20, 2022): 046–50. http://dx.doi.org/10.17352/2581-5407.000048.

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Objectives: To investigate the efficiency of the ECOLAB “Drape ArmourTM” device in limiting the eye-lens doses absorbed by healthcare personnel exposed to ionizing radiation, in a four-month trial during gastroenterology interventional radiology procedures. Methods: Eyelens doses measured with eye-lens dosimeters calibrated in terms of equivalent dose at 3 mm depth ( Hp(3) ) were collected and analyzed since 2016 along with the irradiation parameters (Dose Area Product - DAP). The eye-lens doses received during the four-month trial, have been compared with doses normally received, in the same conditions of irradiation, in the absence of the protection drape. Results: During the period of use of Drape ArmourTM, the average dose to the eye lens was estimated to be 0.73 mSv (St.dev = 0.40 mSv). The average dose to the eye lens, measured in the same four-month period, across different years from 2017 to 2021, was equal to 1.30 mSv (st. dev = 0.35 mSv). Conclusions: Results suggest the effectiveness of Drape ArmourTM in containing the doses to the eye lens. Keypoint: Limiting eye-lens doses to a maximum value of 20 mSv/year is a real challenge, especially in interventional radiologic facilities. The use of suitable radio-opaque drapes may help healthcare workers involved in such facilities. The aim of the work is to evaluate the efficiency of the ECOLAB “Drape ArmourTM” sterile mono-use drape.

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Kim, Hui kyung, Yeon ji Jo, and Jong Soo Lee. "Contact Lens-induced Acute Red Eye." Journal of the Korean Ophthalmological Society 63, no. 11 (November 15, 2022): 895–902. http://dx.doi.org/10.3341/jkos.2022.63.11.895.

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It is important to understand the acute and chronic complications of prolonged contact lens use; treatment of acute problems is more effective than treatment of chronic reactions because it is difficult to restore corneal tissue. Contact lens-induced acute red eye (CLARE) is an acute inflammatory reaction of the cornea and conjunctiva triggered by contact lenses. CLARE recurrence is common; differential diagnosis from serious eye diseases that can compromise visual acuity is important. CLARE must be appropriately treated and patients must be educated in terms of safe contact lens wearing and storage.

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Bhandari, Ajay, Ankit Bansal, and Niraj Sinha. "Numerical modeling of therapeutic lens drug delivery in the anterior human eye for the treatment of primary open-angle glaucoma." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 234, no. 9 (July 7, 2020): 942–54. http://dx.doi.org/10.1177/0954411920934960.

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A numerical model of drug delivery from a therapeutic lens in the anterior portion of the human eye has been developed for a more effective treatment plan of primary open-angle glaucoma. The numerical model takes into account the drug diffusion through the therapeutic lens along with heat transfer and aqueous humor flow in different orientations of the human eye (supine (two-dimensional) as well as standing (three-dimensional)). Results illustrate that the drug diffuses through the therapeutic lens to the cornea and is convected into the anterior chamber of the eye due to the temperature gradient across the eye. In addition, eye orientation significantly affects drug delivery with supine orientation providing better and uniform drug exposure in different target regions of the eye as compared to standing in the case of the therapeutic lens. Furthermore, a comparison of the therapeutic efficacy of the therapeutic lens has been done with topical administration and the drug uptake results from both the drug delivery modes have been validated with the experimental data reported in the literature. The developed model may help ophthalmologists to comprehend the transport and retention of different drugs in different domains and orientations of the human eye when administered through a therapeutic lens.

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Gong, J. W. L., U. O'Colmain, and C. J. MacEwen. "Opaque intraocular lens implantation." Eye 29, no. 7 (February 27, 2015): 978–80. http://dx.doi.org/10.1038/eye.2015.15.

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Hope-Ross, M., and D. Mooney. "Intraocular lens power calculation." Eye 2, no. 4 (July 1988): 367–69. http://dx.doi.org/10.1038/eye.1988.67.

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Halliday, B. L. "Manufacture of epikeratophakia lens." Eye 2, no. 4 (July 1988): 395–99. http://dx.doi.org/10.1038/eye.1988.72.

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Bron, A. J., J. Sparrow, N. A. P. Brown, J. J. Harding, and R. Blakytny. "The lens in diabetes." Eye 7, no. 2 (March 1993): 260–75. http://dx.doi.org/10.1038/eye.1993.60.

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Zagorska, A., V. Gelev, I. Jeleva, N. Stoyanov, and D. Ivanova. "Eye lens dose assessment in interventional cardiology." Bulgarian Cardiology 28, no. 3 (September 30, 2022): 96–105. http://dx.doi.org/10.3897/bgcardio.28.e89578.

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Introduction: Medical professionals performing fluoroscopy guided interventional procedures in cardiology are exposed to a risk of radiation induced cataract, especially if the eye lens dose exceeds the annual dose limit of 20 mSv. Aim: The aim of the current study is to measure the eye lens exposure in three interventional cardiology departments, to analyze the relationship between patient dose and eye lens dose and to study the effectiveness of lead goggles without side protection. Material and methods: Measurements were performed in three departments with participation of 4 interventional cardiologists and 6 nurses. The exposure of the eye lens was measured with EYE-DTM (Radcard) passive dosimeters. Results: For nurses the annual eye lens dose varied from 1.6 mSv to 4.3 mSv. For the interventional cardiologists the results were between 3.2 mSv and 31.4 mSv. The dose reduction factor of the studied safety goggles without side protection is 1 and 1.1. Conclusions: There is a risk of exceeding the annual exposure limit of 20 mSv among interventional cardiologists The eye lens exposure depends on the workload and the clinical complexity of the procedures, as well as on the use of radiation protection devices. Due to the specifics of the procedures, the use of goggles with side protection is recommended. The eye lens dose for nurses is lower than the annual limit, which can be explained with the larger distance between the patient and the nurses and partial shielding by the main operator. Lead glasses without side shielding are not recommended because the exposure occurs from the side.

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Langenbucher, Achim, Nóra Szentmáry, Alan Cayless, Veronika Röggla, Christina Leydolt, Jascha Wendelstein, and Peter Hoffmann. "Similarity of eyes in a cataractous population—How reliable is the biometry of the fellow eye for lens power calculation?" PLOS ONE 17, no. 6 (June 30, 2022): e0269709. http://dx.doi.org/10.1371/journal.pone.0269709.

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Background In some situations it is necessary to use biometry from the fellow eye for lens power calculation prior to cataract surgery. The purpose of this study was to analyse the lateral differences in biometric measurements and their impact on the lens power calculation. Methods The analysis was based on a large dataset of 19,472 measurements of 9736 patients prior to cataract surgery with complete biometric data of both left and right eyes extracted from the IOLMaster 700. After randomly indexing the left or right eye as primary (P) and secondary (S), the differences between S and P eye were recorded and analysed (Keratometry (RSEQ), total keratometry (TRSEQ) and back surface power (BRSEQ)), axial length AL, corneal thickness CCT, anterior chamber depth ACD, lens thickness LT). Lens power was calculated with the Castrop formula for all P and S eyes, and the refraction was predicted using both the P and S eye biometry for the lens power calculation. Results Lateral differences (S-P, 90% confidence interval) ranged between -0.64 to 0.63 dpt / -0.67 to 0.66 dpt / -0.12 to 0.12 dpt for RSEQ / TRSEQ / BRSEQ. The respective difference in AL / CCT / ACD / LT ranged between -0.46 to 0.43 mm / -0.01 to 0.01 mm / -0.20 to 0.20 mm / -0.13 to 0.14 mm. The resulting difference in lens power and predicted refraction ranged between -2.02 to 2.00 dpt and -1.36 to 1.30 dpt where the biometry of the S eye is used instead of the P eye. The AL and RSEQ were identified as the most critical parameters where the biometry of the fellow eye is used. Conclusion Despite a strong similarity of both eyes, intraocular lens power calculation with fellow eye biometry could yield different results for the lens power and finally for the predicted refraction. In 10% of cases, the lens power derived from the S eye deviates by 2 dpt or more, resulting in a refraction deviation of 1.36 dpt or more.

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Jovanovic, Milos, and Ivan Stefanovic. "Spontaneous dislocation of a transparent lens to the anterior chamber: A case report." Srpski arhiv za celokupno lekarstvo 138, no. 7-8 (2010): 486–88. http://dx.doi.org/10.2298/sarh1008486j.

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Introduction. The causes leading to dislocation of the natural lenses are different involving injuries, hereditary diseases and spontaneous dislocation. Spontaneous dislocation of a transparent natural lens is extremely rare, especially dislocation of the anterior eye chamber. We report a case of spontaneous dislocation of the transparent natural lens to the anterior eye chamber in a patient who had no history of eye injuries. Case Outline. The patient was a 17-year old boy. Lens dislocation was spontaneous, and the patient presented for ophthalmological consultation due to a sudden vision impairment of the left eye. Biomicroscopic examination verified that the transparent lens was in the anterior chamber, and it was spherophakia of lesser diameter; there were no signs of increased intraocular pressure, as typically expected in lens dislocation to the anterior chamber. The patient was operated on in general anaesthesia. Surgery involved intracapsular extraction of the dislocated lens through a corneoscleral incision. Conclusion. This case report shows that a spontaneous dislocation of the natural lens may occur in younger people. The dislocated spherophakic lens to the anterior eye chamber did not contribute to the rise of the intraocular pressure and development of acute glaucoma. The acute glaucoma resulted from the pilocarpine narrowing of the pupil due to pupillary block. The intracapsular instrumental extraction of the dislocated transparent lens from the anterior chamber was successfully completed through a corneoscleral incision.

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Slingsby, Christine, Alan Simpson, Astrid Ferszt, Orval A. Bateman, and Veerapaneni Nalini. "Molecular interactions in the eye lens." Biochemical Society Transactions 19, no. 4 (November 1, 1991): 853–58. http://dx.doi.org/10.1042/bst0190853.

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Principi, S., C. Delgado Soler, M. Ginjaume, M. Beltran Vilagrasa, J. J. Rovira Escutia, and M. A. Duch. "Eye lens dose in interventional cardiology." Radiation Protection Dosimetry 165, no. 1-4 (March 24, 2015): 289–93. http://dx.doi.org/10.1093/rpd/ncv051.

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Ferrari, Paolo, Francesca Mariotti, and Lorenzo Campani. "EDEL: ENEA DOSEMETER FOR EYE LENS." Radiation Protection Dosimetry 170, no. 1-4 (July 12, 2015): 145–49. http://dx.doi.org/10.1093/rpd/ncv369.

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Werner, Oswald. "Uses of a Fish-Eye Lens." Field Methods 12, no. 2 (May 2000): 153–61. http://dx.doi.org/10.1177/1525822x0001200204.

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Hughes, Ciarán, Patrick Denny, Edward Jones, and Martin Glavin. "Accuracy of fish-eye lens models." Applied Optics 49, no. 17 (June 7, 2010): 3338. http://dx.doi.org/10.1364/ao.49.003338.

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Wagner, David L., and Thomas A. Walkiewicz. "When the eye meets the lens." Physics Teacher 38, no. 8 (November 2000): 474–75. http://dx.doi.org/10.1119/1.1329086.

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Edge, R. D. "The optics of the eye lens." Physics Teacher 27, no. 5 (May 1989): 392–93. http://dx.doi.org/10.1119/1.2342807.

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Augusteyn, R. C., and A. Stevens. "Macromolecular structure of the eye lens." Progress in Polymer Science 23, no. 3 (January 1998): 375–413. http://dx.doi.org/10.1016/s0079-6700(98)80008-7.

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Journal articles on the topic 'Eye lens'

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